Mus musculus

87 known processes

Skp2

S-phase kinase-associated protein 2 (p45)

(Aliases: FBXL1,MGC102075,MGC116668)

Skp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycleGO:00517262810.428
cellular response to dna damage stimulusGO:00069742070.325
nuclear divisionGO:00002801580.302
regulation of cell cycle processGO:00105641600.238
dna metabolic processGO:00062593030.197
organelle fissionGO:00482851700.185
response to radiationGO:00093141650.176
regulation of mitotic cell cycleGO:00073461260.148
mitotic cell cycle processGO:19030471590.141
germ cell developmentGO:00072811850.135
macromolecule catabolic processGO:00090572810.126
cellular macromolecule catabolic processGO:00442652060.118
positive regulation of programmed cell deathGO:00430682180.113
negative regulation of cell cycleGO:00457861230.106
meiotic nuclear divisionGO:00071261150.103
negative regulation of cell cycle phase transitionGO:1901988480.099
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.099
intrinsic apoptotic signaling pathwayGO:00971931320.099
meiotic cell cycleGO:00513211220.095
regulation of mitotic cell cycle phase transitionGO:1901990730.090
positive regulation of apoptotic processGO:00430652170.089
mitotic nuclear divisionGO:0007067480.087
ubiquitin dependent protein catabolic processGO:00065111290.085
cell cycle g1 s phase transitionGO:0044843570.079
positive regulation of cell deathGO:00109422240.065
nucleocytoplasmic transportGO:00069131390.064
mitotic cell cycleGO:00002781950.062
cellular response to organonitrogen compoundGO:00714171450.062
dna endoreduplicationGO:004202340.061
negative regulation of cell cycle processGO:0010948690.060
apoptotic signaling pathwayGO:00971903060.060
negative regulation of mitotic cell cycle phase transitionGO:1901991450.059
regulation of cell cycle phase transitionGO:1901987770.058
negative regulation of ubiquitin protein transferase activityGO:005144430.052
regulation of cytoplasmic transportGO:19036491120.051
oxidation reduction processGO:00551143420.050
protein localization to nucleusGO:00345041210.050
dna repairGO:00062811070.048
negative regulation of cellular protein metabolic processGO:00322692470.047
b cell activationGO:00421131610.046
regulation of cellular catabolic processGO:00313292420.045
regulation of proteolysisGO:00301621640.045
cytoplasmic transportGO:00164822340.044
nuclear transportGO:00511691390.043
regulation of transferase activityGO:00513382630.043
cell fate commitmentGO:00451652100.042
membrane organizationGO:00610242450.041
dna dependent dna replicationGO:0006261240.040
chromatin modificationGO:00165681870.039
nucleoside metabolic processGO:00091162460.038
regulation of g1 s transition of mitotic cell cycleGO:2000045350.038
response to light stimulusGO:00094161350.038
regulation of intracellular transportGO:00323861590.038
proteasomal protein catabolic processGO:0010498980.038
regulation of cell cycle g1 s phase transitionGO:1902806350.037
cell cycle checkpointGO:0000075470.036
regulation of cell divisionGO:0051302760.036
male gamete generationGO:00482322850.036
nucleotide metabolic processGO:00091173320.036
gonad developmentGO:00084061410.035
cellular protein complex assemblyGO:00436231160.035
regulation of nucleocytoplasmic transportGO:0046822730.035
intracellular protein transportGO:00068862040.034
nucleobase containing small molecule metabolic processGO:00550863520.034
posttranscriptional regulation of gene expressionGO:00106081550.034
female gamete generationGO:0007292740.034
g1 s transition of mitotic cell cycleGO:0000082570.034
methylationGO:00322591340.033
production of molecular mediator of immune responseGO:00024401030.033
covalent chromatin modificationGO:00165691630.033
histone modificationGO:00165701590.032
response to organic cyclic compoundGO:00140701980.032
regulation of cellular protein catabolic processGO:1903362610.032
protein ubiquitinationGO:00165671710.032
chromosome segregationGO:0007059480.032
negative regulation of ligase activityGO:005135230.031
nitrogen compound transportGO:00717052710.031
microtubule based processGO:00070172360.031
protein methylationGO:0006479810.030
negative regulation of protein metabolic processGO:00512482820.030
organophosphate biosynthetic processGO:00904071220.030
neuroblast differentiationGO:001401620.030
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.030
nucleoside phosphate metabolic processGO:00067533380.029
heterocycle catabolic processGO:00467002800.029
peptidyl amino acid modificationGO:00181933360.029
regulation of mrna stabilityGO:0043488230.029
cell type specific apoptotic processGO:00972852680.029
somatic diversification of immune receptors via somatic mutationGO:000256680.028
cellular amine metabolic processGO:0044106440.028
response to organonitrogen compoundGO:00102432460.028
purine nucleoside metabolic processGO:00422782410.027
protein targetingGO:00066051430.027
protein catabolic processGO:00301632210.027
positive regulation of cellular catabolic processGO:00313311480.027
negative regulation of cell proliferationGO:00082852960.027
hematopoietic progenitor cell differentiationGO:00022441430.027
somatic recombination of immunoglobulin gene segmentsGO:0016447420.026
negative regulation of mitotic cell cycleGO:0045930580.026
macromolecule methylationGO:00434141200.026
regulation of protein catabolic processGO:00421761080.025
purine nucleoside triphosphate metabolic processGO:00091442260.025
cell divisionGO:00513011200.025
cellular protein catabolic processGO:00442571550.024
recombinational repairGO:0000725210.024
aromatic compound catabolic processGO:00194392860.024
spermatid developmentGO:00072861080.024
regulation of anatomical structure sizeGO:00900661780.024
regulation of establishment of protein localizationGO:00702011810.024
circulatory system processGO:00030131970.024
ribonucleoside triphosphate catabolic processGO:00092031990.023
regulation of lymphocyte activationGO:00512492400.023
mitotic sister chromatid segregationGO:0000070140.023
spermatogenesisGO:00072832840.023
nucleoside catabolic processGO:00091642060.023
proteolysis involved in cellular protein catabolic processGO:00516031470.023
protein modification by small protein conjugation or removalGO:00706472070.023
dna replicationGO:0006260520.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
protein maturationGO:00516041760.022
response to inorganic substanceGO:0010035960.022
nucleoside phosphate biosynthetic processGO:1901293790.022
protein importGO:00170381010.022
regulation of cellular amino acid metabolic processGO:000652150.022
positive regulation of mitotic cell cycleGO:0045931410.022
cellular amino acid metabolic processGO:00065201030.022
sister chromatid segregationGO:0000819200.021
modification dependent macromolecule catabolic processGO:00436321330.021
leukocyte activation involved in immune responseGO:00023661260.021
blood circulationGO:00080151950.021
mitochondrial genome maintenanceGO:0000002150.021
dna recombinationGO:0006310920.021
regulation of organelle organizationGO:00330432890.021
regulation of transcription by chromatin organizationGO:003440100.021
positive regulation of cell cycle phase transitionGO:1901989170.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
engulfment of apoptotic cellGO:004365230.020
regulation of cellular amine metabolic processGO:0033238200.020
regulation of intracellular protein transportGO:0033157820.020
purine ribonucleoside metabolic processGO:00461282410.020
regulation of protein transportGO:00512231630.019
regulation of cellular response to stressGO:00801351590.019
response to acid chemicalGO:00011011110.019
cellular response to hormone stimulusGO:00328701500.019
carbohydrate derivative biosynthetic processGO:19011371830.019
regulation of protein kinase activityGO:00458592320.019
protein oligomerizationGO:0051259670.019
negative regulation of cellular component organizationGO:00511291940.019
regulation of chromosome segregationGO:0051983210.019
monocarboxylic acid metabolic processGO:00327871910.019
regulation of nuclear divisionGO:0051783560.019
somatic cell dna recombinationGO:0016444510.019
somatic diversification of immunoglobulinsGO:0016445430.019
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.019
somatic diversification of immune receptorsGO:0002200530.019
myeloid cell differentiationGO:00300992330.019
regulation of circadian rhythmGO:0042752580.018
purine ribonucleoside triphosphate catabolic processGO:00092071990.018
purine nucleotide catabolic processGO:00061952110.018
muscle system processGO:00030121410.018
cell maturationGO:00484691270.018
cell activation involved in immune responseGO:00022631260.018
chromosome separationGO:0051304140.018
organonitrogen compound biosynthetic processGO:19015661920.018
negative regulation of protein modification processGO:00314001630.018
regionalizationGO:00030023370.018
protein modification by small protein conjugationGO:00324461870.018
regulation of membrane potentialGO:00423911920.018
regulation of proteasomal protein catabolic processGO:0061136460.018
regulation of protein modification by small protein conjugation or removalGO:1903320570.018
purine ribonucleotide metabolic processGO:00091502900.017
regulation of protein processingGO:0070613960.017
cellular component assembly involved in morphogenesisGO:00109271390.017
skeletal system developmentGO:00015013560.017
dna hypermethylationGO:004402630.017
rhythmic processGO:00485111740.017
ribose phosphate metabolic processGO:00196932910.017
intracellular mrna localizationGO:000829840.017
lymphocyte mediated immunityGO:00024491390.017
histone lysine methylationGO:0034968500.017
histone methylationGO:0016571710.017
rna processingGO:00063961050.017
isotype switchingGO:0045190360.017
male meiosis iGO:0007141160.016
glycosyl compound metabolic processGO:19016572460.016
multicellular organismal signalingGO:0035637910.016
protein polymerizationGO:0051258570.016
carbohydrate derivative catabolic processGO:19011362310.016
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.016
dna modificationGO:0006304500.016
positive regulation of proteolysisGO:0045862850.016
chromatin organizationGO:00063252060.016
cellular nitrogen compound catabolic processGO:00442702800.016
nuclear dna replicationGO:003326030.016
organic cyclic compound catabolic processGO:19013612950.016
organophosphate catabolic processGO:00464342320.015
positive regulation of cellular amine metabolic processGO:003324050.015
regulation of meiotic cell cycleGO:0051445340.015
regulation of rna stabilityGO:0043487260.015
purine nucleotide metabolic processGO:00061633020.015
protein heterotetramerizationGO:005129040.015
negative regulation of protein dephosphorylationGO:003530820.015
mrna splicing via spliceosomeGO:0000398430.015
ribonucleotide catabolic processGO:00092612080.015
mrna metabolic processGO:0016071840.015
meiotic cell cycle processGO:1903046770.015
regulation of cell activationGO:00508652890.015
purine ribonucleotide catabolic processGO:00091542080.015
b cell mediated immunityGO:0019724710.015
amine metabolic processGO:0009308450.015
positive regulation of cell cycleGO:0045787920.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.014
nucleotide catabolic processGO:00091662170.014
regulation of hydrolase activityGO:00513362460.014
positive regulation of protein modification processGO:00314012990.014
cellular response to radiationGO:0071478280.014
regulation of protein localizationGO:00328802310.014
positive regulation of hydrolase activityGO:00513451480.014
spermatid differentiationGO:00485151150.014
rna splicing via transesterification reactionsGO:0000375430.014
cellular ketone metabolic processGO:0042180840.014
regulation of chromatin silencingGO:003193520.014
microtubule cytoskeleton organizationGO:00002261570.014
single organism nuclear importGO:1902593950.014
protein localization to organelleGO:00333651850.014
protein import into nucleusGO:0006606950.014
small molecule biosynthetic processGO:00442831320.014
mitochondrion organizationGO:00070051340.014
cellularizationGO:000734910.014
transmission of nerve impulseGO:0019226760.014
maintenance of locationGO:0051235890.014
purine containing compound catabolic processGO:00725232130.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
cellular response to organic cyclic compoundGO:0071407870.013
negative regulation of cell divisionGO:0051782240.013
small gtpase mediated signal transductionGO:0007264970.013
regulation of cellular ketone metabolic processGO:0010565660.013
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.013
negative regulation of molecular functionGO:00440922580.013
compound eye developmentGO:004874910.013
immune effector processGO:00022523210.013
deoxyribonucleotide metabolic processGO:0009262140.013
regulation of cell cycle checkpointGO:190197690.013
striated muscle myosin thick filament assemblyGO:007168810.013
endocytosisGO:00068971680.013
organonitrogen compound catabolic processGO:19015652640.013
negative regulation of protein processingGO:0010955790.013
urogenital system developmentGO:00016552610.013
positive regulation of cytoplasmic transportGO:1903651400.013
regulation of system processGO:00440572000.013
epithelial tube morphogenesisGO:00605623030.013
positive regulation of cell cycle processGO:0090068610.013
gene silencingGO:0016458380.013
positive regulation of intracellular transportGO:0032388700.012
alpha amino acid metabolic processGO:1901605590.012
nucleotide biosynthetic processGO:0009165780.012
cell adhesionGO:00071553290.012
nucleus organizationGO:0006997450.012
organic hydroxy compound metabolic processGO:19016152030.012
establishment of protein localization to organelleGO:00725941180.012
regulation of kinase activityGO:00435492490.012
negative regulation of intracellular signal transductionGO:19025321670.012
regulation of cellular component biogenesisGO:00440871810.012
regulation of nucleotide metabolic processGO:00061401690.012
response to uvGO:0009411440.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
action potentialGO:0001508780.012
ribonucleotide metabolic processGO:00092592910.012
innate immune responseGO:00450871570.012
ras protein signal transductionGO:0007265770.012
positive regulation of cell developmentGO:00107202370.012
antimicrobial peptide biosynthetic processGO:000277720.012
nuclear importGO:0051170950.012
immunoglobulin productionGO:0002377730.012
double strand break repairGO:0006302480.012
regulation of apoptotic signaling pathwayGO:20012331970.012
response to growth factorGO:00708481980.012
protein processingGO:00164851630.012
connective tissue developmentGO:00614481790.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
cellular response to acid chemicalGO:0071229680.011
adaptive immune responseGO:00022501550.011
heterochromatin organizationGO:007082840.011
immunoglobulin mediated immune responseGO:0016064690.011
leukocyte proliferationGO:00706611720.011
lipid biosynthetic processGO:00086101790.011
regulation of cell shapeGO:0008360390.011
lymphocyte proliferationGO:00466511640.011
fatty acid metabolic processGO:00066311210.011
cellular lipid metabolic processGO:00442553230.011
neuroblast fate determinationGO:000740010.011
positive regulation of cellular component biogenesisGO:0044089940.011
purine containing compound metabolic processGO:00725213110.011
dna catabolic process endonucleolyticGO:0000737150.011
cellular response to lipidGO:00713961450.011
development of primary sexual characteristicsGO:00451371430.011
oogenesisGO:0048477560.011
regulation of multi organism processGO:00439001110.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
regulation of b cell activationGO:0050864810.011
glycosyl compound catabolic processGO:19016582060.011
sensory perceptionGO:00076002450.011
angiogenesisGO:00015252010.011
organism emergence from protective structureGO:007168440.011
peptidyl lysine modificationGO:0018205770.011
regulation of rna splicingGO:0043484370.011
mitotic cell cycle checkpointGO:0007093310.011
regulation of purine nucleotide metabolic processGO:19005421690.011
positive regulation of organelle organizationGO:00106381280.011
protein alkylationGO:0008213810.011
attachment of spindle microtubules to kinetochoreGO:000860840.011
regulation of protein targetingGO:1903533610.011
negative regulation of transferase activityGO:0051348850.011
neuroblast fate commitmentGO:001401710.011
lymphocyte differentiationGO:00300982420.011
mrna processingGO:0006397630.011
cation transportGO:00068123990.010
positive regulation of protein phosphorylationGO:00019342420.010
nucleoside phosphate catabolic processGO:19012922220.010
wnt signaling pathwayGO:00160551880.010
purine nucleoside catabolic processGO:00061522050.010
regulation of epithelial cell proliferationGO:00506781410.010
lateral inhibitionGO:004633110.010
respiratory system developmentGO:00605411900.010
regulation of exit from mitosisGO:000709610.010
regulation of actin filament based processGO:0032970990.010
regulation of protein complex assemblyGO:0043254830.010

Skp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.084
cancerDOID:16200.051
organ system cancerDOID:005068600.036
disease of anatomical entityDOID:700.018
nervous system diseaseDOID:86300.018