Mus musculus

69 known processes

Phb

prohibitin

(Aliases: Bap32)

Phb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleoside triphosphate metabolic processGO:00091412300.750
Worm
mitochondrion organizationGO:00070051340.692
Worm
purine ribonucleotide metabolic processGO:00091502900.527
Worm
nucleoside phosphate metabolic processGO:00067533380.457
Worm
atp metabolic processGO:0046034750.373
Worm
nucleoside metabolic processGO:00091162460.355
Worm
regulation of oxidative phosphorylationGO:000208260.333
Worm
ribonucleoside metabolic processGO:00091192450.321
Worm
purine nucleotide metabolic processGO:00061633020.297
Worm
purine ribonucleoside triphosphate metabolic processGO:00092052200.272
Worm
glycosyl compound metabolic processGO:19016572460.259
Worm
nucleotide metabolic processGO:00091173320.251
Worm
purine containing compound metabolic processGO:00725213110.215
Worm
purine ribonucleoside metabolic processGO:00461282410.203
Worm
nucleobase containing small molecule metabolic processGO:00550863520.192
Worm
regulation of nucleoside metabolic processGO:00091181300.188
Worm
purine nucleoside monophosphate metabolic processGO:0009126810.186
Worm
ribonucleoside triphosphate metabolic processGO:00091992200.176
Worm
ribose phosphate metabolic processGO:00196932910.167
Worm
regulation of membrane potentialGO:00423911920.152
purine nucleoside triphosphate metabolic processGO:00091442260.150
Worm
transmembrane transportGO:00550854120.143
heterocycle catabolic processGO:00467002800.143
purine ribonucleoside monophosphate metabolic processGO:0009167800.138
Worm
regulation of nucleotide metabolic processGO:00061401690.122
Worm
development of primary sexual characteristicsGO:00451371430.110
Worm
ribonucleotide metabolic processGO:00092592910.110
Worm
oxidation reduction processGO:00551143420.097
positive regulation of purine nucleotide metabolic processGO:19005441140.095
aromatic compound catabolic processGO:00194392860.094
purine nucleoside metabolic processGO:00422782410.093
Worm
nucleoside monophosphate metabolic processGO:0009123850.092
Worm
synaptic transmissionGO:00072683290.087
positive regulation of cellular respirationGO:190185730.087
regulation of purine nucleotide metabolic processGO:19005421690.086
Worm
inorganic ion transmembrane transportGO:00986602340.086
small molecule catabolic processGO:0044282710.081
cellular amino acid metabolic processGO:00065201030.078
positive regulation of nucleoside metabolic processGO:0045979910.078
nucleoside triphosphate catabolic processGO:00091432050.074
protein processingGO:00164851630.073
regulation of apoptotic signaling pathwayGO:20012331970.069
defecationGO:003042110.062
Worm
cellular respirationGO:0045333380.060
cellular nitrogen compound catabolic processGO:00442702800.059
generation of precursor metabolites and energyGO:00060911030.058
Worm
cellular homeostasisGO:00197252400.058
nucleoside phosphate catabolic processGO:19012922220.057
cation transmembrane transportGO:00986552660.056
organonitrogen compound catabolic processGO:19015652640.056
response to oxidative stressGO:00069791230.055
Worm
apoptotic signaling pathwayGO:00971903060.055
calcium ion homeostasisGO:00550741270.054
purine ribonucleoside catabolic processGO:00461302050.054
cation homeostasisGO:00550802120.051
cellular metal ion homeostasisGO:00068751510.051
cation transportGO:00068123990.051
regulation of ion transportGO:00432692150.050
metal ion homeostasisGO:00550651890.050
ribose phosphate biosynthetic processGO:0046390590.049
regulation of hydrolase activityGO:00513362460.049
iron sulfur cluster assemblyGO:001622630.044
negative regulation of organelle organizationGO:0010639900.044
regulation of cellular amino acid metabolic processGO:000652150.044
purine ribonucleotide biosynthetic processGO:0009152590.044
purine nucleotide biosynthetic processGO:0006164650.043
coenzyme metabolic processGO:0006732520.043
cellular calcium ion homeostasisGO:00068741190.042
reactive oxygen species metabolic processGO:0072593840.042
gland developmentGO:00487323300.041
cytokine productionGO:00018163190.041
nucleoside phosphate biosynthetic processGO:1901293790.040
nucleotide catabolic processGO:00091662170.039
gtp metabolic processGO:00460391440.039
cellular ion homeostasisGO:00068731650.039
gonad developmentGO:00084061410.039
Worm
positive regulation of cellular amino acid metabolic processGO:004576430.039
ribonucleoside monophosphate metabolic processGO:0009161800.039
Worm
regulation of organelle organizationGO:00330432890.038
carbohydrate derivative catabolic processGO:19011362310.038
organic cyclic compound catabolic processGO:19013612950.037
negative regulation of cellular component organizationGO:00511291940.036
response to superoxideGO:0000303160.036
organophosphate catabolic processGO:00464342320.036
alpha amino acid metabolic processGO:1901605590.035
spermatogenesisGO:00072832840.035
Worm
hydrogen transportGO:0006818350.035
membrane organizationGO:00610242450.035
ribonucleoside monophosphate biosynthetic processGO:000915690.035
regulation of inflammatory responseGO:00507271470.034
adult behaviorGO:00305341350.034
gtp catabolic processGO:00061841430.034
regulation of cellular amine metabolic processGO:0033238200.033
positive regulation of nucleotide metabolic processGO:00459811140.032
response to oxygen radicalGO:0000305160.032
positive regulation of apoptotic processGO:00430652170.032
positive regulation of hydrolase activityGO:00513451480.031
purine ribonucleotide catabolic processGO:00091542080.031
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.030
ribonucleoside catabolic processGO:00424542060.030
ribonucleotide catabolic processGO:00092612080.030
macromolecule catabolic processGO:00090572810.030
cellular protein complex assemblyGO:00436231160.030
intrinsic apoptotic signaling pathwayGO:00971931320.030
organonitrogen compound biosynthetic processGO:19015661920.030
cellular ketone metabolic processGO:0042180840.030
regulation of cysteine type endopeptidase activityGO:2000116650.029
inorganic cation transmembrane transportGO:00986622070.029
intracellular steroid hormone receptor signaling pathwayGO:0030518290.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.028
male gamete generationGO:00482322850.028
Worm
cellular response to oxidative stressGO:0034599760.028
oxidative phosphorylationGO:0006119140.027
Worm
ribonucleotide biosynthetic processGO:0009260590.027
muscle cell developmentGO:00550011330.027
regulation of cellular ketone metabolic processGO:0010565660.027
nucleoside catabolic processGO:00091642060.026
purine containing compound biosynthetic processGO:0072522700.026
locomotory behaviorGO:00076261950.026
intracellular receptor signaling pathwayGO:0030522740.026
purine nucleoside triphosphate catabolic processGO:00091462030.025
guanosine containing compound metabolic processGO:19010681440.025
divalent inorganic cation homeostasisGO:00725071380.025
response to organonitrogen compoundGO:00102432460.025
peptidyl amino acid modificationGO:00181933360.024
positive regulation of cellular amine metabolic processGO:003324050.024
intracellular protein transportGO:00068862040.024
sensory perceptionGO:00076002450.024
inflammatory responseGO:00069542440.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
cellular lipid metabolic processGO:00442553230.024
catecholamine metabolic processGO:0006584300.023
regulation of lymphocyte activationGO:00512492400.023
negative regulation of phosphorylationGO:00423261660.023
regulation of transporter activityGO:0032409570.023
protein localization to organelleGO:00333651850.023
mitochondrial dna replicationGO:000626470.023
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
interleukin 8 productionGO:003263740.022
carbohydrate derivative biosynthetic processGO:19011371830.022
proteasomal protein catabolic processGO:0010498980.022
positive regulation of programmed cell deathGO:00430682180.022
proton transportGO:0015992350.022
positive regulation of protein modification processGO:00314012990.022
reactive oxygen species biosynthetic processGO:190340980.021
germ cell developmentGO:00072811850.021
Worm
cytoplasmic transportGO:00164822340.021
regulation of hormone levelsGO:00108172110.021
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.021
t cell activationGO:00421102890.021
purine nucleoside monophosphate biosynthetic processGO:000912790.021
small molecule biosynthetic processGO:00442831320.021
cellular divalent inorganic cation homeostasisGO:00725031270.020
negative regulation of apoptotic signaling pathwayGO:20012341040.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
cellular amine metabolic processGO:0044106440.020
amine metabolic processGO:0009308450.020
regulation of transferase activityGO:00513382630.020
cellular chemical homeostasisGO:00550822150.020
regulation of reactive oxygen species biosynthetic processGO:190342620.020
cofactor metabolic processGO:0051186800.020
cellular aldehyde metabolic processGO:0006081120.019
purine nucleotide catabolic processGO:00061952110.019
muscle cell differentiationGO:00426922610.019
negative regulation of intracellular signal transductionGO:19025321670.019
protein maturationGO:00516041760.019
regulation of purine nucleotide catabolic processGO:00331211220.019
regulation of cytokine productionGO:00018172660.019
endocytosisGO:00068971680.018
purine nucleoside catabolic processGO:00061522050.018
organophosphate biosynthetic processGO:00904071220.018
response to inorganic substanceGO:0010035960.018
protein oxidationGO:001815820.018
phenol containing compound metabolic processGO:0018958600.018
neuron apoptotic processGO:00514021420.017
ion transmembrane transportGO:00342203610.017
cd4 positive alpha beta t cell activationGO:0035710450.017
regulation of cellular catabolic processGO:00313292420.017
regulation of defense responseGO:00313472330.017
organic hydroxy compound metabolic processGO:19016152030.017
protein modification by small protein conjugationGO:00324461870.017
protein ubiquitinationGO:00165671710.016
morphogenesis of a branching epitheliumGO:00611381930.016
guanosine containing compound catabolic processGO:19010691440.016
mitochondrial transportGO:0006839360.016
nucleotide biosynthetic processGO:0009165780.016
epithelial tube morphogenesisGO:00605623030.016
energy derivation by oxidation of organic compoundsGO:0015980770.015
regulation of transmembrane transportGO:00347621280.015
small gtpase mediated signal transductionGO:0007264970.015
regulation of endopeptidase activityGO:0052548890.015
protein catabolic processGO:00301632210.015
regulation of response to woundingGO:19030341890.015
regulation of androgen receptor signaling pathwayGO:006076530.015
monocarboxylic acid metabolic processGO:00327871910.015
nitrogen compound transportGO:00717052710.015
regulation of t cell activationGO:00508631700.014
regulation of protein ubiquitinationGO:0031396520.014
membrane depolarizationGO:0051899640.014
ras protein signal transductionGO:0007265770.014
negative regulation of hydrolase activityGO:0051346710.014
dopamine uptake involved in synaptic transmissionGO:005158340.014
receptor mediated endocytosisGO:0006898510.014
negative regulation of molecular functionGO:00440922580.014
positive regulation of gtp catabolic processGO:0033126850.014
ventricular cardiac muscle tissue developmentGO:0003229380.014
positive regulation of apoptotic signaling pathwayGO:2001235950.014
leukocyte proliferationGO:00706611720.014
cellular modified amino acid metabolic processGO:0006575630.014
heart morphogenesisGO:00030071780.013
cell proliferation in hindbrainGO:0021534100.013
response to organic cyclic compoundGO:00140701980.013
divalent metal ion transportGO:00708381720.013
modification dependent macromolecule catabolic processGO:00436321330.013
lymphocyte proliferationGO:00466511640.013
purine nucleoside biosynthetic processGO:0042451190.013
immune effector processGO:00022523210.013
alcohol metabolic processGO:00060661160.013
regulation of generation of precursor metabolites and energyGO:0043467380.013
Worm
calcium ion transportGO:00068161590.013
negative regulation of phosphate metabolic processGO:00459361840.013
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.013
catecholamine uptake involved in synaptic transmissionGO:005193440.013
regulation of cell activationGO:00508652890.013
negative regulation of mammary gland epithelial cell proliferationGO:003360030.012
cardiac chamber developmentGO:00032051080.012
cellular protein catabolic processGO:00442571550.012
carboxylic acid catabolic processGO:0046395510.012
purine containing compound catabolic processGO:00725232130.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.012
protein modification by small protein conjugation or removalGO:00706472070.012
organelle assemblyGO:00709251770.012
rho protein signal transductionGO:0007266320.012
cellular macromolecule catabolic processGO:00442652060.012
membrane fusionGO:0061025380.012
regulation of protein kinase activityGO:00458592320.012
regulation of gtp catabolic processGO:00331241130.012
regulation of neurotransmitter levelsGO:0001505870.012
positive regulation of transferase activityGO:00513471670.012
cell type specific apoptotic processGO:00972852680.012
action potentialGO:0001508780.012
regulation of mitochondrial membrane potentialGO:0051881170.012
negative regulation of peptidase activityGO:0010466460.012
positive regulation of interleukin 8 productionGO:003275720.012
response to iron ionGO:001003940.012
response to reactive oxygen speciesGO:0000302560.012
positive regulation of cytokine productionGO:00018191740.011
regulation of protein modification by small protein conjugation or removalGO:1903320570.011
regulation of homeostatic processGO:00328441820.011
cellular response to topologically incorrect proteinGO:0035967250.011
hydrogen peroxide metabolic processGO:0042743160.011
regulation of interleukin 8 productionGO:003267730.011
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143180.011
regulation of protein maturationGO:1903317960.011
feeding behaviorGO:0007631620.011
Worm
negative regulation of neuron deathGO:1901215980.011
regulation of leukocyte proliferationGO:00706631210.011
regulation of protein processingGO:0070613960.011
respiratory tube developmentGO:00303231670.011
hormone metabolic processGO:0042445860.011
positive regulation of protein homodimerization activityGO:009007310.011
regulation of phospholipase c activityGO:190027430.011
striated muscle tissue developmentGO:00147062930.011
negative regulation of protein maturationGO:1903318790.011
striated muscle cell developmentGO:00550021250.011
response to decreased oxygen levelsGO:0036293590.011
Fly
hatchingGO:003518840.011
neurotransmitter transportGO:0006836760.010
multicellular organism growthGO:00352641610.010
Worm
negative regulation of cellular protein metabolic processGO:00322692470.010
divalent inorganic cation transportGO:00725111780.010
leukocyte mediated immunityGO:00024431740.010
apoptotic mitochondrial changesGO:0008637480.010
regulation of establishment of protein localizationGO:00702011810.010
adult locomotory behaviorGO:0008344910.010
cell proliferation in external granule layerGO:0021924100.010
morphogenesis of a branching structureGO:00017632030.010

Phb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.041
disease of anatomical entityDOID:700.041
central nervous system diseaseDOID:33100.041
disease of metabolismDOID:001466700.038
inherited metabolic disorderDOID:65500.010