Mus musculus

44 known processes

Adamts2

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2

(Aliases: mKIAA4060,A430089F14,ADAMTS-3,hPCPNI,4732482M10,KIAA4060,PCINP,ADAM-TS2)

Adamts2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
extracellular structure organizationGO:00430621480.933
extracellular matrix organizationGO:00301981470.911
collagen fibril organizationGO:0030199320.502
urogenital system developmentGO:00016552610.485
Mouse
response to growth factorGO:00708481980.458
regulation of cell adhesionGO:00301551540.396
skeletal system developmentGO:00015013560.226
cellular response to growth factor stimulusGO:00713631970.223
endochondral bone morphogenesisGO:0060350500.215
blood vessel morphogenesisGO:00485142850.215
bone developmentGO:00603481200.204
cellular response to amino acid stimulusGO:0071230290.194
heart morphogenesisGO:00030071780.176
cell adhesionGO:00071553290.174
cellular response to organonitrogen compoundGO:00714171450.147
trabecula formationGO:0060343240.142
embryonic skeletal system morphogenesisGO:0048704910.142
protein heterooligomerizationGO:0051291140.130
sensory organ morphogenesisGO:00905962420.125
small gtpase mediated signal transductionGO:0007264970.123
cell substrate adhesionGO:00315891300.121
protein heterotrimerizationGO:007020880.120
physiological cardiac muscle hypertrophyGO:000330130.120
respiratory system developmentGO:00605411900.120
ossificationGO:00015032160.119
renal system developmentGO:00720012250.115
Mouse
regulation of cytokine productionGO:00018172660.111
regulation of cell motilityGO:20001452360.108
regulation of angiogenesisGO:0045765810.099
oxidation reduction processGO:00551143420.097
extrinsic apoptotic signaling pathwayGO:00971911260.096
protein trimerizationGO:0070206130.094
chondrocyte differentiationGO:0002062720.092
palate developmentGO:0060021760.090
response to amino acidGO:0043200370.090
transforming growth factor beta receptor signaling pathwayGO:0007179710.088
cardiac chamber developmentGO:00032051080.087
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.087
connective tissue developmentGO:00614481790.086
cell matrix adhesionGO:0007160680.085
negative regulation of cellular response to growth factor stimulusGO:0090288460.079
appendage morphogenesisGO:00351071490.079
cellular response to transforming growth factor beta stimulusGO:0071560880.079
digestive system developmentGO:00551232000.077
lung developmentGO:00303241640.077
protein maturationGO:00516041760.077
protein oligomerizationGO:0051259670.076
negative regulation of cell migrationGO:0030336590.076
positive regulation of nervous system developmentGO:00519622210.075
embryonic skeletal system developmentGO:00487061200.075
proteoglycan metabolic processGO:0006029380.074
skin developmentGO:00435882200.073
apoptotic signaling pathwayGO:00971903060.070
kidney developmentGO:00018222130.067
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.067
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.066
nephron developmentGO:00720061090.066
Mouse
response to organonitrogen compoundGO:00102432460.064
trabecula morphogenesisGO:0061383400.063
respiratory tube developmentGO:00303231670.063
regulation of cell migrationGO:00303342190.062
epithelial cell proliferationGO:00506731740.061
regulation of apoptotic signaling pathwayGO:20012331970.060
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.058
forebrain developmentGO:00309003020.057
cell recognitionGO:0008037830.057
fat cell differentiationGO:00454441600.055
spermatogenesisGO:00072832840.054
negative regulation of cell adhesionGO:0007162450.053
defense response to bacteriumGO:00427421190.053
negative regulation of apoptotic signaling pathwayGO:20012341040.052
hexose metabolic processGO:0019318980.052
cartilage development involved in endochondral bone morphogenesisGO:0060351240.051
limb developmentGO:00601731660.051
camera type eye developmentGO:00430102660.051
cardiac chamber morphogenesisGO:0003206930.051
ureteric bud developmentGO:0001657940.051
Mouse
ovulationGO:0030728150.050
appendage developmentGO:00487361660.048
regulation of cellular ketone metabolic processGO:0010565660.048
anatomical structure homeostasisGO:00602491450.047
branching morphogenesis of an epithelial tubeGO:00487541590.047
Mouse
positive regulation of cell substrate adhesionGO:0010811470.047
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.047
kidney epithelium developmentGO:00720731210.047
Mouse
digestive tract developmentGO:00485651900.046
cellular response to bmp stimulusGO:0071773140.046
positive regulation of cell adhesionGO:0045785800.045
positive regulation of cellular amine metabolic processGO:003324050.045
ear developmentGO:00435832000.044
positive regulation of cytokine productionGO:00018191740.044
regulation of fat cell differentiationGO:0045598810.044
regulation of response to woundingGO:19030341890.043
cellular response to acid chemicalGO:0071229680.043
response to bmpGO:0071772140.043
limb morphogenesisGO:00351081490.043
glycoprotein metabolic processGO:00091001160.043
cell growth involved in cardiac muscle cell developmentGO:006104930.043
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.043
mesenchyme developmentGO:00604851520.042
carbohydrate metabolic processGO:00059752300.042
muscle tissue developmentGO:00605373080.041
male gamete generationGO:00482322850.041
elastic fiber assemblyGO:004825140.041
recognition of apoptotic cellGO:004365430.040
signal transduction in absence of ligandGO:0038034550.040
mesonephros developmentGO:0001823970.040
Mouse
regulation of system processGO:00440572000.039
developmental maturationGO:00217001930.039
telencephalon developmentGO:00215371860.039
adiponectin secretionGO:007016220.039
angiogenesisGO:00015252010.038
negative regulation of cell growth involved in cardiac muscle cell developmentGO:006105220.038
lateral line system developmentGO:004892510.037
organ growthGO:00352651170.037
positive regulation of cellular amino acid metabolic processGO:004576430.037
head morphogenesisGO:0060323340.037
physiological muscle hypertrophyGO:000329830.037
positive regulation of adiponectin secretionGO:007016510.036
pallium developmentGO:00215431200.036
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.036
odontogenesisGO:0042476780.035
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.035
carbohydrate homeostasisGO:00335001280.035
negative regulation of nervous system developmentGO:00519611560.035
cytokine productionGO:00018163190.034
renal tubule morphogenesisGO:0061333720.034
Mouse
fibril organizationGO:009743520.033
cerebral cortex developmentGO:0021987860.033
regulation of cellular amine metabolic processGO:0033238200.033
negative regulation of epithelial cell proliferationGO:0050680640.032
cellular amino acid metabolic processGO:00065201030.032
central nervous system vasculogenesisGO:002200930.031
striated muscle tissue developmentGO:00147062930.030
heart trabecula formationGO:0060347140.030
cardiac muscle tissue developmentGO:00487381300.029
skeletal system morphogenesisGO:00487052030.029
bone trabecula formationGO:006034690.028
bone trabecula morphogenesisGO:0061430120.028
cellular lipid metabolic processGO:00442553230.028
embryonic organ morphogenesisGO:00485622760.028
regulation of vasculature developmentGO:1901342880.028
prostate gland morphogenesisGO:0060512320.028
kidney morphogenesisGO:0060993830.027
Mouse
endoderm developmentGO:0007492450.027
muscle tissue morphogenesisGO:0060415530.027
negative regulation of cell developmentGO:00107211690.027
lateral inhibitionGO:004633110.027
rho protein signal transductionGO:0007266320.027
monocarboxylic acid metabolic processGO:00327871910.026
negative regulation of neuron migrationGO:200122360.026
sensory system developmentGO:004888030.026
ear morphogenesisGO:00424711180.026
hexose biosynthetic processGO:0019319390.025
bone morphogenesisGO:0060349780.025
cardiac ventricle morphogenesisGO:0003208500.025
regulation of neuron migrationGO:2001222220.025
uterus morphogenesisGO:006103820.025
response to acid chemicalGO:00011011110.025
regulation of organ growthGO:0046620610.025
stem cell differentiationGO:00488632680.025
regulation of adiponectin secretionGO:007016320.025
negative regulation of neuron differentiationGO:00456651010.025
axonogenesisGO:00074092740.024
development of primary female sexual characteristicsGO:0046545730.024
negative regulation of cell motilityGO:2000146610.024
formation of primary germ layerGO:0001704770.024
tissue migrationGO:0090130680.024
regulation of hormone levelsGO:00108172110.024
notochord developmentGO:0030903200.024
regulation of carbohydrate metabolic processGO:0006109750.024
peptide transportGO:00158331330.023
endochondral bone growthGO:0003416190.023
regulation of ras protein signal transductionGO:00465781140.023
cellular carbohydrate metabolic processGO:00442621190.023
neuron projection guidanceGO:00974851410.023
metanephros developmentGO:0001656790.023
glucose metabolic processGO:0006006920.023
sensory perceptionGO:00076002450.023
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.023
single organism cell adhesionGO:00986021560.022
positive regulation of fatty acid oxidationGO:004632140.022
inner ear morphogenesisGO:00424721010.022
interleukin 8 secretionGO:007260630.022
ras protein signal transductionGO:0007265770.022
regulation of chondrocyte differentiationGO:0032330330.022
cartilage developmentGO:00512161400.022
negative regulation of phospholipase activityGO:001051940.022
pigmentationGO:0043473710.022
nitrogen compound transportGO:00717052710.021
response to oxidative stressGO:00069791230.021
chondrocyte developmentGO:0002063240.021
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.021
amine metabolic processGO:0009308450.021
cell adhesion mediated by integrinGO:0033627180.021
regulation of glucose metabolic processGO:0010906600.021
positive regulation of protein modification processGO:00314012990.021
female gonad developmentGO:0008585710.021
regulation of cardiac muscle tissue growthGO:0055021260.021
female sex differentiationGO:0046660840.021
carbohydrate biosynthetic processGO:0016051740.021
cellular amine metabolic processGO:0044106440.021
aorta smooth muscle tissue morphogenesisGO:006041420.021
regulation of cellular amino acid metabolic processGO:000652150.020
ameboidal type cell migrationGO:00016671280.020
myeloid leukocyte migrationGO:0097529570.020
positive regulation of neuron projection regenerationGO:007057220.020
chemotaxisGO:00069352470.019
extracellular matrix assemblyGO:0085029120.019
replacement ossificationGO:0036075260.019
multicellular organism growthGO:00352641610.019
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.019
monosaccharide metabolic processGO:00059961060.019
nephron tubule developmentGO:0072080840.019
Mouse
embryonic limb morphogenesisGO:00303261260.019
dorsal ventral axon guidanceGO:003356330.019
gliogenesisGO:00420631410.019
regulation of rho protein signal transductionGO:0035023710.018
face developmentGO:0060324380.018
interleukin 8 productionGO:003263740.018
response to reactive oxygen speciesGO:0000302560.018
regulation of endothelial cell migrationGO:0010594220.018
negative regulation of intracellular signal transductionGO:19025321670.018
cellular response to external stimulusGO:0071496880.018
regulation of proteolysisGO:00301621640.018
cellular response to oxidative stressGO:0034599760.018
negative regulation of cell proliferationGO:00082852960.018
regulation of secretionGO:00510462740.018
cellular macromolecule catabolic processGO:00442652060.018
cellular response to cytokine stimulusGO:00713451890.018
neuroepithelial cell differentiationGO:0060563370.018
glucose homeostasisGO:00425931280.017
female gamete generationGO:0007292740.017
bmp signaling pathwayGO:0030509930.017
response to monosaccharideGO:0034284670.017
regionalizationGO:00030023370.017
ventricular cardiac muscle tissue morphogenesisGO:0055010320.017
smoothened signaling pathwayGO:00072241050.017
mitotic cell cycleGO:00002781950.017
cardiac ventricle developmentGO:0003231830.017
mesenchymal cell differentiationGO:00487621070.017
positive regulation of developmental pigmentationGO:004808760.017
growth plate cartilage developmentGO:0003417140.017
negative regulation of macrophage chemotaxisGO:001076010.017
negative regulation of cellular component organizationGO:00511291940.017
gonad developmentGO:00084061410.017
regulation of mapk cascadeGO:00434082480.016
heart trabecula morphogenesisGO:0061384260.016
stem cell developmentGO:00488642190.016
regulation of cellular carbohydrate metabolic processGO:0010675750.016
antimicrobial peptide secretionGO:000277610.016
cellular glucan metabolic processGO:0006073320.016
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080210.016
morphogenesis of an endotheliumGO:000315920.016
negative regulation of proteolysisGO:0045861740.016
positive regulation of melanocyte differentiationGO:004563650.016
sensory perception of mechanical stimulusGO:00509541070.016
positive regulation of apoptotic processGO:00430652170.015
positive regulation of cell projection organizationGO:0031346950.015
anatomical structure maturationGO:0071695490.015
activation of immune responseGO:00022531380.015
positive regulation of pigment cell differentiationGO:005094250.015
prostate gland epithelium morphogenesisGO:0060740310.015
cellular response to inorganic substanceGO:0071241370.015
regulation of protein maturationGO:1903317960.015
cardiac muscle tissue growthGO:0055017370.015
positive regulation of cell developmentGO:00107202370.015
midgut developmentGO:000749440.015
cardiac muscle hypertrophyGO:0003300230.015
nucleobase containing small molecule metabolic processGO:00550863520.015
negative regulation of blood vessel morphogenesisGO:2000181250.015
mucopolysaccharide metabolic processGO:1903510250.015
ventricular cardiac muscle tissue developmentGO:0003229380.015
regulation of organelle organizationGO:00330432890.015
regulation of protein secretionGO:0050708820.015
regulation of chemotaxisGO:0050920530.015
neuron migrationGO:00017641220.015
ovulation from ovarian follicleGO:000154290.015
regulation of bmp signaling pathwayGO:0030510600.015
negative regulation of immune system processGO:00026832090.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.015
positive regulation of cell migrationGO:00303351090.015
response to transforming growth factor betaGO:0071559880.014
positive regulation of cell deathGO:00109422240.014
transmembrane transportGO:00550854120.014
regulation of peptidase activityGO:0052547960.014
regulation of developmental pigmentationGO:0048070140.014
cellular response to nitric oxideGO:007173240.014
regulation of cell migration involved in sprouting angiogenesisGO:009004940.014
segmentationGO:0035282930.014
leukocyte chemotaxisGO:0030595690.014
positive regulation of apoptotic signaling pathwayGO:2001235950.014
melanocyte differentiationGO:0030318250.014
glucose transportGO:0015758560.014
heart growthGO:0060419450.014
positive regulation of hormone secretionGO:0046887380.014
multicellular organismal homeostasisGO:00488711640.014
hormone secretionGO:00468791280.014
regulation of testosterone biosynthetic processGO:200022420.014
ovulation cycleGO:0042698590.014
neuromuscular processGO:0050905990.014
nephron tubule morphogenesisGO:0072078680.014
Mouse
hematopoietic progenitor cell differentiationGO:00022441430.013
defense response to other organismGO:00985421970.013
cellular ketone metabolic processGO:0042180840.013
positive regulation vascular endothelial growth factor productionGO:0010575100.013
response to inorganic substanceGO:0010035960.013
regulation of epithelial cell proliferationGO:00506781410.013
glial cell migrationGO:000834770.013
sperm egg recognitionGO:0035036370.013
development of primary sexual characteristicsGO:00451371430.013
innate immune responseGO:00450871570.013
negative regulation of growthGO:0045926990.013
reactive oxygen species biosynthetic processGO:190340980.013
protein hydroxylationGO:001812640.013
glucan metabolic processGO:0044042320.013
regulation of defense responseGO:00313472330.013
regulation of epithelial cell migrationGO:0010632350.013
synapse organizationGO:00508081250.013
sulfur compound metabolic processGO:00067901000.013
single fertilizationGO:0007338820.013
endothelial cell migrationGO:0043542440.013
odontogenesis of dentin containing toothGO:0042475660.013
mesenchymal cell developmentGO:0014031930.013
renal tubule developmentGO:0061326870.012
Mouse
regulation of carbohydrate biosynthetic processGO:0043255400.012
cell chemotaxisGO:0060326810.012
metanephric loop of henle developmentGO:007223640.012
insulin processingGO:003007020.012
transmission of nerve impulseGO:0019226760.012
generation of precursor metabolites and energyGO:00060911030.012
gland developmentGO:00487323300.012
single organismal cell cell adhesionGO:00163371310.012
humoral immune responseGO:0006959570.012
epithelial tube morphogenesisGO:00605623030.012
Mouse
endomembrane system organizationGO:00102561470.012
regulation of cell projection organizationGO:00313442060.012
developmental pigmentationGO:0048066400.012
regulation of cell substrate adhesionGO:0010810730.012
germ cell developmentGO:00072811850.012
immune effector processGO:00022523210.012
compound eye developmentGO:004874910.012
retina development in camera type eyeGO:00600411190.012
regulation of smoothened signaling pathwayGO:0008589580.012
extracellular fibril organizationGO:004320620.012
regulation of protein processingGO:0070613960.012
negative regulation of protein maturationGO:1903318790.012
mesonephric duct morphogenesisGO:007218040.012
oviduct developmentGO:006006630.012
mesonephric epithelium developmentGO:0072163940.012
Mouse
cellular modified amino acid metabolic processGO:0006575630.011
negative regulation of fat cell differentiationGO:0045599360.011
antimicrobial peptide biosynthetic processGO:000277720.011
negative regulation of angiogenesisGO:0016525250.011
rhythmic processGO:00485111740.011
protein processingGO:00164851630.011
gastrulationGO:00073691160.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.011
fatty acid metabolic processGO:00066311210.011
face morphogenesisGO:0060325290.011
epithelial cell developmentGO:00020641590.011
neuromuscular process controlling balanceGO:0050885590.011
phagosome maturationGO:009038240.011
regulation of secretion by cellGO:19035302490.011
negative regulation of bmp signaling pathwayGO:0030514350.011
regulation of cardiac muscle hypertrophyGO:0010611130.011
tissue remodelingGO:00487711020.011
negative regulation of lipoprotein lipase activityGO:005100510.011
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.011
regulation of anatomical structure sizeGO:00900661780.011
fertilizationGO:00095661270.011
tendon developmentGO:003598960.011
lipid modificationGO:0030258650.011
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.011
epidermis morphogenesisGO:0048730330.011
cellular response to mechanical stimulusGO:007126070.011
sprouting angiogenesisGO:0002040260.011
positive regulation of bmp signaling pathwayGO:0030513230.011
positive regulation of glucose importGO:0046326140.011
positive regulation of secretion by cellGO:19035321140.011
adult behaviorGO:00305341350.011
positive regulation of anagenGO:005188510.011
ubiquitin dependent smad protein catabolic processGO:003057920.011
positive regulation of protein kinase activityGO:00458601440.011
positive regulation of proteolysisGO:0045862850.010
cellular polysaccharide metabolic processGO:0044264380.010
positive regulation of behaviorGO:0048520400.010
positive regulation of glucose transportGO:0010828160.010
cardiac cell developmentGO:0055006410.010
response to endoplasmic reticulum stressGO:0034976530.010
cellular response to hormone stimulusGO:00328701500.010
inflammatory responseGO:00069542440.010
positive regulation of transferase activityGO:00513471670.010
positive regulation of cellular carbohydrate metabolic processGO:0010676290.010
glucose importGO:0046323320.010
negative regulation of neuron projection regenerationGO:007057130.010
peptide secretionGO:00027901140.010
monosaccharide transportGO:0015749580.010
aorta developmentGO:0035904230.010
aorta morphogenesisGO:0035909220.010
cellular response to abiotic stimulusGO:0071214560.010
regulation of interleukin 8 productionGO:003267730.010
protein catabolic processGO:00301632210.010
mesonephric tubule developmentGO:0072164940.010
Mouse

Adamts2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.583
nervous system diseaseDOID:86300.583
sensory system diseaseDOID:005015500.583
musculoskeletal system diseaseDOID:1700.436
muscular diseaseDOID:008000000.263
muscle tissue diseaseDOID:6600.238
myopathyDOID:42300.238
eye and adnexa diseaseDOID:149200.120
eye diseaseDOID:561400.120
connective tissue diseaseDOID:6500.098
muscular dystrophyDOID:988400.086
retinal diseaseDOID:567900.072
congenital muscular dystrophyDOID:005055700.052
bone development diseaseDOID:008000600.049
bone diseaseDOID:008000100.049
osteochondrodysplasiaDOID:225600.023
retinal degenerationDOID:846600.019
osteogenesis imperfectaDOID:1234700.010