Mus musculus

40 known processes

Nfkb2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100

(Aliases: lyt,NF-kappaB2,p49/p100,p49,p50B,p52)

Nfkb2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
marginal zone b cell differentiationGO:000231521.000
nucleotide binding oligomerization domain containing signaling pathwayGO:007042361.000
positive regulation of cytokine biosynthetic processGO:0042108401.000
Mouse
follicular dendritic cell differentiationGO:000226821.000
germinal center formationGO:0002467161.000
nik nf kappab signalingGO:0038061141.000
myeloid dendritic cell differentiationGO:0043011161.000
Mouse
t helper 2 cell differentiationGO:0045064121.000
spleen developmentGO:0048536391.000
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294281.000
Mouse
lymphocyte differentiationGO:00300982421.000
Mouse
interleukin 10 secretionGO:007260841.000
response to muramyl dipeptideGO:003249591.000
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630571.000
cd4 positive alpha beta t cell activationGO:0035710451.000
Mouse
regulation of antimicrobial humoral responseGO:000275931.000
Fly
leukocyte differentiationGO:00025213421.000
Mouse
interleukin 5 secretionGO:007260321.000
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043161.000
myeloid dendritic cell activationGO:0001773251.000
Mouse
regulation of antimicrobial peptide productionGO:000278411.000
Fly
positive regulation of translational initiationGO:004594841.000
t helper cell differentiationGO:0042093281.000
Mouse
i kappab kinase nf kappab signalingGO:0007249851.000
Mouse
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753101.000
defense response to bacteriumGO:00427421191.000
Fly
toll like receptor 4 signaling pathwayGO:003414291.000
cd4 positive alpha beta t cell differentiationGO:0043367411.000
Mouse
cellular response to lipopolysaccharideGO:0071222771.000
Mouse
dendritic cell differentiationGO:0097028261.000
Mouse
myeloid cell differentiationGO:00300992331.000
Mouse
immune response activating signal transductionGO:00027571161.000
regulation of sequence specific dna binding transcription factor activityGO:00510901061.000
Mouse
toll like receptor signaling pathwayGO:0002224381.000
activation of innate immune responseGO:0002218561.000
antimicrobial peptide productionGO:000277521.000
Fly
b cell differentiationGO:0030183781.000
cellular response to molecule of bacterial originGO:0071219831.000
Mouse
alpha beta t cell differentiation involved in immune responseGO:0002293301.000
Mouse
cellular response to biotic stimulusGO:0071216921.000
Mouse
immunoglobulin secretionGO:0048305171.000
follicular dendritic cell activationGO:000226621.000
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042751.000
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601451.000
negative regulation of tumor necrosis factor biosynthetic processGO:004253611.000
tumor necrosis factor mediated signaling pathwayGO:0033209131.000
cytokine mediated signaling pathwayGO:00192211151.000
t cell differentiationGO:00302171741.000
Mouse
somatic diversification of immunoglobulins involved in immune responseGO:0002208361.000
production of molecular mediator of immune responseGO:00024401030.999
Fly
regulation of interleukin 10 biosynthetic processGO:004507410.999
myeloid leukocyte activationGO:0002274830.999
Mouse
innate immune response activating signal transductionGO:0002758500.999
immunoglobulin mediated immune responseGO:0016064690.999
negative regulation of interleukin 10 secretionGO:200118020.999
positive regulation of chronic inflammatory responseGO:000267840.999
regulation of tumor necrosis factor biosynthetic processGO:0042534100.999
negative regulation of cytokine biosynthetic processGO:0042036130.999
Mouse
t cell differentiation involved in immune responseGO:0002292300.999
Mouse
negative regulation of b cell activationGO:0050869270.999
extracellular structure organizationGO:00430621480.999
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.999
Mouse
adaptive immune responseGO:00022501550.999
regulation of defense response to fungusGO:190015010.999
Fly
regulation of interleukin 12 biosynthetic processGO:004507580.999
Mouse
positive regulation of interleukin 12 productionGO:0032735210.998
Mouse
lymph node developmentGO:0048535180.998
regulation of myeloid cell differentiationGO:0045637960.998
extrinsic apoptotic signaling pathwayGO:00971911260.998
Mouse
positive regulation of translational initiation by ironGO:004599420.998
regulation of cytokine biosynthetic processGO:0042035590.998
Mouse
t cell activationGO:00421102890.998
Mouse
positive regulation of interleukin 10 biosynthetic processGO:004508210.998
alpha beta t cell activation involved in immune responseGO:0002287310.998
Mouse
circadian rhythmGO:00076231140.997
Mouse
defense response to protozoanGO:0042832250.997
alpha beta t cell differentiationGO:0046632690.997
Mouse
osteoclast proliferationGO:000215840.997
regulation of antibacterial peptide productionGO:000278610.997
Fly
peptide biosynthetic processGO:0043043110.997
Fly
regulation of lymphocyte differentiationGO:00456191070.997
pattern recognition receptor signaling pathwayGO:0002221470.996
b cell activation involved in immune responseGO:0002312500.996
lymphocyte proliferationGO:00466511640.996
humoral immune responseGO:0006959570.996
Fly
necroptotic signaling pathwayGO:009752730.996
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.996
Fly
regulation of interleukin 13 secretionGO:200066520.996
b cell activationGO:00421131610.995
positive regulation of leukocyte apoptotic processGO:2000108210.995
positive regulation of myoblast differentiationGO:004566380.995
regulation of cytokine productionGO:00018172660.995
Mouse
negative regulation of myeloid cell differentiationGO:0045638380.995
humoral immune response mediated by circulating immunoglobulinGO:0002455140.995
regulation of t cell activationGO:00508631700.995
positive regulation of lipid transportGO:0032370220.995
regulation of leukocyte differentiationGO:19021051590.995
somatic diversification of immunoglobulinsGO:0016445430.995
positive regulation of defense responseGO:00313491240.995
Fly
interleukin 10 biosynthetic processGO:004209110.994
t cell differentiation in thymusGO:0033077770.994
ensheathment of neuronsGO:0007272760.994
lymphocyte mediated immunityGO:00024491390.994
negative regulation of interleukin 12 biosynthetic processGO:004508310.993
Mouse
interleukin 12 biosynthetic processGO:004209080.993
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.993
Mouse
cytokine biosynthetic processGO:0042089680.993
Mouse
axon ensheathmentGO:0008366760.993
regulation of vitamin d biosynthetic processGO:006055610.993
defense response to other organismGO:00985421970.993
Fly
positive regulation of jun kinase activityGO:0043507300.993
cellular response to dna damage stimulusGO:00069742070.993
Fly
positive regulation of cellular amine metabolic processGO:003324050.993
negative regulation of t helper 2 cell differentiationGO:004562940.992
leukocyte proliferationGO:00706611720.992
b cell mediated immunityGO:0019724710.992
t cell receptor signaling pathwayGO:0050852460.991
immune response regulating signaling pathwayGO:00027641250.991
apoptotic signaling pathwayGO:00971903060.991
Mouse
cellular response to amino acid stimulusGO:0071230290.991
antibacterial peptide productionGO:000277820.991
Fly
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.991
interleukin 13 secretionGO:007261120.991
regulation of multi organism processGO:00439001110.990
Fly
regulation of apoptotic signaling pathwayGO:20012331970.990
Mouse
lipopolysaccharide mediated signaling pathwayGO:0031663250.990
negative regulation of interleukin 5 productionGO:003271440.990
myd88 independent toll like receptor signaling pathwayGO:000275630.990
fat soluble vitamin biosynthetic processGO:004236240.990
defense response to fungusGO:0050832120.989
Fly
antimicrobial peptide biosynthetic processGO:000277720.989
Fly
positive regulation of lymphocyte activationGO:00512511400.988
positive regulation of t cell differentiationGO:0045582520.988
positive regulation of isotype switching to igg isotypesGO:004830470.986
regulation of leukocyte proliferationGO:00706631210.986
nuclear importGO:0051170950.986
cellular amide metabolic processGO:0043603580.986
Fly
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.986
protein import into nucleus translocationGO:0000060120.986
positive regulation of innate immune responseGO:0045089800.985
Fly
amine metabolic processGO:0009308450.985
extracellular matrix organizationGO:00301981470.984
response to molecule of bacterial originGO:00022371430.984
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.984
positive regulation of interferon gamma productionGO:0032729390.983
negative regulation of alpha beta t cell differentiationGO:0046639120.983
positive regulation of osteoclast differentiationGO:0045672150.982
melanin metabolic processGO:0006582120.982
regulation of neutrophil differentiationGO:004565820.982
positive regulation of cytokine productionGO:00018191740.982
Mouse
regulation of interleukin 5 secretionGO:200066220.981
regulation of cellular amino acid metabolic processGO:000652150.981
positive regulation of cell deathGO:00109422240.981
regulation of tumor necrosis factor productionGO:0032680490.981
regulation of translational initiation by ironGO:000644720.981
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.981
negative regulation of t helper 1 cell differentiationGO:004562630.980
gliogenesisGO:00420631410.980
positive regulation of chronic inflammatory response to antigenic stimulusGO:000287620.980
response to protozoanGO:0001562280.979
cellular amine metabolic processGO:0044106440.979
skeletal muscle fiber developmentGO:0048741580.978
protein localization to nucleusGO:00345041210.976
positive regulation of antimicrobial peptide productionGO:000222510.975
Fly
regulation of interleukin 10 productionGO:0032653210.975
regulation of reactive oxygen species metabolic processGO:2000377400.975
response to peptideGO:19016521360.974
Mouse
molting cycleGO:0042303900.972
Mouse
regulation of bindingGO:00510981110.972
defense response to gram negative bacteriumGO:0050829280.970
Fly
positive regulation of heat generationGO:003165270.969
regulation of interleukin 10 secretionGO:200117940.969
protein targetingGO:00066051430.968
cellular response to tumor necrosis factorGO:0071356210.966
cellular response to lipidGO:00713961450.966
Mouse
regulation of b cell proliferationGO:0030888390.966
intrinsic apoptotic signaling pathwayGO:00971931320.965
regulation of map kinase activityGO:00434051200.963
regulation of fever generation by regulation of prostaglandin secretionGO:007181020.963
regulation of ion transportGO:00432692150.962
lymphocyte apoptotic processGO:0070227540.961
negative regulation of t cell differentiationGO:0045581230.961
cytokine metabolic processGO:0042107710.961
Mouse
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.960
Mouse
positive regulation of defense response to bacteriumGO:190042610.959
Fly
response to dsrnaGO:0043331300.957
response to lipopolysaccharideGO:00324961280.957
Mouse
calcium ion transportGO:00068161590.956
cellular amino acid metabolic processGO:00065201030.956
regulation of lipid transportGO:0032368360.955
negative regulation of apoptotic signaling pathwayGO:20012341040.955
Mouse
lymphocyte activation involved in immune responseGO:0002285930.955
Mouse
positive regulation of humoral immune responseGO:0002922110.954
Fly
response to organonitrogen compoundGO:00102432460.954
Mouse
erk1 and erk2 cascadeGO:0070371770.954
cell chemotaxisGO:0060326810.954
regulation of cellular amine metabolic processGO:0033238200.954
positive regulation of fever generationGO:003162260.952
regulation of humoral immune responseGO:0002920220.951
Fly
telencephalon developmentGO:00215371860.950
t helper 1 type immune responseGO:0042088250.946
Mouse
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.946
cell fate commitmentGO:00451652100.945
epidermis developmentGO:00085441870.942
Mouse
regulation of type 2 immune responseGO:0002828180.940
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.938
t cell chemotaxisGO:001081860.937
negative regulation of leukocyte differentiationGO:1902106510.933
t cell activation involved in immune responseGO:0002286430.932
Mouse
retinal cell programmed cell deathGO:004666680.931
leukocyte activation involved in immune responseGO:00023661260.930
Mouse
positive regulation of translationGO:0045727190.929
positive regulation of adaptive immune responseGO:0002821610.929
positive regulation of mirna metabolic processGO:200063010.928
hair cycleGO:0042633900.927
Mouse
gland developmentGO:00487323300.927
Mouse
mammary gland lobule developmentGO:0061377220.926
regulation of fever generationGO:003162060.926
regulation of transcription factor import into nucleusGO:0042990240.926
necrotic cell deathGO:0070265300.925
chronic inflammatory response to antigenic stimulusGO:000243930.924
regulation of intracellular transportGO:00323861590.923
tumor necrosis factor superfamily cytokine productionGO:0071706510.923
hair follicle developmentGO:0001942850.922
Mouse
antibacterial peptide biosynthetic processGO:000278020.922
Fly
negative regulation of alcohol biosynthetic processGO:190293140.921
programmed necrotic cell deathGO:0097300280.919
glycoprotein metabolic processGO:00091001160.918
myeloid leukocyte differentiationGO:00025731190.917
Mouse
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.916
positive regulation of ion transportGO:0043270650.915
dna metabolic processGO:00062593030.914
antigen processing and presentationGO:0019882470.912
Mouse
negative regulation of cytokine productionGO:0001818840.909
Mouse
positive regulation of programmed cell deathGO:00430682180.909
activation of jun kinase activityGO:0007257150.908
t cell apoptotic processGO:0070231390.905
liver developmentGO:0001889660.904
Mouse
regulation of antibacterial peptide biosynthetic processGO:000280810.902
Fly
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.902
circadian regulation of gene expressionGO:0032922480.900
Mouse
regulation of cytokine secretion involved in immune responseGO:000273940.897
mammary gland alveolus developmentGO:0060749220.896
somatic cell dna recombinationGO:0016444510.895
chronic inflammatory responseGO:000254490.894
regulation of t helper 1 cell differentiationGO:004562570.893
regulation of b cell activationGO:0050864810.892
response to organic cyclic compoundGO:00140701980.891
regulation of immunoglobulin mediated immune responseGO:0002889370.886
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.886
negative regulation of odontogenesis of dentin containing toothGO:004248910.885
rhythmic processGO:00485111740.883
Mouse
sensory organ morphogenesisGO:00905962420.881
regionalizationGO:00030023370.878
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.877
protein complex localizationGO:0031503190.876
positive regulation of osteoclast developmentGO:200120630.873
histamine production involved in inflammatory responseGO:000234910.872
regulation of immunoglobulin productionGO:0002637420.866
positive regulation of cd4 positive alpha beta t cell differentiationGO:0043372140.863
positive regulation of protein serine threonine kinase activityGO:00719021060.862
regulation of osteoclast differentiationGO:0045670360.860
tumor necrosis factor biosynthetic processGO:0042533100.859
glial cell apoptotic processGO:003434930.856
prostaglandin transportGO:001573270.855
regulation of myoblast differentiationGO:0045661290.855
regulation of cellular amide metabolic processGO:0034248100.853
Fly
regulation of vitamin metabolic processGO:003065630.851
polysaccharide metabolic processGO:0005976390.851
positive regulation of mapk cascadeGO:00434101700.849
neutrophil differentiationGO:003022330.849
positive regulation of lymphocyte mediated immunityGO:0002708620.849
regulation of organic acid transportGO:0032890160.847
positive regulation of production of molecular mediator of immune responseGO:0002702450.847
Fly
fatty acid derivative transportGO:1901571140.847
activation of immune responseGO:00022531380.846
positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292560.845
interleukin 12 productionGO:0032615320.844
Mouse
mapk cascadeGO:00001652810.843
positive regulation of response to biotic stimulusGO:0002833150.841
Fly
positive regulation of leukocyte proliferationGO:0070665730.840
t helper 1 cell differentiationGO:0045063130.839
Mouse
cellular response to cytokine stimulusGO:00713451890.835
regulation of oligodendrocyte differentiationGO:0048713230.834
negative regulation of interleukin 5 secretionGO:200066310.834
cellular senescenceGO:0090398110.834
regulation of inflammatory responseGO:00507271470.834
Mouse
negative regulation of molecular functionGO:00440922580.833
negative regulation of cell activationGO:00508661110.832
regulation of toll like receptor signaling pathwayGO:0034121200.832
negative regulation of protein catabolic processGO:0042177360.831
Mouse
regulation of b cell mediated immunityGO:0002712370.829
negative regulation of interleukin 13 secretionGO:200066610.825
regulation of icosanoid secretionGO:003230380.825
regulation of b cell differentiationGO:0045577230.825
negative regulation of toll like receptor signaling pathwayGO:0034122140.824
inflammatory responseGO:00069542440.823
Mouse
cytoplasmic transportGO:00164822340.821
prostaglandin secretionGO:003231050.821
regulation of fatty acid transportGO:2000191100.820
regulation of cell motilityGO:20001452360.820
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.818
negative regulation of lymphocyte differentiationGO:0045620320.817
immune response activating cell surface receptor signaling pathwayGO:0002429720.816
positive regulation of apoptotic signaling pathwayGO:2001235950.815
regulation of translational initiationGO:0006446150.814
positive regulation of hair cycleGO:004263570.811
negative regulation of immune system processGO:00026832090.809
t helper 2 cell cytokine productionGO:003574540.808
response to inorganic substanceGO:0010035960.805
mammary gland epithelial cell proliferationGO:0033598240.805
muscle cell developmentGO:00550011330.805
cytokine production involved in immune responseGO:0002367340.804
protein localization to organelleGO:00333651850.801
positive regulation of b cell proliferationGO:0030890240.801
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.800
t cell selectionGO:0045058340.800
t cell migrationGO:0072678190.799
mature b cell differentiationGO:0002335130.795
positive regulation of jnk cascadeGO:0046330460.795
interleukin 10 productionGO:0032613230.793
regulation of lymphocyte proliferationGO:00506701170.791
syncytium formation by plasma membrane fusionGO:0000768420.789
regulation of cytoplasmic transportGO:19036491120.788
regulation of striated muscle cell differentiationGO:0051153810.787
negative regulation of cellular amino acid metabolic processGO:004576300.786
natural killer cell proliferationGO:000178730.786
pigment metabolic processGO:0042440320.781
intracellular protein transportGO:00068862040.781
regulation of antimicrobial peptide biosynthetic processGO:000280510.780
Fly
lymphocyte chemotaxisGO:0048247100.779
positive regulation of t cell activationGO:00508701010.778
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.777
fever generationGO:000166070.777
oogenesisGO:0048477560.775
regulation of cytokine production involved in immune responseGO:0002718260.769
mature b cell differentiation involved in immune responseGO:000231390.768
carboxylic acid transportGO:00469421000.768
growth involved in symbiotic interactionGO:0044110230.764
b cell apoptotic processGO:0001783190.764
maintenance of locationGO:0051235890.763
negative regulation of growth of symbiont in hostGO:0044130190.763
response to amino acidGO:0043200370.750
regulation of t cell chemotaxisGO:001081950.748
jnk cascadeGO:0007254720.745
icosanoid secretionGO:0032309120.743
negative regulation of interleukin 13 productionGO:003269620.742
regulation of skeletal muscle fiber developmentGO:0048742360.740
single organism nuclear importGO:1902593950.740
hyaluronan biosynthetic processGO:003021330.740
cellular response to external stimulusGO:0071496880.739
Fly
regulation of protein localization to nucleusGO:1900180600.738
cell activation involved in immune responseGO:00022631260.738
Mouse
positive regulation of nf kappab transcription factor activityGO:0051092300.735
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.733
immunoglobulin productionGO:0002377730.732
negative regulation of regulatory t cell differentiationGO:004559020.731
regulation of kinase activityGO:00435492490.731
regulation of cell activationGO:00508652890.730
positive regulation of gamma delta t cell differentiationGO:004558860.729
positive regulation of organic acid transportGO:0032892110.725
dephosphorylationGO:00163111290.723
response to exogenous dsrnaGO:0043330220.723
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.721
regulation of alpha beta t cell proliferationGO:0046640180.717
homeostasis of number of cellsGO:00488722100.717
innate immune responseGO:00450871570.714
Fly
regulation of corticotropin releasing hormone secretionGO:004339720.714
positive regulation of immune effector processGO:00026991070.713
Fly
positive regulation of lymphocyte proliferationGO:0050671700.712
isotype switchingGO:0045190360.712
negative regulation of adaptive immune responseGO:0002820250.711
positive regulation of protein kinase b signalingGO:0051897320.711
regulation of response to biotic stimulusGO:0002831380.710
Fly
reactive oxygen species metabolic processGO:0072593840.708
positive regulation of icosanoid secretionGO:003230570.708
single organismal cell cell adhesionGO:00163371310.708
regulation of defense responseGO:00313472330.707
Mouse Fly
icosanoid transportGO:0071715140.702
stress activated mapk cascadeGO:0051403800.699
necroptotic processGO:0070266210.694
negative regulation of glucose transportGO:001082990.693
regulation of alpha beta t cell differentiationGO:0046637350.693
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.692
cation transportGO:00068123990.684
regulation of intracellular protein transportGO:0033157820.683
positive regulation of prostaglandin secretionGO:003230850.683
metal ion homeostasisGO:00550651890.682
positive regulation of interleukin 12 biosynthetic processGO:004508460.682
Mouse
regulation of cell cycleGO:00517262810.679
mammary gland epithelium developmentGO:0061180650.677
skeletal muscle organ developmentGO:00605381630.673
regulation of growth of symbiont in hostGO:0044126190.671
osteoclast developmentGO:003603590.670
branching involved in salivary gland morphogenesisGO:0060445260.669
regulation of jnk cascadeGO:0046328620.665
negative regulation of phosphatase activityGO:001092350.664
glycosaminoglycan biosynthetic processGO:0006024150.661
regulation of peptide transportGO:0090087910.661
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.659
establishment of protein localization to organelleGO:00725941180.654
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.652
antibacterial humoral responseGO:001973180.648
Fly
response to peptide hormoneGO:00434341270.647
bone resorptionGO:0045453380.647
cell fate determinationGO:0001709320.645
ossificationGO:00015032160.644
axonogenesisGO:00074092740.637
negative regulation of b cell proliferationGO:0030889130.637
pallium developmentGO:00215431200.635
monocarboxylic acid transportGO:0015718440.634
regulation of membrane potentialGO:00423911920.631
somatic diversification of immune receptorsGO:0002200530.631
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.630
regulation of anion transportGO:0044070270.628
negative regulation of interleukin 12 productionGO:0032695100.626
Mouse
regulation of organ morphogenesisGO:20000271440.624
regulation of myotube differentiationGO:0010830620.622
regulation of polysaccharide metabolic processGO:0032881130.621
carbohydrate derivative biosynthetic processGO:19011371830.619
response to tumor necrosis factorGO:0034612260.615
activation of mapk activityGO:0000187590.609
regulation of chronic inflammatory responseGO:000267670.609
positive regulation of t helper 1 cell differentiationGO:004562740.609
organic hydroxy compound metabolic processGO:19016152030.609
regulation of interferon gamma productionGO:0032649570.608
positive regulation of response to woundingGO:1903036660.604
defense response to virusGO:0051607680.602
Fly
corticotropin releasing hormone secretionGO:004339620.601
acid secretionGO:0046717330.599
defense response to gram positive bacteriumGO:0050830500.597
dendrite developmentGO:00163581150.596
Fly
type i interferon signaling pathwayGO:0060337100.594
positive regulation of cell developmentGO:00107202370.594
amine transportGO:0015837210.594
regulation of mirna metabolic processGO:200062840.591
alcohol metabolic processGO:00060661160.578
regulation of response to woundingGO:19030341890.577
Mouse
positive regulation of syncytium formation by plasma membrane fusionGO:0060143170.577
negative regulation of defense responseGO:0031348770.577
Mouse
cytokine secretion involved in immune responseGO:000237460.576
striated muscle cell developmentGO:00550021250.575
tissue remodelingGO:00487711020.573
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.573
regulation of nucleotide catabolic processGO:00308111220.572
positive regulation of intracellular protein transportGO:0090316420.572
regulation of cellular response to stressGO:00801351590.571
negative regulation of alkaline phosphatase activityGO:001069330.568
positive regulation of cysteine type endopeptidase activityGO:2001056390.568
regulation of stem cell proliferationGO:0072091780.568
Fly
divalent metal ion transportGO:00708381720.562
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.560
osteoclast differentiationGO:0030316620.552
regulation of osteoblast differentiationGO:0045667670.550
positive regulation of hair follicle developmentGO:005179860.548
protein importGO:00170381010.547
regulation of protein localizationGO:00328802310.547
regulation of lipid biosynthetic processGO:0046890540.547
regulation of stress activated mapk cascadeGO:0032872690.545
chromatin organizationGO:00063252060.545
positive regulation of protein phosphorylationGO:00019342420.541
cellular response to peptideGO:1901653920.538
gonad developmentGO:00084061410.535
thymic t cell selectionGO:0045061220.533
positive regulation of transferase activityGO:00513471670.533
regulation of mapk cascadeGO:00434082480.532
negative regulation of immune effector processGO:0002698550.532
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.532
posttranscriptional regulation of gene expressionGO:00106081550.529
positive regulation of secretionGO:00510471300.528
negative regulation of protein modification processGO:00314001630.527
response to metal ionGO:0010038470.526
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.525
muscle tissue developmentGO:00605373080.522
alpha beta t cell activationGO:0046631910.522
Mouse
epithelial cell proliferationGO:00506731740.521
positive regulation of cytokine secretion involved in immune responseGO:000274120.520
purine ribonucleoside metabolic processGO:00461282410.519
b cell receptor signaling pathwayGO:0050853200.519
mucosal associated lymphoid tissue developmentGO:0048537120.518
erythrocyte differentiationGO:0030218880.517
regulation of toll like receptor 2 signaling pathwayGO:003413530.517
covalent chromatin modificationGO:00165691630.516
tumor necrosis factor productionGO:0032640500.515
regulation of innate immune responseGO:0045088910.515
Fly

Nfkb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
primary immunodeficiency diseaseDOID:61200.860
Human
blood protein diseaseDOID:62000.860
Human
immune system diseaseDOID:291400.860
Human
agammaglobulinemiaDOID:258300.860
Human
disease of anatomical entityDOID:700.860
Human
common variable immunodeficiencyDOID:1217700.860
Human
b cell deficiencyDOID:211500.860
Human
hematopoietic system diseaseDOID:7400.860
Human
musculoskeletal system diseaseDOID:1700.763
connective tissue diseaseDOID:6500.763
bone remodeling diseaseDOID:008000500.662
bone diseaseDOID:008000100.662
osteopetrosisDOID:1353300.662
osteosclerosisDOID:425400.662