Mus musculus

257 known processes

Pde4d

phosphodiesterase 4D, cAMP specific

(Aliases: Dpde3,9630011N22Rik)

Pde4d biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of ion transmembrane transportGO:00347651190.055
nucleotide metabolic processGO:00091173320.052
purine ribonucleotide metabolic processGO:00091502900.052
oxidation reduction processGO:00551143420.052
ras protein signal transductionGO:0007265770.052
transmembrane transportGO:00550854120.051
rho protein signal transductionGO:0007266320.050
organophosphate catabolic processGO:00464342320.050
macromolecule catabolic processGO:00090572810.048
regulation of cellular ketone metabolic processGO:0010565660.048
cell growth involved in cardiac muscle cell developmentGO:006104930.047
carbohydrate derivative catabolic processGO:19011362310.047
nucleoside phosphate catabolic processGO:19012922220.046
nucleoside metabolic processGO:00091162460.046
cardiac muscle cell contractionGO:008600370.046
nucleoside phosphate metabolic processGO:00067533380.046
habituationGO:004695930.045
ribonucleoside metabolic processGO:00091192450.045
small gtpase mediated signal transductionGO:0007264970.045
ribonucleotide metabolic processGO:00092592910.044
amine metabolic processGO:0009308450.044
Mouse
aromatic compound catabolic processGO:00194392860.043
nucleoside triphosphate metabolic processGO:00091412300.043
purine ribonucleoside metabolic processGO:00461282410.043
regulation of cellular amine metabolic processGO:0033238200.041
Mouse
glycosyl compound metabolic processGO:19016572460.041
ribonucleoside catabolic processGO:00424542060.040
mapk cascadeGO:00001652810.040
purine nucleotide metabolic processGO:00061633020.039
anatomical structure homeostasisGO:00602491450.038
cellular homeostasisGO:00197252400.038
nucleobase containing small molecule metabolic processGO:00550863520.038
purine ribonucleoside catabolic processGO:00461302050.038
cytokine productionGO:00018163190.038
Human
cellular ketone metabolic processGO:0042180840.038
gtp catabolic processGO:00061841430.037
regulation of protein localizationGO:00328802310.037
purine nucleoside metabolic processGO:00422782410.036
cellular nitrogen compound catabolic processGO:00442702800.036
organic cyclic compound catabolic processGO:19013612950.035
nucleoside catabolic processGO:00091642060.035
positive regulation of cell developmentGO:00107202370.035
multicellular organismal signalingGO:0035637910.035
purine nucleotide catabolic processGO:00061952110.035
response to organonitrogen compoundGO:00102432460.035
ribonucleoside triphosphate metabolic processGO:00091992200.034
purine nucleoside triphosphate metabolic processGO:00091442260.034
regulation of establishment of protein localizationGO:00702011810.034
synaptic transmissionGO:00072683290.034
Mouse Fly
ribonucleotide catabolic processGO:00092612080.034
purine containing compound metabolic processGO:00725213110.033
purine nucleoside catabolic processGO:00061522050.033
muscle tissue developmentGO:00605373080.033
cation transportGO:00068123990.033
glycosyl compound catabolic processGO:19016582060.033
cation transmembrane transportGO:00986552660.033
regulation of ion transportGO:00432692150.033
purine ribonucleoside triphosphate metabolic processGO:00092052200.032
negative regulation of phosphorus metabolic processGO:00105631840.031
axonogenesisGO:00074092740.031
Fly
purine nucleoside triphosphate catabolic processGO:00091462030.031
regulation of hydrolase activityGO:00513362460.031
negative regulation of protein metabolic processGO:00512482820.031
purine ribonucleotide catabolic processGO:00091542080.031
ion transmembrane transportGO:00342203610.031
actin filament based movementGO:0030048230.031
regulation of transmembrane transportGO:00347621280.031
response to organic cyclic compoundGO:00140701980.030
sensory perceptionGO:00076002450.030
Mouse
purine containing compound catabolic processGO:00725232130.030
regulation of cellular amino acid metabolic processGO:000652150.030
ribonucleoside triphosphate catabolic processGO:00092031990.030
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
positive regulation of cellular catabolic processGO:00313311480.029
regulation of renin secretion into blood streamGO:190013340.029
ribose phosphate metabolic processGO:00196932910.029
nucleoside triphosphate catabolic processGO:00091432050.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
positive regulation of transferase activityGO:00513471670.027
regulation of postsynaptic membrane potentialGO:0060078480.027
regulation of cell projection organizationGO:00313442060.027
cellular lipid metabolic processGO:00442553230.027
nucleotide catabolic processGO:00091662170.027
regulation of body fluid levelsGO:00508781620.027
regulation of nucleotide metabolic processGO:00061401690.026
spermatogenesisGO:00072832840.026
carbohydrate metabolic processGO:00059752300.026
cellular amino acid metabolic processGO:00065201030.026
apoptotic signaling pathwayGO:00971903060.026
nitrogen compound transportGO:00717052710.026
intracellular protein transportGO:00068862040.026
negative regulation of cellular component organizationGO:00511291940.026
membrane organizationGO:00610242450.025
response to radiationGO:00093141650.025
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.025
protein secretionGO:00093061110.025
adult behaviorGO:00305341350.025
physiological cardiac muscle hypertrophyGO:000330130.025
heterocycle catabolic processGO:00467002800.025
striated muscle contractionGO:0006941450.025
regulation of organelle organizationGO:00330432890.025
inorganic cation transmembrane transportGO:00986622070.025
peptidyl amino acid modificationGO:00181933360.025
protein catabolic processGO:00301632210.025
positive regulation of protein modification processGO:00314012990.024
cognitionGO:00508901490.024
Mouse Fly
protein modification by small protein conjugation or removalGO:00706472070.024
anion transportGO:00068201770.024
wound healingGO:00420601570.024
cytoplasmic transportGO:00164822340.024
regulation of defense responseGO:00313472330.024
organonitrogen compound biosynthetic processGO:19015661920.024
g protein coupled receptor signaling pathwayGO:00071862430.024
regulation of ras protein signal transductionGO:00465781140.024
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
cell type specific apoptotic processGO:00972852680.023
muscle cell differentiationGO:00426922610.023
regulation of secretion by cellGO:19035302490.023
regulation of secretionGO:00510462740.023
forebrain developmentGO:00309003020.023
carbohydrate derivative biosynthetic processGO:19011371830.023
regulation of long term synaptic potentiationGO:190027140.023
gtp metabolic processGO:00460391440.022
regulation of transporter activityGO:0032409570.022
regulation of apoptotic signaling pathwayGO:20012331970.022
regulation of nucleotide catabolic processGO:00308111220.022
regulation of protein transportGO:00512231630.022
positive regulation of purine nucleotide metabolic processGO:19005441140.022
positive regulation of programmed cell deathGO:00430682180.022
cellular amine metabolic processGO:0044106440.022
Mouse
regulation of transferase activityGO:00513382630.022
gland developmentGO:00487323300.022
positive regulation of gtpase activityGO:0043547850.022
metal ion homeostasisGO:00550651890.022
cation homeostasisGO:00550802120.021
regulation of purine nucleotide catabolic processGO:00331211220.021
striated muscle tissue developmentGO:00147062930.021
divalent inorganic cation transportGO:00725111780.021
physiological muscle hypertrophyGO:000329830.021
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.021
positive regulation of hydrolase activityGO:00513451480.021
action potentialGO:0001508780.021
organonitrogen compound catabolic processGO:19015652640.021
regulation of neuron differentiationGO:00456642810.021
negative regulation of molecular functionGO:00440922580.021
regulation of anatomical structure sizeGO:00900661780.021
guanosine containing compound catabolic processGO:19010691440.021
regulation of cytokine productionGO:00018172660.021
Human
actin filament organizationGO:00070151130.021
regulation of purine nucleotide metabolic processGO:19005421690.021
regulation of mapk cascadeGO:00434082480.021
circulatory system processGO:00030131970.021
protein localization to membraneGO:00726571080.021
positive regulation of neuron differentiationGO:00456661410.021
cellular ion homeostasisGO:00068731650.020
positive regulation of kinase activityGO:00336741550.020
cellular macromolecule catabolic processGO:00442652060.020
positive regulation of nucleotide metabolic processGO:00459811140.020
cellular divalent inorganic cation homeostasisGO:00725031270.020
establishment of protein localization to organelleGO:00725941180.020
guanosine containing compound metabolic processGO:19010681440.020
locomotory behaviorGO:00076261950.020
Mouse
ossificationGO:00015032160.020
regulation of cellular catabolic processGO:00313292420.019
nuclear transportGO:00511691390.019
monocarboxylic acid metabolic processGO:00327871910.019
regulation of proteolysisGO:00301621640.019
regulation of gtp catabolic processGO:00331241130.019
positive regulation of nervous system developmentGO:00519622210.019
positive regulation of secretionGO:00510471300.019
regulation of hormone levelsGO:00108172110.019
transmission of nerve impulseGO:0019226760.019
cellular metal ion homeostasisGO:00068751510.019
positive regulation of ion transportGO:0043270650.019
muscle contractionGO:00069361010.019
cell adhesionGO:00071553290.018
regulation of membrane potentialGO:00423911920.018
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711330.018
nucleocytoplasmic transportGO:00069131390.018
peptide transportGO:00158331330.018
protein modification by small protein conjugationGO:00324461870.018
positive regulation of nucleoside metabolic processGO:0045979910.018
cellular protein complex assemblyGO:00436231160.018
protein localization to organelleGO:00333651850.018
multicellular organismal response to stressGO:0033555620.018
protein localization to nucleusGO:00345041210.018
regulation of cell motilityGO:20001452360.018
cellular chemical homeostasisGO:00550822150.018
positive regulation of dendrite developmentGO:1900006210.018
actin cytoskeleton organizationGO:00300362200.018
positive regulation of gtp catabolic processGO:0033126850.018
multicellular organism growthGO:00352641610.018
leukocyte differentiationGO:00025213420.018
protein maturationGO:00516041760.018
regulation of cell activationGO:00508652890.018
organic hydroxy compound metabolic processGO:19016152030.018
Mouse
dna metabolic processGO:00062593030.018
posttranscriptional regulation of gene expressionGO:00106081550.018
immune effector processGO:00022523210.018
neuronal action potentialGO:0019228540.018
positive regulation of cell deathGO:00109422240.018
fat cell differentiationGO:00454441600.018
regulation of cellular component biogenesisGO:00440871810.018
chemotaxisGO:00069352470.018
learning or memoryGO:00076111480.018
Mouse Fly
central nervous system neuron differentiationGO:00219531620.018
endocytosisGO:00068971680.017
feeding behaviorGO:0007631620.017
Fly
cardiac muscle contractionGO:0060048320.017
negative regulation of organelle organizationGO:0010639900.017
protein targetingGO:00066051430.017
regulation of kinase activityGO:00435492490.017
positive regulation of apoptotic processGO:00430652170.017
protein ubiquitinationGO:00165671710.017
positive regulation of cellular amine metabolic processGO:003324050.017
negative regulation of intracellular signal transductionGO:19025321670.017
positive regulation of protein phosphorylationGO:00019342420.017
fertilizationGO:00095661270.017
positive regulation of mapk cascadeGO:00434101700.017
telencephalon developmentGO:00215371860.017
cellular calcium ion homeostasisGO:00068741190.017
skeletal muscle organ developmentGO:00605381630.017
regulation of cell morphogenesis involved in differentiationGO:00107691510.016
response to nutrient levelsGO:00316671090.016
negative regulation of serotonin secretionGO:001406320.016
maintenance of locationGO:0051235890.016
epithelial tube morphogenesisGO:00605623030.016
regulation of ras gtpase activityGO:0032318880.016
lipid homeostasisGO:0055088630.016
organic hydroxy compound transportGO:0015850930.016
positive regulation of cytokine productionGO:00018191740.016
Human
regulation of actin filament based processGO:0032970990.016
positive regulation of purine nucleotide catabolic processGO:0033123880.016
long term synaptic potentiationGO:0060291250.016
regulation of nucleoside metabolic processGO:00091181300.016
microtubule based processGO:00070172360.016
adult locomotory behaviorGO:0008344910.016
positive regulation of nucleotide catabolic processGO:0030813880.016
epithelial cell developmentGO:00020641590.016
cellular response to organonitrogen compoundGO:00714171450.016
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.016
regulation of feeding behaviorGO:006025930.016
endomembrane system organizationGO:00102561470.016
organelle assemblyGO:00709251770.016
energy derivation by oxidation of organic compoundsGO:0015980770.016
neuron neuron synaptic transmissionGO:0007270690.015
glucose homeostasisGO:00425931280.015
regulation of actin cytoskeleton organizationGO:0032956840.015
regulation of synaptic plasticityGO:0048167870.015
male gamete generationGO:00482322850.015
regulation of blood pressureGO:0008217930.015
tissue homeostasisGO:00018941150.015
generation of precursor metabolites and energyGO:00060911030.015
defecationGO:003042110.015
regulation of cytoskeleton organizationGO:00514931220.015
regulation of serotonin secretionGO:001406230.015
renal system developmentGO:00720012250.015
peptide hormone secretionGO:00300721090.015
divalent inorganic cation homeostasisGO:00725071380.015
tissue remodelingGO:00487711020.015
carbohydrate homeostasisGO:00335001280.015
cellular response to hormone stimulusGO:00328701500.015
multicellular organismal homeostasisGO:00488711640.015
skeletal system developmentGO:00015013560.015
mitochondrion organizationGO:00070051340.015
protein processingGO:00164851630.014
regulation of metal ion transportGO:00109591060.014
positive regulation of ion transmembrane transporter activityGO:0032414150.014
protein importGO:00170381010.014
response to light stimulusGO:00094161350.014
Mouse
organophosphate biosynthetic processGO:00904071220.014
response to extracellular stimulusGO:00099911270.014
response to molecule of bacterial originGO:00022371430.014
positive regulation of protein kinase activityGO:00458601440.014
respiratory system developmentGO:00605411900.014
epithelial tube formationGO:00721751300.014
developmental growth involved in morphogenesisGO:00605601380.014
Fly
positive regulation of camp mediated signalingGO:004395030.014
memoryGO:0007613580.014
Fly
oocyte constructionGO:000730820.014
hematopoietic progenitor cell differentiationGO:00022441430.014
embryonic organ morphogenesisGO:00485622760.014
cytosolic calcium ion homeostasisGO:0051480700.014
blood circulationGO:00080151950.014
operant conditioningGO:003510620.014
muscle system processGO:00030121410.014
nuclear importGO:0051170950.014
respiratory tube developmentGO:00303231670.014
positive regulation of protein transportGO:0051222930.014
regulation of homeostatic processGO:00328441820.014
heart morphogenesisGO:00030071780.014
negative regulation of cellular amine metabolic processGO:003323910.014
positive regulation of ras gtpase activityGO:0032320650.013
regulation of systemic arterial blood pressureGO:0003073610.013
inorganic ion transmembrane transportGO:00986602340.013
single organism nuclear importGO:1902593950.013
regulation of system processGO:00440572000.013
cellular component assembly involved in morphogenesisGO:00109271390.013
negative regulation of phosphate metabolic processGO:00459361840.013
cellular carbohydrate metabolic processGO:00442621190.013
multi organism behaviorGO:0051705620.013
homeostasis of number of cellsGO:00488722100.013
Mouse
carbohydrate transportGO:0008643620.013
synapse organizationGO:00508081250.013
nucleotide biosynthetic processGO:0009165780.013
digestive system developmentGO:00551232000.013
leukocyte mediated immunityGO:00024431740.013
inflammatory responseGO:00069542440.013
regulation of ossificationGO:00302781120.013
t cell activationGO:00421102890.013
epithelial cell proliferationGO:00506731740.013
glucan metabolic processGO:0044042320.013
polysaccharide metabolic processGO:0005976390.013
dendrite developmentGO:00163581150.013
learningGO:0007612980.013
Mouse Fly
organic anion transportGO:00157111370.013
meiotic nuclear divisionGO:00071261150.013
calcium ion homeostasisGO:00550741270.013
neuron deathGO:00709971540.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
lung developmentGO:00303241640.013
exocytosisGO:00068871210.013
positive regulation of cell motilityGO:20001471160.013
subpallium developmentGO:0021544200.012
negative regulation of protein modification processGO:00314001630.012
urogenital system developmentGO:00016552610.012
positive regulation of cell projection organizationGO:0031346950.012
negative regulation of secretionGO:0051048610.012
neuromuscular processGO:0050905990.012
positive regulation of heart rate by epinephrine norepinephrineGO:000199640.012
striated muscle cell developmentGO:00550021250.012
regulation of cellular response to stressGO:00801351590.012
rhythmic processGO:00485111740.012
organelle fissionGO:00482851700.012
cellular response to lipidGO:00713961450.012
response to temperature stimulusGO:0009266550.012
Fly
behavioral fear responseGO:0001662280.012
negative regulation of cell proliferationGO:00082852960.012
regulation of cell cycleGO:00517262810.012
gliogenesisGO:00420631410.012
positive regulation of secretion by cellGO:19035321140.012
myeloid cell differentiationGO:00300992330.012
erk1 and erk2 cascadeGO:0070371770.012
reactive oxygen species metabolic processGO:0072593840.012
negative regulation of secretion by cellGO:1903531540.012
plasma membrane organizationGO:0007009900.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
amide transportGO:00428861380.012
glial cell differentiationGO:00100011310.012
regulation of protein secretionGO:0050708820.012
positive regulation of neuron projection developmentGO:0010976790.012
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199730.012
stem cell differentiationGO:00488632680.012
rna processingGO:00063961050.012
positive regulation of transmembrane transportGO:0034764290.012
morphogenesis of embryonic epitheliumGO:00163311590.012
peptide secretionGO:00027901140.012
meiotic cell cycleGO:00513211220.012
axon guidanceGO:00074111410.012
regulation of blood circulationGO:1903522930.012
positive regulation of cellular component biogenesisGO:0044089940.012
digestive tract developmentGO:00485651900.012
cellular polysaccharide metabolic processGO:0044264380.012
cell maturationGO:00484691270.012
glycoprotein biosynthetic processGO:0009101890.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
regulation of intracellular transportGO:00323861590.012
regulation of muscle tissue developmentGO:1901861970.011
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148240.011
muscle adaptationGO:0043500390.011
myeloid leukocyte differentiationGO:00025731190.011
lipid biosynthetic processGO:00086101790.011
regulation of fat cell differentiationGO:0045598810.011
regulation of cell migrationGO:00303342190.011
response to lipopolysaccharideGO:00324961280.011
stem cell developmentGO:00488642190.011
mrna metabolic processGO:0016071840.011
angiogenesisGO:00015252010.011
hexose transportGO:0008645560.011
cyclic nucleotide metabolic processGO:0009187590.011
sequestering of metal ionGO:0051238190.011
protein import into nucleusGO:0006606950.011
calcium ion transportGO:00068161590.011
purine nucleotide biosynthetic processGO:0006164650.011
adult walking behaviorGO:0007628410.011
multi multicellular organism processGO:00447061090.011
cytokine secretionGO:0050663720.011
cardiocyte differentiationGO:0035051870.011
cellular response to cytokine stimulusGO:00713451890.011
cellular response to organic cyclic compoundGO:0071407870.011
digestive tract morphogenesisGO:00485461470.011
phenol containing compound metabolic processGO:0018958600.011
Mouse
placenta developmentGO:00018901400.011
striated muscle myosin thick filament assemblyGO:007168810.011
olfactory learningGO:000835520.011
cellular protein catabolic processGO:00442571550.011
anion transmembrane transportGO:0098656710.011
kidney developmentGO:00018222130.011
positive regulation of glycolytic processGO:004582140.011
neuron apoptotic processGO:00514021420.011
regulation of protein processingGO:0070613960.011
monosaccharide transportGO:0015749580.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
embryonic epithelial tube formationGO:00018381300.011
hormone secretionGO:00468791280.011
divalent metal ion transportGO:00708381720.011
small molecule biosynthetic processGO:00442831320.011
engulfment of apoptotic cellGO:004365230.011
organelle localizationGO:00516401790.011
defense response to other organismGO:00985421970.011
regulation of cellular component sizeGO:00325351210.011
sequestering of calcium ionGO:0051208180.011
regulation of muscle contractionGO:0006937490.011
cellular response to dna damage stimulusGO:00069742070.010
nuclear divisionGO:00002801580.010
male genitalia morphogenesisGO:004880840.010
chromatin modificationGO:00165681870.010
carbohydrate catabolic processGO:0016052320.010
skeletal myofibril assemblyGO:001486640.010
response to growth factorGO:00708481980.010
response to acid chemicalGO:00011011110.010
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.010
camera type eye developmentGO:00430102660.010
regulation of protein maturationGO:1903317960.010
heart processGO:0003015940.010
cellular glucan metabolic processGO:0006073320.010
regulation of neurotransmitter levelsGO:0001505870.010
Mouse
cell activation involved in immune responseGO:00022631260.010
activation of adenylate cyclase activityGO:000719040.010
vesicle localizationGO:0051648860.010
purine ribonucleotide biosynthetic processGO:0009152590.010
neuromuscular process controlling balanceGO:0050885590.010
cell growthGO:00160491300.010
Fly
epithelial cell morphogenesisGO:0003382410.010
regulation of protein kinase activityGO:00458592320.010
regulation of neuron projection developmentGO:00109751690.010
regulation of protein serine threonine kinase activityGO:00719001570.010
regulation of response to woundingGO:19030341890.010

Pde4d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
Human
central nervous system diseaseDOID:33100.018
musculoskeletal system diseaseDOID:1700.016
Human
neurodegenerative diseaseDOID:128900.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013
immune system diseaseDOID:291400.012
cardiovascular system diseaseDOID:128700.012
hematopoietic system diseaseDOID:7400.011
disease of mental healthDOID:15000.010