| chromatin modification | GO:0016568 | 187 | 0.225 | |
| dna repair | GO:0006281 | 107 | 0.201 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.182 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.176 | |
| histone modification | GO:0016570 | 159 | 0.163 | |
| amine metabolic process | GO:0009308 | 45 | 0.155 | |
| chromatin organization | GO:0006325 | 206 | 0.154 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.126 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.125 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.125 | |
| histone methylation | GO:0016571 | 71 | 0.118 | |
| dna metabolic process | GO:0006259 | 303 | 0.103 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.096 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.095 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.085 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.084 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.081 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.073 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.072 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.069 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.060 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.059 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.056 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.056 | |
| histone h4 k16 acetylation | GO:0043984 | 3 | 0.056 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.056 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.052 | |
| peptidyl lysine methylation | GO:0018022 | 29 | 0.050 | |
| mrna processing | GO:0006397 | 63 | 0.049 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.047 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.047 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.047 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.046 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.044 | |
| intracellular protein transport | GO:0006886 | 204 | 0.044 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.043 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.041 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.041 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.041 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.040 | |
| protein acylation | GO:0043543 | 64 | 0.039 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.039 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.038 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.038 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.037 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.037 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.037 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.037 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.037 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.036 | |
| regulation of histone modification | GO:0031056 | 56 | 0.036 | |
| germ cell development | GO:0007281 | 185 | 0.036 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.036 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.036 | |
| macromolecule methylation | GO:0043414 | 120 | 0.035 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.035 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.035 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.034 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.034 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.033 | |
| double strand break repair | GO:0006302 | 48 | 0.032 | |
| cellular homeostasis | GO:0019725 | 240 | 0.032 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.031 | |
| regionalization | GO:0003002 | 337 | 0.031 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.031 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.030 | |
| compound eye development | GO:0048749 | 1 | 0.030 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.030 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.029 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.029 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.029 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.029 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.029 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.029 | |
| rna interference | GO:0016246 | 2 | 0.029 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.029 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.028 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.028 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.028 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.028 | |
| regulation of histone methylation | GO:0031060 | 30 | 0.028 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.027 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.027 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.027 | |
| cell fate commitment | GO:0045165 | 210 | 0.027 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.026 | |
| primary mirna processing | GO:0031053 | 1 | 0.026 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.026 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.025 | |
| membrane organization | GO:0061024 | 245 | 0.025 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.025 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.025 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.024 | |
| regulation of cell motility | GO:2000145 | 236 | 0.023 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.023 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.023 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.023 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.023 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.022 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.022 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.022 | |
| immune effector process | GO:0002252 | 321 | 0.022 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.022 | |
| regulation of cell migration | GO:0030334 | 219 | 0.021 | |
| protein localization to membrane | GO:0072657 | 108 | 0.021 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.021 | |
| mrna metabolic process | GO:0016071 | 84 | 0.021 | |
| gene silencing by mirna | GO:0035195 | 10 | 0.021 | |
| multicellular organism growth | GO:0035264 | 161 | 0.020 | |
| innate immune response | GO:0045087 | 157 | 0.020 | |
| glucose homeostasis | GO:0042593 | 128 | 0.020 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.020 | |
| protein localization to organelle | GO:0033365 | 185 | 0.020 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.020 | |
| cytokine production | GO:0001816 | 319 | 0.020 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.020 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.020 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.020 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.019 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.019 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.019 | |
| lipid localization | GO:0010876 | 126 | 0.019 | |
| gene silencing by rna | GO:0031047 | 19 | 0.019 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 58 | 0.019 | |
| gland development | GO:0048732 | 330 | 0.019 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.019 | |
| synaptic transmission | GO:0007268 | 329 | 0.019 | |
| protein alkylation | GO:0008213 | 81 | 0.019 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.018 | |
| rac protein signal transduction | GO:0016601 | 13 | 0.018 | |
| cell adhesion | GO:0007155 | 329 | 0.018 | |
| neural tube formation | GO:0001841 | 108 | 0.018 | |
| cell growth | GO:0016049 | 130 | 0.018 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.018 | |
| gtp catabolic process | GO:0006184 | 143 | 0.018 | |
| ear development | GO:0043583 | 200 | 0.018 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.018 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.017 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.017 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.017 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.017 | |
| dna recombination | GO:0006310 | 92 | 0.017 | |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.017 | |
| transcription from rna polymerase iii promoter | GO:0006383 | 3 | 0.016 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.016 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.016 | |
| epithalamus development | GO:0021538 | 2 | 0.016 | |
| gtp metabolic process | GO:0046039 | 144 | 0.016 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.016 | |
| positive regulation of histone modification | GO:0031058 | 28 | 0.016 | |
| negative regulation of multi organism process | GO:0043901 | 68 | 0.016 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.016 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.016 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.016 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.016 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.016 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.016 | |
| posttranslational protein targeting to membrane | GO:0006620 | 2 | 0.015 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.015 | |
| telomere capping | GO:0016233 | 4 | 0.015 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.015 | |
| histone h3 k4 trimethylation | GO:0080182 | 5 | 0.015 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.015 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.015 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.015 | |
| maintenance of location | GO:0051235 | 89 | 0.015 | |
| skeletal system development | GO:0001501 | 356 | 0.015 | |
| protein o linked glycosylation | GO:0006493 | 16 | 0.015 | |
| blastocyst development | GO:0001824 | 80 | 0.014 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.014 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.014 | |
| nucleobase containing compound transport | GO:0015931 | 27 | 0.014 | |
| regulation of cell size | GO:0008361 | 72 | 0.014 | |
| wound healing | GO:0042060 | 157 | 0.014 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.014 | |
| regulation of transcription from rna polymerase iii promoter | GO:0006359 | 2 | 0.014 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.014 | |
| carbohydrate biosynthetic process | GO:0016051 | 74 | 0.014 | |
| action potential | GO:0001508 | 78 | 0.014 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.014 | |
| organelle localization | GO:0051640 | 179 | 0.014 | |
| muscle tissue development | GO:0060537 | 308 | 0.014 | |
| protein targeting | GO:0006605 | 143 | 0.014 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.013 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.013 | |
| microtubule based process | GO:0007017 | 236 | 0.013 | |
| positive regulation of histone methylation | GO:0031062 | 16 | 0.013 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.013 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.013 | |
| dna methylation involved in gamete generation | GO:0043046 | 15 | 0.013 | |
| glucose metabolic process | GO:0006006 | 92 | 0.013 | |
| positive regulation of neuron projection development | GO:0010976 | 79 | 0.013 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 2 | 0.013 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.013 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.013 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.013 | |
| neural tube development | GO:0021915 | 160 | 0.013 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.013 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.013 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.013 | |
| developmental cell growth | GO:0048588 | 84 | 0.013 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.013 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.013 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.013 | |
| protein maturation | GO:0051604 | 176 | 0.012 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.012 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.012 | |
| humoral immune response | GO:0006959 | 57 | 0.012 | |
| hexose metabolic process | GO:0019318 | 98 | 0.012 | |
| internal protein amino acid acetylation | GO:0006475 | 42 | 0.012 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.012 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.012 | |
| positive regulation of gene silencing by mirna | GO:2000637 | 1 | 0.012 | |
| histone acetylation | GO:0016573 | 41 | 0.012 | |
| segmentation | GO:0035282 | 93 | 0.012 | |
| adult locomotory behavior | GO:0008344 | 91 | 0.012 | |
| pyruvate metabolic process | GO:0006090 | 28 | 0.012 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.012 | |
| heart morphogenesis | GO:0003007 | 178 | 0.012 | |
| negative regulation of protein depolymerization | GO:1901880 | 21 | 0.012 | |
| habenula development | GO:0021986 | 2 | 0.012 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.012 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.012 | |
| response to insulin | GO:0032868 | 100 | 0.012 | |
| response to nutrient levels | GO:0031667 | 109 | 0.012 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.012 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.011 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.011 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.011 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.011 | |
| regulation of carbohydrate biosynthetic process | GO:0043255 | 40 | 0.011 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.011 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.011 | |
| axonogenesis | GO:0007409 | 274 | 0.011 | |
| chemotaxis | GO:0006935 | 247 | 0.011 | |
| telomere maintenance | GO:0000723 | 19 | 0.011 | |
| regulation of cell growth | GO:0001558 | 91 | 0.011 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.011 | |
| protein homotrimerization | GO:0070207 | 4 | 0.011 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.011 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.011 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.011 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.011 | |
| methylation | GO:0032259 | 134 | 0.011 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.011 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.011 | |
| regulation of transcription during meiosis | GO:0051037 | 1 | 0.011 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.011 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.011 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.011 | |
| somatic diversification of immune receptors | GO:0002200 | 53 | 0.011 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.011 | |
| lateral inhibition | GO:0046331 | 1 | 0.011 | |
| protein ubiquitination | GO:0016567 | 171 | 0.011 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.011 | |
| somatic diversification of immune receptors via germline recombination within a single locus | GO:0002562 | 51 | 0.010 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.010 | |
| rna processing | GO:0006396 | 105 | 0.010 | |
| cation transport | GO:0006812 | 399 | 0.010 | |
| regulation of protein localization | GO:0032880 | 231 | 0.010 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.010 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.010 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.010 | |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.010 | |
| glucosamine containing compound metabolic process | GO:1901071 | 3 | 0.010 | |
| regulation of defense response | GO:0031347 | 233 | 0.010 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.010 | |
| cell recognition | GO:0008037 | 83 | 0.010 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.010 | |
| regulation of interleukin 1 alpha secretion | GO:0050705 | 3 | 0.010 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.010 | |