IMP: Integrative Multi-species Prediction

Mus musculus

171 known processes

Gdf7

growth differentiation factor 7

(Aliases: BMP12)

Entrez: 238057
Ensembl: ENSMUSG00000037660
UniProtKB: P43029

Process Predictions
Disease Predictions

Gdf7 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular amino acid metabolic process	GO:0006520	103	0.199
axial mesodermal cell fate commitment	GO:0048322	1	0.132	Mouse
roof plate formation	GO:0021509	1	0.128
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry	GO:1900164	2	0.125	Mouse
amine metabolic process	GO:0009308	45	0.124
regulation of cellular amine metabolic process	GO:0033238	20	0.122
regulation of cellular amino acid metabolic process	GO:0006521	5	0.120
cellular ketone metabolic process	GO:0042180	84	0.117
cellular amine metabolic process	GO:0044106	44	0.114
regulation of cellular ketone metabolic process	GO:0010565	66	0.104
multicellular organismal homeostasis	GO:0048871	164	0.102	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.095
cellular homeostasis	GO:0019725	240	0.094	Mouse
regulation of transferase activity	GO:0051338	263	0.092
cellular chemical homeostasis	GO:0055082	215	0.090	Mouse
synaptic transmission	GO:0007268	329	0.089
renal system development	GO:0072001	225	0.087	Mouse
nephrogenic mesenchyme development	GO:0072076	3	0.087	Mouse
regulation of cell cycle	GO:0051726	281	0.082	Worm
metal ion homeostasis	GO:0055065	189	0.075	Mouse
heterocycle catabolic process	GO:0046700	280	0.075
negative regulation of transferase activity	GO:0051348	85	0.072
trophectodermal cellular morphogenesis	GO:0001831	3	0.070	Mouse
spermatogenesis	GO:0007283	284	0.069	Mouse
purine containing compound metabolic process	GO:0072521	311	0.069
tendon cell differentiation	GO:0035990	4	0.068
cation homeostasis	GO:0055080	212	0.064	Mouse
regulation of kinase activity	GO:0043549	249	0.063
male gamete generation	GO:0048232	285	0.061	Mouse
mapk cascade	GO:0000165	281	0.061	Mouse
cellular ion homeostasis	GO:0006873	165	0.059	Mouse
response to organonitrogen compound	GO:0010243	246	0.057
nucleoside phosphate metabolic process	GO:0006753	338	0.056
regulation of protein serine threonine kinase activity	GO:0071900	157	0.055
muscle tissue development	GO:0060537	308	0.054	Mouse
connective tissue development	GO:0061448	179	0.053
sensory organ morphogenesis	GO:0090596	242	0.051	Mouse
purine ribonucleoside metabolic process	GO:0046128	241	0.051
carbohydrate metabolic process	GO:0005975	230	0.051
organelle fission	GO:0048285	170	0.050
regulation of cell projection organization	GO:0031344	206	0.050
ribose phosphate metabolic process	GO:0019693	291	0.049
embryonic placenta development	GO:0001892	98	0.049	Mouse
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.049
muscle cell differentiation	GO:0042692	261	0.049	Mouse
transmembrane transport	GO:0055085	412	0.046
organic cyclic compound catabolic process	GO:1901361	295	0.046
positive regulation of cellular amine metabolic process	GO:0033240	5	0.045
nucleobase containing small molecule metabolic process	GO:0055086	352	0.044
organonitrogen compound catabolic process	GO:1901565	264	0.044
regulation of secretion	GO:0051046	274	0.044
calcium ion homeostasis	GO:0055074	127	0.043
positive regulation of apoptotic process	GO:0043065	217	0.042	Mouse
camera type eye development	GO:0043010	266	0.042	Mouse
cation transport	GO:0006812	399	0.042
cellular response to lipid	GO:0071396	145	0.042
negative regulation of phosphorylation	GO:0042326	166	0.042
peptidyl amino acid modification	GO:0018193	336	0.041
striated muscle tissue development	GO:0014706	293	0.041	Mouse
purine nucleotide metabolic process	GO:0006163	302	0.041
female sex determination	GO:0030237	1	0.041
chemotaxis	GO:0006935	247	0.040
carbohydrate homeostasis	GO:0033500	128	0.040
kidney development	GO:0001822	213	0.039	Mouse
nucleoside phosphate catabolic process	GO:1901292	222	0.039
positive regulation of protein modification process	GO:0031401	299	0.039	Human Mouse
leukocyte differentiation	GO:0002521	342	0.039
regulation of hormone levels	GO:0010817	211	0.039
positive regulation of programmed cell death	GO:0043068	218	0.039	Mouse
nodal signaling pathway involved in determination of left right asymmetry	GO:0038107	2	0.039	Mouse
gland development	GO:0048732	330	0.039
aromatic compound catabolic process	GO:0019439	286	0.038
germ cell development	GO:0007281	185	0.038	Mouse
ion transmembrane transport	GO:0034220	361	0.038
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.038
kidney epithelium development	GO:0072073	121	0.038	Mouse
regulation of protein kinase activity	GO:0045859	232	0.037
developmental maturation	GO:0021700	193	0.037
regulation of tendon cell differentiation	GO:2001049	1	0.037
cell division	GO:0051301	120	0.037
dna metabolic process	GO:0006259	303	0.037	Worm
negative regulation of molecular function	GO:0044092	258	0.036
renal system vasculature development	GO:0061437	15	0.036
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.036
lung development	GO:0030324	164	0.036	Mouse
cellular response to organonitrogen compound	GO:0071417	145	0.036
nucleotide metabolic process	GO:0009117	332	0.035
regulation of ion transport	GO:0043269	215	0.035
stem cell development	GO:0048864	219	0.035	Mouse
regulation of secretion by cell	GO:1903530	249	0.035
divalent inorganic cation homeostasis	GO:0072507	138	0.035
regulation of mitotic cell cycle	GO:0007346	126	0.034
mitotic cell cycle	GO:0000278	195	0.034
negative regulation of phosphorus metabolic process	GO:0010563	184	0.034
cellular nitrogen compound catabolic process	GO:0044270	280	0.034
cellular lipid metabolic process	GO:0044255	323	0.034
reactive oxygen species metabolic process	GO:0072593	84	0.034
anatomical structure homeostasis	GO:0060249	145	0.033
chromatin modification	GO:0016568	187	0.033
ribonucleotide catabolic process	GO:0009261	208	0.033
placenta development	GO:0001890	140	0.033	Mouse
nuclear division	GO:0000280	158	0.033
organ growth	GO:0035265	117	0.033	Mouse Worm
metanephric mesenchyme morphogenesis	GO:0072133	4	0.033	Mouse
regulation of response to wounding	GO:1903034	189	0.032
glucose homeostasis	GO:0042593	128	0.032
negative regulation of intracellular signal transduction	GO:1902532	167	0.032
mesendoderm development	GO:0048382	3	0.032	Mouse
cellular metal ion homeostasis	GO:0006875	151	0.032	Mouse
skeletal system development	GO:0001501	356	0.032	Mouse
cytokine production	GO:0001816	319	0.031
response to amino acid	GO:0043200	37	0.031
multicellular organism growth	GO:0035264	161	0.031	Mouse Worm
purine ribonucleotide metabolic process	GO:0009150	290	0.031
mitotic cell cycle process	GO:1903047	159	0.031
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	GO:0072039	4	0.030	Mouse
ribonucleotide metabolic process	GO:0009259	291	0.030
purine containing compound catabolic process	GO:0072523	213	0.030
negative regulation of stem cell maintenance	GO:1902455	4	0.030	Mouse
carbohydrate derivative catabolic process	GO:1901136	231	0.030
cellular response to hormone stimulus	GO:0032870	150	0.030
purine nucleoside metabolic process	GO:0042278	241	0.030
nucleoside catabolic process	GO:0009164	206	0.030
digestive system development	GO:0055123	200	0.030	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.030
skin development	GO:0043588	220	0.030
negative regulation of prostatic bud formation	GO:0060686	4	0.030	Mouse
skeletal system morphogenesis	GO:0048705	203	0.029	Mouse
nucleoside metabolic process	GO:0009116	246	0.029
cellular response to acid chemical	GO:0071229	68	0.029
organonitrogen compound biosynthetic process	GO:1901566	192	0.029
ribonucleoside metabolic process	GO:0009119	245	0.029
positive regulation of transferase activity	GO:0051347	167	0.029
ossification	GO:0001503	216	0.029	Mouse
purine ribonucleotide catabolic process	GO:0009154	208	0.028
response to extracellular stimulus	GO:0009991	127	0.028	Mouse
nitrogen compound transport	GO:0071705	271	0.028
regulation of organelle organization	GO:0033043	289	0.028
purine nucleoside catabolic process	GO:0006152	205	0.028
hematopoietic progenitor cell differentiation	GO:0002244	143	0.028
endomembrane system organization	GO:0010256	147	0.028
nucleoside triphosphate catabolic process	GO:0009143	205	0.028
regulation of mapk cascade	GO:0043408	248	0.028	Mouse
glycosyl compound metabolic process	GO:1901657	246	0.028
female sex differentiation	GO:0046660	84	0.028
cellular calcium ion homeostasis	GO:0006874	119	0.028
axial mesodermal cell fate specification	GO:0048327	1	0.028	Mouse
positive regulation of dendrite development	GO:1900006	21	0.028
small gtpase mediated signal transduction	GO:0007264	97	0.027
neurotransmitter transport	GO:0006836	76	0.027
cellular response to amino acid stimulus	GO:0071230	29	0.027
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.027
negative regulation of cell development	GO:0010721	169	0.027	Mouse
positive regulation of nervous system development	GO:0051962	221	0.027
response to acid chemical	GO:0001101	111	0.027
respiratory system development	GO:0060541	190	0.027	Mouse
chondrocyte differentiation	GO:0002062	72	0.027	Mouse
positive regulation of cell development	GO:0010720	237	0.027
negative regulation of response to wounding	GO:1903035	77	0.027
positive regulation of protein phosphorylation	GO:0001934	242	0.027	Human Mouse
neural fold formation	GO:0001842	7	0.026	Mouse
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.026
male sex differentiation	GO:0046661	109	0.026	Mouse Worm
negative regulation of kinase activity	GO:0033673	81	0.026
cardiac cell development	GO:0055006	41	0.026	Mouse
regulation of cell division	GO:0051302	76	0.026
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.026
negative regulation of cellular protein metabolic process	GO:0032269	247	0.026
monocarboxylic acid metabolic process	GO:0032787	191	0.026
regulation of body fluid levels	GO:0050878	162	0.026
hormone secretion	GO:0046879	128	0.026
morphogenesis of a branching structure	GO:0001763	203	0.026
regulation of map kinase activity	GO:0043405	120	0.026
glomerulus development	GO:0032835	40	0.025
anion transport	GO:0006820	177	0.025
muscle adaptation	GO:0043500	39	0.025	Mouse
divalent inorganic cation transport	GO:0072511	178	0.025
divalent metal ion transport	GO:0070838	172	0.025
ameboidal type cell migration	GO:0001667	128	0.025	Mouse
myeloid leukocyte differentiation	GO:0002573	119	0.025
urogenital system development	GO:0001655	261	0.025	Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.025
cellular macromolecule catabolic process	GO:0044265	206	0.024
regulation of neurotransmitter levels	GO:0001505	87	0.024
positive regulation of growth	GO:0045927	104	0.024	Mouse Worm
regulation of neuron differentiation	GO:0045664	281	0.024
organic hydroxy compound metabolic process	GO:1901615	203	0.024
ear development	GO:0043583	200	0.024
glomerular mesangial cell development	GO:0072144	3	0.024
development of primary sexual characteristics	GO:0045137	143	0.024
circulatory system process	GO:0003013	197	0.024
apoptotic signaling pathway	GO:0097190	306	0.024
hormone metabolic process	GO:0042445	86	0.024
negative regulation of protein metabolic process	GO:0051248	282	0.024
purine nucleotide catabolic process	GO:0006195	211	0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.024	Human Mouse
meiotic nuclear division	GO:0007126	115	0.023
nephron development	GO:0072006	109	0.023	Mouse
locomotory behavior	GO:0007626	195	0.023
phospholipid metabolic process	GO:0006644	87	0.023
lateral inhibition	GO:0046331	1	0.023
negative regulation of nervous system development	GO:0051961	156	0.023	Mouse
cell adhesion	GO:0007155	329	0.023
ribonucleoside catabolic process	GO:0042454	206	0.023
membrane organization	GO:0061024	245	0.023
axonogenesis	GO:0007409	274	0.023
regulation of angiogenesis	GO:0045765	81	0.023	Mouse
negative regulation of phosphate metabolic process	GO:0045936	184	0.023
mesonephros development	GO:0001823	97	0.023	Mouse
negative regulation of cellular component organization	GO:0051129	194	0.023
glycosyl compound catabolic process	GO:1901658	206	0.023
adult locomotory behavior	GO:0008344	91	0.023
carbon catabolite repression of transcription from rna polymerase ii promoter	GO:0000437	1	0.023
kidney vasculature development	GO:0061440	15	0.023
negative regulation of cell proliferation	GO:0008285	296	0.023	Mouse
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.022
gonad development	GO:0008406	141	0.022
regionalization	GO:0003002	337	0.022	Mouse
regulation of transmembrane transport	GO:0034762	128	0.022
regulation of leukocyte differentiation	GO:1902105	159	0.022
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.022
female gonad development	GO:0008585	71	0.022
epithelial tube morphogenesis	GO:0060562	303	0.022
regulation of vasculature development	GO:1901342	88	0.022	Mouse
chromatin organization	GO:0006325	206	0.021
positive regulation of cell projection organization	GO:0031346	95	0.021
left lung morphogenesis	GO:0060460	3	0.021	Mouse
peptide secretion	GO:0002790	114	0.021
hexose metabolic process	GO:0019318	98	0.021
glycerophospholipid metabolic process	GO:0006650	71	0.021
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.021
cognition	GO:0050890	149	0.021
response to peptide hormone	GO:0043434	127	0.021
regulation of morphogenesis of a branching structure	GO:0060688	53	0.021	Mouse
organophosphate catabolic process	GO:0046434	232	0.021
inorganic ion transmembrane transport	GO:0098660	234	0.021
learning or memory	GO:0007611	148	0.021
meiotic cell cycle	GO:0051321	122	0.021
inorganic cation transmembrane transport	GO:0098662	207	0.021
regulation of system process	GO:0044057	200	0.021	Mouse
mitotic nuclear division	GO:0007067	48	0.021
macromolecule catabolic process	GO:0009057	281	0.021
limb development	GO:0060173	166	0.021	Mouse
microtubule cytoskeleton organization	GO:0000226	157	0.020
regulation of vascular wound healing	GO:0061043	2	0.020
regulation of peptide transport	GO:0090087	91	0.020
cytosolic calcium ion homeostasis	GO:0051480	70	0.020
regulation of membrane potential	GO:0042391	192	0.020
morphogenesis of a branching epithelium	GO:0061138	193	0.020
peptide transport	GO:0015833	133	0.020
spermatid differentiation	GO:0048515	115	0.020
protein processing	GO:0016485	163	0.020
neuronal action potential	GO:0019228	54	0.020
calcium ion transport	GO:0006816	159	0.020
oocyte axis specification	GO:0007309	2	0.020
bone morphogenesis	GO:0060349	78	0.020	Mouse
monosaccharide metabolic process	GO:0005996	106	0.020
endothelium development	GO:0003158	45	0.020	Mouse
polarity specification of proximal distal axis	GO:0010085	2	0.020	Mouse
glycerolipid metabolic process	GO:0046486	122	0.020
regulation of cell activation	GO:0050865	289	0.020
fertilization	GO:0009566	127	0.020
skeletal muscle organ development	GO:0060538	163	0.020
amide transport	GO:0042886	138	0.020
positive regulation of cell death	GO:0010942	224	0.019	Mouse
regulation of homeostatic process	GO:0032844	182	0.019	Mouse
organic anion transport	GO:0015711	137	0.019
extracellular structure organization	GO:0043062	148	0.019
plasma membrane organization	GO:0007009	90	0.019
cell growth	GO:0016049	130	0.019
cartilage development	GO:0051216	140	0.019	Mouse
mesenchymal cell apoptotic process involved in nephron morphogenesis	GO:1901145	4	0.019	Mouse
chemical homeostasis within a tissue	GO:0048875	9	0.019
development of primary male sexual characteristics	GO:0046546	88	0.019
heart morphogenesis	GO:0003007	178	0.019	Mouse
epidermis development	GO:0008544	187	0.019
wound healing	GO:0042060	157	0.019
paraxial mesodermal cell fate commitment	GO:0048343	2	0.019
pyramidal neuron migration	GO:0021852	1	0.019
glucose metabolic process	GO:0006006	92	0.019
synapse organization	GO:0050808	125	0.019
cellular response to peptide	GO:1901653	92	0.019
metanephric capsule specification	GO:0072267	1	0.019
cell type specific apoptotic process	GO:0097285	268	0.019	Mouse
glomerulus vasculature development	GO:0072012	14	0.019
peptide hormone secretion	GO:0030072	109	0.019
stem cell differentiation	GO:0048863	268	0.019	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.019
lymphocyte differentiation	GO:0030098	242	0.019
regulation of bmp signaling pathway	GO:0030510	60	0.019
epithelial cell proliferation	GO:0050673	174	0.019	Mouse
ovulation cycle	GO:0042698	59	0.019
blood circulation	GO:0008015	195	0.019
tissue homeostasis	GO:0001894	115	0.019
epithelial cell development	GO:0002064	159	0.019
mesenchyme development	GO:0060485	152	0.018	Mouse
rhythmic process	GO:0048511	174	0.018
microtubule based process	GO:0007017	236	0.018
cell fate commitment	GO:0045165	210	0.018
inflammatory response	GO:0006954	244	0.018	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	126	0.018
myeloid cell differentiation	GO:0030099	233	0.018
stem cell proliferation	GO:0072089	117	0.018	Mouse
cellular response to molecule of bacterial origin	GO:0071219	83	0.018
cation transmembrane transport	GO:0098655	266	0.018
regulation of t cell activation	GO:0050863	170	0.018
paraxial mesodermal cell differentiation	GO:0048342	2	0.018
negative regulation of immune system process	GO:0002683	209	0.018
regulation of anatomical structure size	GO:0090066	178	0.018	Worm
cerebellum development	GO:0021549	77	0.018
protein catabolic process	GO:0030163	221	0.018
glomerular mesangial cell differentiation	GO:0072008	3	0.018
regulation of lipid metabolic process	GO:0019216	118	0.017
negative regulation of neuron projection regeneration	GO:0070571	3	0.017
epithelial cell maturation involved in prostate gland development	GO:0060743	4	0.017
positive regulation of kinase activity	GO:0033674	155	0.017
innate immune response	GO:0045087	157	0.017	Worm
response to transforming growth factor beta	GO:0071559	88	0.017	Mouse
covalent chromatin modification	GO:0016569	163	0.017
protein maturation	GO:0051604	176	0.017
oxidation reduction process	GO:0055114	342	0.017
immune effector process	GO:0002252	321	0.017
regulation of ossification	GO:0030278	112	0.017
blastocyst development	GO:0001824	80	0.017	Mouse
leukocyte proliferation	GO:0070661	172	0.017
blood coagulation	GO:0007596	76	0.017
carbon catabolite repression of transcription	GO:0045013	1	0.017
nucleoside triphosphate metabolic process	GO:0009141	230	0.017
platelet derived growth factor receptor alpha signaling pathway	GO:0035790	3	0.017
protein modification by small protein conjugation or removal	GO:0070647	207	0.017
cardiac muscle tissue morphogenesis	GO:0055008	44	0.017	Mouse
platelet derived growth factor receptor signaling pathway	GO:0048008	32	0.017
cardiac muscle cell development	GO:0055013	39	0.017	Mouse
kidney morphogenesis	GO:0060993	83	0.017	Mouse
retina development in camera type eye	GO:0060041	119	0.017
cellular protein catabolic process	GO:0044257	155	0.017
regulation of cell cycle process	GO:0010564	160	0.017	Worm
single organism cell adhesion	GO:0098602	156	0.017
tendon formation	GO:0035992	4	0.017
cellular carbohydrate metabolic process	GO:0044262	119	0.017
tube formation	GO:0035148	140	0.017
carbon catabolite activation of transcription	GO:0045991	4	0.016
cellular response to lipopolysaccharide	GO:0071222	77	0.016
mesangial cell differentiation	GO:0072007	4	0.016
carbon catabolite activation of transcription from rna polymerase ii promoter	GO:0000436	4	0.016
spermatid development	GO:0007286	108	0.016
detection of glucose	GO:0051594	1	0.016
regulation of proteolysis	GO:0030162	164	0.016
tissue remodeling	GO:0048771	102	0.016
cardiac muscle tissue development	GO:0048738	130	0.016	Mouse
modification dependent macromolecule catabolic process	GO:0043632	133	0.016
endothelial cell differentiation	GO:0045446	41	0.016	Mouse
muscle system process	GO:0003012	141	0.016	Mouse
defense response to bacterium	GO:0042742	119	0.016	Worm
fat cell differentiation	GO:0045444	160	0.016	Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.016
regulation of neurotransmitter secretion	GO:0046928	29	0.016
regulation of stem cell proliferation	GO:0072091	78	0.016
adult behavior	GO:0030534	135	0.016
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.016
metencephalon development	GO:0022037	89	0.016
response to steroid hormone	GO:0048545	56	0.016
regulation of organ morphogenesis	GO:2000027	144	0.016	Mouse
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.016
ovarian follicle development	GO:0001541	40	0.016
organophosphate biosynthetic process	GO:0090407	122	0.016
regulation of apoptotic signaling pathway	GO:2001233	197	0.016
bmp signaling pathway	GO:0030509	93	0.016
energy homeostasis	GO:0097009	15	0.016	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.016	Mouse
cellular response to steroid hormone stimulus	GO:0071383	33	0.015
nucleotide catabolic process	GO:0009166	217	0.015
regulation of phospholipase c activity	GO:1900274	3	0.015
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.015
positive regulation of protein kinase activity	GO:0045860	144	0.015
nucleoside phosphate biosynthetic process	GO:1901293	79	0.015
hemostasis	GO:0007599	78	0.015
lipid localization	GO:0010876	126	0.015
regulation of hydrolase activity	GO:0051336	246	0.015
cellular modified amino acid metabolic process	GO:0006575	63	0.015
positive regulation of stem cell proliferation	GO:2000648	59	0.015
pattern specification involved in metanephros development	GO:0072268	4	0.015
positive regulation of cell adhesion	GO:0045785	80	0.015
biomineral tissue development	GO:0031214	64	0.015
positive regulation of hydrolase activity	GO:0051345	148	0.015
regulation of carbohydrate metabolic process	GO:0006109	75	0.015
striated muscle cell development	GO:0055002	125	0.015	Mouse
transmission of nerve impulse	GO:0019226	76	0.015
oocyte construction	GO:0007308	2	0.015
regulation of heart growth	GO:0060420	31	0.015	Mouse
maternal placenta development	GO:0001893	20	0.015	Mouse
negative regulation of map kinase activity	GO:0043407	34	0.015
cardiac muscle cell proliferation	GO:0060038	31	0.015	Mouse
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.015
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.015
response to molecule of bacterial origin	GO:0002237	143	0.015
regulation of lymphocyte activation	GO:0051249	240	0.015
peptidyl tyrosine modification	GO:0018212	145	0.015
cellular response to peptide hormone stimulus	GO:0071375	92	0.015
inner ear morphogenesis	GO:0042472	101	0.015
regulation of nuclear division	GO:0051783	56	0.015
nephron epithelium morphogenesis	GO:0072088	68	0.015
cellular response to extracellular stimulus	GO:0031668	81	0.015
nephron tubule morphogenesis	GO:0072078	68	0.015
protein localization to organelle	GO:0033365	185	0.015
response to peptide	GO:1901652	136	0.015
sensory perception	GO:0007600	245	0.015
regulation of stem cell differentiation	GO:2000736	50	0.014	Mouse
positive regulation of neuron projection development	GO:0010976	79	0.014
ureteric bud development	GO:0001657	94	0.014	Mouse
negative regulation of synapse assembly	GO:0051964	3	0.014
regulation of muscle system process	GO:0090257	80	0.014	Mouse
cellular response to cytokine stimulus	GO:0071345	189	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
response to temperature stimulus	GO:0009266	55	0.014
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.014
forebrain development	GO:0030900	302	0.014
negative regulation of neuron differentiation	GO:0045665	101	0.014	Mouse
positive regulation of transcription from rna polymerase ii promoter by glucose	GO:0000432	3	0.014
neuron death	GO:0070997	154	0.014
mesonephric tubule development	GO:0072164	94	0.014	Mouse
respiratory tube development	GO:0030323	167	0.014	Mouse
negative regulation of cellular amine metabolic process	GO:0033239	1	0.014
regulation of glucose metabolic process	GO:0010906	60	0.014
embryonic organ morphogenesis	GO:0048562	276	0.014	Mouse
glomerular mesangial cell proliferation	GO:0072110	3	0.014
protein localization to nucleus	GO:0034504	121	0.014
cellular response to organic cyclic compound	GO:0071407	87	0.014
transcription from rna polymerase iii promoter	GO:0006383	3	0.014
cardiac ventricle development	GO:0003231	83	0.014	Mouse
negative regulation of mitotic cell cycle	GO:0045930	58	0.014
cellular response to biotic stimulus	GO:0071216	92	0.014
learning	GO:0007612	98	0.014
development of primary female sexual characteristics	GO:0046545	73	0.014
compound eye development	GO:0048749	1	0.014
protein ubiquitination	GO:0016567	171	0.014
positive regulation of ion transport	GO:0043270	65	0.014
multi multicellular organism process	GO:0044706	109	0.014	Mouse
peptidyl tyrosine phosphorylation	GO:0018108	143	0.014
response to organic cyclic compound	GO:0014070	198	0.014
liver development	GO:0001889	66	0.014	Mouse
heart trabecula morphogenesis	GO:0061384	26	0.014	Mouse
regulation of peptide secretion	GO:0002791	77	0.014
regulation of tissue remodeling	GO:0034103	38	0.014
primary neural tube formation	GO:0014020	95	0.014	Mouse
regulation of cell adhesion	GO:0030155	154	0.013
apoptotic process involved in outflow tract morphogenesis	GO:0003275	2	0.013
negative regulation of cell activation	GO:0050866	111	0.013
negative regulation of mapk cascade	GO:0043409	65	0.013
regulation of endothelial cell proliferation	GO:0001936	23	0.013	Mouse
regulation of purine nucleotide metabolic process	GO:1900542	169	0.013
regulation of neurotransmitter transport	GO:0051588	35	0.013
mesonephric epithelium development	GO:0072163	94	0.013	Mouse
negative regulation of protein modification process	GO:0031400	163	0.013
regulation of ion transmembrane transport	GO:0034765	119	0.013
nephron tubule development	GO:0072080	84	0.013
t cell activation	GO:0042110	289	0.013
multicellular organismal signaling	GO:0035637	91	0.013
nodal signaling pathway	GO:0038092	10	0.013	Mouse
purine ribonucleoside catabolic process	GO:0046130	205	0.013
metanephric mesenchymal cell proliferation involved in metanephros development	GO:0072136	2	0.013	Mouse
developmental programmed cell death	GO:0010623	41	0.013	Mouse
mesangial cell development	GO:0072143	4	0.013
response to monosaccharide	GO:0034284	67	0.013
positive regulation of angiogenesis	GO:0045766	46	0.013	Mouse
response to oxygen levels	GO:0070482	62	0.013
neural tube formation	GO:0001841	108	0.013
cerebellar cortex development	GO:0021695	48	0.013
cell maturation	GO:0048469	127	0.013
ectoderm formation	GO:0001705	3	0.013
extracellular matrix organization	GO:0030198	147	0.013
negative regulation of hormone metabolic process	GO:0032351	4	0.013
ear morphogenesis	GO:0042471	118	0.013
adrenal gland development	GO:0030325	18	0.013
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.013
prostate gland stromal morphogenesis	GO:0060741	2	0.013
cellular transition metal ion homeostasis	GO:0046916	32	0.013	Mouse
mesonephric tubule morphogenesis	GO:0072171	63	0.013
pallium development	GO:0021543	120	0.013
modification dependent protein catabolic process	GO:0019941	133	0.013
regulation of nucleotide metabolic process	GO:0006140	169	0.013
striated muscle cell proliferation	GO:0014855	39	0.012	Mouse
megakaryocyte differentiation	GO:0030219	26	0.012
response to insulin	GO:0032868	100	0.012
response to increased oxygen levels	GO:0036296	2	0.012
axon ensheathment	GO:0008366	76	0.012
nephron morphogenesis	GO:0072028	69	0.012	Mouse
ras protein signal transduction	GO:0007265	77	0.012
carbon catabolite regulation of transcription	GO:0045990	4	0.012
posttranscriptional regulation of gene expression	GO:0010608	155	0.012
regulation of lipid transport	GO:0032368	36	0.012
response to lipopolysaccharide	GO:0032496	128	0.012
renal capsule morphogenesis	GO:0072128	1	0.012

Gdf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.026
disease of anatomical entity	DOID:7	0.026
disease of cellular proliferation	DOID:14566	0.023
cancer	DOID:162	0.021
organ system cancer	DOID:0050686	0.020
sensory system disease	DOID:0050155	0.016

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