Mus musculus

0 known processes

Hecw2

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

(Aliases: Gm971,A730039N16Rik,Nedl2,mKIAA1301,D030049F17Rik)

Hecw2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide metabolic processGO:00091173320.096
purine nucleotide metabolic processGO:00061633020.094
ribose phosphate metabolic processGO:00196932910.091
gtp metabolic processGO:00460391440.086
nucleobase containing small molecule metabolic processGO:00550863520.083
nucleoside phosphate catabolic processGO:19012922220.082
purine nucleoside catabolic processGO:00061522050.081
organonitrogen compound catabolic processGO:19015652640.080
purine ribonucleotide metabolic processGO:00091502900.080
purine nucleotide catabolic processGO:00061952110.080
nucleoside catabolic processGO:00091642060.079
heterocycle catabolic processGO:00467002800.077
small gtpase mediated signal transductionGO:0007264970.074
rho protein signal transductionGO:0007266320.074
ribonucleoside metabolic processGO:00091192450.074
ribonucleotide metabolic processGO:00092592910.073
cellular nitrogen compound catabolic processGO:00442702800.071
purine containing compound catabolic processGO:00725232130.071
regulation of cellular ketone metabolic processGO:0010565660.071
purine ribonucleoside triphosphate metabolic processGO:00092052200.071
glycosyl compound metabolic processGO:19016572460.069
cellular amino acid metabolic processGO:00065201030.068
purine containing compound metabolic processGO:00725213110.068
nucleoside metabolic processGO:00091162460.067
purine nucleoside metabolic processGO:00422782410.067
purine ribonucleoside catabolic processGO:00461302050.066
nucleoside triphosphate metabolic processGO:00091412300.066
ribonucleoside catabolic processGO:00424542060.065
aromatic compound catabolic processGO:00194392860.065
ras protein signal transductionGO:0007265770.064
glycosyl compound catabolic processGO:19016582060.062
nucleoside phosphate metabolic processGO:00067533380.061
regulation of nucleotide metabolic processGO:00061401690.060
regulation of hydrolase activityGO:00513362460.060
guanosine containing compound metabolic processGO:19010681440.060
purine nucleoside triphosphate catabolic processGO:00091462030.058
purine nucleoside triphosphate metabolic processGO:00091442260.057
purine ribonucleotide catabolic processGO:00091542080.056
cellular ketone metabolic processGO:0042180840.056
guanosine containing compound catabolic processGO:19010691440.056
ribonucleoside triphosphate catabolic processGO:00092031990.056
regulation of cellular amino acid metabolic processGO:000652150.055
ribonucleoside triphosphate metabolic processGO:00091992200.055
amine metabolic processGO:0009308450.055
organic cyclic compound catabolic processGO:19013612950.055
carbohydrate derivative catabolic processGO:19011362310.053
purine ribonucleoside metabolic processGO:00461282410.052
regulation of nucleoside metabolic processGO:00091181300.051
purine ribonucleoside triphosphate catabolic processGO:00092071990.051
nucleotide catabolic processGO:00091662170.051
cellular amine metabolic processGO:0044106440.050
regulation of cellular catabolic processGO:00313292420.050
regulation of cellular amine metabolic processGO:0033238200.049
nucleoside triphosphate catabolic processGO:00091432050.047
positive regulation of purine nucleotide metabolic processGO:19005441140.047
regulation of purine nucleotide metabolic processGO:19005421690.046
axonogenesisGO:00074092740.046
positive regulation of gtp catabolic processGO:0033126850.045
organophosphate catabolic processGO:00464342320.044
ribonucleotide catabolic processGO:00092612080.043
regulation of gtp catabolic processGO:00331241130.043
chemotaxisGO:00069352470.043
positive regulation of cellular catabolic processGO:00313311480.042
negative regulation of cell proliferationGO:00082852960.042
mapk cascadeGO:00001652810.042
positive regulation of hydrolase activityGO:00513451480.041
cation transportGO:00068123990.041
positive regulation of nucleoside metabolic processGO:0045979910.040
angiogenesisGO:00015252010.040
regulation of organelle organizationGO:00330432890.039
cell adhesionGO:00071553290.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
oxidation reduction processGO:00551143420.037
muscle cell differentiationGO:00426922610.037
gtp catabolic processGO:00061841430.037
regulation of mapk cascadeGO:00434082480.037
membrane organizationGO:00610242450.037
regulation of nucleotide catabolic processGO:00308111220.035
positive regulation of ras gtpase activityGO:0032320650.034
regulation of purine nucleotide catabolic processGO:00331211220.033
synaptic transmissionGO:00072683290.033
positive regulation of purine nucleotide catabolic processGO:0033123880.033
negative regulation of protein metabolic processGO:00512482820.033
regulation of system processGO:00440572000.032
cellular homeostasisGO:00197252400.032
forebrain developmentGO:00309003020.031
g protein coupled receptor signaling pathwayGO:00071862430.031
regulation of ras gtpase activityGO:0032318880.031
response to organonitrogen compoundGO:00102432460.031
positive regulation of nucleotide metabolic processGO:00459811140.031
peptidyl amino acid modificationGO:00181933360.030
telencephalon developmentGO:00215371860.030
negative regulation of cellular component organizationGO:00511291940.030
regulation of cell motilityGO:20001452360.030
negative regulation of cellular protein metabolic processGO:00322692470.029
multicellular organismal signalingGO:0035637910.029
fat cell differentiationGO:00454441600.029
cellular lipid metabolic processGO:00442553230.028
blood vessel morphogenesisGO:00485142850.028
regulation of anatomical structure sizeGO:00900661780.027
positive regulation of nucleotide catabolic processGO:0030813880.027
regulation of protein kinase activityGO:00458592320.027
nitrogen compound transportGO:00717052710.026
carbohydrate derivative biosynthetic processGO:19011371830.026
wnt signaling pathwayGO:00160551880.026
regulation of cell projection organizationGO:00313442060.026
regulation of cell activationGO:00508652890.026
regulation of rho gtpase activityGO:0032319580.026
positive regulation of protein modification processGO:00314012990.026
microtubule based processGO:00070172360.026
regulation of neuron differentiationGO:00456642810.025
myeloid cell differentiationGO:00300992330.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
positive regulation of cellular amine metabolic processGO:003324050.025
muscle system processGO:00030121410.024
positive regulation of protein phosphorylationGO:00019342420.024
positive regulation of gtpase activityGO:0043547850.024
ion transmembrane transportGO:00342203610.023
lymphocyte differentiationGO:00300982420.023
dephosphorylationGO:00163111290.023
positive regulation of rho gtpase activityGO:0032321410.023
regulation of kinase activityGO:00435492490.023
immune effector processGO:00022523210.023
regulation of ras protein signal transductionGO:00465781140.023
negative regulation of cellular amino acid metabolic processGO:004576300.023
positive regulation of cell developmentGO:00107202370.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
male gamete generationGO:00482322850.022
spermatogenesisGO:00072832840.022
carbohydrate metabolic processGO:00059752300.022
negative regulation of molecular functionGO:00440922580.022
camera type eye developmentGO:00430102660.022
regulation of membrane potentialGO:00423911920.022
cellular response to lipidGO:00713961450.022
posttranscriptional regulation of gene expressionGO:00106081550.021
sensory perceptionGO:00076002450.021
regulation of rho protein signal transductionGO:0035023710.021
negative regulation of protein phosphorylationGO:00019331260.021
regulation of cell migrationGO:00303342190.021
regulation of homeostatic processGO:00328441820.021
regulation of cytoskeleton organizationGO:00514931220.021
cation homeostasisGO:00550802120.021
positive regulation of nervous system developmentGO:00519622210.021
transmembrane transportGO:00550854120.021
regulation of transferase activityGO:00513382630.021
dendrite developmentGO:00163581150.021
cellular response to organonitrogen compoundGO:00714171450.020
positive regulation of mapk cascadeGO:00434101700.020
leukocyte migrationGO:00509001240.020
axon guidanceGO:00074111410.020
regulation of hormone levelsGO:00108172110.020
hematopoietic progenitor cell differentiationGO:00022441430.020
macromolecule catabolic processGO:00090572810.020
skeletal system developmentGO:00015013560.020
transmission of nerve impulseGO:0019226760.020
protein catabolic processGO:00301632210.020
developmental maturationGO:00217001930.020
urogenital system developmentGO:00016552610.020
ossificationGO:00015032160.020
regulation of cell adhesionGO:00301551540.020
organonitrogen compound biosynthetic processGO:19015661920.019
sequestering of calcium ionGO:0051208180.019
striated muscle tissue developmentGO:00147062930.019
retina development in camera type eyeGO:00600411190.019
rhythmic processGO:00485111740.019
compound eye developmentGO:004874910.019
muscle tissue developmentGO:00605373080.019
glycoprotein metabolic processGO:00091001160.019
synapse organizationGO:00508081250.019
muscle contractionGO:00069361010.019
circulatory system processGO:00030131970.019
dna metabolic processGO:00062593030.019
organelle assemblyGO:00709251770.018
protein localization to membraneGO:00726571080.018
maintenance of locationGO:0051235890.018
sensory organ morphogenesisGO:00905962420.018
negative regulation of cellular amine metabolic processGO:003323910.018
regulation of proteolysisGO:00301621640.018
leukocyte proliferationGO:00706611720.018
organelle localizationGO:00516401790.018
leukocyte differentiationGO:00025213420.018
developmental growth involved in morphogenesisGO:00605601380.018
regulation of actin filament based processGO:0032970990.018
cellular chemical homeostasisGO:00550822150.018
epithelial tube morphogenesisGO:00605623030.018
regulation of blood circulationGO:1903522930.017
regulation of vesicle mediated transportGO:00606271390.017
blood circulationGO:00080151950.017
organic hydroxy compound metabolic processGO:19016152030.017
regulation of cell morphogenesis involved in differentiationGO:00107691510.017
leukocyte mediated immunityGO:00024431740.017
t cell activationGO:00421102890.017
muscle cell developmentGO:00550011330.017
cellular protein complex assemblyGO:00436231160.017
glucose homeostasisGO:00425931280.017
protein modification by small protein conjugationGO:00324461870.017
striated muscle cell developmentGO:00550021250.017
response to organic cyclic compoundGO:00140701980.017
germ cell developmentGO:00072811850.017
regulation of cellular component biogenesisGO:00440871810.017
positive regulation of cell deathGO:00109422240.017
cation transmembrane transportGO:00986552660.017
single organism cell adhesionGO:00986021560.017
reactive oxygen species metabolic processGO:0072593840.017
morphogenesis of embryonic epitheliumGO:00163311590.017
regulation of secretion by cellGO:19035302490.017
inorganic ion transmembrane transportGO:00986602340.017
negative regulation of protein modification processGO:00314001630.017
stem cell differentiationGO:00488632680.016
cytokine productionGO:00018163190.016
embryonic epithelial tube formationGO:00018381300.016
apoptotic signaling pathwayGO:00971903060.016
protein maturationGO:00516041760.016
protein ubiquitinationGO:00165671710.016
negative regulation of phosphate metabolic processGO:00459361840.016
negative regulation of phosphorus metabolic processGO:00105631840.016
endocytosisGO:00068971680.016
renal system developmentGO:00720012250.016
myeloid cell homeostasisGO:00022621140.016
cell activation involved in immune responseGO:00022631260.016
regulation of cell cycleGO:00517262810.016
neuronal action potentialGO:0019228540.016
protein modification by small protein conjugation or removalGO:00706472070.016
actin cytoskeleton organizationGO:00300362200.016
response to molecule of bacterial originGO:00022371430.016
respiratory system developmentGO:00605411900.016
response to extracellular stimulusGO:00099911270.015
spermatid differentiationGO:00485151150.015
negative regulation of synapse assemblyGO:005196430.015
positive regulation of transferase activityGO:00513471670.015
regulation of cellular component sizeGO:00325351210.015
cellular response to dna damage stimulusGO:00069742070.015
regulation of body fluid levelsGO:00508781620.015
locomotory behaviorGO:00076261950.015
cell chemotaxisGO:0060326810.015
respiratory tube developmentGO:00303231670.015
regulation of cytokine productionGO:00018172660.015
carbohydrate homeostasisGO:00335001280.015
metal ion homeostasisGO:00550651890.015
leukocyte activation involved in immune responseGO:00023661260.015
positive regulation of protein kinase activityGO:00458601440.015
skeletal muscle organ developmentGO:00605381630.015
regulation of ion transportGO:00432692150.015
regionalizationGO:00030023370.015
divalent metal ion transportGO:00708381720.015
inflammatory responseGO:00069542440.015
tissue homeostasisGO:00018941150.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
fertilizationGO:00095661270.015
kidney developmentGO:00018222130.015
response to acid chemicalGO:00011011110.015
morphogenesis of a branching structureGO:00017632030.015
regulation of apoptotic signaling pathwayGO:20012331970.014
cellular macromolecule catabolic processGO:00442652060.014
cytoplasmic transportGO:00164822340.014
cell type specific apoptotic processGO:00972852680.014
anion transportGO:00068201770.014
negative regulation of nervous system developmentGO:00519611560.014
pallium developmentGO:00215431200.014
gland developmentGO:00487323300.014
central nervous system neuron differentiationGO:00219531620.014
positive regulation of neuron differentiationGO:00456661410.014
regulation of cellular response to stressGO:00801351590.014
heart contractionGO:0060047930.014
neural tube developmentGO:00219151600.014
protein processingGO:00164851630.014
sequestering of metal ionGO:0051238190.014
negative regulation of intracellular signal transductionGO:19025321670.014
regulation of response to woundingGO:19030341890.014
endomembrane system organizationGO:00102561470.014
anatomical structure homeostasisGO:00602491450.014
engulfment of apoptotic cellGO:004365230.014
cell cell junction organizationGO:0045216720.014
lymphocyte proliferationGO:00466511640.014
stem cell developmentGO:00488642190.014
inorganic cation transmembrane transportGO:00986622070.014
negative regulation of neuron differentiationGO:00456651010.014
regulation of secretionGO:00510462740.014
divalent inorganic cation transportGO:00725111780.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
action potentialGO:0001508780.014
multicellular organismal homeostasisGO:00488711640.014
nuclear divisionGO:00002801580.014
cellular component assembly involved in morphogenesisGO:00109271390.014
cognitionGO:00508901490.013
epithelial cell developmentGO:00020641590.013
lateral inhibitionGO:004633110.013
glycoprotein biosynthetic processGO:0009101890.013
primary neural tube formationGO:0014020950.013
response to lipopolysaccharideGO:00324961280.013
negative regulation of phosphorylationGO:00423261660.013
lung developmentGO:00303241640.013
regulation of striated muscle cell differentiationGO:0051153810.013
chromatin organizationGO:00063252060.013
neuron deathGO:00709971540.013
exocytosisGO:00068871210.013
glial cell differentiationGO:00100011310.013
positive regulation of programmed cell deathGO:00430682180.013
actin filament organizationGO:00070151130.013
regulation of lymphocyte activationGO:00512492400.013
regulation of epithelial cell proliferationGO:00506781410.013
homeostasis of number of cellsGO:00488722100.013
multi multicellular organism processGO:00447061090.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
myeloid leukocyte migrationGO:0097529570.013
heart processGO:0003015940.013
generation of precursor metabolites and energyGO:00060911030.013
response to growth factorGO:00708481980.013
peptidyl tyrosine phosphorylationGO:00181081430.013
cell growthGO:00160491300.013
neuron migrationGO:00017641220.013
response to radiationGO:00093141650.013
regulation of muscle system processGO:0090257800.013
regulation of transmembrane transportGO:00347621280.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
neuron projection guidanceGO:00974851410.013
cellular ion homeostasisGO:00068731650.013
regulation of protein localizationGO:00328802310.013
detection of stimulusGO:0051606840.013
rap protein signal transductionGO:003248630.013
organic hydroxy compound transportGO:0015850930.012
lipid biosynthetic processGO:00086101790.012
regulation of map kinase activityGO:00434051200.012
response to peptide hormoneGO:00434341270.012
regulation of protein catabolic processGO:00421761080.012
positive regulation of protein serine threonine kinase activityGO:00719021060.012
regulation of protein complex assemblyGO:0043254830.012
negative regulation of growthGO:0045926990.012
immune response activating signal transductionGO:00027571160.012
epithelial cell proliferationGO:00506731740.012
retina morphogenesis in camera type eyeGO:0060042450.012
small molecule biosynthetic processGO:00442831320.012
amide transportGO:00428861380.012
regulation of bindingGO:00510981110.012
positive regulation of smooth muscle cell migrationGO:001491140.012
cellular response to hormone stimulusGO:00328701500.012
defense response to other organismGO:00985421970.012
cellular response to biotic stimulusGO:0071216920.012
microtubule cytoskeleton organizationGO:00002261570.012
b cell activationGO:00421131610.012
regulation of intracellular transportGO:00323861590.012
plasma membrane organizationGO:0007009900.012
regulation of neuron projection developmentGO:00109751690.012
cell substrate adhesionGO:00315891300.012
morphogenesis of a branching epitheliumGO:00611381930.012
cellular metal ion homeostasisGO:00068751510.012
macromolecule methylationGO:00434141200.012
regulation of neuron apoptotic processGO:00435231220.012
regulation of vasculature developmentGO:1901342880.012
organelle fissionGO:00482851700.012
response to nutrient levelsGO:00316671090.012
organophosphate biosynthetic processGO:00904071220.012
regulation of protein serine threonine kinase activityGO:00719001570.012
sensory perception of mechanical stimulusGO:00509541070.012
mitotic cell cycle processGO:19030471590.012
response to light stimulusGO:00094161350.012
lymphocyte mediated immunityGO:00024491390.012
protein localization to organelleGO:00333651850.012
calcium ion transportGO:00068161590.012
pigmentationGO:0043473710.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
cellular response to extracellular stimulusGO:0031668810.012
extracellular structure organizationGO:00430621480.012
hindbrain developmentGO:00309021280.012
regulation of cell cycle processGO:00105641600.012
intracellular protein transportGO:00068862040.012
mitotic cell cycleGO:00002781950.011
second messenger mediated signalingGO:0019932730.011
rna processingGO:00063961050.011
calcium ion homeostasisGO:00550741270.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
axon ensheathmentGO:0008366760.011
regulation of cell growthGO:0001558910.011
localization within membraneGO:005166840.011
placenta developmentGO:00018901400.011
regulation of heart contractionGO:0008016770.011
regulation of endocytosisGO:0030100690.011
regulation of neuron deathGO:19012141340.011
development of primary male sexual characteristicsGO:0046546880.011
positive regulation of secretion by cellGO:19035321140.011
digestive tract developmentGO:00485651900.011
mesodermal cell migrationGO:000807840.011
methylationGO:00322591340.011
lipid transportGO:0006869980.011
tube closureGO:0060606910.011
neural tube formationGO:00018411080.011
sympathetic neuron projection extensionGO:009749040.011
innate immune responseGO:00450871570.011
positive regulation of cell activationGO:00508671580.011
positive regulation of kinase activityGO:00336741550.011
midgut developmentGO:000749440.011
monocarboxylic acid metabolic processGO:00327871910.011
epidermis developmentGO:00085441870.011
negative regulation of cell developmentGO:00107211690.011
epithelial cell migrationGO:0010631630.011
peptide hormone secretionGO:00300721090.011
negative regulation of cell migrationGO:0030336590.011
regulation of cell sizeGO:0008361720.011
negative regulation of endothelial cell migrationGO:001059640.011
regulation of chemotaxisGO:0050920530.011
regulation of ion transmembrane transportGO:00347651190.011
multicellular organism growthGO:00352641610.011
cellular response to molecule of bacterial originGO:0071219830.011
sympathetic neuron projection guidanceGO:009749140.011
response to peptideGO:19016521360.011
positive regulation of cell motilityGO:20001471160.011
mrna metabolic processGO:0016071840.011
actin filament based movementGO:0030048230.011
chromatin modificationGO:00165681870.011
regulation of lipid metabolic processGO:00192161180.011
positive regulation of secretionGO:00510471300.011
extracellular matrix organizationGO:00301981470.011
cellular response to acid chemicalGO:0071229680.011
negative regulation of organelle organizationGO:0010639900.011
cellular response to organic cyclic compoundGO:0071407870.011
covalent chromatin modificationGO:00165691630.011
nucleoside phosphate biosynthetic processGO:1901293790.011
negative regulation of transferase activityGO:0051348850.011
nucleotide biosynthetic processGO:0009165780.011
mitotic cytokinesisGO:000028140.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
immune response regulating signaling pathwayGO:00027641250.011
cytokine mediated signaling pathwayGO:00192211150.011
positive regulation of phospholipase activityGO:001051830.010
ameboidal type cell migrationGO:00016671280.010
negative regulation of immune system processGO:00026832090.010
modification dependent protein catabolic processGO:00199411330.010
reactive nitrogen species metabolic processGO:200105700.010
cellular calcium ion homeostasisGO:00068741190.010
tube formationGO:00351481400.010
skin developmentGO:00435882200.010
regulation of metal ion transportGO:00109591060.010
adult behaviorGO:00305341350.010
cellular protein catabolic processGO:00442571550.010
leukocyte chemotaxisGO:0030595690.010
ear developmentGO:00435832000.010
spermatid developmentGO:00072861080.010
cell maturationGO:00484691270.010
epithelial tube formationGO:00721751300.010
divalent inorganic cation homeostasisGO:00725071380.010
regulation of muscle tissue developmentGO:1901861970.010
meiotic nuclear divisionGO:00071261150.010
myeloid leukocyte differentiationGO:00025731190.010
regulation of phospholipase c activityGO:190027430.010
protein glycosylationGO:0006486550.010
cell junction organizationGO:0034330770.010
canonical wnt signaling pathwayGO:00600701300.010
peptide transportGO:00158331330.010
neuron apoptotic processGO:00514021420.010
sensory perception of soundGO:0007605970.010

Hecw2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
nervous system diseaseDOID:86300.066
central nervous system diseaseDOID:33100.028
brain diseaseDOID:93600.012
immune system diseaseDOID:291400.011
organ system cancerDOID:005068600.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
neurodegenerative diseaseDOID:128900.010