Mus musculus

0 known processes

Nae1

NEDD8 activating enzyme E1 subunit 1

(Aliases: MGC29435,59kDa,MGC36437,MGC36630,Appbp1)

Nae1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of synaptic growth at neuromuscular junctionGO:000858240.529
microtubule cytoskeleton organizationGO:00002261570.397
protein modification by small protein conjugation or removalGO:00706472070.291
Yeast
microtubule based processGO:00070172360.273
regulation of cell cycle processGO:00105641600.236
carbohydrate derivative catabolic processGO:19011362310.215
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.180
male gamete generationGO:00482322850.168
mitotic cell cycle processGO:19030471590.164
proteasomal protein catabolic processGO:0010498980.157
dna repairGO:00062811070.144
regulation of anatomical structure sizeGO:00900661780.129
spermatid differentiationGO:00485151150.128
protein localization to nuclear envelopeGO:009043520.126
mitotic cell cycleGO:00002781950.123
modification dependent protein catabolic processGO:00199411330.120
cellular response to dna damage stimulusGO:00069742070.118
regulation of cell cycle phase transitionGO:1901987770.117
dna damage checkpointGO:0000077260.110
cellular macromolecule catabolic processGO:00442652060.099
purine containing compound catabolic processGO:00725232130.098
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.097
glycosyl compound catabolic processGO:19016582060.096
ribose phosphate metabolic processGO:00196932910.096
organic cyclic compound catabolic processGO:19013612950.092
nucleoside phosphate catabolic processGO:19012922220.087
proteolysis involved in cellular protein catabolic processGO:00516031470.086
purine ribonucleotide metabolic processGO:00091502900.084
regulation of ion transmembrane transportGO:00347651190.083
regulation of cell cycleGO:00517262810.082
stem cell developmentGO:00488642190.080
modification dependent macromolecule catabolic processGO:00436321330.078
synaptic transmissionGO:00072683290.078
nucleotide metabolic processGO:00091173320.076
protein catabolic processGO:00301632210.075
endomembrane system organizationGO:00102561470.075
cellular protein catabolic processGO:00442571550.074
spermatogenesisGO:00072832840.074
regulation of cell migrationGO:00303342190.074
ribonucleoside triphosphate catabolic processGO:00092031990.072
regulation of cellular response to growth factor stimulusGO:0090287820.072
dna integrity checkpointGO:0031570280.071
regulation of cellular component sizeGO:00325351210.068
cell cycle checkpointGO:0000075470.066
purine nucleotide catabolic processGO:00061952110.066
regulation of protein catabolic processGO:00421761080.065
spermatid developmentGO:00072861080.064
regulation of mitotic cell cycle phase transitionGO:1901990730.062
glycosyl compound metabolic processGO:19016572460.061
nucleoside metabolic processGO:00091162460.059
cell divisionGO:00513011200.059
germ cell developmentGO:00072811850.059
organelle localizationGO:00516401790.058
immune effector processGO:00022523210.058
nucleoside phosphate metabolic processGO:00067533380.057
ribonucleoside triphosphate metabolic processGO:00091992200.056
protein modification by small protein conjugationGO:00324461870.055
Yeast
purine ribonucleoside catabolic processGO:00461302050.054
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.054
macromolecule catabolic processGO:00090572810.054
dna metabolic processGO:00062593030.053
negative regulation of cell cycleGO:00457861230.051
organonitrogen compound catabolic processGO:19015652640.051
regulation of mitotic cell cycleGO:00073461260.050
nucleoside triphosphate metabolic processGO:00091412300.050
regulation of transmembrane transportGO:00347621280.049
regulation of cellular catabolic processGO:00313292420.048
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.047
ribonucleotide catabolic processGO:00092612080.047
purine ribonucleoside metabolic processGO:00461282410.046
negative regulation of cell cycle processGO:0010948690.042
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.042
purine containing compound metabolic processGO:00725213110.042
negative regulation of protein metabolic processGO:00512482820.042
regulation of cell motilityGO:20001452360.041
positive regulation of cellular catabolic processGO:00313311480.041
membrane organizationGO:00610242450.041
synapse organizationGO:00508081250.040
regulation of organelle organizationGO:00330432890.040
sperm individualizationGO:000729110.039
oocyte constructionGO:000730820.037
purine ribonucleotide catabolic processGO:00091542080.037
positive regulation of hydrolase activityGO:00513451480.036
stem cell differentiationGO:00488632680.036
ribonucleoside catabolic processGO:00424542060.036
purine ribonucleoside triphosphate metabolic processGO:00092052200.035
nucleoside triphosphate catabolic processGO:00091432050.035
establishment of organelle localizationGO:00516561220.035
heterocycle catabolic processGO:00467002800.035
regulation of kinase activityGO:00435492490.035
organelle assemblyGO:00709251770.035
negative regulation of cell cycle phase transitionGO:1901988480.035
purine nucleoside triphosphate catabolic processGO:00091462030.033
negative regulation of mitotic cell cycleGO:0045930580.033
axonogenesisGO:00074092740.033
rna processingGO:00063961050.033
ribonucleoside metabolic processGO:00091192450.032
negative regulation of cellular component organizationGO:00511291940.032
double strand break repairGO:0006302480.032
transmembrane transportGO:00550854120.032
protein neddylationGO:004511610.032
Yeast
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.032
ubiquitin dependent protein catabolic processGO:00065111290.031
development of primary sexual characteristicsGO:00451371430.031
ion transmembrane transportGO:00342203610.030
regulation of cell sizeGO:0008361720.030
organophosphate catabolic processGO:00464342320.030
organelle fissionGO:00482851700.029
transforming growth factor beta receptor signaling pathwayGO:0007179710.029
protein localization to organelleGO:00333651850.029
ribonucleotide metabolic processGO:00092592910.029
apoptotic signaling pathwayGO:00971903060.029
cellularizationGO:000734910.028
regulation of proteasomal protein catabolic processGO:0061136460.028
response to peptideGO:19016521360.027
regulation of protein kinase activityGO:00458592320.027
response to growth factorGO:00708481980.027
regulation of synapse assemblyGO:0051963290.027
cardiac muscle contractionGO:0060048320.026
response to light stimulusGO:00094161350.026
cellular response to transforming growth factor beta stimulusGO:0071560880.026
negative regulation of mitotic cell cycle phase transitionGO:1901991450.026
protein sumoylationGO:0016925140.026
nucleotide catabolic processGO:00091662170.025
dna recombinationGO:0006310920.025
regulation of cellular component biogenesisGO:00440871810.025
g1 s transition of mitotic cell cycleGO:0000082570.025
regulation of mapk cascadeGO:00434082480.024
positive regulation of cellular protein catabolic processGO:1903364340.024
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.024
negative regulation of cellular protein metabolic processGO:00322692470.024
regulation of cell projection organizationGO:00313442060.024
negative regulation of phosphorus metabolic processGO:00105631840.024
spindle organizationGO:0007051280.023
positive regulation of protein complex assemblyGO:0031334450.023
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.023
response to transforming growth factor betaGO:0071559880.023
purine nucleotide metabolic processGO:00061633020.023
regulation of vesicle mediated transportGO:00606271390.023
regulation of cellular ketone metabolic processGO:0010565660.023
mapk cascadeGO:00001652810.022
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.022
synaptonemal complex organizationGO:0070193150.022
cellular amino acid metabolic processGO:00065201030.022
cellular amine metabolic processGO:0044106440.021
regulation of response to dna damage stimulusGO:2001020340.021
regulation of protein stabilityGO:0031647520.021
single fertilizationGO:0007338820.021
nucleobase containing small molecule metabolic processGO:00550863520.021
regulation of cellular amine metabolic processGO:0033238200.021
regulation of bindingGO:00510981110.021
cation transportGO:00068123990.021
guanosine containing compound metabolic processGO:19010681440.021
regulation of transporter activityGO:0032409570.021
positive regulation of protein catabolic processGO:0045732600.021
negative regulation of synapse assemblyGO:005196430.021
nucleus localizationGO:0051647200.021
positive regulation of dna templated transcription elongationGO:003278620.020
negative regulation of cell motilityGO:2000146610.020
negative regulation of intracellular signal transductionGO:19025321670.020
body morphogenesisGO:0010171450.020
regulation of nucleotide catabolic processGO:00308111220.020
oocyte axis specificationGO:000730920.020
peptidyl amino acid modificationGO:00181933360.019
positive regulation of atpase activityGO:003278130.019
methylationGO:00322591340.019
cellular component assembly involved in morphogenesisGO:00109271390.019
gonad developmentGO:00084061410.019
regulation of cellular protein catabolic processGO:1903362610.019
positive regulation of proteolysisGO:0045862850.019
posttranscriptional regulation of gene expressionGO:00106081550.019
aromatic compound catabolic processGO:00194392860.019
synaptic growth at neuromuscular junctionGO:005112460.018
regulation of transferase activityGO:00513382630.018
negative regulation of cell developmentGO:00107211690.018
dendrite developmentGO:00163581150.018
ras protein signal transductionGO:0007265770.018
centrosome cycleGO:0007098230.018
regulation of ras gtpase activityGO:0032318880.017
positive regulation of transferase activityGO:00513471670.017
negative regulation of phosphate metabolic processGO:00459361840.017
nucleoside catabolic processGO:00091642060.017
negative regulation of phosphorylationGO:00423261660.017
nucleotide excision repairGO:0006289130.017
cellular nitrogen compound catabolic processGO:00442702800.017
regulation of ion transmembrane transporter activityGO:0032412540.017
positive regulation of cell cycle processGO:0090068610.017
muscle system processGO:00030121410.017
cell cycle g1 s phase transitionGO:0044843570.017
multi organism behaviorGO:0051705620.017
response to organonitrogen compoundGO:00102432460.016
response to insulinGO:00328681000.016
positive regulation of nucleotide metabolic processGO:00459811140.016
positive regulation of nucleotide catabolic processGO:0030813880.016
guanosine containing compound catabolic processGO:19010691440.016
cellular response to growth factor stimulusGO:00713631970.016
cellular ketone metabolic processGO:0042180840.016
purine nucleoside catabolic processGO:00061522050.016
positive regulation of protein phosphorylationGO:00019342420.016
covalent chromatin modificationGO:00165691630.016
maternal determination of anterior posterior axis embryoGO:000835820.016
regulation of cellular response to stressGO:00801351590.016
regulation of nucleotide metabolic processGO:00061401690.015
atp metabolic processGO:0046034750.015
nuclear divisionGO:00002801580.015
actin mediated cell contractionGO:0070252150.015
positive regulation of nucleoside metabolic processGO:0045979910.015
cell maturationGO:00484691270.015
purine nucleoside metabolic processGO:00422782410.015
striated muscle tissue developmentGO:00147062930.015
amine metabolic processGO:0009308450.015
purine nucleoside monophosphate catabolic processGO:0009128580.015
rna splicingGO:0008380540.015
multicellular organismal protein catabolic processGO:004425410.015
small gtpase mediated signal transductionGO:0007264970.014
negative regulation of cellular response to growth factor stimulusGO:0090288460.014
protein ubiquitinationGO:00165671710.014
regulation of ion transportGO:00432692150.014
muscle cell proliferationGO:0033002520.014
endocytosisGO:00068971680.014
meiotic cell cycleGO:00513211220.013
regulation of protein localizationGO:00328802310.013
positive regulation of cellular component biogenesisGO:0044089940.013
chemotaxisGO:00069352470.013
tor signalingGO:0031929210.013
neuron projection guidanceGO:00974851410.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
regulation of protein maturationGO:1903317960.013
cation transmembrane transportGO:00986552660.013
regulation of purine nucleotide catabolic processGO:00331211220.012
mitotic cell cycle checkpointGO:0007093310.012
microtubule severingGO:005101350.012
negative regulation of pathway restricted smad protein phosphorylationGO:006039410.012
skeletal muscle cell differentiationGO:0035914660.012
positive regulation of protein modification processGO:00314012990.012
digestive system developmentGO:00551232000.012
positive regulation of cellular amine metabolic processGO:003324050.012
response to radiationGO:00093141650.012
positive regulation of protein kinase activityGO:00458601440.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
stem cell divisionGO:0017145300.011
gtp metabolic processGO:00460391440.011
axon guidanceGO:00074111410.011
rho protein signal transductionGO:0007266320.011
regulation of cell divisionGO:0051302760.011
adult behaviorGO:00305341350.011
regulation of protein processingGO:0070613960.011
multicellular organismal agingGO:0010259240.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
stem cell maintenanceGO:00198271300.011
negative regulation of cellular catabolic processGO:0031330470.011
negative regulation of nervous system developmentGO:00519611560.011
cellular response to gonadotropin stimulusGO:007137140.011
cellular response to organonitrogen compoundGO:00714171450.011
establishment or maintenance of cell polarityGO:0007163860.011
nucleocytoplasmic transportGO:00069131390.011
lipid transportGO:0006869980.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
digestive tract morphogenesisGO:00485461470.010
regulation of epithelial cell proliferationGO:00506781410.010
regulation of nuclear divisionGO:0051783560.010
cognitionGO:00508901490.010
cytoplasmic transportGO:00164822340.010
negative regulation of cell proliferationGO:00082852960.010
regulation of neuron differentiationGO:00456642810.010
trna processingGO:0008033110.010
centrosome organizationGO:0051297260.010
mrna splicing via spliceosomeGO:0000398430.010
calcium ion transmembrane transportGO:0070588850.010

Nae1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.022
disease of anatomical entityDOID:700.022
physical disorderDOID:008001500.017
musculoskeletal system diseaseDOID:1700.014
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.014
limb girdle muscular dystrophyDOID:1172400.012
muscular dystrophyDOID:988400.012
myopathyDOID:42300.012
sensory system diseaseDOID:005015500.010
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010