Mus musculus

0 known processes

Nek8

NIMA (never in mitosis gene a)-related expressed kinase 8

(Aliases: 4632401F23Rik,jck)

Nek8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.337
renal system developmentGO:00720012250.188
Zebrafish
urogenital system developmentGO:00016552610.132
Zebrafish
left right pattern formationGO:0060972230.127
regulation of microtubule based processGO:0032886520.121
regulation of intracellular transportGO:00323861590.119
heart morphogenesisGO:00030071780.115
Zebrafish
regulation of cell projection organizationGO:00313442060.102
kidney developmentGO:00018222130.099
Zebrafish
establishment or maintenance of cell polarityGO:0007163860.078
regulation of cellular component sizeGO:00325351210.077
purine nucleotide metabolic processGO:00061633020.070
microtubule cytoskeleton organizationGO:00002261570.067
ribose phosphate metabolic processGO:00196932910.064
cilium morphogenesisGO:00602711020.062
regulation of reactive oxygen species biosynthetic processGO:190342620.060
regionalizationGO:00030023370.059
reactive nitrogen species metabolic processGO:200105700.058
nucleobase containing small molecule metabolic processGO:00550863520.057
regulation of nucleocytoplasmic transportGO:0046822730.055
transmembrane transportGO:00550854120.051
microtubule based processGO:00070172360.050
positive regulation of nervous system developmentGO:00519622210.050
intracellular protein transportGO:00068862040.050
regulation of nucleotide metabolic processGO:00061401690.050
ion transmembrane transportGO:00342203610.048
placenta developmentGO:00018901400.048
reactive oxygen species metabolic processGO:0072593840.047
liver developmentGO:0001889660.046
dna metabolic processGO:00062593030.046
regulation of system processGO:00440572000.046
ribonucleotide metabolic processGO:00092592910.045
establishment of mitochondrion localizationGO:005165440.044
negative regulation of cation channel activityGO:200125810.043
nucleotide metabolic processGO:00091173320.043
regulation of cytoskeleton organizationGO:00514931220.042
positive regulation of reactive oxygen species biosynthetic processGO:190342820.042
muscle system processGO:00030121410.039
establishment of protein localization to organelleGO:00725941180.039
cellular response to acidic phGO:007146840.039
microtubule based transportGO:0010970500.038
cation transmembrane transportGO:00986552660.037
kidney epithelium developmentGO:00720731210.037
purine containing compound metabolic processGO:00725213110.037
aromatic compound catabolic processGO:00194392860.037
muscle contractionGO:00069361010.037
positive regulation of cell developmentGO:00107202370.036
protein localization to organelleGO:00333651850.036
regulation of cell growthGO:0001558910.035
positive regulation of cell deathGO:00109422240.035
inorganic cation transmembrane transportGO:00986622070.035
regulation of protein kinase activityGO:00458592320.035
oxidation reduction processGO:00551143420.034
lung developmentGO:00303241640.034
cation transportGO:00068123990.034
cellular response to dna damage stimulusGO:00069742070.033
negative regulation of ryanodine sensitive calcium release channel activityGO:006031510.033
cytoplasmic transportGO:00164822340.033
negative regulation of intracellular transportGO:0032387380.033
cellular amino acid metabolic processGO:00065201030.033
cellular homeostasisGO:00197252400.033
wnt signaling pathwayGO:00160551880.032
regulation of anatomical structure sizeGO:00900661780.032
cation homeostasisGO:00550802120.032
positive regulation of reactive oxygen species metabolic processGO:2000379110.032
negative regulation of molecular functionGO:00440922580.032
macromolecule catabolic processGO:00090572810.032
protein catabolic processGO:00301632210.031
positive regulation of protein serine threonine kinase activityGO:00719021060.031
ribonucleoside triphosphate metabolic processGO:00091992200.031
cell adhesionGO:00071553290.031
organelle localizationGO:00516401790.031
regulation of cell sizeGO:0008361720.031
cellular nitrogen compound catabolic processGO:00442702800.030
leukocyte differentiationGO:00025213420.030
single organism cell adhesionGO:00986021560.030
male gamete generationGO:00482322850.030
embryonic organ morphogenesisGO:00485622760.030
Zebrafish
organonitrogen compound catabolic processGO:19015652640.030
protein targetingGO:00066051430.030
oocyte constructionGO:000730820.029
skeletal system morphogenesisGO:00487052030.029
intracellular mrna localizationGO:000829840.029
microtubule organizing center organizationGO:0031023280.029
regulation of wnt signaling pathwayGO:00301111230.029
organelle assemblyGO:00709251770.029
muscle cell differentiationGO:00426922610.028
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.028
canonical wnt signaling pathwayGO:00600701300.028
regulation of apoptotic signaling pathwayGO:20012331970.028
kidney morphogenesisGO:0060993830.028
Zebrafish
reactive oxygen species biosynthetic processGO:190340980.028
positive regulation of transferase activityGO:00513471670.027
regulation of cellular component biogenesisGO:00440871810.027
myeloid leukocyte differentiationGO:00025731190.027
regulation of multi organism processGO:00439001110.027
positive regulation of apoptotic processGO:00430652170.027
regulation of cytoplasmic transportGO:19036491120.027
cellular potassium ion transportGO:0071804430.026
regulation of ion transportGO:00432692150.026
regulation of cell cycleGO:00517262810.026
negative regulation of canonical wnt signaling pathwayGO:0090090510.026
heterocycle catabolic processGO:00467002800.025
nucleoside phosphate metabolic processGO:00067533380.025
regulation of spindle organizationGO:009022420.025
mitochondrion transport along microtubuleGO:004749730.025
positive regulation of programmed cell deathGO:00430682180.025
sequestering of metal ionGO:0051238190.025
single fertilizationGO:0007338820.025
detection of nodal flowGO:000312720.025
cellular ketone metabolic processGO:0042180840.025
response to acid chemicalGO:00011011110.025
t cell activationGO:00421102890.025
smoothened signaling pathwayGO:00072241050.024
sensory perceptionGO:00076002450.024
myeloid cell differentiationGO:00300992330.024
embryonic heart tube morphogenesisGO:0003143510.024
Zebrafish
amine metabolic processGO:0009308450.024
nephron developmentGO:00720061090.024
mesonephros developmentGO:0001823970.023
metanephric loop of henle developmentGO:007223640.023
positive regulation of protein phosphorylationGO:00019342420.023
negative regulation of cell cycleGO:00457861230.023
positive regulation of cell projection organizationGO:0031346950.023
regulation of transferase activityGO:00513382630.023
regulation of purine nucleotide metabolic processGO:19005421690.023
divalent inorganic cation homeostasisGO:00725071380.023
positive regulation of bindingGO:0051099490.023
ureteric bud developmentGO:0001657940.023
nucleocytoplasmic transportGO:00069131390.023
regulation of protein serine threonine kinase activityGO:00719001570.023
purine ribonucleoside triphosphate catabolic processGO:00092071990.023
purine nucleotide catabolic processGO:00061952110.022
cellular amine metabolic processGO:0044106440.022
maintenance of locationGO:0051235890.022
metanephric ascending thin limb developmentGO:007221820.022
inorganic ion transmembrane transportGO:00986602340.022
regulation of organelle organizationGO:00330432890.022
cellular chemical homeostasisGO:00550822150.022
regulation of canonical wnt signaling pathwayGO:0060828820.021
exocytosisGO:00068871210.021
muscle tissue developmentGO:00605373080.021
regulation of reactive oxygen species metabolic processGO:2000377400.021
divalent inorganic cation transportGO:00725111780.021
small gtpase mediated signal transductionGO:0007264970.021
regulation of cell cycle processGO:00105641600.021
intermediate filament cytoskeleton organizationGO:0045104260.021
divalent metal ion transportGO:00708381720.021
cilium assemblyGO:0042384810.021
nucleoside phosphate catabolic processGO:19012922220.021
cellular metal ion homeostasisGO:00068751510.021
small molecule biosynthetic processGO:00442831320.021
pole plasm assemblyGO:000731520.021
regulation of cellular catabolic processGO:00313292420.021
potassium ion transportGO:0006813520.021
nucleoside triphosphate catabolic processGO:00091432050.021
developmental maturationGO:00217001930.020
developmental growth involved in morphogenesisGO:00605601380.020
oocyte axis specificationGO:000730920.020
purine ribonucleotide catabolic processGO:00091542080.020
regulation of protein import into nucleusGO:0042306520.020
positive regulation of cell cycleGO:0045787920.020
cell cycle arrestGO:0007050370.020
spermatogenesisGO:00072832840.020
positive regulation of protein kinase activityGO:00458601440.020
negative regulation of cellular component organizationGO:00511291940.020
regulation of bindingGO:00510981110.020
maternal determination of anterior posterior axis embryoGO:000835820.020
embryonic heart tube left right pattern formationGO:006097150.020
organic cyclic compound catabolic processGO:19013612950.020
purine ribonucleotide metabolic processGO:00091502900.020
positive regulation of neuron differentiationGO:00456661410.019
cellular lipid metabolic processGO:00442553230.019
regulation of cell adhesionGO:00301551540.019
cellular amide metabolic processGO:0043603580.019
cellular macromolecule catabolic processGO:00442652060.019
metal ion homeostasisGO:00550651890.019
cytosolic calcium ion transportGO:0060401480.019
purine ribonucleoside metabolic processGO:00461282410.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
adult locomotory behaviorGO:0008344910.019
membrane organizationGO:00610242450.019
cellular response to acid chemicalGO:0071229680.019
hepaticobiliary system developmentGO:0061008670.019
apoptotic signaling pathwayGO:00971903060.019
inflammatory responseGO:00069542440.019
regulation of cytokine productionGO:00018172660.019
oocyte anterior posterior axis specificationGO:000731420.019
organelle transport along microtubuleGO:0072384140.019
locomotory behaviorGO:00076261950.018
cellular component assembly involved in morphogenesisGO:00109271390.018
regulation of cell morphogenesis involved in differentiationGO:00107691510.018
cellular response to cytokine stimulusGO:00713451890.018
regulation of defense responseGO:00313472330.018
regulation of establishment of protein localizationGO:00702011810.018
positive regulation of protein modification processGO:00314012990.018
response to reactive oxygen speciesGO:0000302560.018
determination of digestive tract left right asymmetryGO:007190710.018
gland developmentGO:00487323300.018
myeloid cell homeostasisGO:00022621140.018
single organismal cell cell adhesionGO:00163371310.018
purine nucleoside catabolic processGO:00061522050.018
mitotic cell cycleGO:00002781950.018
sequestering of calcium ionGO:0051208180.018
negative regulation of protein localization to nucleusGO:1900181230.018
purine nucleoside triphosphate catabolic processGO:00091462030.018
striated muscle tissue developmentGO:00147062930.018
organic hydroxy compound metabolic processGO:19016152030.017
ascending thin limb developmentGO:007202120.017
regulation of extent of cell growthGO:0061387520.017
macromolecular complex disassemblyGO:0032984430.017
purine ribonucleoside monophosphate metabolic processGO:0009167800.017
homeostasis of number of cellsGO:00488722100.017
nucleoside triphosphate metabolic processGO:00091412300.017
organophosphate catabolic processGO:00464342320.017
positive regulation of growthGO:00459271040.017
regulation of muscle system processGO:0090257800.017
monocarboxylic acid metabolic processGO:00327871910.017
cartilage developmentGO:00512161400.017
negative regulation of cellular protein metabolic processGO:00322692470.017
extrinsic apoptotic signaling pathwayGO:00971911260.017
lipid biosynthetic processGO:00086101790.017
striated muscle contractionGO:0006941450.017
regulation of cellular amine metabolic processGO:0033238200.017
branching morphogenesis of an epithelial tubeGO:00487541590.017
positive regulation of mapk cascadeGO:00434101700.017
morphogenesis of a branching structureGO:00017632030.017
regulation of neuron differentiationGO:00456642810.017
regulation of ion homeostasisGO:2000021640.017
embryonic placenta developmentGO:0001892980.017
camp metabolic processGO:0046058400.016
response to phGO:0009268140.016
regulation of kinase activityGO:00435492490.016
negative regulation of cell proliferationGO:00082852960.016
regulation of protein localizationGO:00328802310.016
response to organic cyclic compoundGO:00140701980.016
positive regulation of cellular amine metabolic processGO:003324050.016
organic anion transportGO:00157111370.016
regulation of cellular ketone metabolic processGO:0010565660.016
purine nucleoside metabolic processGO:00422782410.016
proteasomal protein catabolic processGO:0010498980.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of homeostatic processGO:00328441820.016
microtubule polymerization or depolymerizationGO:0031109260.016
blood vessel morphogenesisGO:00485142850.016
nucleoside catabolic processGO:00091642060.016
renal tubule developmentGO:0061326870.016
Zebrafish
retina homeostasisGO:0001895230.016
heart processGO:0003015940.016
protein import into nucleusGO:0006606950.016
extracellular matrix organizationGO:00301981470.016
skeletal system developmentGO:00015013560.016
regulation of intracellular protein transportGO:0033157820.016
positive regulation of kinase activityGO:00336741550.016
respiratory tube developmentGO:00303231670.015
positive regulation of cell cycle processGO:0090068610.015
matingGO:0007618270.015
protein ubiquitinationGO:00165671710.015
regulation of camp metabolic processGO:0030814300.015
negative regulation of wnt signaling pathwayGO:0030178730.015
camera type eye developmentGO:00430102660.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
nuclear transportGO:00511691390.015
protein importGO:00170381010.015
sodium ion transmembrane transportGO:0035725490.015
detection of external stimulusGO:0009581610.015
pancreas developmentGO:0031016570.015
protein complex disassemblyGO:0043241400.015
axonogenesisGO:00074092740.015
regulation of cellular response to stressGO:00801351590.015
cellular ion homeostasisGO:00068731650.015
positive regulation of cellular catabolic processGO:00313311480.015
calcium ion transportGO:00068161590.015
actin cytoskeleton organizationGO:00300362200.015
nucleoside metabolic processGO:00091162460.015
positive regulation of axon extensionGO:0045773200.015
cellular response to oxidative stressGO:0034599760.015
single organism nuclear importGO:1902593950.015
multi multicellular organism processGO:00447061090.015
ras protein signal transductionGO:0007265770.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
cellular protein complex disassemblyGO:0043624360.014
determination of left right symmetryGO:0007368800.014
Zebrafish
neuron projection extensionGO:1990138640.014
protein modification by small protein conjugation or removalGO:00706472070.014
negative regulation of cell cycle processGO:0010948690.014
epithelial tube morphogenesisGO:00605623030.014
Zebrafish
pharynx developmentGO:006046510.014
atp metabolic processGO:0046034750.014
heart contractionGO:0060047930.014
regulation of proteolysisGO:00301621640.014
Mouse
purine containing compound catabolic processGO:00725232130.014
intermediate filament based processGO:0045103270.014
jak stat cascadeGO:0007259420.014
regulation of protein bindingGO:0043393600.014
regulation of response to woundingGO:19030341890.014
calcium ion transmembrane transportGO:0070588850.014
negative regulation of protein complex disassemblyGO:0043242220.014
regulation of lymphocyte activationGO:00512492400.014
mitotic cell cycle processGO:19030471590.014
anatomical structure homeostasisGO:00602491450.014
release of sequestered calcium ion into cytosolGO:0051209420.014
rhodopsin mediated signaling pathwayGO:001605640.014
multicellular organism growthGO:00352641610.014
regulation of secretionGO:00510462740.014
stem cell differentiationGO:00488632680.014
multicellular organismal homeostasisGO:00488711640.014
response to inorganic substanceGO:0010035960.014
regulation of secretion by cellGO:19035302490.014
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
microtubule based movementGO:0007018840.013
nucleotide catabolic processGO:00091662170.013
regulation of cellular amino acid metabolic processGO:000652150.013
lymphocyte mediated immunityGO:00024491390.013
negative regulation of protein metabolic processGO:00512482820.013
humoral immune responseGO:0006959570.013
chemotaxisGO:00069352470.013
chromatin organizationGO:00063252060.013
response to nutrient levelsGO:00316671090.013
protein localization to nucleusGO:00345041210.013
cell maturationGO:00484691270.013
germ cell developmentGO:00072811850.013
dna repairGO:00062811070.013
regulation of reproductive processGO:2000241660.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.013
cellularizationGO:000734910.013
positive regulation of cell growthGO:0030307330.013
immune effector processGO:00022523210.013
organophosphate biosynthetic processGO:00904071220.013
g1 s transition of mitotic cell cycleGO:0000082570.013
epidermis developmentGO:00085441870.013
fertilizationGO:00095661270.013
positive regulation of cytosolic calcium ion concentrationGO:0007204650.013
embryonic heart tube developmentGO:0035050650.013
Zebrafish
nephron epithelium developmentGO:0072009920.013
negative regulation of phosphorylationGO:00423261660.013
organic acid biosynthetic processGO:0016053860.013
regulation of mitotic cell cycleGO:00073461260.013
negative regulation of nucleocytoplasmic transportGO:0046823230.013
positive regulation of hydrolase activityGO:00513451480.013
Mouse
calcium ion transport into cytosolGO:0060402480.013
maintenance of location in cellGO:0051651240.013
endocytosisGO:00068971680.013
connective tissue developmentGO:00614481790.012
cytosolic calcium ion homeostasisGO:0051480700.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
centrosome organizationGO:0051297260.012
mrna metabolic processGO:0016071840.012
oogenesisGO:0048477560.012
regulation of transmembrane transportGO:00347621280.012
cardiac chamber developmentGO:00032051080.012
midgut developmentGO:000749440.012
regulation of neuron projection developmentGO:00109751690.012
nitrogen compound transportGO:00717052710.012
transition metal ion homeostasisGO:0055076540.012
fat cell differentiationGO:00454441600.012
response to transforming growth factor betaGO:0071559880.012
anatomical structure maturationGO:0071695490.012
blood circulationGO:00080151950.012
digestive tract developmentGO:00485651900.012
cilium movementGO:0003341280.012
lateral inhibitionGO:004633110.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
carboxylic acid transportGO:00469421000.012
centrosome cycleGO:0007098230.012
potassium ion transmembrane transportGO:0071805430.012
cellular response to growth factor stimulusGO:00713631970.012
negative regulation of calcium ion transmembrane transporter activityGO:190102010.012
regulation of exocytosisGO:0017157610.012
regulation of metal ion transportGO:00109591060.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
cellular protein complex assemblyGO:00436231160.012
organonitrogen compound biosynthetic processGO:19015661920.012
detection of chemical stimulus involved in sensory perceptionGO:0050907100.012
negative regulation of phosphorus metabolic processGO:00105631840.012
translationGO:0006412930.012
positive regulation of cellular component biogenesisGO:0044089940.012
lymphocyte differentiationGO:00300982420.012
cell activation involved in immune responseGO:00022631260.012
glycoprotein biosynthetic processGO:0009101890.012
cellular response to inorganic substanceGO:0071241370.012
regulation of blood circulationGO:1903522930.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
response to oxidative stressGO:00069791230.011
regulation of cell cycle phase transitionGO:1901987770.011
detection of abiotic stimulusGO:0009582600.011
atp catabolic processGO:0006200550.011
response to radiationGO:00093141650.011
establishment of protein localization to membraneGO:0090150540.011
regulation of membrane potentialGO:00423911920.011
innate immune responseGO:00450871570.011
organic acid transportGO:00158491010.011
nephron tubule morphogenesisGO:0072078680.011
regulation of heart contractionGO:0008016770.011
ribonucleotide catabolic processGO:00092612080.011
hematopoietic progenitor cell differentiationGO:00022441430.011
renal tubule morphogenesisGO:0061333720.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
positive regulation of nucleotide metabolic processGO:00459811140.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
establishment of organelle localizationGO:00516561220.011
metanephros developmentGO:0001656790.011
protein depolymerizationGO:0051261340.011
epithelial cell proliferationGO:00506731740.011
retrograde transport endosome to golgiGO:004214720.011
regulation of lymphocyte differentiationGO:00456191070.011
cell growthGO:00160491300.011
mesonephric epithelium developmentGO:0072163940.011
substrate dependent cell migrationGO:0006929180.011
negative regulation of g1 s transition of mitotic cell cycleGO:2000134180.011
cell type specific apoptotic processGO:00972852680.011
peptidyl amino acid modificationGO:00181933360.011
smooth muscle contractionGO:0006939440.011
myosin filament organizationGO:003103330.011
cellular protein catabolic processGO:00442571550.011
purine ribonucleoside catabolic processGO:00461302050.011
striated muscle myosin thick filament assemblyGO:007168810.011
cellular calcium ion homeostasisGO:00068741190.011
lipid modificationGO:0030258650.011
cell cycle g1 s phase transitionGO:0044843570.011
protein modification by small protein conjugationGO:00324461870.011
antimicrobial peptide productionGO:000277520.011
negative regulation of organelle organizationGO:0010639900.011
nuclear importGO:0051170950.011
mitotic cytokinesisGO:000028140.011
cytokine productionGO:00018163190.011
negative regulation of mitotic cell cycleGO:0045930580.011
ribonucleotide biosynthetic processGO:0009260590.010
antimicrobial peptide biosynthetic processGO:000277720.010
regulation of microtubule cytoskeleton organizationGO:0070507370.010
cellular response to amino acid stimulusGO:0071230290.010
gtp catabolic processGO:00061841430.010
adult behaviorGO:00305341350.010
regulation of cysteine type endopeptidase activityGO:2000116650.010
Mouse
b cell activationGO:00421131610.010
meiotic cell cycle processGO:1903046770.010
stem cell developmentGO:00488642190.010
sensory perception of tasteGO:0050909180.010
regulation of protein catabolic processGO:00421761080.010
developmental cell growthGO:0048588840.010
regulation of inflammatory responseGO:00507271470.010
alpha beta t cell activationGO:0046631910.010
gonad developmentGO:00084061410.010
carbohydrate derivative catabolic processGO:19011362310.010
negative regulation of neuron deathGO:1901215980.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
response to light stimulusGO:00094161350.010
digestive tract morphogenesisGO:00485461470.010
regulation of gtp catabolic processGO:00331241130.010
nucleoside monophosphate catabolic processGO:0009125590.010
adaptive immune responseGO:00022501550.010
determination of heart left right asymmetryGO:0061371480.010
Zebrafish
ribonucleoside catabolic processGO:00424542060.010
cellular response to abiotic stimulusGO:0071214560.010
cell divisionGO:00513011200.010
nitric oxide metabolic processGO:0046209250.010
axon cargo transportGO:0008088330.010
regulation of protein targetingGO:1903533610.010
rna interferenceGO:001624620.010
circulatory system processGO:00030131970.010
segmentationGO:0035282930.010
rac protein signal transductionGO:0016601130.010
fatty acid metabolic processGO:00066311210.010
regulation of hydrolase activityGO:00513362460.010
Mouse

Nek8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nephronophthisisDOID:1271200.934
nervous system diseaseDOID:86300.029
sensory system diseaseDOID:005015500.029
disease of anatomical entityDOID:700.029
musculoskeletal system diseaseDOID:1700.013
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
connective tissue diseaseDOID:6500.010