| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.991 | Yeast |
| proteasomal ubiquitin independent protein catabolic process | GO:0010499 | 1 | 0.988 | Yeast |
| cellular protein catabolic process | GO:0044257 | 155 | 0.973 | Yeast |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.967 | Yeast |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.947 | Yeast |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.887 | Yeast |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.844 | Yeast |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.842 | Yeast |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.826 | Yeast |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.771 | |
| protein catabolic process | GO:0030163 | 221 | 0.702 | Yeast |
| macromolecule catabolic process | GO:0009057 | 281 | 0.646 | Yeast |
| multicellular organismal aging | GO:0010259 | 24 | 0.611 | Worm |
| proteasome assembly | GO:0043248 | 1 | 0.508 | |
| male gamete generation | GO:0048232 | 285 | 0.369 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.286 | |
| spermatid differentiation | GO:0048515 | 115 | 0.194 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.163 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.157 | |
| determination of adult lifespan | GO:0008340 | 11 | 0.152 | Worm |
| mitotic cell cycle | GO:0000278 | 195 | 0.135 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 2 | 0.134 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.121 | |
| spermatid development | GO:0007286 | 108 | 0.121 | |
| oocyte construction | GO:0007308 | 2 | 0.110 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.104 | |
| mitochondrial transport | GO:0006839 | 36 | 0.101 | |
| microtubule based process | GO:0007017 | 236 | 0.098 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.089 | |
| organelle fission | GO:0048285 | 170 | 0.083 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.078 | |
| spermatogenesis | GO:0007283 | 284 | 0.076 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.075 | |
| oocyte axis specification | GO:0007309 | 2 | 0.073 | |
| germ cell development | GO:0007281 | 185 | 0.071 | |
| pole plasm assembly | GO:0007315 | 2 | 0.069 | |
| axonogenesis | GO:0007409 | 274 | 0.068 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.064 | |
| dna metabolic process | GO:0006259 | 303 | 0.062 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.062 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.060 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.057 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.056 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.055 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.054 | |
| mitochondrion organization | GO:0007005 | 134 | 0.053 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.052 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.051 | |
| spindle organization | GO:0007051 | 28 | 0.048 | |
| organelle assembly | GO:0070925 | 177 | 0.048 | |
| transmembrane transport | GO:0055085 | 412 | 0.047 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.046 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.045 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.044 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.041 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.040 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.040 | |
| amine metabolic process | GO:0009308 | 45 | 0.038 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.038 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.038 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.037 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.035 | |
| gonad development | GO:0008406 | 141 | 0.035 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 31 | 0.035 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.034 | |
| inflammatory response | GO:0006954 | 244 | 0.034 | |
| protein secretion | GO:0009306 | 111 | 0.033 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.032 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.032 | |
| protein targeting | GO:0006605 | 143 | 0.031 | |
| protein import | GO:0017038 | 101 | 0.031 | |
| chromatin modification | GO:0016568 | 187 | 0.031 | |
| dephosphorylation | GO:0016311 | 129 | 0.030 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.030 | |
| response to temperature stimulus | GO:0009266 | 55 | 0.029 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.029 | |
| endocytosis | GO:0006897 | 168 | 0.029 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.029 | |
| forebrain development | GO:0030900 | 302 | 0.028 | |
| protein localization to mitochondrion | GO:0070585 | 15 | 0.028 | |
| response to oxidative stress | GO:0006979 | 123 | 0.028 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.028 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.028 | |
| protein refolding | GO:0042026 | 1 | 0.027 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.027 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.027 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.027 | |
| maintenance of location | GO:0051235 | 89 | 0.026 | |
| alcohol metabolic process | GO:0006066 | 116 | 0.026 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.026 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.025 | |
| cell maturation | GO:0048469 | 127 | 0.025 | |
| membrane organization | GO:0061024 | 245 | 0.025 | |
| protein maturation | GO:0051604 | 176 | 0.024 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.024 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.024 | |
| protein localization to membrane | GO:0072657 | 108 | 0.024 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.024 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.023 | |
| regulation of binding | GO:0051098 | 111 | 0.023 | |
| translation | GO:0006412 | 93 | 0.023 | |
| endomembrane system organization | GO:0010256 | 147 | 0.023 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.023 | |
| oogenesis | GO:0048477 | 56 | 0.023 | |
| camera type eye development | GO:0043010 | 266 | 0.022 | |
| response to peptide | GO:1901652 | 136 | 0.022 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.022 | |
| regionalization | GO:0003002 | 337 | 0.022 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.022 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.021 | |
| stem cell differentiation | GO:0048863 | 268 | 0.021 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.021 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.021 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.021 | |
| body morphogenesis | GO:0010171 | 45 | 0.020 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.020 | |
| protein processing | GO:0016485 | 163 | 0.020 | |
| female gamete generation | GO:0007292 | 74 | 0.020 | |
| intracellular protein transport | GO:0006886 | 204 | 0.019 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.019 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.019 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.019 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.019 | |
| mrna processing | GO:0006397 | 63 | 0.019 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.019 | |
| mapk cascade | GO:0000165 | 281 | 0.019 | |
| regulation of histone h3 k4 methylation | GO:0051569 | 12 | 0.019 | |
| cell division | GO:0051301 | 120 | 0.018 | |
| developmental maturation | GO:0021700 | 193 | 0.018 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.018 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.018 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.018 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.018 | |
| telencephalon development | GO:0021537 | 186 | 0.018 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.018 | |
| synaptic transmission | GO:0007268 | 329 | 0.018 | |
| stem cell development | GO:0048864 | 219 | 0.018 | |
| protein localization to organelle | GO:0033365 | 185 | 0.018 | |
| regulation of translation | GO:0006417 | 71 | 0.018 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.018 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.017 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.017 | |
| double strand break repair | GO:0006302 | 48 | 0.017 | |
| fertilization | GO:0009566 | 127 | 0.017 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.017 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.017 | |
| cellular response to lipid | GO:0071396 | 145 | 0.017 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.017 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.017 | |
| dna repair | GO:0006281 | 107 | 0.016 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.016 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.016 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.016 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.016 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 4 | 0.016 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.016 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.016 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.016 | |
| glucose homeostasis | GO:0042593 | 128 | 0.016 | |
| mitotic spindle organization | GO:0007052 | 10 | 0.015 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.015 | |
| establishment or maintenance of microtubule cytoskeleton polarity | GO:0030951 | 1 | 0.015 | |
| protein homotrimerization | GO:0070207 | 4 | 0.015 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.015 | |
| lipid localization | GO:0010876 | 126 | 0.015 | |
| nuclear import | GO:0051170 | 95 | 0.015 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.015 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.015 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.015 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.014 | |
| positive regulation of growth | GO:0045927 | 104 | 0.014 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.014 | |
| nucleobase containing compound transport | GO:0015931 | 27 | 0.014 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.014 | |
| extracellular structure organization | GO:0043062 | 148 | 0.014 | |
| regulation of reproductive process | GO:2000241 | 66 | 0.014 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.014 | |
| t cell activation | GO:0042110 | 289 | 0.014 | |
| dendrite development | GO:0016358 | 115 | 0.014 | |
| double strand break repair via nonhomologous end joining | GO:0006303 | 10 | 0.014 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.014 | |
| compound eye development | GO:0048749 | 1 | 0.014 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.014 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.014 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.014 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.014 | |
| single organism nuclear import | GO:1902593 | 95 | 0.014 | |
| response to alcohol | GO:0097305 | 48 | 0.013 | |
| non recombinational repair | GO:0000726 | 10 | 0.013 | |
| nuclear division | GO:0000280 | 158 | 0.013 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.013 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.013 | |
| epithelial to mesenchymal transition | GO:0001837 | 47 | 0.013 | |
| spindle assembly involved in mitosis | GO:0090307 | 4 | 0.013 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.013 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.013 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.013 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.013 | |
| protein deubiquitination | GO:0016579 | 19 | 0.013 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.013 | |
| mirna catabolic process | GO:0010587 | 2 | 0.013 | |
| zymogen activation | GO:0031638 | 41 | 0.012 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.012 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.012 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.012 | |
| sperm individualization | GO:0007291 | 1 | 0.012 | |
| single fertilization | GO:0007338 | 82 | 0.012 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.012 | |
| oocyte differentiation | GO:0009994 | 35 | 0.012 | |
| glycerolipid biosynthetic process | GO:0045017 | 50 | 0.012 | |
| cation transport | GO:0006812 | 399 | 0.012 | |
| molting cycle | GO:0042303 | 90 | 0.012 | Worm |
| regulation of jnk cascade | GO:0046328 | 62 | 0.012 | |
| segmentation | GO:0035282 | 93 | 0.012 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.012 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.012 | |
| protein localization to chromatin | GO:0071168 | 3 | 0.011 | |
| adult locomotory behavior | GO:0008344 | 91 | 0.011 | |
| response to peptide hormone | GO:0043434 | 127 | 0.011 | |
| nucleus organization | GO:0006997 | 45 | 0.011 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.011 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.011 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.011 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.011 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.011 | |
| nuclear transport | GO:0051169 | 139 | 0.011 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.011 | |
| rna processing | GO:0006396 | 105 | 0.011 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 10 | 0.011 | |
| exocytosis | GO:0006887 | 121 | 0.011 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.011 | |
| regulation of exit from mitosis | GO:0007096 | 1 | 0.011 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.011 | |
| stem cell maintenance | GO:0019827 | 130 | 0.011 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.011 | |
| ribosomal large subunit assembly | GO:0000027 | 2 | 0.011 | |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 5 | 0.011 | |
| sensory perception | GO:0007600 | 245 | 0.011 | |
| maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna | GO:0000463 | 1 | 0.011 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.011 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 2 | 0.010 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.010 | |
| organelle disassembly | GO:1903008 | 2 | 0.010 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.010 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.010 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.010 | |