Mus musculus

0 known processes

Metap2

methionine aminopeptidase 2

(Aliases: AL024412,A930035J23Rik,p67,MGC102452,AU014659,Amp2,4930584B20Rik,AI047573,Mnpep,p67eIF2)

Metap2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
translationGO:0006412930.478
aromatic compound catabolic processGO:00194392860.142
male gamete generationGO:00482322850.130
cellular macromolecule catabolic processGO:00442652060.127
organic cyclic compound catabolic processGO:19013612950.116
rna processingGO:00063961050.114
cellular response to dna damage stimulusGO:00069742070.112
mitotic cell cycle processGO:19030471590.101
apoptotic signaling pathwayGO:00971903060.100
macromolecule catabolic processGO:00090572810.098
nucleobase containing small molecule metabolic processGO:00550863520.092
mrna metabolic processGO:0016071840.086
cytoplasmic transportGO:00164822340.083
rna splicingGO:0008380540.082
ribose phosphate metabolic processGO:00196932910.078
cellular nitrogen compound catabolic processGO:00442702800.078
organelle fissionGO:00482851700.077
cellular amino acid metabolic processGO:00065201030.076
purine ribonucleoside triphosphate metabolic processGO:00092052200.076
purine ribonucleoside triphosphate catabolic processGO:00092071990.069
heterocycle catabolic processGO:00467002800.068
purine ribonucleotide catabolic processGO:00091542080.067
nucleotide catabolic processGO:00091662170.067
ribonucleoside triphosphate catabolic processGO:00092031990.066
purine ribonucleotide metabolic processGO:00091502900.064
ribonucleoside catabolic processGO:00424542060.063
purine nucleoside triphosphate catabolic processGO:00091462030.063
mitotic cell cycleGO:00002781950.062
dna metabolic processGO:00062593030.061
spermatogenesisGO:00072832840.060
positive regulation of apoptotic processGO:00430652170.060
regulation of apoptotic signaling pathwayGO:20012331970.060
organonitrogen compound catabolic processGO:19015652640.058
chromatin modificationGO:00165681870.058
nucleoside catabolic processGO:00091642060.056
purine containing compound metabolic processGO:00725213110.056
germ cell developmentGO:00072811850.056
purine containing compound catabolic processGO:00725232130.054
ribonucleotide catabolic processGO:00092612080.053
nucleoside phosphate catabolic processGO:19012922220.053
ribonucleoside metabolic processGO:00091192450.052
purine nucleoside metabolic processGO:00422782410.051
nucleoside triphosphate metabolic processGO:00091412300.051
purine nucleotide metabolic processGO:00061633020.051
purine nucleoside catabolic processGO:00061522050.050
atp metabolic processGO:0046034750.050
nucleoside metabolic processGO:00091162460.050
atp catabolic processGO:0006200550.050
purine ribonucleoside metabolic processGO:00461282410.048
purine nucleoside triphosphate metabolic processGO:00091442260.048
microtubule based processGO:00070172360.048
cellular amine metabolic processGO:0044106440.048
nucleoside triphosphate catabolic processGO:00091432050.047
ribonucleotide metabolic processGO:00092592910.047
chromatin organizationGO:00063252060.047
microtubule cytoskeleton organizationGO:00002261570.046
amine metabolic processGO:0009308450.046
positive regulation of cell deathGO:00109422240.045
glycosyl compound metabolic processGO:19016572460.045
nucleic acid phosphodiester bond hydrolysisGO:0090305490.044
organelle assemblyGO:00709251770.043
nitrogen compound transportGO:00717052710.042
nucleotide metabolic processGO:00091173320.041
posttranscriptional regulation of gene expressionGO:00106081550.041
ras protein signal transductionGO:0007265770.039
purine ribonucleoside catabolic processGO:00461302050.039
positive regulation of apoptotic signaling pathwayGO:2001235950.038
histone modificationGO:00165701590.038
ribonucleoside monophosphate metabolic processGO:0009161800.037
dna repairGO:00062811070.036
regulation of cellular response to stressGO:00801351590.036
ribonucleoside triphosphate metabolic processGO:00091992200.036
mitotic nuclear divisionGO:0007067480.036
regulation of cellular component biogenesisGO:00440871810.036
positive regulation of programmed cell deathGO:00430682180.035
purine nucleotide catabolic processGO:00061952110.035
dna conformation changeGO:0071103370.035
purine nucleoside monophosphate catabolic processGO:0009128580.034
nucleoside monophosphate metabolic processGO:0009123850.034
negative regulation of intracellular signal transductionGO:19025321670.034
nuclear transportGO:00511691390.033
developmental maturationGO:00217001930.033
carbohydrate derivative catabolic processGO:19011362310.033
regulation of cell motilityGO:20001452360.032
response to organic cyclic compoundGO:00140701980.032
cellular ketone metabolic processGO:0042180840.032
regulation of translationGO:0006417710.031
gene silencingGO:0016458380.031
glycosyl compound catabolic processGO:19016582060.031
nucleocytoplasmic transportGO:00069131390.030
response to organonitrogen compoundGO:00102432460.030
positive regulation of cellular component biogenesisGO:0044089940.030
nucleoside phosphate metabolic processGO:00067533380.029
organophosphate catabolic processGO:00464342320.029
negative regulation of cellular component organizationGO:00511291940.028
negative regulation of cell proliferationGO:00082852960.028
positive regulation of cellular amine metabolic processGO:003324050.028
protein catabolic processGO:00301632210.028
nuclear divisionGO:00002801580.028
negative regulation of protein metabolic processGO:00512482820.027
regulation of protein localizationGO:00328802310.027
endocytosisGO:00068971680.027
Worm
gene silencing by rnaGO:0031047190.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
regulation of organelle organizationGO:00330432890.025
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.025
rna transportGO:0050658180.025
regulation of cellular amino acid metabolic processGO:000652150.025
single organism nuclear importGO:1902593950.025
negative regulation of molecular functionGO:00440922580.025
protein processingGO:00164851630.025
Human
response to growth factorGO:00708481980.025
purine ribonucleoside monophosphate catabolic processGO:0009169570.024
regulation of protein catabolic processGO:00421761080.024
intracellular protein transportGO:00068862040.024
lateral inhibitionGO:004633110.023
regulation of cell migrationGO:00303342190.023
spermatid differentiationGO:00485151150.023
spermatid developmentGO:00072861080.023
mitotic sister chromatid segregationGO:0000070140.023
locomotory behaviorGO:00076261950.023
protein targetingGO:00066051430.023
response to oxidative stressGO:00069791230.022
striated muscle tissue developmentGO:00147062930.022
adult behaviorGO:00305341350.022
rna interferenceGO:001624620.022
regulation of cell cycleGO:00517262810.022
stem cell developmentGO:00488642190.022
cell maturationGO:00484691270.022
purine nucleoside monophosphate metabolic processGO:0009126810.022
regulation of cellular catabolic processGO:00313292420.022
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.021
mrna splicing via spliceosomeGO:0000398430.021
negative regulation of cellular protein metabolic processGO:00322692470.021
cell growthGO:00160491300.021
maternal determination of anterior posterior axis embryoGO:000835820.021
purine ribonucleoside monophosphate metabolic processGO:0009167800.021
ribonucleoside monophosphate catabolic processGO:0009158570.021
development of primary sexual characteristicsGO:00451371430.020
Worm
nuclear importGO:0051170950.020
multi multicellular organism processGO:00447061090.020
skeletal muscle organ developmentGO:00605381630.020
regulation of bindingGO:00510981110.020
intrinsic apoptotic signaling pathwayGO:00971931320.020
placenta developmentGO:00018901400.020
regulation of mitotic cell cycleGO:00073461260.020
regulation of intracellular transportGO:00323861590.020
pole plasm assemblyGO:000731520.020
oocyte anterior posterior axis specificationGO:000731420.019
regulation of cellular amine metabolic processGO:0033238200.019
chromosome segregationGO:0007059480.019
regulation of intracellular protein transportGO:0033157820.019
regionalizationGO:00030023370.019
muscle tissue developmentGO:00605373080.019
cellular response to lipidGO:00713961450.019
positive regulation of cell developmentGO:00107202370.018
positive regulation of cell cycleGO:0045787920.018
response to dsrnaGO:0043331300.018
cellular response to organonitrogen compoundGO:00714171450.018
response to inorganic substanceGO:0010035960.018
muscle cell differentiationGO:00426922610.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
regulation of mitotic cell cycle phase transitionGO:1901990730.018
multicellular organism growthGO:00352641610.018
negative regulation of cell cycleGO:00457861230.017
establishment of protein localization to organelleGO:00725941180.017
ribonucleoprotein complex subunit organizationGO:0071826280.017
fertilizationGO:00095661270.017
trna metabolic processGO:0006399110.017
cellular protein complex assemblyGO:00436231160.017
transmembrane transportGO:00550854120.017
regulation of proteolysisGO:00301621640.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
cell type specific apoptotic processGO:00972852680.017
positive regulation of nervous system developmentGO:00519622210.017
oogenesisGO:0048477560.017
ossificationGO:00015032160.017
ribosomal small subunit biogenesisGO:004227440.017
rna splicing via transesterification reactionsGO:0000375430.017
regulation of hydrolase activityGO:00513362460.017
mesenchyme developmentGO:00604851520.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
protein importGO:00170381010.016
epithelial cell proliferationGO:00506731740.016
mesenchymal cell developmentGO:0014031930.016
negative regulation of phosphate metabolic processGO:00459361840.016
rna localizationGO:0006403230.016
mapk cascadeGO:00001652810.016
stem cell differentiationGO:00488632680.016
negative regulation of cell developmentGO:00107211690.016
mesenchymal cell differentiationGO:00487621070.016
regulation of cytoplasmic transportGO:19036491120.016
nucleoside monophosphate catabolic processGO:0009125590.015
establishment or maintenance of cytoskeleton polarityGO:003095220.015
inflammatory responseGO:00069542440.015
positive regulation of protein modification processGO:00314012990.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
meiotic cell cycleGO:00513211220.015
lipid localizationGO:00108761260.015
oocyte axis specificationGO:000730920.015
positive regulation of cellular catabolic processGO:00313311480.015
anatomical structure homeostasisGO:00602491450.014
synaptic transmissionGO:00072683290.014
negative regulation of immune system processGO:00026832090.014
regulation of cell cycle processGO:00105641600.014
protein localization to nucleusGO:00345041210.014
maintenance of locationGO:0051235890.014
regulation of protein processingGO:0070613960.014
cellular homeostasisGO:00197252400.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
male sex differentiationGO:00466611090.014
protein localization to organelleGO:00333651850.014
positive regulation of intracellular protein transportGO:0090316420.013
protein import into nucleusGO:0006606950.013
cellular response to cytokine stimulusGO:00713451890.013
response to acid chemicalGO:00011011110.013
spindle assembly involved in mitosisGO:009030740.013
action potentialGO:0001508780.013
positive regulation of protein phosphorylationGO:00019342420.013
cellular response to inorganic substanceGO:0071241370.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.013
ubiquitin dependent protein catabolic processGO:00065111290.013
small gtpase mediated signal transductionGO:0007264970.013
regulation of protein maturationGO:1903317960.013
g1 s transition of mitotic cell cycleGO:0000082570.013
oocyte developmentGO:0048599330.013
olfactory learningGO:000835520.012
axonogenesisGO:00074092740.012
development of primary male sexual characteristicsGO:0046546880.012
female gamete generationGO:0007292740.012
cell cycle g1 s phase transitionGO:0044843570.012
cell adhesionGO:00071553290.012
adult locomotory behaviorGO:0008344910.012
double strand break repairGO:0006302480.012
organelle localizationGO:00516401790.012
regulation of cellular ketone metabolic processGO:0010565660.012
response to light stimulusGO:00094161350.012
regulation of establishment of protein localizationGO:00702011810.012
regulation of defense responseGO:00313472330.012
dna packagingGO:0006323300.012
genitalia developmentGO:0048806370.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.012
skeletal system developmentGO:00015013560.012
mitochondrion organizationGO:00070051340.011
histone acetylationGO:0016573410.011
response to radiationGO:00093141650.011
peptidyl amino acid modificationGO:00181933360.011
Human
membrane organizationGO:00610242450.011
positive regulation of dna templated transcription elongationGO:003278620.011
regulation of protein transportGO:00512231630.011
regulation of cell activationGO:00508652890.011
dna geometric changeGO:003239270.011
neuron deathGO:00709971540.011
regulation of chromatin modificationGO:1903308570.011
protein alkylationGO:0008213810.011
cellular response to growth factor stimulusGO:00713631970.011
gonad developmentGO:00084061410.011
Worm
small molecule biosynthetic processGO:00442831320.011
multicellular organismal homeostasisGO:00488711640.011
negative regulation of mitotic cell cycleGO:0045930580.011
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.011
cellular response to oxidative stressGO:0034599760.011
ribonucleoprotein complex disassemblyGO:003298830.011
actin cytoskeleton organizationGO:00300362200.011
protein methylationGO:0006479810.010
spliceosomal complex disassemblyGO:000039010.010
male gonad developmentGO:0008584880.010
regulation of system processGO:00440572000.010
regulation of response to woundingGO:19030341890.010
single fertilizationGO:0007338820.010
multicellular organismal signalingGO:0035637910.010
forebrain developmentGO:00309003020.010
negative regulation of proteolysisGO:0045861740.010
regulation of mapk cascadeGO:00434082480.010
protein modification by small protein removalGO:0070646210.010
connective tissue developmentGO:00614481790.010

Metap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
musculoskeletal system diseaseDOID:1700.016
central nervous system diseaseDOID:33100.014
neurodegenerative diseaseDOID:128900.010