Mus musculus

0 known processes

Tmem66

transmembrane protein 66

(Aliases: 1810045K07Rik)

Tmem66 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein catabolic processGO:00301632210.121
regulation of cellular amino acid metabolic processGO:000652150.111
cellular amino acid metabolic processGO:00065201030.099
modification dependent macromolecule catabolic processGO:00436321330.091
cellular ketone metabolic processGO:0042180840.084
proteolysis involved in cellular protein catabolic processGO:00516031470.083
cellular amine metabolic processGO:0044106440.083
amine metabolic processGO:0009308450.082
macromolecule catabolic processGO:00090572810.078
cellular protein catabolic processGO:00442571550.072
cellular macromolecule catabolic processGO:00442652060.065
protein modification by small protein conjugation or removalGO:00706472070.061
apoptotic signaling pathwayGO:00971903060.061
regulation of cellular amine metabolic processGO:0033238200.060
cation transportGO:00068123990.053
ubiquitin dependent protein catabolic processGO:00065111290.052
protein ubiquitinationGO:00165671710.051
modification dependent protein catabolic processGO:00199411330.050
autophagyGO:0006914450.050
positive regulation of cellular amino acid metabolic processGO:004576430.048
regulation of cellular ketone metabolic processGO:0010565660.047
protein modification by small protein conjugationGO:00324461870.046
positive regulation of cellular amine metabolic processGO:003324050.045
regulation of cellular catabolic processGO:00313292420.041
positive regulation of protein phosphorylationGO:00019342420.041
regulation of cellular response to stressGO:00801351590.038
metal ion homeostasisGO:00550651890.037
oxidation reduction processGO:00551143420.037
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.036
regulation of protein localizationGO:00328802310.036
cellular chemical homeostasisGO:00550822150.035
cytoplasmic transportGO:00164822340.035
peptidyl amino acid modificationGO:00181933360.035
negative regulation of protein metabolic processGO:00512482820.035
regulation of transferase activityGO:00513382630.035
mapk cascadeGO:00001652810.034
negative regulation of cellular protein metabolic processGO:00322692470.034
spermatogenesisGO:00072832840.034
positive regulation of protein modification processGO:00314012990.033
reactive oxygen species metabolic processGO:0072593840.033
negative regulation of cellular component organizationGO:00511291940.033
immune effector processGO:00022523210.033
negative regulation of intracellular signal transductionGO:19025321670.032
regulation of reactive oxygen species metabolic processGO:2000377400.031
cation transmembrane transportGO:00986552660.030
response to extracellular stimulusGO:00099911270.030
negative regulation of cellular amino acid metabolic processGO:004576300.030
positive regulation of programmed cell deathGO:00430682180.030
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.029
negative regulation of protein modification processGO:00314001630.029
response to oxidative stressGO:00069791230.029
regulation of intracellular transportGO:00323861590.029
protein localization to organelleGO:00333651850.028
regulation of mapk cascadeGO:00434082480.027
maintenance of locationGO:0051235890.027
intracellular protein transportGO:00068862040.026
nitrogen compound transportGO:00717052710.026
action potentialGO:0001508780.026
transmembrane transportGO:00550854120.026
positive regulation of apoptotic processGO:00430652170.026
cytokine productionGO:00018163190.026
cellular lipid metabolic processGO:00442553230.026
male gamete generationGO:00482322850.025
cellular homeostasisGO:00197252400.025
response to endoplasmic reticulum stressGO:0034976530.025
negative regulation of cell proliferationGO:00082852960.025
regulation of kinase activityGO:00435492490.025
organic hydroxy compound metabolic processGO:19016152030.024
regulation of phosphatidylcholine catabolic processGO:001089920.024
positive regulation of cell deathGO:00109422240.024
intrinsic apoptotic signaling pathwayGO:00971931320.024
cellular response to biotic stimulusGO:0071216920.024
defense response to other organismGO:00985421970.024
negative regulation of molecular functionGO:00440922580.023
alcohol metabolic processGO:00060661160.023
organonitrogen compound catabolic processGO:19015652640.023
small molecule catabolic processGO:0044282710.023
response to organic cyclic compoundGO:00140701980.023
regulation of secretionGO:00510462740.022
regulation of protein transportGO:00512231630.022
protein localization to nucleusGO:00345041210.022
regulation of cell cycleGO:00517262810.022
mitochondrion degradationGO:000042230.022
dna metabolic processGO:00062593030.022
regulation of protein catabolic processGO:00421761080.021
steroid metabolic processGO:00082021190.021
organic cyclic compound catabolic processGO:19013612950.021
inorganic ion transmembrane transportGO:00986602340.021
myeloid cell differentiationGO:00300992330.021
anion transportGO:00068201770.021
leukocyte differentiationGO:00025213420.021
nucleobase containing small molecule metabolic processGO:00550863520.020
cellular response to organonitrogen compoundGO:00714171450.020
membrane organizationGO:00610242450.020
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.020
fat cell differentiationGO:00454441600.020
lipoprotein metabolic processGO:0042157430.020
negative regulation of cellular amine metabolic processGO:003323910.020
endomembrane system organizationGO:00102561470.019
multicellular organismal signalingGO:0035637910.019
cation homeostasisGO:00550802120.019
regulation of vesicle mediated transportGO:00606271390.019
positive regulation of kinase activityGO:00336741550.019
cellular response to external stimulusGO:0071496880.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
regulation of organelle organizationGO:00330432890.019
extracellular structure organizationGO:00430621480.018
microtubule cytoskeleton organizationGO:00002261570.018
regulation of body fluid levelsGO:00508781620.018
localization within membraneGO:005166840.018
microtubule based processGO:00070172360.018
regulation of cytokine productionGO:00018172660.018
response to radiationGO:00093141650.018
anatomical structure homeostasisGO:00602491450.018
regulation of protein kinase activityGO:00458592320.018
cellular response to molecule of bacterial originGO:0071219830.018
regulation of apoptotic signaling pathwayGO:20012331970.017
negative regulation of phosphorus metabolic processGO:00105631840.017
organic hydroxy compound transportGO:0015850930.017
homeostasis of number of cellsGO:00488722100.017
small gtpase mediated signal transductionGO:0007264970.017
transmission of nerve impulseGO:0019226760.017
negative regulation of phosphate metabolic processGO:00459361840.017
cellular response to nutrient levelsGO:0031669640.017
positive regulation of transferase activityGO:00513471670.017
response to organonitrogen compoundGO:00102432460.017
divalent metal ion transportGO:00708381720.017
protein localization to vacuoleGO:007266540.017
ossificationGO:00015032160.017
heterocycle catabolic processGO:00467002800.017
i kappab kinase nf kappab signalingGO:0007249850.016
regulation of establishment of protein localizationGO:00702011810.016
ribose phosphate metabolic processGO:00196932910.016
myeloid leukocyte differentiationGO:00025731190.016
positive regulation of cellular catabolic processGO:00313311480.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
negative regulation of growthGO:0045926990.016
regulation of bindingGO:00510981110.016
regulation of protein modification by small protein conjugation or removalGO:1903320570.016
regulation of secretion by cellGO:19035302490.016
divalent inorganic cation transportGO:00725111780.016
t cell activationGO:00421102890.016
glycerolipid metabolic processGO:00464861220.016
response to peptideGO:19016521360.016
carbohydrate derivative catabolic processGO:19011362310.016
inclusion body assemblyGO:007084130.016
regulation of protein ubiquitinationGO:0031396520.016
muscle tissue developmentGO:00605373080.016
protein importGO:00170381010.016
peptidyl tyrosine phosphorylationGO:00181081430.016
organic anion transportGO:00157111370.016
interspecies interaction between organismsGO:0044419830.016
nucleocytoplasmic transportGO:00069131390.015
phospholipid metabolic processGO:0006644870.015
nuclear transportGO:00511691390.015
regulation of cell activationGO:00508652890.015
positive regulation of macrophage derived foam cell differentiationGO:001074440.015
cellular ion homeostasisGO:00068731650.015
organophosphate catabolic processGO:00464342320.015
striated muscle tissue developmentGO:00147062930.015
positive regulation of reactive oxygen species metabolic processGO:2000379110.015
sensory perceptionGO:00076002450.015
regulation of cell cycle processGO:00105641600.015
glycerophospholipid metabolic processGO:0006650710.015
germ cell developmentGO:00072811850.015
positive regulation of cholesterol storageGO:001088630.015
response to molecule of bacterial originGO:00022371430.015
regulation of hydrolase activityGO:00513362460.015
nucleotide metabolic processGO:00091173320.015
cellular response to extracellular stimulusGO:0031668810.015
regulation of multi organism processGO:00439001110.015
positive regulation of protein kinase activityGO:00458601440.015
ion transmembrane transportGO:00342203610.015
mitotic cell cycleGO:00002781950.015
protein acylationGO:0043543640.015
negative regulation of phosphorylationGO:00423261660.015
purine ribonucleotide metabolic processGO:00091502900.015
dna recombinationGO:0006310920.014
purine nucleoside metabolic processGO:00422782410.014
reactive nitrogen species metabolic processGO:200105700.014
lysosomal transportGO:0007041100.014
endocytosisGO:00068971680.014
cellular response to lipidGO:00713961450.014
protein lipidationGO:0006497280.014
substantia nigra developmentGO:002176220.014
negative regulation of defense responseGO:0031348770.014
protein import into nucleusGO:0006606950.014
retrograde transport endosome to golgiGO:004214720.014
cell adhesionGO:00071553290.014
organelle fissionGO:00482851700.014
cellular metal ion homeostasisGO:00068751510.014
regulation of cell motilityGO:20001452360.014
protein targeting to vacuoleGO:000662330.014
negative regulation of multi organism processGO:0043901680.014
protein refoldingGO:004202610.014
regionalizationGO:00030023370.014
single organism nuclear importGO:1902593950.014
lipid localizationGO:00108761260.014
peptidyl tyrosine modificationGO:00182121450.014
negative regulation of protein transportGO:0051224460.014
negative regulation of cell developmentGO:00107211690.014
posttranscriptional regulation of gene expressionGO:00106081550.014
cellular response to oxidative stressGO:0034599760.014
sequestering of calcium ionGO:0051208180.014
regulation of intracellular protein transportGO:0033157820.014
response to oxygen levelsGO:0070482620.014
nucleoside triphosphate metabolic processGO:00091412300.014
purine nucleotide metabolic processGO:00061633020.014
nucleoside phosphate metabolic processGO:00067533380.014
sterol transmembrane transportGO:003538220.014
positive regulation of secretion by cellGO:19035321140.014
calcium ion homeostasisGO:00550741270.014
response to starvationGO:0042594650.014
regulation of homeostatic processGO:00328441820.014
lipid biosynthetic processGO:00086101790.013
regulation of lymphocyte activationGO:00512492400.013
regulation of cytoplasmic transportGO:19036491120.013
positive regulation of mapk cascadeGO:00434101700.013
regulation of cellular component biogenesisGO:00440871810.013
negative regulation of nervous system developmentGO:00519611560.013
cellular response to growth factor stimulusGO:00713631970.013
growth of symbiont in hostGO:0044117230.013
zygotic determination of anterior posterior axis embryoGO:000735430.013
misfolded protein transportGO:007084310.013
nuclear divisionGO:00002801580.013
negative regulation of cell cycleGO:00457861230.013
response to nutrient levelsGO:00316671090.013
inorganic cation transmembrane transportGO:00986622070.013
aromatic compound catabolic processGO:00194392860.013
mitotic cell cycle processGO:19030471590.013
wnt signaling pathwayGO:00160551880.013
canonical wnt signaling pathwayGO:00600701300.013
g protein coupled receptor signaling pathwayGO:00071862430.013
meiotic cell cycleGO:00513211220.013
regulation of membrane potentialGO:00423911920.013
negative regulation of protein phosphorylationGO:00019331260.013
regulation of defense response to bacteriumGO:190042430.013
regulation of protein bindingGO:0043393600.013
cellular response to topologically incorrect proteinGO:0035967250.013
regulation of removal of superoxide radicalsGO:200012140.013
calcium ion transportGO:00068161590.013
phagocytosisGO:0006909660.013
lipoprotein biosynthetic processGO:0042158330.012
regulation of cell migrationGO:00303342190.012
neuronal action potentialGO:0019228540.012
ribonucleotide catabolic processGO:00092612080.012
sterol metabolic processGO:0016125580.012
negative regulation of cytokine productionGO:0001818840.012
regulation of inclusion body assemblyGO:009008310.012
positive regulation of cell developmentGO:00107202370.012
cellular nitrogen compound catabolic processGO:00442702800.012
ensheathment of neuronsGO:0007272760.012
er nucleus signaling pathwayGO:0006984270.012
locomotory behaviorGO:00076261950.012
gonad developmentGO:00084061410.012
protein maturationGO:00516041760.012
cholesterol transportGO:0030301380.012
lipid transportGO:0006869980.012
nuclear importGO:0051170950.012
plasma cell differentiationGO:000231730.012
multicellular organismal homeostasisGO:00488711640.012
establishment of protein localization to vacuoleGO:007266640.012
ras protein signal transductionGO:0007265770.012
actin cytoskeleton organizationGO:00300362200.012
dephosphorylationGO:00163111290.012
cellular protein complex assemblyGO:00436231160.012
nucleoside metabolic processGO:00091162460.012
regulation of map kinase activityGO:00434051200.012
lymphocyte proliferationGO:00466511640.012
positive regulation of organelle organizationGO:00106381280.012
positive regulation of lymphocyte activationGO:00512511400.012
lymphocyte differentiationGO:00300982420.012
regulation of cellular protein catabolic processGO:1903362610.012
single organismal cell cell adhesionGO:00163371310.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
sterol transportGO:0015918380.012
positive regulation of protein catabolic processGO:0045732600.012
cell growthGO:00160491300.011
response to light stimulusGO:00094161350.011
circulatory system processGO:00030131970.011
production of molecular mediator of immune responseGO:00024401030.011
exocytosisGO:00068871210.011
sequestering of metal ionGO:0051238190.011
leukocyte proliferationGO:00706611720.011
lipid catabolic processGO:0016042690.011
response to lipopolysaccharideGO:00324961280.011
ribonucleoside metabolic processGO:00091192450.011
purine containing compound metabolic processGO:00725213110.011
response to bacterial lipoproteinGO:003249340.011
regulation of proteolysisGO:00301621640.011
compound eye developmentGO:004874910.011
camera type eye developmentGO:00430102660.011
rho protein signal transductionGO:0007266320.011
single organism cell adhesionGO:00986021560.011
epithelial cell proliferationGO:00506731740.011
meiotic nuclear divisionGO:00071261150.011
gliogenesisGO:00420631410.011
regulation of lymphocyte proliferationGO:00506701170.011
organic acid biosynthetic processGO:0016053860.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
response to topologically incorrect proteinGO:0035966250.011
regulation of t cell activationGO:00508631700.011
l amino acid transportGO:0015807320.011
regulation of lipid metabolic processGO:00192161180.011
inflammatory responseGO:00069542440.011
response to growth factorGO:00708481980.011
histone modificationGO:00165701590.011
positive regulation of proteolysisGO:0045862850.011
carbohydrate derivative biosynthetic processGO:19011371830.011
small molecule biosynthetic processGO:00442831320.011
nucleoside catabolic processGO:00091642060.011
water soluble vitamin biosynthetic processGO:004236430.011
second messenger mediated signalingGO:0019932730.011
purine ribonucleotide catabolic processGO:00091542080.011
positive regulation of cell activationGO:00508671580.011
regulation of response to woundingGO:19030341890.011
skin developmentGO:00435882200.011
ribonucleotide metabolic processGO:00092592910.011
purine nucleoside catabolic processGO:00061522050.011
organonitrogen compound biosynthetic processGO:19015661920.011
epidermis developmentGO:00085441870.011
cell activation involved in immune responseGO:00022631260.011
progesterone metabolic processGO:004244840.010
purine ribonucleoside triphosphate metabolic processGO:00092052200.010
regulation of defense responseGO:00313472330.010
divalent inorganic cation homeostasisGO:00725071380.010
leukocyte migrationGO:00509001240.010
glial cell differentiationGO:00100011310.010
positive regulation of cytokine productionGO:00018191740.010
pharynx developmentGO:006046510.010
b cell activationGO:00421131610.010
positive regulation of macroautophagyGO:001623930.010
muscle contractionGO:00069361010.010
cellular response to starvationGO:0009267570.010
nucleoside phosphate catabolic processGO:19012922220.010
regulation of anatomical structure sizeGO:00900661780.010
purine ribonucleoside metabolic processGO:00461282410.010
cell type specific apoptotic processGO:00972852680.010

Tmem66 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.065
musculoskeletal system diseaseDOID:1700.065
disease of anatomical entityDOID:700.065
nervous system diseaseDOID:86300.041
bone diseaseDOID:008000100.027
disease of metabolismDOID:001466700.027
central nervous system diseaseDOID:33100.020
brain diseaseDOID:93600.020
immune system diseaseDOID:291400.015
acquired metabolic diseaseDOID:006015800.014
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.012
hematopoietic system diseaseDOID:7400.011
bone remodeling diseaseDOID:008000500.010
inherited metabolic disorderDOID:65500.010