Mus musculus

118 known processes

Tnfrsf1a

tumor necrosis factor receptor superfamily, member 1a

(Aliases: TNF-R,TNFalpha-R1,FPF,TNFAR,TNFR60,CD120a,TNF-R-I,TNFRI,Tnfr1,Tnfr-2,TNFRp55,TNF-R1,p55,TNF-alphaR1,TNF-R55,p55-R)

Tnfrsf1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide binding oligomerization domain containing signaling pathwayGO:007042361.000
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043161.000
i kappab kinase nf kappab signalingGO:0007249851.000
Human
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753101.000
antibacterial peptide productionGO:000277821.000
regulation of interleukin 6 productionGO:0032675551.000
Rat
necroptotic signaling pathwayGO:009752731.000
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601451.000
Mouse
defense response to other organismGO:00985421971.000
tumor necrosis factor mediated signaling pathwayGO:0033209130.999
cytokine mediated signaling pathwayGO:00192211150.999
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.999
response to interleukin 1GO:0070555110.999
cellular response to peptidoglycanGO:007122440.999
nik nf kappab signalingGO:0038061140.999
negative regulation of interleukin 10 secretionGO:200118020.999
regulation of cd8 positive alpha beta cytotoxic t cell extravasationGO:200045220.998
regulation of antibacterial peptide biosynthetic processGO:000280810.998
response to tumor necrosis factorGO:0034612260.998
cytokine biosynthetic processGO:0042089680.998
interferon beta biosynthetic processGO:004535040.998
regulation of cytokine production involved in immune responseGO:0002718260.997
production of molecular mediator of immune responseGO:00024401030.997
Mouse
antibacterial humoral responseGO:001973180.996
positive regulation of production of molecular mediator of immune responseGO:0002702450.996
positive regulation of defense responseGO:00313491240.996
positive regulation of antibacterial peptide biosynthetic processGO:000696310.995
lipopolysaccharide mediated signaling pathwayGO:0031663250.995
pattern recognition receptor signaling pathwayGO:0002221470.995
regulation of defense responseGO:00313472330.995
cellular response to molecule of bacterial originGO:0071219830.994
response to molecule of bacterial originGO:00022371430.994
Rat
negative regulation of interleukin 5 secretionGO:200066310.993
cellular response to interleukin 18GO:007135130.993
positive regulation of antimicrobial peptide productionGO:000222510.992
intrinsic apoptotic signaling pathwayGO:00971931320.992
positive regulation of immune effector processGO:00026991070.992
positive regulation of antimicrobial humoral responseGO:000276020.991
response to interleukin 15GO:007067230.991
positive regulation of leukocyte mediated immunityGO:0002705700.991
interleukin 5 secretionGO:007260320.991
necroptotic processGO:0070266210.991
Mouse
lymphocyte activation involved in immune responseGO:0002285930.991
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.990
defense response to gram positive bacteriumGO:0050830500.990
activation of immune responseGO:00022531380.990
positive regulation of protein phosphorylationGO:00019342420.990
Human
regulation of cytokine productionGO:00018172660.989
Rat
defense response to bacteriumGO:00427421190.989
positive regulation of response to woundingGO:1903036660.988
antimicrobial peptide productionGO:000277520.987
cellular response to lipopolysaccharideGO:0071222770.987
activation of innate immune responseGO:0002218560.987
cytokine productionGO:00018163190.986
Rat
cellular response to lipidGO:00713961450.986
Rat
programmed necrotic cell deathGO:0097300280.986
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510901060.984
regulation of cellular amino acid metabolic processGO:000652150.984
negative regulation of defense responseGO:0031348770.984
Human
antibacterial peptide biosynthetic processGO:000278020.982
immune response activating signal transductionGO:00027571160.982
adaptive immune responseGO:00022501550.982
Mouse
detection of molecule of bacterial originGO:003249020.981
ripoptosome assembly involved in necroptotic processGO:190102660.980
positive regulation of apoptotic signaling pathwayGO:2001235950.980
Mouse
i kappab phosphorylationGO:000725260.980
positive regulation of innate immune responseGO:0045089800.978
interleukin 18 mediated signaling pathwayGO:003565520.978
interleukin 13 secretionGO:007261120.977
t cell extravasationGO:007268340.976
cytokine production involved in immune responseGO:0002367340.976
negative regulation of interleukin 5 productionGO:003271440.976
regulation of tumor necrosis factor biosynthetic processGO:0042534100.975
positive regulation of protein modification processGO:00314012990.971
Human
myeloid leukocyte activationGO:0002274830.969
regulation of inflammatory responseGO:00507271470.967
interleukin 10 secretionGO:007260840.967
positive regulation of interleukin 12 productionGO:0032735210.966
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.964
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.964
negative regulation of inflammatory responseGO:0050728610.963
Human
cellular response to tumor necrosis factorGO:0071356210.963
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.962
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.962
response to lipopolysaccharideGO:00324961280.959
Rat
positive regulation of isotype switching to igg isotypesGO:004830470.959
regulation of defense response to bacteriumGO:190042430.957
immune effector processGO:00022523210.957
Mouse
regulation of cytokine biosynthetic processGO:0042035590.956
stress activated mapk cascadeGO:0051403800.955
response to molecule of fungal originGO:000223840.954
negative regulation of odontogenesis of dentin containing toothGO:004248910.953
immune response regulating cell surface receptor signaling pathwayGO:0002768800.952
fever generationGO:000166070.952
regulation of innate immune responseGO:0045088910.952
regulation of antibacterial peptide productionGO:000278610.951
growth involved in symbiotic interactionGO:0044110230.943
positive regulation of cytokine secretion involved in immune responseGO:000274120.941
regulation of acute inflammatory responseGO:0002673270.940
regulation of adaptive immune responseGO:0002819900.939
humoral immune responseGO:0006959570.939
positive regulation of interleukin 6 productionGO:0032755370.938
t helper cell lineage commitmentGO:000229560.935
innate immune response activating signal transductionGO:0002758500.935
regulation of necroptotic processGO:0060544100.932
alpha beta t cell proliferationGO:0046633210.931
immune response regulating signaling pathwayGO:00027641250.931
regulation of alpha beta t cell proliferationGO:0046640180.929
positive regulation of cytokine biosynthetic processGO:0042108400.929
positive regulation of adaptive immune responseGO:0002821610.929
interleukin 6 biosynthetic processGO:0042226120.928
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.927
activation of nf kappab inducing kinase activityGO:000725040.926
leukocyte apoptotic processGO:0071887710.925
Mouse
leukocyte activation involved in immune responseGO:00023661260.924
cellular response to lipoteichoic acidGO:007122360.923
positive regulation of lymphocyte proliferationGO:0050671700.921
toll like receptor signaling pathwayGO:0002224380.920
immunoglobulin mediated immune responseGO:0016064690.918
regulation of interleukin 5 secretionGO:200066220.916
natural killer cell degranulationGO:004332030.916
lymph node developmentGO:0048535180.914
regulation of growth of symbiont in hostGO:0044126190.913
cellular response to biotic stimulusGO:0071216920.911
defense response to gram negative bacteriumGO:0050829280.911
immunoglobulin secretionGO:0048305170.911
regulation of response to woundingGO:19030341890.911
positive regulation of cytokine productionGO:00018191740.908
Rat
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.907
positive regulation of interferon gamma productionGO:0032729390.906
negative regulation of reactive oxygen species biosynthetic processGO:190342700.905
type i interferon signaling pathwayGO:0060337100.903
somatic diversification of immune receptorsGO:0002200530.901
cellular response to interleukin 6GO:007135490.901
positive regulation of cytokine production involved in immune responseGO:0002720190.900
regulation of antimicrobial humoral responseGO:000275930.898
modulation of growth of symbiont involved in interaction with hostGO:0044144190.896
peptide biosynthetic processGO:0043043110.894
negative regulation of interleukin 13 productionGO:003269620.894
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.893
Rat
regulation of cytokine secretion involved in immune responseGO:000273940.893
glial cell apoptotic processGO:003434930.893
toll like receptor 4 signaling pathwayGO:003414290.893
regulation of interleukin 13 secretionGO:200066520.890
positive regulation of nf kappab transcription factor activityGO:0051092300.885
regulation of antimicrobial peptide productionGO:000278410.885
spleen developmentGO:0048536390.879
Mouse
positive regulation of b cell mediated immunityGO:0002714260.878
negative regulation of interleukin 13 secretionGO:200066610.875
positive regulation of stress activated mapk cascadeGO:0032874480.875
leukocyte migrationGO:00509001240.870
activation induced cell death of t cellsGO:0006924100.864
Mouse
b cell mediated immunityGO:0019724710.863
Mouse
positive regulation of organic acid transportGO:0032892110.857
cellular response to amino acid stimulusGO:0071230290.855
positive regulation of chemokine productionGO:0032722220.851
positive regulation of dna recombinationGO:0045911170.850
positive regulation of b cell proliferationGO:0030890240.846
response to peptidoglycanGO:003249490.844
regulation of interleukin 2 productionGO:0032663280.841
modulation by symbiont of defense related host nitric oxide productionGO:005216310.835
regulation of leukocyte proliferationGO:00706631210.834
amine metabolic processGO:0009308450.833
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.833
positive regulation of activation of membrane attack complexGO:000197020.826
cytokine secretion involved in immune responseGO:000237460.824
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.824
negative regulation of lymphocyte activationGO:0051250910.821
Mouse
peptidyl tyrosine phosphorylationGO:00181081430.818
Human
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.818
negative regulation of necroptotic processGO:006054690.815
regulation of interleukin 6 biosynthetic processGO:0045408110.815
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.815
cellular amino acid metabolic processGO:00065201030.814
positive regulation of glial cell proliferationGO:006025240.814
response to organonitrogen compoundGO:00102432460.812
Rat
mammary gland lobule developmentGO:0061377220.811
regulation of interleukin 18 productionGO:003266130.809
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.809
acute inflammatory responseGO:0002526410.808
peptidyl tyrosine modificationGO:00182121450.806
Human
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.806
isotype switching to ige isotypesGO:004828970.803
t cell activation involved in immune responseGO:0002286430.802
positive regulation of leukocyte proliferationGO:0070665730.802
interleukin 6 productionGO:0032635580.802
Rat
chemokine productionGO:0032602340.800
cell activation involved in immune responseGO:00022631260.793
t helper 1 type immune responseGO:0042088250.791
tumor necrosis factor superfamily cytokine productionGO:0071706510.789
Rat
regulation of cellular response to stressGO:00801351590.788
positive regulation of tumor necrosis factor productionGO:0032760300.786
Rat
lymphocyte migrationGO:0072676260.785
cytokine metabolic processGO:0042107710.778
positive regulation of defense response to bacteriumGO:190042610.766
positive regulation of inflammatory responseGO:0050729470.766
response to dsrnaGO:0043331300.764
positive regulation of chronic inflammatory responseGO:000267840.762
regulation of apoptotic signaling pathwayGO:20012331970.757
Mouse
acute phase responseGO:0006953100.756
regulation of lymphocyte mediated immunityGO:0002706840.756
cellular response to cytokine stimulusGO:00713451890.751
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.750
positive regulation of reactive oxygen species biosynthetic processGO:190342820.748
regulation of leukocyte mediated immunityGO:00027031040.747
positive regulation of acute inflammatory responseGO:0002675160.742
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.738
b cell activation involved in immune responseGO:0002312500.735
regulation of cellular ketone metabolic processGO:0010565660.731
nucleotide binding domain leucine rich repeat containing receptor signaling pathwayGO:003587260.730
negative regulation of multi organism processGO:0043901680.729
temperature homeostasisGO:0001659260.727
lipid localizationGO:00108761260.724
positive regulation of cellular amine metabolic processGO:003324050.723
alpha beta t cell differentiation involved in immune responseGO:0002293300.721
activation of membrane attack complexGO:000190540.721
cellular response to interleukin 1GO:007134780.719
negative regulation of necrotic cell deathGO:0060547110.715
lymphocyte mediated immunityGO:00024491390.713
Mouse
glial cell differentiationGO:00100011310.708
positive regulation of fever generationGO:003162260.707
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.707
response to bacterial lipoproteinGO:003249340.707
positive regulation of reactive oxygen species metabolic processGO:2000379110.707
t cell receptor signaling pathwayGO:0050852460.705
circadian rhythmGO:00076231140.703
Mouse
apoptotic signaling pathwayGO:00971903060.703
regulation of interleukin 10 secretionGO:200117940.702
negative regulation of odontogenesisGO:004248330.700
regulation of activated t cell proliferationGO:0046006160.699
cellular response to inorganic substanceGO:0071241370.697
Mouse
negative regulation of alpha beta t cell activationGO:0046636180.695
protein homooligomerizationGO:0051260430.692
Mouse
cd8 positive alpha beta t cell extravasationGO:003569730.689
negative regulation of growth of symbiont in hostGO:0044130190.689
extrinsic apoptotic signaling pathwayGO:00971911260.687
Mouse
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.684
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.678
regulation of secretion by cellGO:19035302490.675
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.675
Mouse
positive regulation by symbiont of host immune responseGO:005255610.668
interleukin 2 productionGO:0032623330.661
regulation of interferon beta biosynthetic processGO:004535740.661
regulation of inflammatory response to antigenic stimulusGO:0002861210.655
growth of symbiont involved in interaction with hostGO:0044116230.652
regulation of fever generationGO:003162060.652
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.652
cellular amine metabolic processGO:0044106440.647
regulation of jnk cascadeGO:0046328620.644
antimicrobial peptide biosynthetic processGO:000277720.643
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.635
response to lipoteichoic acidGO:007039160.633
regulation of ion transportGO:00432692150.625
positive regulation of t helper 1 cell differentiationGO:004562740.624
myd88 dependent toll like receptor signaling pathwayGO:000275570.622
positive regulation of protein activation cascadeGO:200025920.622
dna recombinationGO:0006310920.621
ripoptosome assemblyGO:009734360.619
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.608
t cell migrationGO:0072678190.606
regulation of reactive oxygen species metabolic processGO:2000377400.603
regulation of lymphocyte migrationGO:2000401140.599
myeloid leukocyte differentiationGO:00025731190.596
negative regulation of interleukin 6 productionGO:0032715170.593
Rat
positive regulation of immature t cell proliferationGO:003309140.593
type i interferon biosynthetic processGO:004535190.592
t cell differentiation involved in immune responseGO:0002292300.591
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.590
regulation of macrophage fusionGO:003423930.589
neuronal action potentialGO:0019228540.587
regulation of interleukin 8 productionGO:003267730.582
cd4 positive alpha beta t cell activationGO:0035710450.578
positive regulation of jnk cascadeGO:0046330460.578
follicular dendritic cell differentiationGO:000226820.569
b cell apoptotic processGO:0001783190.568
jnk cascadeGO:0007254720.563
regulation of reactive oxygen species biosynthetic processGO:190342620.562
chemokine biosynthetic processGO:004203380.560
regulation of protein import into nucleusGO:0042306520.555
Rat
immune response activating cell surface receptor signaling pathwayGO:0002429720.551
somatic diversification of immunoglobulinsGO:0016445430.551
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.549
interleukin 12 productionGO:0032615320.548
positive regulation of interferon beta biosynthetic processGO:004535930.545
leukocyte mediated immunityGO:00024431740.543
Mouse
negative regulation of glycolytic processGO:004582040.538
epithelial cell proliferationGO:00506731740.535
t helper cell differentiationGO:0042093280.534
interleukin 10 productionGO:0032613230.533
regulation of necrotic cell deathGO:0010939130.531
regulation of multi organism processGO:00439001110.524
urea cycleGO:000005020.521
regulation of mapk cascadeGO:00434082480.518
regulation of interleukin 12 productionGO:0032655300.516
cellular response to external stimulusGO:0071496880.515
Human
cd4 positive alpha beta t cell differentiationGO:0043367410.514
marginal zone b cell differentiationGO:000231520.513
positive regulation of t cell proliferationGO:0042102520.510
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.507
Mouse
gland developmentGO:00487323300.507
peptidyl amino acid modificationGO:00181933360.506
Human
reactive oxygen species metabolic processGO:0072593840.505
isotype switchingGO:0045190360.502
t cell activationGO:00421102890.502
Mouse
macrophage cytokine productionGO:001093490.500
regulation of fever generation by regulation of prostaglandin secretionGO:007181020.499
transmembrane transportGO:00550854120.495
stress activated protein kinase signaling cascadeGO:0031098810.489
positive regulation of cellular amino acid metabolic processGO:004576430.486
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.483
regulation of cell motilityGO:20001452360.481
cd4 positive alpha beta t cell lineage commitmentGO:004337360.481
regulation of t helper 1 cell differentiationGO:004562570.481
circadian temperature homeostasisGO:006008620.475
innate immune responseGO:00450871570.475
Zebrafish
myeloid dendritic cell activationGO:0001773250.473
positive regulation of cell deathGO:00109422240.471
Mouse Rat
myelinationGO:0042552740.469
cd8 positive alpha beta cytotoxic t cell extravasationGO:003569820.464
positive regulation of cell activationGO:00508671580.461
tumor necrosis factor productionGO:0032640500.461
Rat
inflammatory responseGO:00069542440.460
interleukin 8 productionGO:003263740.456
cellular response to dna damage stimulusGO:00069742070.450
monocarboxylic acid transportGO:0015718440.449
regulation of ion transmembrane transporter activityGO:0032412540.446
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.446
regulation of cell activationGO:00508652890.446
Mouse
regulation of neutrophil chemotaxisGO:0090022140.436
myeloid cell differentiationGO:00300992330.435
Mouse
negative regulation of immune system processGO:00026832090.431
Mouse
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.430
positive regulation of t cell extravasationGO:200040920.429
positive regulation of t cell migrationGO:2000406100.428
oligodendrocyte apoptotic processGO:009725210.428
mammary gland alveolus developmentGO:0060749220.428
regulation of t cell mediated immunityGO:0002709340.427
negative regulation of tumor necrosis factor productionGO:0032720170.426
positive regulation of interleukin 18 productionGO:003274120.425
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.424
regulation of interleukin 10 productionGO:0032653210.423
positive regulation of isotype switchingGO:0045830150.423
regulation of peptidyl tyrosine phosphorylationGO:0050730930.419
Human
regulation of alpha beta t cell activationGO:0046634530.419
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.415
positive regulation of interferon alpha productionGO:003272740.414
ossificationGO:00015032160.412
positive regulation of t cell activationGO:00508701010.411
regulation of production of molecular mediator of immune responseGO:0002700650.407
interleukin 23 productionGO:003262720.406
microglial cell activationGO:000177430.405
liver developmentGO:0001889660.404
induction by symbiont of host immune responseGO:005255910.403
interleukin 12 biosynthetic processGO:004209080.400
regulation of isotype switchingGO:0045191220.400
response to defense related host nitric oxide productionGO:005256520.397
regulation of fatty acid transportGO:2000191100.397
interaction with hostGO:0051701220.395
interleukin 1 mediated signaling pathwayGO:007049840.394
leukocyte differentiationGO:00025213420.392
Mouse
somatic recombination of immunoglobulin gene segmentsGO:0016447420.391
regulation of immunoglobulin productionGO:0002637420.389
axon ensheathmentGO:0008366760.387
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.385
response to interleukin 18GO:007067340.380
organic anion transportGO:00157111370.380
negative regulation of interferon gamma productionGO:0032689180.379
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005230210.377
cellular amide metabolic processGO:0043603580.376
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.375
positive regulation of atp biosynthetic processGO:200117120.374
cellular ketone metabolic processGO:0042180840.374
peptide transportGO:00158331330.369
positive regulation of interleukin 8 productionGO:003275720.367
peptidyl serine modificationGO:0018209830.365
regulation of anion transportGO:0044070270.363
ensheathment of neuronsGO:0007272760.362
positive regulation of type i interferon productionGO:0032481140.361
lymphocyte homeostasisGO:0002260640.361
Mouse
carboxylic acid transportGO:00469421000.359
defense response to virusGO:0051607680.355
regulation of chemokine productionGO:0032642300.354
cellular response to bacterial lipopeptideGO:007122130.351
positive regulation of cytokine secretionGO:0050715410.350
positive regulation of immunoglobulin mediated immune responseGO:0002891260.349
alpha beta t cell activation involved in immune responseGO:0002287310.346
regulation of interleukin 23 productionGO:003266720.346
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005226310.344
positive regulation of mapk cascadeGO:00434101700.344
type i interferon productionGO:0032606290.343
type 2 immune responseGO:0042092230.343
peptide metabolic processGO:0006518460.341
t cell mediated immunityGO:0002456500.340
negative regulation of b cell activationGO:0050869270.338
Mouse
modulation by symbiont of host immune responseGO:005255310.336
positive regulation of icosanoid secretionGO:003230570.335
lymphocyte proliferationGO:00466511640.335
response to endoplasmic reticulum stressGO:0034976530.334
regulation of immunoglobulin secretionGO:0051023120.333
positive regulation of lymphocyte mediated immunityGO:0002708620.331
regulation of b cell proliferationGO:0030888390.330
immunoglobulin productionGO:0002377730.329
Mouse
response to organic cyclic compoundGO:00140701980.328
Mouse Rat
t cell proliferationGO:00420981200.325
positive regulation of activated t cell proliferationGO:004210480.323
positive regulation of prostaglandin secretionGO:003230850.323
inflammatory response to woundingGO:009059440.322
regulation of peptide transportGO:0090087910.322
positive regulation of chemokine biosynthetic processGO:004508060.321
positive regulation of macrophage cytokine productionGO:006090770.320
regulation of kinase activityGO:00435492490.320
negative regulation of cytokine productionGO:0001818840.319
Rat
hepaticobiliary system developmentGO:0061008670.317
regulation of secretionGO:00510462740.315
response to bacterial lipopeptideGO:007033930.313
growth of symbiont in hostGO:0044117230.312
regulation of mast cell differentiationGO:006037530.308
protein oligomerizationGO:0051259670.308
Mouse Rat
regulation of syncytium formation by plasma membrane fusionGO:0060142230.305
regulation of type 2 immune responseGO:0002828180.305
protein catabolic processGO:00301632210.304
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.304
Rat
regulation of chronic inflammatory responseGO:000267670.304
regulation of natural killer cell proliferationGO:003281720.303
regulation of antimicrobial peptide biosynthetic processGO:000280510.301
antigen receptor mediated signaling pathwayGO:0050851640.299
organic acid transportGO:00158491010.296
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.296
response to granulocyte macrophage colony stimulating factorGO:009701230.292
positive regulation of apoptotic cell clearanceGO:200042730.291
regulation of tumor necrosis factor productionGO:0032680490.287
Rat
regulation of lymphocyte differentiationGO:00456191070.286
Mouse
positive regulation of isotype switching to ige isotypesGO:004829540.285
antibiotic transportGO:004289110.284
positive regulation of cd4 positive alpha beta t cell activationGO:2000516160.281
symbiosis encompassing mutualism through parasitismGO:0044403830.280
production of molecular mediator involved in inflammatory responseGO:0002532210.279
cellular response to bacterial lipoproteinGO:007122030.279
chronic inflammatory responseGO:000254490.278
regulation of membrane potentialGO:00423911920.274
positive regulation of nitric oxide synthase biosynthetic processGO:005177060.274
activation of jnkk activityGO:000725630.273
regulation of mast cell proliferationGO:007066640.272
negative regulation of lymphocyte proliferationGO:0050672450.272
regulation of chemokine secretionGO:009019640.271
regulation of mhc class ii biosynthetic processGO:004534670.269
macrophage differentiationGO:0030225200.268
negative regulation of t cell activationGO:0050868650.267
cellular extravasationGO:0045123170.267
positive regulation of response to biotic stimulusGO:0002833150.266
regulation of stress activated mapk cascadeGO:0032872690.262
positive regulation of immunoglobulin productionGO:0002639280.262
positive regulation of fatty acid transportGO:200019380.261
fatty acid derivative transportGO:1901571140.260
mapk cascadeGO:00001652810.258
heat generationGO:0031649130.258
positive regulation of interleukin 12 biosynthetic processGO:004508460.258
regulation of protein secretionGO:0050708820.257
extracellular structure organizationGO:00430621480.257
multicellular organismal signalingGO:0035637910.257
regulation of epithelial cell proliferationGO:00506781410.254
ras protein signal transductionGO:0007265770.248
regulation of nik nf kappab signalingGO:1901222100.247
positive regulation of cell migrationGO:00303351090.245
transmission of nerve impulseGO:0019226760.245
response to host immune responseGO:005257230.245
regulation of protein localizationGO:00328802310.243
Rat
interspecies interaction between organismsGO:0044419830.243
regulation of t cell extravasationGO:200040730.241
wound healing involved in inflammatory responseGO:000224640.238
regulation of immunoglobulin mediated immune responseGO:0002889370.237
regulation of cell migrationGO:00303342190.236
response to exogenous dsrnaGO:0043330220.236
follicular dendritic cell activationGO:000226620.234
organonitrogen compound biosynthetic processGO:19015661920.231
modification by symbiont of host morphology or physiologyGO:004400340.231
positive regulation of macrophage activationGO:0043032100.230
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.229
mammary gland epithelial cell proliferationGO:0033598240.228
negative regulation of chronic inflammatory responseGO:000267730.228
regulation of oligodendrocyte differentiationGO:0048713230.228
intracellular protein transportGO:00068862040.228
Rat
regulation of lymphocyte proliferationGO:00506701170.226
dna metabolic processGO:00062593030.224
anion transportGO:00068201770.220
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.219
positive regulation of lipid transportGO:0032370220.217
positive regulation of map kinase activityGO:0043406840.217

Tnfrsf1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.976
disease of anatomical entityDOID:700.976
Human
lymphatic system diseaseDOID:7500.976
retinal diseaseDOID:567900.435
sensory system diseaseDOID:005015500.435
eye and adnexa diseaseDOID:149200.435
nervous system diseaseDOID:86300.435
Human
eye diseaseDOID:561400.435
retinal degenerationDOID:846600.407
cancerDOID:16200.272
disease of cellular proliferationDOID:1456600.272