Mus musculus

40 known processes

Akr1c18

aldo-keto reductase family 1, member C18

(Aliases: AW146047)

Akr1c18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.248
Human
cation transportGO:00068123990.119
transmembrane transportGO:00550854120.105
cellular ketone metabolic processGO:0042180840.103
ion transmembrane transportGO:00342203610.092
anion transportGO:00068201770.089
amine metabolic processGO:0009308450.080
lipid biosynthetic processGO:00086101790.077
Rat
organic hydroxy compound metabolic processGO:19016152030.071
Human
cellular amine metabolic processGO:0044106440.070
regulation of cellular amine metabolic processGO:0033238200.068
regulation of hormone levelsGO:00108172110.067
regulation of cellular ketone metabolic processGO:0010565660.066
oxidation reduction processGO:00551143420.063
regulation of ion transportGO:00432692150.059
fatty acid metabolic processGO:00066311210.057
Human
calcium ion transportGO:00068161590.055
response to organonitrogen compoundGO:00102432460.054
regulation of cellular amino acid metabolic processGO:000652150.053
myeloid cell differentiationGO:00300992330.052
steroid metabolic processGO:00082021190.052
cellular amino acid metabolic processGO:00065201030.051
blood circulationGO:00080151950.051
regulation of body fluid levelsGO:00508781620.049
positive regulation of cellular amino acid metabolic processGO:004576430.049
t cell activationGO:00421102890.048
aromatic compound catabolic processGO:00194392860.046
positive regulation of secretionGO:00510471300.046
response to organic cyclic compoundGO:00140701980.045
positive regulation of cellular amine metabolic processGO:003324050.045
immune effector processGO:00022523210.043
epidermis developmentGO:00085441870.043
skin developmentGO:00435882200.042
organic cyclic compound catabolic processGO:19013612950.042
nucleobase containing small molecule metabolic processGO:00550863520.040
sensory perceptionGO:00076002450.040
cellular homeostasisGO:00197252400.040
g protein coupled receptor signaling pathwayGO:00071862430.040
Human
regulation of secretion by cellGO:19035302490.040
urogenital system developmentGO:00016552610.040
response to light stimulusGO:00094161350.040
divalent metal ion transportGO:00708381720.040
regulation of lipid metabolic processGO:00192161180.040
Rat
nucleotide metabolic processGO:00091173320.039
regulation of vesicle mediated transportGO:00606271390.039
negative regulation of immune system processGO:00026832090.038
inflammatory responseGO:00069542440.038
regulation of cell migrationGO:00303342190.038
cation transmembrane transportGO:00986552660.038
membrane organizationGO:00610242450.037
regulation of metal ion transportGO:00109591060.036
regulation of cytokine productionGO:00018172660.036
positive regulation of secretion by cellGO:19035321140.036
leukocyte differentiationGO:00025213420.034
multicellular organismal signalingGO:0035637910.033
cellular chemical homeostasisGO:00550822150.033
macromolecule catabolic processGO:00090572810.033
cellular nitrogen compound catabolic processGO:00442702800.033
inorganic ion transmembrane transportGO:00986602340.033
alcohol metabolic processGO:00060661160.033
regulation of protein transportGO:00512231630.032
regulation of cell activationGO:00508652890.032
regulation of response to woundingGO:19030341890.032
mapk cascadeGO:00001652810.032
kidney developmentGO:00018222130.032
nucleoside phosphate metabolic processGO:00067533380.032
organonitrogen compound biosynthetic processGO:19015661920.032
organic acid transportGO:00158491010.031
amide transportGO:00428861380.031
nitrogen compound transportGO:00717052710.031
endomembrane system organizationGO:00102561470.031
regulation of blood pressureGO:0008217930.031
apoptotic signaling pathwayGO:00971903060.031
negative regulation of cellular protein metabolic processGO:00322692470.031
monocarboxylic acid metabolic processGO:00327871910.031
Human Mouse
divalent inorganic cation transportGO:00725111780.031
regulation of transferase activityGO:00513382630.030
inorganic cation transmembrane transportGO:00986622070.030
regulation of intracellular transportGO:00323861590.030
regulation of secretionGO:00510462740.030
regulation of kinase activityGO:00435492490.030
regulation of establishment of protein localizationGO:00702011810.030
protein maturationGO:00516041760.030
cation homeostasisGO:00550802120.030
carbohydrate derivative biosynthetic processGO:19011371830.029
response to radiationGO:00093141650.028
maintenance of locationGO:0051235890.028
sensory perception of light stimulusGO:0050953540.028
peptide transportGO:00158331330.027
negative regulation of cell proliferationGO:00082852960.027
response to growth factorGO:00708481980.027
regulation of cell cycleGO:00517262810.026
carbohydrate metabolic processGO:00059752300.026
Mouse
carboxylic acid biosynthetic processGO:0046394860.026
Mouse
lymphocyte differentiationGO:00300982420.026
regulation of cell motilityGO:20001452360.026
cytoplasmic transportGO:00164822340.025
response to lipopolysaccharideGO:00324961280.025
carboxylic acid transportGO:00469421000.025
ossificationGO:00015032160.025
organophosphate catabolic processGO:00464342320.025
circulatory system processGO:00030131970.025
positive regulation of protein transportGO:0051222930.024
negative regulation of protein metabolic processGO:00512482820.024
hormone secretionGO:00468791280.024
membrane lipid biosynthetic processGO:0046467320.024
inorganic anion transportGO:0015698430.024
regulation of adaptive immune responseGO:0002819900.024
regulation of organelle organizationGO:00330432890.024
peptidyl amino acid modificationGO:00181933360.024
response to nutrient levelsGO:00316671090.024
regulation of t cell activationGO:00508631700.024
response to molecule of bacterial originGO:00022371430.024
muscle contractionGO:00069361010.024
regulation of inflammatory responseGO:00507271470.024
muscle cell differentiationGO:00426922610.024
regulation of hydrolase activityGO:00513362460.023
regulation of mitotic cell cycleGO:00073461260.023
cellular response to external stimulusGO:0071496880.023
forebrain developmentGO:00309003020.023
purine nucleotide metabolic processGO:00061633020.023
intracellular protein transportGO:00068862040.023
hormone metabolic processGO:0042445860.023
small gtpase mediated signal transductionGO:0007264970.023
glycerolipid metabolic processGO:00464861220.023
response to extracellular stimulusGO:00099911270.023
regulation of defense responseGO:00313472330.023
locomotory behaviorGO:00076261950.023
regulation of lymphocyte activationGO:00512492400.023
organic acid biosynthetic processGO:0016053860.022
Mouse
glycosyl compound catabolic processGO:19016582060.022
glycosyl compound metabolic processGO:19016572460.022
Human
action potentialGO:0001508780.022
epithelial tube morphogenesisGO:00605623030.022
negative regulation of cellular amine metabolic processGO:003323910.022
smooth muscle contractionGO:0006939440.022
transmission of nerve impulseGO:0019226760.022
cellular response to extracellular stimulusGO:0031668810.022
positive regulation of mapk cascadeGO:00434101700.022
negative regulation of cell cycleGO:00457861230.022
regulation of membrane potentialGO:00423911920.022
sodium ion transportGO:0006814730.021
positive regulation of transferase activityGO:00513471670.021
striated muscle tissue developmentGO:00147062930.021
ribonucleotide metabolic processGO:00092592910.021
fat cell differentiationGO:00454441600.021
innate immune responseGO:00450871570.021
dna metabolic processGO:00062593030.021
ribonucleotide catabolic processGO:00092612080.021
lipid localizationGO:00108761260.021
detection of stimulusGO:0051606840.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
positive regulation of apoptotic processGO:00430652170.020
negative regulation of phosphorylationGO:00423261660.020
protein modification by small protein conjugation or removalGO:00706472070.020
learning or memoryGO:00076111480.020
cellular response to organonitrogen compoundGO:00714171450.020
hexose metabolic processGO:0019318980.020
muscle system processGO:00030121410.020
ear developmentGO:00435832000.020
organic anion transportGO:00157111370.020
regulation of protein kinase activityGO:00458592320.020
sensory organ morphogenesisGO:00905962420.020
multicellular organismal homeostasisGO:00488711640.020
spermatogenesisGO:00072832840.020
positive regulation of cell deathGO:00109422240.020
purine ribonucleoside metabolic processGO:00461282410.020
cytokine productionGO:00018163190.020
negative regulation of phosphorus metabolic processGO:00105631840.019
regulation of sequence specific dna binding transcription factor activityGO:00510901060.019
response to acid chemicalGO:00011011110.019
Human
regulation of protein localizationGO:00328802310.019
regulation of system processGO:00440572000.019
cellular response to growth factor stimulusGO:00713631970.019
nucleoside triphosphate catabolic processGO:00091432050.019
protein targetingGO:00066051430.019
sphingolipid metabolic processGO:0006665450.019
positive regulation of kinase activityGO:00336741550.019
regulation of proteolysisGO:00301621640.018
glucose homeostasisGO:00425931280.018
ribose phosphate metabolic processGO:00196932910.018
purine containing compound metabolic processGO:00725213110.018
regulation of tube sizeGO:0035150570.018
renal system developmentGO:00720012250.018
cognitionGO:00508901490.018
regulation of phospholipid biosynthetic processGO:007107130.018
sequestering of calcium ionGO:0051208180.018
glycoprotein metabolic processGO:00091001160.018
regulation of apoptotic signaling pathwayGO:20012331970.018
regulation of protein serine threonine kinase activityGO:00719001570.018
synaptic transmissionGO:00072683290.018
cellular response to cytokine stimulusGO:00713451890.018
purine ribonucleotide catabolic processGO:00091542080.018
negative regulation of molecular functionGO:00440922580.017
regulation of endocytosisGO:0030100690.017
positive regulation of erk1 and erk2 cascadeGO:0070374470.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
mitotic cell cycleGO:00002781950.017
negative regulation of cellular amino acid metabolic processGO:004576300.017
organelle localizationGO:00516401790.017
visual perceptionGO:0007601520.017
striated muscle contractionGO:0006941450.017
exocytosisGO:00068871210.017
purine ribonucleotide metabolic processGO:00091502900.017
neural precursor cell proliferationGO:00613511210.017
cellular protein complex assemblyGO:00436231160.017
protein secretionGO:00093061110.017
protein processingGO:00164851630.017
regulation of cytoplasmic transportGO:19036491120.017
regulation of cellular catabolic processGO:00313292420.017
epithelial cell proliferationGO:00506731740.017
regulation of transmembrane transportGO:00347621280.017
anion transmembrane transportGO:0098656710.017
positive regulation of cytokine productionGO:00018191740.017
small molecule biosynthetic processGO:00442831320.017
Mouse
positive regulation of protein kinase activityGO:00458601440.017
nucleocytoplasmic transportGO:00069131390.017
cellular ion homeostasisGO:00068731650.016
cellular response to nutrient levelsGO:0031669640.016
divalent inorganic cation homeostasisGO:00725071380.016
negative regulation of protein modification processGO:00314001630.016
respiratory system developmentGO:00605411900.016
reactive oxygen species metabolic processGO:0072593840.016
chromatin modificationGO:00165681870.016
negative regulation of hormone metabolic processGO:003235140.016
regulation of calcium ion transportGO:0051924690.016
protein importGO:00170381010.016
chloride transportGO:0006821320.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
organophosphate biosynthetic processGO:00904071220.016
negative regulation of immune effector processGO:0002698550.016
peptide hormone secretionGO:00300721090.016
protein catabolic processGO:00301632210.016
regulation of lipid biosynthetic processGO:0046890540.016
Rat
angiogenesisGO:00015252010.016
monosaccharide metabolic processGO:00059961060.016
Mouse
regulation of homeostatic processGO:00328441820.016
endocytosisGO:00068971680.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
nucleoside phosphate catabolic processGO:19012922220.015
engulfment of apoptotic cellGO:004365230.015
protein localization to membraneGO:00726571080.015
cell adhesionGO:00071553290.015
fatty acid derivative metabolic processGO:1901568330.015
Human
purine ribonucleoside catabolic processGO:00461302050.015
gland developmentGO:00487323300.015
positive regulation of cell motilityGO:20001471160.015
membrane lipid metabolic processGO:0006643530.015
regulation of mapk cascadeGO:00434082480.015
placenta developmentGO:00018901400.015
sphingolipid biosynthetic processGO:0030148260.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
glycerolipid biosynthetic processGO:0045017500.015
negative regulation of execution phase of apoptosisGO:190011840.015
nuclear transportGO:00511691390.015
carbohydrate biosynthetic processGO:0016051740.015
Mouse
antibacterial peptide biosynthetic processGO:000278020.015
purine nucleoside catabolic processGO:00061522050.015
peptidyl serine modificationGO:0018209830.015
carbohydrate homeostasisGO:00335001280.015
regulation of anatomical structure sizeGO:00900661780.015
positive regulation of ion transportGO:0043270650.015
muscle tissue developmentGO:00605373080.015
cellular response to organic cyclic compoundGO:0071407870.015
peptidyl serine phosphorylationGO:0018105740.015
hematopoietic progenitor cell differentiationGO:00022441430.015
leukocyte migrationGO:00509001240.015
positive regulation of cellular catabolic processGO:00313311480.015
stress activated protein kinase signaling cascadeGO:0031098810.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
wound healingGO:00420601570.015
phagocytosisGO:0006909660.014
steroid biosynthetic processGO:0006694470.014
Rat
positive regulation of calcium ion transportGO:0051928270.014
purine nucleoside metabolic processGO:00422782410.014
symbiosis encompassing mutualism through parasitismGO:0044403830.014
regulation of blood vessel sizeGO:0050880560.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
nucleoside triphosphate metabolic processGO:00091412300.014
epithelial cell developmentGO:00020641590.014
regulation of cellular response to stressGO:00801351590.014
purine nucleotide catabolic processGO:00061952110.014
digestive tract developmentGO:00485651900.014
lipid homeostasisGO:0055088630.014
regulation of systemic arterial blood pressureGO:0003073610.014
lymphocyte mediated immunityGO:00024491390.014
heterocycle catabolic processGO:00467002800.014
positive regulation of protein phosphorylationGO:00019342420.014
adult locomotory behaviorGO:0008344910.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
ribonucleoside catabolic processGO:00424542060.014
cellular macromolecule catabolic processGO:00442652060.014
leukocyte proliferationGO:00706611720.014
positive regulation of hydrolase activityGO:00513451480.014
rhythmic processGO:00485111740.014
protein polymerizationGO:0051258570.014
nucleoside catabolic processGO:00091642060.014
response to drugGO:0042493750.014
regulation of ion transmembrane transportGO:00347651190.014
cellular response to lipidGO:00713961450.014
calcium ion homeostasisGO:00550741270.014
heart morphogenesisGO:00030071780.014
homeostasis of number of cellsGO:00488722100.014
organonitrogen compound catabolic processGO:19015652640.014
digestive system developmentGO:00551232000.014
regulation of myeloid cell differentiationGO:0045637960.014
protein ubiquitinationGO:00165671710.013
negative regulation of cell activationGO:00508661110.013
positive regulation of defense responseGO:00313491240.013
monocarboxylic acid biosynthetic processGO:0072330610.013
ribonucleoside metabolic processGO:00091192450.013
positive regulation of cell cycleGO:0045787920.013
cell activation involved in immune responseGO:00022631260.013
regulation of epithelial cell proliferationGO:00506781410.013
glycoprotein biosynthetic processGO:0009101890.013
morphogenesis of a branching epitheliumGO:00611381930.013
response to inorganic substanceGO:0010035960.013
gliogenesisGO:00420631410.013
cellular carbohydrate metabolic processGO:00442621190.013
regulation of endopeptidase activityGO:0052548890.013
positive regulation of vasoconstrictionGO:004590740.013
gonad developmentGO:00084061410.013
positive regulation of cytokine secretionGO:0050715410.013
mitotic cell cycle processGO:19030471590.013
cellular response to acid chemicalGO:0071229680.013
Human
erk1 and erk2 cascadeGO:0070371770.013
vascular process in circulatory systemGO:0003018620.013
lipid transportGO:0006869980.013
negative regulation of phosphate metabolic processGO:00459361840.013
positive regulation of cell migrationGO:00303351090.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
skeletal system developmentGO:00015013560.013
positive regulation of cell developmentGO:00107202370.013
cytokine mediated signaling pathwayGO:00192211150.013
cellular response to hexose stimulusGO:0071331470.013
development of primary sexual characteristicsGO:00451371430.013
adult behaviorGO:00305341350.013
activation of immune responseGO:00022531380.013
regulation of multi organism processGO:00439001110.013
regulation of protein secretionGO:0050708820.013
negative regulation of multi organism processGO:0043901680.013
carbohydrate derivative catabolic processGO:19011362310.013
protein modification by small protein conjugationGO:00324461870.013
positive regulation of programmed cell deathGO:00430682180.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
regulation of engulfment of apoptotic cellGO:190107420.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.012
b cell activationGO:00421131610.012
negative regulation of cellular component organizationGO:00511291940.012
regulation of hormone secretionGO:0046883880.012
chromatin organizationGO:00063252060.012
protein localization to organelleGO:00333651850.012
cellular metal ion homeostasisGO:00068751510.012
chemotaxisGO:00069352470.012
molting cycleGO:0042303900.012
positive regulation of lymphocyte activationGO:00512511400.012
glucose metabolic processGO:0006006920.012
positive regulation of organelle organizationGO:00106381280.012
cellular response to biotic stimulusGO:0071216920.012
cytokine secretionGO:0050663720.012
purine containing compound catabolic processGO:00725232130.012
neuronal action potentialGO:0019228540.012
phosphatidylethanolamine biosynthetic processGO:000664620.012
sulfur compound metabolic processGO:00067901000.012
regulation of cell cycle processGO:00105641600.012
male gamete generationGO:00482322850.012
cell fate commitmentGO:00451652100.012
myelinationGO:0042552740.012
positive regulation of nucleotide metabolic processGO:00459811140.012
negative regulation of homeostatic processGO:0032845710.012
cellular response to inorganic substanceGO:0071241370.012
regulation of cytoskeleton organizationGO:00514931220.012
myeloid cell homeostasisGO:00022621140.012
stress activated mapk cascadeGO:0051403800.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
positive regulation of immune effector processGO:00026991070.012
actin polymerization or depolymerizationGO:0008154540.012
response to organophosphorusGO:0046683220.012
Human
androgen biosynthetic processGO:000670240.012
regulation of purine nucleotide catabolic processGO:00331211220.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
alpha beta t cell activationGO:0046631910.012
myeloid leukocyte differentiationGO:00025731190.011
cell substrate adhesionGO:00315891300.011
positive regulation of protein modification processGO:00314012990.011
nuclear importGO:0051170950.011
axonogenesisGO:00074092740.011
negative regulation of macrophage apoptotic processGO:200011030.011
sequestering of metal ionGO:0051238190.011
regulation of ion homeostasisGO:2000021640.011
positive regulation of nervous system developmentGO:00519622210.011
leukocyte mediated immunityGO:00024431740.011
protein import into nucleusGO:0006606950.011
metal ion homeostasisGO:00550651890.011
response to transforming growth factor betaGO:0071559880.011
acid secretionGO:0046717330.011
nucleoside monophosphate metabolic processGO:0009123850.011
positive regulation of cell activationGO:00508671580.011
negative regulation of intracellular signal transductionGO:19025321670.011
cytokinetic processGO:003250620.011
protein localization to nucleusGO:00345041210.011
midgut developmentGO:000749440.011
regulation of interleukin 8 productionGO:003267730.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
monocarboxylic acid transportGO:0015718440.011
leukocyte activation involved in immune responseGO:00023661260.011
cytokine biosynthetic processGO:0042089680.011
positive regulation of protein secretionGO:0050714520.011
jnk cascadeGO:0007254720.011
multi multicellular organism processGO:00447061090.011
establishment of protein localization to organelleGO:00725941180.011
sulfur compound biosynthetic processGO:0044272370.011
cell type specific apoptotic processGO:00972852680.011
regulation of protein processingGO:0070613960.011
camera type eye developmentGO:00430102660.011
skeletal muscle organ developmentGO:00605381630.011
hydrogen ion transmembrane transportGO:1902600250.011
single fertilizationGO:0007338820.011
protein lipidationGO:0006497280.011
cellular response to lipopolysaccharideGO:0071222770.011
single organism nuclear importGO:1902593950.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
negative regulation of protein phosphorylationGO:00019331260.011
positive regulation of muscle contractionGO:0045933100.011
nucleoside metabolic processGO:00091162460.011
associative learningGO:0008306610.011
norepinephrine transportGO:001587420.011
regulation of monocyte chemotaxisGO:009002530.011
regulation of nucleocytoplasmic transportGO:0046822730.011
acute inflammatory responseGO:0002526410.011
peptide secretionGO:00027901140.011
phospholipid metabolic processGO:0006644870.011
adaptive immune responseGO:00022501550.011
response to peptideGO:19016521360.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
glial cell differentiationGO:00100011310.011
positive regulation of leukocyte differentiationGO:1902107860.011
hindbrain developmentGO:00309021280.010
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.010
positive regulation of proteolysisGO:0045862850.010
cellular response to starvationGO:0009267570.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
small molecule catabolic processGO:0044282710.010
negative regulation of response to woundingGO:1903035770.010
positive regulation of wnt signaling pathwayGO:0030177450.010
cytokine metabolic processGO:0042107710.010
myotube differentiationGO:00149021050.010
germ cell developmentGO:00072811850.010
fertilizationGO:00095661270.010
regulation of intracellular protein transportGO:0033157820.010
regulation of leukocyte differentiationGO:19021051590.010
immune response regulating signaling pathwayGO:00027641250.010
cholesterol homeostasisGO:0042632440.010
t cell mediated immunityGO:0002456500.010
regulation of peptidase activityGO:0052547960.010
inorganic anion transmembrane transportGO:0098661290.010
positive regulation of intracellular transportGO:0032388700.010
positive regulation of inflammatory responseGO:0050729470.010
regulation of neuron differentiationGO:00456642810.010
regulation of fat cell differentiationGO:0045598810.010

Akr1c18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.019
disease of anatomical entityDOID:700.019
disease of metabolismDOID:001466700.016
viral infectious diseaseDOID:93400.011
human immunodeficiency virus infectious diseaseDOID:52600.011
disease by infectious agentDOID:005011700.011
musculoskeletal system diseaseDOID:1700.010