Mus musculus

17 known processes

Nek4

NIMA (never in mitosis gene a)-related expressed kinase 4

Nek4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cilium morphogenesisGO:00602711020.318
cilium assemblyGO:0042384810.260
cellular component assembly involved in morphogenesisGO:00109271390.116
cellular response to dna damage stimulusGO:00069742070.080
Human
organelle assemblyGO:00709251770.080
dna repairGO:00062811070.064
positive regulation of cellular amino acid metabolic processGO:004576430.056
intraciliary transportGO:004207390.051
cellular amino acid metabolic processGO:00065201030.047
microtubule based processGO:00070172360.045
cellular ketone metabolic processGO:0042180840.044
regulation of cellular amino acid metabolic processGO:000652150.044
cellular amine metabolic processGO:0044106440.044
microtubule based movementGO:0007018840.041
dna metabolic processGO:00062593030.041
regulation of organelle organizationGO:00330432890.038
organelle fissionGO:00482851700.036
regulation of cellular ketone metabolic processGO:0010565660.035
regulation of cellular amine metabolic processGO:0033238200.035
ribose phosphate metabolic processGO:00196932910.034
apoptotic signaling pathwayGO:00971903060.033
cellular nitrogen compound catabolic processGO:00442702800.033
positive regulation of cellular amine metabolic processGO:003324050.032
smoothened signaling pathwayGO:00072241050.032
organonitrogen compound catabolic processGO:19015652640.032
nuclear divisionGO:00002801580.031
ribonucleotide metabolic processGO:00092592910.030
regulation of cellular component biogenesisGO:00440871810.029
aromatic compound catabolic processGO:00194392860.029
nucleobase containing small molecule metabolic processGO:00550863520.027
purine containing compound metabolic processGO:00725213110.027
heterocycle catabolic processGO:00467002800.027
purine nucleotide metabolic processGO:00061633020.027
small gtpase mediated signal transductionGO:0007264970.027
camera type eye developmentGO:00430102660.027
cytoskeleton dependent intracellular transportGO:0030705500.027
ribonucleoside metabolic processGO:00091192450.027
male gamete generationGO:00482322850.027
amine metabolic processGO:0009308450.027
membrane organizationGO:00610242450.026
nucleotide metabolic processGO:00091173320.026
intraciliary retrograde transportGO:003572130.025
methylationGO:00322591340.024
nucleoside phosphate metabolic processGO:00067533380.024
chromatin organizationGO:00063252060.024
purine nucleoside metabolic processGO:00422782410.023
intracellular protein transportGO:00068862040.022
purine ribonucleotide catabolic processGO:00091542080.022
meiotic nuclear divisionGO:00071261150.022
sensory organ morphogenesisGO:00905962420.022
neural tube developmentGO:00219151600.021
nucleoside triphosphate catabolic processGO:00091432050.021
ribonucleoside triphosphate catabolic processGO:00092031990.021
organophosphate catabolic processGO:00464342320.021
ribonucleoside catabolic processGO:00424542060.021
glycosyl compound catabolic processGO:19016582060.021
purine ribonucleotide metabolic processGO:00091502900.021
ras protein signal transductionGO:0007265770.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
nucleoside catabolic processGO:00091642060.021
glycosyl compound metabolic processGO:19016572460.020
regulation of cilium assemblyGO:190201770.020
positive regulation of protein modification processGO:00314012990.020
fat cell differentiationGO:00454441600.020
nucleoside metabolic processGO:00091162460.020
purine containing compound catabolic processGO:00725232130.020
macromolecule catabolic processGO:00090572810.020
protein localization to organelleGO:00333651850.020
negative regulation of cellular component organizationGO:00511291940.019
cellular macromolecule catabolic processGO:00442652060.019
organic cyclic compound catabolic processGO:19013612950.019
carbohydrate derivative catabolic processGO:19011362310.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
peptidyl amino acid modificationGO:00181933360.019
purine nucleotide catabolic processGO:00061952110.019
skin developmentGO:00435882200.019
limb developmentGO:00601731660.019
skeletal system developmentGO:00015013560.018
chromatin modificationGO:00165681870.018
protein maturationGO:00516041760.018
anatomical structure homeostasisGO:00602491450.018
regionalizationGO:00030023370.018
nucleotide catabolic processGO:00091662170.018
organelle localizationGO:00516401790.018
rna processingGO:00063961050.018
mitotic cell cycleGO:00002781950.017
Human
purine ribonucleoside metabolic processGO:00461282410.017
protein modification by small protein conjugationGO:00324461870.017
limb morphogenesisGO:00351081490.017
nucleoside triphosphate metabolic processGO:00091412300.017
muscle tissue developmentGO:00605373080.017
microtubule based transportGO:0010970500.017
nucleoside phosphate catabolic processGO:19012922220.017
positive regulation of organelle organizationGO:00106381280.017
ribonucleotide catabolic processGO:00092612080.017
regulation of cell activationGO:00508652890.017
purine ribonucleoside catabolic processGO:00461302050.017
cell type specific apoptotic processGO:00972852680.017
embryonic organ morphogenesisGO:00485622760.017
regulation of protein localizationGO:00328802310.017
ear developmentGO:00435832000.016
purine nucleoside catabolic processGO:00061522050.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
epithelial tube formationGO:00721751300.016
microtubule cytoskeleton organizationGO:00002261570.016
appendage morphogenesisGO:00351071490.016
cellular homeostasisGO:00197252400.016
negative regulation of cell proliferationGO:00082852960.016
regulation of smoothened signaling pathwayGO:0008589580.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
retina development in camera type eyeGO:00600411190.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
spermatid differentiationGO:00485151150.015
response to radiationGO:00093141650.015
fertilizationGO:00095661270.015
cellular protein complex assemblyGO:00436231160.015
homeostasis of number of cellsGO:00488722100.015
spermatogenesisGO:00072832840.015
protein localization to membraneGO:00726571080.015
male meiosisGO:0007140370.015
macromolecule methylationGO:00434141200.015
embryonic appendage morphogenesisGO:00351131260.015
leukocyte differentiationGO:00025213420.015
regulation of cell cycleGO:00517262810.015
epithelial tube morphogenesisGO:00605623030.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
regulation of cell motilityGO:20001452360.015
multicellular organismal homeostasisGO:00488711640.014
myeloid cell differentiationGO:00300992330.014
immune effector processGO:00022523210.014
cellular lipid metabolic processGO:00442553230.014
transmembrane transportGO:00550854120.014
regulation of homeostatic processGO:00328441820.014
histone modificationGO:00165701590.014
modification dependent protein catabolic processGO:00199411330.014
appendage developmentGO:00487361660.014
tube formationGO:00351481400.014
regulation of establishment of protein localizationGO:00702011810.014
meiotic cell cycleGO:00513211220.014
maintenance of locationGO:0051235890.014
regulation of nucleotide metabolic processGO:00061401690.014
regulation of cellular catabolic processGO:00313292420.014
photoreceptor cell differentiationGO:0046530520.014
spermatid developmentGO:00072861080.014
mitotic cell cycle processGO:19030471590.014
epidermis developmentGO:00085441870.014
cellular response to hormone stimulusGO:00328701500.014
skeletal muscle organ developmentGO:00605381630.014
lymphocyte differentiationGO:00300982420.014
protein ubiquitinationGO:00165671710.014
neural tube formationGO:00018411080.014
germ cell developmentGO:00072811850.014
dephosphorylationGO:00163111290.013
epithelial cell proliferationGO:00506731740.013
embryonic limb morphogenesisGO:00303261260.013
regulation of cell cycle processGO:00105641600.013
morphogenesis of embryonic epitheliumGO:00163311590.013
endomembrane system organizationGO:00102561470.013
regulation of intracellular transportGO:00323861590.013
protein processingGO:00164851630.013
negative regulation of cellular protein metabolic processGO:00322692470.013
response to organonitrogen compoundGO:00102432460.013
protein modification by small protein conjugation or removalGO:00706472070.013
tube closureGO:0060606910.013
cellular protein catabolic processGO:00442571550.013
meiotic cell cycle processGO:1903046770.013
embryonic epithelial tube formationGO:00018381300.013
lipid biosynthetic processGO:00086101790.013
multicellular organism growthGO:00352641610.013
meiosis iGO:0007127600.012
skeletal system morphogenesisGO:00487052030.012
covalent chromatin modificationGO:00165691630.012
striated muscle tissue developmentGO:00147062930.012
negative regulation of molecular functionGO:00440922580.012
regulation of leukocyte differentiationGO:19021051590.012
muscle cell differentiationGO:00426922610.012
Mouse
regulation of proteolysisGO:00301621640.012
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.012
regulation of apoptotic signaling pathwayGO:20012331970.012
cellular response to organonitrogen compoundGO:00714171450.012
t cell activationGO:00421102890.012
intracellular mrna localizationGO:000829840.012
male genitalia morphogenesisGO:004880840.012
embryonic digit morphogenesisGO:0042733560.012
chromosome organization involved in meiosisGO:0070192390.012
cellular response to growth factor stimulusGO:00713631970.012
cellular response to cytokine stimulusGO:00713451890.012
positive regulation of cellular catabolic processGO:00313311480.012
renal system developmentGO:00720012250.012
negative regulation of immune system processGO:00026832090.012
regulation of lymphocyte activationGO:00512492400.012
rho protein signal transductionGO:0007266320.012
regulation of anatomical structure sizeGO:00900661780.012
primary neural tube formationGO:0014020950.012
regulation of protein processingGO:0070613960.012
digestive system developmentGO:00551232000.012
sensory perceptionGO:00076002450.011
wnt signaling pathwayGO:00160551880.011
adult behaviorGO:00305341350.011
negative regulation of nervous system developmentGO:00519611560.011
regulation of cell adhesionGO:00301551540.011
regulation of chromosome organizationGO:0033044830.011
forebrain developmentGO:00309003020.011
cell divisionGO:00513011200.011
blastocyst developmentGO:0001824800.011
lateral inhibitionGO:004633110.011
positive regulation of cell activationGO:00508671580.011
axonogenesisGO:00074092740.011
negative regulation of cell developmentGO:00107211690.011
regulation of cytoskeleton organizationGO:00514931220.011
reactive oxygen species metabolic processGO:0072593840.011
glycerolipid metabolic processGO:00464861220.011
peptidyl lysine modificationGO:0018205770.011
regulation of protein maturationGO:1903317960.011
positive regulation of protein phosphorylationGO:00019342420.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
regulation of protein complex assemblyGO:0043254830.011
transmission of nerve impulseGO:0019226760.011
telencephalon developmentGO:00215371860.011
urogenital system developmentGO:00016552610.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
eye photoreceptor cell differentiationGO:0001754410.011
neuronal action potentialGO:0019228540.011
bone developmentGO:00603481200.011
protein catabolic processGO:00301632210.011
mrna metabolic processGO:0016071840.011
dna recombinationGO:0006310920.011
regulation of defense responseGO:00313472330.011
male anatomical structure morphogenesisGO:009059840.011
response to growth factorGO:00708481980.011
regulation of protein transportGO:00512231630.011
protein polymerizationGO:0051258570.011
carbohydrate metabolic processGO:00059752300.011
multicellular organismal signalingGO:0035637910.011
response to acid chemicalGO:00011011110.011
chromosome segregationGO:0007059480.011
protein localization to nucleusGO:00345041210.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
nucleus organizationGO:0006997450.011
regulation of epithelial cell proliferationGO:00506781410.011
establishment of protein localization to organelleGO:00725941180.011
inflammatory responseGO:00069542440.011
hindbrain developmentGO:00309021280.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
regulation of cell projection organizationGO:00313442060.010
regulation of membrane potentialGO:00423911920.010
tissue homeostasisGO:00018941150.010
positive regulation of lymphocyte activationGO:00512511400.010
ubiquitin dependent protein catabolic processGO:00065111290.010
nitrogen compound transportGO:00717052710.010
negative regulation of organelle organizationGO:0010639900.010
spindle assembly involved in mitosisGO:009030740.010
rac protein signal transductionGO:0016601130.010
sequestering of calcium ionGO:0051208180.010
developmental maturationGO:00217001930.010
microtubule cytoskeleton organization involved in mitosisGO:190285040.010
regulation of cell migrationGO:00303342190.010
regulation of transferase activityGO:00513382630.010
proteasomal protein catabolic processGO:0010498980.010
actin filament organizationGO:00070151130.010
cation transportGO:00068123990.010
regulation of hydrolase activityGO:00513362460.010
Mouse
photoreceptor cell developmentGO:0042461400.010

Nek4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
organ system cancerDOID:005068600.024
immune system diseaseDOID:291400.023
eye and adnexa diseaseDOID:149200.022
sensory system diseaseDOID:005015500.022
retinal diseaseDOID:567900.022
eye diseaseDOID:561400.022
hematopoietic system diseaseDOID:7400.020
retinal degenerationDOID:846600.016