Mus musculus

99 known processes

Calr

calreticulin

(Aliases: Calregulin,CRT)

Calr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to endoplasmic reticulum stressGO:0034976530.292
Worm
response to topologically incorrect proteinGO:0035966250.247
Worm
apoptotic signaling pathwayGO:00971903060.228
er nucleus signaling pathwayGO:0006984270.226
Worm
glycoprotein biosynthetic processGO:0009101890.222
cellular response to topologically incorrect proteinGO:0035967250.217
Worm
spermatogenesisGO:00072832840.194
Rat
protein glycosylationGO:0006486550.163
proteasomal protein catabolic processGO:0010498980.151
protein hydroxylationGO:001812640.148
peptidyl amino acid modificationGO:00181933360.146
endoplasmic reticulum unfolded protein responseGO:0030968190.144
Worm
cellular amino acid metabolic processGO:00065201030.139
regulation of apoptotic signaling pathwayGO:20012331970.127
macromolecule glycosylationGO:0043413550.122
endocytosisGO:00068971680.119
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.115
glycoprotein metabolic processGO:00091001160.110
protein n linked glycosylationGO:0006487120.106
transmembrane transportGO:00550854120.105
peptidyl proline hydroxylation to 4 hydroxy l prolineGO:001840120.095
lateral inhibitionGO:004633110.091
male gamete generationGO:00482322850.087
Rat
modification dependent protein catabolic processGO:00199411330.075
cellular protein catabolic processGO:00442571550.074
extrinsic apoptotic signaling pathwayGO:00971911260.073
glycosylationGO:0070085620.073
spermatid differentiationGO:00485151150.072
positive regulation of cell deathGO:00109422240.071
carbohydrate derivative biosynthetic processGO:19011371830.071
positive regulation of programmed cell deathGO:00430682180.068
alpha amino acid metabolic processGO:1901605590.066
spermatid developmentGO:00072861080.064
4 hydroxyproline metabolic processGO:001947150.064
endoplasmic reticulum calcium ion homeostasisGO:0032469110.063
regulation of cellular amino acid metabolic processGO:000652150.060
amine metabolic processGO:0009308450.059
cellular macromolecule catabolic processGO:00442652060.059
response to unfolded proteinGO:0006986210.058
Worm
posttranscriptional regulation of gene expressionGO:00106081550.058
cation homeostasisGO:00550802120.058
regulation of cellular response to stressGO:00801351590.057
regulation of transferase activityGO:00513382630.056
body morphogenesisGO:0010171450.055
germ cell developmentGO:00072811850.052
protein catabolic processGO:00301632210.052
cellular amine metabolic processGO:0044106440.052
modification dependent macromolecule catabolic processGO:00436321330.052
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.051
digestive tract developmentGO:00485651900.050
regulation of cell migrationGO:00303342190.048
Human
carbohydrate metabolic processGO:00059752300.047
circulatory system processGO:00030131970.047
vascular process in circulatory systemGO:0003018620.046
regulation of cellular ketone metabolic processGO:0010565660.042
regulation of resting membrane potentialGO:006007530.041
intrinsic apoptotic signaling pathwayGO:00971931320.041
positive regulation of necrotic cell deathGO:001094010.040
response to oxygen levelsGO:0070482620.040
monocarboxylic acid metabolic processGO:00327871910.039
regulation of kinase activityGO:00435492490.039
cation transportGO:00068123990.039
cellular homeostasisGO:00197252400.039
peptidyl asparagine modificationGO:001819610.038
response to organonitrogen compoundGO:00102432460.037
leukocyte proliferationGO:00706611720.036
epithelial cell proliferationGO:00506731740.035
metal ion homeostasisGO:00550651890.035
oxidation reduction processGO:00551143420.035
protein localization to organelleGO:00333651850.034
vacuole organizationGO:0007033380.034
digestive system developmentGO:00551232000.034
response to hypoxiaGO:0001666580.034
protein modification by small protein conjugationGO:00324461870.034
ubiquitin dependent protein catabolic processGO:00065111290.034
maintenance of locationGO:0051235890.033
proteolysis involved in cellular protein catabolic processGO:00516031470.033
leukocyte differentiationGO:00025213420.032
response to decreased oxygen levelsGO:0036293590.031
positive regulation of apoptotic processGO:00430652170.031
positive regulation of protein phosphorylationGO:00019342420.031
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.030
negative regulation of cellular protein metabolic processGO:00322692470.030
Rat
peptidyl proline modificationGO:001820860.030
peptide metabolic processGO:0006518460.030
midgut developmentGO:000749440.030
cellular ketone metabolic processGO:0042180840.029
ion transmembrane transportGO:00342203610.029
inorganic ion transmembrane transportGO:00986602340.029
er associated ubiquitin dependent protein catabolic processGO:0030433100.029
protein modification by small protein conjugation or removalGO:00706472070.028
cation transmembrane transportGO:00986552660.028
kidney developmentGO:00018222130.028
cell growthGO:00160491300.027
positive regulation of protein modification processGO:00314012990.027
mrna metabolic processGO:0016071840.026
gland developmentGO:00487323300.026
organonitrogen compound biosynthetic processGO:19015661920.026
cellular chemical homeostasisGO:00550822150.026
nitrogen compound transportGO:00717052710.026
renal system developmentGO:00720012250.026
cellular ion homeostasisGO:00068731650.026
epithelial cell developmentGO:00020641590.025
regulation of multi organism processGO:00439001110.025
muscle cell differentiationGO:00426922610.025
Rat
fertilizationGO:00095661270.025
choline transportGO:001587130.025
skeletal system developmentGO:00015013560.025
protein ubiquitinationGO:00165671710.025
copper ion transportGO:0006825100.025
urogenital system developmentGO:00016552610.025
forebrain developmentGO:00309003020.025
regulation of epidermal growth factor activated receptor activityGO:000717670.025
positive regulation of kinase activityGO:00336741550.025
regulation of cellular amine metabolic processGO:0033238200.025
cellular modified amino acid metabolic processGO:0006575630.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
regulation of vesicle mediated transportGO:00606271390.024
positive regulation of transferase activityGO:00513471670.024
receptor mediated endocytosisGO:0006898510.024
cellular divalent inorganic cation homeostasisGO:00725031270.023
skin developmentGO:00435882200.023
cell adhesionGO:00071553290.023
Human
regulation of protein kinase activityGO:00458592320.022
divalent metal ion transportGO:00708381720.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
cell type specific apoptotic processGO:00972852680.021
macromolecule catabolic processGO:00090572810.021
divalent inorganic cation transportGO:00725111780.021
muscle system processGO:00030121410.021
protein maturationGO:00516041760.021
single organismal cell cell adhesionGO:00163371310.020
regulation of neuron differentiationGO:00456642810.020
Human
cellular response to antibioticGO:007123640.020
regulation of secretionGO:00510462740.020
mapk cascadeGO:00001652810.020
ear developmentGO:00435832000.019
cellular response to oxidative stressGO:0034599760.019
protein foldingGO:0006457280.019
Mouse Rat
negative regulation of protein tyrosine kinase activityGO:006109930.019
positive regulation of cellular amine metabolic processGO:003324050.019
blood circulationGO:00080151950.019
zygotic determination of anterior posterior axis embryoGO:000735430.019
cellular calcium ion homeostasisGO:00068741190.019
immune effector processGO:00022523210.019
inorganic cation transmembrane transportGO:00986622070.018
compound eye developmentGO:004874910.018
epidermis developmentGO:00085441870.018
nucleotide metabolic processGO:00091173320.018
chromatin organizationGO:00063252060.018
pharynx developmentGO:006046510.018
negative regulation of cellular amino acid metabolic processGO:004576300.018
extracellular structure organizationGO:00430621480.018
lymphocyte activation involved in immune responseGO:0002285930.018
cellular response to hormone stimulusGO:00328701500.018
negative regulation of protein modification processGO:00314001630.018
notch receptor processingGO:000722040.018
positive regulation of hydrolase activityGO:00513451480.017
nucleobase containing small molecule metabolic processGO:00550863520.017
purine containing compound metabolic processGO:00725213110.017
ras protein signal transductionGO:0007265770.017
regulation of ion transportGO:00432692150.017
developmental maturationGO:00217001930.017
small gtpase mediated signal transductionGO:0007264970.017
synaptic transmissionGO:00072683290.017
digestive tract morphogenesisGO:00485461470.017
lipid localizationGO:00108761260.017
cellular response to interleukin 4GO:0071353210.016
cellular response to organonitrogen compoundGO:00714171450.016
cellular response to growth factor stimulusGO:00713631970.016
substantia nigra developmentGO:002176220.016
divalent inorganic cation homeostasisGO:00725071380.016
response to oxidative stressGO:00069791230.016
regulation of transmembrane transportGO:00347621280.016
peptidyl tyrosine modificationGO:00182121450.016
actin cytoskeleton organizationGO:00300362200.016
second messenger mediated signalingGO:0019932730.016
nucleoside phosphate metabolic processGO:00067533380.016
cellular lipid metabolic processGO:00442553230.016
cellular response to lipidGO:00713961450.016
mrna processingGO:0006397630.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
regulation of tube sizeGO:0035150570.016
regulation of cell motilityGO:20001452360.015
Human
positive regulation of protein kinase activityGO:00458601440.015
response to organic cyclic compoundGO:00140701980.015
Rat
cell fate commitmentGO:00451652100.015
cellular amide metabolic processGO:0043603580.015
positive regulation of growthGO:00459271040.015
regulation of mapk cascadeGO:00434082480.015
cellular component assembly involved in morphogenesisGO:00109271390.015
embryonic organ morphogenesisGO:00485622760.015
cell activation involved in immune responseGO:00022631260.015
negative regulation of molecular functionGO:00440922580.015
regulation of blood pressureGO:0008217930.015
regulation of anatomical structure sizeGO:00900661780.015
regulation of phosphoprotein phosphatase activityGO:004366630.015
translationGO:0006412930.015
Rat
positive regulation of apoptotic signaling pathwayGO:2001235950.014
calcium ion homeostasisGO:00550741270.014
organic hydroxy compound metabolic processGO:19016152030.014
placenta developmentGO:00018901400.014
negative regulation of nervous system developmentGO:00519611560.014
Human
positive regulation of cell migrationGO:00303351090.014
Human
photoreceptor cell morphogenesisGO:000859430.014
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.014
calcium ion transportGO:00068161590.014
muscle tissue developmentGO:00605373080.014
Rat
cytokinetic processGO:003250620.014
exocytosisGO:00068871210.014
response to lipopolysaccharideGO:00324961280.014
regulation of hydrolase activityGO:00513362460.014
stem cell differentiationGO:00488632680.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
regulation of receptor activityGO:0010469410.014
regulation of lymphocyte activationGO:00512492400.014
oocyte axis specificationGO:000730920.014
regulation of establishment of protein localizationGO:00702011810.014
muscle contractionGO:00069361010.014
regulation of translationGO:0006417710.014
Rat
t cell activationGO:00421102890.014
actin filament organizationGO:00070151130.013
inflammatory responseGO:00069542440.013
dephosphorylationGO:00163111290.013
regulation of ion transmembrane transportGO:00347651190.013
fatty acid metabolic processGO:00066311210.013
steroid metabolic processGO:00082021190.013
meiotic nuclear divisionGO:00071261150.013
response to extracellular stimulusGO:00099911270.013
protein targetingGO:00066051430.013
organic acid transportGO:00158491010.013
carbohydrate homeostasisGO:00335001280.013
negative regulation of protein metabolic processGO:00512482820.013
Rat
microtubule based processGO:00070172360.013
cellular response to decreased oxygen levelsGO:0036294180.013
immune response regulating signaling pathwayGO:00027641250.013
blastocyst developmentGO:0001824800.013
regulation of phagocytosisGO:0050764330.013
protein localization to membraneGO:00726571080.013
neuron deathGO:00709971540.013
sensory organ morphogenesisGO:00905962420.013
regulation of response to oxidative stressGO:1902882190.013
cytokine productionGO:00018163190.013
positive regulation of protein transportGO:0051222930.013
purine nucleoside metabolic processGO:00422782410.013
regulation of body fluid levelsGO:00508781620.013
regulation of cell projection organizationGO:00313442060.013
axonogenesisGO:00074092740.013
extracellular matrix organizationGO:00301981470.012
defense response to other organismGO:00985421970.012
cytoskeleton dependent intracellular transportGO:0030705500.012
organic hydroxy compound transportGO:0015850930.012
oocyte constructionGO:000730820.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.012
protein targeting to erGO:004504720.012
negative regulation of phosphorus metabolic processGO:00105631840.012
small molecule biosynthetic processGO:00442831320.012
establishment of vesicle localizationGO:0051650810.012
microtubule based movementGO:0007018840.012
regulation of neurotransmitter levelsGO:0001505870.012
lipoprotein metabolic processGO:0042157430.012
organonitrogen compound catabolic processGO:19015652640.012
purine containing compound catabolic processGO:00725232130.012
immunoglobulin productionGO:0002377730.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
multicellular organismal homeostasisGO:00488711640.012
purine ribonucleotide metabolic processGO:00091502900.012
negative regulation of phosphate metabolic processGO:00459361840.012
response to molecule of bacterial originGO:00022371430.012
cellular response to molecule of bacterial originGO:0071219830.012
purine nucleotide metabolic processGO:00061633020.012
retrograde transport endosome to golgiGO:004214720.012
regulation of system processGO:00440572000.012
cellularizationGO:000734910.012
cellular metal ion homeostasisGO:00068751510.012
protein n linked glycosylation via asparagineGO:001827910.012
defense response to gram positive bacteriumGO:0050830500.012
regulation of hormone levelsGO:00108172110.012
b cell activationGO:00421131610.012
ameboidal type cell migrationGO:00016671280.012
leukocyte activation involved in immune responseGO:00023661260.012
response to acid chemicalGO:00011011110.012
autophagyGO:0006914450.012
learning or memoryGO:00076111480.012
mesoderm developmentGO:00074981000.011
positive regulation of cell activationGO:00508671580.011
response to growth factorGO:00708481980.011
heart morphogenesisGO:00030071780.011
nucleotide sugar metabolic processGO:000922540.011
tube formationGO:00351481400.011
regulation of protein serine threonine kinase activityGO:00719001570.011
neural tube developmentGO:00219151600.011
cellular response to external stimulusGO:0071496880.011
neuron apoptotic processGO:00514021420.011
embryonic limb morphogenesisGO:00303261260.011
cellular response to extracellular stimulusGO:0031668810.011
regulation of cellular catabolic processGO:00313292420.011
regulation of cellular component biogenesisGO:00440871810.011
negative regulation of cellular component organizationGO:00511291940.011
multi multicellular organism processGO:00447061090.011
production of molecular mediator of immune responseGO:00024401030.011
ossificationGO:00015032160.011
peptidyl tyrosine phosphorylationGO:00181081430.011
carboxylic acid transportGO:00469421000.011
lymphocyte differentiationGO:00300982420.011
nucleoside triphosphate catabolic processGO:00091432050.011
endodermal digestive tract morphogenesisGO:006103140.011
cellular response to lipopolysaccharideGO:0071222770.011
regulation of cytokine productionGO:00018172660.011
regulation of ossificationGO:00302781120.011
regulation of epithelial cell proliferationGO:00506781410.011
cellular response to biotic stimulusGO:0071216920.011
lymphocyte proliferationGO:00466511640.011
negative regulation of cell projection organizationGO:0031345560.011
membrane organizationGO:00610242450.011
regulation of endocytosisGO:0030100690.011
organic acid biosynthetic processGO:0016053860.011
establishment of synaptic vesicle localizationGO:0097480570.011
heterochromatin organizationGO:007082840.011
negative regulation of response to endoplasmic reticulum stressGO:190357380.011
positive regulation of cell motilityGO:20001471160.011
Human
ribonucleotide metabolic processGO:00092592910.011
regulation of neuron projection developmentGO:00109751690.011
negative regulation of intracellular signal transductionGO:19025321670.011
t cell proliferationGO:00420981200.011
negative regulation of protein phosphorylationGO:00019331260.011
mesenchymal cell differentiationGO:00487621070.011
male sex differentiationGO:00466611090.011
adult behaviorGO:00305341350.011
mesenchyme developmentGO:00604851520.011
protein secretionGO:00093061110.011
cell maturationGO:00484691270.010
gonad developmentGO:00084061410.010
cellular protein complex assemblyGO:00436231160.010
regulation of cellular response to oxidative stressGO:1900407190.010
negative regulation of cellular amine metabolic processGO:003323910.010
ribonucleoside metabolic processGO:00091192450.010
myotube cell developmentGO:0014904600.010
response to peptide hormoneGO:00434341270.010
myeloid leukocyte differentiationGO:00025731190.010
fat cell differentiationGO:00454441600.010
regulation of bindingGO:00510981110.010
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.010
skeletal system morphogenesisGO:00487052030.010
negative regulation of neuron projection developmentGO:0010977500.010
negative regulation of epidermal growth factor activated receptor activityGO:000717530.010

Calr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.051
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.040
central nervous system diseaseDOID:33100.040
connective tissue diseaseDOID:6500.039
musculoskeletal system diseaseDOID:1700.039
cardiovascular system diseaseDOID:128700.037
muscle tissue diseaseDOID:6600.037
cardiomyopathyDOID:005070000.037
myopathyDOID:42300.037
muscular diseaseDOID:008000000.037
heart diseaseDOID:11400.037
integumentary system diseaseDOID:1600.035
neurodegenerative diseaseDOID:128900.031
tauopathyDOID:68000.031
inherited metabolic disorderDOID:65500.027
disease of mental healthDOID:15000.025
dementiaDOID:130700.025
alzheimer s diseaseDOID:1065200.025
cognitive disorderDOID:156100.025
bone diseaseDOID:008000100.023
acquired metabolic diseaseDOID:006015800.022
intrinsic cardiomyopathyDOID:006003600.020
neuropathyDOID:87000.015
skin diseaseDOID:3700.015
bone development diseaseDOID:008000600.013
dilated cardiomyopathyDOID:1293000.013
sensory system diseaseDOID:005015500.012
immune system diseaseDOID:291400.010