Mus musculus

120 known processes

Nfkb1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105

(Aliases: NF-KB1,p105,NF-kappaB1,NF-kappaB,p50/p105,p50)

Nfkb1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide binding oligomerization domain containing signaling pathwayGO:007042361.000
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753101.000
marginal zone b cell differentiationGO:000231521.000
activation of innate immune responseGO:0002218561.000
toll like receptor 4 signaling pathwayGO:003414291.000
positive regulation of antimicrobial peptide biosynthetic processGO:000280711.000
Fly
regulation of defense response to fungusGO:190015011.000
Fly
regulation of antimicrobial humoral responseGO:000275931.000
Fly
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042751.000
antimicrobial peptide productionGO:000277521.000
Fly
antimicrobial peptide biosynthetic processGO:000277721.000
Fly
cellular response to molecule of bacterial originGO:0071219831.000
Human Mouse
toll like receptor signaling pathwayGO:0002224381.000
i kappab kinase nf kappab signalingGO:0007249850.999
Mouse
innate immune response activating signal transductionGO:0002758500.999
negative regulation of tumor necrosis factor biosynthetic processGO:004253610.999
germinal center formationGO:0002467160.999
Mouse
response to muramyl dipeptideGO:003249590.999
Mouse
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.999
positive regulation of antimicrobial peptide productionGO:000222510.999
Fly
cellular response to lipopolysaccharideGO:0071222770.999
Human Mouse
regulation of antimicrobial peptide productionGO:000278410.999
Fly
follicular dendritic cell differentiationGO:000226820.998
Mouse
immune response regulating signaling pathwayGO:00027641250.998
regulation of defense response to virus by hostGO:005069180.998
Fly
pattern recognition receptor signaling pathwayGO:0002221470.998
t helper 1 type immune responseGO:0042088250.998
Mouse
immune response activating signal transductionGO:00027571160.997
alpha beta t cell differentiationGO:0046632690.997
Mouse
t helper cell differentiationGO:0042093280.997
Mouse
interleukin 12 biosynthetic processGO:004209080.997
positive regulation of innate immune responseGO:0045089800.996
Fly
regulation of innate immune responseGO:0045088910.996
Fly
regulation of sequence specific dna binding transcription factor activityGO:00510901060.996
Mouse
myeloid dendritic cell differentiationGO:0043011160.994
Mouse
activation of immune responseGO:00022531380.993
regulation of antimicrobial peptide biosynthetic processGO:000280510.992
Fly
cd4 positive alpha beta t cell activationGO:0035710450.991
Mouse
alpha beta t cell differentiation involved in immune responseGO:0002293300.991
Mouse
cytokine mediated signaling pathwayGO:00192211150.989
lipopolysaccharide mediated signaling pathwayGO:0031663250.989
negative regulation of defense responseGO:0031348770.987
cellular response to biotic stimulusGO:0071216920.987
Human Mouse
defense response to fungusGO:0050832120.986
Fly
cd4 positive alpha beta t cell differentiationGO:0043367410.985
Mouse
circadian regulation of gene expressionGO:0032922480.985
Mouse
regulation of tumor necrosis factor productionGO:0032680490.983
peptide biosynthetic processGO:0043043110.983
Fly
nik nf kappab signalingGO:0038061140.982
Mouse
follicular dendritic cell activationGO:000226620.981
Mouse
positive regulation of cytokine productionGO:00018191740.979
Mouse
regulation of cellular amine metabolic processGO:0033238200.979
positive regulation of production of molecular mediator of immune responseGO:0002702450.978
Fly
positive regulation of nf kappab transcription factor activityGO:0051092300.977
Mouse
tumor necrosis factor superfamily cytokine productionGO:0071706510.977
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.976
Mouse
cellular amine metabolic processGO:0044106440.974
regulation of interleukin 10 biosynthetic processGO:004507410.973
tumor necrosis factor productionGO:0032640500.971
regulation of defense responseGO:00313472330.970
negative regulation of myeloid cell differentiationGO:0045638380.968
lymphocyte activation involved in immune responseGO:0002285930.967
Mouse
cytokine biosynthetic processGO:0042089680.966
antibacterial peptide productionGO:000277820.964
Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.963
Mouse
negative regulation of cytokine biosynthetic processGO:0042036130.963
regulation of lymphocyte activationGO:00512492400.962
regulation of cytokine productionGO:00018172660.961
response to molecule of bacterial originGO:00022371430.957
Human Mouse
t helper 2 cell differentiationGO:0045064120.957
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.957
Mouse
b cell differentiationGO:0030183780.957
myeloid dendritic cell activationGO:0001773250.954
Mouse
t cell activationGO:00421102890.953
Mouse
adaptive immune responseGO:00022501550.951
Mouse
negative regulation of cytokine productionGO:0001818840.950
cellular amino acid metabolic processGO:00065201030.947
extracellular structure organizationGO:00430621480.946
Mouse
response to lipopolysaccharideGO:00324961280.945
Human Mouse
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.945
regulation of defense response to bacteriumGO:190042430.943
Fly
positive regulation of defense responseGO:00313491240.943
Fly
lymphocyte differentiationGO:00300982420.942
Mouse
defense response to bacteriumGO:00427421190.940
Fly
cell activation involved in immune responseGO:00022631260.940
Mouse
cellular response to cytokine stimulusGO:00713451890.940
Human
cellular response to lipidGO:00713961450.938
Human Mouse
protein import into nucleus translocationGO:0000060120.938
regulation of cytokine biosynthetic processGO:0042035590.938
regulation of production of molecular mediator of immune responseGO:0002700650.937
Fly
dendritic cell differentiationGO:0097028260.937
Mouse
positive regulation of cytokine biosynthetic processGO:0042108400.935
Mouse
positive regulation of interleukin 10 biosynthetic processGO:004508210.934
positive regulation of interferon gamma productionGO:0032729390.934
defense response to protozoanGO:0042832250.933
negative regulation of interleukin 12 productionGO:0032695100.930
extracellular matrix organizationGO:00301981470.927
Mouse
leukocyte differentiationGO:00025213420.927
Mouse
negative regulation of interleukin 12 biosynthetic processGO:004508310.926
b cell activationGO:00421131610.924
positive regulation of interleukin 12 productionGO:0032735210.923
Mouse
interleukin 10 biosynthetic processGO:004209110.923
extrinsic apoptotic signaling pathwayGO:00971911260.923
Mouse
cytokine productionGO:00018163190.921
apoptotic signaling pathwayGO:00971903060.920
Mouse
protein localization to nucleusGO:00345041210.919
humoral immune responseGO:0006959570.918
Fly
regionalizationGO:00030023370.912
t cell differentiationGO:00302171740.912
Mouse
cytokine metabolic processGO:0042107710.912
regulation of humoral immune responseGO:0002920220.906
Fly
immunoglobulin mediated immune responseGO:0016064690.906
skin developmentGO:00435882200.904
Mouse
b cell activation involved in immune responseGO:0002312500.895
regulation of antibacterial peptide biosynthetic processGO:000280810.895
Fly
circadian rhythmGO:00076231140.894
Mouse
regulation of tumor necrosis factor biosynthetic processGO:0042534100.885
antibacterial peptide biosynthetic processGO:000278020.883
Fly
negative regulation of protein metabolic processGO:00512482820.877
myeloid cell differentiationGO:00300992330.873
Mouse
positive regulation of defense response to virus by hostGO:000223060.872
Fly
regulation of leukocyte differentiationGO:19021051590.871
response to dsrnaGO:0043331300.870
regulation of interleukin 10 productionGO:0032653210.862
myeloid leukocyte activationGO:0002274830.860
Mouse
t cell differentiation involved in immune responseGO:0002292300.853
Mouse
regulation of cellular amino acid metabolic processGO:000652150.852
regulation of b cell activationGO:0050864810.850
inflammatory responseGO:00069542440.849
spleen developmentGO:0048536390.845
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.844
Mouse
negative regulation of immune system processGO:00026832090.843
regulation of interleukin 12 biosynthetic processGO:004507580.835
cellular response to peptideGO:1901653920.834
Human
leukocyte mediated immunityGO:00024431740.831
antigen processing and presentationGO:0019882470.829
Mouse
leukocyte activation involved in immune responseGO:00023661260.821
Mouse
rhythmic processGO:00485111740.819
Mouse
interspecies interaction between organismsGO:0044419830.816
regulation of apoptotic signaling pathwayGO:20012331970.815
Mouse
positive regulation of antimicrobial humoral responseGO:000276020.814
Fly
amine metabolic processGO:0009308450.813
regulation of toll like receptor signaling pathwayGO:0034121200.811
positive regulation of programmed cell deathGO:00430682180.811
regulation of antibacterial peptide productionGO:000278610.810
Fly
negative regulation of protein catabolic processGO:0042177360.809
Mouse
regulation of leukocyte proliferationGO:00706631210.807
intracellular receptor signaling pathwayGO:0030522740.803
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.802
myeloid leukocyte differentiationGO:00025731190.793
Mouse
response to organonitrogen compoundGO:00102432460.785
Human Mouse
type i interferon signaling pathwayGO:0060337100.785
innate immune responseGO:00450871570.784
Fly
negative regulation of apoptotic signaling pathwayGO:20012341040.775
Mouse
reactive oxygen species biosynthetic processGO:190340980.773
cellular response to type i interferonGO:0071357100.770
antibacterial humoral responseGO:001973180.746
Fly
response to peptideGO:19016521360.737
Human Mouse
positive regulation of leukocyte apoptotic processGO:2000108210.722
negative regulation of inflammatory responseGO:0050728610.717
t cell activation involved in immune responseGO:0002286430.712
Mouse
regulation of defense response to virusGO:0050688180.706
Fly
interferon gamma productionGO:0032609670.693
production of molecular mediator of immune responseGO:00024401030.688
Fly
interleukin 12 productionGO:0032615320.687
cell fate commitmentGO:00451652100.677
regulation of interleukin 12 productionGO:0032655300.676
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.670
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.661
nucleotide binding domain leucine rich repeat containing receptor signaling pathwayGO:003587260.661
apical constrictionGO:000338340.660
t helper 1 cell differentiationGO:0045063130.656
Mouse
response to protozoanGO:0001562280.642
negative regulation of protein modification processGO:00314001630.641
negative regulation of cell activationGO:00508661110.639
protein targetingGO:00066051430.632
response to interleukin 1GO:0070555110.631
Human
regulation of stress activated mapk cascadeGO:0032872690.631
negative regulation of molecular functionGO:00440922580.621
Human
tumor necrosis factor biosynthetic processGO:0042533100.618
regulation of protein transportGO:00512231630.602
regulation of transcription factor import into nucleusGO:0042990240.600
immune effector processGO:00022523210.595
Mouse Fly
positive regulation of protein modification processGO:00314012990.592
leukocyte apoptotic processGO:0071887710.585
negative regulation of t helper 2 cell differentiationGO:004562940.585
regulation of type i interferon mediated signaling pathwayGO:006033870.579
myd88 dependent toll like receptor signaling pathwayGO:000275570.568
hair cycleGO:0042633900.564
Mouse
positive regulation of cell deathGO:00109422240.552
regulation of t cell differentiationGO:0045580830.552
regulation of multi organism processGO:00439001110.550
Fly
positive regulation of mirna metabolic processGO:200063010.549
Human
regulation of bindingGO:00510981110.548
negative regulation of toll like receptor signaling pathwayGO:0034122140.541
cell type specific apoptotic processGO:00972852680.533
cellular response to tumor necrosis factorGO:0071356210.529
regulation of cell activationGO:00508652890.527
positive regulation of interleukin 10 productionGO:0032733120.526
cellular response to dna damage stimulusGO:00069742070.524
Fly
liver developmentGO:0001889660.524
Mouse
protein catabolic processGO:00301632210.523
Mouse
alpha beta t cell activationGO:0046631910.521
Mouse
negative regulation of nf kappab transcription factor activityGO:0032088150.521
regulation of response to biotic stimulusGO:0002831380.517
Fly
regulation of tyrosine phosphorylation of stat5 proteinGO:004252280.516
positive regulation of interferon alpha productionGO:003272740.506
regulation of t helper 1 cell differentiationGO:004562570.504
interleukin 10 productionGO:0032613230.504
keratinocyte differentiationGO:0030216480.499
regulation of protein localizationGO:00328802310.498
regulation of protein localization to nucleusGO:1900180600.496
growth involved in symbiotic interactionGO:0044110230.494
positive regulation of cellular amine metabolic processGO:003324050.492
negative regulation of t helper 1 cell differentiationGO:004562630.491
lymphocyte mediated immunityGO:00024491390.486
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.484
positive regulation of glial cell proliferationGO:006025240.484
alpha beta t cell activation involved in immune responseGO:0002287310.479
Mouse
negative regulation of tumor necrosis factor productionGO:0032720170.475
regulation of growth of symbiont in hostGO:0044126190.474
regulation of interferon gamma productionGO:0032649570.474
stress activated mapk cascadeGO:0051403800.473
regulation of mirna metabolic processGO:200062840.471
Human
regulation of t cell activationGO:00508631700.470
regulation of intracellular protein transportGO:0033157820.468
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.466
Mouse
regulation of sterol transportGO:0032371170.462
regulation of mapk cascadeGO:00434082480.457
peptidyl tyrosine phosphorylationGO:00181081430.456
macrophage derived foam cell differentiationGO:001074260.443
nucleocytoplasmic transportGO:00069131390.440
positive regulation of growth hormone receptor signaling pathwayGO:006039930.439
digestive system developmentGO:00551232000.429
positive regulation of cholesterol transportGO:003237690.425
regulation of cellular amide metabolic processGO:0034248100.423
Fly
t cell differentiation in thymusGO:0033077770.422
glial cell apoptotic processGO:003434930.414
tumor necrosis factor mediated signaling pathwayGO:0033209130.410
positive regulation of translational initiationGO:004594840.404
regulation of cytokine production involved in immune responseGO:0002718260.400
regulation of cholesterol transportGO:0032374170.400
regulation of protein targetingGO:1903533610.399
regulation of cellular ketone metabolic processGO:0010565660.399
regulation of alpha beta t cell proliferationGO:0046640180.383
epidermis developmentGO:00085441870.382
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.377
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.377
positive regulation of defense response to bacteriumGO:190042610.376
Fly
negative regulation of innate immune responseGO:0045824170.374
type i interferon productionGO:0032606290.374
myd88 independent toll like receptor signaling pathwayGO:000275630.364
regulation of cell cycleGO:00517262810.360
regulation of myeloid cell differentiationGO:0045637960.356
t cell apoptotic processGO:0070231390.354
positive regulation of type i interferon productionGO:0032481140.349
erk1 and erk2 cascadeGO:0070371770.347
regulation of reactive oxygen species biosynthetic processGO:190342620.346
regulation of interferon beta biosynthetic processGO:004535740.342
cytokine production involved in immune responseGO:0002367340.335
macromolecule catabolic processGO:00090572810.333
Mouse
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.333
osteoclast proliferationGO:000215840.332
positive regulation of apoptotic signaling pathwayGO:2001235950.329
regulation of cytoplasmic transportGO:19036491120.325
positive regulation of leukocyte proliferationGO:0070665730.324
hair follicle developmentGO:0001942850.323
Mouse
protein import into nucleusGO:0006606950.321
negative regulation of tumor necrosis factor superfamily cytokine productionGO:1903556170.320
regulation of map kinase activityGO:00434051200.319
positive regulation of response to biotic stimulusGO:0002833150.313
Fly
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.307
cellular response to organonitrogen compoundGO:00714171450.307
Human
germ cell developmentGO:00072811850.306
regulation of protein catabolic processGO:00421761080.302
Mouse
positive regulation of interleukin 12 biosynthetic processGO:004508460.300
Mouse
b cell mediated immunityGO:0019724710.300
negative regulation of cell proliferationGO:00082852960.291
Fly
cellular ketone metabolic processGO:0042180840.291
defense response to other organismGO:00985421970.290
Fly
positive regulation of jnk cascadeGO:0046330460.290
sterol transportGO:0015918380.290
ribose phosphate metabolic processGO:00196932910.286
anion transportGO:00068201770.284
positive regulation of cellular amide metabolic processGO:003425050.280
Fly
positive regulation of reactive oxygen species biosynthetic processGO:190342820.279
negative regulation of mast cell proliferationGO:007066710.279
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.277
negative regulation of cytokine production involved in immune responseGO:000271950.276
regulation of inflammatory responseGO:00507271470.271
immune response inhibiting signal transductionGO:000276540.270
regulation of nitric oxide biosynthetic processGO:0045428180.269
Fly
immunoglobulin secretionGO:0048305170.269
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.268
epithelial cell proliferationGO:00506731740.265
interleukin 4 mediated signaling pathwayGO:003577120.265
necroptotic signaling pathwayGO:009752730.265
gastrulationGO:00073691160.261
regulation of peptide transportGO:0090087910.258
positive regulation of cell activationGO:00508671580.255
cytoplasmic transportGO:00164822340.252
interferon beta biosynthetic processGO:004535040.246
cellular amide metabolic processGO:0043603580.245
Fly
response to peptide hormoneGO:00434341270.243
Human
amide transportGO:00428861380.241
purine ribonucleoside metabolic processGO:00461282410.239
interleukin 10 secretionGO:007260840.238
necroptotic processGO:0070266210.237
regulation of response to woundingGO:19030341890.236
humoral immune response mediated by circulating immunoglobulinGO:0002455140.236
t cell receptor signaling pathwayGO:0050852460.235
mature b cell differentiation involved in immune responseGO:000231390.232
lymphocyte proliferationGO:00466511640.226
positive regulation of lymphocyte activationGO:00512511400.224
regulation of lymphocyte differentiationGO:00456191070.221
compound eye developmentGO:004874910.220
regulation of establishment of protein localizationGO:00702011810.219
b cell proliferationGO:0042100530.218
organonitrogen compound biosynthetic processGO:19015661920.218
Human Fly
defense response to virusGO:0051607680.216
Fly
cellular response to organic cyclic compoundGO:0071407870.216
Human
cytokine secretionGO:0050663720.215
negative regulation of growthGO:0045926990.215
interleukin 5 secretionGO:007260320.213
single organism nuclear importGO:1902593950.212
response to light stimulusGO:00094161350.209
interferon gamma mediated signaling pathwayGO:006033350.207
positive regulation of t cell differentiationGO:0045582520.206
activation of janus kinase activityGO:004297620.206
actin cytoskeleton organizationGO:00300362200.204
protein localization to organelleGO:00333651850.202
muscle cell developmentGO:00550011330.202
positive regulation of jak stat cascadeGO:0046427220.200
nuclear transportGO:00511691390.197
regulation of type 2 immune responseGO:0002828180.197
regulation of peptidyl tyrosine phosphorylationGO:0050730930.197
regulation of nucleocytoplasmic transportGO:0046822730.196
growth of symbiont in hostGO:0044117230.195
regulation of proteolysisGO:00301621640.191
intracellular steroid hormone receptor signaling pathwayGO:0030518290.190
protein importGO:00170381010.190
positive regulation of lipid transportGO:0032370220.188
positive regulation of t helper 1 cell differentiationGO:004562740.187
response to tumor necrosis factorGO:0034612260.186
regulation of jnk cascadeGO:0046328620.185
negative regulation of transcription factor import into nucleusGO:0042992130.184
regulation of lipid storageGO:0010883200.184
negative regulation of lymphocyte activationGO:0051250910.183
ensheathment of neuronsGO:0007272760.181
alpha beta t cell proliferationGO:0046633210.179
negative regulation of intracellular protein transportGO:0090317270.179
cholesterol effluxGO:0033344240.178
response to exogenous dsrnaGO:0043330220.174
regulation of membrane potentialGO:00423911920.174
reactive nitrogen species metabolic processGO:200105700.170
regulation of intracellular transportGO:00323861590.170
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.169
response to type i interferonGO:0034340120.168
positive regulation of protein serine threonine kinase activityGO:00719021060.167
neural tube developmentGO:00219151600.166
regulation of lymphocyte proliferationGO:00506701170.163
positive regulation of proteolysisGO:0045862850.162
positive regulation of endopeptidase activityGO:0010950430.160
regulation of kinase activityGO:00435492490.158
gland developmentGO:00487323300.158
Mouse
notch signaling pathwayGO:0007219710.155
positive regulation of antibacterial peptide productionGO:000280310.155
Fly
regulation of dendritic cell cytokine productionGO:000273020.150
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.150
defense response to gram negative bacteriumGO:0050829280.150
Fly
chromatin modificationGO:00165681870.148
osteoclast differentiationGO:0030316620.148
positive regulation of type i interferon mediated signaling pathwayGO:006034040.147
regulation of myd88 dependent toll like receptor signaling pathwayGO:003412420.147
positive regulation of map kinase activityGO:0043406840.146
regulation of jun kinase activityGO:0043506400.146
mirna metabolic processGO:0010586100.146
Human
transcription factor import into nucleusGO:0042991260.145
multicellular organismal homeostasisGO:00488711640.144
wnt signaling pathwayGO:00160551880.143
Human
intrinsic apoptotic signaling pathwayGO:00971931320.141
sensory organ morphogenesisGO:00905962420.141
positive regulation of b cell activationGO:0050871490.141
positive regulation of peptidase activityGO:0010952490.135
stem cell proliferationGO:00720891170.135
Fly
interleukin 8 productionGO:003263740.134
positive regulation of chronic inflammatory responseGO:000267840.133
dna recombinationGO:0006310920.132
negative regulation of interleukin 5 productionGO:003271440.131
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.131
mature b cell differentiationGO:0002335130.131
regulation of jak stat cascadeGO:0046425340.129
positive regulation of osteoclast differentiationGO:0045672150.129
t cell homeostasisGO:0043029350.128
positive regulation of dendritic cell apoptotic processGO:200067030.128
regulation of gliogenesisGO:0014013500.126
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.124
gonad developmentGO:00084061410.123
immune response regulating cell surface receptor signaling pathwayGO:0002768800.123
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126740.123
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.123
peptide transportGO:00158331330.122
regulation of dendritic cell apoptotic processGO:200066830.121
chromatin organizationGO:00063252060.120
regulation of wnt signaling pathwayGO:00301111230.120
Human
ruffle organizationGO:0031529160.120
erythrocyte differentiationGO:0030218880.119
regulation of activation of jak2 kinase activityGO:001053410.118
protein modification by small protein conjugationGO:00324461870.118
t cell migrationGO:0072678190.116
positive regulation of t cell activationGO:00508701010.115
negative regulation of interferon beta biosynthetic processGO:004535810.113
interferon beta productionGO:0032608160.113
negative regulation of phosphate metabolic processGO:00459361840.112
regulation of interleukin 6 productionGO:0032675550.112
regulation of reactive oxygen species metabolic processGO:2000377400.112
regulation of toll like receptor 2 signaling pathwayGO:003413530.112
type 2 immune responseGO:0042092230.112
positive regulation of regulatory t cell differentiationGO:004559140.111
regulation of protein kinase activityGO:00458592320.111
positive regulation of protein kinase b signalingGO:0051897320.110
peptide metabolic processGO:0006518460.109
Fly
regulation of b cell proliferationGO:0030888390.108
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531150.108
protein autophosphorylationGO:0046777610.107
response to organic cyclic compoundGO:00140701980.106
Human
negative regulation of growth of symbiont in hostGO:0044130190.106
positive regulation of hydrolase activityGO:00513451480.106
activation of mapkkk activityGO:000018510.105
negative regulation of t cell differentiationGO:0045581230.105
toll like receptor 2 signaling pathwayGO:003413460.105
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.105
positive regulation of response to cytokine stimulusGO:0060760110.104
negative regulation of adaptive immune responseGO:0002820250.103
protein maturationGO:00516041760.103
tyrosine phosphorylation of stat5 proteinGO:004250690.102
negative regulation of regulatory t cell differentiationGO:004559020.102
regulation of interleukin 8 productionGO:003267730.101
response to uv bGO:001022450.100
regulation of toll like receptor 4 signaling pathwayGO:003414340.100
regulation of osteoblast differentiationGO:0045667670.100
programmed necrotic cell deathGO:0097300280.100
digestive tract morphogenesisGO:00485461470.100
lymphocyte apoptotic processGO:0070227540.100
cellularizationGO:000734910.100
regulation of b cell differentiationGO:0045577230.099
divalent inorganic cation transportGO:00725111780.098
lymph node developmentGO:0048535180.097
positive regulation of isotype switchingGO:0045830150.096
regulation of t helper 1 type immune responseGO:0002825170.096
positive regulation of translational initiation by ironGO:004599420.095
negative regulation of leukocyte proliferationGO:0070664460.095
response to nicotineGO:003509460.095
Human
regulation of canonical wnt signaling pathwayGO:0060828820.094
Human
organic hydroxy compound transportGO:0015850930.094
regulation of ion transportGO:00432692150.094
regulation of interleukin 5 secretionGO:200066220.092
histone modificationGO:00165701590.092
regulation of macrophage differentiationGO:004564990.092
antigen receptor mediated signaling pathwayGO:0050851640.092
dendritic cell cytokine productionGO:000237130.092
tyrosine phosphorylation of stat proteinGO:0007260230.091
regulation of myeloid leukocyte differentiationGO:0002761580.091
negative regulation of macrophage derived foam cell differentiationGO:001074510.091
respiratory tube developmentGO:00303231670.090
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.090
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.090
response to uvGO:0009411440.089
regulation of mast cell differentiationGO:006037530.088
establishment of protein localization to organelleGO:00725941180.088
regulation of lipid transportGO:0032368360.088
exocrine system developmentGO:0035272450.087
peptidyl serine phosphorylationGO:0018105740.086
t cell mediated immunityGO:0002456500.085
odontogenesisGO:0042476780.085
immune response activating cell surface receptor signaling pathwayGO:0002429720.085
positive regulation of multi organism processGO:0043902260.085
Fly
nitrogen compound transportGO:00717052710.085
epithelial tube morphogenesisGO:00605623030.084
regulation of protein complex assemblyGO:0043254830.084
peptidyl amino acid modificationGO:00181933360.084
morphogenesis of a branching epitheliumGO:00611381930.083

Nfkb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.485
disease of cellular proliferationDOID:1456600.485
immune system diseaseDOID:291400.373
disease of anatomical entityDOID:700.373
hematopoietic system diseaseDOID:7400.373
primary immunodeficiency diseaseDOID:61200.298
blood protein diseaseDOID:62000.298
agammaglobulinemiaDOID:258300.298
common variable immunodeficiencyDOID:1217700.298
b cell deficiencyDOID:211500.298
organ system cancerDOID:005068600.244
bone remodeling diseaseDOID:008000500.147
bone diseaseDOID:008000100.147
osteopetrosisDOID:1353300.147
musculoskeletal system diseaseDOID:1700.147
connective tissue diseaseDOID:6500.147
osteosclerosisDOID:425400.147