IMP: Integrative Multi-species Prediction

Mus musculus

56 known processes

Adamts1

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1

(Aliases: ADAMTS,ADAMTS-1,METH-1,C3-C5,ADAM-TS1,METH1)

Ensembl: ENSMUSG00000022893
Entrez: 11504
UniProtKB: P97857

Process Predictions
Disease Predictions

Adamts1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
blood vessel morphogenesis	GO:0048514	285	0.921
urogenital system development	GO:0001655	261	0.773
regulation of protein serine threonine kinase activity	GO:0071900	157	0.722
angiogenesis	GO:0001525	201	0.701
regulation of kinase activity	GO:0043549	249	0.698
renal system development	GO:0072001	225	0.693
wound healing	GO:0042060	157	0.689
cell matrix adhesion	GO:0007160	68	0.674
kidney development	GO:0001822	213	0.655
heart morphogenesis	GO:0003007	178	0.651
cell adhesion	GO:0007155	329	0.649
rhythmic process	GO:0048511	174	0.636
morphogenesis of a branching epithelium	GO:0061138	193	0.596
peptidyl tyrosine modification	GO:0018212	145	0.593
regulation of cellular amino acid metabolic process	GO:0006521	5	0.592
positive regulation of protein phosphorylation	GO:0001934	242	0.588
epithelial tube morphogenesis	GO:0060562	303	0.587
cellular amino acid metabolic process	GO:0006520	103	0.577
regulation of mapk cascade	GO:0043408	248	0.572
cellular amine metabolic process	GO:0044106	44	0.532
chemotaxis	GO:0006935	247	0.493
morphogenesis of a branching structure	GO:0001763	203	0.485
regulation of cytokine production	GO:0001817	266	0.484
axonogenesis	GO:0007409	274	0.480
mapk cascade	GO:0000165	281	0.460
nephron development	GO:0072006	109	0.454
respiratory tube development	GO:0030323	167	0.453
lung development	GO:0030324	164	0.445
positive regulation of protein modification process	GO:0031401	299	0.444
branching morphogenesis of an epithelial tube	GO:0048754	159	0.440
ameboidal type cell migration	GO:0001667	128	0.438
ras protein signal transduction	GO:0007265	77	0.437
endothelial cell migration	GO:0043542	44	0.420
cellular response to lipid	GO:0071396	145	0.419
positive regulation of mapk cascade	GO:0043410	170	0.416
regulation of response to wounding	GO:1903034	189	0.412
amine metabolic process	GO:0009308	45	0.411
extracellular matrix organization	GO:0030198	147	0.401	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.398
single organism cell adhesion	GO:0098602	156	0.377
regulation of cellular response to stress	GO:0080135	159	0.365
cell substrate adhesion	GO:0031589	130	0.365
positive regulation of cellular amine metabolic process	GO:0033240	5	0.361
negative regulation of growth	GO:0045926	99	0.353
regulation of transferase activity	GO:0051338	263	0.351
regulation of protein kinase activity	GO:0045859	232	0.351
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.347
single organismal cell cell adhesion	GO:0016337	131	0.344
placenta development	GO:0001890	140	0.342
ureteric bud development	GO:0001657	94	0.342
peptidyl tyrosine phosphorylation	GO:0018108	143	0.329
cellular ketone metabolic process	GO:0042180	84	0.325
apoptotic signaling pathway	GO:0097190	306	0.313
positive regulation of phospholipase activity	GO:0010518	3	0.312
glial cell differentiation	GO:0010001	131	0.307
rho protein signal transduction	GO:0007266	32	0.303
regulation of inflammatory response	GO:0050727	147	0.300
regulation of protein transport	GO:0051223	163	0.296
regulation of cellular ketone metabolic process	GO:0010565	66	0.294
positive regulation of cytokine production	GO:0001819	174	0.294
extracellular structure organization	GO:0043062	148	0.291	Mouse
striated muscle tissue development	GO:0014706	293	0.282
nuclear transport	GO:0051169	139	0.270
tissue migration	GO:0090130	68	0.269
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.266
response to growth factor	GO:0070848	198	0.264
cytoplasmic transport	GO:0016482	234	0.263	Worm
epithelial cell migration	GO:0010631	63	0.258
epithelium migration	GO:0090132	63	0.255
mesonephric epithelium development	GO:0072163	94	0.251
positive regulation of cell migration	GO:0030335	109	0.251
regulation of protein import into nucleus	GO:0042306	52	0.250
positive regulation of protein kinase activity	GO:0045860	144	0.240
negative regulation of protein metabolic process	GO:0051248	282	0.239
small gtpase mediated signal transduction	GO:0007264	97	0.238
regulation of apoptotic signaling pathway	GO:2001233	197	0.235
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.234
positive regulation of lipid metabolic process	GO:0045834	40	0.234
reactive oxygen species metabolic process	GO:0072593	84	0.232
kidney epithelium development	GO:0072073	121	0.231
cytokine production	GO:0001816	319	0.230
neuron projection guidance	GO:0097485	141	0.230
inflammatory response	GO:0006954	244	0.229
development of primary female sexual characteristics	GO:0046545	73	0.228
cellular response to oxidative stress	GO:0034599	76	0.227
renal tubule morphogenesis	GO:0061333	72	0.227
negative regulation of molecular function	GO:0044092	258	0.226
camera type eye development	GO:0043010	266	0.225
regulation of nucleocytoplasmic transport	GO:0046822	73	0.221
regulation of defense response	GO:0031347	233	0.220
muscle tissue development	GO:0060537	308	0.217
axon guidance	GO:0007411	141	0.215
response to reactive oxygen species	GO:0000302	56	0.214
negative regulation of intracellular signal transduction	GO:1902532	167	0.212
nucleotide metabolic process	GO:0009117	332	0.210
regulation of hydrolase activity	GO:0051336	246	0.209
cell growth	GO:0016049	130	0.208
placenta blood vessel development	GO:0060674	31	0.205
compound eye development	GO:0048749	1	0.204
nephron tubule development	GO:0072080	84	0.204
mesonephric tubule development	GO:0072164	94	0.200
cell chemotaxis	GO:0060326	81	0.199
regulation of ceramide biosynthetic process	GO:2000303	1	0.197
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.195
regulation of angiogenesis	GO:0045765	81	0.192
positive regulation of fibroblast proliferation	GO:0048146	20	0.188
positive regulation of kinase activity	GO:0033674	155	0.181
forebrain cell migration	GO:0021885	58	0.180
defense response to other organism	GO:0098542	197	0.179	Mouse
regulation of cell migration	GO:0030334	219	0.178
digestive tract development	GO:0048565	190	0.176
cellular response to hormone stimulus	GO:0032870	150	0.176
response to organic cyclic compound	GO:0014070	198	0.176
regulation of nucleotide metabolic process	GO:0006140	169	0.174
female gonad development	GO:0008585	71	0.172
positive regulation of cell motility	GO:2000147	116	0.170
peptidyl amino acid modification	GO:0018193	336	0.170
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.170
activation of janus kinase activity	GO:0042976	2	0.168
protein maturation	GO:0051604	176	0.165
regulation of cell adhesion	GO:0030155	154	0.163
developmental maturation	GO:0021700	193	0.163
protein localization to nucleus	GO:0034504	121	0.162
regulation of system process	GO:0044057	200	0.162
response to lipopolysaccharide	GO:0032496	128	0.162
regulation of blood coagulation	GO:0030193	28	0.161
cellular response to growth factor stimulus	GO:0071363	197	0.160
hemostasis	GO:0007599	78	0.160
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.160
telencephalon development	GO:0021537	186	0.156
extrinsic apoptotic signaling pathway	GO:0097191	126	0.156
regulation of peptidase activity	GO:0052547	96	0.155
negative regulation of blood vessel morphogenesis	GO:2000181	25	0.154
regulation of establishment of protein localization	GO:0070201	181	0.153
female sex differentiation	GO:0046660	84	0.152
forebrain development	GO:0030900	302	0.150
regulation of leukocyte differentiation	GO:1902105	159	0.149
regulation of protein localization	GO:0032880	231	0.148
protein import into nucleus	GO:0006606	95	0.148
gland development	GO:0048732	330	0.148
retinal blood vessel morphogenesis	GO:0061304	3	0.148
vascular wound healing	GO:0061042	3	0.146
regulation of vasculature development	GO:1901342	88	0.146
negative regulation of hydrolase activity	GO:0051346	71	0.145
gonad development	GO:0008406	141	0.145
regulation of cell motility	GO:2000145	236	0.144
cerebral cortex cell migration	GO:0021795	44	0.144
negative regulation of vasculature development	GO:1901343	26	0.144
cerebral cortex radially oriented cell migration	GO:0021799	31	0.142
regulation of cell growth	GO:0001558	91	0.142
axon regeneration	GO:0031103	12	0.142
blood vessel endothelial cell migration	GO:0043534	23	0.141
negative regulation of cellular amine metabolic process	GO:0033239	1	0.139
regulation of neuron differentiation	GO:0045664	281	0.138
establishment of protein localization to organelle	GO:0072594	118	0.136
single organism nuclear import	GO:1902593	95	0.136
stem cell development	GO:0048864	219	0.135
nuclear import	GO:0051170	95	0.134
regulation of plasminogen activation	GO:0010755	4	0.133
intussusceptive angiogenesis	GO:0002041	2	0.132
positive regulation of cell development	GO:0010720	237	0.131
regulation of fibroblast proliferation	GO:0048145	34	0.130
ossification	GO:0001503	216	0.130
cardiac chamber morphogenesis	GO:0003206	93	0.130
nucleoside triphosphate catabolic process	GO:0009143	205	0.128
regulation of endopeptidase activity	GO:0052548	89	0.127
regulation of neurotrophin trk receptor signaling pathway	GO:0051386	4	0.126
purine containing compound metabolic process	GO:0072521	311	0.124
lipid biosynthetic process	GO:0008610	179	0.124
protein localization to organelle	GO:0033365	185	0.121
regulation of protein processing	GO:0070613	96	0.121
fibroblast proliferation	GO:0048144	35	0.120
digestive system development	GO:0055123	200	0.117
renal tubule development	GO:0061326	87	0.117
negative regulation of phosphate metabolic process	GO:0045936	184	0.117
superoxide metabolic process	GO:0006801	27	0.116
telencephalon cell migration	GO:0022029	55	0.116
nephron tubule morphogenesis	GO:0072078	68	0.116
nephron epithelium development	GO:0072009	92	0.115
positive regulation of lipid biosynthetic process	GO:0046889	18	0.114
regulation of osteoblast differentiation	GO:0045667	67	0.113
pigment cell differentiation	GO:0050931	27	0.113	Mouse
stem cell differentiation	GO:0048863	268	0.112
negative regulation of angiogenesis	GO:0016525	25	0.111
sphingolipid biosynthetic process	GO:0030148	26	0.111
membrane lipid biosynthetic process	GO:0046467	32	0.109
regulation of lipid metabolic process	GO:0019216	118	0.109
epithelial cell development	GO:0002064	159	0.108
mesenchymal cell development	GO:0014031	93	0.108
labyrinthine layer morphogenesis	GO:0060713	21	0.106
kidney morphogenesis	GO:0060993	83	0.105
positive regulation of sphingolipid biosynthetic process	GO:0090154	1	0.104
negative regulation of cellular protein metabolic process	GO:0032269	247	0.104
response to corticosteroid	GO:0031960	20	0.102
regulation of renal output by angiotensin	GO:0002019	2	0.100
cellular response to peptide	GO:1901653	92	0.100
skeletal system development	GO:0001501	356	0.100
regulation of proteolysis	GO:0030162	164	0.099
regulation of neuron projection development	GO:0010975	169	0.099
ear development	GO:0043583	200	0.098
regulation of map kinase activity	GO:0043405	120	0.097
mesenchyme development	GO:0060485	152	0.097
regulation of heart contraction	GO:0008016	77	0.097
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.097
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.096
regulation of intracellular protein transport	GO:0033157	82	0.096
regulation of epithelial cell migration	GO:0010632	35	0.096
erk1 and erk2 cascade	GO:0070371	77	0.096
leukocyte migration	GO:0050900	124	0.095
cell type specific apoptotic process	GO:0097285	268	0.095
regeneration	GO:0031099	38	0.093
blood circulation	GO:0008015	195	0.093
response to peptide hormone	GO:0043434	127	0.092
cation transport	GO:0006812	399	0.091
mesonephric tubule morphogenesis	GO:0072171	63	0.091
sphingolipid metabolic process	GO:0006665	45	0.091
epithelial cell proliferation	GO:0050673	174	0.090
muscle cell differentiation	GO:0042692	261	0.090
regulation of blood circulation	GO:1903522	93	0.090
negative regulation of phosphorylation	GO:0042326	166	0.089
positive regulation of programmed cell death	GO:0043068	218	0.089
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.089
coagulation	GO:0050817	78	0.088
transmembrane transport	GO:0055085	412	0.088
nephron epithelium morphogenesis	GO:0072088	68	0.088
negative regulation of cell proliferation	GO:0008285	296	0.088
embryonic placenta development	GO:0001892	98	0.087
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.087
organ growth	GO:0035265	117	0.087
protein import	GO:0017038	101	0.086
response to transforming growth factor beta	GO:0071559	88	0.086
purine nucleotide metabolic process	GO:0006163	302	0.086
cellular response to organic cyclic compound	GO:0071407	87	0.086
embryonic organ morphogenesis	GO:0048562	276	0.085
regulation of protein targeting	GO:1903533	61	0.085
circulatory system process	GO:0003013	197	0.085
phagocytosis	GO:0006909	66	0.084
negative regulation of neurotrophin trk receptor signaling pathway	GO:0051387	2	0.084
regulation of morphogenesis of a branching structure	GO:0060688	53	0.083
mesonephros development	GO:0001823	97	0.083
negative regulation of protein maturation	GO:1903318	79	0.083
intracellular protein transport	GO:0006886	204	0.082
organonitrogen compound biosynthetic process	GO:1901566	192	0.082
positive regulation of neuron differentiation	GO:0045666	141	0.081
renal system process	GO:0003014	48	0.081
regulation of organelle organization	GO:0033043	289	0.081
synaptic transmission	GO:0007268	329	0.081
response to radiation	GO:0009314	165	0.081
regulation of transcription factor import into nucleus	GO:0042990	24	0.081
negative regulation of fibrinolysis	GO:0051918	1	0.081
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.080
organic hydroxy compound metabolic process	GO:1901615	203	0.080
regulation of activation of jak2 kinase activity	GO:0010534	1	0.080
defense response to bacterium	GO:0042742	119	0.080	Mouse
positive regulation of leukocyte differentiation	GO:1902107	86	0.080
respiratory system development	GO:0060541	190	0.080
negative regulation of proteolysis	GO:0045861	74	0.080
regulation of sphingolipid biosynthetic process	GO:0090153	1	0.079
nucleobase containing small molecule metabolic process	GO:0055086	352	0.079
immune effector process	GO:0002252	321	0.079
organophosphate catabolic process	GO:0046434	232	0.078
leukocyte differentiation	GO:0002521	342	0.078
osteoclast differentiation	GO:0030316	62	0.077
ureteric bud morphogenesis	GO:0060675	62	0.077
neuroepithelial cell differentiation	GO:0060563	37	0.077	Mouse
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.077
negative regulation of response to wounding	GO:1903035	77	0.077
positive regulation of protein transport	GO:0051222	93	0.076
heart contraction	GO:0060047	93	0.076
nerve development	GO:0021675	67	0.074
positive regulation of apoptotic process	GO:0043065	217	0.074
smoothened signaling pathway	GO:0007224	105	0.074
positive regulation of cell death	GO:0010942	224	0.074
regulation of cellular catabolic process	GO:0031329	242	0.073
chromatin organization	GO:0006325	206	0.073
response to metal ion	GO:0010038	47	0.073
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.072
negative regulation of endothelial cell migration	GO:0010596	4	0.072
glycerolipid metabolic process	GO:0046486	122	0.071
meiotic cell cycle	GO:0051321	122	0.071
peripheral nervous system axon regeneration	GO:0014012	2	0.070
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.070
cerebral cortex development	GO:0021987	86	0.069
negative regulation of neuron death	GO:1901215	98	0.069
negative regulation of protein processing	GO:0010955	79	0.069
developmental cell growth	GO:0048588	84	0.067
positive regulation of neuron projection development	GO:0010976	79	0.067
neuron migration	GO:0001764	122	0.067
organonitrogen compound catabolic process	GO:1901565	264	0.066
skeletal muscle organ development	GO:0060538	163	0.066
skeletal system morphogenesis	GO:0048705	203	0.065
development of primary sexual characteristics	GO:0045137	143	0.065
macromolecule deacylation	GO:0098732	37	0.065
regulation of protein localization to nucleus	GO:1900180	60	0.065
endothelial cell differentiation	GO:0045446	41	0.064
nucleoside phosphate metabolic process	GO:0006753	338	0.064
integrin mediated signaling pathway	GO:0007229	27	0.063
fat cell differentiation	GO:0045444	160	0.063
regulation of purine nucleotide metabolic process	GO:1900542	169	0.062
regulation of cell cycle	GO:0051726	281	0.062
regulation of bmp signaling pathway	GO:0030510	60	0.061
glial cell development	GO:0021782	54	0.061
cellular response to organonitrogen compound	GO:0071417	145	0.061
regulation of protein deacetylation	GO:0090311	17	0.061
regulation of organ morphogenesis	GO:2000027	144	0.061
regulation of cytoplasmic transport	GO:1903649	112	0.061
sensory system development	GO:0048880	3	0.061
vitellogenesis	GO:0007296	2	0.060
positive regulation of epithelial cell migration	GO:0010634	19	0.059
response to molecule of bacterial origin	GO:0002237	143	0.059
response to inorganic substance	GO:0010035	96	0.059
cartilage development	GO:0051216	140	0.059
regulation of hemostasis	GO:1900046	28	0.059
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.058
negative regulation of intracellular transport	GO:0032387	38	0.058
positive regulation of lipase activity	GO:0060193	6	0.058
protein processing	GO:0016485	163	0.058
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	4	0.058
positive regulation of bmp signaling pathway	GO:0030513	23	0.058
regulation of lipid biosynthetic process	GO:0046890	54	0.058
heart process	GO:0003015	94	0.057
cellular chemical homeostasis	GO:0055082	215	0.057
negative regulation of cell adhesion	GO:0007162	45	0.057
engulfment of apoptotic cell	GO:0043652	3	0.056
cardiac muscle tissue development	GO:0048738	130	0.056
nucleocytoplasmic transport	GO:0006913	139	0.056
negative regulation of neuron projection regeneration	GO:0070571	3	0.056
negative regulation of nervous system development	GO:0051961	156	0.056
cellular lipid metabolic process	GO:0044255	323	0.056
dephosphorylation	GO:0016311	129	0.056
protein secretion	GO:0009306	111	0.056
response to oxidative stress	GO:0006979	123	0.055
response to steroid hormone	GO:0048545	56	0.055
glomerulus development	GO:0032835	40	0.055
reactive nitrogen species metabolic process	GO:2001057	0	0.054
neuron projection regeneration	GO:0031102	14	0.054
negative regulation of peptidase activity	GO:0010466	46	0.054
renin angiotensin regulation of aldosterone production	GO:0002018	3	0.054
regulation of tube size	GO:0035150	57	0.054
chorio allantoic fusion	GO:0060710	8	0.053
innervation	GO:0060384	22	0.053
positive regulation of osteoclast differentiation	GO:0045672	15	0.053
vasoconstriction	GO:0042310	27	0.052
myeloid cell differentiation	GO:0030099	233	0.052
pallium development	GO:0021543	120	0.052
response to drug	GO:0042493	75	0.052
negative regulation of smooth muscle cell migration	GO:0014912	2	0.052
regulation of removal of superoxide radicals	GO:2000121	4	0.051
blood coagulation	GO:0007596	76	0.051
cellular response to cytokine stimulus	GO:0071345	189	0.051
oviduct development	GO:0060066	3	0.050
macromolecule catabolic process	GO:0009057	281	0.050
digestive tract morphogenesis	GO:0048546	147	0.050
regulation of cell substrate adhesion	GO:0010810	73	0.050
multicellular organism growth	GO:0035264	161	0.050
negative regulation of cellular response to growth factor stimulus	GO:0090288	46	0.050
guanosine containing compound metabolic process	GO:1901068	144	0.050
regulation of ossification	GO:0030278	112	0.049
gliogenesis	GO:0042063	141	0.049
glycerophospholipid metabolic process	GO:0006650	71	0.049
regulation of protein maturation	GO:1903317	96	0.049
regulation of lipase activity	GO:0060191	15	0.049
positive regulation of renal sodium excretion	GO:0035815	2	0.049
cellular response to inorganic substance	GO:0071241	37	0.049
organic cyclic compound catabolic process	GO:1901361	295	0.048
regionalization	GO:0003002	337	0.048
renal sodium excretion	GO:0035812	3	0.048
purine ribonucleotide metabolic process	GO:0009150	290	0.048
peripheral nervous system development	GO:0007422	53	0.048
skin development	GO:0043588	220	0.048
epiboly	GO:0090504	8	0.048
platelet aggregation	GO:0070527	20	0.048
negative regulation of protein modification process	GO:0031400	163	0.048
negative regulation of t helper 2 cell differentiation	GO:0045629	4	0.047
cellular homeostasis	GO:0019725	240	0.047
cellular response to extracellular stimulus	GO:0031668	81	0.047
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.047
metanephros development	GO:0001656	79	0.047
developmental growth involved in morphogenesis	GO:0060560	138	0.047
steroid metabolic process	GO:0008202	119	0.047
reactive oxygen species biosynthetic process	GO:1903409	8	0.047
triglyceride metabolic process	GO:0006641	51	0.047
lipid transport	GO:0006869	98	0.047
negative regulation of cell development	GO:0010721	169	0.047
negative regulation of cell growth	GO:0030308	44	0.046
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.046
regulation of intracellular transport	GO:0032386	159	0.046
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.046
multicellular organismal signaling	GO:0035637	91	0.046
positive regulation of nervous system development	GO:0051962	221	0.045
regulation of neuron death	GO:1901214	134	0.045
cardiac chamber development	GO:0003205	108	0.045
positive regulation of chemotaxis	GO:0050921	38	0.044
response to oxygen levels	GO:0070482	62	0.044
gtp metabolic process	GO:0046039	144	0.044
apoptotic cell clearance	GO:0043277	17	0.044
nephron morphogenesis	GO:0072028	69	0.044
endocytosis	GO:0006897	168	0.044
positive regulation of glial cell proliferation	GO:0060252	4	0.044
positive regulation of blood pressure	GO:0045777	21	0.044
heart trabecula formation	GO:0060347	14	0.043
regulation of renal sodium excretion	GO:0035813	3	0.043
myosin filament organization	GO:0031033	3	0.043
ribonucleotide metabolic process	GO:0009259	291	0.043
notochord development	GO:0030903	20	0.043
mesoderm morphogenesis	GO:0048332	64	0.043
negative regulation of neuron differentiation	GO:0045665	101	0.043
response to decreased oxygen levels	GO:0036293	59	0.043
chondrocyte differentiation	GO:0002062	72	0.043
transforming growth factor beta2 production	GO:0032906	2	0.042
anatomical structure maturation	GO:0071695	49	0.042
regulation of cell activation	GO:0050865	289	0.042
response to organonitrogen compound	GO:0010243	246	0.042
heart trabecula morphogenesis	GO:0061384	26	0.041
ovulation	GO:0030728	15	0.041
regulation of myeloid leukocyte differentiation	GO:0002761	58	0.041
positive regulation of response to wounding	GO:1903036	66	0.041
response to low density lipoprotein particle	GO:0055098	2	0.041
regulation of endothelial cell migration	GO:0010594	22	0.041
positive regulation of osteoblast differentiation	GO:0045669	34	0.041
mitotic cell cycle process	GO:1903047	159	0.041
t cell activation	GO:0042110	289	0.041
response to estrogen	GO:0043627	24	0.041
ribonucleoside catabolic process	GO:0042454	206	0.040
wound healing spreading of cells	GO:0044319	8	0.040
positive regulation of cell activation	GO:0050867	158	0.040
organic hydroxy compound transport	GO:0015850	93	0.040
purine nucleoside catabolic process	GO:0006152	205	0.040
regulation of ras protein signal transduction	GO:0046578	114	0.040
g protein coupled receptor signaling pathway	GO:0007186	243	0.039
transmission of nerve impulse	GO:0019226	76	0.039
epithelial to mesenchymal transition	GO:0001837	47	0.039
negative regulation of wnt signaling pathway	GO:0030178	73	0.039
muscle contraction	GO:0006936	101	0.039
cell adhesion mediated by integrin	GO:0033627	18	0.039
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	GO:1902238	1	0.038
cellular response to steroid hormone stimulus	GO:0071383	33	0.038
acylglycerol metabolic process	GO:0006639	55	0.038
response to oxygen radical	GO:0000305	16	0.038
cellular response to peptide hormone stimulus	GO:0071375	92	0.038
mitotic cell cycle	GO:0000278	195	0.038
embryonic placenta morphogenesis	GO:0060669	25	0.038
striated muscle cell development	GO:0055002	125	0.038
labyrinthine layer development	GO:0060711	49	0.038
substrate adhesion dependent cell spreading	GO:0034446	30	0.038
regulation of fibrinolysis	GO:0051917	1	0.038
ceramide biosynthetic process	GO:0046513	20	0.038
mesenchymal cell differentiation	GO:0048762	107	0.037
regulation of body fluid levels	GO:0050878	162	0.037
cytokine production involved in immune response	GO:0002367	34	0.037
regulation of epithelial cell proliferation	GO:0050678	141	0.037
negative regulation of intracellular protein transport	GO:0090317	27	0.037
chondroblast differentiation	GO:0060591	2	0.037
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	43	0.037
wnt signaling pathway	GO:0016055	188	0.036
negative regulation of endopeptidase activity	GO:0010951	44	0.036
response to nutrient levels	GO:0031667	109	0.036
production of molecular mediator of immune response	GO:0002440	103	0.036
regulation of phosphatidylcholine catabolic process	GO:0010899	2	0.035
positive regulation of myeloid leukocyte differentiation	GO:0002763	26	0.035
positive regulation of endothelial cell migration	GO:0010595	12	0.035
regulation of nucleotide catabolic process	GO:0030811	122	0.035
cardiac muscle cell development	GO:0055013	39	0.035
regulation of anatomical structure size	GO:0090066	178	0.035
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.035	Mouse
regulation of jak stat cascade	GO:0046425	34	0.035
regulation of cellular component biogenesis	GO:0044087	181	0.035
i kappab kinase nf kappab signaling	GO:0007249	85	0.035
positive regulation of cartilage development	GO:0061036	18	0.035
negative regulation of neuron apoptotic process	GO:0043524	92	0.035
cardiac cell development	GO:0055006	41	0.035
regulation of activation of janus kinase activity	GO:0010533	1	0.035
insulin receptor signaling pathway	GO:0008286	49	0.035
phospholipid metabolic process	GO:0006644	87	0.035
multi multicellular organism process	GO:0044706	109	0.034
second messenger mediated signaling	GO:0019932	73	0.034
cellular response to molecule of bacterial origin	GO:0071219	83	0.034
removal of superoxide radicals	GO:0019430	12	0.034
chondrocyte proliferation	GO:0035988	6	0.034
peptidyl proline hydroxylation	GO:0019511	3	0.034
positive regulation of transferase activity	GO:0051347	167	0.034
gtp catabolic process	GO:0006184	143	0.034
vascular process in circulatory system	GO:0003018	62	0.034
positive regulation of hydrolase activity	GO:0051345	148	0.034
regulation of blood vessel size	GO:0050880	56	0.034
stress activated protein kinase signaling cascade	GO:0031098	81	0.034

Adamts1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.327
cardiovascular system disease	DOID:1287	0.327
nervous system disease	DOID:863	0.289
heart disease	DOID:114	0.079
muscular disease	DOID:0080000	0.074
musculoskeletal system disease	DOID:17	0.074
hypertension	DOID:10763	0.072
artery disease	DOID:0050828	0.072
vascular disease	DOID:178	0.072
essential hypertension	DOID:10825	0.072
disease of metabolism	DOID:0014667	0.068
central nervous system disease	DOID:331	0.043
sensory system disease	DOID:0050155	0.037

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