Mus musculus

41 known processes

Jak1

Janus kinase 1

(Aliases: C130039L05Rik,MGC37919,AA960307)

Jak1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of t cell activationGO:00508631700.780
Mouse
cellular ketone metabolic processGO:0042180840.592
negative regulation of cellular amino acid metabolic processGO:004576300.488
cytokine mediated signaling pathwayGO:00192211150.479
regulation of defense responseGO:00313472330.477
positive regulation of cell activationGO:00508671580.438
regulation of cell activationGO:00508652890.385
Mouse
peptidyl tyrosine modificationGO:00182121450.365
regulation of transferase activityGO:00513382630.356
Mouse
negative regulation of cellular amine metabolic processGO:003323910.333
regulation of insulin receptor signaling pathwayGO:0046626210.328
response to peptideGO:19016521360.318
Mouse
erythrocyte differentiationGO:0030218880.308
Mouse
regulation of inflammatory responseGO:00507271470.306
cellular amino acid metabolic processGO:00065201030.299
regulation of response to woundingGO:19030341890.298
regulation of lymphocyte activationGO:00512492400.286
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.283
mapk cascadeGO:00001652810.281
negative regulation of phosphorylationGO:00423261660.269
negative regulation of t cell activationGO:0050868650.265
Mouse
negative regulation of cellular response to insulin stimulusGO:1900077160.265
peptidyl amino acid modificationGO:00181933360.258
actin cytoskeleton organizationGO:00300362200.250
dephosphorylationGO:00163111290.247
response to peptide hormoneGO:00434341270.245
Mouse
positive regulation of lymphocyte activationGO:00512511400.241
chemotaxisGO:00069352470.240
negative regulation of protein phosphorylationGO:00019331260.238
myeloid cell differentiationGO:00300992330.235
Mouse
nucleoside catabolic processGO:00091642060.233
negative regulation of insulin receptor signaling pathwayGO:0046627140.228
immune response regulating signaling pathwayGO:00027641250.225
myeloid cell homeostasisGO:00022621140.201
Mouse
cellular response to peptide hormone stimulusGO:0071375920.201
Mouse
regulation of purine nucleotide metabolic processGO:19005421690.198
negative regulation of protein modification processGO:00314001630.193
regulation of t cell differentiationGO:0045580830.192
Mouse
adaptive immune responseGO:00022501550.191
Mouse
regulation of cellular amine metabolic processGO:0033238200.190
negative regulation of kinase activityGO:0033673810.190
cellular response to peptideGO:1901653920.179
Mouse
nucleoside phosphate metabolic processGO:00067533380.174
proteolysis involved in cellular protein catabolic processGO:00516031470.173
apical constrictionGO:000338340.170
Fly
regulation of leukocyte differentiationGO:19021051590.162
Mouse
negative regulation of phosphate metabolic processGO:00459361840.161
negative regulation of protein metabolic processGO:00512482820.161
Mouse
positive regulation of defense responseGO:00313491240.160
cellular response to cytokine stimulusGO:00713451890.158
cell adhesionGO:00071553290.158
cellular response to hormone stimulusGO:00328701500.154
Mouse
amine metabolic processGO:0009308450.151
cellular response to organonitrogen compoundGO:00714171450.150
Mouse
small gtpase mediated signal transductionGO:0007264970.144
regulation of hydrolase activityGO:00513362460.141
Mouse
inflammatory responseGO:00069542440.141
negative regulation of cellular protein metabolic processGO:00322692470.140
digestive tract developmentGO:00485651900.139
Fly
ribonucleoside metabolic processGO:00091192450.138
lymphocyte mediated immunityGO:00024491390.136
cellular response to growth factor stimulusGO:00713631970.136
regulation of organelle organizationGO:00330432890.130
t cell activationGO:00421102890.129
Zebrafish Mouse
positive regulation of t cell activationGO:00508701010.128
regulation of adaptive immune responseGO:0002819900.125
Mouse
nucleoside metabolic processGO:00091162460.124
tyrosine phosphorylation of stat1 proteinGO:004250830.123
positive regulation of purine nucleotide metabolic processGO:19005441140.122
regulation of cellular ketone metabolic processGO:0010565660.121
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.120
Mouse
positive regulation of response to woundingGO:1903036660.119
organonitrogen compound catabolic processGO:19015652640.118
spermatogenesisGO:00072832840.116
response to interleukin 15GO:007067230.114
Human
response to lipopolysaccharideGO:00324961280.114
Mouse
negative regulation of transferase activityGO:0051348850.114
regulation of mapk cascadeGO:00434082480.113
regulation of antigen receptor mediated signaling pathwayGO:0050854290.111
regulation of actin filament polymerizationGO:0030833380.110
negative regulation of cell proliferationGO:00082852960.110
Mouse
immune response activating cell surface receptor signaling pathwayGO:0002429720.110
digestive system developmentGO:00551232000.109
Fly
immune response activating signal transductionGO:00027571160.107
homeostasis of number of cellsGO:00488722100.107
Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.104
cytokine productionGO:00018163190.104
Mouse
actin filament organizationGO:00070151130.102
positive regulation of protein phosphorylationGO:00019342420.102
Mouse
ribonucleoside triphosphate metabolic processGO:00091992200.101
nucleoside phosphate catabolic processGO:19012922220.101
cellular amine metabolic processGO:0044106440.099
insulin receptor signaling pathwayGO:0008286490.098
purine ribonucleoside triphosphate catabolic processGO:00092071990.097
antigen receptor mediated signaling pathwayGO:0050851640.097
immune effector processGO:00022523210.096
Mouse Fly
organelle fissionGO:00482851700.096
regulation of actin cytoskeleton organizationGO:0032956840.096
axon guidanceGO:00074111410.095
negative regulation of immune effector processGO:0002698550.095
Mouse
t cell receptor signaling pathwayGO:0050852460.095
purine nucleotide metabolic processGO:00061633020.095
activation of janus kinase activityGO:004297620.095
Mouse
regulation of cellular amino acid metabolic processGO:000652150.093
ubiquitin dependent protein catabolic processGO:00065111290.093
negative regulation of intracellular signal transductionGO:19025321670.093
regulation of cellular component biogenesisGO:00440871810.092
purine nucleoside triphosphate metabolic processGO:00091442260.092
regulation of lymphocyte proliferationGO:00506701170.092
positive regulation of leukocyte proliferationGO:0070665730.091
positive regulation of gamma delta t cell differentiationGO:004558860.091
regulation of protein localizationGO:00328802310.090
guanosine containing compound catabolic processGO:19010691440.089
negative regulation of immune system processGO:00026832090.088
Mouse
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.088
response to organonitrogen compoundGO:00102432460.087
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.086
alpha beta t cell differentiationGO:0046632690.086
Mouse
long term memoryGO:0007616150.086
Fly
positive regulation of ras gtpase activityGO:0032320650.085
response to organic cyclic compoundGO:00140701980.085
Mouse
regulation of cellular catabolic processGO:00313292420.083
rho protein signal transductionGO:0007266320.083
cognitionGO:00508901490.083
Fly
regulation of leukocyte apoptotic processGO:2000106560.081
Mouse
regulation of cytoskeleton organizationGO:00514931220.081
activation of immune responseGO:00022531380.081
regulation of kinase activityGO:00435492490.080
Mouse
regulation of cytokine productionGO:00018172660.080
Mouse
regulation of cell motilityGO:20001452360.080
stem cell developmentGO:00488642190.080
Fly
germ cell developmentGO:00072811850.079
Fly
regulation of leukocyte mediated immunityGO:00027031040.078
Mouse
protein modification by small protein conjugation or removalGO:00706472070.078
response to growth factorGO:00708481980.077
male gamete generationGO:00482322850.077
macromolecule catabolic processGO:00090572810.077
positive regulation of nucleotide catabolic processGO:0030813880.077
negative regulation of t cell differentiationGO:0045581230.076
Mouse
glycosyl compound catabolic processGO:19016582060.076
protein processingGO:00164851630.076
Mouse
purine ribonucleotide metabolic processGO:00091502900.075
positive regulation of hydrolase activityGO:00513451480.075
Mouse
regulation of membrane potentialGO:00423911920.075
regulation of actin polymerization or depolymerizationGO:0008064450.074
purine nucleotide catabolic processGO:00061952110.073
cell fate commitmentGO:00451652100.072
cd4 positive alpha beta t cell activationGO:0035710450.072
Mouse
purine ribonucleoside metabolic processGO:00461282410.072
positive regulation of cell developmentGO:00107202370.072
ribose phosphate metabolic processGO:00196932910.071
actin polymerization or depolymerizationGO:0008154540.071
immunoglobulin productionGO:0002377730.070
membrane organizationGO:00610242450.070
b cell differentiationGO:0030183780.070
Mouse
regulation of t cell proliferationGO:0042129920.070
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.069
organic cyclic compound catabolic processGO:19013612950.069
t cell differentiationGO:00302171740.068
Zebrafish Mouse
positive regulation of nervous system developmentGO:00519622210.068
dna metabolic processGO:00062593030.068
regulation of cell adhesionGO:00301551540.068
nuclear divisionGO:00002801580.067
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.067
Mouse
maintenance of locationGO:0051235890.067
negative regulation of mapk cascadeGO:0043409650.067
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.066
cellular response to lipidGO:00713961450.066
Mouse
regulation of secretionGO:00510462740.066
regulation of actin filament lengthGO:0030832450.066
cellular response to organic cyclic compoundGO:0071407870.065
Mouse
ras protein signal transductionGO:0007265770.063
protein catabolic processGO:00301632210.063
negative regulation of cell activationGO:00508661110.063
Mouse
positive regulation of transferase activityGO:00513471670.062
Mouse
nucleotide metabolic processGO:00091173320.062
cellular protein complex assemblyGO:00436231160.062
modification dependent macromolecule catabolic processGO:00436321330.061
positive regulation of alpha beta t cell activationGO:0046635390.061
t cell proliferationGO:00420981200.061
negative regulation of molecular functionGO:00440922580.061
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.060
lymphocyte differentiationGO:00300982420.060
Zebrafish Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.059
Mouse
positive regulation of lymphocyte proliferationGO:0050671700.059
regulation of cd4 positive alpha beta t cell activationGO:2000514240.059
Mouse
cytoplasmic transportGO:00164822340.059
Mouse
regulation of response to cytokine stimulusGO:0060759230.058
positive regulation of mapk cascadeGO:00434101700.057
regulation of bindingGO:00510981110.057
Mouse
protein ubiquitinationGO:00165671710.057
regulation of b cell activationGO:0050864810.057
skeletal system developmentGO:00015013560.057
neuron projection guidanceGO:00974851410.057
purine containing compound catabolic processGO:00725232130.056
negative regulation of defense responseGO:0031348770.056
positive regulation of cellular catabolic processGO:00313311480.056
alpha beta t cell activationGO:0046631910.056
Mouse
positive regulation of t cell differentiationGO:0045582520.056
multicellular organism growthGO:00352641610.055
positive t cell selectionGO:0043368230.055
regulation of protein kinase activityGO:00458592320.055
Mouse
purine containing compound metabolic processGO:00725213110.055
muscle system processGO:00030121410.055
regulation of actin filament based processGO:0032970990.054
positive regulation of immune effector processGO:00026991070.053
regulation of gtp catabolic processGO:00331241130.053
regulation of system processGO:00440572000.053
meiotic nuclear divisionGO:00071261150.052
ribonucleoside triphosphate catabolic processGO:00092031990.052
locomotory behaviorGO:00076261950.052
Fly
regulation of leukocyte mediated cytotoxicityGO:0001910380.051
lateral inhibitionGO:004633110.051
gtp catabolic processGO:00061841430.051
ribonucleotide catabolic processGO:00092612080.051
epidermis developmentGO:00085441870.051
regulation of dendritic cell apoptotic processGO:200066830.051
Mouse
response to interleukin 4GO:0070670230.051
multicellular organismal signalingGO:0035637910.050
ribonucleoside catabolic processGO:00424542060.050
leukocyte activation involved in immune responseGO:00023661260.050
Mouse
protein modification by small protein conjugationGO:00324461870.050
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.050
Mouse
chromatin organizationGO:00063252060.050
negative regulation of leukocyte mediated immunityGO:0002704290.049
Mouse
cellular nitrogen compound catabolic processGO:00442702800.049
positive regulation of leukocyte differentiationGO:1902107860.048
establishment of organelle localizationGO:00516561220.048
cellular lipid metabolic processGO:00442553230.048
heart processGO:0003015940.047
negative regulation of cellular component organizationGO:00511291940.047
dna recombinationGO:0006310920.047
endomembrane system organizationGO:00102561470.047
regulation of immunoglobulin productionGO:0002637420.047
mast cell proliferationGO:007066240.046
regulation of body fluid levelsGO:00508781620.046
positive regulation of protein modification processGO:00314012990.046
Mouse
glucose homeostasisGO:00425931280.046
regulation of ras gtpase activityGO:0032318880.046
purine nucleoside metabolic processGO:00422782410.045
protein localization to organelleGO:00333651850.045
Mouse
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.045
regulation of cell projection organizationGO:00313442060.044
negative regulation of inflammatory responseGO:0050728610.044
leukocyte differentiationGO:00025213420.044
Zebrafish Mouse
regulation of cell cycle processGO:00105641600.044
neuron migrationGO:00017641220.044
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.043
oocyte anterior posterior axis specificationGO:000731420.043
immune response regulating cell surface receptor signaling pathwayGO:0002768800.043
memoryGO:0007613580.043
Fly
ribonucleotide metabolic processGO:00092592910.043
organ growthGO:00352651170.043
g protein coupled receptor signaling pathwayGO:00071862430.043
glycoprotein metabolic processGO:00091001160.043
Mouse
positive regulation of b cell activationGO:0050871490.043
cell divisionGO:00513011200.042
regulation of cellular response to stressGO:00801351590.042
regulation of nucleoside metabolic processGO:00091181300.042
actin filament bundle assemblyGO:0051017400.042
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.042
mesodermal cell migrationGO:000807840.041
negative regulation of neuron apoptotic processGO:0043524920.041
lipid localizationGO:00108761260.041
histone modificationGO:00165701590.041
purine ribonucleoside catabolic processGO:00461302050.041
midgut developmentGO:000749440.041
tyrosine phosphorylation of stat3 proteinGO:0042503120.041
Mouse
positive regulation of alpha beta t cell differentiationGO:0046638280.041
aromatic compound catabolic processGO:00194392860.041
t cell selectionGO:0045058340.040
methylationGO:00322591340.040
positive regulation of nucleotide metabolic processGO:00459811140.040
wnt signaling pathwayGO:00160551880.040
cellular macromolecule catabolic processGO:00442652060.040
neuron deathGO:00709971540.040
regulation of cell divisionGO:0051302760.040
regulation of secretion by cellGO:19035302490.040
tissue homeostasisGO:00018941150.040
protein autophosphorylationGO:0046777610.040
Mouse
regulation of mast cell activationGO:0033003210.040
regulation of ras protein signal transductionGO:00465781140.039
positive regulation of gtpase activityGO:0043547850.039
meiotic cell cycleGO:00513211220.039
interleukin 4 mediated signaling pathwayGO:003577120.039
actomyosin structure organizationGO:0031032560.039
response to granulocyte macrophage colony stimulating factorGO:009701230.039
isotype switchingGO:0045190360.039
heterocycle catabolic processGO:00467002800.039
positive regulation of protein kinase activityGO:00458601440.039
Mouse
regulation of cell migrationGO:00303342190.038
nucleotide catabolic processGO:00091662170.038
b cell activationGO:00421131610.038
Mouse
nitrogen compound transportGO:00717052710.038
plasma membrane organizationGO:0007009900.038
negative regulation of leukocyte differentiationGO:1902106510.037
Mouse
regulation of intracellular transportGO:00323861590.037
glial cell differentiationGO:00100011310.037
regulation of interleukin 2 productionGO:0032663280.037
positive regulation of inflammatory responseGO:0050729470.037
glycosyl compound metabolic processGO:19016572460.037
regulation of leukocyte proliferationGO:00706631210.037
positive regulation of leukocyte mediated immunityGO:0002705700.037
peptidyl tyrosine dephosphorylationGO:0035335230.036
thymic t cell selectionGO:0045061220.036
natural killer cell proliferationGO:000178730.036
positive regulation of cell deathGO:00109422240.036
Mouse
mitotic cell cycleGO:00002781950.036
lymphocyte homeostasisGO:0002260640.036
Mouse
carbohydrate homeostasisGO:00335001280.036
interleukin 2 mediated signaling pathwayGO:003811020.036
Human
regulation of cell cycleGO:00517262810.036
striated muscle tissue developmentGO:00147062930.036
gtp metabolic processGO:00460391440.036
stem cell differentiationGO:00488632680.035
Fly
regulation of myeloid leukocyte differentiationGO:0002761580.035
cellular response to transforming growth factor beta stimulusGO:0071560880.035
negative regulation of lymphocyte activationGO:0051250910.035
Mouse
skin developmentGO:00435882200.035
heart contractionGO:0060047930.035
regulation of sequence specific dna binding transcription factor activityGO:00510901060.035
regulation of lymphocyte mediated immunityGO:0002706840.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
response to amino acidGO:0043200370.034
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.034
microtubule based processGO:00070172360.034
hormone mediated signaling pathwayGO:0009755230.034
cellular response to interleukin 4GO:0071353210.034
modification dependent protein catabolic processGO:00199411330.034
innate immune responseGO:00450871570.034
interleukin 2 productionGO:0032623330.034
platelet derived growth factor receptor signaling pathwayGO:0048008320.034
gastrulationGO:00073691160.034
Fly
actin filament polymerizationGO:0030041440.033
cellular response to insulin stimulusGO:0032869780.033
metal ion homeostasisGO:00550651890.033
covalent chromatin modificationGO:00165691630.033
somatic diversification of immunoglobulinsGO:0016445430.033
positive thymic t cell selectionGO:0045059130.033
learning or memoryGO:00076111480.033
Fly
production of molecular mediator of immune responseGO:00024401030.033
Mouse
mitochondrion distributionGO:004831140.032
immunoglobulin mediated immune responseGO:0016064690.032
type i interferon signaling pathwayGO:0060337100.032
cytokinesisGO:0000910170.032
t cell homeostasisGO:0043029350.032
Mouse
regulation of establishment of protein localizationGO:00702011810.032
negative regulation of response to cytokine stimulusGO:006076190.032
regulation of lymphocyte differentiationGO:00456191070.032
Mouse
positive regulation of cytokine productionGO:00018191740.032
Mouse
regulation of production of molecular mediator of immune responseGO:0002700650.032
Mouse
cellular carbohydrate metabolic processGO:00442621190.032
positive regulation of lymphocyte differentiationGO:0045621610.031
regulation of cellular response to insulin stimulusGO:1900076300.031
muscle tissue developmentGO:00605373080.031
positive regulation of programmed cell deathGO:00430682180.031
Mouse
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.031
Mouse
leukocyte mediated cytotoxicityGO:0001909620.031
peptidyl tyrosine phosphorylationGO:00181081430.031
lateral line system developmentGO:004892510.031
regulation of dna recombinationGO:0000018340.031
interferon gamma mediated signaling pathwayGO:006033350.031
positive regulation of apoptotic signaling pathwayGO:2001235950.031
Mouse
t cell differentiation in thymusGO:0033077770.031
Zebrafish
positive regulation of dna templated transcription elongationGO:003278620.031
meiotic cell cycle processGO:1903046770.031
positive regulation of t cell proliferationGO:0042102520.030
anatomical structure homeostasisGO:00602491450.030
nucleoside monophosphate metabolic processGO:0009123850.030
single organism cell adhesionGO:00986021560.030
positive regulation of intracellular transportGO:0032388700.030
leukocyte proliferationGO:00706611720.030
carbohydrate derivative catabolic processGO:19011362310.030
organophosphate catabolic processGO:00464342320.030
cellular response to type i interferonGO:0071357100.030
regulation of mast cell proliferationGO:007066640.029
glycoprotein biosynthetic processGO:0009101890.029
Mouse
myeloid cell apoptotic processGO:0033028220.029
sensory perceptionGO:00076002450.029
cellular response to interleukin 6GO:007135490.029
positive regulation of neuron differentiationGO:00456661410.029
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.029
Mouse
carbohydrate metabolic processGO:00059752300.029
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.029
Mouse
atp catabolic processGO:0006200550.029
positive regulation of phosphatase activityGO:001092240.028
ribonucleoside monophosphate metabolic processGO:0009161800.028
positive regulation of secretionGO:00510471300.028
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.028
Mouse
cellular response to interleukin 15GO:007135020.028
Human
regulation of alpha beta t cell differentiationGO:0046637350.028
Mouse
regulation of cellular carbohydrate metabolic processGO:0010675750.028
somatic recombination of immunoglobulin gene segmentsGO:0016447420.028
neuron apoptotic processGO:00514021420.027
positive regulation of secretion by cellGO:19035321140.027
blood circulationGO:00080151950.027
regulation of myeloid cell differentiationGO:0045637960.027
tyrosine phosphorylation of stat5 proteinGO:004250690.027
Mouse
lymphocyte proliferationGO:00466511640.027
positive regulation of adaptive immune responseGO:0002821610.027
sensory organ morphogenesisGO:00905962420.026
Fly
formation of primary germ layerGO:0001704770.026
protein secretionGO:00093061110.026
bone developmentGO:00603481200.026
peptidyl serine modificationGO:0018209830.026
regulation of cytokine biosynthetic processGO:0042035590.026
regulation of alpha beta t cell activationGO:0046634530.026
Mouse
nucleoside triphosphate catabolic processGO:00091432050.026
myeloid leukocyte differentiationGO:00025731190.026
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.026
interleukin 6 mediated signaling pathwayGO:007010260.026
protein polyubiquitinationGO:0000209330.026
circulatory system processGO:00030131970.026
multicellular organismal homeostasisGO:00488711640.026
urogenital system developmentGO:00016552610.026
cellular response to molecule of bacterial originGO:0071219830.026
Mouse
spermatid differentiationGO:00485151150.026
cell activation involved in immune responseGO:00022631260.025
Mouse
regulation of nucleotide metabolic processGO:00061401690.025
hepatocyte growth factor receptor signaling pathwayGO:004801230.025
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.025
regulation of protein transportGO:00512231630.025
positive regulation of insulin secretionGO:0032024260.025
camera type eye developmentGO:00430102660.025
axonogenesisGO:00074092740.025
regulation of nucleotide catabolic processGO:00308111220.025
positive regulation of cellular amine metabolic processGO:003324050.025
oocyte constructionGO:000730820.025
regulation of lamellipodium assemblyGO:001059130.025
ossificationGO:00015032160.025
ribonucleoside monophosphate catabolic processGO:0009158570.025
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.025
cellular chemical homeostasisGO:00550822150.025
atp metabolic processGO:0046034750.024
regulation of anatomical structure sizeGO:00900661780.024
regulation of protein complex assemblyGO:0043254830.024
dendrite developmentGO:00163581150.024
wound healingGO:00420601570.024
regulation of neuron apoptotic processGO:00435231220.024
positive regulation of organelle organizationGO:00106381280.024
cd4 positive alpha beta t cell differentiationGO:0043367410.024
Mouse
positive regulation of hematopoietic stem cell migrationGO:200047310.024
proteasomal protein catabolic processGO:0010498980.024
regulation of map kinase activityGO:00434051200.024
cellular response to interferon gammaGO:0071346250.024
regionalizationGO:00030023370.023
Fly
generation of precursor metabolites and energyGO:00060911030.023
negative regulation of neuron deathGO:1901215980.023
tolerance induction to self antigenGO:000251340.023
cellular homeostasisGO:00197252400.023
response to oxidative stressGO:00069791230.023
leukocyte homeostasisGO:0001776790.023
Mouse
progesterone metabolic processGO:004244840.023
response to reactive oxygen speciesGO:0000302560.023
regulation of cell substrate adhesionGO:0010810730.023
chromatin modificationGO:00165681870.023
gland developmentGO:00487323300.023
Mouse Fly
nucleoside triphosphate metabolic processGO:00091412300.023
macromolecule methylationGO:00434141200.023
transforming growth factor beta receptor signaling pathwayGO:0007179710.022
regulation of protein bindingGO:0043393600.022
valine metabolic processGO:000657340.022
central nervous system neuron differentiationGO:00219531620.022
jnk cascadeGO:0007254720.022
purine ribonucleotide catabolic processGO:00091542080.022
regulation of cellular component sizeGO:00325351210.022
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.022
cellular response to abiotic stimulusGO:0071214560.022
connective tissue developmentGO:00614481790.022
digestive tract morphogenesisGO:00485461470.022
Fly
regulation of neuron differentiationGO:00456642810.022
negative regulation of cytokine productionGO:0001818840.022
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.022
opsonizationGO:000822830.022
regulation of chromosome organizationGO:0033044830.022
negative regulation of organelle organizationGO:0010639900.022
regulation of osteoblast differentiationGO:0045667670.022
multi multicellular organism processGO:00447061090.022
adherens junction organizationGO:0034332280.022
positive regulation of gtp catabolic processGO:0033126850.022
amide transportGO:00428861380.022
gamma delta t cell differentiationGO:0042492110.021
negative regulation of platelet derived growth factor receptor beta signaling pathwayGO:200058720.021
negative regulation of glycoprotein metabolic processGO:190301930.021
Mouse
endocytosisGO:00068971680.021
regulation of cell morphogenesis involved in differentiationGO:00107691510.021
negative regulation of t cell proliferationGO:0042130380.021
ventricular cardiac myofibril assemblyGO:005500530.021
mammary gland epithelium developmentGO:0061180650.021
Mouse
peptide secretionGO:00027901140.021

Jak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.057
connective tissue diseaseDOID:6500.054
disease of anatomical entityDOID:700.054
musculoskeletal system diseaseDOID:1700.054
bone diseaseDOID:008000100.043
organ system cancerDOID:005068600.034
cancerDOID:16200.034