Mus musculus

10 known processes

Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

(Aliases: D8Ertd790e,MGC189817,kat)

Nek1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ribonucleoside triphosphate metabolic processGO:00091992200.111
organophosphate catabolic processGO:00464342320.110
rho protein signal transductionGO:0007266320.108
nucleoside catabolic processGO:00091642060.090
cilium morphogenesisGO:00602711020.090
Human
nucleoside triphosphate metabolic processGO:00091412300.086
ribonucleoside catabolic processGO:00424542060.084
purine containing compound catabolic processGO:00725232130.084
ras protein signal transductionGO:0007265770.080
carbohydrate derivative catabolic processGO:19011362310.079
small gtpase mediated signal transductionGO:0007264970.079
purine ribonucleoside triphosphate metabolic processGO:00092052200.079
organonitrogen compound catabolic processGO:19015652640.077
heterocycle catabolic processGO:00467002800.076
purine nucleoside catabolic processGO:00061522050.075
purine nucleoside triphosphate metabolic processGO:00091442260.073
regulation of hydrolase activityGO:00513362460.072
nucleoside metabolic processGO:00091162460.072
purine ribonucleoside triphosphate catabolic processGO:00092071990.072
nucleoside triphosphate catabolic processGO:00091432050.071
cellular amine metabolic processGO:0044106440.070
nucleoside phosphate catabolic processGO:19012922220.070
organelle localizationGO:00516401790.070
organic cyclic compound catabolic processGO:19013612950.068
male gamete generationGO:00482322850.068
purine nucleotide catabolic processGO:00061952110.068
regulation of rho gtpase activityGO:0032319580.064
purine ribonucleoside metabolic processGO:00461282410.062
ribonucleoside triphosphate catabolic processGO:00092031990.061
purine ribonucleotide catabolic processGO:00091542080.060
cellular nitrogen compound catabolic processGO:00442702800.060
microtubule based processGO:00070172360.059
ribonucleotide metabolic processGO:00092592910.059
ribose phosphate metabolic processGO:00196932910.058
purine containing compound metabolic processGO:00725213110.058
aromatic compound catabolic processGO:00194392860.057
amine metabolic processGO:0009308450.056
nucleotide metabolic processGO:00091173320.056
axonogenesisGO:00074092740.055
glycosyl compound metabolic processGO:19016572460.054
purine nucleotide metabolic processGO:00061633020.052
regulation of protein localizationGO:00328802310.050
glycosyl compound catabolic processGO:19016582060.049
regulation of nucleoside metabolic processGO:00091181300.049
regulation of neuron projection developmentGO:00109751690.048
peptidyl amino acid modificationGO:00181933360.047
response to organonitrogen compoundGO:00102432460.046
ribonucleoside metabolic processGO:00091192450.046
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.045
regulation of cellular ketone metabolic processGO:0010565660.044
cellular amino acid metabolic processGO:00065201030.044
regulation of cellular component biogenesisGO:00440871810.044
microtubule based movementGO:0007018840.044
chemotaxisGO:00069352470.043
fertilizationGO:00095661270.043
purine nucleoside metabolic processGO:00422782410.043
nucleotide catabolic processGO:00091662170.042
guanosine containing compound metabolic processGO:19010681440.041
protein polymerizationGO:0051258570.041
regulation of cytoskeleton organizationGO:00514931220.041
purine nucleoside triphosphate catabolic processGO:00091462030.041
cellular response to dna damage stimulusGO:00069742070.040
regulation of cell projection organizationGO:00313442060.040
cellular lipid metabolic processGO:00442553230.040
regulation of organelle organizationGO:00330432890.040
meiotic cell cycleGO:00513211220.040
rac protein signal transductionGO:0016601130.039
spermatogenesisGO:00072832840.039
regulation of nucleotide catabolic processGO:00308111220.038
cellular ketone metabolic processGO:0042180840.038
camera type eye developmentGO:00430102660.038
purine ribonucleotide metabolic processGO:00091502900.038
regulation of cellular amine metabolic processGO:0033238200.038
protein catabolic processGO:00301632210.038
gtp catabolic processGO:00061841430.037
endomembrane system organizationGO:00102561470.036
apoptotic signaling pathwayGO:00971903060.036
negative regulation of protein metabolic processGO:00512482820.036
cellular protein complex assemblyGO:00436231160.036
positive regulation of cellular amino acid metabolic processGO:004576430.035
gland developmentGO:00487323300.034
organelle fissionGO:00482851700.034
regulation of purine nucleotide catabolic processGO:00331211220.034
regulation of cell morphogenesis involved in differentiationGO:00107691510.033
regulation of cellular catabolic processGO:00313292420.033
dna metabolic processGO:00062593030.032
establishment of organelle localizationGO:00516561220.032
regulation of cellular amino acid metabolic processGO:000652150.032
axon guidanceGO:00074111410.031
learning or memoryGO:00076111480.030
nucleobase containing small molecule metabolic processGO:00550863520.030
intrinsic apoptotic signaling pathwayGO:00971931320.030
purine ribonucleoside catabolic processGO:00461302050.030
nucleoside phosphate metabolic processGO:00067533380.030
immune effector processGO:00022523210.030
positive regulation of cellular amine metabolic processGO:003324050.029
wnt signaling pathwayGO:00160551880.029
modification dependent macromolecule catabolic processGO:00436321330.029
regulation of nucleotide metabolic processGO:00061401690.028
microtubule cytoskeleton organizationGO:00002261570.028
response to growth factorGO:00708481980.028
cytoskeleton dependent intracellular transportGO:0030705500.027
homeostasis of number of cellsGO:00488722100.027
regulation of mapk cascadeGO:00434082480.027
regulation of synaptic growth at neuromuscular junctionGO:000858240.027
cell type specific apoptotic processGO:00972852680.027
regulation of cell cycleGO:00517262810.027
negative regulation of synapse assemblyGO:005196430.026
transmembrane transportGO:00550854120.026
ubiquitin dependent protein catabolic processGO:00065111290.026
actin filament polymerizationGO:0030041440.026
gtp metabolic processGO:00460391440.026
inflammatory responseGO:00069542440.026
positive regulation of organelle organizationGO:00106381280.026
protein localization to organelleGO:00333651850.026
synapse organizationGO:00508081250.025
positive regulation of cellular catabolic processGO:00313311480.025
protein maturationGO:00516041760.025
regulation of apoptotic signaling pathwayGO:20012331970.025
leukocyte differentiationGO:00025213420.025
negative regulation of cellular protein metabolic processGO:00322692470.025
response to peptideGO:19016521360.025
nuclear divisionGO:00002801580.025
regulation of cellular component sizeGO:00325351210.025
macromolecule catabolic processGO:00090572810.025
positive regulation of protein modification processGO:00314012990.024
regulation of cell migrationGO:00303342190.024
myeloid cell differentiationGO:00300992330.024
positive regulation of mapk cascadeGO:00434101700.024
cellular homeostasisGO:00197252400.024
skeletal system developmentGO:00015013560.024
regulation of gtp catabolic processGO:00331241130.024
ion transmembrane transportGO:00342203610.024
mitotic cell cycleGO:00002781950.024
ephrin receptor signaling pathwayGO:0048013200.024
negative regulation of t helper 2 cell differentiationGO:004562940.024
regulation of ras protein signal transductionGO:00465781140.023
dna repairGO:00062811070.023
maintenance of locationGO:0051235890.023
blood vessel morphogenesisGO:00485142850.023
regulation of protein complex assemblyGO:0043254830.023
regulation of secretion by cellGO:19035302490.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.023
cell maturationGO:00484691270.023
sensory organ morphogenesisGO:00905962420.023
methylationGO:00322591340.023
developmental maturationGO:00217001930.022
positive regulation of protein phosphorylationGO:00019342420.022
meiotic nuclear divisionGO:00071261150.022
response to inorganic substanceGO:0010035960.022
striated muscle tissue developmentGO:00147062930.022
cation homeostasisGO:00550802120.022
spermatid differentiationGO:00485151150.022
multicellular organism growthGO:00352641610.022
skin developmentGO:00435882200.022
guanosine containing compound catabolic processGO:19010691440.022
regulation of cell cycle processGO:00105641600.021
regulation of actin filament based processGO:0032970990.021
protein modification by small protein conjugationGO:00324461870.021
regulation of membrane potentialGO:00423911920.021
cellular response to hormone stimulusGO:00328701500.021
negative regulation of molecular functionGO:00440922580.021
negative regulation of cellular amino acid metabolic processGO:004576300.021
divalent inorganic cation transportGO:00725111780.021
oxidation reduction processGO:00551143420.021
anatomical structure homeostasisGO:00602491450.021
t cell activationGO:00421102890.020
regulation of protein kinase activityGO:00458592320.020
dna dependent dna replication maintenance of fidelityGO:004500530.020
regulation of cell motilityGO:20001452360.020
mapk cascadeGO:00001652810.020
ribonucleotide catabolic processGO:00092612080.020
regulation of secretionGO:00510462740.020
regulation of neuron differentiationGO:00456642810.020
forebrain developmentGO:00309003020.020
sensory perceptionGO:00076002450.020
respiratory system developmentGO:00605411900.020
regulation of kinase activityGO:00435492490.020
regulation of cell activationGO:00508652890.019
response to peptide hormoneGO:00434341270.019
regulation of peptidase activityGO:0052547960.019
hematopoietic progenitor cell differentiationGO:00022441430.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
posttranscriptional regulation of gene expressionGO:00106081550.019
muscle tissue developmentGO:00605373080.019
negative regulation of nervous system developmentGO:00519611560.019
nucleoside monophosphate metabolic processGO:0009123850.019
actin filament based movementGO:0030048230.019
cytoplasmic transportGO:00164822340.019
epithelial cell proliferationGO:00506731740.019
regulation of homeostatic processGO:00328441820.018
protein ubiquitinationGO:00165671710.018
cell divisionGO:00513011200.018
gliogenesisGO:00420631410.018
regulation of vesicle mediated transportGO:00606271390.018
regulation of purine nucleotide metabolic processGO:19005421690.018
regulation of proteolysisGO:00301621640.018
positive regulation of protein kinase activityGO:00458601440.018
positive regulation of nervous system developmentGO:00519622210.018
regulation of rho protein signal transductionGO:0035023710.018
single organism cell adhesionGO:00986021560.018
regulation of establishment of protein localizationGO:00702011810.018
canonical wnt signaling pathwayGO:00600701300.018
response to acid chemicalGO:00011011110.018
spermatid developmentGO:00072861080.018
cell recognitionGO:0008037830.018
cation transportGO:00068123990.018
regionalizationGO:00030023370.018
actin cytoskeleton organizationGO:00300362200.018
cell growthGO:00160491300.018
neuron projection guidanceGO:00974851410.018
placenta developmentGO:00018901400.017
protein processingGO:00164851630.017
positive regulation of hydrolase activityGO:00513451480.017
intracellular protein transportGO:00068862040.017
modification dependent protein catabolic processGO:00199411330.017
single organismal cell cell adhesionGO:00163371310.017
epithelial cell developmentGO:00020641590.017
actin filament organizationGO:00070151130.017
cellular response to transforming growth factor beta stimulusGO:0071560880.017
peptidyl serine phosphorylationGO:0018105740.017
leukocyte migrationGO:00509001240.017
metal ion homeostasisGO:00550651890.017
regulation of ion transportGO:00432692150.017
ribonucleoside monophosphate metabolic processGO:0009161800.017
organelle assemblyGO:00709251770.016
Human
positive regulation of cellular component biogenesisGO:0044089940.016
lung developmentGO:00303241640.016
purine nucleoside monophosphate metabolic processGO:0009126810.016
extrinsic apoptotic signaling pathwayGO:00971911260.016
multicellular organismal signalingGO:0035637910.016
regulation of protein serine threonine kinase activityGO:00719001570.016
synaptic transmissionGO:00072683290.016
negative regulation of intracellular signal transductionGO:19025321670.016
embryonic placenta developmentGO:0001892980.016
response to insulinGO:00328681000.016
regulation of protein processingGO:0070613960.016
regulation of lymphocyte activationGO:00512492400.016
regulation of ras gtpase activityGO:0032318880.016
positive regulation of kinase activityGO:00336741550.016
cellular macromolecule catabolic processGO:00442652060.016
proteolysis involved in cellular protein catabolic processGO:00516031470.016
myeloid cell homeostasisGO:00022621140.016
b cell activationGO:00421131610.016
meiotic cell cycle processGO:1903046770.016
actin mediated cell contractionGO:0070252150.015
fat cell differentiationGO:00454441600.015
purine ribonucleoside monophosphate metabolic processGO:0009167800.015
retina development in camera type eyeGO:00600411190.015
regulation of rac gtpase activityGO:0032314130.015
cellular protein catabolic processGO:00442571550.015
negative regulation of cellular component organizationGO:00511291940.015
microtubule based transportGO:0010970500.015
regulation of transferase activityGO:00513382630.015
positive regulation of cytoskeleton organizationGO:0051495490.015
regulation of phospholipase c activityGO:190027430.015
regulation of wnt signaling pathwayGO:00301111230.015
cell adhesionGO:00071553290.015
multi multicellular organism processGO:00447061090.015
regulation of anatomical structure sizeGO:00900661780.015
carbohydrate homeostasisGO:00335001280.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
sequestering of calcium ionGO:0051208180.015
regulation of body fluid levelsGO:00508781620.014
regulation of lymphocyte differentiationGO:00456191070.014
defecationGO:003042110.014
endocytosisGO:00068971680.014
sensory perception of soundGO:0007605970.014
actin polymerization or depolymerizationGO:0008154540.014
cellularizationGO:000734910.014
negative regulation of cell proliferationGO:00082852960.014
regulation of cell adhesionGO:00301551540.014
dna recombinationGO:0006310920.014
neural tube developmentGO:00219151600.014
renal system developmentGO:00720012250.014
tissue homeostasisGO:00018941150.014
regulation of cysteine type endopeptidase activityGO:2000116650.014
protein localization to membraneGO:00726571080.014
positive regulation of transferase activityGO:00513471670.014
ear developmentGO:00435832000.014
adult behaviorGO:00305341350.014
inorganic cation transmembrane transportGO:00986622070.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
regulation of protein maturationGO:1903317960.014
cytokine productionGO:00018163190.014
leukocyte proliferationGO:00706611720.014
negative regulation of phosphate metabolic processGO:00459361840.014
positive regulation of nucleotide metabolic processGO:00459811140.014
inorganic ion transmembrane transportGO:00986602340.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
regulation of actin polymerization or depolymerizationGO:0008064450.014
regulation of canonical wnt signaling pathwayGO:0060828820.014
peptidyl serine modificationGO:0018209830.014
action potentialGO:0001508780.014
respiratory tube developmentGO:00303231670.014
kidney developmentGO:00018222130.014
organic hydroxy compound metabolic processGO:19016152030.013
regulation of leukocyte differentiationGO:19021051590.013
protein modification by small protein conjugation or removalGO:00706472070.013
developmental growth involved in morphogenesisGO:00605601380.013
dendritic spine organizationGO:0097061260.013
cell activation involved in immune responseGO:00022631260.013
atp catabolic processGO:0006200550.013
regulation of rac protein signal transductionGO:0035020190.013
divalent metal ion transportGO:00708381720.013
carbohydrate derivative biosynthetic processGO:19011371830.013
cellular chemical homeostasisGO:00550822150.013
organic anion transportGO:00157111370.013
covalent chromatin modificationGO:00165691630.013
cellular ion homeostasisGO:00068731650.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.013
regulation of neurotransmitter levelsGO:0001505870.013
plasma membrane organizationGO:0007009900.013
ear morphogenesisGO:00424711180.013
negative regulation of phosphorylationGO:00423261660.013
embryonic organ morphogenesisGO:00485622760.013
chromatin organizationGO:00063252060.013
cellular response to organonitrogen compoundGO:00714171450.013
negative regulation of cell developmentGO:00107211690.013
calcium ion transportGO:00068161590.013
membrane organizationGO:00610242450.013
multicellular organismal homeostasisGO:00488711640.013
divalent inorganic cation homeostasisGO:00725071380.013
mitotic cell cycle processGO:19030471590.013
neuron deathGO:00709971540.012
positive regulation of cell deathGO:00109422240.012
leukocyte activation involved in immune responseGO:00023661260.012
nitrogen compound transportGO:00717052710.012
muscle cell differentiationGO:00426922610.012
regulation of response to woundingGO:19030341890.012
regulation of alpha beta t cell activationGO:0046634530.012
positive regulation of programmed cell deathGO:00430682180.012
exocytosisGO:00068871210.012
epidermis developmentGO:00085441870.012
rna processingGO:00063961050.012
neuronal action potentialGO:0019228540.012
cellular response to peptideGO:1901653920.012
ribonucleoside monophosphate catabolic processGO:0009158570.012
germ cell developmentGO:00072811850.012
positive regulation of cell projection organizationGO:0031346950.012
oocyte constructionGO:000730820.012
regulation of cytokine productionGO:00018172660.012
positive regulation of growthGO:00459271040.012
stem cell proliferationGO:00720891170.012
cognitionGO:00508901490.012
gastrulationGO:00073691160.012
cellular metal ion homeostasisGO:00068751510.012
positive regulation of leukocyte differentiationGO:1902107860.012
nucleoside monophosphate catabolic processGO:0009125590.012
membrane lipid metabolic processGO:0006643530.012
male genitalia morphogenesisGO:004880840.012
single fertilizationGO:0007338820.012
carbohydrate metabolic processGO:00059752300.012
macromolecule methylationGO:00434141200.012
blastocyst developmentGO:0001824800.012
purine nucleoside monophosphate catabolic processGO:0009128580.011
establishment of vesicle localizationGO:0051650810.011
regulation of cellular response to stressGO:00801351590.011
leukocyte mediated immunityGO:00024431740.011
sensory perception of mechanical stimulusGO:00509541070.011
transmission of nerve impulseGO:0019226760.011
cellular response to lipidGO:00713961450.011
cellular response to growth factor stimulusGO:00713631970.011
positive regulation of lymphocyte activationGO:00512511400.011
neuron apoptotic processGO:00514021420.011
skeletal muscle organ developmentGO:00605381630.011
atp metabolic processGO:0046034750.011
regulation of actin cytoskeleton organizationGO:0032956840.011
phospholipid metabolic processGO:0006644870.011
glycoprotein metabolic processGO:00091001160.011
positive regulation of apoptotic processGO:00430652170.011
limb developmentGO:00601731660.011
male anatomical structure morphogenesisGO:009059840.011
regulation of nuclear cell cycle dna replicationGO:003326220.011
microtubule polymerization or depolymerizationGO:0031109260.011
gonad developmentGO:00084061410.011
negative regulation of immune system processGO:00026832090.011
double strand break repairGO:0006302480.011
response to light stimulusGO:00094161350.011
negative regulation of transferase activityGO:0051348850.011
cerebellar cortex developmentGO:0021695480.011
cation transmembrane transportGO:00986552660.011
microtubule cytoskeleton organization involved in mitosisGO:190285040.011
response to organic cyclic compoundGO:00140701980.011
cell substrate adhesionGO:00315891300.011
cellular component assembly involved in morphogenesisGO:00109271390.011
Human
alpha beta t cell activationGO:0046631910.011
metaphase plate congressionGO:005131020.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
peptidyl lysine modificationGO:0018205770.011
cilium assemblyGO:0042384810.011
Human
positive regulation of cell cycleGO:0045787920.011
regulation of actin filament polymerizationGO:0030833380.011
regulation of multi organism processGO:00439001110.011
oocyte axis specificationGO:000730920.011
regulation of t cell differentiationGO:0045580830.011
angiogenesisGO:00015252010.011
regulation of intracellular transportGO:00323861590.011
acetylcholine secretion neurotransmissionGO:001405520.011
regulation of map kinase activityGO:00434051200.011
regulation of transmembrane transportGO:00347621280.011
vesicle localizationGO:0051648860.011
regulation of endocytosisGO:0030100690.011
glycerolipid metabolic processGO:00464861220.010
glucose homeostasisGO:00425931280.010
morphogenesis of a branching structureGO:00017632030.010
telencephalon developmentGO:00215371860.010
purine ribonucleoside monophosphate catabolic processGO:0009169570.010
negative regulation of growthGO:0045926990.010
intraciliary transportGO:004207390.010
organophosphate biosynthetic processGO:00904071220.010
detection of abiotic stimulusGO:0009582600.010
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.010
negative regulation of protein phosphorylationGO:00019331260.010
regulation of t cell activationGO:00508631700.010
organonitrogen compound biosynthetic processGO:19015661920.010
morphogenesis of embryonic epitheliumGO:00163311590.010
positive regulation of cell adhesionGO:0045785800.010
negative regulation of phosphorus metabolic processGO:00105631840.010
glycerophospholipid metabolic processGO:0006650710.010
negative regulation of protein modification processGO:00314001630.010
regulation of actin filament lengthGO:0030832450.010
negative regulation of organelle organizationGO:0010639900.010
response to lipopolysaccharideGO:00324961280.010

Nek1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.028
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
organ system cancerDOID:005068600.024
central nervous system diseaseDOID:33100.022
neurodegenerative diseaseDOID:128900.018