IMP: Integrative Multi-species Prediction

Mus musculus

148 known processes

Ptgir

prostaglandin I receptor (IP)

(Aliases: IP,PGI2)

Entrez: 19222
Ensembl: ENSMUSG00000043017
UniProtKB: P43252
UniProtKB: Q8CC99

Process Predictions
Disease Predictions

Ptgir biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of inflammatory response	GO:0050727	147	0.829	Mouse
leukocyte mediated immunity	GO:0002443	174	0.795
adaptive immune response	GO:0002250	155	0.736
leukocyte migration	GO:0050900	124	0.721
immune effector process	GO:0002252	321	0.677	Mouse
cytokine production	GO:0001816	319	0.670	Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.637
multicellular organismal homeostasis	GO:0048871	164	0.605	Mouse
myeloid leukocyte differentiation	GO:0002573	119	0.576
g protein coupled receptor signaling pathway	GO:0007186	243	0.566
regulation of defense response	GO:0031347	233	0.565	Mouse
regulation of cell motility	GO:2000145	236	0.547
defense response to other organism	GO:0098542	197	0.534
smooth muscle contraction	GO:0006939	44	0.531	Mouse
inflammatory response	GO:0006954	244	0.529	Mouse
cation transport	GO:0006812	399	0.495
regulation of kinase activity	GO:0043549	249	0.489
negative regulation of inflammatory response	GO:0050728	61	0.459	Mouse
chemotaxis	GO:0006935	247	0.454
regulation of response to wounding	GO:1903034	189	0.443	Mouse
organonitrogen compound biosynthetic process	GO:1901566	192	0.433
response to lipopolysaccharide	GO:0032496	128	0.416
cellular response to cytokine stimulus	GO:0071345	189	0.390
calcium ion transport	GO:0006816	159	0.390
positive regulation of cytokine production	GO:0001819	174	0.383	Mouse
positive regulation of protein secretion	GO:0050714	52	0.380	Mouse
cd4 positive alpha beta t cell activation	GO:0035710	45	0.379	Mouse
regulation of ossification	GO:0030278	112	0.377	Mouse
ras protein signal transduction	GO:0007265	77	0.375
lymphocyte mediated immunity	GO:0002449	139	0.363
regulation of leukocyte mediated immunity	GO:0002703	104	0.360
glycosyl compound metabolic process	GO:1901657	246	0.359	Mouse
regulation of cell migration	GO:0030334	219	0.358
regulation of cellular amine metabolic process	GO:0033238	20	0.352
positive regulation of cytokine secretion	GO:0050715	41	0.342	Mouse
positive regulation of defense response	GO:0031349	124	0.339	Mouse
alpha beta t cell activation involved in immune response	GO:0002287	31	0.326	Mouse
response to molecule of bacterial origin	GO:0002237	143	0.324
protein secretion	GO:0009306	111	0.320	Mouse
cellular homeostasis	GO:0019725	240	0.316	Mouse
positive regulation of leukocyte differentiation	GO:1902107	86	0.310
positive regulation of cell death	GO:0010942	224	0.306
regulation of protein secretion	GO:0050708	82	0.306	Mouse
cell killing	GO:0001906	67	0.305
t cell proliferation	GO:0042098	120	0.304
negative regulation of phosphate metabolic process	GO:0045936	184	0.303
negative regulation of response to wounding	GO:1903035	77	0.303	Mouse
negative regulation of defense response	GO:0031348	77	0.303	Mouse
blood vessel morphogenesis	GO:0048514	285	0.301
regulation of secretion by cell	GO:1903530	249	0.296	Mouse
positive regulation of protein modification process	GO:0031401	299	0.286
regulation of lymphocyte proliferation	GO:0050670	117	0.278
regulation of ion homeostasis	GO:2000021	64	0.270
regulation of cytokine secretion	GO:0050707	61	0.264	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.264
regulation of mapk cascade	GO:0043408	248	0.263
cd4 positive alpha beta t cell differentiation involved in immune response	GO:0002294	28	0.263	Mouse
transmembrane transport	GO:0055085	412	0.263
purine containing compound metabolic process	GO:0072521	311	0.262
myeloid cell differentiation	GO:0030099	233	0.261
cation transmembrane transport	GO:0098655	266	0.259
organic acid transport	GO:0015849	101	0.258
regulation of cell activation	GO:0050865	289	0.258
organic anion transport	GO:0015711	137	0.254	Mouse
cellular response to lipopolysaccharide	GO:0071222	77	0.251
regulation of smooth muscle contraction	GO:0006940	22	0.250	Mouse
regulation of adaptive immune response	GO:0002819	90	0.248
alpha beta t cell differentiation	GO:0046632	69	0.247	Mouse
ceramide biosynthetic process	GO:0046513	20	0.246
anion transport	GO:0006820	177	0.245	Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.244
cellular ketone metabolic process	GO:0042180	84	0.243
positive regulation of protein phosphorylation	GO:0001934	242	0.243
purine nucleotide metabolic process	GO:0006163	302	0.242
granulocyte chemotaxis	GO:0071621	39	0.237
amino acid transport	GO:0006865	61	0.236
positive regulation of nucleotide metabolic process	GO:0045981	114	0.233
response to transforming growth factor beta	GO:0071559	88	0.231
circulatory system process	GO:0003013	197	0.231	Mouse
dendritic cell differentiation	GO:0097028	26	0.225
cellular metal ion homeostasis	GO:0006875	151	0.225	Mouse
leukocyte proliferation	GO:0070661	172	0.220
negative regulation of immune system process	GO:0002683	209	0.218
ribonucleotide catabolic process	GO:0009261	208	0.218
gtp catabolic process	GO:0006184	143	0.216
muscle cell differentiation	GO:0042692	261	0.216
urogenital system development	GO:0001655	261	0.215
cellular response to biotic stimulus	GO:0071216	92	0.215
regulation of ion transport	GO:0043269	215	0.211
cytokine mediated signaling pathway	GO:0019221	115	0.209
regulation of map kinase activity	GO:0043405	120	0.209
regulation of neuron projection development	GO:0010975	169	0.207
cellular calcium ion homeostasis	GO:0006874	119	0.206	Mouse
muscle tissue development	GO:0060537	308	0.206
nitrogen compound transport	GO:0071705	271	0.203
regulation of protein transport	GO:0051223	163	0.201	Mouse
positive regulation of behavior	GO:0048520	40	0.200
mapk cascade	GO:0000165	281	0.199
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.198
divalent inorganic cation transport	GO:0072511	178	0.196
regulation of cellular component biogenesis	GO:0044087	181	0.192	Mouse
ion transmembrane transport	GO:0034220	361	0.192
ossification	GO:0001503	216	0.190	Mouse
wound healing	GO:0042060	157	0.185
myeloid leukocyte migration	GO:0097529	57	0.184
lymphocyte differentiation	GO:0030098	242	0.183	Mouse
angiogenesis	GO:0001525	201	0.182
tumor necrosis factor superfamily cytokine production	GO:0071706	51	0.182
positive regulation of chemotaxis	GO:0050921	38	0.182
negative regulation of cell migration	GO:0030336	59	0.182
cellular response to molecule of bacterial origin	GO:0071219	83	0.180
regulation of leukocyte proliferation	GO:0070663	121	0.176
regulation of cellular response to stress	GO:0080135	159	0.175
guanosine containing compound catabolic process	GO:1901069	144	0.173
leukocyte activation involved in immune response	GO:0002366	126	0.172	Mouse
mature dendritic cell differentiation	GO:0097029	3	0.172
leukocyte chemotaxis	GO:0030595	69	0.171
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	30	0.169
cell type specific apoptotic process	GO:0097285	268	0.169
regulation of cytokine production	GO:0001817	266	0.166	Mouse
cell chemotaxis	GO:0060326	81	0.166
ribonucleotide metabolic process	GO:0009259	291	0.161
innate immune response	GO:0045087	157	0.161
positive regulation of leukocyte mediated immunity	GO:0002705	70	0.160
b cell mediated immunity	GO:0019724	71	0.159
negative regulation of protein modification process	GO:0031400	163	0.158
cellular response to prostaglandin d stimulus	GO:0071799	1	0.158	Mouse
positive regulation of monocyte chemotaxis	GO:0090026	2	0.156
myeloid leukocyte activation	GO:0002274	83	0.156
rho protein signal transduction	GO:0007266	32	0.155
regulation of cell projection organization	GO:0031344	206	0.153
stem cell differentiation	GO:0048863	268	0.151
defense response to bacterium	GO:0042742	119	0.151
t cell activation	GO:0042110	289	0.147	Mouse
alpha beta t cell activation	GO:0046631	91	0.146	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	247	0.146
alpha beta t cell proliferation	GO:0046633	21	0.144
regulation of transferase activity	GO:0051338	263	0.143
regulation of lymphocyte activation	GO:0051249	240	0.143
positive regulation of kinase activity	GO:0033674	155	0.142
interleukin 12 secretion	GO:0072610	3	0.142
positive regulation of cell motility	GO:2000147	116	0.142
carbohydrate derivative biosynthetic process	GO:1901137	183	0.142
apoptotic signaling pathway	GO:0097190	306	0.139
skeletal system morphogenesis	GO:0048705	203	0.139
coagulation	GO:0050817	78	0.138
regulation of hydrolase activity	GO:0051336	246	0.136
granulocyte migration	GO:0097530	43	0.135
sensory perception	GO:0007600	245	0.135
synapse organization	GO:0050808	125	0.134
helper t cell chemotaxis	GO:0035704	1	0.133
membrane lipid biosynthetic process	GO:0046467	32	0.133
lymphocyte proliferation	GO:0046651	164	0.132
guanosine containing compound metabolic process	GO:1901068	144	0.132
axonogenesis	GO:0007409	274	0.132
blood coagulation	GO:0007596	76	0.131
cell adhesion	GO:0007155	329	0.131
amine metabolic process	GO:0009308	45	0.129
regulation of homeostatic process	GO:0032844	182	0.129	Mouse
regulation of anatomical structure size	GO:0090066	178	0.129	Mouse
positive regulation of ion transport	GO:0043270	65	0.127
sensory organ morphogenesis	GO:0090596	242	0.126
regulation of system process	GO:0044057	200	0.126	Mouse
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.126
negative regulation of growth	GO:0045926	99	0.124
metal ion homeostasis	GO:0055065	189	0.124	Mouse
positive regulation of leukocyte proliferation	GO:0070665	73	0.123
positive regulation of hydrolase activity	GO:0051345	148	0.123
killing by host of symbiont cells	GO:0051873	11	0.123
divalent metal ion transport	GO:0070838	172	0.123
regulation of cellular ketone metabolic process	GO:0010565	66	0.123
glycosyl compound catabolic process	GO:1901658	206	0.122
cytokine secretion	GO:0050663	72	0.122	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.122
purine ribonucleotide catabolic process	GO:0009154	208	0.121
synaptic transmission	GO:0007268	329	0.121
multicellular organism growth	GO:0035264	161	0.121
regulation of thymocyte migration	GO:2000410	2	0.120
platelet activation	GO:0030168	40	0.120
regulation of lymphocyte mediated immunity	GO:0002706	84	0.120
positive regulation of eosinophil migration	GO:2000418	2	0.119
positive regulation of thymocyte migration	GO:2000412	2	0.117
cytosolic calcium ion homeostasis	GO:0051480	70	0.116	Mouse
sphingolipid metabolic process	GO:0006665	45	0.116
regulation of innate immune response	GO:0045088	91	0.116
purinergic nucleotide receptor signaling pathway	GO:0035590	3	0.116
kidney development	GO:0001822	213	0.115
extrinsic apoptotic signaling pathway	GO:0097191	126	0.115
ribose phosphate metabolic process	GO:0019693	291	0.114
cellular lipid metabolic process	GO:0044255	323	0.113
regulation of nucleotide metabolic process	GO:0006140	169	0.113
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.112
regulation of multi organism process	GO:0043900	111	0.111
t helper cell differentiation	GO:0042093	28	0.111	Mouse
regulation of synaptic plasticity	GO:0048167	87	0.110
positive regulation of gtp catabolic process	GO:0033126	85	0.110
divalent inorganic cation homeostasis	GO:0072507	138	0.109	Mouse
positive regulation of secretion	GO:0051047	130	0.108	Mouse
sphingolipid biosynthetic process	GO:0030148	26	0.108
response to radiation	GO:0009314	165	0.108
nucleoside catabolic process	GO:0009164	206	0.107
regulation of cell adhesion	GO:0030155	154	0.106
positive regulation of immune effector process	GO:0002699	107	0.106
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.106
positive regulation of cell activation	GO:0050867	158	0.106
positive regulation of secretion by cell	GO:1903532	114	0.105	Mouse
thymocyte migration	GO:0072679	2	0.104
learning	GO:0007612	98	0.102
purine containing compound catabolic process	GO:0072523	213	0.102
acute inflammatory response	GO:0002526	41	0.101	Mouse
axon guidance	GO:0007411	141	0.101
regulation of alpha beta t cell activation	GO:0046634	53	0.101
macromolecule catabolic process	GO:0009057	281	0.100
t cell differentiation	GO:0030217	174	0.098	Mouse
cellular ion homeostasis	GO:0006873	165	0.097	Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.097
positive regulation of apoptotic process	GO:0043065	217	0.097
superoxide metabolic process	GO:0006801	27	0.097
blood circulation	GO:0008015	195	0.096	Mouse
positive regulation of cell migration	GO:0030335	109	0.096
gtp metabolic process	GO:0046039	144	0.095
regulation of leukocyte differentiation	GO:1902105	159	0.095
positive regulation of cell development	GO:0010720	237	0.095
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.094
regulation of gamma aminobutyric acid secretion	GO:0014052	2	0.093
protein catabolic process	GO:0030163	221	0.093
regulation of blood circulation	GO:1903522	93	0.092	Mouse
regulation of protein kinase activity	GO:0045859	232	0.092
t helper 1 type immune response	GO:0042088	25	0.091
regulation of monocyte chemotaxis	GO:0090025	3	0.091
negative regulation of kinase activity	GO:0033673	81	0.091
positive regulation of nervous system development	GO:0051962	221	0.091
connective tissue development	GO:0061448	179	0.091
regulation of body fluid levels	GO:0050878	162	0.090	Mouse
regulation of protein catabolic process	GO:0042176	108	0.090
interleukin 6 production	GO:0032635	58	0.090
negative regulation of protein metabolic process	GO:0051248	282	0.089
immune complex clearance	GO:0002434	2	0.088
sequestering of metal ion	GO:0051238	19	0.088
regulation of gtp catabolic process	GO:0033124	113	0.088
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.088
stem cell development	GO:0048864	219	0.088
interleukin 1 production	GO:0032612	31	0.087
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.087
t cell mediated immunity	GO:0002456	50	0.087
muscle system process	GO:0003012	141	0.086	Mouse
immunoglobulin mediated immune response	GO:0016064	69	0.086
regulation of muscle contraction	GO:0006937	49	0.085	Mouse
positive regulation of protein transport	GO:0051222	93	0.084	Mouse
positive regulation of syncytium formation by plasma membrane fusion	GO:0060143	17	0.084
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.084	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.084
regulation of proteolysis	GO:0030162	164	0.083
regulation of neuron differentiation	GO:0045664	281	0.083
regulation of cellular amino acid metabolic process	GO:0006521	5	0.083
cell activation involved in immune response	GO:0002263	126	0.082	Mouse
defense response to gram negative bacterium	GO:0050829	28	0.082
positive regulation of inflammatory response	GO:0050729	47	0.082	Mouse
negative regulation of secretion	GO:0051048	61	0.081	Mouse
ceramide metabolic process	GO:0006672	31	0.080
associative learning	GO:0008306	61	0.080
negative regulation of phosphorylation	GO:0042326	166	0.080
positive regulation of mapk cascade	GO:0043410	170	0.080
dna metabolic process	GO:0006259	303	0.080
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.080
response to organic cyclic compound	GO:0014070	198	0.079
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.079
ribonucleoside metabolic process	GO:0009119	245	0.079	Mouse
reactive oxygen species metabolic process	GO:0072593	84	0.079
lymphocyte activation involved in immune response	GO:0002285	93	0.079	Mouse
cellular chemical homeostasis	GO:0055082	215	0.078	Mouse
nucleoside triphosphate metabolic process	GO:0009141	230	0.078
t cell extravasation	GO:0072683	4	0.078
striated muscle tissue development	GO:0014706	293	0.078
leukocyte differentiation	GO:0002521	342	0.078	Mouse
response to growth factor	GO:0070848	198	0.077
tissue remodeling	GO:0048771	102	0.077
positive regulation of glutamate secretion	GO:0014049	2	0.077
i kappab kinase nf kappab signaling	GO:0007249	85	0.077
regulation of rho protein signal transduction	GO:0035023	71	0.076
carbohydrate derivative catabolic process	GO:1901136	231	0.076
regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling	GO:0003027	1	0.076
platelet derived growth factor receptor signaling pathway	GO:0048008	32	0.076
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.075
ribonucleoside catabolic process	GO:0042454	206	0.075
negative regulation of cell activation	GO:0050866	111	0.074
carbohydrate transport	GO:0008643	62	0.074
positive regulation of immunological synapse formation	GO:2000522	1	0.074
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.074
homeostasis of number of cells	GO:0048872	210	0.074
positive regulation of lymphocyte proliferation	GO:0050671	70	0.074
response to organonitrogen compound	GO:0010243	246	0.074
phospholipid transfer to membrane	GO:0006649	2	0.073
methylation	GO:0032259	134	0.073
monoamine transport	GO:0015844	33	0.073
negative regulation of phosphorus metabolic process	GO:0010563	184	0.072
positive regulation of programmed cell death	GO:0043068	218	0.072
negative regulation of mapk cascade	GO:0043409	65	0.072
regulation of ras protein signal transduction	GO:0046578	114	0.072
monocarboxylic acid metabolic process	GO:0032787	191	0.072
detection of stimulus	GO:0051606	84	0.072
negative regulation of cellular component organization	GO:0051129	194	0.072
negative regulation of cell proliferation	GO:0008285	296	0.071
ribose phosphate biosynthetic process	GO:0046390	59	0.071
regulation of chemotaxis	GO:0050920	53	0.071
regulation of vasculature development	GO:1901342	88	0.071
interleukin 1 secretion	GO:0050701	16	0.071
locomotory behavior	GO:0007626	195	0.071
jnk cascade	GO:0007254	72	0.070
regulation of chemokine production	GO:0032642	30	0.070
cation homeostasis	GO:0055080	212	0.070	Mouse
regulation of b cell proliferation	GO:0030888	39	0.070
nucleobase containing small molecule metabolic process	GO:0055086	352	0.069
camp metabolic process	GO:0046058	40	0.069
purine ribonucleotide metabolic process	GO:0009150	290	0.069
response to acid chemical	GO:0001101	111	0.068	Mouse
regulation of protein localization	GO:0032880	231	0.068	Mouse
positive regulation of gtpase activity	GO:0043547	85	0.068
membrane depolarization	GO:0051899	64	0.068
regulation of monocyte extravasation	GO:2000437	2	0.068
regulation of glutamate secretion	GO:0014048	3	0.068
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.068
myotube differentiation	GO:0014902	105	0.068
negative regulation of cytokine production	GO:0001818	84	0.068	Mouse
calcium ion homeostasis	GO:0055074	127	0.067	Mouse
regulation of anion transport	GO:0044070	27	0.067
aromatic compound catabolic process	GO:0019439	286	0.066
regulation of secretion	GO:0051046	274	0.066	Mouse
regulation of cell cycle	GO:0051726	281	0.066
positive regulation of transferase activity	GO:0051347	167	0.066
positive regulation of t cell receptor signaling pathway	GO:0050862	4	0.066
positive regulation of epithelial cell proliferation	GO:0050679	68	0.065
cytosolic calcium ion transport	GO:0060401	48	0.065
eosinophil migration	GO:0072677	3	0.065
monocarboxylic acid transport	GO:0015718	44	0.065
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.065	Mouse
positive regulation of cellular component biogenesis	GO:0044089	94	0.064
nucleoside triphosphate catabolic process	GO:0009143	205	0.064
cellular response to lipid	GO:0071396	145	0.064	Mouse
circadian rhythm	GO:0007623	114	0.064
actin cytoskeleton organization	GO:0030036	220	0.064	Mouse
reactive nitrogen species metabolic process	GO:2001057	0	0.064
immune response activating signal transduction	GO:0002757	116	0.063
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.063
regulation of blood pressure	GO:0008217	93	0.063
regulation of circadian rhythm	GO:0042752	58	0.063
gland development	GO:0048732	330	0.062
regulation of blood vessel size	GO:0050880	56	0.062	Mouse
regulation of vesicle mediated transport	GO:0060627	139	0.062
negative regulation of platelet derived growth factor receptor signaling pathway	GO:0010642	7	0.061
negative regulation of nervous system development	GO:0051961	156	0.061
bone resorption	GO:0045453	38	0.061
regulation of protein serine threonine kinase activity	GO:0071900	157	0.061
cell growth	GO:0016049	130	0.061
immunoglobulin production involved in immunoglobulin mediated immune response	GO:0002381	43	0.061
bone development	GO:0060348	120	0.061
regulation of voltage gated calcium channel activity	GO:1901385	4	0.061
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	50	0.061
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.061
organelle localization	GO:0051640	179	0.060
regulation of cellular component size	GO:0032535	121	0.060
forebrain development	GO:0030900	302	0.060
feeding behavior	GO:0007631	62	0.060
negative regulation of t helper 2 cell differentiation	GO:0045629	4	0.060
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	GO:2000526	1	0.060
gliogenesis	GO:0042063	141	0.060
response to decreased oxygen levels	GO:0036293	59	0.059
sequestering of calcium ion	GO:0051208	18	0.059
immune complex clearance by monocytes and macrophages	GO:0002436	2	0.059
purine ribonucleoside metabolic process	GO:0046128	241	0.059	Mouse
conditioned taste aversion	GO:0001661	4	0.059
negative regulation of intracellular signal transduction	GO:1902532	167	0.059
glucose homeostasis	GO:0042593	128	0.058
fat cell differentiation	GO:0045444	160	0.058
positive regulation of t helper 1 cell differentiation	GO:0045627	4	0.058
response to oxidative stress	GO:0006979	123	0.058
regulation of platelet derived growth factor receptor signaling pathway	GO:0010640	9	0.058
regulation of fat cell differentiation	GO:0045598	81	0.058
positive regulation of protein kinase activity	GO:0045860	144	0.057
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.057
spleen development	GO:0048536	39	0.057
oxidation reduction process	GO:0055114	342	0.057
regulation of vascular smooth muscle contraction	GO:0003056	1	0.057
carboxylic acid transport	GO:0046942	100	0.057
regulation of cellular catabolic process	GO:0031329	242	0.057
leukocyte apoptotic process	GO:0071887	71	0.057
branching morphogenesis of an epithelial tube	GO:0048754	159	0.056
regulation of t cell proliferation	GO:0042129	92	0.056
eosinophil activation	GO:0043307	1	0.055
positive regulation of interleukin 12 production	GO:0032735	21	0.054
cellular amine metabolic process	GO:0044106	44	0.054
regulation of membrane potential	GO:0042391	192	0.054
regulation of striated muscle cell differentiation	GO:0051153	81	0.054
cytoplasmic transport	GO:0016482	234	0.054
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.054
positive regulation of response to wounding	GO:1903036	66	0.054	Mouse
nucleotide metabolic process	GO:0009117	332	0.054
regulation of mast cell activation involved in immune response	GO:0033006	17	0.053
regulation of t cell activation	GO:0050863	170	0.053
regulation of organelle organization	GO:0033043	289	0.053	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.053
anatomical structure homeostasis	GO:0060249	145	0.052
regulation of interleukin 6 production	GO:0032675	55	0.052
hemostasis	GO:0007599	78	0.052
regulation of interleukin 1 production	GO:0032652	26	0.052
regulation of establishment of protein localization	GO:0070201	181	0.052	Mouse
monocyte extravasation	GO:0035696	2	0.052
leukocyte mediated cytotoxicity	GO:0001909	62	0.051
phospholipase c activating g protein coupled receptor signaling pathway	GO:0007200	26	0.051	Mouse
leukocyte homeostasis	GO:0001776	79	0.051
defense response to virus	GO:0051607	68	0.051
positive regulation of alpha beta t cell activation	GO:0046635	39	0.051
heterocycle catabolic process	GO:0046700	280	0.051
regulation of immune complex clearance by monocytes and macrophages	GO:0090264	2	0.051
respiratory tube development	GO:0030323	167	0.051
cartilage development	GO:0051216	140	0.051
regulation of muscle system process	GO:0090257	80	0.050	Mouse
tendon formation	GO:0035992	4	0.050
positive regulation of alpha beta t cell differentiation	GO:0046638	28	0.050
organic cyclic compound catabolic process	GO:1901361	295	0.050
response to inorganic substance	GO:0010035	96	0.050
positive regulation of monocyte extravasation	GO:2000439	1	0.050
epithelial cell proliferation	GO:0050673	174	0.050
organ growth	GO:0035265	117	0.050
transmission of nerve impulse	GO:0019226	76	0.050
myeloid leukocyte mediated immunity	GO:0002444	42	0.050
positive regulation of lymphocyte differentiation	GO:0045621	61	0.049
negative regulation of protein phosphorylation	GO:0001933	126	0.049
positive regulation of jun kinase activity	GO:0043507	30	0.049
positive regulation of glial cell proliferation	GO:0060252	4	0.049
forebrain cell migration	GO:0021885	58	0.049
positive regulation of neuron differentiation	GO:0045666	141	0.049
endochondral bone morphogenesis	GO:0060350	50	0.049
inflammatory response to antigenic stimulus	GO:0002437	30	0.049
positive regulation of cell killing	GO:0031343	33	0.048
mammary gland morphogenesis	GO:0060443	54	0.048
regulation of cytolysis	GO:0042268	1	0.048
myeloid dendritic cell differentiation	GO:0043011	16	0.048
myeloid dendritic cell activation	GO:0001773	25	0.048
negative regulation of cell motility	GO:2000146	61	0.048
neutrophil migration	GO:1990266	37	0.048
membrane lipid metabolic process	GO:0006643	53	0.048
nucleoside metabolic process	GO:0009116	246	0.048	Mouse
negative regulation of cellular amine metabolic process	GO:0033239	1	0.048
regulation of t helper 1 type immune response	GO:0002825	17	0.048
glucose transport	GO:0015758	56	0.047
bone morphogenesis	GO:0060349	78	0.047
biomineral tissue development	GO:0031214	64	0.047
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.046
membrane organization	GO:0061024	245	0.046
skeletal system development	GO:0001501	356	0.046
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.046
nucleoside phosphate metabolic process	GO:0006753	338	0.046
cognition	GO:0050890	149	0.046
tumor necrosis factor production	GO:0032640	50	0.046
developmental growth involved in morphogenesis	GO:0060560	138	0.046
lipoxin a4 biosynthetic process	GO:2001303	1	0.046
positive regulation of cellular catabolic process	GO:0031331	148	0.046
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.046
syncytium formation by plasma membrane fusion	GO:0000768	42	0.046
positive regulation of map kinase activity	GO:0043406	84	0.046
morphogenesis of a branching epithelium	GO:0061138	193	0.045
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.045
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.045
cerebral cortex cell migration	GO:0021795	44	0.045
positive regulation of camp mediated signaling	GO:0043950	3	0.045
regulation of feeding behavior	GO:0060259	3	0.045
negative regulation of lymphocyte proliferation	GO:0050672	45	0.045
regulation of nucleotide catabolic process	GO:0030811	122	0.045
positive regulation of dendritic cell dendrite assembly	GO:2000549	1	0.045
regulation of transmembrane transport	GO:0034762	128	0.044
organophosphate biosynthetic process	GO:0090407	122	0.044
regulation of protein complex assembly	GO:0043254	83	0.044
cyclic nucleotide biosynthetic process	GO:0009190	44	0.044
purine nucleotide catabolic process	GO:0006195	211	0.044
regulation of interleukin 1 alpha production	GO:0032650	4	0.044
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.044	Mouse
cellular response to growth factor stimulus	GO:0071363	197	0.044
cardiac epithelial to mesenchymal transition	GO:0060317	18	0.044
astrocyte fate commitment	GO:0060018	4	0.044
regulation of apoptotic signaling pathway	GO:2001233	197	0.043
muscle fiber development	GO:0048747	76	0.043
histone modification	GO:0016570	159	0.043
positive regulation of synaptic plasticity	GO:0031915	4	0.043
activation of mapk activity	GO:0000187	59	0.043
regulation of alpha beta t cell proliferation	GO:0046640	18	0.043
neutrophil mediated immunity	GO:0002446	19	0.043
regulation of myotube differentiation	GO:0010830	62	0.043
ameboidal type cell migration	GO:0001667	128	0.043
skeletal muscle fiber development	GO:0048741	58	0.043
intracellular receptor signaling pathway	GO:0030522	74	0.043
t helper 17 cell chemotaxis	GO:0035705	1	0.042
vascular process in circulatory system	GO:0003018	62	0.042	Mouse
tube closure	GO:0060606	91	0.042
positive regulation of homeostatic process	GO:0032846	64	0.042	Mouse
positive regulation of inner ear receptor cell differentiation	GO:2000982	1	0.042
organonitrogen compound catabolic process	GO:1901565	264	0.042
calcium ion transport into cytosol	GO:0060402	48	0.042
action potential	GO:0001508	78	0.042
regulation of interleukin 1 beta production	GO:0032651	25	0.041

Ptgir disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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