| nucleotide binding oligomerization domain containing signaling pathway | GO:0070423 | 6 | 1.000 | |
| cytoplasmic pattern recognition receptor signaling pathway | GO:0002753 | 10 | 1.000 | |
| marginal zone b cell differentiation | GO:0002315 | 2 | 1.000 | |
| activation of innate immune response | GO:0002218 | 56 | 1.000 | |
| toll like receptor 4 signaling pathway | GO:0034142 | 9 | 1.000 | |
| positive regulation of antimicrobial peptide biosynthetic process | GO:0002807 | 1 | 1.000 | Fly |
| regulation of defense response to fungus | GO:1900150 | 1 | 1.000 | Fly |
| regulation of antimicrobial humoral response | GO:0002759 | 3 | 1.000 | Fly |
| nucleotide binding oligomerization domain containing 1 signaling pathway | GO:0070427 | 5 | 1.000 | |
| antimicrobial peptide production | GO:0002775 | 2 | 1.000 | Fly |
| antimicrobial peptide biosynthetic process | GO:0002777 | 2 | 1.000 | Fly |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 1.000 | Human Mouse |
| toll like receptor signaling pathway | GO:0002224 | 38 | 1.000 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.999 | Mouse |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.999 | |
| negative regulation of tumor necrosis factor biosynthetic process | GO:0042536 | 1 | 0.999 | |
| germinal center formation | GO:0002467 | 16 | 0.999 | Mouse |
| response to muramyl dipeptide | GO:0032495 | 9 | 0.999 | Mouse |
| nucleotide binding oligomerization domain containing 2 signaling pathway | GO:0070431 | 6 | 0.999 | |
| positive regulation of antimicrobial peptide production | GO:0002225 | 1 | 0.999 | Fly |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.999 | Human Mouse |
| regulation of antimicrobial peptide production | GO:0002784 | 1 | 0.999 | Fly |
| follicular dendritic cell differentiation | GO:0002268 | 2 | 0.998 | Mouse |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.998 | |
| regulation of defense response to virus by host | GO:0050691 | 8 | 0.998 | Fly |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.998 | |
| t helper 1 type immune response | GO:0042088 | 25 | 0.998 | Mouse |
| immune response activating signal transduction | GO:0002757 | 116 | 0.997 | |
| alpha beta t cell differentiation | GO:0046632 | 69 | 0.997 | Mouse |
| t helper cell differentiation | GO:0042093 | 28 | 0.997 | Mouse |
| interleukin 12 biosynthetic process | GO:0042090 | 8 | 0.997 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.996 | Fly |
| regulation of innate immune response | GO:0045088 | 91 | 0.996 | Fly |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.996 | Mouse |
| myeloid dendritic cell differentiation | GO:0043011 | 16 | 0.994 | Mouse |
| activation of immune response | GO:0002253 | 138 | 0.993 | |
| regulation of antimicrobial peptide biosynthetic process | GO:0002805 | 1 | 0.992 | Fly |
| cd4 positive alpha beta t cell activation | GO:0035710 | 45 | 0.991 | Mouse |
| alpha beta t cell differentiation involved in immune response | GO:0002293 | 30 | 0.991 | Mouse |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.989 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 25 | 0.989 | |
| negative regulation of defense response | GO:0031348 | 77 | 0.987 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.987 | Human Mouse |
| defense response to fungus | GO:0050832 | 12 | 0.986 | Fly |
| cd4 positive alpha beta t cell differentiation | GO:0043367 | 41 | 0.985 | Mouse |
| circadian regulation of gene expression | GO:0032922 | 48 | 0.985 | Mouse |
| regulation of tumor necrosis factor production | GO:0032680 | 49 | 0.983 | |
| peptide biosynthetic process | GO:0043043 | 11 | 0.983 | Fly |
| nik nf kappab signaling | GO:0038061 | 14 | 0.982 | Mouse |
| follicular dendritic cell activation | GO:0002266 | 2 | 0.981 | Mouse |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.979 | Mouse |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.979 | |
| positive regulation of production of molecular mediator of immune response | GO:0002702 | 45 | 0.978 | Fly |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 30 | 0.977 | Mouse |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 51 | 0.977 | |
| cd4 positive alpha beta t cell differentiation involved in immune response | GO:0002294 | 28 | 0.976 | Mouse |
| cellular amine metabolic process | GO:0044106 | 44 | 0.974 | |
| regulation of interleukin 10 biosynthetic process | GO:0045074 | 1 | 0.973 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.971 | |
| regulation of defense response | GO:0031347 | 233 | 0.970 | |
| negative regulation of myeloid cell differentiation | GO:0045638 | 38 | 0.968 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.967 | Mouse |
| cytokine biosynthetic process | GO:0042089 | 68 | 0.966 | |
| antibacterial peptide production | GO:0002778 | 2 | 0.964 | Fly |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.963 | Mouse |
| negative regulation of cytokine biosynthetic process | GO:0042036 | 13 | 0.963 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.962 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.961 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.957 | Human Mouse |
| t helper 2 cell differentiation | GO:0045064 | 12 | 0.957 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.957 | Mouse |
| b cell differentiation | GO:0030183 | 78 | 0.957 | |
| myeloid dendritic cell activation | GO:0001773 | 25 | 0.954 | Mouse |
| t cell activation | GO:0042110 | 289 | 0.953 | Mouse |
| adaptive immune response | GO:0002250 | 155 | 0.951 | Mouse |
| negative regulation of cytokine production | GO:0001818 | 84 | 0.950 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.947 | |
| extracellular structure organization | GO:0043062 | 148 | 0.946 | Mouse |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.945 | Human Mouse |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 50 | 0.945 | |
| regulation of defense response to bacterium | GO:1900424 | 3 | 0.943 | Fly |
| positive regulation of defense response | GO:0031349 | 124 | 0.943 | Fly |
| lymphocyte differentiation | GO:0030098 | 242 | 0.942 | Mouse |
| defense response to bacterium | GO:0042742 | 119 | 0.940 | Fly |
| cell activation involved in immune response | GO:0002263 | 126 | 0.940 | Mouse |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.940 | Human |
| cellular response to lipid | GO:0071396 | 145 | 0.938 | Human Mouse |
| protein import into nucleus translocation | GO:0000060 | 12 | 0.938 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 59 | 0.938 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 65 | 0.937 | Fly |
| dendritic cell differentiation | GO:0097028 | 26 | 0.937 | Mouse |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 40 | 0.935 | Mouse |
| positive regulation of interleukin 10 biosynthetic process | GO:0045082 | 1 | 0.934 | |
| positive regulation of interferon gamma production | GO:0032729 | 39 | 0.934 | |
| defense response to protozoan | GO:0042832 | 25 | 0.933 | |
| negative regulation of interleukin 12 production | GO:0032695 | 10 | 0.930 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.927 | Mouse |
| leukocyte differentiation | GO:0002521 | 342 | 0.927 | Mouse |
| negative regulation of interleukin 12 biosynthetic process | GO:0045083 | 1 | 0.926 | |
| b cell activation | GO:0042113 | 161 | 0.924 | |
| positive regulation of interleukin 12 production | GO:0032735 | 21 | 0.923 | Mouse |
| interleukin 10 biosynthetic process | GO:0042091 | 1 | 0.923 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.923 | Mouse |
| cytokine production | GO:0001816 | 319 | 0.921 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.920 | Mouse |
| protein localization to nucleus | GO:0034504 | 121 | 0.919 | |
| humoral immune response | GO:0006959 | 57 | 0.918 | Fly |
| regionalization | GO:0003002 | 337 | 0.912 | |
| t cell differentiation | GO:0030217 | 174 | 0.912 | Mouse |
| cytokine metabolic process | GO:0042107 | 71 | 0.912 | |
| regulation of humoral immune response | GO:0002920 | 22 | 0.906 | Fly |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.906 | |
| skin development | GO:0043588 | 220 | 0.904 | Mouse |
| b cell activation involved in immune response | GO:0002312 | 50 | 0.895 | |
| regulation of antibacterial peptide biosynthetic process | GO:0002808 | 1 | 0.895 | Fly |
| circadian rhythm | GO:0007623 | 114 | 0.894 | Mouse |
| regulation of tumor necrosis factor biosynthetic process | GO:0042534 | 10 | 0.885 | |
| antibacterial peptide biosynthetic process | GO:0002780 | 2 | 0.883 | Fly |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.877 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.873 | Mouse |
| positive regulation of defense response to virus by host | GO:0002230 | 6 | 0.872 | Fly |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.871 | |
| response to dsrna | GO:0043331 | 30 | 0.870 | |
| regulation of interleukin 10 production | GO:0032653 | 21 | 0.862 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.860 | Mouse |
| t cell differentiation involved in immune response | GO:0002292 | 30 | 0.853 | Mouse |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.852 | |
| regulation of b cell activation | GO:0050864 | 81 | 0.850 | |
| inflammatory response | GO:0006954 | 244 | 0.849 | |
| spleen development | GO:0048536 | 39 | 0.845 | Mouse |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.844 | Mouse |
| negative regulation of immune system process | GO:0002683 | 209 | 0.843 | |
| regulation of interleukin 12 biosynthetic process | GO:0045075 | 8 | 0.835 | |
| cellular response to peptide | GO:1901653 | 92 | 0.834 | Human |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.831 | |
| antigen processing and presentation | GO:0019882 | 47 | 0.829 | Mouse |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.821 | Mouse |
| rhythmic process | GO:0048511 | 174 | 0.819 | Mouse |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.816 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.815 | Mouse |
| positive regulation of antimicrobial humoral response | GO:0002760 | 2 | 0.814 | Fly |
| amine metabolic process | GO:0009308 | 45 | 0.813 | |
| regulation of toll like receptor signaling pathway | GO:0034121 | 20 | 0.811 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.811 | |
| regulation of antibacterial peptide production | GO:0002786 | 1 | 0.810 | Fly |
| negative regulation of protein catabolic process | GO:0042177 | 36 | 0.809 | Mouse |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.807 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.803 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.802 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.793 | Mouse |
| response to organonitrogen compound | GO:0010243 | 246 | 0.785 | Human Mouse |
| type i interferon signaling pathway | GO:0060337 | 10 | 0.785 | |
| innate immune response | GO:0045087 | 157 | 0.784 | Fly |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.775 | Mouse |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.773 | |
| cellular response to type i interferon | GO:0071357 | 10 | 0.770 | |
| antibacterial humoral response | GO:0019731 | 8 | 0.746 | Fly |
| response to peptide | GO:1901652 | 136 | 0.737 | Human Mouse |
| positive regulation of leukocyte apoptotic process | GO:2000108 | 21 | 0.722 | |
| negative regulation of inflammatory response | GO:0050728 | 61 | 0.717 | |
| t cell activation involved in immune response | GO:0002286 | 43 | 0.712 | Mouse |
| regulation of defense response to virus | GO:0050688 | 18 | 0.706 | Fly |
| interferon gamma production | GO:0032609 | 67 | 0.693 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.688 | Fly |
| interleukin 12 production | GO:0032615 | 32 | 0.687 | |
| cell fate commitment | GO:0045165 | 210 | 0.677 | |
| regulation of interleukin 12 production | GO:0032655 | 30 | 0.676 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 61 | 0.670 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.661 | |
| nucleotide binding domain leucine rich repeat containing receptor signaling pathway | GO:0035872 | 6 | 0.661 | |
| apical constriction | GO:0003383 | 4 | 0.660 | |
| t helper 1 cell differentiation | GO:0045063 | 13 | 0.656 | Mouse |
| response to protozoan | GO:0001562 | 28 | 0.642 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.641 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.639 | |
| protein targeting | GO:0006605 | 143 | 0.632 | |
| response to interleukin 1 | GO:0070555 | 11 | 0.631 | Human |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.631 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.621 | Human |
| tumor necrosis factor biosynthetic process | GO:0042533 | 10 | 0.618 | |
| regulation of protein transport | GO:0051223 | 163 | 0.602 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.600 | |
| immune effector process | GO:0002252 | 321 | 0.595 | Mouse Fly |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.592 | |
| leukocyte apoptotic process | GO:0071887 | 71 | 0.585 | |
| negative regulation of t helper 2 cell differentiation | GO:0045629 | 4 | 0.585 | |
| regulation of type i interferon mediated signaling pathway | GO:0060338 | 7 | 0.579 | |
| myd88 dependent toll like receptor signaling pathway | GO:0002755 | 7 | 0.568 | |
| hair cycle | GO:0042633 | 90 | 0.564 | Mouse |
| positive regulation of cell death | GO:0010942 | 224 | 0.552 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.552 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.550 | Fly |
| positive regulation of mirna metabolic process | GO:2000630 | 1 | 0.549 | Human |
| regulation of binding | GO:0051098 | 111 | 0.548 | |
| negative regulation of toll like receptor signaling pathway | GO:0034122 | 14 | 0.541 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.533 | |
| cellular response to tumor necrosis factor | GO:0071356 | 21 | 0.529 | |
| regulation of cell activation | GO:0050865 | 289 | 0.527 | |
| positive regulation of interleukin 10 production | GO:0032733 | 12 | 0.526 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.524 | Fly |
| liver development | GO:0001889 | 66 | 0.524 | Mouse |
| protein catabolic process | GO:0030163 | 221 | 0.523 | Mouse |
| alpha beta t cell activation | GO:0046631 | 91 | 0.521 | Mouse |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 15 | 0.521 | |
| regulation of response to biotic stimulus | GO:0002831 | 38 | 0.517 | Fly |
| regulation of tyrosine phosphorylation of stat5 protein | GO:0042522 | 8 | 0.516 | |
| positive regulation of interferon alpha production | GO:0032727 | 4 | 0.506 | |
| regulation of t helper 1 cell differentiation | GO:0045625 | 7 | 0.504 | |
| interleukin 10 production | GO:0032613 | 23 | 0.504 | |
| keratinocyte differentiation | GO:0030216 | 48 | 0.499 | |
| regulation of protein localization | GO:0032880 | 231 | 0.498 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.496 | |
| growth involved in symbiotic interaction | GO:0044110 | 23 | 0.494 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.492 | |
| negative regulation of t helper 1 cell differentiation | GO:0045626 | 3 | 0.491 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.486 | |
| somatic diversification of immunoglobulins involved in immune response | GO:0002208 | 36 | 0.484 | |
| positive regulation of glial cell proliferation | GO:0060252 | 4 | 0.484 | |
| alpha beta t cell activation involved in immune response | GO:0002287 | 31 | 0.479 | Mouse |
| negative regulation of tumor necrosis factor production | GO:0032720 | 17 | 0.475 | |
| regulation of growth of symbiont in host | GO:0044126 | 19 | 0.474 | |
| regulation of interferon gamma production | GO:0032649 | 57 | 0.474 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.473 | |
| regulation of mirna metabolic process | GO:2000628 | 4 | 0.471 | Human |
| regulation of t cell activation | GO:0050863 | 170 | 0.470 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.468 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 45 | 0.466 | Mouse |
| regulation of sterol transport | GO:0032371 | 17 | 0.462 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.457 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.456 | |
| macrophage derived foam cell differentiation | GO:0010742 | 6 | 0.443 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.440 | |
| positive regulation of growth hormone receptor signaling pathway | GO:0060399 | 3 | 0.439 | |
| digestive system development | GO:0055123 | 200 | 0.429 | |
| positive regulation of cholesterol transport | GO:0032376 | 9 | 0.425 | |
| regulation of cellular amide metabolic process | GO:0034248 | 10 | 0.423 | Fly |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.422 | |
| glial cell apoptotic process | GO:0034349 | 3 | 0.414 | |
| tumor necrosis factor mediated signaling pathway | GO:0033209 | 13 | 0.410 | |
| positive regulation of translational initiation | GO:0045948 | 4 | 0.404 | |
| regulation of cytokine production involved in immune response | GO:0002718 | 26 | 0.400 | |
| regulation of cholesterol transport | GO:0032374 | 17 | 0.400 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.399 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.399 | |
| regulation of alpha beta t cell proliferation | GO:0046640 | 18 | 0.383 | |
| epidermis development | GO:0008544 | 187 | 0.382 | Mouse |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.377 | |
| jak stat cascade involved in growth hormone signaling pathway | GO:0060397 | 4 | 0.377 | |
| positive regulation of defense response to bacterium | GO:1900426 | 1 | 0.376 | Fly |
| negative regulation of innate immune response | GO:0045824 | 17 | 0.374 | |
| type i interferon production | GO:0032606 | 29 | 0.374 | |
| myd88 independent toll like receptor signaling pathway | GO:0002756 | 3 | 0.364 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.360 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.356 | |
| t cell apoptotic process | GO:0070231 | 39 | 0.354 | |
| positive regulation of type i interferon production | GO:0032481 | 14 | 0.349 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.347 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.346 | |
| regulation of interferon beta biosynthetic process | GO:0045357 | 4 | 0.342 | |
| cytokine production involved in immune response | GO:0002367 | 34 | 0.335 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.333 | Mouse |
| negative regulation of inflammatory response to antigenic stimulus | GO:0002862 | 10 | 0.333 | |
| osteoclast proliferation | GO:0002158 | 4 | 0.332 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.329 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.325 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 73 | 0.324 | |
| hair follicle development | GO:0001942 | 85 | 0.323 | Mouse |
| protein import into nucleus | GO:0006606 | 95 | 0.321 | |
| negative regulation of tumor necrosis factor superfamily cytokine production | GO:1903556 | 17 | 0.320 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.319 | |
| positive regulation of response to biotic stimulus | GO:0002833 | 15 | 0.313 | Fly |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 5 | 0.307 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.307 | Human |
| germ cell development | GO:0007281 | 185 | 0.306 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.302 | Mouse |
| positive regulation of interleukin 12 biosynthetic process | GO:0045084 | 6 | 0.300 | Mouse |
| b cell mediated immunity | GO:0019724 | 71 | 0.300 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.291 | Fly |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.291 | |
| defense response to other organism | GO:0098542 | 197 | 0.290 | Fly |
| positive regulation of jnk cascade | GO:0046330 | 46 | 0.290 | |
| sterol transport | GO:0015918 | 38 | 0.290 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.286 | |
| anion transport | GO:0006820 | 177 | 0.284 | |
| positive regulation of cellular amide metabolic process | GO:0034250 | 5 | 0.280 | Fly |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.279 | |
| negative regulation of mast cell proliferation | GO:0070667 | 1 | 0.279 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.277 | |
| negative regulation of cytokine production involved in immune response | GO:0002719 | 5 | 0.276 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.271 | |
| immune response inhibiting signal transduction | GO:0002765 | 4 | 0.270 | |
| regulation of nitric oxide biosynthetic process | GO:0045428 | 18 | 0.269 | Fly |
| immunoglobulin secretion | GO:0048305 | 17 | 0.269 | |
| regulation of myd88 independent toll like receptor signaling pathway | GO:0034127 | 1 | 0.268 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.265 | |
| interleukin 4 mediated signaling pathway | GO:0035771 | 2 | 0.265 | |
| necroptotic signaling pathway | GO:0097527 | 3 | 0.265 | |
| gastrulation | GO:0007369 | 116 | 0.261 | |
| regulation of peptide transport | GO:0090087 | 91 | 0.258 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.255 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.252 | |
| interferon beta biosynthetic process | GO:0045350 | 4 | 0.246 | |
| cellular amide metabolic process | GO:0043603 | 58 | 0.245 | Fly |
| response to peptide hormone | GO:0043434 | 127 | 0.243 | Human |
| amide transport | GO:0042886 | 138 | 0.241 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.239 | |
| interleukin 10 secretion | GO:0072608 | 4 | 0.238 | |
| necroptotic process | GO:0070266 | 21 | 0.237 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.236 | |
| humoral immune response mediated by circulating immunoglobulin | GO:0002455 | 14 | 0.236 | |
| t cell receptor signaling pathway | GO:0050852 | 46 | 0.235 | |
| mature b cell differentiation involved in immune response | GO:0002313 | 9 | 0.232 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.226 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.224 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.221 | |
| compound eye development | GO:0048749 | 1 | 0.220 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.219 | |
| b cell proliferation | GO:0042100 | 53 | 0.218 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.218 | Human Fly |
| defense response to virus | GO:0051607 | 68 | 0.216 | Fly |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.216 | Human |
| cytokine secretion | GO:0050663 | 72 | 0.215 | |
| negative regulation of growth | GO:0045926 | 99 | 0.215 | |
| interleukin 5 secretion | GO:0072603 | 2 | 0.213 | |
| single organism nuclear import | GO:1902593 | 95 | 0.212 | |
| response to light stimulus | GO:0009416 | 135 | 0.209 | |
| interferon gamma mediated signaling pathway | GO:0060333 | 5 | 0.207 | |
| positive regulation of t cell differentiation | GO:0045582 | 52 | 0.206 | |
| activation of janus kinase activity | GO:0042976 | 2 | 0.206 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.204 | |
| protein localization to organelle | GO:0033365 | 185 | 0.202 | |
| muscle cell development | GO:0055001 | 133 | 0.202 | |
| positive regulation of jak stat cascade | GO:0046427 | 22 | 0.200 | |
| nuclear transport | GO:0051169 | 139 | 0.197 | |
| regulation of type 2 immune response | GO:0002828 | 18 | 0.197 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 93 | 0.197 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.196 | |
| growth of symbiont in host | GO:0044117 | 23 | 0.195 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.191 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 29 | 0.190 | |
| protein import | GO:0017038 | 101 | 0.190 | |
| positive regulation of lipid transport | GO:0032370 | 22 | 0.188 | |
| positive regulation of t helper 1 cell differentiation | GO:0045627 | 4 | 0.187 | |
| response to tumor necrosis factor | GO:0034612 | 26 | 0.186 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.185 | |
| negative regulation of transcription factor import into nucleus | GO:0042992 | 13 | 0.184 | |
| regulation of lipid storage | GO:0010883 | 20 | 0.184 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.183 | |
| ensheathment of neurons | GO:0007272 | 76 | 0.181 | |
| alpha beta t cell proliferation | GO:0046633 | 21 | 0.179 | |
| negative regulation of intracellular protein transport | GO:0090317 | 27 | 0.179 | |
| cholesterol efflux | GO:0033344 | 24 | 0.178 | |
| response to exogenous dsrna | GO:0043330 | 22 | 0.174 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.174 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.170 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.170 | |
| negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002823 | 23 | 0.169 | |
| response to type i interferon | GO:0034340 | 12 | 0.168 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.167 | |
| neural tube development | GO:0021915 | 160 | 0.166 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.163 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.162 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.160 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.158 | |
| gland development | GO:0048732 | 330 | 0.158 | Mouse |
| notch signaling pathway | GO:0007219 | 71 | 0.155 | |
| positive regulation of antibacterial peptide production | GO:0002803 | 1 | 0.155 | Fly |
| regulation of dendritic cell cytokine production | GO:0002730 | 2 | 0.150 | |
| somatic recombination of immunoglobulin genes involved in immune response | GO:0002204 | 36 | 0.150 | |
| defense response to gram negative bacterium | GO:0050829 | 28 | 0.150 | Fly |
| chromatin modification | GO:0016568 | 187 | 0.148 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.148 | |
| positive regulation of type i interferon mediated signaling pathway | GO:0060340 | 4 | 0.147 | |
| regulation of myd88 dependent toll like receptor signaling pathway | GO:0034124 | 2 | 0.147 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.146 | |
| regulation of jun kinase activity | GO:0043506 | 40 | 0.146 | |
| mirna metabolic process | GO:0010586 | 10 | 0.146 | Human |
| transcription factor import into nucleus | GO:0042991 | 26 | 0.145 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.144 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.143 | Human |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.141 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.141 | |
| positive regulation of b cell activation | GO:0050871 | 49 | 0.141 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.135 | |
| stem cell proliferation | GO:0072089 | 117 | 0.135 | Fly |
| interleukin 8 production | GO:0032637 | 4 | 0.134 | |
| positive regulation of chronic inflammatory response | GO:0002678 | 4 | 0.133 | |
| dna recombination | GO:0006310 | 92 | 0.132 | |
| negative regulation of interleukin 5 production | GO:0032714 | 4 | 0.131 | |
| regulation of tyrosine phosphorylation of stat1 protein | GO:0042510 | 2 | 0.131 | |
| mature b cell differentiation | GO:0002335 | 13 | 0.131 | |
| regulation of jak stat cascade | GO:0046425 | 34 | 0.129 | |
| positive regulation of osteoclast differentiation | GO:0045672 | 15 | 0.129 | |
| t cell homeostasis | GO:0043029 | 35 | 0.128 | |
| positive regulation of dendritic cell apoptotic process | GO:2000670 | 3 | 0.128 | |
| regulation of gliogenesis | GO:0014013 | 50 | 0.126 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 55 | 0.124 | |
| gonad development | GO:0008406 | 141 | 0.123 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.123 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway | GO:2001267 | 4 | 0.123 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.123 | |
| peptide transport | GO:0015833 | 133 | 0.122 | |
| regulation of dendritic cell apoptotic process | GO:2000668 | 3 | 0.121 | |
| chromatin organization | GO:0006325 | 206 | 0.120 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.120 | Human |
| ruffle organization | GO:0031529 | 16 | 0.120 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.119 | |
| regulation of activation of jak2 kinase activity | GO:0010534 | 1 | 0.118 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.118 | |
| t cell migration | GO:0072678 | 19 | 0.116 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.115 | |
| negative regulation of interferon beta biosynthetic process | GO:0045358 | 1 | 0.113 | |
| interferon beta production | GO:0032608 | 16 | 0.113 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.112 | |
| regulation of interleukin 6 production | GO:0032675 | 55 | 0.112 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.112 | |
| regulation of toll like receptor 2 signaling pathway | GO:0034135 | 3 | 0.112 | |
| type 2 immune response | GO:0042092 | 23 | 0.112 | |
| positive regulation of regulatory t cell differentiation | GO:0045591 | 4 | 0.111 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.111 | |
| positive regulation of protein kinase b signaling | GO:0051897 | 32 | 0.110 | |
| peptide metabolic process | GO:0006518 | 46 | 0.109 | Fly |
| regulation of b cell proliferation | GO:0030888 | 39 | 0.108 | |
| positive regulation of tyrosine phosphorylation of stat protein | GO:0042531 | 15 | 0.108 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.107 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.106 | Human |
| negative regulation of growth of symbiont in host | GO:0044130 | 19 | 0.106 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.106 | |
| activation of mapkkk activity | GO:0000185 | 1 | 0.105 | |
| negative regulation of t cell differentiation | GO:0045581 | 23 | 0.105 | |
| toll like receptor 2 signaling pathway | GO:0034134 | 6 | 0.105 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 34 | 0.105 | |
| positive regulation of response to cytokine stimulus | GO:0060760 | 11 | 0.104 | |
| negative regulation of adaptive immune response | GO:0002820 | 25 | 0.103 | |
| protein maturation | GO:0051604 | 176 | 0.103 | |
| tyrosine phosphorylation of stat5 protein | GO:0042506 | 9 | 0.102 | |
| negative regulation of regulatory t cell differentiation | GO:0045590 | 2 | 0.102 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.101 | |
| response to uv b | GO:0010224 | 5 | 0.100 | |
| regulation of toll like receptor 4 signaling pathway | GO:0034143 | 4 | 0.100 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.100 | |
| programmed necrotic cell death | GO:0097300 | 28 | 0.100 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.100 | |
| lymphocyte apoptotic process | GO:0070227 | 54 | 0.100 | |
| cellularization | GO:0007349 | 1 | 0.100 | |
| regulation of b cell differentiation | GO:0045577 | 23 | 0.099 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.098 | |
| lymph node development | GO:0048535 | 18 | 0.097 | |
| positive regulation of isotype switching | GO:0045830 | 15 | 0.096 | |
| regulation of t helper 1 type immune response | GO:0002825 | 17 | 0.096 | |
| positive regulation of translational initiation by iron | GO:0045994 | 2 | 0.095 | |
| negative regulation of leukocyte proliferation | GO:0070664 | 46 | 0.095 | |
| response to nicotine | GO:0035094 | 6 | 0.095 | Human |
| regulation of canonical wnt signaling pathway | GO:0060828 | 82 | 0.094 | Human |
| organic hydroxy compound transport | GO:0015850 | 93 | 0.094 | |
| regulation of ion transport | GO:0043269 | 215 | 0.094 | |
| regulation of interleukin 5 secretion | GO:2000662 | 2 | 0.092 | |
| histone modification | GO:0016570 | 159 | 0.092 | |
| regulation of macrophage differentiation | GO:0045649 | 9 | 0.092 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 64 | 0.092 | |
| dendritic cell cytokine production | GO:0002371 | 3 | 0.092 | |
| tyrosine phosphorylation of stat protein | GO:0007260 | 23 | 0.091 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 58 | 0.091 | |
| negative regulation of macrophage derived foam cell differentiation | GO:0010745 | 1 | 0.091 | |
| respiratory tube development | GO:0030323 | 167 | 0.090 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 27 | 0.090 | |
| cd4 positive cd25 positive alpha beta regulatory t cell differentiation | GO:0002361 | 4 | 0.090 | |
| response to uv | GO:0009411 | 44 | 0.089 | |
| regulation of mast cell differentiation | GO:0060375 | 3 | 0.088 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.088 | |
| regulation of lipid transport | GO:0032368 | 36 | 0.088 | |
| exocrine system development | GO:0035272 | 45 | 0.087 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.086 | |
| t cell mediated immunity | GO:0002456 | 50 | 0.085 | |
| odontogenesis | GO:0042476 | 78 | 0.085 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 72 | 0.085 | |
| positive regulation of multi organism process | GO:0043902 | 26 | 0.085 | Fly |
| nitrogen compound transport | GO:0071705 | 271 | 0.085 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.084 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.084 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.084 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.083 | |
