Mus musculus

56 known processes

Lig3

ligase III, DNA, ATP-dependent

(Aliases: D11Wsu78e,MGC78176)

Lig3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:00062811070.205
dna metabolic processGO:00062593030.192
cellular amino acid metabolic processGO:00065201030.096
cellular response to dna damage stimulusGO:00069742070.094
chromatin organizationGO:00063252060.092
cellular amine metabolic processGO:0044106440.084
positive regulation of cellular amino acid metabolic processGO:004576430.075
male gamete generationGO:00482322850.074
positive regulation of cellular amine metabolic processGO:003324050.074
regulation of cellular amino acid metabolic processGO:000652150.070
organonitrogen compound catabolic processGO:19015652640.068
nucleoside phosphate metabolic processGO:00067533380.066
cellular ketone metabolic processGO:0042180840.066
organelle assemblyGO:00709251770.065
nucleoside triphosphate catabolic processGO:00091432050.057
peptidyl amino acid modificationGO:00181933360.054
purine nucleotide catabolic processGO:00061952110.054
protein localization to organelleGO:00333651850.052
purine ribonucleotide metabolic processGO:00091502900.050
purine nucleoside triphosphate metabolic processGO:00091442260.050
mitotic cell cycle processGO:19030471590.050
apoptotic signaling pathwayGO:00971903060.050
spermatogenesisGO:00072832840.050
leukocyte differentiationGO:00025213420.050
regulation of cellular ketone metabolic processGO:0010565660.050
carbohydrate derivative catabolic processGO:19011362310.050
covalent chromatin modificationGO:00165691630.050
purine ribonucleoside triphosphate catabolic processGO:00092071990.049
ribonucleoside metabolic processGO:00091192450.048
regulation of cellular component biogenesisGO:00440871810.047
organelle fissionGO:00482851700.047
nucleotide catabolic processGO:00091662170.047
purine nucleoside triphosphate catabolic processGO:00091462030.046
purine containing compound catabolic processGO:00725232130.046
germ cell developmentGO:00072811850.045
amine metabolic processGO:0009308450.045
purine nucleoside catabolic processGO:00061522050.044
cellular nitrogen compound catabolic processGO:00442702800.043
cellular component assembly involved in morphogenesisGO:00109271390.042
macromolecule glycosylationGO:0043413550.041
ribonucleoside catabolic processGO:00424542060.040
purine ribonucleoside triphosphate metabolic processGO:00092052200.040
purine ribonucleoside catabolic processGO:00461302050.039
macromolecule methylationGO:00434141200.039
chromatin modificationGO:00165681870.038
regulation of cellular amine metabolic processGO:0033238200.038
heterocycle catabolic processGO:00467002800.038
methylationGO:00322591340.038
regionalizationGO:00030023370.038
ribonucleotide metabolic processGO:00092592910.037
neural tube developmentGO:00219151600.036
ribonucleoside triphosphate catabolic processGO:00092031990.036
aromatic compound catabolic processGO:00194392860.036
nucleoside catabolic processGO:00091642060.036
embryonic epithelial tube formationGO:00018381300.036
ribose phosphate metabolic processGO:00196932910.036
glycosyl compound metabolic processGO:19016572460.035
ribonucleoside triphosphate metabolic processGO:00091992200.035
nuclear divisionGO:00002801580.035
nucleoside phosphate catabolic processGO:19012922220.035
regulation of anatomical structure sizeGO:00900661780.034
response to radiationGO:00093141650.034
regulation of synaptic growth at neuromuscular junctionGO:000858240.034
negative regulation of cellular component organizationGO:00511291940.034
regulation of organelle organizationGO:00330432890.034
oocyte axis specificationGO:000730920.033
glycosyl compound catabolic processGO:19016582060.033
nucleobase containing small molecule metabolic processGO:00550863520.033
cell adhesionGO:00071553290.033
meiotic nuclear divisionGO:00071261150.032
ribonucleotide catabolic processGO:00092612080.032
maternal determination of anterior posterior axis embryoGO:000835820.031
organophosphate catabolic processGO:00464342320.031
nucleotide metabolic processGO:00091173320.030
double strand break repairGO:0006302480.030
purine nucleotide metabolic processGO:00061633020.030
ras protein signal transductionGO:0007265770.030
skeletal system developmentGO:00015013560.030
regulation of cell activationGO:00508652890.029
purine ribonucleotide catabolic processGO:00091542080.029
intracellular protein transportGO:00068862040.028
purine ribonucleoside metabolic processGO:00461282410.028
purine nucleoside metabolic processGO:00422782410.028
establishment or maintenance of cytoskeleton polarityGO:003095220.028
epithelial tube formationGO:00721751300.028
epidermis developmentGO:00085441870.028
skin developmentGO:00435882200.028
morphogenesis of embryonic epitheliumGO:00163311590.027
tube closureGO:0060606910.027
organelle localizationGO:00516401790.026
morphogenesis of a polarized epitheliumGO:0001738370.026
establishment or maintenance of cell polarityGO:0007163860.026
histone methylationGO:0016571710.025
protein glycosylationGO:0006486550.025
tube formationGO:00351481400.025
nucleoside metabolic processGO:00091162460.025
t cell activationGO:00421102890.025
rac protein signal transductionGO:0016601130.025
immune effector processGO:00022523210.025
regulation of hydrolase activityGO:00513362460.025
single organism nuclear importGO:1902593950.024
embryonic organ morphogenesisGO:00485622760.024
histone modificationGO:00165701590.024
epithelial tube morphogenesisGO:00605623030.024
oocyte anterior posterior axis specificationGO:000731420.024
nucleocytoplasmic transportGO:00069131390.024
neural tube formationGO:00018411080.024
negative regulation of protein metabolic processGO:00512482820.024
mitotic cell cycleGO:00002781950.023
lymphocyte differentiationGO:00300982420.023
rna processingGO:00063961050.023
protein localization to nucleusGO:00345041210.023
oocyte constructionGO:000730820.023
gtp metabolic processGO:00460391440.023
gonad developmentGO:00084061410.023
gtp catabolic processGO:00061841430.022
cytoplasmic transportGO:00164822340.022
regulation of cytoskeleton organizationGO:00514931220.022
microtubule based processGO:00070172360.022
muscle tissue developmentGO:00605373080.022
protein modification by small protein conjugationGO:00324461870.022
nuclear importGO:0051170950.022
spermatid differentiationGO:00485151150.022
gland developmentGO:00487323300.022
cilium morphogenesisGO:00602711020.022
glycosylationGO:0070085620.022
actin cytoskeleton organizationGO:00300362200.022
digestive system developmentGO:00551232000.022
epithelial cell developmentGO:00020641590.022
regulation of neuron projection developmentGO:00109751690.022
digestive tract developmentGO:00485651900.021
carbohydrate metabolic processGO:00059752300.021
glycoprotein biosynthetic processGO:0009101890.021
protein importGO:00170381010.021
protein targetingGO:00066051430.021
purine containing compound metabolic processGO:00725213110.021
single organism cell adhesionGO:00986021560.021
developmental maturationGO:00217001930.021
small gtpase mediated signal transductionGO:0007264970.021
positive regulation of catenin import into nucleusGO:003541320.021
protein dna complex subunit organizationGO:0071824280.021
microtubule cytoskeleton organizationGO:00002261570.021
nucleoside triphosphate metabolic processGO:00091412300.021
skeletal system morphogenesisGO:00487052030.020
multicellular organism growthGO:00352641610.020
blastocyst developmentGO:0001824800.020
primary neural tube formationGO:0014020950.020
meiotic cell cycleGO:00513211220.020
cilium assemblyGO:0042384810.019
development of primary sexual characteristicsGO:00451371430.019
regulation of actin filament based processGO:0032970990.019
rho protein signal transductionGO:0007266320.019
cellular response to cytokine stimulusGO:00713451890.019
wnt signaling pathwayGO:00160551880.019
fertilizationGO:00095661270.019
homeostasis of number of cellsGO:00488722100.019
extracellular structure organizationGO:00430621480.019
circadian regulation of gene expressionGO:0032922480.019
regulation of cell adhesionGO:00301551540.019
sensory organ morphogenesisGO:00905962420.019
septum primum developmentGO:000328440.019
regulation of chromatin silencingGO:003193520.019
transmission of nerve impulseGO:0019226760.019
microtubule cytoskeleton organization involved in mitosisGO:190285040.018
leukocyte activation involved in immune responseGO:00023661260.018
neuronal action potentialGO:0019228540.018
heart morphogenesisGO:00030071780.018
regulation of organ morphogenesisGO:20000271440.018
positive regulation of growthGO:00459271040.018
protein methylationGO:0006479810.018
regulation of defense responseGO:00313472330.018
stem cell developmentGO:00488642190.018
glycoprotein metabolic processGO:00091001160.018
cell fate commitmentGO:00451652100.018
posttranscriptional regulation of gene expressionGO:00106081550.018
cellularizationGO:000734910.018
protein maturationGO:00516041760.018
endocytosisGO:00068971680.018
extracellular matrix organizationGO:00301981470.018
endodermal cell fate specificationGO:000171440.018
neural tube closureGO:0001843900.018
lymphocyte activation involved in immune responseGO:0002285930.018
nuclear transportGO:00511691390.018
positive regulation of cellular component biogenesisGO:0044089940.017
spermatid developmentGO:00072861080.017
spindle assembly involved in mitosisGO:009030740.017
dna modificationGO:0006304500.017
lymphocyte mediated immunityGO:00024491390.017
rna splicingGO:0008380540.017
regulation of establishment of protein localizationGO:00702011810.017
dna recombinationGO:0006310920.017
guanosine containing compound metabolic processGO:19010681440.017
membrane organizationGO:00610242450.017
endomembrane system organizationGO:00102561470.017
regulation of actin cytoskeleton organizationGO:0032956840.017
carbohydrate derivative biosynthetic processGO:19011371830.017
respiratory tube developmentGO:00303231670.017
organic cyclic compound catabolic processGO:19013612950.017
regulation of protein localizationGO:00328802310.017
muscle cell differentiationGO:00426922610.017
regulation of apoptotic signaling pathwayGO:20012331970.017
cell maturationGO:00484691270.016
dna alkylationGO:0006305430.016
positive regulation of protein phosphorylationGO:00019342420.016
establishment of protein localization to organelleGO:00725941180.016
regulation of neuron differentiationGO:00456642810.016
gene silencingGO:0016458380.016
placenta developmentGO:00018901400.016
adaptive immune responseGO:00022501550.016
guanosine containing compound catabolic processGO:19010691440.016
stem cell differentiationGO:00488632680.016
cellular response to lipidGO:00713961450.016
myelinationGO:0042552740.016
cellular homeostasisGO:00197252400.016
axon ensheathmentGO:0008366760.016
regulation of protein processingGO:0070613960.016
action potentialGO:0001508780.016
regulation of protein complex assemblyGO:0043254830.015
positive regulation of protein modification processGO:00314012990.015
dna conformation changeGO:0071103370.015
protein ubiquitinationGO:00165671710.015
cell junction maintenanceGO:003433140.015
dna methylationGO:0006306430.015
respiratory system developmentGO:00605411900.015
negative regulation of cell fate specificationGO:000999640.015
female meiosis chromosome segregationGO:001632110.015
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.015
myeloid cell differentiationGO:00300992330.015
intracellular mrna localizationGO:000829840.015
positive regulation of nervous system developmentGO:00519622210.015
positive regulation of hydrolase activityGO:00513451480.015
ribonucleoprotein complex disassemblyGO:003298830.015
maintenance of locationGO:0051235890.015
regulation of cytokine productionGO:00018172660.015
protein alkylationGO:0008213810.015
axonogenesisGO:00074092740.015
engulfment of apoptotic cellGO:004365230.015
regulation of cell cycleGO:00517262810.015
alpha beta t cell activationGO:0046631910.015
somatic cell dna recombinationGO:0016444510.015
response to organonitrogen compoundGO:00102432460.015
cell activation involved in immune responseGO:00022631260.015
peptidyl tyrosine modificationGO:00182121450.015
regulation of mrna splicing via spliceosomeGO:0048024320.015
compound eye developmentGO:004874910.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
striated muscle tissue developmentGO:00147062930.015
wound healingGO:00420601570.015
organonitrogen compound biosynthetic processGO:19015661920.014
male sex differentiationGO:00466611090.014
blastocyst growthGO:0001832230.014
camera type eye developmentGO:00430102660.014
cardiac chamber morphogenesisGO:0003206930.014
regulation of cell projection organizationGO:00313442060.014
peptidyl tyrosine phosphorylationGO:00181081430.014
multicellular organismal signalingGO:0035637910.014
leukocyte mediated immunityGO:00024431740.014
synaptic transmissionGO:00072683290.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
satellite cell activation involved in skeletal muscle regenerationGO:001490130.014
embryonic placenta developmentGO:0001892980.014
macromolecule catabolic processGO:00090572810.014
chromosome segregationGO:0007059480.014
cellular response to hormone stimulusGO:00328701500.014
b cell activationGO:00421131610.014
t cell differentiationGO:00302171740.014
negative regulation of cell proliferationGO:00082852960.014
negative regulation of cellular amine metabolic processGO:003323910.014
protein processingGO:00164851630.013
regulation of ras gtpase activityGO:0032318880.013
negative regulation of cellular protein metabolic processGO:00322692470.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
regulation of cellular component sizeGO:00325351210.013
development of primary male sexual characteristicsGO:0046546880.013
negative regulation of organelle organizationGO:0010639900.013
inflammatory responseGO:00069542440.013
regulation of response to woundingGO:19030341890.013
regulation of membrane potentialGO:00423911920.013
nucleotide excision repairGO:0006289130.013
cell junction organizationGO:0034330770.013
t cell proliferationGO:00420981200.013
regulation of hormone levelsGO:00108172110.013
regulation of nucleotide metabolic processGO:00061401690.013
histone lysine methylationGO:0034968500.013
cardiac chamber developmentGO:00032051080.013
pole plasm assemblyGO:000731520.013
negative regulation of cell developmentGO:00107211690.013
negative regulation of molecular functionGO:00440922580.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.013
leukocyte proliferationGO:00706611720.013
gastrulationGO:00073691160.013
positive regulation of cell developmentGO:00107202370.013
regulation of wnt signaling pathwayGO:00301111230.013
signal transduction by p53 class mediatorGO:0072331510.013
canonical wnt signaling pathwayGO:00600701300.013
response to molecule of bacterial originGO:00022371430.013
cell growthGO:00160491300.012
male anatomical structure morphogenesisGO:009059840.012
response to acid chemicalGO:00011011110.012
blood vessel morphogenesisGO:00485142850.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
protein import into nucleusGO:0006606950.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
ensheathment of neuronsGO:0007272760.012
regulation of protein maturationGO:1903317960.012
negative regulation of immune system processGO:00026832090.012
limb developmentGO:00601731660.012
embryonic skeletal system morphogenesisGO:0048704910.012
meiosis iGO:0007127600.012
regulation of hippo signalingGO:003533010.012
protein catabolic processGO:00301632210.012
cellular protein complex assemblyGO:00436231160.012
transmembrane transportGO:00550854120.012
peptidyl lysine modificationGO:0018205770.012
dephosphorylationGO:00163111290.012
negative regulation of posttranscriptional gene silencingGO:006014910.012
embryonic skeletal system developmentGO:00487061200.012
regulation of rho protein signal transductionGO:0035023710.012
regulation of leukocyte differentiationGO:19021051590.012
regulation of purine nucleotide catabolic processGO:00331211220.012
appendage morphogenesisGO:00351071490.012
regulation of nucleocytoplasmic transportGO:0046822730.012
chemotaxisGO:00069352470.012
establishment of planar polarityGO:0001736280.012
positive regulation of cell activationGO:00508671580.012
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.012
developmental growth involved in morphogenesisGO:00605601380.012
cellular protein catabolic processGO:00442571550.012
regulation of cell sizeGO:0008361720.012
synapse organizationGO:00508081250.012
activation of nf kappab inducing kinase activityGO:000725040.011
positive regulation of neuron differentiationGO:00456661410.011
establishment of organelle localizationGO:00516561220.011
positive regulation of transferase activityGO:00513471670.011
negative regulation of dna replicationGO:000815640.011
regulation of t cell activationGO:00508631700.011
male gonad developmentGO:0008584880.011
spinal cord developmentGO:0021510810.011
intracellular receptor signaling pathwayGO:0030522740.011
ear morphogenesisGO:00424711180.011
anatomical structure homeostasisGO:00602491450.011
mitotic cytokinesisGO:000028140.011
modification dependent protein catabolic processGO:00199411330.011
cellular response to peptide hormone stimulusGO:0071375920.011
reactive oxygen species metabolic processGO:0072593840.011
mrna processingGO:0006397630.011
oxidation reduction processGO:00551143420.011
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
reactive oxygen species biosynthetic processGO:190340980.011
translationGO:0006412930.011
cellular response to organonitrogen compoundGO:00714171450.011
cell cycle switching mitotic to meiotic cell cycleGO:005172810.011
regulation of cellular response to stressGO:00801351590.011
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.011
immunoglobulin mediated immune responseGO:0016064690.011
regulation of satellite cell activation involved in skeletal muscle regenerationGO:001471730.011
single organismal cell cell adhesionGO:00163371310.011
cytokine mediated signaling pathwayGO:00192211150.011
cation homeostasisGO:00550802120.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
cell substrate adhesionGO:00315891300.011
regulation of lymphocyte mediated immunityGO:0002706840.011
cellular response to peptideGO:1901653920.011
cellular carbohydrate metabolic processGO:00442621190.011
regulation of ras protein signal transductionGO:00465781140.011
positive regulation of wnt signaling pathwayGO:0030177450.011
nitrogen compound transportGO:00717052710.011
cell cell junction organizationGO:0045216720.011
regulation of nucleotide catabolic processGO:00308111220.011
regulation of vesicle mediated transportGO:00606271390.011
g1 s transition of mitotic cell cycleGO:0000082570.011
fat cell differentiationGO:00454441600.010
male meiosisGO:0007140370.010
positive regulation of apoptotic processGO:00430652170.010
actin filament organizationGO:00070151130.010
macromolecular complex disassemblyGO:0032984430.010
negative regulation of mitotic cell cycleGO:0045930580.010
regulation of cytoplasmic transportGO:19036491120.010
regulation of peptidyl tyrosine phosphorylationGO:0050730930.010
regulation of purine nucleotide metabolic processGO:19005421690.010
ion transmembrane transportGO:00342203610.010
lung developmentGO:00303241640.010
response to light stimulusGO:00094161350.010
meiotic cell cycle processGO:1903046770.010
positive regulation of cell cycleGO:0045787920.010
appendage developmentGO:00487361660.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
rhythmic processGO:00485111740.010
columnar cuboidal epithelial cell differentiationGO:0002065820.010
protein modification by small protein conjugation or removalGO:00706472070.010
cell type specific apoptotic processGO:00972852680.010
nucleoside monophosphate metabolic processGO:0009123850.010
production of molecular mediator of immune responseGO:00024401030.010
regulation of inflammatory responseGO:00507271470.010
positive regulation of cell deathGO:00109422240.010
ossificationGO:00015032160.010
positive regulation of purine nucleotide catabolic processGO:0033123880.010
nucleus organizationGO:0006997450.010
cation transportGO:00068123990.010
digestive tract morphogenesisGO:00485461470.010
regulation of intracellular protein transportGO:0033157820.010
mapk cascadeGO:00001652810.010
response to growth factorGO:00708481980.010

Lig3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.026
disease of cellular proliferationDOID:1456600.026
organ system cancerDOID:005068600.026
nervous system diseaseDOID:86300.023
disease of anatomical entityDOID:700.023
immune system diseaseDOID:291400.021
musculoskeletal system diseaseDOID:1700.018
muscle tissue diseaseDOID:6600.017
muscular diseaseDOID:008000000.017
hematopoietic system diseaseDOID:7400.016
central nervous system diseaseDOID:33100.014
inherited metabolic disorderDOID:65500.014
disease of metabolismDOID:001466700.014
anemiaDOID:235500.014
eye diseaseDOID:561400.013
retinal degenerationDOID:846600.013
sensory system diseaseDOID:005015500.013
retinal diseaseDOID:567900.013
eye and adnexa diseaseDOID:149200.013
immune system cancerDOID:006008300.012
hematologic cancerDOID:253100.012