Mus musculus

40 known processes

Lig1

ligase I, DNA, ATP-dependent

(Aliases: LigI,AL033288)

Lig1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.907
dna replicationGO:0006260520.813
meiosis iGO:0007127600.690
cellular response to dna damage stimulusGO:00069742070.660
dna recombinationGO:0006310920.655
dna dependent dna replicationGO:0006261240.641
regulation of mitotic cell cycle phase transitionGO:1901990730.619
recombinational repairGO:0000725210.549
mitotic cell cycleGO:00002781950.484
purine nucleoside catabolic processGO:00061522050.482
dna repairGO:00062811070.466
double strand break repair via homologous recombinationGO:0000724210.443
nuclear dna replicationGO:003326030.429
dna unwinding involved in dna replicationGO:000626850.427
chromatin organizationGO:00063252060.389
mitotic cell cycle processGO:19030471590.377
dna endoreduplicationGO:004202340.374
chromosome segregationGO:0007059480.309
organelle fissionGO:00482851700.304
translesion synthesisGO:001998510.293
nucleobase containing small molecule metabolic processGO:00550863520.277
dna dependent dna replication maintenance of fidelityGO:004500530.274
meiotic nuclear divisionGO:00071261150.266
double strand break repairGO:0006302480.257
cell cell signaling involved in cell fate commitmentGO:0045168350.242
regulation of cell cycle phase transitionGO:1901987770.230
lateral inhibitionGO:004633110.229
cellular nitrogen compound catabolic processGO:00442702800.226
meiotic cell cycleGO:00513211220.220
meiotic cell cycle processGO:1903046770.217
negative regulation of mitotic cell cycleGO:0045930580.216
regulation of transcription by chromatin organizationGO:003440100.213
regulation of cell cycleGO:00517262810.192
mitotic sister chromatid segregationGO:0000070140.186
gene silencingGO:0016458380.173
regulation of cellular catabolic processGO:00313292420.172
intra s dna damage checkpointGO:003157340.168
regulation of cell cycle processGO:00105641600.162
purine nucleoside triphosphate metabolic processGO:00091442260.151
nuclear divisionGO:00002801580.148
development of primary sexual characteristicsGO:00451371430.147
regulation of mitotic cell cycleGO:00073461260.144
mitotic sister chromatid cohesionGO:000706410.139
purine containing compound metabolic processGO:00725213110.132
purine ribonucleoside metabolic processGO:00461282410.126
organic cyclic compound catabolic processGO:19013612950.111
aromatic compound catabolic processGO:00194392860.108
methylationGO:00322591340.107
regulation of cell cycle g2 m phase transitionGO:1902749100.106
ribonucleotide metabolic processGO:00092592910.103
nucleoside phosphate metabolic processGO:00067533380.095
endocytosisGO:00068971680.095
Worm
negative regulation of gene expression epigeneticGO:0045814150.094
microtubule based processGO:00070172360.093
sister chromatid cohesionGO:0007062120.092
g1 s transition of mitotic cell cycleGO:0000082570.092
gonad developmentGO:00084061410.091
cellular amino acid metabolic processGO:00065201030.088
microtubule cytoskeleton organizationGO:00002261570.088
dna hypermethylationGO:004402630.087
meiotic chromosome condensationGO:001003230.084
purine ribonucleotide catabolic processGO:00091542080.084
nucleoside monophosphate metabolic processGO:0009123850.083
atp catabolic processGO:0006200550.082
protein dna complex subunit organizationGO:0071824280.082
mitotic cell cycle checkpointGO:0007093310.082
negative regulation of cellular protein metabolic processGO:00322692470.081
dna conformation changeGO:0071103370.079
nucleoside phosphate catabolic processGO:19012922220.077
purine containing compound catabolic processGO:00725232130.076
heterocycle catabolic processGO:00467002800.076
reciprocal meiotic recombinationGO:0007131160.076
chromatin modificationGO:00165681870.075
purine ribonucleoside triphosphate metabolic processGO:00092052200.073
dna integrity checkpointGO:0031570280.073
inner cell mass cell proliferationGO:0001833150.070
nucleoside metabolic processGO:00091162460.070
cell cycle g1 s phase transitionGO:0044843570.069
negative regulation of mitotic cell cycle phase transitionGO:1901991450.069
chromosome organization involved in meiosisGO:0070192390.068
purine ribonucleotide metabolic processGO:00091502900.068
regulation of chromosome organizationGO:0033044830.067
regulation of protein transportGO:00512231630.066
negative regulation of chromatin silencingGO:003193610.066
cell cycle checkpointGO:0000075470.066
ribonucleotide catabolic processGO:00092612080.065
nucleotide metabolic processGO:00091173320.065
sister chromatid segregationGO:0000819200.063
macromolecule catabolic processGO:00090572810.062
intrinsic apoptotic signaling pathwayGO:00971931320.060
ribonucleoside triphosphate catabolic processGO:00092031990.060
covalent chromatin modificationGO:00165691630.058
base excision repairGO:000628490.057
organonitrogen compound catabolic processGO:19015652640.057
purine nucleotide metabolic processGO:00061633020.057
glycosyl compound metabolic processGO:19016572460.055
protein maturationGO:00516041760.055
nucleoside catabolic processGO:00091642060.054
dna geometric changeGO:003239270.053
female gamete generationGO:0007292740.053
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.053
negative regulation of cell cycle phase transitionGO:1901988480.053
mitotic chromosome condensationGO:000707610.052
macromolecule methylationGO:00434141200.052
protein modification by small protein conjugation or removalGO:00706472070.051
regulation of hydrolase activityGO:00513362460.050
intracellular protein transportGO:00068862040.050
rna dependent dna replicationGO:000627830.050
purine ribonucleoside catabolic processGO:00461302050.049
negative regulation of cell cycleGO:00457861230.049
organophosphate catabolic processGO:00464342320.048
protein processingGO:00164851630.047
response to radiationGO:00093141650.047
regulation of dna dependent dna replication initiationGO:003017430.046
negative regulation of protein metabolic processGO:00512482820.045
spindle assembly involved in female meiosisGO:000705630.044
cellular amine metabolic processGO:0044106440.044
purine ribonucleoside triphosphate catabolic processGO:00092071990.043
protein methylationGO:0006479810.042
amine metabolic processGO:0009308450.042
protein ubiquitinationGO:00165671710.042
ribonucleoside metabolic processGO:00091192450.042
response to inorganic substanceGO:0010035960.042
nucleotide catabolic processGO:00091662170.041
cellular ketone metabolic processGO:0042180840.041
purine ribonucleoside monophosphate catabolic processGO:0009169570.041
regulation of cellular response to stressGO:00801351590.040
nucleoside triphosphate metabolic processGO:00091412300.040
cellular protein catabolic processGO:00442571550.039
membrane organizationGO:00610242450.039
histone methylationGO:0016571710.039
reciprocal dna recombinationGO:0035825160.038
oxidation reduction processGO:00551143420.038
heterochromatin organizationGO:007082840.037
double strand break repair via nonhomologous end joiningGO:0006303100.035
positive regulation of cellular amine metabolic processGO:003324050.034
germ cell developmentGO:00072811850.034
nucleoside monophosphate catabolic processGO:0009125590.034
regulation of cellular amino acid metabolic processGO:000652150.033
purine nucleoside monophosphate catabolic processGO:0009128580.033
dna damage checkpointGO:0000077260.033
ribose phosphate metabolic processGO:00196932910.033
protein heterotetramerizationGO:005129040.033
cell cycle g2 m phase transitionGO:0044839200.033
nitrogen compound transportGO:00717052710.033
anion homeostasisGO:0055081160.032
carbohydrate derivative catabolic processGO:19011362310.032
negative regulation of gene silencingGO:006096920.032
female meiotic divisionGO:0007143210.031
cell fate commitmentGO:00451652100.031
spermatogenesisGO:00072832840.031
organism emergence from protective structureGO:007168440.031
camera type eye developmentGO:00430102660.031
positive regulation of cellular amino acid metabolic processGO:004576430.030
regulation of secretion by cellGO:19035302490.030
regulation of secretionGO:00510462740.030
regulation of cellular amine metabolic processGO:0033238200.030
cellularizationGO:000734910.030
negative regulation of cell proliferationGO:00082852960.030
regulation of protein localizationGO:00328802310.030
deoxyribonucleotide biosynthetic processGO:000926360.030
negative regulation of atpase activityGO:003278020.029
negative regulation of protein phosphorylationGO:00019331260.029
receptor mediated endocytosisGO:0006898510.029
Worm
positive regulation of cellular catabolic processGO:00313311480.028
dna replication initiationGO:000627050.028
regulation of g2 m transition of mitotic cell cycleGO:0010389100.028
cell type specific apoptotic processGO:00972852680.028
negative regulation of nucleoside metabolic processGO:0045978110.028
ribonucleoside triphosphate metabolic processGO:00091992200.028
anatomical structure homeostasisGO:00602491450.028
positive regulation of cell cycleGO:0045787920.027
digestive system developmentGO:00551232000.027
response to organic cyclic compoundGO:00140701980.027
negative regulation of protein modification processGO:00314001630.027
mitotic nuclear divisionGO:0007067480.027
chromatin silencingGO:0006342150.027
response to organonitrogen compoundGO:00102432460.025
apoptotic signaling pathwayGO:00971903060.025
cytokinesisGO:0000910170.025
purine nucleoside triphosphate catabolic processGO:00091462030.025
microtubule cytoskeleton organization involved in mitosisGO:190285040.025
neuron apoptotic processGO:00514021420.025
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.025
regulation of neuron apoptotic processGO:00435231220.025
positive regulation of mitotic sister chromatid separationGO:190197020.024
nucleoside triphosphate catabolic processGO:00091432050.024
regulation of cytoplasmic transportGO:19036491120.024
cellular response to cytokine stimulusGO:00713451890.024
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.024
regulation of transferase activityGO:00513382630.023
positive regulation of organelle organizationGO:00106381280.023
regulation of organelle organizationGO:00330432890.023
dna duplex unwindingGO:003250870.023
ribonucleoside monophosphate metabolic processGO:0009161800.023
cellular homeostasisGO:00197252400.023
positive regulation of protein modification processGO:00314012990.022
regulation of kinase activityGO:00435492490.022
regulation of dna dependent dna replicationGO:009032980.022
purine nucleoside metabolic processGO:00422782410.022
positive regulation of protein kinase activityGO:00458601440.022
male gamete generationGO:00482322850.022
spindle midzone assemblyGO:005125510.022
asymmetric stem cell divisionGO:009872230.022
response to ionizing radiationGO:0010212420.022
fertilizationGO:00095661270.021
response to light stimulusGO:00094161350.021
positive regulation of cell deathGO:00109422240.021
regulation of cellular ketone metabolic processGO:0010565660.021
neuron deathGO:00709971540.021
organelle localizationGO:00516401790.021
ribonucleoside catabolic processGO:00424542060.021
cellular response to organonitrogen compoundGO:00714171450.021
nucleus organizationGO:0006997450.021
regulation of nucleotide metabolic processGO:00061401690.020
negative regulation of proteolysisGO:0045861740.020
chromosome separationGO:0051304140.020
small gtpase mediated signal transductionGO:0007264970.020
stem cell proliferationGO:00720891170.020
mitotic cytokinesisGO:000028140.020
hatchingGO:003518840.020
microtubule organizing center organizationGO:0031023280.020
signal transduction by p53 class mediatorGO:0072331510.020
protein localization to organelleGO:00333651850.020
cofactor metabolic processGO:0051186800.019
maintenance of locationGO:0051235890.019
positive regulation of apoptotic processGO:00430652170.019
regulation of response to dna damage stimulusGO:2001020340.019
glycosyl compound catabolic processGO:19016582060.019
negative regulation of protein processingGO:0010955790.019
positive regulation of histone modificationGO:0031058280.019
b cell activationGO:00421131610.018
dna methylationGO:0006306430.018
cell divisionGO:00513011200.018
atp metabolic processGO:0046034750.018
negative regulation of histone h3 k9 methylationGO:005157340.018
gland developmentGO:00487323300.018
dna biosynthetic processGO:0071897220.018
regulation of purine nucleotide metabolic processGO:19005421690.018
regulation of nucleotide catabolic processGO:00308111220.018
regulation of protein kinase activityGO:00458592320.018
digestive tract morphogenesisGO:00485461470.018
negative regulation of cell cycle processGO:0010948690.018
positive regulation of protein phosphorylationGO:00019342420.018
peptide transportGO:00158331330.018
type b pancreatic cell proliferationGO:0044342100.018
response to purine containing compoundGO:0014074280.018
s adenosylhomocysteine metabolic processGO:004649810.018
regulation of defense responseGO:00313472330.017
regulation of neuron deathGO:19012141340.017
oogenesisGO:0048477560.017
g2 m transition of mitotic cell cycleGO:0000086200.017
cellular macromolecule catabolic processGO:00442652060.017
regulation of protein maturationGO:1903317960.017
amide transportGO:00428861380.017
sensory organ morphogenesisGO:00905962420.017
inflammatory responseGO:00069542440.017
sulfur compound metabolic processGO:00067901000.017
regulation of cellular component biogenesisGO:00440871810.017
regulation of inflammatory responseGO:00507271470.016
regulation of intracellular transportGO:00323861590.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.016
alpha amino acid metabolic processGO:1901605590.016
exocrine pancreas developmentGO:003101770.016
peptidyl amino acid modificationGO:00181933360.016
histone lysine methylationGO:0034968500.016
negative regulation of phosphate metabolic processGO:00459361840.016
asymmetric neuroblast divisionGO:005505910.016
negative regulation of cell sizeGO:004579230.016
negative regulation of molecular functionGO:00440922580.016
leukocyte proliferationGO:00706611720.016
peptide secretionGO:00027901140.016
mitotic recombinationGO:000631230.016
coenzyme metabolic processGO:0006732520.015
somatic recombination of immunoglobulin gene segmentsGO:0016447420.015
regulation of intracellular protein transportGO:0033157820.015
response to extracellular stimulusGO:00099911270.015
anion transportGO:00068201770.015
organonitrogen compound biosynthetic processGO:19015661920.015
dna packagingGO:0006323300.015
proteasomal protein catabolic processGO:0010498980.015
cellular lipid metabolic processGO:00442553230.015
nucleotide excision repairGO:0006289130.015
cellular modified amino acid metabolic processGO:0006575630.015
male meiosisGO:0007140370.015
small molecule biosynthetic processGO:00442831320.015
t cell activationGO:00421102890.015
gtp metabolic processGO:00460391440.015
ectodermal digestive tract developmentGO:000743910.015
organophosphate biosynthetic processGO:00904071220.015
skeletal system developmentGO:00015013560.015
purine nucleoside monophosphate metabolic processGO:0009126810.015
chromosome condensationGO:0030261100.015
regulation of endopeptidase activityGO:0052548890.015
cation transportGO:00068123990.014
resolution of meiotic recombination intermediatesGO:000071240.014
release of cytochrome c from mitochondriaGO:0001836230.014
genitalia developmentGO:0048806370.014
regulation of proteolysisGO:00301621640.014
protein alkylationGO:0008213810.014
negative regulation of cell developmentGO:00107211690.014
connective tissue developmentGO:00614481790.014
purine ribonucleoside monophosphate metabolic processGO:0009167800.014
positive regulation of proteolysisGO:0045862850.014
blastocyst developmentGO:0001824800.014
blastocyst growthGO:0001832230.014
production of molecular mediator of immune responseGO:00024401030.014
regulation of histone modificationGO:0031056560.014
nucleocytoplasmic transportGO:00069131390.014
carbohydrate derivative biosynthetic processGO:19011371830.014
protein catabolic processGO:00301632210.014
response to oxidative stressGO:00069791230.014
regulation of purine nucleotide catabolic processGO:00331211220.014
positive regulation of programmed cell deathGO:00430682180.014
forebrain developmentGO:00309003020.014
regulation of lymphocyte activationGO:00512492400.014
regulation of apoptotic signaling pathwayGO:20012331970.014
negative regulation of chromosome organizationGO:2001251300.014
dna modificationGO:0006304500.014
endomembrane system organizationGO:00102561470.014
negative regulation of hydrolase activityGO:0051346710.013
rhythmic processGO:00485111740.013
deoxyribonucleotide metabolic processGO:0009262140.013
positive regulation of mitotic cell cycleGO:0045931410.013
regulation of chromatin modificationGO:1903308570.013
digestive tract developmentGO:00485651900.013
positive regulation of chromosome organizationGO:2001252330.013
mitotic sister chromatid separationGO:005130690.013
regulation of cysteine type endopeptidase activityGO:2000116650.013
regulation of dna replicationGO:0006275170.013
purine nucleotide catabolic processGO:00061952110.013
chromatin assembly or disassemblyGO:0006333160.013
negative regulation of intracellular signal transductionGO:19025321670.013
regulation of protein complex assemblyGO:0043254830.012
astral microtubule organizationGO:003095330.012
positive regulation of hydrolase activityGO:00513451480.012
protein targetingGO:00066051430.012
peptide hormone secretionGO:00300721090.012
synapsisGO:0007129340.012
non recombinational repairGO:0000726100.012
body morphogenesisGO:0010171450.012
regulation of cell motilityGO:20001452360.012
female sex differentiationGO:0046660840.012
cell maturationGO:00484691270.012
negative regulation of phosphorylationGO:00423261660.012
metaphase plate congressionGO:005131020.012
negative regulation of purine nucleotide metabolic processGO:1900543160.012
positive regulation of fibroblast proliferationGO:0048146200.012
rna catabolic processGO:0006401290.012
negative regulation of kinase activityGO:0033673810.012
developmental maturationGO:00217001930.012
regulation of atp metabolic processGO:1903578170.012
positive regulation of immune effector processGO:00026991070.012
circulatory system processGO:00030131970.012
engulfment of apoptotic cellGO:004365230.011
positive regulation of intracellular transportGO:0032388700.011
guanosine containing compound metabolic processGO:19010681440.011
regulation of multi organism processGO:00439001110.011
positive regulation of chromatin modificationGO:1903310280.011
regulation of interleukin 1 alpha productionGO:003265040.011
rna interferenceGO:001624620.011
ras protein signal transductionGO:0007265770.011
response to acid chemicalGO:00011011110.011
neural precursor cell proliferationGO:00613511210.011
regulation of chromosome segregationGO:0051983210.011
regulation of cell divisionGO:0051302760.011
negative regulation of nucleotide catabolic processGO:003081290.011
regulation of hormone levelsGO:00108172110.011
leukocyte differentiationGO:00025213420.011
protein import into nucleusGO:0006606950.011
lymphocyte proliferationGO:00466511640.011
regulation of cell migrationGO:00303342190.011
regulation of hormone secretionGO:0046883880.011
homeostasis of number of cellsGO:00488722100.011
positive regulation of cell cycle phase transitionGO:1901989170.011
positive regulation of cell activationGO:00508671580.011
rho protein signal transductionGO:0007266320.011
regulation of cell activationGO:00508652890.011
response to metal ionGO:0010038470.011
dna replication checkpointGO:000007620.011
learning or memoryGO:00076111480.011
cellular response to growth factor stimulusGO:00713631970.011
regulation of protein serine threonine kinase activityGO:00719001570.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
regulation of dna damage checkpointGO:200000130.011
glial cell differentiationGO:00100011310.011
striated muscle myosin thick filament assemblyGO:007168810.011
spindle organizationGO:0007051280.011
negative regulation of protein maturationGO:1903318790.010
cell activation involved in immune responseGO:00022631260.010
regulation of embryonic developmentGO:0045995710.010
positive regulation of histone methylationGO:0031062160.010
neural tube developmentGO:00219151600.010
cell junction organizationGO:0034330770.010
regulation of response to woundingGO:19030341890.010
response to oxygen levelsGO:0070482620.010
regulation of histone h3 k4 methylationGO:0051569120.010
response to temperature stimulusGO:0009266550.010
nuclear envelope organizationGO:0006998110.010
response to lipopolysaccharideGO:00324961280.010

Lig1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.422
disease of cellular proliferationDOID:1456600.422
organ system cancerDOID:005068600.183
gastrointestinal system cancerDOID:311900.164
large intestine cancerDOID:567200.067
intestinal cancerDOID:1015500.067
inherited metabolic disorderDOID:65500.054
disease of metabolismDOID:001466700.054
carbohydrate metabolic disorderDOID:297800.053
colorectal cancerDOID:925600.042
nervous system diseaseDOID:86300.035
disease of anatomical entityDOID:700.035
neuropathyDOID:87000.035
thoracic cancerDOID:509300.014
breast cancerDOID:161200.014