| activation of adenylate cyclase activity | GO:0007190 | 4 | 0.666 | Yeast |
| photoreceptor cell morphogenesis | GO:0008594 | 3 | 0.406 | Fly |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.321 | Mouse |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.309 | Yeast Mouse Worm Fly |
| gtp metabolic process | GO:0046039 | 144 | 0.291 | Yeast Mouse Worm Fly |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.270 | Yeast Mouse Worm Fly |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.238 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.225 | Mouse |
| regulation of transcription by galactose | GO:0000409 | 1 | 0.210 | Yeast |
| carbon catabolite regulation of transcription | GO:0045990 | 4 | 0.203 | Yeast |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.201 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.199 | Yeast Mouse Worm Fly |
| oocyte construction | GO:0007308 | 2 | 0.197 | Fly |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.185 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.179 | |
| positive regulation of transcription by galactose | GO:0000411 | 1 | 0.155 | Yeast |
| organelle assembly | GO:0070925 | 177 | 0.155 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.151 | Mouse |
| positive regulation of camp metabolic process | GO:0030816 | 19 | 0.142 | Yeast |
| regulation of lyase activity | GO:0051339 | 13 | 0.138 | Yeast |
| regulation of cell cycle | GO:0051726 | 281 | 0.136 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.136 | Yeast Mouse Worm Fly |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.134 | Mouse |
| cellular amine metabolic process | GO:0044106 | 44 | 0.133 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.130 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.129 | Yeast Mouse Worm Fly |
| striated muscle tissue development | GO:0014706 | 293 | 0.126 | |
| protein complex disassembly | GO:0043241 | 40 | 0.122 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.116 | Yeast Mouse Worm Fly |
| cell growth | GO:0016049 | 130 | 0.112 | Yeast Fly |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.108 | Yeast Mouse Worm Fly |
| regulation of organelle organization | GO:0033043 | 289 | 0.104 | |
| adenylate cyclase activating g protein coupled receptor signaling pathway | GO:0007189 | 30 | 0.101 | Yeast |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.100 | Yeast |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.099 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.098 | Yeast Mouse Worm Fly |
| protein import | GO:0017038 | 101 | 0.097 | Fly |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.097 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.096 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.094 | Yeast Mouse Worm Fly |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.089 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.089 | |
| regulation of protein stability | GO:0031647 | 52 | 0.088 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.087 | Yeast Mouse Worm Fly |
| nucleotide metabolic process | GO:0009117 | 332 | 0.086 | Yeast Mouse Worm Fly |
| mapk cascade | GO:0000165 | 281 | 0.086 | Fly |
| carbon catabolite activation of transcription | GO:0045991 | 4 | 0.085 | Yeast |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.084 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.084 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.083 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.081 | Fly |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.080 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.079 | Yeast Mouse Worm Fly |
| purine nucleotide biosynthetic process | GO:0006164 | 65 | 0.076 | Yeast |
| cell fate commitment | GO:0045165 | 210 | 0.076 | Worm Fly |
| purine containing compound biosynthetic process | GO:0072522 | 70 | 0.075 | Yeast |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.074 | Yeast Mouse Worm Fly |
| central nervous system neuron differentiation | GO:0021953 | 162 | 0.074 | |
| adenylate cyclase modulating g protein coupled receptor signaling pathway | GO:0007188 | 54 | 0.073 | Yeast |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.073 | Worm |
| regulation of cell projection organization | GO:0031344 | 206 | 0.073 | Worm |
| regulation of cell adhesion | GO:0030155 | 154 | 0.072 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.072 | |
| regulation of cell growth | GO:0001558 | 91 | 0.071 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.070 | |
| cyclic nucleotide biosynthetic process | GO:0009190 | 44 | 0.068 | Yeast |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.068 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.068 | Yeast Mouse Worm Fly |
| mitotic cell cycle | GO:0000278 | 195 | 0.066 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.066 | Yeast Mouse Worm Fly |
| protein autophosphorylation | GO:0046777 | 61 | 0.065 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.065 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.065 | |
| limb development | GO:0060173 | 166 | 0.064 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.064 | |
| response to growth factor | GO:0070848 | 198 | 0.064 | |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.064 | Fly |
| microtubule based process | GO:0007017 | 236 | 0.063 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.063 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.062 | Fly |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.062 | Yeast Mouse Worm Fly |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.061 | Yeast Mouse Worm Fly |
| regulation of cell cycle process | GO:0010564 | 160 | 0.061 | |
| ameboidal type cell migration | GO:0001667 | 128 | 0.060 | Fly |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.060 | |
| chemotaxis | GO:0006935 | 247 | 0.059 | |
| regulation of cyclic nucleotide biosynthetic process | GO:0030802 | 31 | 0.059 | Yeast |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.059 | Mouse |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.058 | Yeast Mouse Worm Fly |
| wound healing | GO:0042060 | 157 | 0.058 | |
| positive regulation of synaptic growth at neuromuscular junction | GO:0045887 | 1 | 0.057 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.057 | Yeast Mouse Worm Fly |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.057 | Fly |
| amine metabolic process | GO:0009308 | 45 | 0.056 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.056 | Yeast Mouse Worm Fly |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.056 | Yeast |
| cell substrate adhesion | GO:0031589 | 130 | 0.056 | |
| negative regulation of protein depolymerization | GO:1901880 | 21 | 0.056 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.056 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.055 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.054 | Fly |
| spermatid differentiation | GO:0048515 | 115 | 0.054 | |
| positive regulation of rac protein signal transduction | GO:0035022 | 1 | 0.054 | Mouse |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.053 | Yeast Mouse Worm Fly |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.053 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.053 | |
| transmembrane transport | GO:0055085 | 412 | 0.053 | |
| regulation of neuron death | GO:1901214 | 134 | 0.053 | Mouse |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.051 | Yeast Mouse Worm Fly |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.051 | Yeast Mouse Worm Fly |
| developmental maturation | GO:0021700 | 193 | 0.051 | Fly |
| regulation of protein localization | GO:0032880 | 231 | 0.051 | Yeast |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.050 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.050 | Fly |
| cation transmembrane transport | GO:0098655 | 266 | 0.050 | |
| multicellular organism growth | GO:0035264 | 161 | 0.049 | Fly |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.049 | Yeast Mouse Worm Fly |
| regulation of nucleotide biosynthetic process | GO:0030808 | 34 | 0.048 | Yeast |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.048 | |
| nuclear transport | GO:0051169 | 139 | 0.048 | Fly |
| spermatogenesis | GO:0007283 | 284 | 0.047 | |
| exocytosis | GO:0006887 | 121 | 0.047 | Mouse |
| intracellular protein transport | GO:0006886 | 204 | 0.047 | Fly |
| positive regulation of cyclase activity | GO:0031281 | 11 | 0.047 | Yeast |
| cell division | GO:0051301 | 120 | 0.047 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.047 | Fly |
| cyclic purine nucleotide metabolic process | GO:0052652 | 43 | 0.046 | Yeast |
| cellular protein complex assembly | GO:0043623 | 116 | 0.046 | |
| cognition | GO:0050890 | 149 | 0.045 | Mouse |
| developmental cell growth | GO:0048588 | 84 | 0.045 | Fly |
| regulation of cyclase activity | GO:0031279 | 13 | 0.044 | Yeast |
| regulation of cell motility | GO:2000145 | 236 | 0.043 | Mouse |
| response to light stimulus | GO:0009416 | 135 | 0.043 | Mouse |
| camp biosynthetic process | GO:0006171 | 31 | 0.043 | Yeast |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.043 | Mouse |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.042 | Yeast Mouse Worm Fly |
| gliogenesis | GO:0042063 | 141 | 0.042 | Fly |
| cellular protein complex disassembly | GO:0043624 | 36 | 0.041 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.041 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.041 | |
| protein localization to organelle | GO:0033365 | 185 | 0.041 | Fly |
| appendage development | GO:0048736 | 166 | 0.040 | Fly |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.040 | Yeast Mouse Worm Fly |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.040 | Yeast Mouse Worm Fly |
| regulation of homeostatic process | GO:0032844 | 182 | 0.040 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.039 | |
| cell maturation | GO:0048469 | 127 | 0.039 | Fly |
| male gamete generation | GO:0048232 | 285 | 0.039 | |
| intermediate filament based process | GO:0045103 | 27 | 0.038 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.038 | Yeast Mouse Worm Fly |
| regulation of rap gtpase activity | GO:0032317 | 6 | 0.038 | Worm |
| arp2 3 complex mediated actin nucleation | GO:0034314 | 3 | 0.038 | |
| axon guidance | GO:0007411 | 141 | 0.037 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.037 | Yeast |
| ribonucleotide biosynthetic process | GO:0009260 | 59 | 0.037 | Yeast |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.037 | Yeast Mouse Worm Fly |
| macromolecule catabolic process | GO:0009057 | 281 | 0.037 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.037 | |
| terminal button organization | GO:0072553 | 3 | 0.037 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.037 | |
| regulation of adenylate cyclase activity | GO:0045761 | 10 | 0.036 | Yeast |
| protein depolymerization | GO:0051261 | 34 | 0.036 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.036 | |
| innate immune response | GO:0045087 | 157 | 0.036 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.036 | |
| oocyte axis specification | GO:0007309 | 2 | 0.036 | Fly |
| cellular homeostasis | GO:0019725 | 240 | 0.035 | |
| nuclear division | GO:0000280 | 158 | 0.035 | |
| regulation of exit from mitosis | GO:0007096 | 1 | 0.035 | |
| genetic imprinting | GO:0071514 | 27 | 0.034 | |
| neuron projection guidance | GO:0097485 | 141 | 0.034 | |
| axonogenesis | GO:0007409 | 274 | 0.034 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.034 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.034 | |
| neuron death | GO:0070997 | 154 | 0.034 | Mouse |
| protein ubiquitination | GO:0016567 | 171 | 0.034 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.034 | Mouse |
| nitrogen compound transport | GO:0071705 | 271 | 0.034 | |
| gland development | GO:0048732 | 330 | 0.033 | |
| positive regulation of cell morphogenesis involved in differentiation | GO:0010770 | 72 | 0.033 | |
| actin filament organization | GO:0007015 | 113 | 0.033 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.033 | |
| positive regulation of monooxygenase activity | GO:0032770 | 2 | 0.033 | |
| regulation of cyclin dependent protein serine threonine kinase activity | GO:0000079 | 16 | 0.033 | |
| regulation of camp biosynthetic process | GO:0030817 | 25 | 0.033 | Yeast |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.033 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.032 | |
| protein polymerization | GO:0051258 | 57 | 0.032 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.032 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.032 | Yeast Mouse Worm Fly |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.032 | |
| chromosome segregation | GO:0007059 | 48 | 0.032 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.032 | |
| muscle tissue development | GO:0060537 | 308 | 0.032 | |
| ribose phosphate biosynthetic process | GO:0046390 | 59 | 0.032 | Yeast |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.032 | |
| regulation of protein depolymerization | GO:1901879 | 26 | 0.031 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.031 | Fly |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.031 | Yeast Mouse Worm Fly |
| microtubule based movement | GO:0007018 | 84 | 0.031 | |
| regulation of protein complex disassembly | GO:0043244 | 28 | 0.031 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.031 | |
| muscle system process | GO:0003012 | 141 | 0.030 | |
| dna modification | GO:0006304 | 50 | 0.030 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.030 | |
| translation | GO:0006412 | 93 | 0.030 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.030 | |
| regulation of substrate adhesion dependent cell spreading | GO:1900024 | 12 | 0.030 | |
| response to nutrient levels | GO:0031667 | 109 | 0.029 | Yeast Fly |
| positive regulation of cytoskeleton organization | GO:0051495 | 49 | 0.029 | |
| macromolecular complex disassembly | GO:0032984 | 43 | 0.029 | |
| synaptic transmission | GO:0007268 | 329 | 0.029 | Mouse |
| mrna metabolic process | GO:0016071 | 84 | 0.029 | |
| regulation of cell substrate adhesion | GO:0010810 | 73 | 0.029 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.028 | Yeast Mouse Worm Fly |
| glycerophospholipid biosynthetic process | GO:0046474 | 32 | 0.028 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.028 | Fly |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.028 | Fly |
| sensory perception | GO:0007600 | 245 | 0.028 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.028 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.028 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.028 | Fly |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.028 | Yeast Mouse Worm Fly |
| regulation of cyclic nucleotide metabolic process | GO:0030799 | 40 | 0.027 | Yeast |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.027 | Mouse |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.027 | Fly |
| positive regulation of dendrite development | GO:1900006 | 21 | 0.027 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.027 | |
| hair follicle development | GO:0001942 | 85 | 0.027 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.027 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 36 | 0.027 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.027 | |
| mitochondrion distribution | GO:0048311 | 4 | 0.027 | |
| regulation of exocytosis | GO:0017157 | 61 | 0.027 | Mouse |
| protein targeting | GO:0006605 | 143 | 0.027 | Fly |
| regulation of camp metabolic process | GO:0030814 | 30 | 0.027 | Yeast |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.027 | Fly |
| organelle localization | GO:0051640 | 179 | 0.027 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.026 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.026 | |
| phagocytosis | GO:0006909 | 66 | 0.026 | |
| dna alkylation | GO:0006305 | 43 | 0.026 | |
| tissue homeostasis | GO:0001894 | 115 | 0.026 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.026 | |
| gonad morphogenesis | GO:0035262 | 1 | 0.026 | |
| organelle fission | GO:0048285 | 170 | 0.026 | |
| regulation of microtubule based process | GO:0032886 | 52 | 0.025 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.025 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.025 | Yeast Fly |
| barbed end actin filament capping | GO:0051016 | 6 | 0.025 | |
| action potential | GO:0001508 | 78 | 0.025 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.025 | |
| establishment or maintenance of microtubule cytoskeleton polarity | GO:0030951 | 1 | 0.025 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.025 | |
| positive regulation of cyclic nucleotide biosynthetic process | GO:0030804 | 24 | 0.024 | Yeast |
| regulation of translation | GO:0006417 | 71 | 0.024 | |
| secretory granule organization | GO:0033363 | 20 | 0.024 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.024 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.024 | |
| learning | GO:0007612 | 98 | 0.024 | Mouse |
| glycerolipid biosynthetic process | GO:0045017 | 50 | 0.024 | |
| dna metabolic process | GO:0006259 | 303 | 0.024 | |
| phospholipid biosynthetic process | GO:0008654 | 36 | 0.024 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.024 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.023 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.023 | Mouse |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.023 | |
| neuronal action potential | GO:0019228 | 54 | 0.023 | |
| negative regulation of growth | GO:0045926 | 99 | 0.023 | |
| camp metabolic process | GO:0046058 | 40 | 0.023 | Yeast |
| circulatory system process | GO:0003013 | 197 | 0.023 | |
| developmental growth involved in morphogenesis | GO:0060560 | 138 | 0.023 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.023 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.023 | Yeast Mouse Worm Fly |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.023 | |
| camera type eye development | GO:0043010 | 266 | 0.022 | |
| regulation of secretion | GO:0051046 | 274 | 0.022 | Mouse |
| purine ribonucleotide biosynthetic process | GO:0009152 | 59 | 0.022 | Yeast |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.022 | Mouse Worm |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.022 | |
| neuron projection extension | GO:1990138 | 64 | 0.022 | |
| forebrain development | GO:0030900 | 302 | 0.022 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.022 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.022 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.022 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.022 | |
| skeletal system development | GO:0001501 | 356 | 0.022 | |
| visual learning | GO:0008542 | 44 | 0.022 | Mouse |
| regulation of cytokine production | GO:0001817 | 266 | 0.022 | |
| response to insulin | GO:0032868 | 100 | 0.022 | |
| regulation of actin filament polymerization | GO:0030833 | 38 | 0.021 | |
| regulation of purine nucleotide biosynthetic process | GO:1900371 | 34 | 0.021 | Yeast |
| meiotic cell cycle process | GO:1903046 | 77 | 0.021 | Yeast |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 82 | 0.021 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.021 | Worm |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.021 | Yeast Mouse Worm Fly |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.021 | Yeast |
| skeletal muscle organ development | GO:0060538 | 163 | 0.021 | |
| formation of organ boundary | GO:0010160 | 1 | 0.021 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.021 | Yeast Worm |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.021 | |
| negative regulation of protein complex disassembly | GO:0043242 | 22 | 0.021 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.021 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.021 | Yeast Worm |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.021 | |
| negative regulation of fibroblast apoptotic process | GO:2000270 | 6 | 0.020 | |
| regulation of cell migration | GO:0030334 | 219 | 0.020 | Mouse |
| endomembrane system organization | GO:0010256 | 147 | 0.020 | |
| actin filament polymerization | GO:0030041 | 44 | 0.020 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.020 | Mouse |
| membrane organization | GO:0061024 | 245 | 0.020 | |
| intermediate filament cytoskeleton organization | GO:0045104 | 26 | 0.020 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.020 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.020 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 45 | 0.020 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.019 | Worm |
| negative regulation of synaptic vesicle exocytosis | GO:2000301 | 3 | 0.019 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.019 | Worm |
| protein localization to chromosome centromeric region | GO:0071459 | 1 | 0.019 | |
| digestive tract development | GO:0048565 | 190 | 0.019 | Fly |
| fat cell differentiation | GO:0045444 | 160 | 0.019 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.019 | |
| cellular response to lipid | GO:0071396 | 145 | 0.019 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.019 | |
| epidermal growth factor receptor signaling pathway | GO:0007173 | 28 | 0.019 | Worm |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.018 | Yeast Mouse Worm Fly |
| urogenital system development | GO:0001655 | 261 | 0.018 | Fly |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.018 | |
| negative regulation of actin filament depolymerization | GO:0030835 | 9 | 0.018 | |
| positive regulation of growth | GO:0045927 | 104 | 0.018 | |
| muscle cell development | GO:0055001 | 133 | 0.018 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.018 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.018 | Yeast Fly |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.018 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 2 | 0.018 | |
| positive regulation of actin filament polymerization | GO:0030838 | 26 | 0.018 | |
| regulation of muscle tissue development | GO:1901861 | 97 | 0.018 | |
| cell cell adhesion via plasma membrane adhesion molecules | GO:0098742 | 40 | 0.018 | |
| actin filament depolymerization | GO:0030042 | 15 | 0.018 | |
| positive regulation of nitric oxide synthase activity | GO:0051000 | 2 | 0.018 | |
| cellular response to insulin stimulus | GO:0032869 | 78 | 0.018 | |
| positive regulation of nucleotide biosynthetic process | GO:0030810 | 26 | 0.018 | Yeast |
| regulation of cell projection assembly | GO:0060491 | 38 | 0.018 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.018 | Fly |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.017 | |
| single organism nuclear import | GO:1902593 | 95 | 0.017 | Fly |
| negative regulation of synaptic vesicle transport | GO:1902804 | 3 | 0.017 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.017 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.017 | |
| positive regulation of cell growth | GO:0030307 | 33 | 0.017 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.017 | |
| odontogenesis | GO:0042476 | 78 | 0.017 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.017 | Yeast |
| germ cell development | GO:0007281 | 185 | 0.017 | Worm Fly |
| spindle localization | GO:0051653 | 22 | 0.017 | |
| rap protein signal transduction | GO:0032486 | 3 | 0.017 | |
| methylation | GO:0032259 | 134 | 0.017 | |
| positive regulation of neuron projection development | GO:0010976 | 79 | 0.016 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.016 | |
| stem cell differentiation | GO:0048863 | 268 | 0.016 | Fly |
| gastrulation | GO:0007369 | 116 | 0.016 | Fly |
| t cell activation | GO:0042110 | 289 | 0.016 | |
| regulation of chemotaxis | GO:0050920 | 53 | 0.016 | |
| positive regulation of lyase activity | GO:0051349 | 11 | 0.016 | Yeast |
| positive regulation of rap gtpase activity | GO:0032854 | 3 | 0.016 | Worm |
| dna methylation | GO:0006306 | 43 | 0.016 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.016 | Worm Fly |
| rho protein signal transduction | GO:0007266 | 32 | 0.016 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.016 | |
| angiogenesis | GO:0001525 | 201 | 0.016 | |
| spermatid development | GO:0007286 | 108 | 0.016 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 40 | 0.016 | |
| dendrite development | GO:0016358 | 115 | 0.016 | |
| axon cargo transport | GO:0008088 | 33 | 0.016 | |
| regulation of system process | GO:0044057 | 200 | 0.016 | |
| lung development | GO:0030324 | 164 | 0.016 | Mouse |
| cell adhesion | GO:0007155 | 329 | 0.016 | |
| ossification | GO:0001503 | 216 | 0.016 | |
| tissue migration | GO:0090130 | 68 | 0.016 | Fly |
| heart contraction | GO:0060047 | 93 | 0.016 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.016 | Mouse |
| negative regulation of secretion by cell | GO:1903531 | 54 | 0.015 | |
| ear development | GO:0043583 | 200 | 0.015 | |
| adult behavior | GO:0030534 | 135 | 0.015 | |
| stem cell development | GO:0048864 | 219 | 0.015 | |
| cation homeostasis | GO:0055080 | 212 | 0.015 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.015 | Worm |
| synapse organization | GO:0050808 | 125 | 0.015 | |
| response to peptide hormone | GO:0043434 | 127 | 0.015 | |
| glial cell differentiation | GO:0010001 | 131 | 0.015 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.015 | Fly |
| establishment of endothelial blood brain barrier | GO:0014045 | 3 | 0.015 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.015 | |
| cardiac muscle contraction | GO:0060048 | 32 | 0.015 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.015 | |
| locomotory behavior | GO:0007626 | 195 | 0.015 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.015 | |
| cyclic nucleotide metabolic process | GO:0009187 | 59 | 0.015 | Yeast |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.015 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.015 | |
| inflammatory response | GO:0006954 | 244 | 0.015 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.015 | Yeast Mouse Worm Fly |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 30 | 0.015 | |
| microtubule polymerization or depolymerization | GO:0031109 | 26 | 0.015 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.015 | Worm |
| regulation of lamellipodium assembly | GO:0010591 | 3 | 0.015 | |
| appendage morphogenesis | GO:0035107 | 149 | 0.014 | Fly |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.014 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.014 | Yeast Worm |
| b cell homeostasis | GO:0001782 | 34 | 0.014 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.014 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.014 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.014 | |
| oocyte differentiation | GO:0009994 | 35 | 0.014 | Fly |
| protein localization to membrane | GO:0072657 | 108 | 0.014 | |
| immune effector process | GO:0002252 | 321 | 0.014 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.014 | Mouse |
| sequestering of metal ion | GO:0051238 | 19 | 0.014 | |
| ventricular cardiac muscle tissue morphogenesis | GO:0055010 | 32 | 0.014 | |
| negative regulation of homeostatic process | GO:0032845 | 71 | 0.014 | |
| regulation of ossification | GO:0030278 | 112 | 0.014 | |
| cytokine production | GO:0001816 | 319 | 0.014 | |
| phenol containing compound metabolic process | GO:0018958 | 60 | 0.014 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.014 | Yeast |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.014 | Worm |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.014 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.014 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.014 | |
| positive regulation of synapse assembly | GO:0051965 | 18 | 0.014 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.014 | Mouse |
| regulation of extent of cell growth | GO:0061387 | 52 | 0.013 | |
| cell cell adhesion | GO:0098609 | 41 | 0.013 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.013 | |
| visual behavior | GO:0007632 | 45 | 0.013 | Mouse |
| rna splicing | GO:0008380 | 54 | 0.013 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.013 | |
| regulation of rac protein signal transduction | GO:0035020 | 19 | 0.013 | Mouse |
| calcium mediated signaling | GO:0019722 | 46 | 0.013 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.013 | |
| acrosome assembly | GO:0001675 | 11 | 0.013 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.013 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.013 | |
| activation of mapkkk activity | GO:0000185 | 1 | 0.013 | |
| muscle contraction | GO:0006936 | 101 | 0.013 | |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.013 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.013 | |
| cerebral cortex development | GO:0021987 | 86 | 0.013 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.013 | |
| positive regulation of cyclic nucleotide metabolic process | GO:0030801 | 24 | 0.013 | Yeast |
| microtubule based transport | GO:0010970 | 50 | 0.013 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.013 | Yeast Fly |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.013 | |
| t cell differentiation | GO:0030217 | 174 | 0.013 | |
| response to acid chemical | GO:0001101 | 111 | 0.013 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.013 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.013 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.013 | |
| learning or memory | GO:0007611 | 148 | 0.013 | Mouse |
| protein processing | GO:0016485 | 163 | 0.013 | |
| g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger | GO:0007187 | 55 | 0.013 | Yeast |
| second messenger mediated signaling | GO:0019932 | 73 | 0.013 | |
| fatty acid metabolic process | GO:0006631 | 121 | 0.013 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.013 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.013 | |
| sensory perception of chemical stimulus | GO:0007606 | 51 | 0.013 | |
| cell fate determination involved in pattern specification | GO:0060582 | 1 | 0.013 | |
| response to mineralocorticoid | GO:0051385 | 1 | 0.013 | |
| connective tissue development | GO:0061448 | 179 | 0.013 | |
| cell matrix adhesion | GO:0007160 | 68 | 0.012 | |
| cellular response to starvation | GO:0009267 | 57 | 0.012 | Fly |
| regulation of protein transport | GO:0051223 | 163 | 0.012 | |
| amide transport | GO:0042886 | 138 | 0.012 | |
| hair cycle | GO:0042633 | 90 | 0.012 | |
| response to radiation | GO:0009314 | 165 | 0.012 | Mouse |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.012 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.012 | |
| regulation of cell size | GO:0008361 | 72 | 0.012 | Fly |
| renal system development | GO:0072001 | 225 | 0.012 | Fly |
| protein maturation | GO:0051604 | 176 | 0.012 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 71 | 0.012 | |
| asymmetric neuroblast division | GO:0055059 | 1 | 0.012 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.012 | Fly |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.012 | |
| positive regulation of filopodium assembly | GO:0051491 | 10 | 0.012 | |
| macromolecule methylation | GO:0043414 | 120 | 0.012 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.012 | |
