Mus musculus

74 known processes

Spr

sepiapterin reductase

(Aliases: Gm10328,ENSMUSG00000071345,AA409688)

Spr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.148
purine nucleotide metabolic processGO:00061633020.097
small molecule catabolic processGO:0044282710.092
ribose phosphate metabolic processGO:00196932910.082
cellular lipid metabolic processGO:00442553230.082
purine ribonucleotide metabolic processGO:00091502900.081
purine ribonucleoside triphosphate metabolic processGO:00092052200.071
nucleotide metabolic processGO:00091173320.067
cellular amino acid metabolic processGO:00065201030.059
purine nucleoside triphosphate metabolic processGO:00091442260.056
organonitrogen compound catabolic processGO:19015652640.056
purine ribonucleoside metabolic processGO:00461282410.055
mitochondrion organizationGO:00070051340.052
intracellular protein transportGO:00068862040.051
purine containing compound metabolic processGO:00725213110.046
heterocycle catabolic processGO:00467002800.044
membrane organizationGO:00610242450.044
regulation of cellular amino acid metabolic processGO:000652150.043
nucleoside triphosphate metabolic processGO:00091412300.043
glycosyl compound metabolic processGO:19016572460.043
ribonucleotide metabolic processGO:00092592910.041
nucleobase containing small molecule metabolic processGO:00550863520.040
regulation of cellular ketone metabolic processGO:0010565660.038
purine ribonucleoside catabolic processGO:00461302050.038
ribonucleoside metabolic processGO:00091192450.037
amine metabolic processGO:0009308450.037
ribonucleotide catabolic processGO:00092612080.036
transmembrane transportGO:00550854120.036
atp metabolic processGO:0046034750.035
nucleoside phosphate metabolic processGO:00067533380.035
cellular ketone metabolic processGO:0042180840.035
regulation of cellular amine metabolic processGO:0033238200.035
purine nucleotide catabolic processGO:00061952110.034
cation transportGO:00068123990.034
t cell activationGO:00421102890.034
regulation of organelle organizationGO:00330432890.034
carboxylic acid catabolic processGO:0046395510.034
ribonucleoside triphosphate metabolic processGO:00091992200.033
protein localization to organelleGO:00333651850.032
regulation of purine nucleotide metabolic processGO:19005421690.032
nitrogen compound transportGO:00717052710.032
ribonucleoside catabolic processGO:00424542060.032
nucleotide catabolic processGO:00091662170.030
protein targetingGO:00066051430.030
cellular amine metabolic processGO:0044106440.030
aromatic compound catabolic processGO:00194392860.030
regulation of hormone levelsGO:00108172110.029
nucleoside triphosphate catabolic processGO:00091432050.029
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
dna metabolic processGO:00062593030.029
purine ribonucleoside monophosphate metabolic processGO:0009167800.028
ribonucleoside triphosphate catabolic processGO:00092031990.028
response to organic cyclic compoundGO:00140701980.028
organophosphate catabolic processGO:00464342320.028
cellular nitrogen compound catabolic processGO:00442702800.028
amide transportGO:00428861380.028
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.027
nucleoside metabolic processGO:00091162460.027
regulation of neuron differentiationGO:00456642810.027
germ cell developmentGO:00072811850.027
organonitrogen compound biosynthetic processGO:19015661920.026
regulation of membrane potentialGO:00423911920.026
response to oxidative stressGO:00069791230.026
monocarboxylic acid metabolic processGO:00327871910.025
carbohydrate derivative biosynthetic processGO:19011371830.025
skeletal system developmentGO:00015013560.025
negative regulation of molecular functionGO:00440922580.025
regulation of cell activationGO:00508652890.025
cellular lipid catabolic processGO:0044242520.025
nucleoside phosphate catabolic processGO:19012922220.025
ion transmembrane transportGO:00342203610.024
defecationGO:003042110.024
cellular homeostasisGO:00197252400.024
peptidyl amino acid modificationGO:00181933360.024
endomembrane system organizationGO:00102561470.024
purine nucleoside metabolic processGO:00422782410.024
regulation of lymphocyte activationGO:00512492400.023
transmission of nerve impulseGO:0019226760.023
organic hydroxy compound metabolic processGO:19016152030.023
guanosine containing compound catabolic processGO:19010691440.023
epithelial tube morphogenesisGO:00605623030.023
male gamete generationGO:00482322850.023
cytoplasmic transportGO:00164822340.023
response to inorganic substanceGO:0010035960.023
organic acid catabolic processGO:0016054510.023
dephosphorylationGO:00163111290.022
negative regulation of cellular protein metabolic processGO:00322692470.022
carbohydrate derivative catabolic processGO:19011362310.022
cytokine productionGO:00018163190.022
organic cyclic compound catabolic processGO:19013612950.022
regulation of protein localizationGO:00328802310.022
alcohol metabolic processGO:00060661160.021
regulation of ion transportGO:00432692150.021
response to decreased oxygen levelsGO:0036293590.021
macromolecule catabolic processGO:00090572810.021
carbohydrate homeostasisGO:00335001280.021
regulation of feeding behaviorGO:006025930.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
blood vessel morphogenesisGO:00485142850.020
positive regulation of cellular amine metabolic processGO:003324050.020
gland developmentGO:00487323300.020
establishment of protein localization to organelleGO:00725941180.020
cell adhesionGO:00071553290.020
digestive system developmentGO:00551232000.020
cation transmembrane transportGO:00986552660.020
action potentialGO:0001508780.020
spermatogenesisGO:00072832840.019
regulation of secretion by cellGO:19035302490.019
inorganic ion transmembrane transportGO:00986602340.019
multicellular organismal signalingGO:0035637910.019
leukocyte differentiationGO:00025213420.019
regulation of hydrolase activityGO:00513362460.019
purine nucleoside catabolic processGO:00061522050.019
vesicle localizationGO:0051648860.019
gtp catabolic processGO:00061841430.018
regulation of nucleotide metabolic processGO:00061401690.018
purine nucleoside triphosphate catabolic processGO:00091462030.018
anatomical structure homeostasisGO:00602491450.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
purine ribonucleotide catabolic processGO:00091542080.018
carbohydrate metabolic processGO:00059752300.018
gliogenesisGO:00420631410.018
cation homeostasisGO:00550802120.018
synaptic transmissionGO:00072683290.017
cellular ion homeostasisGO:00068731650.017
positive regulation of protein modification processGO:00314012990.017
regulation of cytokine productionGO:00018172660.017
myeloid cell differentiationGO:00300992330.017
cellular response to lipidGO:00713961450.017
positive regulation of programmed cell deathGO:00430682180.017
protein localization to mitochondrionGO:0070585150.017
myeloid leukocyte differentiationGO:00025731190.017
cellular carbohydrate metabolic processGO:00442621190.017
regulation of secretionGO:00510462740.017
purine containing compound catabolic processGO:00725232130.017
positive regulation of apoptotic processGO:00430652170.017
gtp metabolic processGO:00460391440.017
compound eye developmentGO:004874910.017
steroid metabolic processGO:00082021190.017
glucose metabolic processGO:0006006920.016
generation of precursor metabolites and energyGO:00060911030.016
protein oligomerizationGO:0051259670.016
divalent inorganic cation homeostasisGO:00725071380.016
inflammatory responseGO:00069542440.016
protein modification by small protein conjugationGO:00324461870.016
regulation of cellular catabolic processGO:00313292420.016
nucleoside monophosphate metabolic processGO:0009123850.016
neuronal action potentialGO:0019228540.016
neural tube developmentGO:00219151600.016
ribonucleoside monophosphate metabolic processGO:0009161800.016
lateral inhibitionGO:004633110.016
purine nucleoside monophosphate metabolic processGO:0009126810.016
respiratory tube developmentGO:00303231670.016
endocytosisGO:00068971680.015
regulation of lymphocyte proliferationGO:00506701170.015
neuron deathGO:00709971540.015
negative regulation of protein metabolic processGO:00512482820.015
sensory perceptionGO:00076002450.015
cellular chemical homeostasisGO:00550822150.015
peptide hormone secretionGO:00300721090.015
sensory organ morphogenesisGO:00905962420.015
ribose phosphate biosynthetic processGO:0046390590.015
succinate transportGO:001574410.015
rho protein signal transductionGO:0007266320.015
cofactor biosynthetic processGO:0051188410.015
positive regulation of organelle organizationGO:00106381280.015
positive regulation of cell deathGO:00109422240.015
plasma membrane organizationGO:0007009900.015
regulation of protein transportGO:00512231630.015
glucose homeostasisGO:00425931280.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
sulfur compound metabolic processGO:00067901000.015
peptide secretionGO:00027901140.015
response to radiationGO:00093141650.015
regulation of cellular component sizeGO:00325351210.015
regulation of t cell activationGO:00508631700.015
muscle system processGO:00030121410.015
posttranscriptional regulation of gene expressionGO:00106081550.014
muscle cell differentiationGO:00426922610.014
mapk cascadeGO:00001652810.014
regulation of response to woundingGO:19030341890.014
glycosyl compound catabolic processGO:19016582060.014
lipid biosynthetic processGO:00086101790.014
cellular protein complex assemblyGO:00436231160.014
regulation of cell motilityGO:20001452360.014
renal system developmentGO:00720012250.014
regulation of lipid metabolic processGO:00192161180.014
single organism nuclear importGO:1902593950.014
negative regulation of cellular amine metabolic processGO:003323910.014
response to oxygen levelsGO:0070482620.014
multi multicellular organism processGO:00447061090.014
morphogenesis of embryonic epitheliumGO:00163311590.014
peptidyl tyrosine modificationGO:00182121450.014
response to hypoxiaGO:0001666580.014
liver developmentGO:0001889660.014
regulation of cell projection organizationGO:00313442060.013
tissue homeostasisGO:00018941150.013
guanosine containing compound metabolic processGO:19010681440.013
cell type specific apoptotic processGO:00972852680.013
urogenital system developmentGO:00016552610.013
response to organonitrogen compoundGO:00102432460.013
immune effector processGO:00022523210.013
organelle assemblyGO:00709251770.013
rhythmic processGO:00485111740.013
positive regulation of cell activationGO:00508671580.013
regulation of mapk cascadeGO:00434082480.013
regulation of establishment of protein localizationGO:00702011810.013
small gtpase mediated signal transductionGO:0007264970.013
response to starvationGO:0042594650.013
cellular metal ion homeostasisGO:00068751510.013
regulation of leukocyte proliferationGO:00706631210.013
lymphocyte differentiationGO:00300982420.013
homeostasis of number of cellsGO:00488722100.013
organelle localizationGO:00516401790.013
negative regulation of phosphorus metabolic processGO:00105631840.013
connective tissue developmentGO:00614481790.013
adult behaviorGO:00305341350.013
protein importGO:00170381010.013
positive regulation of protein phosphorylationGO:00019342420.013
regulation of lymphocyte differentiationGO:00456191070.013
glycerolipid metabolic processGO:00464861220.013
divalent metal ion transportGO:00708381720.013
organophosphate biosynthetic processGO:00904071220.013
nucleoside catabolic processGO:00091642060.013
negative regulation of protein modification processGO:00314001630.013
insulin secretionGO:0030073890.013
calcium ion homeostasisGO:00550741270.012
negative regulation of neuron deathGO:1901215980.012
glycoprotein biosynthetic processGO:0009101890.012
embryonic organ morphogenesisGO:00485622760.012
reactive oxygen species metabolic processGO:0072593840.012
peptide transportGO:00158331330.012
regulation of nucleoside metabolic processGO:00091181300.012
pteridine containing compound metabolic processGO:004255850.012
protein ubiquitinationGO:00165671710.012
cellular response to external stimulusGO:0071496880.012
regulation of leukocyte differentiationGO:19021051590.012
respiratory system developmentGO:00605411900.012
nucleocytoplasmic transportGO:00069131390.012
regulation of neuron deathGO:19012141340.012
lymphocyte proliferationGO:00466511640.012
positive regulation of nervous system developmentGO:00519622210.012
carboxylic acid transportGO:00469421000.012
protein catabolic processGO:00301632210.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
leukocyte mediated immunityGO:00024431740.012
histone modificationGO:00165701590.012
modification dependent protein catabolic processGO:00199411330.012
positive regulation of lymphocyte activationGO:00512511400.012
peptidyl tyrosine phosphorylationGO:00181081430.012
negative regulation of phosphorylationGO:00423261660.012
energy derivation by oxidation of organic compoundsGO:0015980770.012
regulation of actin filament based processGO:0032970990.012
regulation of neuron projection developmentGO:00109751690.012
i kappab kinase nf kappab signalingGO:0007249850.012
response to acid chemicalGO:00011011110.012
single organism cell adhesionGO:00986021560.012
metal ion homeostasisGO:00550651890.012
locomotory behaviorGO:00076261950.011
protein localization to nucleusGO:00345041210.011
negative regulation of phosphate metabolic processGO:00459361840.011
establishment of vesicle localizationGO:0051650810.011
positive regulation of growthGO:00459271040.011
cellular response to extracellular stimulusGO:0031668810.011
ensheathment of neuronsGO:0007272760.011
b cell activationGO:00421131610.011
maintenance of locationGO:0051235890.011
positive regulation of secretionGO:00510471300.011
protein maturationGO:00516041760.011
ubiquitin dependent protein catabolic processGO:00065111290.011
leukocyte proliferationGO:00706611720.011
negative regulation of cell proliferationGO:00082852960.011
chromatin organizationGO:00063252060.011
actin cytoskeleton organizationGO:00300362200.011
mitochondrial membrane organizationGO:0007006260.011
divalent inorganic cation transportGO:00725111780.011
development of primary sexual characteristicsGO:00451371430.011
lung developmentGO:00303241640.011
angiogenesisGO:00015252010.011
forebrain developmentGO:00309003020.011
learning or memoryGO:00076111480.011
circulatory system processGO:00030131970.011
positive regulation of transferase activityGO:00513471670.011
inorganic cation transmembrane transportGO:00986622070.011
protein localization to membraneGO:00726571080.011
negative regulation of cellular component organizationGO:00511291940.011
response to extracellular stimulusGO:00099911270.011
sequestering of metal ionGO:0051238190.010
establishment of protein localization to membraneGO:0090150540.010
cofactor metabolic processGO:0051186800.010
cardiac chamber developmentGO:00032051080.010
monosaccharide metabolic processGO:00059961060.010
reactive nitrogen species metabolic processGO:200105700.010
telencephalon developmentGO:00215371860.010
protein modification by small protein conjugation or removalGO:00706472070.010
response to nutrient levelsGO:00316671090.010
lipid modificationGO:0030258650.010
regulation of proteolysisGO:00301621640.010
regulation of homeostatic processGO:00328441820.010
cellular respirationGO:0045333380.010
calcium ion transportGO:00068161590.010
cellular response to acid chemicalGO:0071229680.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
positive regulation of mapk cascadeGO:00434101700.010
covalent chromatin modificationGO:00165691630.010
response to drugGO:0042493750.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
lipid localizationGO:00108761260.010
positive regulation of secretion by cellGO:19035321140.010
negative regulation of protein phosphorylationGO:00019331260.010

Spr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
organ system cancerDOID:005068600.021
central nervous system diseaseDOID:33100.011
disease of anatomical entityDOID:700.011
nervous system diseaseDOID:86300.011
gastrointestinal system cancerDOID:311900.011