Mus musculus

31 known processes

Mll3

myeloid/lymphoid or mixed-lineage leukemia 3

(Aliases: KMT2C,mKIAA1506,HALR,KIAA1506,E330008K23Rik)

Mll3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone lysine methylationGO:0034968500.960
Human Worm Fly
gene silencing by mirnaGO:0035195100.946
chromatin organizationGO:00063252060.936
habituationGO:004695930.877
macromolecule methylationGO:00434141200.828
dna methylationGO:0006306430.762
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288120.667
protein methylationGO:0006479810.627
methylationGO:00322591340.619
histone methylationGO:0016571710.615
gene silencingGO:0016458380.609
Worm
uterus morphogenesisGO:006103820.566
histone modificationGO:00165701590.555
hypermethylation of cpg islandGO:004402730.546
ribonucleoside triphosphate catabolic processGO:00092031990.498
covalent chromatin modificationGO:00165691630.473
cellular response to dna damage stimulusGO:00069742070.464
histone h3 k4 trimethylationGO:008018250.442
positive regulation of dna templated transcription elongationGO:003278620.427
gene silencing by rnaGO:0031047190.422
Worm
histone h3 k4 methylationGO:0051568230.404
Human Worm Fly
dna metabolic processGO:00062593030.365
purine ribonucleoside catabolic processGO:00461302050.348
chromatin modificationGO:00165681870.340
chromatin silencingGO:0006342150.336
peptidyl lysine methylationGO:0018022290.331
Human Worm Fly
organonitrogen compound catabolic processGO:19015652640.327
purine ribonucleotide catabolic processGO:00091542080.319
negative regulation of gene expression epigeneticGO:0045814150.304
posttranscriptional gene silencingGO:0016441100.277
Worm
male gamete generationGO:00482322850.274
dna methylation involved in gamete generationGO:0043046150.265
heterocycle catabolic processGO:00467002800.249
spermatogenesisGO:00072832840.244
digestive system developmentGO:00551232000.238
histone h4 acetylationGO:0043967100.229
aromatic compound catabolic processGO:00194392860.224
organic cyclic compound catabolic processGO:19013612950.223
histone h4 k20 methylationGO:003477080.221
nucleoside phosphate metabolic processGO:00067533380.218
purine ribonucleoside triphosphate metabolic processGO:00092052200.210
protein alkylationGO:0008213810.210
neurohypophysis developmentGO:002198520.208
glycosyl compound catabolic processGO:19016582060.207
purine ribonucleoside triphosphate catabolic processGO:00092071990.197
mrna catabolic processGO:0006402220.188
purine containing compound metabolic processGO:00725213110.182
epithelial cell developmentGO:00020641590.181
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.180
cellular nitrogen compound catabolic processGO:00442702800.174
embryonic placenta developmentGO:0001892980.173
rna catabolic processGO:0006401290.173
purine nucleotide metabolic processGO:00061633020.172
regulation of transcription during meiosisGO:005103710.165
male meiosis iGO:0007141160.143
mrna metabolic processGO:0016071840.141
nucleotide metabolic processGO:00091173320.140
intracellular steroid hormone receptor signaling pathwayGO:0030518290.138
posttranscriptional gene silencing by rnaGO:0035194100.137
Worm
chromatin mediated maintenance of transcriptionGO:004809620.132
intracellular receptor signaling pathwayGO:0030522740.130
learning or memoryGO:00076111480.130
maintenance of locationGO:0051235890.130
purine nucleoside triphosphate metabolic processGO:00091442260.127
nucleoside phosphate catabolic processGO:19012922220.126
peptidyl lysine modificationGO:0018205770.126
Human Worm Fly
nucleobase containing small molecule metabolic processGO:00550863520.125
nucleoside metabolic processGO:00091162460.120
purine containing compound catabolic processGO:00725232130.120
cell cycle checkpointGO:0000075470.115
nucleoside triphosphate metabolic processGO:00091412300.114
glycosyl compound metabolic processGO:19016572460.113
myeloid cell differentiationGO:00300992330.112
ribonucleotide catabolic processGO:00092612080.111
nuclear transcribed mrna catabolic processGO:0000956160.109
cognitionGO:00508901490.106
oogenesisGO:0048477560.105
dna modificationGO:0006304500.103
purine nucleotide catabolic processGO:00061952110.102
dna alkylationGO:0006305430.102
purine ribonucleoside metabolic processGO:00461282410.099
mitotic sister chromatid cohesionGO:000706410.095
nucleotide catabolic processGO:00091662170.094
negative regulation of synapse assemblyGO:005196430.089
purine nucleoside catabolic processGO:00061522050.089
peptidyl lysine acetylationGO:0018394450.085
regulation of response to drugGO:200102320.083
ribose phosphate metabolic processGO:00196932910.083
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.083
lateral line system developmentGO:004892510.082
purine nucleoside metabolic processGO:00422782410.082
ribonucleoside catabolic processGO:00424542060.080
atp catabolic processGO:0006200550.076
macromolecule deacylationGO:0098732370.075
regulation of synaptic growth at neuromuscular junctionGO:000858240.075
homeostasis of number of cellsGO:00488722100.075
purine ribonucleotide metabolic processGO:00091502900.070
regulation of mapk cascadeGO:00434082480.068
purine nucleoside triphosphate catabolic processGO:00091462030.068
nucleoside monophosphate metabolic processGO:0009123850.068
nuclear transcribed mrna poly a tail shorteningGO:000028970.068
inositol phosphate mediated signalingGO:0048016130.065
negative regulation of cell cycleGO:00457861230.065
ras protein signal transductionGO:0007265770.065
leukocyte mediated immunityGO:00024431740.065
ribonucleoside monophosphate metabolic processGO:0009161800.064
olfactory learningGO:000835520.063
epithalamus developmentGO:002153820.063
stem cell developmentGO:00488642190.062
regulation of jak stat cascadeGO:0046425340.062
erythrocyte differentiationGO:0030218880.062
ribonucleoside metabolic processGO:00091192450.060
cerebellar purkinje cell layer morphogenesisGO:0021692140.059
regulation of gtp catabolic processGO:00331241130.059
purine nucleoside monophosphate catabolic processGO:0009128580.057
blastocyst developmentGO:0001824800.057
histone acetylationGO:0016573410.056
cell differentiation in hindbrainGO:0021533240.056
carbohydrate derivative catabolic processGO:19011362310.056
cellular response to lipidGO:00713961450.055
establishment of synaptic vesicle localizationGO:0097480570.055
histone h3 k9 methylationGO:0051567170.054
Fly
gastrulationGO:00073691160.054
nucleoside triphosphate catabolic processGO:00091432050.054
synapse organizationGO:00508081250.052
cellular response to alcoholGO:0097306230.052
lateral inhibitionGO:004633110.051
physiological muscle hypertrophyGO:000329830.051
heart trabecula morphogenesisGO:0061384260.050
dna damage checkpointGO:0000077260.049
negative regulation of cell growth involved in cardiac muscle cell developmentGO:006105220.049
placenta developmentGO:00018901400.048
ribonucleoside triphosphate metabolic processGO:00091992200.048
cytoplasmic transportGO:00164822340.048
syncytium formation by plasma membrane fusionGO:0000768420.047
chromatin remodelingGO:0006338320.047
myeloid leukocyte mediated immunityGO:0002444420.047
protein dna complex subunit organizationGO:0071824280.046
optic nerve formationGO:002163410.045
sister chromatid cohesionGO:0007062120.044
regulation of cell motilityGO:20001452360.042
stem cell fate specificationGO:004886630.042
ribonucleotide metabolic processGO:00092592910.042
endoderm formationGO:0001706200.041
peptidyl amino acid modificationGO:00181933360.041
Human Worm Fly
embryonic hemopoiesisGO:0035162230.041
digestive tract developmentGO:00485651900.041
negative regulation of bmp signaling pathwayGO:0030514350.041
endoderm developmentGO:0007492450.041
regulation of posttranscriptional gene silencingGO:006014750.040
external genitalia morphogenesisGO:003526110.040
macromolecule catabolic processGO:00090572810.039
physiological cardiac muscle hypertrophyGO:000330130.039
organelle assemblyGO:00709251770.039
regulation of defense responseGO:00313472330.038
gland developmentGO:00487323300.038
maintenance of chromatin silencingGO:000634420.037
synaptic vesicle localizationGO:0097479590.037
digestive tract morphogenesisGO:00485461470.037
endocytosisGO:00068971680.037
Worm
purine nucleoside monophosphate metabolic processGO:0009126810.037
regulation of dna damage checkpointGO:200000130.037
ribonucleoside monophosphate catabolic processGO:0009158570.036
proprioceptionGO:001923040.036
cell growth involved in cardiac muscle cell developmentGO:006104930.036
dna packagingGO:0006323300.036
regulation of bmp signaling pathwayGO:0030510600.035
regulation of gene silencing by rnaGO:006096650.035
sensory perception of soundGO:0007605970.035
jak stat cascadeGO:0007259420.035
development of primary sexual characteristicsGO:00451371430.034
Worm
organophosphate catabolic processGO:00464342320.034
negative regulation of mapk cascadeGO:0043409650.034
response to organic cyclic compoundGO:00140701980.034
purine ribonucleoside monophosphate catabolic processGO:0009169570.034
somitogenesisGO:0001756690.033
positive regulation of mapk cascadeGO:00434101700.033
purine ribonucleoside monophosphate metabolic processGO:0009167800.033
dna integrity checkpointGO:0031570280.032
histone h3 k9 trimethylationGO:003612460.032
Fly
response to nutrient levelsGO:00316671090.032
sensory system developmentGO:004888030.032
chromatin assemblyGO:0031497130.031
sensory perception of mechanical stimulusGO:00509541070.031
hepaticobiliary system developmentGO:0061008670.031
regulation of mrna 3 end processingGO:003144060.031
carbon catabolite regulation of transcription from rna polymerase ii promoterGO:000042940.031
positive regulation of mrna 3 end processingGO:003144250.031
regulation of cellular response to stressGO:00801351590.030
regionalizationGO:00030023370.030
protein acylationGO:0043543640.030
organelle localizationGO:00516401790.030
germ cell developmentGO:00072811850.030
formation of primary germ layerGO:0001704770.029
apical constrictionGO:000338340.029
dna hypermethylationGO:004402630.029
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.029
male gonad developmentGO:0008584880.029
nucleocytoplasmic transportGO:00069131390.029
aortic valve morphogenesisGO:000318040.029
cellular response to organic cyclic compoundGO:0071407870.029
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103060.028
respiratory tube developmentGO:00303231670.028
regulation of cytoplasmic transportGO:19036491120.028
small gtpase mediated signal transductionGO:0007264970.028
response to retinoic acidGO:0032526560.027
regulation of purine nucleotide catabolic processGO:00331211220.027
regulation of cellular component sizeGO:00325351210.027
female sex differentiationGO:0046660840.027
positive regulation of organelle organizationGO:00106381280.027
Fly
negative regulation of nfat protein import into nucleusGO:005153430.027
histone h4 k16 acetylationGO:004398430.026
male sex differentiationGO:00466611090.026
regulation of organ growthGO:0046620610.026
ventricular cardiac myofibril assemblyGO:005500530.026
regulation of histone modificationGO:0031056560.026
Fly
negative regulation of protein metabolic processGO:00512482820.026
regulation of mrna processingGO:0050684410.026
regulation of mrna catabolic processGO:006101360.026
nucleoside monophosphate catabolic processGO:0009125590.026
positive regulation of apoptotic processGO:00430652170.026
positive regulation of cellular amine metabolic processGO:003324050.026
nucleoside catabolic processGO:00091642060.025
cerebellar purkinje cell layer developmentGO:0021680260.025
response to inorganic substanceGO:0010035960.025
negative regulation of cell cycle phase transitionGO:1901988480.025
protein targetingGO:00066051430.025
camera type eye developmentGO:00430102660.025
labyrinthine layer blood vessel developmentGO:0060716210.025
neuron projection guidanceGO:00974851410.024
nuclear divisionGO:00002801580.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.024
chemotaxisGO:00069352470.024
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.024
cellular amino acid metabolic processGO:00065201030.024
histone h3 k14 acetylationGO:004415430.024
habenula developmentGO:002198620.024
microtubule cytoskeleton organizationGO:00002261570.024
positive regulation of chromosome organizationGO:2001252330.023
Fly
positive regulation of cellular component biogenesisGO:0044089940.023
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.023
regulation of neuron differentiationGO:00456642810.023
metencephalon developmentGO:0022037890.022
protein deacetylationGO:0006476320.022
histone deacetylationGO:0016575260.022
nucleosome positioningGO:001658440.022
atp metabolic processGO:0046034750.022
exocytosisGO:00068871210.022
head morphogenesisGO:0060323340.022
molting cycleGO:0042303900.022
regulation of transcription by chromatin organizationGO:003440100.021
intracellular protein transportGO:00068862040.021
nuclear exportGO:0051168340.021
regulation of vesicle mediated transportGO:00606271390.021
multicellular organism growthGO:00352641610.021
regulation of transcription from rna polymerase ii promoter by galactoseGO:000043110.021
establishment of organelle localizationGO:00516561220.021
regulation of mitotic cell cycle phase transitionGO:1901990730.021
positive regulation of muscle cell apoptotic processGO:001066160.021
mammary gland epithelium developmentGO:0061180650.020
axon guidanceGO:00074111410.020
oxidation reduction processGO:00551143420.020
ear morphogenesisGO:00424711180.020
regulation of organelle organizationGO:00330432890.020
Fly
internal protein amino acid acetylationGO:0006475420.020
multinuclear osteoclast differentiationGO:007267440.020
positive regulation of protein bindingGO:0032092290.020
morphogenesis of embryonic epitheliumGO:00163311590.020
regulation of viral transcriptionGO:004678230.019
erythrocyte maturationGO:004324960.019
microtubule based processGO:00070172360.019
nucleic acid phosphodiester bond hydrolysisGO:0090305490.019
mitotic sister chromatid segregationGO:0000070140.019
organophosphate biosynthetic processGO:00904071220.019
cellular response to nutrient levelsGO:0031669640.019
sister chromatid segregationGO:0000819200.019
mitotic cell cycleGO:00002781950.018
heterochromatin organizationGO:007082840.018
dna templated transcription initiationGO:0006352130.018
internal peptidyl lysine acetylationGO:0018393420.018
labyrinthine layer developmentGO:0060711490.018
regulation of kinase activityGO:00435492490.018
chromatin assembly or disassemblyGO:0006333160.018
development of primary male sexual characteristicsGO:0046546880.018
cytoplasmic mrna processing body assemblyGO:003396260.018
negative regulation of mesenchymal cell proliferationGO:007220130.018
histone h4 deacetylationGO:007093340.018
cellular response to sterolGO:003631520.018
protein deacylationGO:0035601360.018
mapk cascadeGO:00001652810.018
mrna processingGO:0006397630.018
plasma membrane organizationGO:0007009900.018
regulation of ras protein signal transductionGO:00465781140.017
cellularizationGO:000734910.017
histone h4 k12 acetylationGO:004398320.017
negative regulation of phosphorylationGO:00423261660.017
regulation of gene silencing by mirnaGO:006096440.017
branchiomotor neuron axon guidanceGO:002178570.017
rho protein signal transductionGO:0007266320.017
female gamete generationGO:0007292740.017
mitotic g2 dna damage checkpointGO:000709580.016
respiratory system developmentGO:00605411900.016
gonad developmentGO:00084061410.016
Worm
face developmentGO:0060324380.016
stem cell maintenanceGO:00198271300.016
cranial nerve developmentGO:0021545410.016
positive regulation of growthGO:00459271040.016
regulation of rna splicingGO:0043484370.016
defecationGO:003042110.016
regulation of wnt signaling pathway planar cell polarity pathwayGO:2000095100.016
myeloid leukocyte activationGO:0002274830.016
regulation of innate immune responseGO:0045088910.016
feeding behaviorGO:0007631620.016
phosphatidylinositol phosphorylationGO:0046854230.016
cell substrate adhesionGO:00315891300.016
branching involved in mammary gland duct morphogenesisGO:0060444270.016
regulation of secretionGO:00510462740.016
striated muscle adaptationGO:0014888260.016
regulation of cellular catabolic processGO:00313292420.016
organelle fissionGO:00482851700.016
regulation of notch signaling pathwayGO:0008593350.016
dendrite developmentGO:00163581150.016
glycerophospholipid metabolic processGO:0006650710.016
cell type specific apoptotic processGO:00972852680.016
somite developmentGO:0061053810.015
regulation of gene expression by genetic imprintingGO:0006349150.015
phagocytosisGO:0006909660.015
cerebellum morphogenesisGO:0021587420.015
regulation of microvillus assemblyGO:003253430.015
cardiac muscle hypertrophyGO:0003300230.015
axonogenesisGO:00074092740.015
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.015
regulation of hippo signalingGO:003533010.015
regulation of rna export from nucleusGO:004683140.015
clara cell differentiationGO:006048640.015
regulation of feeding behaviorGO:006025930.015
muscle hypertrophyGO:0014896240.014
associative learningGO:0008306610.014
regulation of alternative mrna splicing via spliceosomeGO:000038180.014
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.014
leukocyte differentiationGO:00025213420.014
mammary gland morphogenesisGO:0060443540.014
spleen developmentGO:0048536390.014
positive regulation of histone h3 k9 methylationGO:005157440.014
Fly
synaptic transmissionGO:00072683290.014
positive regulation of mrna processingGO:0050685160.014
embryonic limb morphogenesisGO:00303261260.014
regulation of muscle cell apoptotic processGO:0010660170.014
metanephric loop of henle developmentGO:007223640.014
positive regulation of cell cycle processGO:0090068610.014
divalent inorganic cation homeostasisGO:00725071380.014
hindbrain morphogenesisGO:0021575460.013
dna repairGO:00062811070.013
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015350.013
negative regulation of mitotic cell cycle phase transitionGO:1901991450.013
rna interferenceGO:001624620.013
Worm
n terminal protein amino acid modificationGO:003136560.013
regulation of embryonic developmentGO:0045995710.013
negative regulation of pancreatic juice secretionGO:009018830.013
intracellular mrna localizationGO:000829840.013
vesicle localizationGO:0051648860.013
myotube differentiationGO:00149021050.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
face morphogenesisGO:0060325290.013
positive regulation of protein modification processGO:00314012990.013
Fly
cardiac muscle cell differentiationGO:0055007690.013
regulation of cell cycleGO:00517262810.013
blastocyst growthGO:0001832230.013
epithelial cell proliferationGO:00506731740.013
rna processingGO:00063961050.013
regulation of establishment of protein localizationGO:00702011810.013
symbiosis encompassing mutualism through parasitismGO:0044403830.013
negative regulation of chromatin silencingGO:003193610.013
muscle system processGO:00030121410.013
positive regulation of cellular catabolic processGO:00313311480.012
positive regulation of cardiac muscle cell proliferationGO:0060045150.012
positive regulation of transcription by galactoseGO:000041110.012
positive regulation of cell deathGO:00109422240.012
heterochromatin organization involved in chromatin silencingGO:007086810.012
synaptic vesicle transportGO:0048489570.012
carbohydrate metabolic processGO:00059752300.012
positive regulation of necrotic cell deathGO:001094010.012
neuromuscular processGO:0050905990.012
cell cycle switching mitotic to meiotic cell cycleGO:005172810.012
heart morphogenesisGO:00030071780.012
endomembrane system organizationGO:00102561470.012
embryonic appendage morphogenesisGO:00351131260.012
response to alcoholGO:0097305480.012
negative regulation of germinal center formationGO:000263520.012
cellular response to biotic stimulusGO:0071216920.012
mesenchyme developmentGO:00604851520.012
positive regulation of glycogen starch synthase activityGO:200046740.012
tissue migrationGO:0090130680.012
gall bladder developmentGO:006101020.012
cellular response to x rayGO:007148120.012
cerebellar cortex developmentGO:0021695480.012
cell cycle switchingGO:006018410.012
organ growthGO:00352651170.011
negative regulation of cellular protein metabolic processGO:00322692470.011
sertoli cell developmentGO:0060009150.011
cellular metal ion homeostasisGO:00068751510.011
regulation of mesenchymal cell proliferation involved in lung developmentGO:200079020.011
regulation of nucleotide catabolic processGO:00308111220.011
genitalia developmentGO:0048806370.011
response to estrogenGO:0043627240.011
cerebellar purkinje cell layer formationGO:0021694130.011
positive regulation of mitotic cell cycleGO:0045931410.011
regulation of calcium ion transport into cytosolGO:0010522310.011
regulation of system processGO:00440572000.011
mesodermal to mesenchymal transition involved in gastrulationGO:006080910.011
neutrophil mediated immunityGO:0002446190.011
regulation of cytoskeleton organizationGO:00514931220.011
positive regulation of notch signaling pathwayGO:0045747180.011
blood vessel morphogenesisGO:00485142850.011
actin filament organizationGO:00070151130.011
negative regulation of cell cycle processGO:0010948690.011
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.011
negative regulation of mesenchymal cell proliferation involved in lung developmentGO:200079120.011
germ line stem cell divisionGO:004207820.011
regulation of mitotic cell cycleGO:00073461260.011
positive regulation of programmed cell deathGO:00430682180.011
positive regulation of ras gtpase activityGO:0032320650.011
regulation of protein deacetylationGO:0090311170.011
regulation of rho protein signal transductionGO:0035023710.011
positive regulation of cell cycleGO:0045787920.010
sequestering of metal ionGO:0051238190.010
actin polymerization or depolymerizationGO:0008154540.010
regulation of cellular amino acid metabolic processGO:000652150.010
cerebellar cortex morphogenesisGO:0021696320.010
mitotic cell cycle processGO:19030471590.010
negative regulation of jak stat cascadeGO:004642670.010
negative regulation of phosphorus metabolic processGO:00105631840.010
innate immune responseGO:00450871570.010
learningGO:0007612980.010
inner cell mass cell fate commitmentGO:000182720.010
ectoderm formationGO:000170530.010
regulation of hydrolase activityGO:00513362460.010
regulation of meiotic cell cycleGO:0051445340.010
multi multicellular organism processGO:00447061090.010
negative regulation of humoral immune response mediated by circulating immunoglobulinGO:000292430.010
meiotic cell cycleGO:00513211220.010
negative regulation of defense responseGO:0031348770.010

Mll3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
long qt syndromeDOID:284300.034
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
neuropathyDOID:87000.017
neuromuscular diseaseDOID:44000.017
charcot marie tooth diseaseDOID:1059500.012
charcot marie tooth disease type 2DOID:005053900.010