| proteasomal ubiquitin independent protein catabolic process | GO:0010499 | 1 | 0.998 | Yeast |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.988 | Yeast |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.943 | Yeast |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.935 | Yeast |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.924 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.921 | Yeast |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.920 | Yeast |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.905 | Yeast |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.886 | Yeast |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.851 | Yeast |
| protein catabolic process | GO:0030163 | 221 | 0.798 | Yeast |
| proteasome assembly | GO:0043248 | 1 | 0.662 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.587 | Yeast |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.310 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.307 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.224 | |
| dna metabolic process | GO:0006259 | 303 | 0.210 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.187 | |
| protein import | GO:0017038 | 101 | 0.153 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.144 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.132 | |
| amine metabolic process | GO:0009308 | 45 | 0.114 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.106 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.104 | |
| protein localization to organelle | GO:0033365 | 185 | 0.102 | |
| male gamete generation | GO:0048232 | 285 | 0.101 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.095 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.093 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.085 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.081 | |
| protein import into nucleus | GO:0006606 | 95 | 0.079 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.079 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.074 | |
| extracellular structure organization | GO:0043062 | 148 | 0.073 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.073 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.071 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 4 | 0.071 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.069 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.067 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.065 | |
| negative regulation of defense response | GO:0031348 | 77 | 0.062 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.060 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.058 | |
| recombinational repair | GO:0000725 | 21 | 0.056 | |
| spindle assembly involved in mitosis | GO:0090307 | 4 | 0.056 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.053 | |
| t cell activation | GO:0042110 | 289 | 0.053 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.052 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.052 | |
| nuclear import | GO:0051170 | 95 | 0.051 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.050 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.049 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.049 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.048 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.047 | |
| gonad development | GO:0008406 | 141 | 0.047 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.046 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.045 | |
| single organism nuclear import | GO:1902593 | 95 | 0.045 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.044 | |
| intracellular protein transport | GO:0006886 | 204 | 0.044 | |
| protein maturation | GO:0051604 | 176 | 0.044 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.044 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.043 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.041 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.041 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.040 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.040 | |
| molting cycle | GO:0042303 | 90 | 0.039 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.039 | |
| cellular response to lipid | GO:0071396 | 145 | 0.038 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.037 | |
| cellular homeostasis | GO:0019725 | 240 | 0.036 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.035 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.035 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.035 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.035 | |
| nuclear transport | GO:0051169 | 139 | 0.034 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.034 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.034 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.034 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.034 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.034 | |
| mapk cascade | GO:0000165 | 281 | 0.033 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.033 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.033 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.032 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.032 | |
| regulation of inflammatory response to antigenic stimulus | GO:0002861 | 21 | 0.032 | |
| protein targeting | GO:0006605 | 143 | 0.032 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.031 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.030 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 31 | 0.030 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.030 | |
| blood coagulation | GO:0007596 | 76 | 0.029 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.029 | |
| 4 hydroxyproline metabolic process | GO:0019471 | 5 | 0.029 | |
| mrna metabolic process | GO:0016071 | 84 | 0.029 | |
| regulation of defense response | GO:0031347 | 233 | 0.028 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.028 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.028 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.028 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.027 | |
| t cell proliferation | GO:0042098 | 120 | 0.027 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.027 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.027 | |
| negative regulation of inflammatory response to antigenic stimulus | GO:0002862 | 10 | 0.026 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.026 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 4 | 0.026 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.026 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.026 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.026 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.026 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.026 | |
| respiratory burst | GO:0045730 | 8 | 0.026 | |
| synaptic transmission | GO:0007268 | 329 | 0.025 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.025 | |
| membrane organization | GO:0061024 | 245 | 0.025 | |
| spermatogenesis | GO:0007283 | 284 | 0.025 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.024 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.024 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.024 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.024 | |
| inflammatory response to antigenic stimulus | GO:0002437 | 30 | 0.024 | |
| oocyte construction | GO:0007308 | 2 | 0.024 | |
| negative regulation of inflammatory response | GO:0050728 | 61 | 0.024 | |
| spindle organization | GO:0007051 | 28 | 0.023 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 59 | 0.023 | |
| gland development | GO:0048732 | 330 | 0.023 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.023 | |
| organelle fission | GO:0048285 | 170 | 0.023 | |
| chromatin modification | GO:0016568 | 187 | 0.023 | |
| regulation of cell activation | GO:0050865 | 289 | 0.023 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.023 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.022 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.022 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.022 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.022 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.022 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.022 | |
| regulation of protein localization | GO:0032880 | 231 | 0.021 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.021 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.021 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.021 | |
| protein oligomerization | GO:0051259 | 67 | 0.021 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.021 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.021 | |
| dna dealkylation | GO:0035510 | 11 | 0.021 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.020 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.020 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.020 | |
| coagulation | GO:0050817 | 78 | 0.020 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.020 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.020 | |
| inflammatory response | GO:0006954 | 244 | 0.019 | |
| male germ cell proliferation | GO:0002176 | 6 | 0.019 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.019 | |
| cellular response to glucose stimulus | GO:0071333 | 45 | 0.019 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.019 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.019 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.019 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.019 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.019 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.019 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.019 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.018 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.018 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.018 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.018 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.018 | |
| protein complex localization | GO:0031503 | 19 | 0.017 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.017 | |
| response to hydroperoxide | GO:0033194 | 6 | 0.017 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.017 | |
| response to acid chemical | GO:0001101 | 111 | 0.017 | |
| organelle assembly | GO:0070925 | 177 | 0.017 | |
| stem cell differentiation | GO:0048863 | 268 | 0.017 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.017 | |
| negative regulation of leukocyte differentiation | GO:1902106 | 51 | 0.017 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.016 | |
| cation transport | GO:0006812 | 399 | 0.016 | |
| protein polymerization | GO:0051258 | 57 | 0.016 | |
| regulation of ion transport | GO:0043269 | 215 | 0.016 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.016 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.016 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.016 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.016 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.016 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.016 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.016 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.016 | |
| response to oxidative stress | GO:0006979 | 123 | 0.016 | |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001239 | 26 | 0.016 | |
| transmembrane transport | GO:0055085 | 412 | 0.015 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.015 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.015 | |
| transcription factor import into nucleus | GO:0042991 | 26 | 0.015 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.015 | |
| regulation of protein transport | GO:0051223 | 163 | 0.015 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.015 | |
| dna catabolic process endonucleolytic | GO:0000737 | 15 | 0.015 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 55 | 0.015 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.015 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.015 | |
| leukocyte mediated cytotoxicity | GO:0001909 | 62 | 0.015 | |
| hydrogen peroxide metabolic process | GO:0042743 | 16 | 0.015 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.015 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.014 | |
| negative regulation of lipopolysaccharide mediated signaling pathway | GO:0031665 | 3 | 0.014 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.014 | |
| neural tube formation | GO:0001841 | 108 | 0.014 | |
| production of molecular mediator involved in inflammatory response | GO:0002532 | 21 | 0.014 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.014 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.014 | |
| response to inorganic substance | GO:0010035 | 96 | 0.014 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.014 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.014 | |
| response to hydrogen peroxide | GO:0042542 | 32 | 0.014 | |
| fertilization | GO:0009566 | 127 | 0.014 | |
| amide transport | GO:0042886 | 138 | 0.014 | |
| body morphogenesis | GO:0010171 | 45 | 0.013 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.013 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.013 | |
| cell redox homeostasis | GO:0045454 | 6 | 0.013 | |
| dna repair | GO:0006281 | 107 | 0.013 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.013 | |
| anion transport | GO:0006820 | 177 | 0.013 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.013 | |
| endomembrane system organization | GO:0010256 | 147 | 0.013 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.013 | |
| double strand break repair via homologous recombination | GO:0000724 | 21 | 0.013 | |
| activation of mapk activity | GO:0000187 | 59 | 0.013 | |
| dna recombination | GO:0006310 | 92 | 0.013 | |
| heart contraction | GO:0060047 | 93 | 0.013 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 57 | 0.013 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.013 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.012 | |
| lateral inhibition | GO:0046331 | 1 | 0.012 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.012 | |
| regulation of phosphatidylcholine biosynthetic process | GO:2001245 | 2 | 0.012 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.012 | |
| camera type eye development | GO:0043010 | 266 | 0.012 | |
| positive regulation of hemostasis | GO:1900048 | 10 | 0.012 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.012 | |
| glucose homeostasis | GO:0042593 | 128 | 0.012 | |
| regulation of blood coagulation | GO:0030193 | 28 | 0.012 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.012 | |
| positive regulation of coagulation | GO:0050820 | 13 | 0.012 | |
| cell killing | GO:0001906 | 67 | 0.012 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.012 | |
| thymus development | GO:0048538 | 41 | 0.012 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.012 | |
| microtubule based process | GO:0007017 | 236 | 0.012 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.012 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.012 | |
| placenta development | GO:0001890 | 140 | 0.012 | |
| peptide transport | GO:0015833 | 133 | 0.011 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.011 | |
| spindle assembly | GO:0051225 | 13 | 0.011 | |
| protein processing | GO:0016485 | 163 | 0.011 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.011 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.011 | |
| negative regulation of signal transduction in absence of ligand | GO:1901099 | 16 | 0.011 | |
| removal of superoxide radicals | GO:0019430 | 12 | 0.011 | |
| development of primary male sexual characteristics | GO:0046546 | 88 | 0.011 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.011 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.011 | |
| response to alcohol | GO:0097305 | 48 | 0.011 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.011 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 45 | 0.011 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.011 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.011 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 58 | 0.011 | |
| negative regulation of cellular catabolic process | GO:0031330 | 47 | 0.011 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.011 | |
| positive regulation of growth | GO:0045927 | 104 | 0.011 | |
| cellular response to oxygen radical | GO:0071450 | 14 | 0.011 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.011 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.011 | |
| positive regulation of ion transport | GO:0043270 | 65 | 0.011 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.011 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.011 | |
| cytokinetic process | GO:0032506 | 2 | 0.011 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.011 | |
| rhythmic process | GO:0048511 | 174 | 0.011 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.010 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.010 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.010 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.010 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.010 | |
| negative regulation of reactive oxygen species metabolic process | GO:2000378 | 10 | 0.010 | |
| protein methylation | GO:0006479 | 81 | 0.010 | |
| t cell differentiation | GO:0030217 | 174 | 0.010 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.010 | |
