Mus musculus

281 known processes

Jak3

Janus kinase 3

(Aliases: wil,fae)

Jak3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myeloid leukocyte differentiationGO:00025731190.606
regulation of lymphocyte differentiationGO:00456191070.561
lymphocyte differentiationGO:00300982420.555
regulation of leukocyte differentiationGO:19021051590.554
t cell differentiationGO:00302171740.542
homeostasis of number of cellsGO:00488722100.531
leukocyte mediated immunityGO:00024431740.517
negative regulation of myeloid cell differentiationGO:0045638380.489
carbohydrate metabolic processGO:00059752300.464
alpha beta t cell differentiationGO:0046632690.456
regulation of cell activationGO:00508652890.456
t cell activationGO:00421102890.455
inflammatory responseGO:00069542440.411
glycoprotein biosynthetic processGO:0009101890.398
cytokine mediated signaling pathwayGO:00192211150.393
myeloid leukocyte activationGO:0002274830.387
alpha beta t cell differentiation involved in immune responseGO:0002293300.378
negative regulation of leukocyte differentiationGO:1902106510.369
positive regulation of lymphocyte activationGO:00512511400.366
Rat
t cell differentiation involved in immune responseGO:0002292300.359
positive regulation of apoptotic processGO:00430652170.349
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.320
dendritic cell differentiationGO:0097028260.311
regulation of insulin receptor signaling pathwayGO:0046626210.304
leukocyte homeostasisGO:0001776790.300
adaptive immune responseGO:00022501550.296
forebrain developmentGO:00309003020.293
t helper cell differentiationGO:0042093280.289
leukocyte differentiationGO:00025213420.282
gland developmentGO:00487323300.275
Mouse Fly
cd4 positive alpha beta t cell differentiationGO:0043367410.264
cellular amine metabolic processGO:0044106440.256
immunoglobulin mediated immune responseGO:0016064690.254
negative regulation of growthGO:0045926990.253
myeloid cell homeostasisGO:00022621140.250
Mouse
positive regulation of programmed cell deathGO:00430682180.250
carbohydrate derivative biosynthetic processGO:19011371830.246
alpha beta t cell activationGO:0046631910.224
skin developmentGO:00435882200.219
defense response to other organismGO:00985421970.214
Fly
positive regulation of leukocyte differentiationGO:1902107860.213
t cell differentiation in thymusGO:0033077770.208
Zebrafish
cellular response to peptideGO:1901653920.207
Mouse
negative regulation of myeloid leukocyte differentiationGO:0002762200.206
positive regulation of t cell activationGO:00508701010.205
Rat
immune effector processGO:00022523210.199
b cell differentiationGO:0030183780.196
positive regulation of cell activationGO:00508671580.179
Rat
t helper 1 type immune responseGO:0042088250.176
regulation of inflammatory responseGO:00507271470.172
coagulationGO:0050817780.169
regulation of protein localizationGO:00328802310.169
positive regulation of mapk cascadeGO:00434101700.167
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.163
erythrocyte differentiationGO:0030218880.154
Mouse
cd4 positive alpha beta t cell activationGO:0035710450.150
regulation of cd4 positive alpha beta t cell activationGO:2000514240.150
leukocyte migrationGO:00509001240.148
apoptotic signaling pathwayGO:00971903060.147
positive regulation of t cell differentiationGO:0045582520.146
regulation of cytokine productionGO:00018172660.146
leukocyte proliferationGO:00706611720.144
Rat
regulation of leukocyte apoptotic processGO:2000106560.144
activation of immune responseGO:00022531380.142
germ cell developmentGO:00072811850.141
Fly
myeloid dendritic cell activationGO:0001773250.140
regulation of myeloid leukocyte differentiationGO:0002761580.137
defense response to virusGO:0051607680.134
Fly
regulation of lymphocyte proliferationGO:00506701170.130
Rat
lipopolysaccharide mediated signaling pathwayGO:0031663250.130
positive regulation of cell developmentGO:00107202370.130
hair follicle developmentGO:0001942850.129
regulation of membrane potentialGO:00423911920.129
alpha beta t cell activation involved in immune responseGO:0002287310.127
response to organonitrogen compoundGO:00102432460.125
Mouse
immune response activating cell surface receptor signaling pathwayGO:0002429720.123
cellular response to molecule of bacterial originGO:0071219830.123
Mouse
negative regulation of cytokine productionGO:0001818840.122
regulation of apoptotic signaling pathwayGO:20012331970.122
dna metabolic processGO:00062593030.122
b cell activationGO:00421131610.120
cellular response to organonitrogen compoundGO:00714171450.118
Mouse
cellular response to peptide hormone stimulusGO:0071375920.118
Mouse
regulation of alpha beta t cell differentiationGO:0046637350.118
positive regulation of chemotaxisGO:0050921380.117
negative regulation of cell activationGO:00508661110.116
extracellular matrix organizationGO:00301981470.115
modulation of growth of symbiont involved in interaction with hostGO:0044144190.113
positive regulation of monocyte chemotaxisGO:009002620.112
t cell receptor signaling pathwayGO:0050852460.111
positive regulation of myeloid leukocyte differentiationGO:0002763260.110
positive regulation of cell deathGO:00109422240.109
regulation of cell motilityGO:20001452360.106
positive regulation of cellular amine metabolic processGO:003324050.106
negative regulation of cell proliferationGO:00082852960.105
Mouse
nucleoside triphosphate metabolic processGO:00091412300.105
epithelial cell proliferationGO:00506731740.104
i kappab kinase nf kappab signalingGO:0007249850.104
epithelial tube morphogenesisGO:00605623030.102
cellular amino acid metabolic processGO:00065201030.102
cellular response to dna damage stimulusGO:00069742070.101
blood vessel morphogenesisGO:00485142850.101
t cell selectionGO:0045058340.101
positive regulation of neutrophil chemotaxisGO:0090023120.101
cytokine secretionGO:0050663720.101
lymphocyte proliferationGO:00466511640.101
Rat
negative regulation of immune system processGO:00026832090.100
regulation of innate immune responseGO:0045088910.098
regulation of cellular component biogenesisGO:00440871810.098
regulation of t cell activationGO:00508631700.098
germinal center formationGO:0002467160.098
cell fate commitmentGO:00451652100.098
regulation of t cell differentiationGO:0045580830.097
negative regulation of defense responseGO:0031348770.095
glycoprotein metabolic processGO:00091001160.095
positive regulation of insulin receptor signaling pathwayGO:004662840.094
regulation of myeloid cell differentiationGO:0045637960.093
extracellular structure organizationGO:00430621480.093
regulation of tumor necrosis factor productionGO:0032680490.093
Mouse
cellularizationGO:000734910.093
regulation of bindingGO:00510981110.092
Mouse
sensory perceptionGO:00076002450.092
regulation of cell cycleGO:00517262810.091
cation homeostasisGO:00550802120.091
Rat
mapk cascadeGO:00001652810.090
axon guidanceGO:00074111410.090
positive regulation of transferase activityGO:00513471670.090
Mouse
protein catabolic processGO:00301632210.090
cellular response to hormone stimulusGO:00328701500.089
Mouse
regulation of cellular ketone metabolic processGO:0010565660.089
extrinsic apoptotic signaling pathwayGO:00971911260.089
regulation of carbohydrate biosynthetic processGO:0043255400.089
epidermis developmentGO:00085441870.088
neuron projection guidanceGO:00974851410.088
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.088
regulation of sequence specific dna binding transcription factor activityGO:00510901060.087
regulation of toll like receptor signaling pathwayGO:0034121200.086
positive regulation of monocyte extravasationGO:200043910.085
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.085
regulation of multi organism processGO:00439001110.084
response to lipopolysaccharideGO:00324961280.082
Mouse
myeloid leukocyte mediated immunityGO:0002444420.082
regulation of erythrocyte differentiationGO:0045646230.081
macromolecule glycosylationGO:0043413550.080
positive regulation of nervous system developmentGO:00519622210.080
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.080
exocrine system developmentGO:0035272450.080
myeloid leukocyte migrationGO:0097529570.079
small gtpase mediated signal transductionGO:0007264970.079
regulation of cell shapeGO:0008360390.079
Fly
production of molecular mediator of immune responseGO:00024401030.078
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.077
positive regulation of organelle organizationGO:00106381280.077
insulin receptor signaling pathwayGO:0008286490.077
regulation of protein secretionGO:0050708820.075
mast cell proliferationGO:007066240.075
glycosylationGO:0070085620.075
positive regulation of behaviorGO:0048520400.074
purine ribonucleoside metabolic processGO:00461282410.074
protein glycosylationGO:0006486550.073
cytokine biosynthetic processGO:0042089680.072
morphogenesis of a branching structureGO:00017632030.071
nuclear divisionGO:00002801580.070
carbohydrate transportGO:0008643620.070
b cell mediated immunityGO:0019724710.069
regulation of organelle organizationGO:00330432890.069
cellular response to cytokine stimulusGO:00713451890.069
myeloid cell differentiationGO:00300992330.068
Mouse
positive regulation of alpha beta t cell activationGO:0046635390.068
lymphocyte homeostasisGO:0002260640.068
morphogenesis of a branching epitheliumGO:00611381930.068
positive regulation of cell motilityGO:20001471160.068
positive regulation of production of molecular mediator of immune responseGO:0002702450.067
salivary gland developmentGO:0007431370.067
amine metabolic processGO:0009308450.067
sensory perception of mechanical stimulusGO:00509541070.067
regulation of cellular amine metabolic processGO:0033238200.067
organelle assemblyGO:00709251770.066
regionalizationGO:00030023370.066
Fly
b cell homeostasisGO:0001782340.065
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.065
negative regulation of apoptotic signaling pathwayGO:20012341040.064
macromolecule catabolic processGO:00090572810.064
forebrain cell migrationGO:0021885580.064
regulation of cell migrationGO:00303342190.064
engulfment of apoptotic cellGO:004365230.064
negative regulation of growth of symbiont in hostGO:0044130190.063
regulation of antimicrobial humoral responseGO:000275930.063
negative regulation of cytokine biosynthetic processGO:0042036130.062
negative regulation of protein metabolic processGO:00512482820.062
positive regulation of neutrophil migrationGO:1902624120.062
positive regulation of protein kinase b signalingGO:0051897320.062
response to protozoanGO:0001562280.062
regulation of dendritic cell chemotaxisGO:200050810.062
gonad developmentGO:00084061410.062
cell activation involved in immune responseGO:00022631260.062
positive regulation of lymphocyte differentiationGO:0045621610.061
divalent metal ion transportGO:00708381720.061
Rat
molting cycleGO:0042303900.061
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.061
myeloid dendritic cell differentiationGO:0043011160.061
cerebral cortex radially oriented cell migrationGO:0021799310.060
multicellular organismal homeostasisGO:00488711640.060
exocytosisGO:00068871210.059
protein maturationGO:00516041760.059
Mouse
regulation of dendritic cell apoptotic processGO:200066830.059
leukocyte apoptotic processGO:0071887710.058
growth involved in symbiotic interactionGO:0044110230.057
regulation of acute inflammatory responseGO:0002673270.056
response to peptide hormoneGO:00434341270.056
Mouse
regulation of cd8 positive alpha beta t cell activationGO:200118530.056
immune response activating signal transductionGO:00027571160.056
chemotaxisGO:00069352470.056
positive regulation of cell migrationGO:00303351090.055
stem cell differentiationGO:00488632680.055
Fly
regulation of lymphocyte activationGO:00512492400.055
striated muscle tissue developmentGO:00147062930.054
regulation of lipid metabolic processGO:00192161180.054
interleukin 4 productionGO:0032633240.053
toll like receptor 4 signaling pathwayGO:003414290.053
positive regulation of t helper 1 cell differentiationGO:004562740.053
divalent inorganic cation transportGO:00725111780.052
Rat
regulation of cell projection assemblyGO:0060491380.052
mature dendritic cell differentiationGO:009702930.052
lymph node developmentGO:0048535180.052
positive regulation of hydrolase activityGO:00513451480.052
Mouse
positive regulation of reactive oxygen species biosynthetic processGO:190342820.052
developmental maturationGO:00217001930.052
type i interferon signaling pathwayGO:0060337100.051
regulation of protein catabolic processGO:00421761080.051
sequestering of metal ionGO:0051238190.051
epithelial cell developmentGO:00020641590.051
Fly
nucleotide metabolic processGO:00091173320.051
keratinocyte differentiationGO:0030216480.050
axonogenesisGO:00074092740.050
positive regulation of angiogenesisGO:0045766460.050
tumor necrosis factor superfamily cytokine productionGO:0071706510.050
Mouse
helper t cell chemotaxisGO:003570410.050
lymphocyte activation involved in immune responseGO:0002285930.050
cell type specific apoptotic processGO:00972852680.049
positive regulation of innate immune responseGO:0045089800.048
regulation of cytokine biosynthetic processGO:0042035590.048
development of primary sexual characteristicsGO:00451371430.047
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.047
Mouse
internal peptidyl lysine acetylationGO:0018393420.047
positive regulation of cd4 positive alpha beta t cell differentiationGO:0043372140.047
interferon gamma productionGO:0032609670.047
positive regulation of cellular component biogenesisGO:0044089940.047
positive regulation of gamma delta t cell differentiationGO:004558860.047
regulation of cell adhesionGO:00301551540.046
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.046
regulation of mast cell proliferationGO:007066640.046
release of sequestered calcium ion into cytosolGO:0051209420.046
ras protein signal transductionGO:0007265770.045
t helper 17 cell lineage commitmentGO:007254040.045
positive regulation of secretion by cellGO:19035321140.045
muscle cell differentiationGO:00426922610.045
t cell activation involved in immune responseGO:0002286430.045
salivary gland morphogenesisGO:0007435330.045
somatic recombination of immunoglobulin gene segmentsGO:0016447420.044
establishment of organelle localizationGO:00516561220.044
defense response to protozoanGO:0042832250.044
regulation of alpha beta t cell activationGO:0046634530.044
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.044
lymphocyte mediated immunityGO:00024491390.044
compound eye developmentGO:004874910.044
Fly
dna damage response signal transduction by p53 class mediatorGO:0030330190.044
neuron migrationGO:00017641220.044
protein acylationGO:0043543640.043
regulation of immunoglobulin mediated immune responseGO:0002889370.043
regulation of response to woundingGO:19030341890.043
erk1 and erk2 cascadeGO:0070371770.043
regulation of alpha beta t cell proliferationGO:0046640180.043
regulation of gamma delta t cell activationGO:004664390.043
neutrophil chemotaxisGO:0030593360.043
positive regulation of defense responseGO:00313491240.043
regulation of hydrolase activityGO:00513362460.042
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.042
acute inflammatory responseGO:0002526410.042
regulation of toll like receptor 2 signaling pathwayGO:003413530.042
regulation of cell projection organizationGO:00313442060.042
carbohydrate biosynthetic processGO:0016051740.042
regulation of striated muscle cell differentiationGO:0051153810.041
regulation of defense responseGO:00313472330.041
t cell proliferationGO:00420981200.041
Rat
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.040
positive regulation of myeloid cell differentiationGO:0045639430.040
positive regulation of regulatory t cell differentiationGO:004559140.040
blood coagulationGO:0007596760.040
positive regulation of chronic inflammatory responseGO:000267840.040
regulation of defense response to virusGO:0050688180.040
negative regulation of intracellular signal transductionGO:19025321670.040
regulation of cellular amino acid metabolic processGO:000652150.040
positive regulation of osteoclast differentiationGO:0045672150.040
neuronal action potentialGO:0019228540.040
cerebral cortex cell migrationGO:0021795440.039
hyaluronan biosynthetic processGO:003021330.039
calcium ion transportGO:00068161590.039
Rat
membrane organizationGO:00610242450.039
alpha beta t cell proliferationGO:0046633210.039
response to granulocyte macrophage colony stimulating factorGO:009701230.038
cell chemotaxisGO:0060326810.038
regulation of hematopoietic stem cell migrationGO:200047110.038
multicellular organismal signalingGO:0035637910.038
myd88 independent toll like receptor signaling pathwayGO:000275630.038
regulation of epithelial cell proliferationGO:00506781410.038
signal transduction by p53 class mediatorGO:0072331510.038
cellular response to insulin stimulusGO:0032869780.038
regulation of regulatory t cell differentiationGO:004558970.038
regulation of mapk cascadeGO:00434082480.038
regulation of toll like receptor 4 signaling pathwayGO:003414340.038
response to acid chemicalGO:00011011110.038
actin cytoskeleton organizationGO:00300362200.038
protein kinase b signalingGO:0043491740.037
regulation of neutrophil chemotaxisGO:0090022140.037
cellular extravasationGO:0045123170.037
positive regulation of cell projection organizationGO:0031346950.037
regulation of protein transportGO:00512231630.037
branching morphogenesis of an epithelial tubeGO:00487541590.037
regulation of neuron projection developmentGO:00109751690.037
positive regulation of cytokine productionGO:00018191740.037
Mouse
response to oxidative stressGO:00069791230.036
cytokine productionGO:00018163190.036
dephosphorylationGO:00163111290.036
tyrosine phosphorylation of stat proteinGO:0007260230.036
Mouse Rat
polysaccharide biosynthetic processGO:0000271200.036
regulation of skeletal muscle fiber developmentGO:0048742360.036
cd4 positive alpha beta t cell lineage commitmentGO:004337360.036
phagocytosisGO:0006909660.036
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.036
regulation of cellular component sizeGO:00325351210.036
regulation of humoral immune responseGO:0002920220.036
hematopoietic stem cell migrationGO:003570110.036
regulation of protein complex assemblyGO:0043254830.036
protein secretionGO:00093061110.035
b cell activation involved in immune responseGO:0002312500.035
olfactory learningGO:000835520.035
cellular response to lipopolysaccharideGO:0071222770.035
Mouse
osteoclast developmentGO:003603590.035
muscle tissue developmentGO:00605373080.035
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.035
negative regulation of phosphorus metabolic processGO:00105631840.034
regulation of b cell differentiationGO:0045577230.034
regulation of homeostatic processGO:00328441820.034
protein localization to organelleGO:00333651850.034
Mouse
cd8 positive alpha beta t cell extravasationGO:003569730.033
interleukin 6 productionGO:0032635580.033
aminoglycan metabolic processGO:0006022340.033
neutrophil migrationGO:1990266370.033
response to alcoholGO:0097305480.033
Mouse
reactive nitrogen species metabolic processGO:200105700.033
negative regulation of regulatory t cell differentiationGO:004559020.033
interleukin 10 secretionGO:007260840.033
positive regulation of t cell extravasationGO:200040920.033
single organism cell adhesionGO:00986021560.033
regulation of tumor necrosis factor biosynthetic processGO:0042534100.033
positive regulation of protein kinase activityGO:00458601440.033
Mouse
positive regulation of alpha beta t cell differentiationGO:0046638280.033
positive regulation of kinase activityGO:00336741550.033
Mouse
cell divisionGO:00513011200.033
female sex differentiationGO:0046660840.033
positive regulation of protein phosphorylationGO:00019342420.032
Mouse
cell adhesionGO:00071553290.032
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.032
positive regulation of t cell proliferationGO:0042102520.032
Rat
negative regulation of interleukin 5 productionGO:003271440.032
pallium developmentGO:00215431200.032
regulation of monocyte chemotaxisGO:009002530.032
mammary gland lobule developmentGO:0061377220.032
interspecies interaction between organismsGO:0044419830.032
protein localization to nucleusGO:00345041210.032
Mouse
negative regulation of type 2 immune responseGO:000282980.031
purine ribonucleoside triphosphate metabolic processGO:00092052200.031
covalent chromatin modificationGO:00165691630.031
mucopolysaccharide metabolic processGO:1903510250.031
endocytosisGO:00068971680.031
regulation of growth of symbiont in hostGO:0044126190.031
regulation of leukocyte proliferationGO:00706631210.031
Rat
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.031
multicellular organism growthGO:00352641610.031
purine nucleoside triphosphate metabolic processGO:00091442260.031
response to insulinGO:00328681000.031
cell maturationGO:00484691270.030
antimicrobial peptide productionGO:000277520.030
regulation of hormone levelsGO:00108172110.030
mammary gland morphogenesisGO:0060443540.030
gamma delta t cell activationGO:0046629130.030
regulation of ion transportGO:00432692150.030
Rat
anatomical structure homeostasisGO:00602491450.030
mammary gland epithelium developmentGO:0061180650.029
Mouse
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.029
wound healingGO:00420601570.029
ameboidal type cell migrationGO:00016671280.029
Fly
chromatin organizationGO:00063252060.029
cellular response to lipidGO:00713961450.028
Mouse
somatic diversification of immune receptorsGO:0002200530.028
protein oligomerizationGO:0051259670.028
positive regulation of acute inflammatory responseGO:0002675160.028
regulation of t helper 1 cell differentiationGO:004562570.028
regulation of b cell mediated immunityGO:0002712370.028
intrinsic apoptotic signaling pathwayGO:00971931320.028
regulation of body fluid levelsGO:00508781620.028
cerebral cortex developmentGO:0021987860.028
regulation of production of molecular mediator of immune responseGO:0002700650.028
response to hypoxiaGO:0001666580.028
aromatic compound catabolic processGO:00194392860.028
multi multicellular organism processGO:00447061090.028
metal ion homeostasisGO:00550651890.027
Rat
female gamete generationGO:0007292740.027
Fly
regulation of interleukin 12 biosynthetic processGO:004507580.027
response to molecule of bacterial originGO:00022371430.027
Mouse
cd4 positive alpha beta t cell cytokine productionGO:003574340.027
regulation of exocytosisGO:0017157610.027
t helper 2 cell differentiationGO:0045064120.027
leukocyte activation involved in immune responseGO:00023661260.027
organic hydroxy compound metabolic processGO:19016152030.027
regulation of interleukin 2 productionGO:0032663280.027
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.027
cell junction organizationGO:0034330770.027
purine ribonucleotide metabolic processGO:00091502900.027
ensheathment of neuronsGO:0007272760.027
cytokine metabolic processGO:0042107710.027
peptidyl amino acid modificationGO:00181933360.027
stem cell developmentGO:00488642190.026
Fly
negative regulation of protein catabolic processGO:0042177360.026
regulation of type 2 immune responseGO:0002828180.026
circadian rhythmGO:00076231140.026
Fly
regulation of synaptic growth at neuromuscular junctionGO:000858240.026
humoral immune responseGO:0006959570.026
negative regulation of synapse assemblyGO:005196430.026
response to radiationGO:00093141650.026
detection of stimulus involved in sensory perceptionGO:0050906440.026
antigen receptor mediated signaling pathwayGO:0050851640.026
mitotic cell cycleGO:00002781950.026
neutrophil differentiationGO:003022330.026
reactive oxygen species metabolic processGO:0072593840.026
regulation of myotube differentiationGO:0010830620.026
acute inflammatory response to antigenic stimulusGO:0002438120.026
positive regulation of translational initiationGO:004594840.025
immunoglobulin productionGO:0002377730.025
neural tube developmentGO:00219151600.025
regulation of neutrophil migrationGO:1902622140.025
tissue homeostasisGO:00018941150.025
response to extracellular stimulusGO:00099911270.025
eosinophil activationGO:004330710.025
positive regulation of eosinophil migrationGO:200041820.025
negative regulation of multi organism processGO:0043901680.025
cellular chemical homeostasisGO:00550822150.024
Rat
hair cycleGO:0042633900.024
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.024
Mouse
t helper 1 cell differentiationGO:0045063130.024
regulation of kinase activityGO:00435492490.024
Mouse
regulation of cell divisionGO:0051302760.024
myelinationGO:0042552740.024
response to dsrnaGO:0043331300.024
interleukin 12 productionGO:0032615320.024
sequestering of calcium ionGO:0051208180.024
regulation of protein serine threonine kinase activityGO:00719001570.024
neural precursor cell proliferationGO:00613511210.024
regulation of vesicle mediated transportGO:00606271390.024
programmed necrotic cell deathGO:0097300280.024
regulation of interferon beta biosynthetic processGO:004535740.024
regulation of mitotic cell cycleGO:00073461260.024
antibacterial peptide productionGO:000277820.024
brown fat cell differentiationGO:0050873360.024
negative regulation of t helper 2 cell differentiationGO:004562940.024
regulation of homotypic cell cell adhesionGO:0034110130.024
aminoglycan biosynthetic processGO:0006023150.024
toll like receptor signaling pathwayGO:0002224380.024
positive regulation of reactive oxygen species metabolic processGO:2000379110.023
negative regulation of homeostatic processGO:0032845710.023
b cell apoptotic processGO:0001783190.023
regulation of nuclear divisionGO:0051783560.023
mrna transcription from rna polymerase ii promoterGO:004278940.023
regulation of cellular response to insulin stimulusGO:1900076300.023
branching involved in mammary gland duct morphogenesisGO:0060444270.023
regulation of chemotaxisGO:0050920530.023
cytoplasmic transportGO:00164822340.023
Mouse
rho protein signal transductionGO:0007266320.023
growth of symbiont in hostGO:0044117230.023
spermatogenesisGO:00072832840.023
axon ensheathmentGO:0008366760.023
regulation of antimicrobial peptide productionGO:000278410.023
regulation of carbohydrate metabolic processGO:0006109750.023
positive regulation of dendritic cell chemotaxisGO:200051010.023
regulation of inflammatory response to antigenic stimulusGO:0002861210.023
fat cell differentiationGO:00454441600.023
regulation of monocyte extravasationGO:200043720.023
detection of mechanical stimulus involved in sensory perception of painGO:005096640.022
somatic diversification of immunoglobulinsGO:0016445430.022

Jak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.099
disease of anatomical entityDOID:700.099
cancerDOID:16200.053
disease of cellular proliferationDOID:1456600.053
organ system cancerDOID:005068600.034
primary immunodeficiency diseaseDOID:61200.034
severe combined immunodeficiencyDOID:62700.034
combined t cell and b cell immunodeficiencyDOID:62800.034
nervous system diseaseDOID:86300.030