IMP: Integrative Multi-species Prediction

Mus musculus

41 known processes

C1qtnf5

C1q and tumor necrosis factor related protein 5

(Aliases: Ctrp5)

Entrez: 235312
Ensembl: ENSMUSG00000079592
UniProtKB: Q4ZJN4
UniProtKB: Q8K479

Process Predictions
Disease Predictions

C1qtnf5 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
oxidation reduction process	GO:0055114	342	0.161	Mouse
fat soluble vitamin biosynthetic process	GO:0042362	4	0.154
cellular lipid catabolic process	GO:0044242	52	0.133	Mouse
regulation of membrane potential	GO:0042391	192	0.133
lipid biosynthetic process	GO:0008610	179	0.131
purine containing compound metabolic process	GO:0072521	311	0.116
cellular lipid metabolic process	GO:0044255	323	0.113	Mouse
nucleotide metabolic process	GO:0009117	332	0.112
purine nucleotide metabolic process	GO:0006163	302	0.098
carbohydrate derivative biosynthetic process	GO:1901137	183	0.097
cellular response to organonitrogen compound	GO:0071417	145	0.096	Mouse
cellular response to peptide	GO:1901653	92	0.085	Mouse
purine ribonucleotide metabolic process	GO:0009150	290	0.084
reactive oxygen species metabolic process	GO:0072593	84	0.083
nucleoside phosphate metabolic process	GO:0006753	338	0.076
photoreceptor cell development	GO:0042461	40	0.075
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.074	Mouse
isoprenoid catabolic process	GO:0008300	2	0.072
terpenoid metabolic process	GO:0006721	25	0.071
cellular ketone metabolic process	GO:0042180	84	0.067	Mouse
sensory organ morphogenesis	GO:0090596	242	0.066
response to peptide	GO:1901652	136	0.065	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.062
skeletal system development	GO:0001501	356	0.062
cellular response to insulin stimulus	GO:0032869	78	0.060	Mouse
visual perception	GO:0007601	52	0.060
response to uv	GO:0009411	44	0.059
ribonucleotide metabolic process	GO:0009259	291	0.058
camera type eye development	GO:0043010	266	0.058
ribose phosphate metabolic process	GO:0019693	291	0.057
transmembrane transport	GO:0055085	412	0.054
detection of abiotic stimulus	GO:0009582	60	0.051
developmental pigmentation	GO:0048066	40	0.047
response to organonitrogen compound	GO:0010243	246	0.044	Mouse
response to light stimulus	GO:0009416	135	0.044
response to insulin	GO:0032868	100	0.044	Mouse
cellular response to peptide hormone stimulus	GO:0071375	92	0.043	Mouse
sensory perception	GO:0007600	245	0.042
purine nucleotide biosynthetic process	GO:0006164	65	0.040
fat soluble vitamin metabolic process	GO:0006775	11	0.040
retina morphogenesis in camera type eye	GO:0060042	45	0.040
small gtpase mediated signal transduction	GO:0007264	97	0.039
cellular response to hormone stimulus	GO:0032870	150	0.039	Mouse
small molecule biosynthetic process	GO:0044283	132	0.038
insulin receptor signaling pathway	GO:0008286	49	0.038
organophosphate biosynthetic process	GO:0090407	122	0.038
organonitrogen compound biosynthetic process	GO:1901566	192	0.037
retinal metabolic process	GO:0042574	5	0.036
germ cell development	GO:0007281	185	0.036
nucleotide biosynthetic process	GO:0009165	78	0.036
cell maturation	GO:0048469	127	0.035
purine ribonucleotide biosynthetic process	GO:0009152	59	0.034
cellular response to light stimulus	GO:0071482	19	0.034
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.034
regulation of cellular catabolic process	GO:0031329	242	0.034
amine metabolic process	GO:0009308	45	0.034
regionalization	GO:0003002	337	0.033
pigmentation	GO:0043473	71	0.033
ion transmembrane transport	GO:0034220	361	0.033
regulation of multi organism process	GO:0043900	111	0.032
multicellular organismal homeostasis	GO:0048871	164	0.032
muscle tissue development	GO:0060537	308	0.032
vitamin a metabolic process	GO:0006776	2	0.032
cyclic nucleotide metabolic process	GO:0009187	59	0.032
regulation of rhodopsin gene expression	GO:0007468	3	0.032
cellular amino acid metabolic process	GO:0006520	103	0.032
pigment biosynthetic process	GO:0046148	26	0.032
protein processing	GO:0016485	163	0.031
retina development in camera type eye	GO:0060041	119	0.031
anion transport	GO:0006820	177	0.030
cation transport	GO:0006812	399	0.029
meiotic cell cycle	GO:0051321	122	0.029
regulation of reproductive process	GO:2000241	66	0.029
nucleoside phosphate biosynthetic process	GO:1901293	79	0.029
protein maturation	GO:0051604	176	0.029
regulation of cellular ketone metabolic process	GO:0010565	66	0.028	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.028
positive regulation of cellular amine metabolic process	GO:0033240	5	0.027
cgmp biosynthetic process	GO:0006182	13	0.027
cell type specific apoptotic process	GO:0097285	268	0.027
bone development	GO:0060348	120	0.027
cyclic nucleotide biosynthetic process	GO:0009190	44	0.027
negative regulation of cell cycle	GO:0045786	123	0.027
cation transmembrane transport	GO:0098655	266	0.026
cyclic purine nucleotide metabolic process	GO:0052652	43	0.026
negative regulation of cell development	GO:0010721	169	0.026
ribose phosphate biosynthetic process	GO:0046390	59	0.025
positive regulation of cellular catabolic process	GO:0031331	148	0.025
developmental maturation	GO:0021700	193	0.025
detection of light stimulus	GO:0009583	25	0.024
regulation of cell cycle	GO:0051726	281	0.023
cellular homeostasis	GO:0019725	240	0.023
purine containing compound biosynthetic process	GO:0072522	70	0.023
regulation of secretion	GO:0051046	274	0.023
guanosine containing compound metabolic process	GO:1901068	144	0.023
regulation of cell activation	GO:0050865	289	0.023
amide transport	GO:0042886	138	0.022
ras protein signal transduction	GO:0007265	77	0.022
striated muscle tissue development	GO:0014706	293	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.021
maintenance of location	GO:0051235	89	0.021
glycoprotein metabolic process	GO:0009100	116	0.020
detection of external stimulus	GO:0009581	61	0.020
regulation of apoptotic signaling pathway	GO:2001233	197	0.020
ribonucleotide biosynthetic process	GO:0009260	59	0.019
positive regulation of cell death	GO:0010942	224	0.019
regulation of neuron differentiation	GO:0045664	281	0.019
urogenital system development	GO:0001655	261	0.019	Mouse
nitrogen compound transport	GO:0071705	271	0.019
cellular response to dna damage stimulus	GO:0006974	207	0.019
cellular response to abiotic stimulus	GO:0071214	56	0.019
regulation of secretion by cell	GO:1903530	249	0.019
cellular response to radiation	GO:0071478	28	0.019
macromolecule catabolic process	GO:0009057	281	0.019
negative regulation of protein metabolic process	GO:0051248	282	0.018	Mouse
monosaccharide metabolic process	GO:0005996	106	0.018	Mouse
aromatic compound catabolic process	GO:0019439	286	0.018
intrinsic apoptotic signaling pathway	GO:0097193	132	0.018
purine ribonucleoside catabolic process	GO:0046130	205	0.018
detection of stimulus	GO:0051606	84	0.018
cellular nitrogen compound catabolic process	GO:0044270	280	0.018
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.018
purine ribonucleotide catabolic process	GO:0009154	208	0.018
negative regulation of meiotic cell cycle	GO:0051447	14	0.017
purine containing compound catabolic process	GO:0072523	213	0.017
nucleoside catabolic process	GO:0009164	206	0.017
regulation of vesicle mediated transport	GO:0060627	139	0.017
glycosyl compound metabolic process	GO:1901657	246	0.017
respiratory tube development	GO:0030323	167	0.017
multicellular organism growth	GO:0035264	161	0.017
forebrain development	GO:0030900	302	0.017
positive regulation of programmed cell death	GO:0043068	218	0.017
male gamete generation	GO:0048232	285	0.017
homeostasis of number of cells	GO:0048872	210	0.017
morphogenesis of a branching structure	GO:0001763	203	0.016
cellular aldehyde metabolic process	GO:0006081	12	0.016
organic cyclic compound catabolic process	GO:1901361	295	0.016
pigment metabolic process	GO:0042440	32	0.016
regulation of cellular amine metabolic process	GO:0033238	20	0.016
diterpenoid biosynthetic process	GO:0016102	7	0.016
terpenoid biosynthetic process	GO:0016114	7	0.016
negative regulation of immune system process	GO:0002683	209	0.016
rhythmic process	GO:0048511	174	0.016
apoptotic signaling pathway	GO:0097190	306	0.016
positive regulation of nucleotide metabolic process	GO:0045981	114	0.016
nucleoside metabolic process	GO:0009116	246	0.016
detection of visible light	GO:0009584	14	0.016
cellular chemical homeostasis	GO:0055082	215	0.016
organophosphate catabolic process	GO:0046434	232	0.016
negative regulation of intracellular signal transduction	GO:1902532	167	0.016	Mouse
connective tissue development	GO:0061448	179	0.016
inorganic cation transmembrane transport	GO:0098662	207	0.015
spermatogenesis	GO:0007283	284	0.015
carbohydrate derivative catabolic process	GO:1901136	231	0.015
heterocycle catabolic process	GO:0046700	280	0.015
ribonucleoside catabolic process	GO:0042454	206	0.015
cellular macromolecule catabolic process	GO:0044265	206	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.015
regulation of organelle organization	GO:0033043	289	0.015
positive regulation of cell development	GO:0010720	237	0.015	Mouse
organonitrogen compound catabolic process	GO:1901565	264	0.015
nucleoside phosphate catabolic process	GO:1901292	222	0.015
regulation of proteolysis	GO:0030162	164	0.015
regulation of protein processing	GO:0070613	96	0.015
multicellular organismal signaling	GO:0035637	91	0.015
purine ribonucleoside metabolic process	GO:0046128	241	0.015
oocyte development	GO:0048599	33	0.014
regulation of purine nucleotide metabolic process	GO:1900542	169	0.014
response to acid chemical	GO:0001101	111	0.014
peptide transport	GO:0015833	133	0.014
regulation of system process	GO:0044057	200	0.014	Mouse
female gamete generation	GO:0007292	74	0.014
vitamin metabolic process	GO:0006766	23	0.014
respiratory system development	GO:0060541	190	0.014
transmission of nerve impulse	GO:0019226	76	0.014
purine nucleoside metabolic process	GO:0042278	241	0.014
regulation of response to wounding	GO:1903034	189	0.014	Mouse
chromatin organization	GO:0006325	206	0.014
organ growth	GO:0035265	117	0.014
innate immune response	GO:0045087	157	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.013
circulatory system process	GO:0003013	197	0.013
negative regulation of reproductive process	GO:2000242	31	0.013
cell adhesion	GO:0007155	329	0.013	Mouse
axonogenesis	GO:0007409	274	0.013
isoprenoid metabolic process	GO:0006720	29	0.013
positive regulation of nucleotide catabolic process	GO:0030813	88	0.013
skin development	GO:0043588	220	0.013
fat cell differentiation	GO:0045444	160	0.013	Mouse
spermatid differentiation	GO:0048515	115	0.013
glycosyl compound catabolic process	GO:1901658	206	0.013
ribonucleoside metabolic process	GO:0009119	245	0.013
response to inorganic substance	GO:0010035	96	0.013
positive regulation of cell projection organization	GO:0031346	95	0.013
organic acid transport	GO:0015849	101	0.013
oocyte axis specification	GO:0007309	2	0.013
kidney epithelium development	GO:0072073	121	0.013	Mouse
oocyte differentiation	GO:0009994	35	0.013
single organism cell adhesion	GO:0098602	156	0.013
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.013
rab protein signal transduction	GO:0032482	1	0.012
purine nucleoside catabolic process	GO:0006152	205	0.012
regulation of cellular component biogenesis	GO:0044087	181	0.012	Mouse
synaptic transmission	GO:0007268	329	0.012	Mouse
glycoprotein biosynthetic process	GO:0009101	89	0.012
blood circulation	GO:0008015	195	0.012
regulation of nucleotide metabolic process	GO:0006140	169	0.012
negative regulation of cellular protein metabolic process	GO:0032269	247	0.012	Mouse
dna metabolic process	GO:0006259	303	0.012
striated muscle cell development	GO:0055002	125	0.012
blood vessel morphogenesis	GO:0048514	285	0.012
oocyte construction	GO:0007308	2	0.012
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.012
epithelial tube morphogenesis	GO:0060562	303	0.012
anatomical structure homeostasis	GO:0060249	145	0.012
neuron death	GO:0070997	154	0.012
cation homeostasis	GO:0055080	212	0.012
regulation of mapk cascade	GO:0043408	248	0.012	Mouse
lung development	GO:0030324	164	0.012
regulation of cellular response to stress	GO:0080135	159	0.012
inorganic ion transmembrane transport	GO:0098660	234	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.012
hematopoietic progenitor cell differentiation	GO:0002244	143	0.012
nucleotide catabolic process	GO:0009166	217	0.012
rho protein signal transduction	GO:0007266	32	0.012
regulation of cell projection organization	GO:0031344	206	0.012
neuronal action potential	GO:0019228	54	0.012
steroid metabolic process	GO:0008202	119	0.012
cytoplasmic transport	GO:0016482	234	0.011
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.011
positive regulation of neuron differentiation	GO:0045666	141	0.011
anion transmembrane transport	GO:0098656	71	0.011
nucleoside triphosphate metabolic process	GO:0009141	230	0.011
g protein coupled receptor signaling pathway	GO:0007186	243	0.011
oogenesis	GO:0048477	56	0.011
negative regulation of defense response	GO:0031348	77	0.011	Mouse
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.011
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.011
carbohydrate metabolic process	GO:0005975	230	0.011	Mouse
synapse organization	GO:0050808	125	0.011	Mouse
negative regulation of multi organism process	GO:0043901	68	0.011
regulation of hormone levels	GO:0010817	211	0.011
muscle cell differentiation	GO:0042692	261	0.011
telencephalon development	GO:0021537	186	0.011
gtp catabolic process	GO:0006184	143	0.011
regulation of homeostatic process	GO:0032844	182	0.011
skeletal muscle organ development	GO:0060538	163	0.011
purine nucleotide catabolic process	GO:0006195	211	0.011
muscle system process	GO:0003012	141	0.011
renal system development	GO:0072001	225	0.011	Mouse
single fertilization	GO:0007338	82	0.011
cellular amine metabolic process	GO:0044106	44	0.011
positive regulation of nucleoside metabolic process	GO:0045979	91	0.011
methylation	GO:0032259	134	0.011
response to radiation	GO:0009314	165	0.011
regulation of lymphocyte activation	GO:0051249	240	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.011
negative regulation of molecular function	GO:0044092	258	0.011	Mouse
response to lipopolysaccharide	GO:0032496	128	0.011
peptidyl amino acid modification	GO:0018193	336	0.010
regulation of protein maturation	GO:1903317	96	0.010
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.010
positive regulation of transferase activity	GO:0051347	167	0.010	Mouse
nucleoside triphosphate catabolic process	GO:0009143	205	0.010
t cell activation	GO:0042110	289	0.010
negative regulation of protein processing	GO:0010955	79	0.010
myeloid cell differentiation	GO:0030099	233	0.010
regulation of cell motility	GO:2000145	236	0.010	Mouse
divalent inorganic cation transport	GO:0072511	178	0.010
ribonucleotide catabolic process	GO:0009261	208	0.010
leukocyte migration	GO:0050900	124	0.010
regulation of cytokine production	GO:0001817	266	0.010
chromatin modification	GO:0016568	187	0.010
response to growth factor	GO:0070848	198	0.010
isoprenoid biosynthetic process	GO:0008299	9	0.010
regulation of epithelial cell proliferation	GO:0050678	141	0.010
rna processing	GO:0006396	105	0.010
mesonephric epithelium development	GO:0072163	94	0.010
cerebral cortex development	GO:0021987	86	0.010
regulation of t cell activation	GO:0050863	170	0.010
mapk cascade	GO:0000165	281	0.010	Mouse
cellular protein catabolic process	GO:0044257	155	0.010
posttranscriptional regulation of gene expression	GO:0010608	155	0.010

C1qtnf5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
retinal disease	DOID:5679	0.110
disease of anatomical entity	DOID:7	0.110
sensory system disease	DOID:0050155	0.110
eye disease	DOID:5614	0.110
nervous system disease	DOID:863	0.110
eye and adnexa disease	DOID:1492	0.110
disease of metabolism	DOID:0014667	0.025

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