Mus musculus

321 known processes

Jak2

Janus kinase 2

(Aliases: Fd17,AI504024,C81284)

Jak2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of insulin receptor signaling pathwayGO:0046626210.999
cellular response to cytokine stimulusGO:00713451890.998
regulation of t cell differentiationGO:0045580830.997
Mouse
t cell activationGO:00421102890.997
Mouse
activation of janus kinase activityGO:004297620.995
cytokine mediated signaling pathwayGO:00192211150.994
negative regulation of insulin receptor signaling pathwayGO:0046627140.991
regulation of t helper 1 cell differentiationGO:004562570.991
Mouse
lymphocyte differentiationGO:00300982420.989
Mouse
regulation of cd4 positive alpha beta t cell activationGO:2000514240.978
Mouse
regulation of activation of jak2 kinase activityGO:001053410.977
response to peptide hormoneGO:00434341270.971
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.970
Mouse
regulation of lymphocyte activationGO:00512492400.967
Mouse
t helper cell differentiationGO:0042093280.964
Mouse
cd4 positive alpha beta t cell differentiationGO:0043367410.963
Mouse
alpha beta t cell activationGO:0046631910.959
Mouse
regulation of t cell activationGO:00508631700.959
Mouse
gland developmentGO:00487323300.957
alpha beta t cell differentiation involved in immune responseGO:0002293300.957
Mouse
regulation of cellular amino acid metabolic processGO:000652150.955
erythrocyte differentiationGO:0030218880.954
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.953
regulation of leukocyte differentiationGO:19021051590.951
Mouse
cd4 positive alpha beta t cell activationGO:0035710450.949
Mouse
cellular response to peptideGO:1901653920.947
immune response regulating signaling pathwayGO:00027641250.945
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.940
Mouse
regulation of secretionGO:00510462740.940
Rat
insulin receptor signaling pathwayGO:0008286490.939
regulation of cellular amine metabolic processGO:0033238200.937
alpha beta t cell differentiationGO:0046632690.934
Mouse
peptidyl amino acid modificationGO:00181933360.934
negative regulation of t helper 2 cell differentiationGO:004562940.932
t cell activation involved in immune responseGO:0002286430.924
Mouse
positive regulation of lymphocyte activationGO:00512511400.913
cellular amino acid metabolic processGO:00065201030.912
positive regulation of t cell differentiationGO:0045582520.901
t cell differentiationGO:00302171740.901
Mouse
response to molecule of bacterial originGO:00022371430.892
negative regulation of immune system processGO:00026832090.884
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.867
Mouse
negative regulation of cell activationGO:00508661110.864
Mouse
cellular response to peptide hormone stimulusGO:0071375920.861
positive regulation of t cell activationGO:00508701010.860
positive regulation of leukocyte differentiationGO:1902107860.856
leukocyte proliferationGO:00706611720.855
response to peptideGO:19016521360.854
regulation of kinase activityGO:00435492490.852
immune effector processGO:00022523210.850
Mouse Fly
regulation of cell activationGO:00508652890.843
Mouse Rat
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.835
Mouse
negative regulation of leukocyte differentiationGO:1902106510.829
Mouse
negative regulation of cellular response to insulin stimulusGO:1900077160.828
tyrosine phosphorylation of stat1 proteinGO:004250830.826
Rat
lactationGO:0007595250.818
regulation of t helper cell differentiationGO:0045622140.815
Mouse
peptidyl tyrosine modificationGO:00182121450.814
t helper 1 cell differentiationGO:0045063130.814
Mouse
alpha beta t cell activation involved in immune responseGO:0002287310.811
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.806
positive regulation of cell activationGO:00508671580.805
Rat
activation of immune responseGO:00022531380.803
t cell differentiation involved in immune responseGO:0002292300.801
Mouse
jak stat cascadeGO:0007259420.800
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.793
regulation of cytokine productionGO:00018172660.793
radial glia guided migration of purkinje cellGO:002194260.786
negative regulation of cellular amine metabolic processGO:003323910.760
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.757
cell activation involved in immune responseGO:00022631260.753
Mouse
lymphocyte homeostasisGO:0002260640.753
Mouse
regulation of activation of janus kinase activityGO:001053310.748
positive regulation of lymphocyte differentiationGO:0045621610.746
negative regulation of cellular amino acid metabolic processGO:004576300.734
cellular response to insulin stimulusGO:0032869780.732
positive regulation of alpha beta t cell differentiationGO:0046638280.731
amine metabolic processGO:0009308450.729
myeloid cell differentiationGO:00300992330.727
regulation of response to woundingGO:19030341890.726
Human Rat
regulation of body fluid levelsGO:00508781620.719
negative regulation of t cell activationGO:0050868650.718
Mouse
positive regulation of cytokine productionGO:00018191740.714
positive regulation of apoptotic processGO:00430652170.706
regulation of alpha beta t cell activationGO:0046634530.697
Mouse
adaptive immune responseGO:00022501550.697
Mouse
negative regulation of lymphocyte differentiationGO:0045620320.696
Mouse
lymphocyte mediated immunityGO:00024491390.694
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.693
stem cell differentiationGO:00488632680.685
Fly
positive regulation of protein phosphorylationGO:00019342420.678
leukocyte activation involved in immune responseGO:00023661260.661
Mouse
response to interferon gammaGO:0034341340.654
Rat
positive regulation of transferase activityGO:00513471670.646
mitotic cell cycleGO:00002781950.643
homeostasis of number of cellsGO:00488722100.642
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.639
immune response regulating cell surface receptor signaling pathwayGO:0002768800.634
t cell proliferationGO:00420981200.627
regulation of antigen receptor mediated signaling pathwayGO:0050854290.626
positive regulation of cd4 positive alpha beta t cell differentiationGO:0043372140.614
tyrosine phosphorylation of stat5 proteinGO:004250690.614
cellular response to organonitrogen compoundGO:00714171450.614
regulation of alpha beta t cell differentiationGO:0046637350.609
Mouse
layer formation in cerebral cortexGO:0021819130.606
t cell receptor signaling pathwayGO:0050852460.605
regulation of protein kinase activityGO:00458592320.604
cellular response to hormone stimulusGO:00328701500.602
response to lipopolysaccharideGO:00324961280.602
negative regulation of cellular protein metabolic processGO:00322692470.596
immune response activating signal transductionGO:00027571160.595
regulation of type 2 immune responseGO:0002828180.590
negative regulation of tyrosine phosphorylation of stat3 proteinGO:004251810.589
response to insulinGO:00328681000.571
lymphocyte activation involved in immune responseGO:0002285930.570
Mouse
mammary gland epithelium developmentGO:0061180650.561
regulation of cellular ketone metabolic processGO:0010565660.561
nuclear divisionGO:00002801580.553
regulation of lymphocyte differentiationGO:00456191070.551
Mouse
cellular response to lipopolysaccharideGO:0071222770.548
regulation of transferase activityGO:00513382630.546
response to amino acidGO:0043200370.544
response to organonitrogen compoundGO:00102432460.543
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516100.536
regulation of cell cycle processGO:00105641600.527
regulation of adaptive immune responseGO:0002819900.524
Mouse
cellular response to amino acid stimulusGO:0071230290.523
response to interleukin 6GO:0070741100.521
b cell activationGO:00421131610.514
Mouse
regulation of cell cycleGO:00517262810.507
negative regulation of immune effector processGO:0002698550.505
Mouse
positive regulation of cd4 positive alpha beta t cell activationGO:2000516160.502
exocytosisGO:00068871210.499
negative regulation of t helper cell differentiationGO:004562390.490
Mouse
fat cell differentiationGO:00454441600.479
regulation of establishment of protein localizationGO:00702011810.477
Rat
protein secretionGO:00093061110.477
protein processingGO:00164851630.472
cytokine productionGO:00018163190.467
cellular response to molecule of bacterial originGO:0071219830.451
regulation of t helper 1 type immune responseGO:0002825170.451
Mouse
negative regulation of cd4 positive alpha beta t cell activationGO:2000515100.448
Mouse
antigen receptor mediated signaling pathwayGO:0050851640.447
regulation of inflammatory responseGO:00507271470.447
Human Rat
tyrosine phosphorylation of stat3 proteinGO:0042503120.444
response to interleukin 15GO:007067230.439
regulation of cellular response to insulin stimulusGO:1900076300.438
leukocyte differentiationGO:00025213420.437
Mouse
regulation of jak stat cascadeGO:0046425340.436
positive regulation of protein modification processGO:00314012990.418
negative regulation of phosphorylationGO:00423261660.416
positive regulation of t helper 1 cell differentiationGO:004562740.413
regulation of leukocyte apoptotic processGO:2000106560.411
Mouse
stem cell developmentGO:00488642190.409
Fly
natural killer cell proliferationGO:000178730.408
chemotaxisGO:00069352470.408
lymphocyte proliferationGO:00466511640.403
response to ketoneGO:1901654150.395
cellular ketone metabolic processGO:0042180840.391
regulation of proteolysisGO:00301621640.389
regulation of innate immune responseGO:0045088910.389
organ regenerationGO:003110020.385
negative regulation of protein metabolic processGO:00512482820.383
Mouse
negative regulation of molecular functionGO:00440922580.380
sensory organ morphogenesisGO:00905962420.379
Fly
neuron deathGO:00709971540.378
Rat
cellular response to interferon gammaGO:0071346250.375
Rat
negative regulation of phosphate metabolic processGO:00459361840.366
regulation of exocytosisGO:0017157610.363
positive regulation of hydrolase activityGO:00513451480.361
regulation of secretion by cellGO:19035302490.361
Rat
negative regulation of alpha beta t cell activationGO:0046636180.355
Mouse
organelle fissionGO:00482851700.354
regulation of endopeptidase activityGO:0052548890.352
negative regulation of lymphocyte activationGO:0051250910.348
Mouse
cellular response to lipidGO:00713961450.346
protein modification by small protein conjugationGO:00324461870.334
protein localization to nucleusGO:00345041210.333
negative regulation of phosphorus metabolic processGO:00105631840.332
positive regulation of apoptotic signaling pathwayGO:2001235950.330
regulation of bindingGO:00510981110.329
regulation of leukocyte mediated immunityGO:00027031040.327
Mouse
learning or memoryGO:00076111480.324
Fly
positive regulation of immune effector processGO:00026991070.323
cellular response to interleukin 6GO:007135490.321
negative regulation of t cell differentiationGO:0045581230.320
Mouse
digestive system developmentGO:00551232000.314
Fly
regulation of defense responseGO:00313472330.309
Human Rat
negative regulation of protein phosphorylationGO:00019331260.308
regulation of production of molecular mediator of immune responseGO:0002700650.308
Mouse
production of molecular mediator of immune responseGO:00024401030.307
Mouse
regulation of organelle organizationGO:00330432890.307
carbohydrate metabolic processGO:00059752300.302
cell divisionGO:00513011200.301
regulation of vesicle mediated transportGO:00606271390.300
actin cytoskeleton organizationGO:00300362200.298
inflammatory responseGO:00069542440.296
Human Rat
positive regulation of alpha beta t cell activationGO:0046635390.296
innate immune responseGO:00450871570.295
Rat
t helper 1 type immune responseGO:0042088250.294
Mouse
cerebral cortex radial glia guided migrationGO:0021801170.293
peptidyl tyrosine phosphorylationGO:00181081430.293
dna metabolic processGO:00062593030.293
myeloid cell homeostasisGO:00022621140.289
b cell differentiationGO:0030183780.287
Mouse
tyrosine phosphorylation of stat proteinGO:0007260230.286
negative regulation of protein modification processGO:00314001630.286
wound healingGO:00420601570.285
positive regulation of cellular amine metabolic processGO:003324050.284
glycoprotein biosynthetic processGO:0009101890.283
Mouse
regulation of peptidase activityGO:0052547960.282
regulation of t helper 2 cell differentiationGO:004562880.281
regulation of nuclear divisionGO:0051783560.280
type 2 immune responseGO:0042092230.280
apical constrictionGO:000338340.280
Fly
regulation of neuron differentiationGO:00456642810.279
retina morphogenesis in camera type eyeGO:0060042450.278
positive regulation of cell deathGO:00109422240.278
regulation of hydrolase activityGO:00513362460.273
cellular amine metabolic processGO:0044106440.268
t helper 2 cell differentiationGO:0045064120.263
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.262
immune response activating cell surface receptor signaling pathwayGO:0002429720.261
actin cytoskeleton reorganizationGO:0031532210.261
negative regulation of cellular component organizationGO:00511291940.257
syncytium formationGO:0006949430.252
multicellular organism growthGO:00352641610.246
response to acid chemicalGO:00011011110.245
urogenital system developmentGO:00016552610.245
carbohydrate derivative biosynthetic processGO:19011371830.243
Mouse
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.243
skin developmentGO:00435882200.242
mammary gland morphogenesisGO:0060443540.242
regulation of mitotic cell cycleGO:00073461260.240
positive regulation of nervous system developmentGO:00519622210.240
response to organic cyclic compoundGO:00140701980.239
stem cell maintenanceGO:00198271300.239
Fly
myeloid leukocyte activationGO:0002274830.234
leukocyte homeostasisGO:0001776790.233
Mouse
epidermis developmentGO:00085441870.229
regulation of immunoglobulin productionGO:0002637420.225
epidermal growth factor receptor signaling pathwayGO:0007173280.223
positive regulation of organelle organizationGO:00106381280.222
respiratory system developmentGO:00605411900.221
Fly
response to steroid hormoneGO:0048545560.220
body fluid secretionGO:0007589530.217
cation transportGO:00068123990.215
natural killer cell activationGO:0030101440.206
positive regulation of insulin receptor signaling pathwayGO:004662840.206
hindbrain radial glia guided cell migrationGO:0021932120.205
regulation of peptidyl tyrosine phosphorylationGO:0050730930.205
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.204
eye photoreceptor cell differentiationGO:0001754410.203
Fly
negative regulation of response to cytokine stimulusGO:006076190.201
cell fate commitmentGO:00451652100.199
cytosolic calcium ion homeostasisGO:0051480700.199
Rat
transmission of nerve impulseGO:0019226760.195
digestive tract developmentGO:00485651900.194
Fly
camera type eye developmentGO:00430102660.194
mapk cascadeGO:00001652810.193
Rat
placenta blood vessel developmentGO:0060674310.192
cellular response to organic cyclic compoundGO:0071407870.191
negative regulation of intracellular signal transductionGO:19025321670.191
g protein coupled receptor signaling pathwayGO:00071862430.188
Rat
negative regulation of t helper 1 cell differentiationGO:004562630.188
Mouse
erbb signaling pathwayGO:0038127320.187
epithelial cell developmentGO:00020641590.185
Fly
negative regulation of t cell apoptotic processGO:0070233180.182
Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.181
spongiotrophoblast layer developmentGO:0060712150.181
interferon gamma mediated signaling pathwayGO:006033350.178
Rat
regulation of protein secretionGO:0050708820.178
lung cell differentiationGO:0060479300.178
protein modification by small protein conjugation or removalGO:00706472070.176
positive regulation of kinase activityGO:00336741550.174
cellular carbohydrate metabolic processGO:00442621190.171
regulation of mapk cascadeGO:00434082480.170
Rat
protein localization to organelleGO:00333651850.170
interleukin 2 mediated signaling pathwayGO:003811020.170
embryonic placenta developmentGO:0001892980.169
negative regulation of jak stat cascadeGO:004642670.167
regulation of protein localizationGO:00328802310.167
Rat
regulation of neuron apoptotic processGO:00435231220.164
Rat
cellular response to growth hormone stimulusGO:007137870.164
regulation of cell sizeGO:0008361720.162
positive regulation of programmed cell deathGO:00430682180.160
small gtpase mediated signal transductionGO:0007264970.159
positive regulation of cell developmentGO:00107202370.159
positive regulation of mitotic cell cycleGO:0045931410.159
hematopoietic stem cell migrationGO:003570110.159
negative regulation of type 2 immune responseGO:000282980.159
protein maturationGO:00516041760.158
purine containing compound metabolic processGO:00725213110.157
mitotic cell cycle processGO:19030471590.157
i kappab kinase nf kappab signalingGO:0007249850.153
protein ubiquitinationGO:00165671710.150
positive regulation of cysteine type endopeptidase activityGO:2001056390.150
leukocyte apoptotic processGO:0071887710.150
Mouse
leukocyte mediated immunityGO:00024431740.148
Mouse
cytoplasmic transportGO:00164822340.148
dna recombinationGO:0006310920.147
negative regulation of alpha beta t cell differentiationGO:0046639120.146
Mouse
negative regulation of synaptic vesicle transportGO:190280430.145
muscle cell differentiationGO:00426922610.144
regulation of mast cell activationGO:0033003210.143
apoptotic signaling pathwayGO:00971903060.143
positive regulation of mapk cascadeGO:00434101700.143
Rat
establishment of organelle localizationGO:00516561220.142
regulation of cellular component sizeGO:00325351210.142
positive regulation of cellular amino acid metabolic processGO:004576430.142
retina development in camera type eyeGO:00600411190.141
microtubule cytoskeleton organizationGO:00002261570.141
positive regulation of proteolysisGO:0045862850.140
hindbrain developmentGO:00309021280.140
actin filament organizationGO:00070151130.138
divalent inorganic cation transportGO:00725111780.137
cellular homeostasisGO:00197252400.135
Rat
t cell differentiation in thymusGO:0033077770.132
long term memoryGO:0007616150.132
Fly
metal ion homeostasisGO:00550651890.130
Rat
positive regulation of secretionGO:00510471300.129
Rat
positive regulation of defense responseGO:00313491240.129
Rat
lung developmentGO:00303241640.128
glial cell differentiationGO:00100011310.127
cellular response to interleukin 4GO:0071353210.127
rhythmic processGO:00485111740.125
Fly
positive regulation of secretion by cellGO:19035321140.125
Rat
t cell homeostasisGO:0043029350.125
Mouse
placenta developmentGO:00018901400.125
mitotic nuclear divisionGO:0007067480.123
organelle localizationGO:00516401790.123
negative regulation of homeostatic processGO:0032845710.123
negative regulation of cell proliferationGO:00082852960.123
coagulationGO:0050817780.122
positive regulation of intracellular transportGO:0032388700.121
Rat
extrinsic apoptotic signaling pathwayGO:00971911260.121
blood vessel morphogenesisGO:00485142850.121
immunoglobulin mediated immune responseGO:0016064690.120
regulation of anatomical structure sizeGO:00900661780.118
cytokine secretionGO:0050663720.117
calcium ion homeostasisGO:00550741270.117
Rat
regulation of protein complex assemblyGO:0043254830.117
regulation of leukocyte mediated cytotoxicityGO:0001910380.116
digestive tract morphogenesisGO:00485461470.116
Fly
monosaccharide metabolic processGO:00059961060.116
activation of cysteine type endopeptidase activityGO:0097202270.115
t cell mediated immunityGO:0002456500.115
regulation of b cell activationGO:0050864810.115
zymogen activationGO:0031638410.114
negative regulation of antigen receptor mediated signaling pathwayGO:0050858160.114
immunoglobulin productionGO:0002377730.113
lateral line system developmentGO:004892510.113
neurotransmitter secretionGO:0007269620.113
tissue remodelingGO:00487711020.113
regulation of interferon gamma mediated signaling pathwayGO:006033430.111
t cell apoptotic processGO:0070231390.109
Mouse
leukocyte mediated cytotoxicityGO:0001909620.108
myeloid leukocyte differentiationGO:00025731190.106
myotube differentiationGO:00149021050.106
positive regulation of protein kinase activityGO:00458601440.105
negative regulation of cd4 positive alpha beta t cell differentiationGO:004337190.105
Mouse
positive regulation of jak stat cascadeGO:0046427220.105
response to alcoholGO:0097305480.103
regulation of t cell receptor signaling pathwayGO:0050856210.103
regulation of sequence specific dna binding transcription factor activityGO:00510901060.103
Rat
positive regulation of leukocyte proliferationGO:0070665730.102
maintenance of locationGO:0051235890.101
cellular response to interleukin 15GO:007135020.101
embryonic hemopoiesisGO:0035162230.101
actin filament based movementGO:0030048230.100
Fly
regulation of cytokine secretionGO:0050707610.100
rho protein signal transductionGO:0007266320.100
somatic diversification of immune receptorsGO:0002200530.100
blood coagulationGO:0007596760.099
calcium ion transportGO:00068161590.098
positive regulation of lymphocyte proliferationGO:0050671700.098
response to interleukin 4GO:0070670230.097
regulation of b cell differentiationGO:0045577230.097
cerebral cortex radially oriented cell migrationGO:0021799310.096
regulation of cell motilityGO:20001452360.095
Rat
regulation of protein processingGO:0070613960.095
endomembrane system organizationGO:00102561470.095
regulation of nucleoside metabolic processGO:00091181300.094
negative regulation of growthGO:0045926990.094
regulation of cell shapeGO:0008360390.094
Fly
dna biosynthetic processGO:0071897220.093
macromolecule methylationGO:00434141200.093
negative regulation of synaptic vesicle exocytosisGO:200030130.093
lymphocyte apoptotic processGO:0070227540.093
Mouse
forebrain cell migrationGO:0021885580.093
nucleoside phosphate metabolic processGO:00067533380.093
regulation of lymphocyte apoptotic processGO:0070228410.092
Mouse
interleukin 4 mediated signaling pathwayGO:003577120.092
protein autophosphorylationGO:0046777610.090
regulation of membrane potentialGO:00423911920.090
cerebral cortex developmentGO:0021987860.089
b cell mediated immunityGO:0019724710.089
columnar cuboidal epithelial cell differentiationGO:0002065820.089
Fly
erk1 and erk2 cascadeGO:0070371770.089
synaptic transmissionGO:00072683290.087
multicellular organismal signalingGO:0035637910.086
regulation of response to cytokine stimulusGO:0060759230.086
cellular divalent inorganic cation homeostasisGO:00725031270.086
Rat
response to interleukin 2GO:007066920.086
photoreceptor cell differentiationGO:0046530520.086
Fly
generation of precursor metabolites and energyGO:00060911030.086
regulation of mast cell proliferationGO:007066640.086
mammary gland alveolus developmentGO:0060749220.086
hematopoietic progenitor cell differentiationGO:00022441430.085
regulation of wnt signaling pathwayGO:00301111230.085
nuclear importGO:0051170950.085
activation of jak2 kinase activityGO:004297720.084
striated muscle tissue developmentGO:00147062930.084
positive regulation of cell cycleGO:0045787920.084
t cell selectionGO:0045058340.084
negative regulation of hydrolase activityGO:0051346710.084
regulation of protein serine threonine kinase activityGO:00719001570.083
Rat
regulation of t cell differentiation in thymusGO:0033081240.083
telencephalon cell migrationGO:0022029550.083
cell differentiation involved in embryonic placenta developmentGO:0060706260.083
regulation of myeloid cell differentiationGO:0045637960.083
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.083
Mouse
labyrinthine layer developmentGO:0060711490.083
regulation of endocytosisGO:0030100690.082
dendritic cell apoptotic processGO:009704830.082
Mouse
positive regulation of growth hormone receptor signaling pathwayGO:006039930.082
carbohydrate homeostasisGO:00335001280.082
positive regulation of neuron differentiationGO:00456661410.081
regulation of protein transportGO:00512231630.081
Rat
lung epithelium developmentGO:0060428370.080
b cell proliferationGO:0042100530.080
positive regulation of adaptive immune responseGO:0002821610.080
mammary gland lobule developmentGO:0061377220.079
regulation of cell divisionGO:0051302760.079
regulation of protein tyrosine kinase activityGO:0061097170.077
angiogenesisGO:00015252010.077
pallium developmentGO:00215431200.077
organic cyclic compound catabolic processGO:19013612950.077
negative regulation of myeloid cell differentiationGO:0045638380.076
guanosine containing compound catabolic processGO:19010691440.076
embryonic organ morphogenesisGO:00485622760.076
negative regulation of protein maturationGO:1903318790.076
regulation of myeloid leukocyte differentiationGO:0002761580.076
positive regulation of endopeptidase activityGO:0010950430.076
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.075
Mouse
mast cell proliferationGO:007066240.075
gtp catabolic processGO:00061841430.075
regulation of mitosisGO:0007088290.075
negative regulation of defense responseGO:0031348770.074
sensory system developmentGO:004888030.073
glucose homeostasisGO:00425931280.073
response to progesteroneGO:003257010.073
protein targetingGO:00066051430.072
gliogenesisGO:00420631410.072
defense response to other organismGO:00985421970.071
Fly
regenerationGO:0031099380.070
Rat
lateral inhibitionGO:004633110.070
somatic cell dna recombinationGO:0016444510.070
positive regulation of t helper cell differentiationGO:004562490.070
male gamete generationGO:00482322850.070
mesenchymal cell differentiationGO:00487621070.069
cellular protein catabolic processGO:00442571550.069
protein importGO:00170381010.068
positive regulation of gamma delta t cell differentiationGO:004558860.068
histone modificationGO:00165701590.068
Human
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.068
regulation of response to interferon gammaGO:006033030.068
cerebral cortex cell migrationGO:0021795440.068
extracellular structure organizationGO:00430621480.067
response to granulocyte macrophage colony stimulating factorGO:009701230.067
sulfur compound metabolic processGO:00067901000.066
leukocyte degranulationGO:0043299270.066
regulation of cellular component biogenesisGO:00440871810.066
platelet aggregationGO:0070527200.066
regulation of mast cell activation involved in immune responseGO:0033006170.066
liver developmentGO:0001889660.066
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.066
single organism nuclear importGO:1902593950.065
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.065
Rat
negative regulation of t cell mediated cytotoxicityGO:000191530.065
type i interferon signaling pathwayGO:0060337100.064
b cell homeostasisGO:0001782340.064
morphogenesis of a branching epitheliumGO:00611381930.064
branching involved in labyrinthine layer morphogenesisGO:006067090.063
divalent inorganic cation homeostasisGO:00725071380.063
Rat
blastocyst developmentGO:0001824800.062
actin filament bundle assemblyGO:0051017400.062
synaptic vesicle localizationGO:0097479590.062
convergent extensionGO:0060026140.062
Fly
embryonic placenta morphogenesisGO:0060669250.061

Jak2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.138
Human
disease of cellular proliferationDOID:1456600.138
Human
immune system diseaseDOID:291400.096
Human
disease of anatomical entityDOID:700.096
Human
hematopoietic system diseaseDOID:7400.096
Human
organ system cancerDOID:005068600.090
Human
immune system cancerDOID:006008300.078
Human