IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Adam33

a disintegrin and metallopeptidase domain 33

(Aliases: Adaml)

Ensembl: ENSMUSG00000027318
Entrez: 110751
UniProtKB: Q923W9
UniProtKB: A2AP51

Process Predictions
Disease Predictions

Adam33 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transport	GO:0006812	399	0.272
leukocyte differentiation	GO:0002521	342	0.208	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.196
amine metabolic process	GO:0009308	45	0.180
muscle tissue development	GO:0060537	308	0.157
cellular amine metabolic process	GO:0044106	44	0.155
negative regulation of cell activation	GO:0050866	111	0.148
defense response to bacterium	GO:0042742	119	0.143
ion transmembrane transport	GO:0034220	361	0.132
lymphocyte differentiation	GO:0030098	242	0.131	Mouse
immune effector process	GO:0002252	321	0.129
regulation of cell activation	GO:0050865	289	0.121	Mouse
homeostasis of number of cells	GO:0048872	210	0.109	Mouse
t cell activation	GO:0042110	289	0.108	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.106
cytokine production	GO:0001816	319	0.105	Mouse
gland development	GO:0048732	330	0.105
striated muscle tissue development	GO:0014706	293	0.102
regulation of cellular ketone metabolic process	GO:0010565	66	0.101
cardiac muscle tissue development	GO:0048738	130	0.098
cellular response to growth factor stimulus	GO:0071363	197	0.096	Mouse
epidermis development	GO:0008544	187	0.092
transmembrane transport	GO:0055085	412	0.089
cellular ketone metabolic process	GO:0042180	84	0.085
muscle cell differentiation	GO:0042692	261	0.077
negative regulation of immune system process	GO:0002683	209	0.073
macromolecule catabolic process	GO:0009057	281	0.072	Mouse
response to growth factor	GO:0070848	198	0.071	Mouse
cell adhesion	GO:0007155	329	0.070	Mouse
male gamete generation	GO:0048232	285	0.070
regulation of ion transport	GO:0043269	215	0.069
membrane organization	GO:0061024	245	0.067
endocytosis	GO:0006897	168	0.067
leukocyte proliferation	GO:0070661	172	0.066
positive regulation of cellular amine metabolic process	GO:0033240	5	0.066
response to extracellular stimulus	GO:0009991	127	0.066
adaptive immune response	GO:0002250	155	0.065	Mouse
positive regulation of cytokine production	GO:0001819	174	0.064	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.064
divalent metal ion transport	GO:0070838	172	0.064
developmental growth involved in morphogenesis	GO:0060560	138	0.063
neuronal action potential	GO:0019228	54	0.063	Mouse
regulation of membrane potential	GO:0042391	192	0.063	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.063
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.063
mesenchymal cell development	GO:0014031	93	0.062	Mouse
negative regulation of growth	GO:0045926	99	0.061
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.059	Mouse
positive regulation of protein modification process	GO:0031401	299	0.057	Mouse
response to organic cyclic compound	GO:0014070	198	0.056	Mouse
i kappab kinase nf kappab signaling	GO:0007249	85	0.055
positive regulation of intracellular transport	GO:0032388	70	0.055
cation transmembrane transport	GO:0098655	266	0.055
muscle system process	GO:0003012	141	0.054
regulation of transferase activity	GO:0051338	263	0.054	Mouse
cell type specific apoptotic process	GO:0097285	268	0.054	Mouse
regulation of intracellular transport	GO:0032386	159	0.053
extracellular structure organization	GO:0043062	148	0.052
negative regulation of phosphate metabolic process	GO:0045936	184	0.051
action potential	GO:0001508	78	0.051	Mouse
cell fate commitment	GO:0045165	210	0.051
wound healing	GO:0042060	157	0.051
cytoplasmic transport	GO:0016482	234	0.050
axonogenesis	GO:0007409	274	0.050
regulation of neuron differentiation	GO:0045664	281	0.050
regulation of secretion	GO:0051046	274	0.049
calcium ion transport	GO:0006816	159	0.047
negative regulation of phosphorus metabolic process	GO:0010563	184	0.047
innate immune response	GO:0045087	157	0.047	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.047
extracellular matrix organization	GO:0030198	147	0.046
stem cell differentiation	GO:0048863	268	0.046	Mouse
learning or memory	GO:0007611	148	0.045	Mouse
response to acid chemical	GO:0001101	111	0.045
urogenital system development	GO:0001655	261	0.045
regulation of response to wounding	GO:1903034	189	0.044	Mouse
regulation of cytokine production	GO:0001817	266	0.044	Mouse
regulation of leukocyte proliferation	GO:0070663	121	0.044
aromatic compound catabolic process	GO:0019439	286	0.044
negative regulation of t cell activation	GO:0050868	65	0.043
skin development	GO:0043588	220	0.043
leukocyte mediated immunity	GO:0002443	174	0.043
skeletal muscle organ development	GO:0060538	163	0.043
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.042	Mouse
muscle contraction	GO:0006936	101	0.042
negative regulation of protein metabolic process	GO:0051248	282	0.042
regulation of cell adhesion	GO:0030155	154	0.042	Mouse
regulation of system process	GO:0044057	200	0.041
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.041
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.041
b cell activation	GO:0042113	161	0.041	Mouse
positive regulation of immune effector process	GO:0002699	107	0.040
intracellular protein transport	GO:0006886	204	0.040
organic anion transport	GO:0015711	137	0.040
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.040	Mouse
oxidation reduction process	GO:0055114	342	0.040
peptidyl tyrosine phosphorylation	GO:0018108	143	0.040
negative regulation of cellular component organization	GO:0051129	194	0.039
cell substrate adhesion	GO:0031589	130	0.039
nitrogen compound transport	GO:0071705	271	0.039
cellular homeostasis	GO:0019725	240	0.039
negative regulation of molecular function	GO:0044092	258	0.039
regulation of lymphocyte activation	GO:0051249	240	0.039	Mouse
organonitrogen compound biosynthetic process	GO:1901566	192	0.039
ras protein signal transduction	GO:0007265	77	0.038
divalent inorganic cation transport	GO:0072511	178	0.038
regulation of protein localization	GO:0032880	231	0.038
regulation of cell projection organization	GO:0031344	206	0.037
regulation of metal ion transport	GO:0010959	106	0.037
tissue remodeling	GO:0048771	102	0.037	Mouse
cellular metal ion homeostasis	GO:0006875	151	0.037
anion transport	GO:0006820	177	0.036
regulation of cell migration	GO:0030334	219	0.036	Mouse
telencephalon development	GO:0021537	186	0.036
neuron migration	GO:0001764	122	0.036
cognition	GO:0050890	149	0.035	Mouse
lung development	GO:0030324	164	0.035
positive regulation of phagocytosis	GO:0050766	26	0.035
positive regulation of lymphocyte activation	GO:0051251	140	0.035	Mouse
positive regulation of ion transport	GO:0043270	65	0.035
positive regulation of protein phosphorylation	GO:0001934	242	0.035	Mouse
digestive tract morphogenesis	GO:0048546	147	0.034
production of molecular mediator of immune response	GO:0002440	103	0.034
digestive tract development	GO:0048565	190	0.034
positive regulation of nervous system development	GO:0051962	221	0.034
regulation of adaptive immune response	GO:0002819	90	0.033
sequestering of calcium ion	GO:0051208	18	0.033
angiogenesis	GO:0001525	201	0.033	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.033
lymphocyte proliferation	GO:0046651	164	0.032
blood vessel morphogenesis	GO:0048514	285	0.032	Mouse
myeloid cell differentiation	GO:0030099	233	0.032
skeletal system development	GO:0001501	356	0.032
positive regulation of cell development	GO:0010720	237	0.032
regulation of lymphocyte proliferation	GO:0050670	117	0.031
cellular response to extracellular stimulus	GO:0031668	81	0.031
forebrain cell migration	GO:0021885	58	0.031
peptidyl amino acid modification	GO:0018193	336	0.031
regulation of cell cycle	GO:0051726	281	0.031
lateral inhibition	GO:0046331	1	0.031
cellular response to acid chemical	GO:0071229	68	0.031
neuromuscular process	GO:0050905	99	0.030
learning	GO:0007612	98	0.030	Mouse
negative regulation of multi organism process	GO:0043901	68	0.030	Mouse
positive regulation of cell motility	GO:2000147	116	0.030	Mouse
actin cytoskeleton organization	GO:0030036	220	0.030
g protein coupled receptor signaling pathway	GO:0007186	243	0.030
alpha beta t cell differentiation	GO:0046632	69	0.030
regulation of t cell activation	GO:0050863	170	0.029	Mouse
lymphocyte mediated immunity	GO:0002449	139	0.029
positive regulation of protein secretion	GO:0050714	52	0.029
lymphocyte homeostasis	GO:0002260	64	0.029
hematopoietic progenitor cell differentiation	GO:0002244	143	0.029
segmentation	GO:0035282	93	0.029
negative regulation of phosphorylation	GO:0042326	166	0.029
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.029
response to organonitrogen compound	GO:0010243	246	0.028
negative regulation of intracellular signal transduction	GO:1902532	167	0.028
muscle cell development	GO:0055001	133	0.028
regulation of organelle organization	GO:0033043	289	0.028
posttranscriptional regulation of gene expression	GO:0010608	155	0.028
heart morphogenesis	GO:0003007	178	0.028	Mouse
developmental cell growth	GO:0048588	84	0.028
detection of bacterium	GO:0016045	7	0.027
regulation of protein transport	GO:0051223	163	0.027
regulation of ossification	GO:0030278	112	0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.027	Mouse
neuron death	GO:0070997	154	0.027	Mouse
regulation of multi organism process	GO:0043900	111	0.027	Mouse
negative regulation of lymphocyte activation	GO:0051250	91	0.027
immunoglobulin mediated immune response	GO:0016064	69	0.027
t cell proliferation	GO:0042098	120	0.027
negative regulation of nervous system development	GO:0051961	156	0.027
cellular ion homeostasis	GO:0006873	165	0.027
dna metabolic process	GO:0006259	303	0.027
circadian rhythm	GO:0007623	114	0.027
striated muscle cell development	GO:0055002	125	0.027
negative regulation of cell development	GO:0010721	169	0.026
regulation of vesicle mediated transport	GO:0060627	139	0.026
respiratory system development	GO:0060541	190	0.026
forebrain development	GO:0030900	302	0.026
neuron projection guidance	GO:0097485	141	0.026
spermatogenesis	GO:0007283	284	0.026
protein localization to nucleus	GO:0034504	121	0.026
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.026
organ growth	GO:0035265	117	0.026
regulation of protein kinase activity	GO:0045859	232	0.025	Mouse
regulation of cytoplasmic transport	GO:1903649	112	0.025
protein processing	GO:0016485	163	0.025
leukocyte activation involved in immune response	GO:0002366	126	0.025
protein secretion	GO:0009306	111	0.025
positive regulation of homeostatic process	GO:0032846	64	0.025	Mouse
response to transforming growth factor beta	GO:0071559	88	0.025	Mouse
regulation of proteolysis	GO:0030162	164	0.025	Mouse
sequestering of metal ion	GO:0051238	19	0.025
monocarboxylic acid metabolic process	GO:0032787	191	0.024
digestive system development	GO:0055123	200	0.024
transmission of nerve impulse	GO:0019226	76	0.024	Mouse
renal system development	GO:0072001	225	0.024
single organism cell adhesion	GO:0098602	156	0.024	Mouse
metal ion homeostasis	GO:0055065	189	0.024
regulation of blood circulation	GO:1903522	93	0.024
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.024
negative regulation of cellular protein metabolic process	GO:0032269	247	0.023
cellular response to lipid	GO:0071396	145	0.023
organonitrogen compound catabolic process	GO:1901565	264	0.023
negative regulation of cell migration	GO:0030336	59	0.023
regulation of protein kinase b signaling	GO:0051896	56	0.023	Mouse
meiotic nuclear division	GO:0007126	115	0.023
protein catabolic process	GO:0030163	221	0.023	Mouse
organic hydroxy compound metabolic process	GO:1901615	203	0.023
multicellular organism growth	GO:0035264	161	0.023
regulation of endocytosis	GO:0030100	69	0.023
nuclear division	GO:0000280	158	0.023
rho protein signal transduction	GO:0007266	32	0.023
negative regulation of neuron death	GO:1901215	98	0.022	Mouse
regulation of ras protein signal transduction	GO:0046578	114	0.022
regulation of wnt signaling pathway	GO:0030111	123	0.022
cell division	GO:0051301	120	0.022
positive regulation of leukocyte mediated immunity	GO:0002705	70	0.022
negative regulation of neuron projection development	GO:0010977	50	0.022
germ cell development	GO:0007281	185	0.022
positive regulation of cell migration	GO:0030335	109	0.022	Mouse
regulation of protein secretion	GO:0050708	82	0.022
regionalization	GO:0003002	337	0.022
small molecule biosynthetic process	GO:0044283	132	0.022
purine ribonucleoside catabolic process	GO:0046130	205	0.022
protein kinase b signaling	GO:0043491	74	0.022	Mouse
regulation of establishment of protein localization	GO:0070201	181	0.022
regulation of inflammatory response	GO:0050727	147	0.022	Mouse
stem cell development	GO:0048864	219	0.022	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.022
single organismal cell cell adhesion	GO:0016337	131	0.022	Mouse
maintenance of location	GO:0051235	89	0.022
mesoderm development	GO:0007498	100	0.022
morphogenesis of embryonic epithelium	GO:0016331	159	0.022
regulation of t cell proliferation	GO:0042129	92	0.021
determination of left right symmetry	GO:0007368	80	0.021
regulation of cell motility	GO:2000145	236	0.021	Mouse
multicellular organismal signaling	GO:0035637	91	0.021	Mouse
regulation of stem cell proliferation	GO:0072091	78	0.021
protein localization to membrane	GO:0072657	108	0.021
regulation of hydrolase activity	GO:0051336	246	0.021
detection of stimulus	GO:0051606	84	0.021
morphogenesis of an endothelium	GO:0003159	2	0.021
regulation of leukocyte differentiation	GO:1902105	159	0.021	Mouse
t cell differentiation	GO:0030217	174	0.021	Mouse
ensheathment of neurons	GO:0007272	76	0.021	Mouse
regulation of muscle tissue development	GO:1901861	97	0.021
endocrine system development	GO:0035270	98	0.021
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.021	Mouse
cation homeostasis	GO:0055080	212	0.021
interleukin 8 production	GO:0032637	4	0.021
positive regulation of hydrolase activity	GO:0051345	148	0.020
positive regulation of lymphocyte mediated immunity	GO:0002708	62	0.020
molting cycle	GO:0042303	90	0.020
sensory perception	GO:0007600	245	0.020
cell growth	GO:0016049	130	0.020
alpha beta t cell activation	GO:0046631	91	0.020
cardiac muscle cell development	GO:0055013	39	0.020
memory	GO:0007613	58	0.020
negative regulation of t cell proliferation	GO:0042130	38	0.020
cytokine metabolic process	GO:0042107	71	0.020
nucleoside triphosphate metabolic process	GO:0009141	230	0.020
camera type eye development	GO:0043010	266	0.020
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.020	Mouse
neuron projection extension	GO:1990138	64	0.020
alcohol metabolic process	GO:0006066	116	0.020
cellular response to biotic stimulus	GO:0071216	92	0.020
response to nutrient levels	GO:0031667	109	0.020
skeletal system morphogenesis	GO:0048705	203	0.019
chemotaxis	GO:0006935	247	0.019	Mouse
organic hydroxy compound transport	GO:0015850	93	0.019
calcium ion transmembrane transport	GO:0070588	85	0.019
organelle localization	GO:0051640	179	0.019
ossification	GO:0001503	216	0.019
regulation of lymphocyte mediated immunity	GO:0002706	84	0.019
response to amino acid	GO:0043200	37	0.019
synaptic transmission	GO:0007268	329	0.019
ear development	GO:0043583	200	0.019
axon guidance	GO:0007411	141	0.019
synapse organization	GO:0050808	125	0.019
negative regulation of neuron differentiation	GO:0045665	101	0.019
mapk cascade	GO:0000165	281	0.019	Mouse
negative regulation of cell motility	GO:2000146	61	0.019
regulation of anatomical structure size	GO:0090066	178	0.019
regulation of calcium ion transport	GO:0051924	69	0.019
kidney development	GO:0001822	213	0.019
exocytosis	GO:0006887	121	0.019
positive regulation of mapk cascade	GO:0043410	170	0.019	Mouse
negative regulation of wnt signaling pathway	GO:0030178	73	0.019
regulation of kinase activity	GO:0043549	249	0.019	Mouse
regulation of neuron projection development	GO:0010975	169	0.018
regulation of phospholipase c activity	GO:1900274	3	0.018
cellular chemical homeostasis	GO:0055082	215	0.018
cardiocyte differentiation	GO:0035051	87	0.018
cytokine secretion	GO:0050663	72	0.018
microtubule cytoskeleton organization	GO:0000226	157	0.018
inorganic cation transmembrane transport	GO:0098662	207	0.018
single organism nuclear import	GO:1902593	95	0.018
organelle fission	GO:0048285	170	0.018
regulation of cellular component size	GO:0032535	121	0.018
connective tissue development	GO:0061448	179	0.018
immune response regulating signaling pathway	GO:0002764	125	0.018	Mouse
positive regulation of kinase activity	GO:0033674	155	0.018	Mouse
positive regulation of adaptive immune response	GO:0002821	61	0.018
inflammatory response	GO:0006954	244	0.018	Mouse
positive regulation of protein kinase activity	GO:0045860	144	0.018	Mouse
cellular nitrogen compound catabolic process	GO:0044270	280	0.018
cardiac ventricle development	GO:0003231	83	0.018
regulation of protein complex assembly	GO:0043254	83	0.018
negative regulation of leukocyte proliferation	GO:0070664	46	0.018
mitotic cell cycle	GO:0000278	195	0.018
regulation of leukocyte mediated immunity	GO:0002703	104	0.018
inorganic ion transmembrane transport	GO:0098660	234	0.018
protein maturation	GO:0051604	176	0.018
b cell mediated immunity	GO:0019724	71	0.018
response to radiation	GO:0009314	165	0.017	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.017
olfactory learning	GO:0008355	2	0.017
regulation of cell size	GO:0008361	72	0.017
blastocyst development	GO:0001824	80	0.017
cellular amide metabolic process	GO:0043603	58	0.017
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.017
nucleoside catabolic process	GO:0009164	206	0.017
multicellular organismal homeostasis	GO:0048871	164	0.017	Mouse
positive regulation of cell adhesion	GO:0045785	80	0.017	Mouse
leukocyte homeostasis	GO:0001776	79	0.017	Mouse
cellular response to hormone stimulus	GO:0032870	150	0.017
epithelial tube morphogenesis	GO:0060562	303	0.017
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.017	Mouse
positive regulation of programmed cell death	GO:0043068	218	0.017	Mouse
epithelial cell development	GO:0002064	159	0.017
protein modification by small protein conjugation	GO:0032446	187	0.017
compound eye development	GO:0048749	1	0.017
response to metal ion	GO:0010038	47	0.017
axon ensheathment	GO:0008366	76	0.017	Mouse
cell activation involved in immune response	GO:0002263	126	0.016
regulation of t cell differentiation	GO:0045580	83	0.016	Mouse
tumor necrosis factor superfamily cytokine production	GO:0071706	51	0.016	Mouse
divalent inorganic cation homeostasis	GO:0072507	138	0.016
negative regulation of endothelial cell migration	GO:0010596	4	0.016
leukocyte migration	GO:0050900	124	0.016	Mouse
asymmetric stem cell division	GO:0098722	3	0.016
dendrite development	GO:0016358	115	0.016
regulation of striated muscle cell differentiation	GO:0051153	81	0.016
negative regulation of lymphocyte proliferation	GO:0050672	45	0.016
glucose homeostasis	GO:0042593	128	0.016
protein targeting	GO:0006605	143	0.016
mitotic cytokinesis	GO:0000281	4	0.016
positive regulation of protein transport	GO:0051222	93	0.016
adult behavior	GO:0030534	135	0.016	Mouse
stem cell proliferation	GO:0072089	117	0.016
cell recognition	GO:0008037	83	0.016	Mouse
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.016
positive regulation of vasoconstriction	GO:0045907	4	0.016
sensory organ morphogenesis	GO:0090596	242	0.016
peptide metabolic process	GO:0006518	46	0.016
immunoglobulin production	GO:0002377	73	0.016
cytosolic calcium ion homeostasis	GO:0051480	70	0.016
notch signaling pathway	GO:0007219	71	0.016
engulfment of apoptotic cell	GO:0043652	3	0.016
meiotic cell cycle	GO:0051321	122	0.016
neural tube development	GO:0021915	160	0.016
purine ribonucleoside metabolic process	GO:0046128	241	0.015
central nervous system neuron differentiation	GO:0021953	162	0.015
response to inorganic substance	GO:0010035	96	0.015
positive regulation of leukocyte differentiation	GO:1902107	86	0.015	Mouse
regulation of phagocytosis	GO:0050764	33	0.015
regulation of cardiac muscle tissue growth	GO:0055021	26	0.015
regulation of lymphocyte differentiation	GO:0045619	107	0.015	Mouse
positive regulation of endocytosis	GO:0045807	42	0.015
fat cell differentiation	GO:0045444	160	0.015
erk1 and erk2 cascade	GO:0070371	77	0.015
cellular macromolecule catabolic process	GO:0044265	206	0.015
regulation of cytoskeleton organization	GO:0051493	122	0.015
striated muscle cell proliferation	GO:0014855	39	0.015
negative regulation of protein modification process	GO:0031400	163	0.015
regulation of secretion by cell	GO:1903530	249	0.015
positive regulation of cytoplasmic transport	GO:1903651	40	0.015
apoptotic signaling pathway	GO:0097190	306	0.015
positive regulation of interleukin 8 production	GO:0032757	2	0.015
regulation of interleukin 8 production	GO:0032677	3	0.015
regulation of canonical wnt signaling pathway	GO:0060828	82	0.015
t cell differentiation in thymus	GO:0033077	77	0.015	Mouse
telencephalon cell migration	GO:0022029	55	0.015
embryonic placenta development	GO:0001892	98	0.015
negative regulation of protein phosphorylation	GO:0001933	126	0.015
organophosphate catabolic process	GO:0046434	232	0.015
phagocytosis	GO:0006909	66	0.015
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.015
cellular lipid metabolic process	GO:0044255	323	0.015
carbohydrate homeostasis	GO:0033500	128	0.014
positive regulation of production of molecular mediator of immune response	GO:0002702	45	0.014
negative regulation of cytokine production	GO:0001818	84	0.014
response to light stimulus	GO:0009416	135	0.014	Mouse
detection of molecule of bacterial origin	GO:0032490	2	0.014
second messenger mediated signaling	GO:0019932	73	0.014
positive regulation of transferase activity	GO:0051347	167	0.014	Mouse
regulation of mitotic cell cycle	GO:0007346	126	0.014
regulation of erk1 and erk2 cascade	GO:0070372	71	0.014
negative regulation of cell projection organization	GO:0031345	56	0.014
regulation of vasculature development	GO:1901342	88	0.014
endomembrane system organization	GO:0010256	147	0.014
lipid localization	GO:0010876	126	0.014
t cell mediated immunity	GO:0002456	50	0.014
protein localization to organelle	GO:0033365	185	0.014
carbohydrate metabolic process	GO:0005975	230	0.014
regulation of voltage gated calcium channel activity	GO:1901385	4	0.014
morphogenesis of a branching epithelium	GO:0061138	193	0.014
tissue homeostasis	GO:0001894	115	0.014	Mouse
regulation of b cell activation	GO:0050864	81	0.014
spermatid differentiation	GO:0048515	115	0.014
respiratory tube development	GO:0030323	167	0.014
modification dependent protein catabolic process	GO:0019941	133	0.014
positive regulation of mesenchymal cell proliferation involved in ureter development	GO:2000729	3	0.014
rhythmic process	GO:0048511	174	0.014
mammary gland epithelium development	GO:0061180	65	0.014
peripheral nervous system development	GO:0007422	53	0.014	Mouse
nucleotide metabolic process	GO:0009117	332	0.014
regulation of cardiac muscle tissue development	GO:0055024	31	0.014
regulation of cell substrate adhesion	GO:0010810	73	0.014
fertilization	GO:0009566	127	0.014	Mouse
leukocyte apoptotic process	GO:0071887	71	0.013	Mouse
regulation of cellular component biogenesis	GO:0044087	181	0.013
regulation of renal sodium excretion	GO:0035813	3	0.013
plasma membrane organization	GO:0007009	90	0.013
reactive oxygen species metabolic process	GO:0072593	84	0.013
tumor necrosis factor production	GO:0032640	50	0.013
response to molecule of bacterial origin	GO:0002237	143	0.013
purine nucleotide metabolic process	GO:0006163	302	0.013
fatty acid metabolic process	GO:0006631	121	0.013
positive regulation of cell activation	GO:0050867	158	0.013	Mouse
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.013	Mouse
organophosphate biosynthetic process	GO:0090407	122	0.013
cellular response to fibroblast growth factor stimulus	GO:0044344	47	0.013
establishment of protein localization to organelle	GO:0072594	118	0.013
positive regulation of proteolysis	GO:0045862	85	0.013	Mouse
regulation of wound healing	GO:0061041	40	0.013
actomyosin structure organization	GO:0031032	56	0.013
activation of mapk activity	GO:0000187	59	0.013	Mouse
cellular response to external stimulus	GO:0071496	88	0.013
acid secretion	GO:0046717	33	0.013
cytokine biosynthetic process	GO:0042089	68	0.013
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.013
epithelial tube formation	GO:0072175	130	0.013
regulation of ion transmembrane transport	GO:0034765	119	0.013
positive regulation of eosinophil migration	GO:2000418	2	0.013	Mouse
cellular response to dna damage stimulus	GO:0006974	207	0.013
microtubule based process	GO:0007017	236	0.013
defense response to other organism	GO:0098542	197	0.013
lymphocyte apoptotic process	GO:0070227	54	0.013	Mouse
positive regulation of muscle cell differentiation	GO:0051149	39	0.013
physiological cardiac muscle hypertrophy	GO:0003301	3	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013
bone development	GO:0060348	120	0.013
cardiac chamber development	GO:0003205	108	0.013
myotube differentiation	GO:0014902	105	0.013
heterocycle catabolic process	GO:0046700	280	0.013
activation of innate immune response	GO:0002218	56	0.013	Mouse
regulation of body fluid levels	GO:0050878	162	0.013
signal transduction in absence of ligand	GO:0038034	55	0.013
sperm egg recognition	GO:0035036	37	0.013	Mouse
immune response activating signal transduction	GO:0002757	116	0.013	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.013
positive regulation of growth	GO:0045927	104	0.012
positive regulation of cytokine secretion	GO:0050715	41	0.012
calcium ion homeostasis	GO:0055074	127	0.012
regulation of nucleocytoplasmic transport	GO:0046822	73	0.012
regulation of epithelial cell proliferation	GO:0050678	141	0.012
myeloid leukocyte activation	GO:0002274	83	0.012
protein ubiquitination	GO:0016567	171	0.012
protein import into nucleus	GO:0006606	95	0.012
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.012
organelle assembly	GO:0070925	177	0.012
regulation of cell growth	GO:0001558	91	0.012
retina development in camera type eye	GO:0060041	119	0.012
regulation of extent of cell growth	GO:0061387	52	0.012
collagen fibril organization	GO:0030199	32	0.012
sensory perception of chemical stimulus	GO:0007606	51	0.012
response to peptide hormone	GO:0043434	127	0.012
odontogenesis	GO:0042476	78	0.012
multi organism behavior	GO:0051705	62	0.012
cellular response to starvation	GO:0009267	57	0.012
regulation of immunoglobulin mediated immune response	GO:0002889	37	0.012
lipid biosynthetic process	GO:0008610	179	0.012
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.012
cellular response to organic cyclic compound	GO:0071407	87	0.012
asymmetric neuroblast division	GO:0055059	1	0.012
negative regulation of cellular amine metabolic process	GO:0033239	1	0.012

Adam33 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.032
disease of anatomical entity	DOID:7	0.032
disease by infectious agent	DOID:0050117	0.020
viral infectious disease	DOID:934	0.020
nervous system disease	DOID:863	0.020
connective tissue disease	DOID:65	0.019
human immunodeficiency virus infectious disease	DOID:526	0.016
acquired immunodeficiency syndrome	DOID:635	0.016

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