Mus musculus

618 known processes

Bcl2

B-cell leukemia/lymphoma 2

(Aliases: C430015F12Rik,AW986256,Bcl-2,D630044D05Rik,D830018M01Rik)

Bcl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110111.000
Mouse
urogenital system developmentGO:00016552611.000
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686111.000
Mouse
release of cytochrome c from mitochondriaGO:0001836231.000
cellular response to gamma radiationGO:007148041.000
Mouse
mesonephric tubule developmentGO:0072164941.000
cellular process regulating host cell cycle in response to virusGO:006015431.000
Mouse
renal tubule developmentGO:0061326871.000
glomerulus developmentGO:0032835401.000
positive regulation of release of cytochrome c from mitochondriaGO:009020051.000
kidney developmentGO:00018222131.000
positive regulation of apoptotic process involved in mammary gland involutionGO:006005841.000
Mouse
nephron morphogenesisGO:0072028691.000
regulation of mitochondrion organizationGO:0010821271.000
Worm
nephron developmentGO:00720061091.000
nephron tubule morphogenesisGO:0072078681.000
spermatid differentiationGO:00485151150.999
Mouse
apoptotic process involved in embryonic digit morphogenesisGO:190226330.999
Mouse
kidney morphogenesisGO:0060993830.999
kidney epithelium developmentGO:00720731210.999
nephron tubule developmentGO:0072080840.999
positive regulation of apoptotic process involved in morphogenesisGO:190233940.998
Mouse
ureteric bud developmentGO:0001657940.998
morphogenesis of a branching structureGO:00017632030.998
regulation of release of cytochrome c from mitochondriaGO:0090199110.998
apoptotic process involved in mammary gland involutionGO:006005740.998
Mouse
morphogenesis of a branching epitheliumGO:00611381930.998
cellular response to radiationGO:0071478280.998
Mouse
negative regulation of protein phosphorylationGO:00019331260.997
Mouse
ureteric bud morphogenesisGO:0060675620.997
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome cGO:000863540.997
Mouse
alpha beta t cell differentiationGO:0046632690.997
mesonephros developmentGO:0001823970.997
apoptotic mitochondrial changesGO:0008637480.997
spermatogenesisGO:00072832840.997
Mouse
mesonephric epithelium developmentGO:0072163940.997
amine metabolic processGO:0009308450.996
mitochondrial fusionGO:000805390.996
Mouse Worm
muscle cell differentiationGO:00426922610.996
positive regulation of mitochondrion organizationGO:0010822170.996
Worm
negative regulation of protein metabolic processGO:00512482820.996
Zebrafish Mouse
mesenchymal cell differentiationGO:00487621070.996
mesenchyme developmentGO:00604851520.995
regulation of smooth muscle cell migrationGO:001491060.995
regulation of neuron differentiationGO:00456642810.995
branching involved in ureteric bud morphogenesisGO:0001658560.995
mesenchymal cell developmentGO:0014031930.994
cd8 positive alpha beta t cell lineage commitmentGO:004337510.994
myotube differentiationGO:00149021050.993
protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:000184440.993
Mouse
lymphocyte differentiationGO:00300982420.992
regulation of apoptotic signaling pathwayGO:20012331970.992
skin developmentGO:00435882200.992
regulation of membrane potentialGO:00423911920.990
ossificationGO:00015032160.990
stem cell developmentGO:00488642190.989
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.988
Mouse
positive regulation of nervous system developmentGO:00519622210.988
development of primary sexual characteristicsGO:00451371430.988
germ cell developmentGO:00072811850.987
formation of radial glial scaffoldsGO:002194340.987
positive regulation of glial cell proliferationGO:006025240.987
purine nucleotide metabolic processGO:00061633020.987
Worm
epithelial tube morphogenesisGO:00605623030.987
branching morphogenesis of an epithelial tubeGO:00487541590.987
muscle tissue developmentGO:00605373080.986
nephron epithelium morphogenesisGO:0072088680.986
extrinsic apoptotic signaling pathwayGO:00971911260.986
positive regulation of cell deathGO:00109422240.985
Mouse
multicellular organism growthGO:00352641610.984
negative regulation of osteoblast proliferationGO:003368940.983
negative regulation of fibroblast proliferationGO:0048147140.983
Mouse
odontogenesisGO:0042476780.983
Mouse
endoplasmic reticulum calcium ion homeostasisGO:0032469110.983
nephron epithelium developmentGO:0072009920.982
purine ribonucleoside triphosphate metabolic processGO:00092052200.982
Worm
renal system developmentGO:00720012250.981
single organism cell adhesionGO:00986021560.979
ribonucleotide metabolic processGO:00092592910.979
Worm
positive regulation of apoptotic processGO:00430652170.979
Mouse
apoptotic process involved in patterning of blood vesselsGO:190226260.977
Mouse
regulation of fibroblast proliferationGO:0048145340.977
Mouse
positive regulation of apoptotic signaling pathwayGO:2001235950.977
Mouse
mitochondrial outer membrane permeabilizationGO:0097345100.976
Mouse
male gamete generationGO:00482322850.976
Mouse
gtp catabolic processGO:00061841430.975
Worm
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337830.975
Mouse
cellular amino acid metabolic processGO:00065201030.975
regulation of developmental pigmentationGO:0048070140.974
membrane organizationGO:00610242450.974
negative regulation of cellular amino acid metabolic processGO:004576300.973
positive regulation of cell developmentGO:00107202370.973
glycosyl compound metabolic processGO:19016572460.972
Worm
regulation of endocytic recyclingGO:200113530.972
sphingolipid metabolic processGO:0006665450.972
Mouse
axonogenesisGO:00074092740.972
hair follicle developmentGO:0001942850.971
female sex differentiationGO:0046660840.971
apoptotic process involved in morphogenesisGO:0060561250.970
Mouse
digestive tract developmentGO:00485651900.970
metanephric tubule developmentGO:0072170180.968
apoptotic signaling pathwayGO:00971903060.968
positive regulation of b cell apoptotic processGO:000290440.968
Mouse
mammary gland morphogenesisGO:0060443540.967
Mouse
positive regulation of neuroepithelial cell differentiationGO:190291350.967
organ growthGO:00352651170.965
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.965
Human Mouse
lymphocyte proliferationGO:00466511640.964
Human Mouse
negative regulation of cellular amine metabolic processGO:003323910.964
regulation of osteoblast proliferationGO:0033688150.964
positive regulation of hydrolase activityGO:00513451480.964
Mouse Worm
negative regulation of cell proliferationGO:00082852960.963
positive regulation of peptidase activityGO:0010952490.963
Mouse
ovarian follicle developmentGO:0001541400.962
negative regulation of lymphocyte apoptotic processGO:0070229240.961
Mouse
b cell proliferationGO:0042100530.961
Human Mouse
regulation of cellular amine metabolic processGO:0033238200.960
metanephros developmentGO:0001656790.960
nucleoside triphosphate metabolic processGO:00091412300.958
Worm
skeletal muscle organ developmentGO:00605381630.958
negative regulation of apoptotic signaling pathwayGO:20012341040.958
positive regulation of mammary gland involutionGO:190352140.958
Mouse
regulation of epithelial cell proliferationGO:00506781410.957
Mouse
t cell activationGO:00421102890.957
negative regulation of phosphorus metabolic processGO:00105631840.957
Mouse
positive regulation of proteolysisGO:0045862850.955
Mouse
positive regulation of endocytic recyclingGO:200113720.954
sensory organ morphogenesisGO:00905962420.954
mesonephric tubule morphogenesisGO:0072171630.952
muscle cell migrationGO:0014812190.949
glycosyl compound catabolic processGO:19016582060.948
Worm
actin cytoskeleton organizationGO:00300362200.948
appendage morphogenesisGO:00351071490.948
Mouse
smooth muscle cell migrationGO:0014909100.946
gtp metabolic processGO:00460391440.945
Worm
epidermis developmentGO:00085441870.943
syncytium formation by plasma membrane fusionGO:0000768420.941
regulation of purine nucleotide metabolic processGO:19005421690.941
Worm
cochlear nucleus developmentGO:002174740.939
negative regulation of b cell apoptotic processGO:000290370.939
Mouse
positive regulation of programmed cell deathGO:00430682180.938
Mouse
muscle cell developmentGO:00550011330.937
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.937
Mouse
hypothalamus developmentGO:0021854160.937
Mouse
gland developmentGO:00487323300.936
leukocyte differentiationGO:00025213420.934
pallium developmentGO:00215431200.934
Mouse
regulation of peptidase activityGO:0052547960.933
Zebrafish Mouse
regulation of cellular ketone metabolic processGO:0010565660.933
b cell differentiationGO:0030183780.933
ear developmentGO:00435832000.933
regulation of nucleotide metabolic processGO:00061401690.930
Worm
regulation of melanocyte differentiationGO:004563470.928
cell type specific apoptotic processGO:00972852680.927
positive regulation of pigment cell differentiationGO:005094250.926
apoptotic process involved in developmentGO:1902742280.925
Mouse
nucleoside catabolic processGO:00091642060.925
Worm
activation of cysteine type endopeptidase activityGO:0097202270.924
Mouse
post embryonic organ developmentGO:0048569170.923
Mouse
positive regulation of melanocyte differentiationGO:004563650.923
purine nucleotide catabolic processGO:00061952110.921
Worm
development of primary female sexual characteristicsGO:0046545730.920
neuron migrationGO:00017641220.918
Mouse
digestive system developmentGO:00551232000.918
negative regulation of protein modification processGO:00314001630.918
Mouse
regulation of organ morphogenesisGO:20000271440.918
regulation of cellular catabolic processGO:00313292420.918
Worm
negative regulation of cellular protein metabolic processGO:00322692470.918
Zebrafish Mouse
cellular response to acid chemicalGO:0071229680.916
Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.915
Worm
response to organic cyclic compoundGO:00140701980.915
renal tubule morphogenesisGO:0061333720.915
diencephalon developmentGO:0021536630.913
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.913
Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056390.912
Mouse
lymphocyte homeostasisGO:0002260640.911
response to endoplasmic reticulum stressGO:0034976530.911
Human Mouse
b cell activationGO:00421131610.911
cation transportGO:00068123990.909
regulation of bmp signaling pathwayGO:0030510600.908
regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006141820.907
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.906
Mouse
alpha beta t cell activationGO:0046631910.906
positive regulation of protein oligomerizationGO:003246140.906
neuron apoptotic processGO:00514021420.905
hematopoietic progenitor cell differentiationGO:00022441430.904
regulation of ion transportGO:00432692150.903
purine nucleoside catabolic processGO:00061522050.903
Worm
positive regulation of leukocyte apoptotic processGO:2000108210.902
Mouse
regulation of cysteine type endopeptidase activityGO:2000116650.902
Zebrafish Mouse
stem cell differentiationGO:00488632680.900
maintenance of locationGO:0051235890.899
ribonucleoside triphosphate catabolic processGO:00092031990.899
Worm
regulation of striated muscle cell differentiationGO:0051153810.897
cell growthGO:00160491300.897
axon guidanceGO:00074111410.897
t cell apoptotic processGO:0070231390.896
Mouse
neuronal action potentialGO:0019228540.895
digestive tract morphogenesisGO:00485461470.895
positive regulation of neuron maturationGO:001404220.895
protein oligomerizationGO:0051259670.895
Mouse
positive regulation of bmp signaling pathwayGO:0030513230.892
regulation of mitotic cell cycle phase transitionGO:1901990730.892
cytosolic calcium ion transportGO:0060401480.890
metanephric glomerular mesangium developmentGO:007222330.889
regulation of protein oligomerizationGO:003245940.889
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337630.888
Mouse
positive regulation of nucleotide catabolic processGO:0030813880.887
Worm
cellular response to nutrient levelsGO:0031669640.887
genitalia developmentGO:0048806370.887
Mouse
male gonad developmentGO:0008584880.886
striated muscle tissue developmentGO:00147062930.883
regulation of myotube differentiationGO:0010830620.883
establishment of protein localization to organelleGO:00725941180.883
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.882
Human Mouse
ribose phosphate metabolic processGO:00196932910.881
Worm
oogenesisGO:0048477560.880
positive regulation of myotube differentiationGO:0010831240.879
skeletal muscle fiber developmentGO:0048741580.879
retina development in camera type eyeGO:00600411190.878
Mouse
thymocyte apoptotic processGO:0070242190.874
Mouse
skeletal system developmentGO:00015013560.874
t cell differentiation in thymusGO:0033077770.874
positive regulation of growthGO:00459271040.873
lipid homeostasisGO:0055088630.872
hair cycleGO:0042633900.871
rhythmic processGO:00485111740.870
guanosine containing compound catabolic processGO:19010691440.870
Worm
eye photoreceptor cell differentiationGO:0001754410.869
gonad developmentGO:00084061410.869
response to oxygen levelsGO:0070482620.867
negative regulation of growthGO:0045926990.866
organelle fusionGO:0048284280.865
Mouse Worm
response to ionizing radiationGO:0010212420.863
nucleobase containing small molecule metabolic processGO:00550863520.863
Worm
activation of immune responseGO:00022531380.863
Human
regulation of cell migrationGO:00303342190.862
regulation of nitrogen utilizationGO:000680820.862
cell substrate adhesionGO:00315891300.861
regulation of mitochondrial membrane permeabilityGO:0046902170.857
embryonic digit morphogenesisGO:0042733560.854
Mouse
regulation of protein stabilityGO:0031647520.851
t helper cell differentiationGO:0042093280.851
nucleoside phosphate metabolic processGO:00067533380.849
Worm
response to nutrient levelsGO:00316671090.848
regulation of dna templated transcription in response to stressGO:004362090.847
divalent inorganic cation homeostasisGO:00725071380.847
mitochondrial membrane organizationGO:0007006260.847
immune effector processGO:00022523210.847
Human
purine ribonucleoside metabolic processGO:00461282410.845
Worm
protein maturationGO:00516041760.845
Zebrafish Mouse
post embryonic eye morphogenesisGO:004805040.844
Mouse
mammary gland epithelial cell proliferationGO:0033598240.841
Mouse
regulation of membrane permeabilityGO:0090559180.841
nucleotide catabolic processGO:00091662170.840
Worm
connective tissue developmentGO:00614481790.840
positive regulation of gtp catabolic processGO:0033126850.840
Worm
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.839
regulation of lymphocyte apoptotic processGO:0070228410.839
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.832
positive regulation of nucleoside metabolic processGO:0045979910.831
Worm
hindbrain developmentGO:00309021280.830
positive regulation of cell maturationGO:190343140.830
cell adhesionGO:00071553290.827
regulation of hydrolase activityGO:00513362460.827
Zebrafish Mouse Worm
neuron intrinsic apoptotic signaling pathway in response to oxidative stressGO:003648030.827
Mouse
nucleotide metabolic processGO:00091173320.827
Worm
neural nucleus developmentGO:0048857220.826
developmental programmed cell deathGO:0010623410.826
signal transduction by p53 class mediatorGO:0072331510.823
Mouse
response to uv bGO:001022450.823
regulation of killing of cells of other organismGO:005170940.822
peptidyl amino acid modificationGO:00181933360.821
carbohydrate metabolic processGO:00059752300.821
spleen developmentGO:0048536390.820
response to peptide hormoneGO:00434341270.819
Rat
modulation by virus of host morphology or physiologyGO:001904830.817
muscle fiber developmentGO:0048747760.816
protein localization to mitochondrionGO:0070585150.815
Mouse
positive regulation of developmental pigmentationGO:004808760.815
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.814
Mouse
nucleoside metabolic processGO:00091162460.814
Worm
bmp signaling pathwayGO:0030509930.812
multicellular organismal signalingGO:0035637910.810
positive regulation of lymphocyte apoptotic processGO:0070230130.809
Mouse
positive regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001241100.807
Mouse
telencephalon developmentGO:00215371860.806
Mouse
negative regulation of bmp signaling pathwayGO:0030514350.802
negative regulation of cell growthGO:0030308440.802
peptidyl tyrosine phosphorylationGO:00181081430.801
regulation of gtp catabolic processGO:00331241130.800
Worm
dephosphorylationGO:00163111290.799
regulation of pigment cell differentiationGO:005093270.798
ribonucleoside triphosphate metabolic processGO:00091992200.797
Worm
regulation of skeletal muscle fiber developmentGO:0048742360.796
response to organonitrogen compoundGO:00102432460.790
Human Mouse Rat
glial cell apoptotic processGO:003434930.789
Rat
purine ribonucleotide metabolic processGO:00091502900.781
Worm
organic hydroxy compound metabolic processGO:19016152030.777
cellular macromolecule catabolic processGO:00442652060.777
negative regulation of intracellular transportGO:0032387380.777
cellular response to extracellular stimulusGO:0031668810.777
pigmentationGO:0043473710.777
protein localization to membraneGO:00726571080.776
Mouse
cranial nerve structural organizationGO:0021604130.776
regulation of muscle tissue developmentGO:1901861970.775
metanephric nephron epithelium developmentGO:0072243190.775
regulation of protein targetingGO:1903533610.773
gliogenesisGO:00420631410.769
Rat
myeloid cell homeostasisGO:00022621140.766
Mouse
carbon catabolite activation of transcriptionGO:004599140.766
neuron maturationGO:0042551290.764
positive regulation of nucleotide metabolic processGO:00459811140.764
Worm
negative regulation of immune system processGO:00026832090.763
establishment of protein localization to membraneGO:0090150540.759
Mouse
positive regulation of mitochondrial membrane permeabilityGO:0035794120.758
Mouse
biomineral tissue developmentGO:0031214640.758
regulation of proteolysisGO:00301621640.758
Zebrafish Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.757
camera type eye developmentGO:00430102660.755
Mouse
t cell differentiationGO:00302171740.754
lymphocyte apoptotic processGO:0070227540.753
Mouse
immune response activating signal transductionGO:00027571160.749
Human
renal filtration cell differentiationGO:0061318100.749
regulation of cellular component biogenesisGO:00440871810.748
signal transduction in absence of ligandGO:0038034550.747
regulation of cell cycleGO:00517262810.746
antigen receptor mediated signaling pathwayGO:0050851640.745
Human
embryonic limb morphogenesisGO:00303261260.744
Mouse
cellular nitrogen compound catabolic processGO:00442702800.741
Worm
kidney vasculature developmentGO:0061440150.740
cellular calcium ion homeostasisGO:00068741190.738
meiotic cell cycleGO:00513211220.738
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.737
Zebrafish Mouse
post embryonic organ morphogenesisGO:004856380.736
Mouse
regulation of cell cycle processGO:00105641600.735
alpha beta t cell differentiation involved in immune responseGO:0002293300.735
regulation of actin cytoskeleton organizationGO:0032956840.731
mesoderm developmentGO:00074981000.729
viral processGO:0016032410.724
single organismal cell cell adhesionGO:00163371310.723
ribonucleoside catabolic processGO:00424542060.723
Worm
protein targetingGO:00066051430.722
myeloid cell apoptotic processGO:0033028220.722
zymogen activationGO:0031638410.721
Mouse
regulation of tissue remodelingGO:0034103380.721
Mouse
vesicle organizationGO:0016050600.720
regulation of nucleotide catabolic processGO:00308111220.719
Worm
peptidyl serine modificationGO:0018209830.717
development of primary male sexual characteristicsGO:0046546880.715
cell substrate junction assemblyGO:0007044240.715
purine containing compound metabolic processGO:00725213110.714
Worm
response to alkaloidGO:0043279340.713
Human Mouse Rat
negative regulation of mesenchymal cell apoptotic process involved in metanephros developmentGO:190021240.711
female gamete generationGO:0007292740.709
regulation of endothelial cell migrationGO:0010594220.707
carbohydrate derivative biosynthetic processGO:19011371830.704
leukocyte proliferationGO:00706611720.703
Human Mouse
cellular protein catabolic processGO:00442571550.703
odontogenesis of dentin containing toothGO:0042475660.703
Mouse
pronephric nephron developmentGO:003901910.702
response to radiationGO:00093141650.700
ribonucleotide catabolic processGO:00092612080.698
Worm
ovulation cycleGO:0042698590.697
positive regulation of purine nucleotide catabolic processGO:0033123880.696
Worm
negative regulation of peptidyl serine phosphorylationGO:0033137100.696
Mouse
membrane fusionGO:0061025380.693
Mouse Worm
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.692
Mouse
leukocyte apoptotic processGO:0071887710.689
Mouse
cerebral cortex developmentGO:0021987860.688
Mouse
b cell receptor signaling pathwayGO:0050853200.686
Human
regulation of t cell differentiationGO:0045580830.686
regulation of bindingGO:00510981110.686
Human
epithelial cell proliferationGO:00506731740.684
Mouse
b cell homeostatic proliferationGO:000235820.684
Mouse
organelle fissionGO:00482851700.681
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.680
regulation of protein localizationGO:00328802310.678
positive regulation of killing of cells of other organismGO:005171230.674
male sex differentiationGO:00466611090.673
limb morphogenesisGO:00351081490.671
Mouse
negative regulation of calcium ion transportGO:005192690.671
forebrain developmentGO:00309003020.664
Mouse
regulation of protein complex assemblyGO:0043254830.663
positive regulation of calcium ion transport into cytosolGO:001052490.661
Mouse
b cell homeostasisGO:0001782340.660
t cell proliferationGO:00420981200.660
Mouse
regulation of neuron projection developmentGO:00109751690.656
cellular response to decreased oxygen levelsGO:0036294180.653
muscle cell proliferationGO:0033002520.652
metencephalon developmentGO:0022037890.649
angiogenesisGO:00015252010.649
Mouse
blood vessel morphogenesisGO:00485142850.648
Mouse
release of sequestered calcium ion into cytosolGO:0051209420.648
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858240.647
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.647
cardiac right atrium morphogenesisGO:000321330.647
regulation of myeloid cell apoptotic processGO:0033032190.646
cellular response to glucose starvationGO:004214950.646
proteolysis involved in cellular protein catabolic processGO:00516031470.646
positive regulation of neuron deathGO:1901216280.643
Mouse
mitochondrial transportGO:0006839360.642
carbohydrate homeostasisGO:00335001280.641
positive regulation of protein modification processGO:00314012990.638
formation of primary germ layerGO:0001704770.637
regulation of mitochondrial membrane permeability involved in programmed necrotic cell deathGO:190244520.636
Mouse
actin filament organizationGO:00070151130.636
t cell activation involved in immune responseGO:0002286430.632
positive regulation of cellular response to oxidative stressGO:190040960.632
Mouse
respiratory system developmentGO:00605411900.632
positive regulation of organelle organizationGO:00106381280.631
Worm
regulation of peptidyl serine phosphorylationGO:0033135390.631
positive regulation of peptidyl serine phosphorylationGO:0033138250.628
negative regulation of cell migrationGO:0030336590.625
metanephric glomerular mesangial cell proliferation involved in metanephros developmentGO:007226230.623
synaptic transmissionGO:00072683290.621
melanin metabolic processGO:0006582120.619
positive regulation of alpha beta t cell differentiationGO:0046638280.618
purine containing compound catabolic processGO:00725232130.618
Worm
cellular response to external stimulusGO:0071496880.613
multicellular organismal response to stressGO:0033555620.613
negative regulation of cellular component organizationGO:00511291940.608
divalent metal ion transportGO:00708381720.606
negative regulation of cytoplasmic transportGO:1903650290.605
regulation of cell adhesionGO:00301551540.603
positive regulation of interleukin 5 secretionGO:200066410.602
thymus developmentGO:0048538410.602
positive regulation of oxidative stress induced neuron deathGO:190322330.601
Mouse
response to mycotoxinGO:001004610.601
Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.601
Worm
negative regulation of ossificationGO:0030279490.600
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.598
Human Mouse
epithelium migrationGO:0090132630.597
pigment metabolic processGO:0042440320.597
g1 s transition of mitotic cell cycleGO:0000082570.596
cellular response to abiotic stimulusGO:0071214560.595
Mouse
peptidyl serine phosphorylationGO:0018105740.593
b cell selectionGO:000233930.592
Mouse
positive regulation of gliogenesisGO:0014015270.590
regulation of cellular amino acid metabolic processGO:000652150.589
mammary gland epithelium developmentGO:0061180650.588
Mouse
epithelial cell developmentGO:00020641590.584
regulation of cell cycle phase transitionGO:1901987770.583
negative regulation of molecular functionGO:00440922580.580
Zebrafish
protein localization to nucleusGO:00345041210.579
regulation of transcription from rna polymerase iii promoterGO:000635920.576
ribonucleoside metabolic processGO:00091192450.576
Worm
female gonad developmentGO:0008585710.575
regulation of neuron deathGO:19012141340.575
positive regulation of striated muscle cell differentiationGO:0051155350.575
positive regulation of neuron apoptotic processGO:0043525250.574
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.573
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.573
negative regulation of fat cell differentiationGO:0045599360.572
regulation of metanephros developmentGO:0072215150.572
aromatic compound catabolic processGO:00194392860.572
Worm
interspecies interaction between organismsGO:0044419830.569
vagina developmentGO:0060068110.567
Mouse
regulation of axon extensionGO:0030516430.566
mesangial cell differentiationGO:007200740.561
adherens junction organizationGO:0034332280.556
negative regulation of neuron deathGO:1901215980.554
positive regulation of cell cycleGO:0045787920.554
positive regulation of smooth muscle cell migrationGO:001491140.552
positive regulation of neuron differentiationGO:00456661410.552
b cell apoptotic processGO:0001783190.552
Mouse
purine ribonucleoside catabolic processGO:00461302050.551
Worm
response to starvationGO:0042594650.546
oligodendrocyte differentiationGO:0048709530.545
Rat
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.544
regulation of nucleoside metabolic processGO:00091181300.543
Worm
proteasomal protein catabolic processGO:0010498980.542
liposaccharide metabolic processGO:1903509270.540
Mouse
negative regulation of endoplasmic reticulum calcium ion concentrationGO:003247130.540
Mouse
sertoli cell proliferationGO:006001150.537
Mouse
sequestering of calcium ionGO:0051208180.537
response to hypoxiaGO:0001666580.535
small gtpase mediated signal transductionGO:0007264970.535
leukocyte activation involved in immune responseGO:00023661260.533
renal system vasculature developmentGO:0061437150.532
positive regulation of t cell differentiationGO:0045582520.531
metanephric nephron developmentGO:0072210340.530
negative regulation of cell motilityGO:2000146610.528
negative regulation of calcium ion transport into cytosolGO:001052320.528
somitogenesisGO:0001756690.527

Bcl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.996
cancerDOID:16200.974
phaeochromocytomaDOID:005077100.752
cell type benign neoplasmDOID:006008400.752
benign neoplasmDOID:006007200.752
disease of anatomical entityDOID:700.655
gastrointestinal system diseaseDOID:7700.655
urinary system diseaseDOID:1800.626
kidney cancerDOID:26300.545
urinary system cancerDOID:399600.545
organ system cancerDOID:005068600.545