Mus musculus

15 known processes

Sp4

trans-acting transcription factor 4

(Aliases: HF-1b,HF1-b,5730497N03Rik)

Sp4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cilium morphogenesisGO:00602711020.172
gene silencingGO:0016458380.167
Fly
histone methylationGO:0016571710.158
methylationGO:00322591340.149
chromatin modificationGO:00165681870.133
chromatin silencingGO:0006342150.122
spermatogenesisGO:00072832840.120
histone modificationGO:00165701590.116
multicellular organism growthGO:00352641610.108
Mouse
covalent chromatin modificationGO:00165691630.106
cellular response to dna damage stimulusGO:00069742070.105
olfactory learningGO:000835520.101
male gamete generationGO:00482322850.097
macromolecule methylationGO:00434141200.092
protein alkylationGO:0008213810.091
positive regulation of growthGO:00459271040.084
t cell differentiationGO:00302171740.082
Mouse
dna metabolic processGO:00062593030.075
response to oxidative stressGO:00069791230.074
development of primary sexual characteristicsGO:00451371430.073
muscle tissue developmentGO:00605373080.073
myeloid cell differentiationGO:00300992330.068
Mouse
protein methylationGO:0006479810.068
negative regulation of protein metabolic processGO:00512482820.068
lymphocyte differentiationGO:00300982420.066
Mouse
chemotaxisGO:00069352470.065
chromatin organizationGO:00063252060.065
cellular amino acid metabolic processGO:00065201030.065
regulation of cellular amino acid metabolic processGO:000652150.063
striated muscle tissue developmentGO:00147062930.063
translationGO:0006412930.062
epithelial cell developmentGO:00020641590.062
axon guidanceGO:00074111410.061
regulation of translationGO:0006417710.059
negative regulation of molecular functionGO:00440922580.058
hindbrain developmentGO:00309021280.058
camera type eye developmentGO:00430102660.057
Mouse
skeletal muscle cell differentiationGO:0035914660.056
germ cell developmentGO:00072811850.055
ossificationGO:00015032160.054
Mouse
stem cell differentiationGO:00488632680.054
regulation of organelle organizationGO:00330432890.053
nuclear divisionGO:00002801580.052
posttranscriptional regulation of gene expressionGO:00106081550.052
t cell activationGO:00421102890.052
Mouse
leukocyte differentiationGO:00025213420.051
Mouse
regulation of chromosome organizationGO:0033044830.051
microtubule cytoskeleton organizationGO:00002261570.050
peptidyl amino acid modificationGO:00181933360.048
respiratory tube developmentGO:00303231670.048
Mouse
circadian rhythmGO:00076231140.048
protein ubiquitinationGO:00165671710.047
smoothened signaling pathwayGO:00072241050.047
embryonic organ morphogenesisGO:00485622760.047
Mouse
protein processingGO:00164851630.047
respiratory system developmentGO:00605411900.045
Mouse
regulation of cellular ketone metabolic processGO:0010565660.044
metencephalon developmentGO:0022037890.043
digestive system developmentGO:00551232000.042
histone lysine methylationGO:0034968500.041
regulation of secretionGO:00510462740.041
negative regulation of gene expression epigeneticGO:0045814150.041
t cell proliferationGO:00420981200.041
neuron projection guidanceGO:00974851410.040
rna interferenceGO:001624620.040
regulation of lymphocyte activationGO:00512492400.039
male sex differentiationGO:00466611090.037
cell maturationGO:00484691270.037
macromolecule catabolic processGO:00090572810.036
male gonad developmentGO:0008584880.036
histone lysine demethylationGO:0070076130.035
muscle cell differentiationGO:00426922610.035
alpha beta t cell activation involved in immune responseGO:0002287310.034
regulation of cell activationGO:00508652890.034
mrna metabolic processGO:0016071840.034
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.033
gland developmentGO:00487323300.033
Mouse
circulatory system processGO:00030131970.033
regulation of cell cycle processGO:00105641600.033
aromatic compound catabolic processGO:00194392860.033
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.033
regulation of cell cycleGO:00517262810.033
positive regulation of cellular amine metabolic processGO:003324050.033
regulation of cellular amine metabolic processGO:0033238200.031
alpha beta t cell activationGO:0046631910.031
stem cell maintenanceGO:00198271300.031
compound eye developmentGO:004874910.031
positive regulation of protein modification processGO:00314012990.030
negative regulation of cellular protein metabolic processGO:00322692470.030
rhythmic processGO:00485111740.030
microtubule based processGO:00070172360.030
positive regulation of cellular amino acid metabolic processGO:004576430.029
hepaticobiliary system developmentGO:0061008670.029
Mouse
regulation of cellular response to stressGO:00801351590.029
regulation of viral transcriptionGO:004678230.029
mapk cascadeGO:00001652810.029
spermatid developmentGO:00072861080.029
cellular response to lipidGO:00713961450.029
blood circulationGO:00080151950.029
female sex differentiationGO:0046660840.029
cellular response to lipopolysaccharideGO:0071222770.028
positive regulation of histone h3 k9 methylationGO:005157440.028
cardiac muscle tissue developmentGO:00487381300.028
histone h3 k9 methylationGO:0051567170.027
gonad developmentGO:00084061410.027
cellular ketone metabolic processGO:0042180840.027
regulation of apoptotic signaling pathwayGO:20012331970.027
heart morphogenesisGO:00030071780.027
segmentationGO:0035282930.027
axonogenesisGO:00074092740.026
central nervous system neuron differentiationGO:00219531620.026
organelle localizationGO:00516401790.026
appendage developmentGO:00487361660.026
Mouse
response to inorganic substanceGO:0010035960.026
appendage morphogenesisGO:00351071490.026
Mouse
regulation of kinase activityGO:00435492490.026
somitogenesisGO:0001756690.026
endothelial cell differentiationGO:0045446410.026
organelle assemblyGO:00709251770.025
histone h3 k9 trimethylationGO:003612460.025
cellular response to hormone stimulusGO:00328701500.025
purine nucleotide metabolic processGO:00061633020.025
placenta developmentGO:00018901400.025
Mouse
cell cycle checkpointGO:0000075470.025
hematopoietic progenitor cell differentiationGO:00022441430.024
Mouse
response to lipopolysaccharideGO:00324961280.024
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.024
negative regulation of lymphocyte activationGO:0051250910.024
neural tube developmentGO:00219151600.024
regulation of organ growthGO:0046620610.023
mrna processingGO:0006397630.023
cognitionGO:00508901490.023
protein maturationGO:00516041760.023
regulation of transferase activityGO:00513382630.023
negative regulation of nervous system developmentGO:00519611560.023
positive regulation of cell developmentGO:00107202370.023
ear morphogenesisGO:00424711180.023
regulation of vesicle mediated transportGO:00606271390.023
amine metabolic processGO:0009308450.022
telencephalon developmentGO:00215371860.022
forebrain developmentGO:00309003020.022
pharynx developmentGO:006046510.022
skin developmentGO:00435882200.022
positive regulation of cell activationGO:00508671580.022
regulation of chromatin silencingGO:003193520.022
regulation of protein serine threonine kinase activityGO:00719001570.021
nuclear transcribed mrna poly a tail shorteningGO:000028970.021
leukocyte proliferationGO:00706611720.021
response to insulinGO:00328681000.021
dna recombinationGO:0006310920.021
skeletal muscle organ developmentGO:00605381630.020
protein polymerizationGO:0051258570.020
cell type specific apoptotic processGO:00972852680.020
posttranscriptional gene silencingGO:0016441100.020
meiosis iGO:0007127600.020
regulation of protein maturationGO:1903317960.020
stem cell developmentGO:00488642190.020
learning or memoryGO:00076111480.020
cellular response to molecule of bacterial originGO:0071219830.020
negative regulation of cell proliferationGO:00082852960.020
cation transportGO:00068123990.020
regulation of secretion by cellGO:19035302490.020
negative regulation of protein maturationGO:1903318790.020
syncytium formation by plasma membrane fusionGO:0000768420.020
negative regulation of cellular component organizationGO:00511291940.020
primary neural tube formationGO:0014020950.020
developmental maturationGO:00217001930.020
peptidyl lysine methylationGO:0018022290.019
spermatid differentiationGO:00485151150.019
lymphocyte proliferationGO:00466511640.019
regulation of cellular catabolic processGO:00313292420.019
rna processingGO:00063961050.019
organ growthGO:00352651170.019
response to peptide hormoneGO:00434341270.019
leukocyte activation involved in immune responseGO:00023661260.019
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.019
negative regulation of synapse assemblyGO:005196430.019
epithelial tube morphogenesisGO:00605623030.019
immune effector processGO:00022523210.019
positive regulation of organelle organizationGO:00106381280.019
development of primary male sexual characteristicsGO:0046546880.019
positive regulation of nervous system developmentGO:00519622210.019
digestive tract morphogenesisGO:00485461470.019
nitrogen compound transportGO:00717052710.019
b cell activationGO:00421131610.019
Mouse
regulation of leukocyte differentiationGO:19021051590.019
urogenital system developmentGO:00016552610.018
cellularizationGO:000734910.018
alpha beta t cell differentiationGO:0046632690.018
cellular macromolecule catabolic processGO:00442652060.018
antigen receptor mediated signaling pathwayGO:0050851640.018
positive regulation of dna templated transcription elongationGO:003278620.018
regulation of histone methylationGO:0031060300.018
sensory perception of soundGO:0007605970.018
inorganic ion transmembrane transportGO:00986602340.018
retina development in camera type eyeGO:00600411190.018
organelle fissionGO:00482851700.018
heterocycle catabolic processGO:00467002800.017
regulation of multi organism processGO:00439001110.017
circadian behaviorGO:0048512130.017
renal system developmentGO:00720012250.017
cellular response to abiotic stimulusGO:0071214560.017
cell activation involved in immune responseGO:00022631260.017
mesenchyme developmentGO:00604851520.017
regulation of chromatin modificationGO:1903308570.017
regulation of histone h3 k9 methylationGO:005157080.017
embryonic placenta developmentGO:0001892980.017
Mouse
regulation of cellular component biogenesisGO:00440871810.017
regulation of voltage gated calcium channel activityGO:190138540.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
canonical wnt signaling pathwayGO:00600701300.017
embryonic skeletal system developmentGO:00487061200.017
Mouse
regulation of lymphocyte differentiationGO:00456191070.017
regulation of mapk cascadeGO:00434082480.017
rna catabolic processGO:0006401290.017
regulation of hormone levelsGO:00108172110.017
positive regulation of protein phosphorylationGO:00019342420.017
negative regulation of cell cycle phase transitionGO:1901988480.017
sensory perception of mechanical stimulusGO:00509541070.016
negative regulation of organelle organizationGO:0010639900.016
synaptic transmissionGO:00072683290.016
cell divisionGO:00513011200.016
positive regulation of histone methylationGO:0031062160.016
mitotic cell cycleGO:00002781950.016
negative regulation of phosphorylationGO:00423261660.016
maintenance of locationGO:0051235890.016
organonitrogen compound catabolic processGO:19015652640.016
cardiac muscle cell differentiationGO:0055007690.016
histone h4 k20 methylationGO:003477080.015
cellular response to steroid hormone stimulusGO:0071383330.015
glycosyl compound metabolic processGO:19016572460.015
cytoplasmic transportGO:00164822340.015
lung developmentGO:00303241640.015
Mouse
cellular amine metabolic processGO:0044106440.015
regulation of bindingGO:00510981110.015
response to acid chemicalGO:00011011110.015
blood vessel morphogenesisGO:00485142850.015
lymphocyte mediated immunityGO:00024491390.015
pole plasm assemblyGO:000731520.015
cellular response to organic cyclic compoundGO:0071407870.015
genitalia developmentGO:0048806370.015
negative regulation of cell cycleGO:00457861230.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
response to light stimulusGO:00094161350.015
regulation of histone modificationGO:0031056560.015
leukocyte mediated immunityGO:00024431740.015
oxidation reduction processGO:00551143420.015
negative regulation of protein processingGO:0010955790.015
cation transmembrane transportGO:00986552660.015
response to organonitrogen compoundGO:00102432460.015
morphogenesis of embryonic epitheliumGO:00163311590.015
inorganic cation transmembrane transportGO:00986622070.015
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288120.015
response to peptideGO:19016521360.014
columnar cuboidal epithelial cell differentiationGO:0002065820.014
negative regulation of protein modification processGO:00314001630.014
response to organic cyclic compoundGO:00140701980.014
mitotic cell cycle processGO:19030471590.014
cd4 positive alpha beta t cell activationGO:0035710450.014
regulation of protein processingGO:0070613960.014
habituationGO:004695930.014
response to molecule of bacterial originGO:00022371430.014
cellular homeostasisGO:00197252400.014
multi organism behaviorGO:0051705620.014
macromolecule deacylationGO:0098732370.014
cd4 positive alpha beta t cell differentiationGO:0043367410.014
regulation of neuron projection developmentGO:00109751690.014
ribonucleoprotein complex subunit organizationGO:0071826280.014
protein deacetylationGO:0006476320.014
ribose phosphate metabolic processGO:00196932910.014
cytoplasmic mrna processing body assemblyGO:003396260.014
cellular protein catabolic processGO:00442571550.014
organophosphate biosynthetic processGO:00904071220.014
ear developmentGO:00435832000.014
amide transportGO:00428861380.014
sensory perceptionGO:00076002450.014
cellular response to peptide hormone stimulusGO:0071375920.014
viral gene expressionGO:001908030.014
nucleoside triphosphate metabolic processGO:00091412300.014
negative regulation of translationGO:0017148220.014
transdifferentiationGO:006029010.013
regulation of leukocyte proliferationGO:00706631210.013
nucleobase containing small molecule metabolic processGO:00550863520.013
regulation of adaptive immune responseGO:0002819900.013
carbohydrate metabolic processGO:00059752300.013
embryonic appendage morphogenesisGO:00351131260.013
Mouse
regulation of b cell activationGO:0050864810.013
positive regulation of chromosome organizationGO:2001252330.013
gene silencing by rnaGO:0031047190.013
negative regulation of protein phosphorylationGO:00019331260.013
cellular response to peptideGO:1901653920.013
carbohydrate homeostasisGO:00335001280.013
cellular nitrogen compound catabolic processGO:00442702800.013
neural precursor cell proliferationGO:00613511210.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
viral transcriptionGO:001908330.013
chromatin assembly or disassemblyGO:0006333160.013
activation of immune responseGO:00022531380.013
endocytosisGO:00068971680.013
myeloid leukocyte differentiationGO:00025731190.013
Mouse
transmembrane transportGO:00550854120.013
cellular response to oxidative stressGO:0034599760.013
immune response activating signal transductionGO:00027571160.013
ventricular cardiac myofibril assemblyGO:005500530.013
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.013
limb developmentGO:00601731660.013
Mouse
histone deacetylationGO:0016575260.013
regulation of t cell activationGO:00508631700.013
organic cyclic compound catabolic processGO:19013612950.013
actin cytoskeleton organizationGO:00300362200.012
thymus developmentGO:0048538410.012
digestive tract developmentGO:00485651900.012
regulation of neuron differentiationGO:00456642810.012
regulation of establishment of protein localizationGO:00702011810.012
cerebellum morphogenesisGO:0021587420.012
connective tissue developmentGO:00614481790.012
cellular component assembly involved in morphogenesisGO:00109271390.012
endothelium developmentGO:0003158450.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
regulation of epithelial cell proliferationGO:00506781410.012
divalent inorganic cation homeostasisGO:00725071380.012
lipid localizationGO:00108761260.012
response to radiationGO:00093141650.012
adaptive immune responseGO:00022501550.012
positive regulation of cell cycleGO:0045787920.012
sensory organ morphogenesisGO:00905962420.012
Mouse
nucleoside catabolic processGO:00091642060.012
epithelial cell proliferationGO:00506731740.012
histone demethylationGO:0016577130.012
nucleotide metabolic processGO:00091173320.012
bmp signaling pathwayGO:0030509930.012
immune response regulating cell surface receptor signaling pathwayGO:0002768800.012
positive regulation of homeostatic processGO:0032846640.012
ectoderm formationGO:000170530.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.012
regulation of cell cycle phase transitionGO:1901987770.012
vagus nerve developmentGO:002156430.012
positive regulation of programmed cell deathGO:00430682180.012
rna splicing via transesterification reactionsGO:0000375430.012
t cell activation involved in immune responseGO:0002286430.012
cardiocyte differentiationGO:0035051870.012
regulation of sequence specific dna binding transcription factor activityGO:00510901060.012
nucleocytoplasmic transportGO:00069131390.012
establishment or maintenance of cytoskeleton polarityGO:003095220.012
regulation of lymphocyte proliferationGO:00506701170.012
sensory system developmentGO:004888030.012
protein dealkylationGO:0008214130.012
angiogenesisGO:00015252010.012
somite developmentGO:0061053810.012
negative regulation of t helper 2 cell differentiationGO:004562940.012
mesenchymal cell differentiationGO:00487621070.011
protein modification by small protein conjugation or removalGO:00706472070.011
oocyte constructionGO:000730820.011
negative regulation of proteolysisGO:0045861740.011
cellular metal ion homeostasisGO:00068751510.011
cellular response to organonitrogen compoundGO:00714171450.011
cell differentiation in spinal cordGO:0021515530.011
regulation of defense responseGO:00313472330.011
negative regulation of cell cycle processGO:0010948690.011
negative regulation of mesenchymal cell proliferationGO:007220130.011
regulation of protein complex assemblyGO:0043254830.011
ribonucleoside metabolic processGO:00091192450.011
cerebellum developmentGO:0021549770.011
telomere maintenanceGO:0000723190.011
regulation of cell motilityGO:20001452360.011
ovarian follicle developmentGO:0001541400.011
peptide hormone secretionGO:00300721090.011
positive regulation of apoptotic processGO:00430652170.011
myeloid cell homeostasisGO:00022621140.011
Mouse
positive regulation of stem cell proliferationGO:2000648590.011
purine ribonucleotide catabolic processGO:00091542080.011
positive regulation of transferase activityGO:00513471670.011
regulation of protein bindingGO:0043393600.011
dna methylationGO:0006306430.011
regulation of cell divisionGO:0051302760.011
protein demethylationGO:0006482130.011
wound healingGO:00420601570.011
g1 s transition of mitotic cell cycleGO:0000082570.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
posttranscriptional gene silencing by rnaGO:0035194100.011
negative regulation of t cell activationGO:0050868650.011
oocyte axis specificationGO:000730920.011
limb morphogenesisGO:00351081490.011
Mouse
pancreas developmentGO:0031016570.011
meiotic nuclear divisionGO:00071261150.011
palate developmentGO:0060021760.011
protein localization to organelleGO:00333651850.011
peptidyl lysine modificationGO:0018205770.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
negative regulation of phosphate metabolic processGO:00459361840.011
inner ear morphogenesisGO:00424721010.010
chromatin remodelingGO:0006338320.010
locomotory behaviorGO:00076261950.010
regulation of muscle tissue developmentGO:1901861970.010
negative regulation of cell activationGO:00508661110.010
histone h3 k4 methylationGO:0051568230.010
organic hydroxy compound metabolic processGO:19016152030.010
regulation of transcription by chromatin organizationGO:003440100.010
wnt signaling pathwayGO:00160551880.010
male courtship behaviorGO:000804920.010
cellular chemical homeostasisGO:00550822150.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
negative regulation of chromosome organizationGO:2001251300.010
regulation of stem cell proliferationGO:0072091780.010
regulation of circadian rhythmGO:0042752580.010
intracellular receptor signaling pathwayGO:0030522740.010
labyrinthine layer developmentGO:0060711490.010
female gamete generationGO:0007292740.010
his purkinje system cell differentiationGO:006093220.010
cellular response to external stimulusGO:0071496880.010
protein modification by small protein conjugationGO:00324461870.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
rna 3 end processingGO:0031123200.010
neuron migrationGO:00017641220.010

Sp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015
nervous system diseaseDOID:86300.015
central nervous system diseaseDOID:33100.011