IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Gabra2

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2

(Aliases: C630048P16Rik,MGC140832,Gabra-2)

Ensembl: ENSMUSG00000000560
Entrez: 14395
UniProtKB: Q544G1
UniProtKB: P26048

Process Predictions
Disease Predictions

Gabra2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
synaptic transmission	GO:0007268	329	0.886	Mouse
associative learning	GO:0008306	61	0.825	Mouse
multicellular organismal response to stress	GO:0033555	62	0.814	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.808	Mouse
transmembrane transport	GO:0055085	412	0.808	Mouse
locomotory behavior	GO:0007626	195	0.806	Mouse
ion transmembrane transport	GO:0034220	361	0.770	Mouse
regulation of membrane potential	GO:0042391	192	0.760	Mouse
fear response	GO:0042596	33	0.671	Mouse
nerve development	GO:0021675	67	0.660	Mouse
forebrain development	GO:0030900	302	0.646
neuronal action potential	GO:0019228	54	0.644
neuron neuron synaptic transmission	GO:0007270	69	0.630	Mouse
transmission of nerve impulse	GO:0019226	76	0.617
regulation of neuron apoptotic process	GO:0043523	122	0.610	Mouse
mechanoreceptor differentiation	GO:0042490	67	0.604	Mouse
regulation of neuron death	GO:1901214	134	0.539	Mouse
regulation of neuron differentiation	GO:0045664	281	0.539
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.538
regulation of synaptic plasticity	GO:0048167	87	0.525
reflex	GO:0060004	22	0.517	Mouse
negative regulation of neuron death	GO:1901215	98	0.511	Mouse
dendrite development	GO:0016358	115	0.502
axonogenesis	GO:0007409	274	0.499
inorganic ion transmembrane transport	GO:0098660	234	0.466	Mouse
action potential	GO:0001508	78	0.465	Mouse
glutamate receptor signaling pathway	GO:0007215	35	0.463
multicellular organismal signaling	GO:0035637	91	0.461
telencephalon development	GO:0021537	186	0.445
cognition	GO:0050890	149	0.437	Mouse
regulation of neuron projection development	GO:0010975	169	0.432
adult behavior	GO:0030534	135	0.428	Mouse
regulation of hormone levels	GO:0010817	211	0.423
gliogenesis	GO:0042063	141	0.423
gamma aminobutyric acid signaling pathway	GO:0007214	8	0.409	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.409
learning or memory	GO:0007611	148	0.403	Mouse
glial cell differentiation	GO:0010001	131	0.401
cellular response to histamine	GO:0071420	1	0.396	Mouse
sensory perception	GO:0007600	245	0.394	Mouse
learning	GO:0007612	98	0.384	Mouse
regulation of long term neuronal synaptic plasticity	GO:0048169	19	0.381
dendritic spine development	GO:0060996	30	0.379
regulation of cell projection organization	GO:0031344	206	0.373
regulation of ion transport	GO:0043269	215	0.372
cellular amine metabolic process	GO:0044106	44	0.358
inner ear receptor cell differentiation	GO:0060113	61	0.355	Mouse
central nervous system neuron development	GO:0021954	67	0.355
cell adhesion	GO:0007155	329	0.352
regulation of neuronal synaptic plasticity	GO:0048168	30	0.349
nitrogen compound transport	GO:0071705	271	0.348
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.337
neuron death	GO:0070997	154	0.328	Mouse
positive regulation of nervous system development	GO:0051962	221	0.323
regulation of system process	GO:0044057	200	0.314	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.310
inorganic cation transmembrane transport	GO:0098662	207	0.302
righting reflex	GO:0060013	9	0.300	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.295
sensory perception of pain	GO:0019233	47	0.291
cation transmembrane transport	GO:0098655	266	0.290
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.288
developmental maturation	GO:0021700	193	0.282
ear development	GO:0043583	200	0.281	Mouse
neuron apoptotic process	GO:0051402	142	0.276	Mouse
cation transport	GO:0006812	399	0.271
response to organonitrogen compound	GO:0010243	246	0.270	Mouse
long term synaptic potentiation	GO:0060291	25	0.264
behavioral fear response	GO:0001662	28	0.260	Mouse
visual perception	GO:0007601	52	0.254	Mouse
activation of adenylate cyclase activity	GO:0007190	4	0.250
divalent inorganic cation transport	GO:0072511	178	0.246
guanosine containing compound metabolic process	GO:1901068	144	0.246
regulation of cellular amino acid metabolic process	GO:0006521	5	0.245
adult walking behavior	GO:0007628	41	0.243	Mouse
inner ear receptor cell development	GO:0060119	39	0.240	Mouse
regulation of g protein activated inward rectifier potassium channel activity	GO:1900128	1	0.238
skeletal system development	GO:0001501	356	0.237
response to organic cyclic compound	GO:0014070	198	0.229	Mouse
camera type eye development	GO:0043010	266	0.228
blood circulation	GO:0008015	195	0.226
positive regulation of long term neuronal synaptic plasticity	GO:0048170	3	0.221
anion transport	GO:0006820	177	0.221	Mouse
insulin secretion	GO:0030073	89	0.220
response to radiation	GO:0009314	165	0.213
innervation	GO:0060384	22	0.212	Mouse
neuron projection guidance	GO:0097485	141	0.211
regulation of cellular amine metabolic process	GO:0033238	20	0.209
second messenger mediated signaling	GO:0019932	73	0.208
negative regulation of cell proliferation	GO:0008285	296	0.208
organic hydroxy compound metabolic process	GO:1901615	203	0.203
cellular ketone metabolic process	GO:0042180	84	0.202
response to pain	GO:0048265	26	0.199
palate development	GO:0060021	76	0.196	Mouse
blood vessel morphogenesis	GO:0048514	285	0.195
behavioral defense response	GO:0002209	28	0.195	Mouse
multicellular organism growth	GO:0035264	161	0.191
response to ammonium ion	GO:0060359	21	0.189	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.189
purine containing compound metabolic process	GO:0072521	311	0.188
adult locomotory behavior	GO:0008344	91	0.188	Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.185
amide transport	GO:0042886	138	0.183
ensheathment of neurons	GO:0007272	76	0.183
regulation of postsynaptic membrane potential	GO:0060078	48	0.182	Mouse
amino acid transport	GO:0006865	61	0.178
synapse organization	GO:0050808	125	0.177
peptide transport	GO:0015833	133	0.176
synaptic transmission glycinergic	GO:0060012	2	0.174	Mouse
membrane depolarization	GO:0051899	64	0.173
regulation of nucleoside metabolic process	GO:0009118	130	0.171
myeloid leukocyte differentiation	GO:0002573	119	0.169
regulation of secretion by cell	GO:1903530	249	0.168
regulation of body fluid levels	GO:0050878	162	0.167
nucleotide metabolic process	GO:0009117	332	0.165
cell type specific apoptotic process	GO:0097285	268	0.161	Mouse
forebrain neuron differentiation	GO:0021879	52	0.161
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.160
cellular response to ammonium ion	GO:0071242	2	0.160	Mouse
regulation of dendritic spine morphogenesis	GO:0061001	17	0.159
myeloid cell differentiation	GO:0030099	233	0.158
heart morphogenesis	GO:0003007	178	0.157
organonitrogen compound biosynthetic process	GO:1901566	192	0.157
fasciculation of sensory neuron axon	GO:0097155	3	0.156
neuron migration	GO:0001764	122	0.154
positive regulation of neuron differentiation	GO:0045666	141	0.153
limbic system development	GO:0021761	72	0.153
stem cell differentiation	GO:0048863	268	0.152
membrane organization	GO:0061024	245	0.148
axonal fasciculation	GO:0007413	15	0.146
regulation of ovulation	GO:0060278	3	0.146
rhythmic process	GO:0048511	174	0.146
sensory perception of light stimulus	GO:0050953	54	0.142	Mouse
axon guidance	GO:0007411	141	0.140
nucleoside metabolic process	GO:0009116	246	0.139
gtp metabolic process	GO:0046039	144	0.138
positive regulation of camp metabolic process	GO:0030816	19	0.137
angiogenesis	GO:0001525	201	0.137
negative regulation of neuron apoptotic process	GO:0043524	92	0.137	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.136
leukocyte differentiation	GO:0002521	342	0.135
response to light stimulus	GO:0009416	135	0.133
carbohydrate metabolic process	GO:0005975	230	0.132
organic hydroxy compound transport	GO:0015850	93	0.132
positive regulation of heart rate by epinephrine norepinephrine	GO:0001996	4	0.131
ribose phosphate metabolic process	GO:0019693	291	0.131
ribonucleotide metabolic process	GO:0009259	291	0.130
glucose homeostasis	GO:0042593	128	0.130
oligodendrocyte development	GO:0014003	20	0.130
nucleoside phosphate metabolic process	GO:0006753	338	0.130
amine metabolic process	GO:0009308	45	0.129
neuromuscular process	GO:0050905	99	0.128	Mouse
peptide hormone secretion	GO:0030072	109	0.128
peptide secretion	GO:0002790	114	0.125
retinal cone cell development	GO:0046549	8	0.125
bone development	GO:0060348	120	0.124
oligodendrocyte differentiation	GO:0048709	53	0.123
cell maturation	GO:0048469	127	0.123
regulation of transmembrane transport	GO:0034762	128	0.122
regulation of cellular catabolic process	GO:0031329	242	0.122
neuron maturation	GO:0042551	29	0.122
sensory perception of sound	GO:0007605	97	0.120	Mouse
negative regulation of ovulation	GO:0060280	1	0.120
regulation of purine nucleotide metabolic process	GO:1900542	169	0.120
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.120
digestion	GO:0007586	40	0.117
cellular response to organonitrogen compound	GO:0071417	145	0.116	Mouse
regulation of purine nucleotide catabolic process	GO:0033121	122	0.115
regulation of response to drug	GO:2001023	2	0.114	Mouse
visual behavior	GO:0007632	45	0.113
neural retina development	GO:0003407	41	0.111
epithelial cell development	GO:0002064	159	0.110
regulation of organelle organization	GO:0033043	289	0.109
hippocampus development	GO:0021766	52	0.109
forebrain generation of neurons	GO:0021872	63	0.109
cell recognition	GO:0008037	83	0.107
positive regulation of cell development	GO:0010720	237	0.106
hormone secretion	GO:0046879	128	0.106
embryonic organ morphogenesis	GO:0048562	276	0.106
peptidyl amino acid modification	GO:0018193	336	0.106
response to histamine	GO:0034776	1	0.104	Mouse
stem cell development	GO:0048864	219	0.103
retinal ganglion cell axon guidance	GO:0031290	18	0.103
cellular carbohydrate metabolic process	GO:0044262	119	0.102
ear morphogenesis	GO:0042471	118	0.102
regulation of nucleotide catabolic process	GO:0030811	122	0.101
regulation of kinase activity	GO:0043549	249	0.101
negative regulation of bone trabecula formation	GO:1900155	1	0.100
gland development	GO:0048732	330	0.099
nucleobase containing small molecule metabolic process	GO:0055086	352	0.098
habituation	GO:0046959	3	0.097
memory	GO:0007613	58	0.097
ossification	GO:0001503	216	0.097
neural tube development	GO:0021915	160	0.097
chemotaxis	GO:0006935	247	0.097
positive regulation of programmed cell death	GO:0043068	218	0.096
cerebral cortex gabaergic interneuron migration	GO:0021853	6	0.096
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure	GO:0002025	3	0.096
single organism cell adhesion	GO:0098602	156	0.095
forebrain neuron development	GO:0021884	30	0.095
regulation of neurotransmitter transport	GO:0051588	35	0.094
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	24	0.094
phenol containing compound metabolic process	GO:0018958	60	0.093
axon ensheathment	GO:0008366	76	0.093
cellular homeostasis	GO:0019725	240	0.093
purine nucleotide metabolic process	GO:0006163	302	0.093
visual learning	GO:0008542	44	0.092
rho protein signal transduction	GO:0007266	32	0.089
regulation of dendritic spine development	GO:0060998	22	0.089
central nervous system neuron axonogenesis	GO:0021955	28	0.088
nucleoside phosphate biosynthetic process	GO:1901293	79	0.088
regulation of hydrolase activity	GO:0051336	246	0.088
fasciculation of motor neuron axon	GO:0097156	2	0.088
regulation of cell motility	GO:2000145	236	0.087
myelination	GO:0042552	74	0.087
regulation of nucleotide metabolic process	GO:0006140	169	0.086
camp mediated signaling	GO:0019933	15	0.085
regulation of heart contraction	GO:0008016	77	0.085
nucleoside catabolic process	GO:0009164	206	0.084
astrocyte differentiation	GO:0048708	43	0.084
regulation of gtp catabolic process	GO:0033124	113	0.084
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	30	0.083
retina development in camera type eye	GO:0060041	119	0.083
positive regulation of the force of heart contraction by epinephrine norepinephrine	GO:0001997	3	0.083
regulation of hormone secretion	GO:0046883	88	0.083
hormone metabolic process	GO:0042445	86	0.082
regulation of peptide secretion	GO:0002791	77	0.082
ras protein signal transduction	GO:0007265	77	0.082
regulation of homeostatic process	GO:0032844	182	0.081
dendritic spine morphogenesis	GO:0060997	22	0.081
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.080
regulation of vesicle mediated transport	GO:0060627	139	0.080
neuron recognition	GO:0008038	25	0.080
cellular chemical homeostasis	GO:0055082	215	0.080
pallium development	GO:0021543	120	0.079
cellular response to temperature stimulus	GO:0071502	2	0.078
phospholipase c activating serotonin receptor signaling pathway	GO:0007208	1	0.078
actin filament organization	GO:0007015	113	0.077
gtp catabolic process	GO:0006184	143	0.077
mapk cascade	GO:0000165	281	0.077
regulation of secretion	GO:0051046	274	0.076
sodium ion transport	GO:0006814	73	0.076
skeletal system morphogenesis	GO:0048705	203	0.076
catecholamine metabolic process	GO:0006584	30	0.076
purine ribonucleotide metabolic process	GO:0009150	290	0.076
regulation of cellular component biogenesis	GO:0044087	181	0.075
synaptic transmission glutamatergic	GO:0035249	36	0.075
regulation of cellular response to stress	GO:0080135	159	0.075
calcium ion homeostasis	GO:0055074	127	0.075
sensory perception of mechanical stimulus	GO:0050954	107	0.074	Mouse
response to growth factor	GO:0070848	198	0.074
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.073
appendage development	GO:0048736	166	0.073
kidney development	GO:0001822	213	0.073
l amino acid transport	GO:0015807	32	0.073
cyclic purine nucleotide metabolic process	GO:0052652	43	0.072
ribonucleotide biosynthetic process	GO:0009260	59	0.071
endocytosis	GO:0006897	168	0.071
retina morphogenesis in camera type eye	GO:0060042	45	0.071
guanosine containing compound catabolic process	GO:1901069	144	0.071
regulation of protein kinase activity	GO:0045859	232	0.070
nucleotide biosynthetic process	GO:0009165	78	0.070
purine nucleotide biosynthetic process	GO:0006164	65	0.070
positive regulation of transferase activity	GO:0051347	167	0.070
mesenchymal cell differentiation	GO:0048762	107	0.069
positive regulation of neuron projection development	GO:0010976	79	0.068
oxidation reduction process	GO:0055114	342	0.068
central nervous system projection neuron axonogenesis	GO:0021952	21	0.068
neuron projection extension	GO:1990138	64	0.068
apoptotic signaling pathway	GO:0097190	306	0.068
positive regulation of cellular amine metabolic process	GO:0033240	5	0.068
corpus callosum development	GO:0022038	10	0.067
mesenchymal cell development	GO:0014031	93	0.067
purine ribonucleoside metabolic process	GO:0046128	241	0.067
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.067
positive regulation of apoptotic process	GO:0043065	217	0.066
regulation of ion transmembrane transport	GO:0034765	119	0.066
regulation of rac gtpase activity	GO:0032314	13	0.066
anion transmembrane transport	GO:0098656	71	0.066	Mouse
digestive tract morphogenesis	GO:0048546	147	0.066
negative regulation of reproductive process	GO:2000242	31	0.065
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.065
rac protein signal transduction	GO:0016601	13	0.065
cellular potassium ion transport	GO:0071804	43	0.065
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.064
regulation of cell migration	GO:0030334	219	0.064
embryonic epithelial tube formation	GO:0001838	130	0.064
cation homeostasis	GO:0055080	212	0.064
sodium ion transmembrane transport	GO:0035725	49	0.063
sensory organ morphogenesis	GO:0090596	242	0.063
mitral valve development	GO:0003174	4	0.062
purine nucleotide catabolic process	GO:0006195	211	0.062
positive regulation of protein modification process	GO:0031401	299	0.061
detection of stimulus	GO:0051606	84	0.061
purine ribonucleotide catabolic process	GO:0009154	208	0.061
negative regulation of multi organism process	GO:0043901	68	0.060
male gamete generation	GO:0048232	285	0.060
positive regulation of nucleotide metabolic process	GO:0045981	114	0.060
glial cell development	GO:0021782	54	0.060
protein localization to membrane	GO:0072657	108	0.060
positive regulation of organelle organization	GO:0010638	128	0.060
calcium mediated signaling	GO:0019722	46	0.059
somatostatin receptor signaling pathway	GO:0038169	2	0.059
purine nucleoside metabolic process	GO:0042278	241	0.059
digestive system development	GO:0055123	200	0.059
cranial nerve development	GO:0021545	41	0.058
purine ribonucleoside catabolic process	GO:0046130	205	0.058
synaptic transmission gabaergic	GO:0051932	19	0.058
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.057
single organismal cell cell adhesion	GO:0016337	131	0.057
negative regulation of protein metabolic process	GO:0051248	282	0.057
regulation of glutamate receptor signaling pathway	GO:1900449	16	0.057
response to steroid hormone	GO:0048545	56	0.057
regulation of feeding behavior	GO:0060259	3	0.057
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.057
regulation of cell adhesion	GO:0030155	154	0.057
body morphogenesis	GO:0010171	45	0.057
endomembrane system organization	GO:0010256	147	0.056
regulation of actin filament based process	GO:0032970	99	0.056
heart contraction	GO:0060047	93	0.055
g protein coupled receptor internalization	GO:0002031	3	0.055
asymmetric neuroblast division	GO:0055059	1	0.055
camp biosynthetic process	GO:0006171	31	0.055
skin development	GO:0043588	220	0.055
cerebral cortex development	GO:0021987	86	0.055
ribonucleoside catabolic process	GO:0042454	206	0.054
motor neuron axon guidance	GO:0008045	26	0.054
nucleotide catabolic process	GO:0009166	217	0.054
positive regulation of purine nucleotide biosynthetic process	GO:1900373	26	0.053
mitochondrion distribution	GO:0048311	4	0.053
ribose phosphate biosynthetic process	GO:0046390	59	0.053
optic nerve structural organization	GO:0021633	2	0.053
negative regulation of cellular component organization	GO:0051129	194	0.053
morphogenesis of embryonic epithelium	GO:0016331	159	0.053
transdifferentiation	GO:0060290	1	0.052
cell growth	GO:0016049	130	0.052
actin cytoskeleton organization	GO:0030036	220	0.052
divalent inorganic cation homeostasis	GO:0072507	138	0.052
cellular calcium ion homeostasis	GO:0006874	119	0.052
positive regulation of cell death	GO:0010942	224	0.052
cyclic nucleotide metabolic process	GO:0009187	59	0.052
positive regulation of protein kinase activity	GO:0045860	144	0.052
cell junction organization	GO:0034330	77	0.051
gonad development	GO:0008406	141	0.051
negative regulation of cellular protein metabolic process	GO:0032269	247	0.051
regulation of rac protein signal transduction	GO:0035020	19	0.051
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.051
response to monosaccharide	GO:0034284	67	0.051
regulation of long term synaptic depression	GO:1900452	3	0.051
neurotransmitter secretion	GO:0007269	62	0.051
regulation of muscle system process	GO:0090257	80	0.051
organelle localization	GO:0051640	179	0.051
heterocycle catabolic process	GO:0046700	280	0.051
nucleoside triphosphate metabolic process	GO:0009141	230	0.050
anatomical structure homeostasis	GO:0060249	145	0.050
defecation	GO:0030421	1	0.050
regulation of peptide transport	GO:0090087	91	0.050
notochord cell development	GO:0060035	1	0.050
response to amine	GO:0014075	16	0.050
negative regulation of behavior	GO:0048521	14	0.050
positive regulation of camp biosynthetic process	GO:0030819	19	0.049
positive regulation of synaptic transmission glutamatergic	GO:0051968	8	0.049
energy derivation by oxidation of organic compounds	GO:0015980	77	0.049
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	37	0.049
positive regulation of mapk cascade	GO:0043410	170	0.049
carboxylic acid transport	GO:0046942	100	0.049
regulation of ossification	GO:0030278	112	0.049
response to alkaloid	GO:0043279	34	0.048
establishment of blood nerve barrier	GO:0008065	3	0.048
multi organism behavior	GO:0051705	62	0.048
feeding behavior	GO:0007631	62	0.048
renal system development	GO:0072001	225	0.048
organonitrogen compound catabolic process	GO:1901565	264	0.048
dendritic spine organization	GO:0097061	26	0.047
pancreas development	GO:0031016	57	0.047
glycosyl compound catabolic process	GO:1901658	206	0.047
positive regulation of cyclic nucleotide metabolic process	GO:0030801	24	0.047
long term synaptic depression	GO:0060292	13	0.047
histamine induced gastric acid secretion	GO:0001697	1	0.047
photoreceptor cell development	GO:0042461	40	0.047
sa node cell action potential	GO:0086015	4	0.047
regulation of transferase activity	GO:0051338	263	0.047
cellular response to growth factor stimulus	GO:0071363	197	0.046
neural crest cell development	GO:0014032	48	0.046
establishment of glial blood brain barrier	GO:0060857	2	0.046
hexose metabolic process	GO:0019318	98	0.046
amino acid transmembrane transport	GO:0003333	37	0.045
cellular glucose homeostasis	GO:0001678	52	0.045
regulation of ras gtpase activity	GO:0032318	88	0.045
negative regulation of organelle organization	GO:0010639	90	0.045
fat cell differentiation	GO:0045444	160	0.045
cardiac chamber development	GO:0003205	108	0.045
acid secretion	GO:0046717	33	0.044
circulatory system process	GO:0003013	197	0.044
potassium ion transport	GO:0006813	52	0.044
nucleoside phosphate catabolic process	GO:1901292	222	0.044
positive regulation of the force of heart contraction by chemical signal	GO:0003099	3	0.044
regulation of actin cytoskeleton organization	GO:0032956	84	0.044
epithelial cell proliferation	GO:0050673	174	0.044
neuromuscular process controlling posture	GO:0050884	14	0.044	Mouse
positive regulation of vesicle fusion	GO:0031340	2	0.043
phototransduction	GO:0007602	17	0.043
positive regulation of dendrite development	GO:1900006	21	0.043
negative chemotaxis	GO:0050919	14	0.043
respiratory tube development	GO:0030323	167	0.043
renal sodium ion transport	GO:0003096	2	0.043
regulation of serotonin secretion	GO:0014062	3	0.043
calcium mediated signaling using intracellular calcium source	GO:0035584	3	0.043
morphogenesis of a branching structure	GO:0001763	203	0.043
photoreceptor cell differentiation	GO:0046530	52	0.042
digestive tract development	GO:0048565	190	0.042
regulation of apoptotic signaling pathway	GO:2001233	197	0.042
organophosphate biosynthetic process	GO:0090407	122	0.042
chromatin modification	GO:0016568	187	0.042
positive regulation of excitatory postsynaptic membrane potential	GO:2000463	14	0.042
epidermis development	GO:0008544	187	0.042
activation of meiosis involved in egg activation	GO:0060466	2	0.042
nucleoside triphosphate catabolic process	GO:0009143	205	0.042
regulation of adenylate cyclase activity	GO:0045761	10	0.042
positive regulation of glycolytic process	GO:0045821	4	0.041
membrane hyperpolarization	GO:0060081	21	0.041	Mouse
regulation of inward rectifier potassium channel activity	GO:1901979	1	0.041
tissue homeostasis	GO:0001894	115	0.041
regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0061178	31	0.041
conditioned taste aversion	GO:0001661	4	0.041
ribonucleotide catabolic process	GO:0009261	208	0.041
regulation of metal ion transport	GO:0010959	106	0.040
monocarboxylic acid metabolic process	GO:0032787	191	0.040
divalent metal ion transport	GO:0070838	172	0.040
regulation of ion transmembrane transporter activity	GO:0032412	54	0.040
protein localization to synapse	GO:0035418	11	0.040
regulation of anatomical structure size	GO:0090066	178	0.040
adenylate cyclase inhibiting g protein coupled receptor signaling pathway	GO:0007193	20	0.040
negative regulation of neuron projection regeneration	GO:0070571	3	0.040
regulation of ras protein signal transduction	GO:0046578	114	0.040
purine nucleoside catabolic process	GO:0006152	205	0.040
regulation of neurotransmitter secretion	GO:0046928	29	0.040
extracellular matrix organization	GO:0030198	147	0.039
regulation of heart rate	GO:0002027	36	0.039
positive regulation of adenylate cyclase activity	GO:0045762	8	0.039
sensitization	GO:0046960	2	0.039
glucose metabolic process	GO:0006006	92	0.039
regulation of camp biosynthetic process	GO:0030817	25	0.039
cellular nitrogen compound catabolic process	GO:0044270	280	0.039
acetylcholine transport	GO:0015870	2	0.039
cerebellum development	GO:0021549	77	0.039
organophosphate catabolic process	GO:0046434	232	0.039
g protein coupled acetylcholine receptor signaling pathway	GO:0007213	4	0.039
multi multicellular organism process	GO:0044706	109	0.038
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.038
positive regulation of synaptic plasticity	GO:0031915	4	0.038
stem cell maintenance	GO:0019827	130	0.038
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering	GO:0097113	3	0.038
monoamine transport	GO:0015844	33	0.038
postsynaptic membrane organization	GO:0001941	18	0.038
positive regulation of nucleotide biosynthetic process	GO:0030810	26	0.038
negative regulation of intracellular signal transduction	GO:1902532	167	0.037
multicellular organismal metabolic process	GO:0044236	28	0.037
negative regulation of synaptic transmission glutamatergic	GO:0051967	4	0.037
neural precursor cell proliferation	GO:0061351	121	0.037
operant conditioning	GO:0035106	2	0.036
ephrin receptor signaling pathway	GO:0048013	20	0.036
calcium ion transport	GO:0006816	159	0.036
ovulation	GO:0030728	15	0.036
directional locomotion	GO:0033058	3	0.036
diencephalon development	GO:0021536	63	0.036
ribonucleoside metabolic process	GO:0009119	245	0.036
metal ion homeostasis	GO:0055065	189	0.035
cardiac chamber morphogenesis	GO:0003206	93	0.035
neuropeptide signaling pathway	GO:0007218	19	0.035
regulation of purine nucleotide biosynthetic process	GO:1900371	34	0.035
positive regulation of gtpase activity	GO:0043547	85	0.035
cerebral cortex gabaergic interneuron differentiation	GO:0021892	9	0.035
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway	GO:0010579	3	0.035
multicellular organismal homeostasis	GO:0048871	164	0.035
negative regulation of growth	GO:0045926	99	0.035
substrate independent telencephalic tangential migration	GO:0021826	8	0.034
regulation of mapk cascade	GO:0043408	248	0.034
mating behavior	GO:0007617	20	0.034
telencephalon cell migration	GO:0022029	55	0.034
gastrulation	GO:0007369	116	0.034
response to amphetamine	GO:0001975	16	0.034
sensory perception of temperature stimulus	GO:0050951	9	0.034
osteoclast differentiation	GO:0030316	62	0.034
acetate ester transport	GO:1901374	2	0.034
muscle system process	GO:0003012	141	0.034
regulation of angiogenesis	GO:0045765	81	0.034
chloride transmembrane transport	GO:1902476	24	0.033	Mouse
aromatic compound catabolic process	GO:0019439	286	0.033
gastrin induced gastric acid secretion	GO:0001698	1	0.033
mesenchyme development	GO:0060485	152	0.033
negative regulation of cell development	GO:0010721	169	0.033
epithelial to mesenchymal transition	GO:0001837	47	0.033
branching morphogenesis of an epithelial tube	GO:0048754	159	0.033
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.033

Gabra2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
central nervous system disease	DOID:331	0.036
disease of anatomical entity	DOID:7	0.036
nervous system disease	DOID:863	0.036
musculoskeletal system disease	DOID:17	0.033

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