Mus musculus

0 known processes

Hmbs

hydroxymethylbilane synthase

(Aliases: T25658,PBGD,Ups,Uros1)

Hmbs biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
porphyrin containing compound metabolic processGO:0006778220.736
organonitrogen compound biosynthetic processGO:19015661920.536
iron sulfur cluster assemblyGO:001622630.454
mitochondrion organizationGO:00070051340.440
cofactor metabolic processGO:0051186800.331
cofactor biosynthetic processGO:0051188410.308
mitochondrial transportGO:0006839360.251
meiotic cell cycle processGO:1903046770.153
porphyrin containing compound biosynthetic processGO:0006779160.131
pigment biosynthetic processGO:0046148260.129
tetrapyrrole biosynthetic processGO:0033014160.125
meiosis iGO:0007127600.117
nucleobase containing small molecule metabolic processGO:00550863520.104
carbohydrate derivative biosynthetic processGO:19011371830.103
regulation of lipid metabolic processGO:00192161180.096
spermatogenesisGO:00072832840.094
nucleoside phosphate metabolic processGO:00067533380.092
nucleoside phosphate biosynthetic processGO:1901293790.092
purine containing compound metabolic processGO:00725213110.090
response to oxidative stressGO:00069791230.082
nucleotide metabolic processGO:00091173320.079
nucleoside monophosphate metabolic processGO:0009123850.076
cellular homeostasisGO:00197252400.076
nucleoside triphosphate metabolic processGO:00091412300.071
heme biosynthetic processGO:0006783120.069
ribonucleoside metabolic processGO:00091192450.067
ribose phosphate metabolic processGO:00196932910.067
purine ribonucleotide metabolic processGO:00091502900.066
cellular chemical homeostasisGO:00550822150.064
purine ribonucleoside triphosphate metabolic processGO:00092052200.063
gland developmentGO:00487323300.057
dna dependent dna replicationGO:0006261240.056
purine ribonucleoside metabolic processGO:00461282410.055
pigment metabolic processGO:0042440320.055
apoptotic signaling pathwayGO:00971903060.054
homeostasis of number of cellsGO:00488722100.054
membrane organizationGO:00610242450.053
regulation of apoptotic signaling pathwayGO:20012331970.049
purine nucleoside metabolic processGO:00422782410.049
regulation of mitochondrion organizationGO:0010821270.048
cellular lipid metabolic processGO:00442553230.048
dna metabolic processGO:00062593030.048
positive regulation of mitochondrion organizationGO:0010822170.048
nucleoside metabolic processGO:00091162460.048
purine nucleotide metabolic processGO:00061633020.048
t cell activationGO:00421102890.047
macromolecule catabolic processGO:00090572810.047
nucleotide biosynthetic processGO:0009165780.047
cellular metal ion homeostasisGO:00068751510.046
organelle fissionGO:00482851700.045
metallo sulfur cluster assemblyGO:003116330.045
spindle assembly involved in female meiosis iGO:000705720.044
ribonucleotide metabolic processGO:00092592910.043
organophosphate biosynthetic processGO:00904071220.041
meiotic cell cycleGO:00513211220.041
purine nucleoside triphosphate metabolic processGO:00091442260.040
response to superoxideGO:0000303160.039
cytoplasmic transportGO:00164822340.039
regulation of feeding behaviorGO:006025930.039
dna replicationGO:0006260520.039
regulation of lymphocyte activationGO:00512492400.039
organic cyclic compound catabolic processGO:19013612950.038
heme metabolic processGO:0042168160.036
male gamete generationGO:00482322850.036
ion transmembrane transportGO:00342203610.035
protein processingGO:00164851630.035
ribonucleoside monophosphate metabolic processGO:0009161800.034
cellular macromolecule catabolic processGO:00442652060.034
mitochondrial fusionGO:000805390.034
tetrapyrrole metabolic processGO:0033013220.033
cellular ion homeostasisGO:00068731650.033
heterocycle catabolic processGO:00467002800.033
cellular response to dna damage stimulusGO:00069742070.032
cation transportGO:00068123990.032
protein targetingGO:00066051430.032
ribonucleoside triphosphate metabolic processGO:00091992200.032
meiotic nuclear divisionGO:00071261150.031
apoptotic mitochondrial changesGO:0008637480.030
immune effector processGO:00022523210.030
erythrocyte differentiationGO:0030218880.030
purine ribonucleotide biosynthetic processGO:0009152590.030
cation transmembrane transportGO:00986552660.029
aromatic compound catabolic processGO:00194392860.029
transmembrane transportGO:00550854120.029
cellular ketone metabolic processGO:0042180840.028
positive regulation of apoptotic processGO:00430652170.028
carbohydrate metabolic processGO:00059752300.028
metal ion homeostasisGO:00550651890.027
glycerolipid metabolic processGO:00464861220.027
mitotic cell cycleGO:00002781950.027
mitotic cell cycle processGO:19030471590.026
sensory perceptionGO:00076002450.026
nuclear divisionGO:00002801580.025
response to growth factorGO:00708481980.025
cell growthGO:00160491300.025
extrinsic apoptotic signaling pathwayGO:00971911260.025
response to iron ionGO:001003940.025
protein catabolic processGO:00301632210.025
sulfur compound metabolic processGO:00067901000.024
purine ribonucleoside catabolic processGO:00461302050.024
regulation of organelle organizationGO:00330432890.024
cellular nitrogen compound catabolic processGO:00442702800.024
leukocyte differentiationGO:00025213420.024
cellular calcium ion homeostasisGO:00068741190.023
amine metabolic processGO:0009308450.023
extracellular structure organizationGO:00430621480.023
protein maturationGO:00516041760.023
myeloid cell differentiationGO:00300992330.023
germ cell developmentGO:00072811850.023
mitochondrial genome maintenanceGO:0000002150.022
regulation of cell activationGO:00508652890.022
cell type specific apoptotic processGO:00972852680.022
nitrogen compound transportGO:00717052710.022
cellular amine metabolic processGO:0044106440.022
phospholipid metabolic processGO:0006644870.021
regulation of hydrolase activityGO:00513362460.021
gtp metabolic processGO:00460391440.021
signal transduction in absence of ligandGO:0038034550.020
gonad developmentGO:00084061410.020
organonitrogen compound catabolic processGO:19015652640.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
negative regulation of apoptotic signaling pathwayGO:20012341040.020
response to reactive oxygen speciesGO:0000302560.020
t cell differentiationGO:00302171740.019
response to topologically incorrect proteinGO:0035966250.019
inorganic ion transmembrane transportGO:00986602340.019
purine nucleoside monophosphate metabolic processGO:0009126810.019
divalent inorganic cation transportGO:00725111780.019
calcium ion homeostasisGO:00550741270.019
atp metabolic processGO:0046034750.019
guanosine containing compound metabolic processGO:19010681440.019
nucleoside catabolic processGO:00091642060.019
cation homeostasisGO:00550802120.019
cytokine productionGO:00018163190.019
oxidation reduction processGO:00551143420.018
positive regulation of protein phosphorylationGO:00019342420.018
glycosyl compound metabolic processGO:19016572460.018
intracellular protein transportGO:00068862040.018
positive regulation of protein modification processGO:00314012990.018
leukocyte mediated immunityGO:00024431740.018
negative regulation of organelle organizationGO:0010639900.018
organelle assemblyGO:00709251770.018
development of primary sexual characteristicsGO:00451371430.018
inflammatory responseGO:00069542440.018
peptidyl amino acid modificationGO:00181933360.018
microtubule based processGO:00070172360.017
lymphocyte mediated immunityGO:00024491390.017
endocytosisGO:00068971680.017
dna recombinationGO:0006310920.017
lymphocyte differentiationGO:00300982420.017
regulation of membrane potentialGO:00423911920.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
anatomical structure homeostasisGO:00602491450.017
positive regulation of transferase activityGO:00513471670.017
purine nucleotide biosynthetic processGO:0006164650.017
microtubule cytoskeleton organizationGO:00002261570.017
regulation of cell cycleGO:00517262810.017
response to inorganic substanceGO:0010035960.017
mitochondrial membrane organizationGO:0007006260.017
response to unfolded proteinGO:0006986210.016
cellular amino acid metabolic processGO:00065201030.016
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.016
negative regulation of molecular functionGO:00440922580.016
transition metal ion homeostasisGO:0055076540.016
inorganic cation transmembrane transportGO:00986622070.016
regulation of cellular ketone metabolic processGO:0010565660.016
multicellular organism growthGO:00352641610.016
positive regulation of growthGO:00459271040.016
small gtpase mediated signal transductionGO:0007264970.016
negative regulation of immune system processGO:00026832090.015
negative regulation of intracellular signal transductionGO:19025321670.015
calcium ion transportGO:00068161590.015
extracellular matrix organizationGO:00301981470.015
divalent inorganic cation homeostasisGO:00725071380.015
purine nucleoside catabolic processGO:00061522050.015
divalent metal ion transportGO:00708381720.015
regulation of lymphocyte differentiationGO:00456191070.015
nucleocytoplasmic transportGO:00069131390.015
protein modification by small protein conjugation or removalGO:00706472070.015
regulation of cellular amine metabolic processGO:0033238200.015
alcohol metabolic processGO:00060661160.015
amide transportGO:00428861380.015
positive regulation of programmed cell deathGO:00430682180.015
activation of immune responseGO:00022531380.015
immune response activating cell surface receptor signaling pathwayGO:0002429720.015
feeding behaviorGO:0007631620.015
cellular response to oxidative stressGO:0034599760.014
establishment of protein localization to organelleGO:00725941180.014
response to oxygen radicalGO:0000305160.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
regulation of nucleoside metabolic processGO:00091181300.014
locomotory behaviorGO:00076261950.014
renal system developmentGO:00720012250.014
negative regulation of cell proliferationGO:00082852960.014
cellular transition metal ion homeostasisGO:0046916320.014
cd4 positive alpha beta t cell activationGO:0035710450.014
positive regulation of lipid metabolic processGO:0045834400.014
organ growthGO:00352651170.014
immune response activating signal transductionGO:00027571160.014
ribose phosphate biosynthetic processGO:0046390590.014
multi multicellular organism processGO:00447061090.014
liver developmentGO:0001889660.014
gtp catabolic processGO:00061841430.014
ribonucleotide catabolic processGO:00092612080.014
membrane fusionGO:0061025380.014
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.014
regulation of cellular response to stressGO:00801351590.014
purine containing compound biosynthetic processGO:0072522700.013
positive regulation of cell growthGO:0030307330.013
defecationGO:003042110.013
negative regulation of cellular component organizationGO:00511291940.013
regulation of mitochondrial membrane permeabilityGO:0046902170.013
positive regulation of cell deathGO:00109422240.013
response to oxygen levelsGO:0070482620.013
cellular protein complex assemblyGO:00436231160.013
positive regulation of hydrolase activityGO:00513451480.013
cellular response to growth factor stimulusGO:00713631970.013
protein ubiquitinationGO:00165671710.013
cellular response to cytokine stimulusGO:00713451890.013
modification dependent macromolecule catabolic processGO:00436321330.013
nucleoside monophosphate biosynthetic processGO:0009124120.012
regulation of purine nucleotide metabolic processGO:19005421690.012
skeletal system developmentGO:00015013560.012
regulation of glycogen catabolic processGO:000598120.012
neuromuscular processGO:0050905990.012
purine nucleoside biosynthetic processGO:0042451190.012
iron ion homeostasisGO:0055072360.012
cellular response to topologically incorrect proteinGO:0035967250.012
regulation of cellular component biogenesisGO:00440871810.012
immune response regulating signaling pathwayGO:00027641250.012
t cell receptor signaling pathwayGO:0050852460.012
negative regulation of cellular amine metabolic processGO:003323910.012
glycerophospholipid metabolic processGO:0006650710.012
positive regulation of cellular amine metabolic processGO:003324050.012
t cell proliferationGO:00420981200.012
purine nucleotide catabolic processGO:00061952110.012
epithelial cell proliferationGO:00506731740.012
mrna metabolic processGO:0016071840.012
organelle fusionGO:0048284280.012
guanosine containing compound catabolic processGO:19010691440.012
regulation of t cell activationGO:00508631700.011
rna processingGO:00063961050.011
single organism nuclear importGO:1902593950.011
ras protein signal transductionGO:0007265770.011
regulation of ion transportGO:00432692150.011
regulation of intracellular transportGO:00323861590.011
lung developmentGO:00303241640.011
regulation of cellular amino acid metabolic processGO:000652150.011
regulation of homeostatic processGO:00328441820.011
regulation of inflammatory responseGO:00507271470.011
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.011
mitochondrial protein processingGO:003498250.011
ribonucleotide biosynthetic processGO:0009260590.011
purine containing compound catabolic processGO:00725232130.011
regulation of cell growthGO:0001558910.011
morphogenesis of a branching epitheliumGO:00611381930.011
anion transportGO:00068201770.011
carbohydrate homeostasisGO:00335001280.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
response to molecule of bacterial originGO:00022371430.011
regulation of mapk cascadeGO:00434082480.011
cellular protein catabolic processGO:00442571550.011
regulation of neuron differentiationGO:00456642810.011
regulation of defense responseGO:00313472330.011
lymphocyte proliferationGO:00466511640.011
blood circulationGO:00080151950.011
wnt signaling pathwayGO:00160551880.011
nucleoside triphosphate catabolic processGO:00091432050.011
microtubule nucleationGO:000702020.011
positive regulation of mapk cascadeGO:00434101700.011
regulation of mitotic cell cycleGO:00073461260.011
myeloid cell homeostasisGO:00022621140.011
purine deoxyribonucleoside triphosphate metabolic processGO:000921570.011
regulation of establishment of protein localizationGO:00702011810.011
mitotic nuclear divisionGO:0007067480.011
response to lipopolysaccharideGO:00324961280.010
positive regulation of protein kinase activityGO:00458601440.010
alpha beta t cell activationGO:0046631910.010
dephosphorylationGO:00163111290.010
regulation of leukocyte differentiationGO:19021051590.010
deoxyribonucleotide metabolic processGO:0009262140.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
epithelial tube morphogenesisGO:00605623030.010
deoxyribose phosphate metabolic processGO:001969290.010
cellular carbohydrate metabolic processGO:00442621190.010
adult behaviorGO:00305341350.010
camera type eye developmentGO:00430102660.010
regulation of dna dependent dna replicationGO:009032980.010
mitochondrial dna replicationGO:000626470.010
wound healingGO:00420601570.010
muscle cell differentiationGO:00426922610.010
positive regulation of metalloenzyme activityGO:004855430.010
circulatory system processGO:00030131970.010
respiratory tube developmentGO:00303231670.010

Hmbs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
central nervous system diseaseDOID:33100.016
inherited metabolic disorderDOID:65500.015
Human
disease of metabolismDOID:001466700.015
Human