Mus musculus

62 known processes

Parl

presenilin associated, rhomboid-like

(Aliases: PRO2207,PSENIP2,Psarl,D16Ertd607e,PSARL1)

Parl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrion organizationGO:00070051340.419
iron sulfur cluster assemblyGO:001622630.327
mitochondrial fusionGO:000805390.192
Fly
purine ribonucleoside metabolic processGO:00461282410.184
neural tube formationGO:00018411080.181
nucleoside metabolic processGO:00091162460.164
purine ribonucleotide metabolic processGO:00091502900.162
embryonic epithelial tube formationGO:00018381300.137
ribonucleotide metabolic processGO:00092592910.133
nucleoside triphosphate metabolic processGO:00091412300.128
ribose phosphate metabolic processGO:00196932910.121
nucleobase containing small molecule metabolic processGO:00550863520.118
organophosphate biosynthetic processGO:00904071220.096
morphogenesis of embryonic epitheliumGO:00163311590.095
modification dependent macromolecule catabolic processGO:00436321330.092
purine ribonucleoside triphosphate metabolic processGO:00092052200.089
purine containing compound metabolic processGO:00725213110.086
proteasomal ubiquitin independent protein catabolic processGO:001049910.083
neural tube developmentGO:00219151600.080
positive regulation of membrane potentialGO:0045838150.077
nucleotide metabolic processGO:00091173320.076
coenzyme biosynthetic processGO:0009108230.075
cellular protein catabolic processGO:00442571550.075
nucleoside phosphate metabolic processGO:00067533380.075
mitochondrion morphogenesisGO:0070584130.073
glycosyl compound metabolic processGO:19016572460.069
metallo sulfur cluster assemblyGO:003116330.067
proteasome assemblyGO:004324810.064
stem cell differentiationGO:00488632680.063
gonad developmentGO:00084061410.062
purine nucleotide metabolic processGO:00061633020.061
glycerophospholipid metabolic processGO:0006650710.059
membrane organizationGO:00610242450.059
Fly
tube formationGO:00351481400.057
cellular ketone metabolic processGO:0042180840.051
methylationGO:00322591340.050
transmembrane transportGO:00550854120.049
protein catabolic processGO:00301632210.048
ribonucleotide biosynthetic processGO:0009260590.048
lipid biosynthetic processGO:00086101790.048
cellular macromolecule catabolic processGO:00442652060.047
neural tube closureGO:0001843900.047
purine nucleotide biosynthetic processGO:0006164650.047
ribose phosphate biosynthetic processGO:0046390590.046
epithelial tube formationGO:00721751300.046
ribonucleoside monophosphate metabolic processGO:0009161800.045
cofactor metabolic processGO:0051186800.044
purine ribonucleotide biosynthetic processGO:0009152590.044
ribonucleotide catabolic processGO:00092612080.043
proteasomal protein catabolic processGO:0010498980.040
purine nucleoside metabolic processGO:00422782410.040
trna wobble uridine modificationGO:000209820.039
nucleoside phosphate biosynthetic processGO:1901293790.039
purine nucleotide catabolic processGO:00061952110.039
cellular lipid metabolic processGO:00442553230.038
regulation of cellular amine metabolic processGO:0033238200.038
epithelial tube morphogenesisGO:00605623030.037
regulation of nucleotide metabolic processGO:00061401690.037
purine nucleoside triphosphate metabolic processGO:00091442260.037
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.037
sulfur compound metabolic processGO:00067901000.037
aromatic compound catabolic processGO:00194392860.036
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.036
purine ribonucleoside monophosphate metabolic processGO:0009167800.034
ribonucleoside metabolic processGO:00091192450.034
development of primary sexual characteristicsGO:00451371430.034
endocytosisGO:00068971680.034
macromolecule catabolic processGO:00090572810.033
ubiquitin dependent protein catabolic processGO:00065111290.033
cation transmembrane transportGO:00986552660.033
small molecule biosynthetic processGO:00442831320.032
cellular amine metabolic processGO:0044106440.032
inorganic ion transmembrane transportGO:00986602340.031
ribonucleoside monophosphate biosynthetic processGO:000915690.030
organelle fusionGO:0048284280.030
Fly
organonitrogen compound biosynthetic processGO:19015661920.030
spermatogenesisGO:00072832840.030
amine metabolic processGO:0009308450.030
ion transmembrane transportGO:00342203610.030
cellular homeostasisGO:00197252400.030
regulation of phospholipid biosynthetic processGO:007107130.030
proteolysis involved in cellular protein catabolic processGO:00516031470.029
nucleoside triphosphate catabolic processGO:00091432050.029
heterocycle catabolic processGO:00467002800.029
nucleoside monophosphate metabolic processGO:0009123850.029
organic cyclic compound catabolic processGO:19013612950.029
cellular amino acid metabolic processGO:00065201030.028
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.028
cofactor biosynthetic processGO:0051188410.028
rna processingGO:00063961050.028
ribonucleoside triphosphate metabolic processGO:00091992200.028
cellular response to dna damage stimulusGO:00069742070.027
skeletal system developmentGO:00015013560.027
regulation of nucleoside metabolic processGO:00091181300.027
negative regulation of intracellular signal transductionGO:19025321670.027
ossificationGO:00015032160.027
purine nucleoside monophosphate metabolic processGO:0009126810.027
purine containing compound biosynthetic processGO:0072522700.027
regulation of purine nucleotide catabolic processGO:00331211220.026
macromolecule methylationGO:00434141200.026
mitotic cytokinesisGO:000028140.026
phospholipid metabolic processGO:0006644870.026
coenzyme metabolic processGO:0006732520.025
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.025
regulation of hydrolase activityGO:00513362460.025
carbohydrate derivative catabolic processGO:19011362310.025
t cell activationGO:00421102890.025
cristae formationGO:004240730.025
modification dependent protein catabolic processGO:00199411330.025
nucleoside monophosphate biosynthetic processGO:0009124120.024
purine nucleoside triphosphate catabolic processGO:00091462030.024
regulation of protein modification by small protein conjugation or removalGO:1903320570.024
regulation of purine nucleotide metabolic processGO:19005421690.023
organophosphate catabolic processGO:00464342320.023
guanosine containing compound metabolic processGO:19010681440.023
carbohydrate derivative biosynthetic processGO:19011371830.022
negative regulation of mitochondrion organizationGO:001082390.022
membrane fusionGO:0061025380.021
Fly
regulation of cellular component biogenesisGO:00440871810.021
negative regulation of cellular amine metabolic processGO:003323910.021
inner mitochondrial membrane organizationGO:000700750.021
cation homeostasisGO:00550802120.021
cellularizationGO:000734910.021
positive regulation of protein modification processGO:00314012990.020
regulation of cell cycle processGO:00105641600.020
calcium ion homeostasisGO:00550741270.020
primary neural tube formationGO:0014020950.020
germ cell developmentGO:00072811850.019
regulation of cellular amino acid metabolic processGO:000652150.019
divalent metal ion transportGO:00708381720.019
nucleotide catabolic processGO:00091662170.019
regulation of transmembrane transportGO:00347621280.019
epithelial cell proliferationGO:00506731740.018
positive regulation of nucleoside metabolic processGO:0045979910.018
gtp catabolic processGO:00061841430.018
nitrogen compound transportGO:00717052710.018
apoptotic mitochondrial changesGO:0008637480.017
cardiolipin metabolic processGO:003204830.017
alcohol metabolic processGO:00060661160.017
positive regulation of hydrolase activityGO:00513451480.017
divalent inorganic cation transportGO:00725111780.017
mitochondrial genome maintenanceGO:0000002150.017
purine containing compound catabolic processGO:00725232130.017
inorganic cation transmembrane transportGO:00986622070.017
response to inorganic substanceGO:0010035960.017
response to oxidative stressGO:00069791230.016
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.016
endomembrane system organizationGO:00102561470.016
glycerolipid metabolic processGO:00464861220.016
antigen receptor mediated signaling pathwayGO:0050851640.016
cellular protein complex assemblyGO:00436231160.016
synaptic transmissionGO:00072683290.016
gland developmentGO:00487323300.016
positive regulation of cellular amine metabolic processGO:003324050.016
positive regulation of purine nucleotide metabolic processGO:19005441140.016
cation transportGO:00068123990.016
receptor mediated endocytosisGO:0006898510.015
protein localization to organelleGO:00333651850.015
intracellular protein transportGO:00068862040.015
atp metabolic processGO:0046034750.015
cd4 positive alpha beta t cell activationGO:0035710450.015
extracellular structure organizationGO:00430621480.015
phosphatidylglycerol metabolic processGO:004647130.015
ribonucleoside catabolic processGO:00424542060.015
oogenesisGO:0048477560.015
ncrna processingGO:0034470260.015
regulation of nucleotide catabolic processGO:00308111220.015
regulation of feeding behaviorGO:006025930.015
tube closureGO:0060606910.015
small gtpase mediated signal transductionGO:0007264970.014
protein importGO:00170381010.014
regulation of cellular ketone metabolic processGO:0010565660.014
organic hydroxy compound metabolic processGO:19016152030.014
regulation of phosphatidylcholine biosynthetic processGO:200124520.014
action potentialGO:0001508780.014
negative regulation of phosphate metabolic processGO:00459361840.014
regulation of organelle organizationGO:00330432890.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
regulation of gtp catabolic processGO:00331241130.014
maternal determination of anterior posterior axis embryoGO:000835820.013
divalent inorganic cation homeostasisGO:00725071380.013
negative regulation of cellular component organizationGO:00511291940.013
regulation of membrane potentialGO:00423911920.013
energy derivation by oxidation of organic compoundsGO:0015980770.013
negative regulation of alcohol biosynthetic processGO:190293140.013
regulation of lipid metabolic processGO:00192161180.013
mrna metabolic processGO:0016071840.013
t cell proliferationGO:00420981200.013
hematopoietic stem cell differentiationGO:006021880.013
hematopoietic progenitor cell differentiationGO:00022441430.013
positive regulation of protein phosphorylationGO:00019342420.013
small molecule catabolic processGO:0044282710.013
digestive system developmentGO:00551232000.012
trna processingGO:0008033110.012
purine nucleoside biosynthetic processGO:0042451190.012
cytoplasmic transportGO:00164822340.012
organic acid biosynthetic processGO:0016053860.012
cellular chemical homeostasisGO:00550822150.012
guanosine containing compound catabolic processGO:19010691440.012
corticotropin releasing hormone secretionGO:004339620.012
connective tissue developmentGO:00614481790.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
protein targetingGO:00066051430.012
organic acid catabolic processGO:0016054510.012
trna metabolic processGO:0006399110.012
synapse organizationGO:00508081250.012
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.012
negative regulation of cell proliferationGO:00082852960.012
immune effector processGO:00022523210.012
purine ribonucleotide catabolic processGO:00091542080.012
organonitrogen compound catabolic processGO:19015652640.011
purine nucleoside catabolic processGO:00061522050.011
cartilage developmentGO:00512161400.011
leukocyte migrationGO:00509001240.011
mitochondrial dna replicationGO:000626470.011
peptidyl amino acid modificationGO:00181933360.011
glycosyl compound catabolic processGO:19016582060.011
response to transforming growth factor betaGO:0071559880.011
nucleoside catabolic processGO:00091642060.011
metal ion homeostasisGO:00550651890.011
calcium ion transportGO:00068161590.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
posttranscriptional regulation of gene expressionGO:00106081550.011
protein methylationGO:0006479810.011
nucleoside biosynthetic processGO:0009163210.011
response to oxygen levelsGO:0070482620.011
negative regulation of release of cytochrome c from mitochondriaGO:009020160.011
male gamete generationGO:00482322850.011
rna splicing via transesterification reactionsGO:0000375430.011
nucleobase containing compound transportGO:0015931270.010
camera type eye developmentGO:00430102660.010
positive regulation of protein complex assemblyGO:0031334450.010
regulation of mrna processingGO:0050684410.010
regulation of epithelial cell proliferationGO:00506781410.010
neuronal action potentialGO:0019228540.010
blood vessel morphogenesisGO:00485142850.010
t cell differentiationGO:00302171740.010
immune response activating cell surface receptor signaling pathwayGO:0002429720.010
cellular response to transforming growth factor beta stimulusGO:0071560880.010
gtp metabolic processGO:00460391440.010

Parl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.023
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.016
disease of anatomical entityDOID:700.015
sensory system diseaseDOID:005015500.015
nervous system diseaseDOID:86300.015