| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.218 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.218 | |
| protein ubiquitination | GO:0016567 | 171 | 0.123 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.092 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.071 | |
| membrane organization | GO:0061024 | 245 | 0.067 | |
| iron sulfur cluster assembly | GO:0016226 | 3 | 0.065 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.063 | |
| maintenance of location | GO:0051235 | 89 | 0.059 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.058 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.051 | |
| organelle fusion | GO:0048284 | 28 | 0.050 | |
| vesicle organization | GO:0016050 | 60 | 0.049 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.048 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.047 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.041 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.040 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.040 | |
| intra golgi vesicle mediated transport | GO:0006891 | 1 | 0.040 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.040 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.037 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.036 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.035 | |
| t cell activation | GO:0042110 | 289 | 0.034 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.033 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.032 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.031 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.031 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.030 | |
| microtubule based process | GO:0007017 | 236 | 0.030 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.029 | |
| calcium ion transport into cytosol | GO:0060402 | 48 | 0.028 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.028 | |
| dephosphorylation | GO:0016311 | 129 | 0.028 | |
| calcium ion transport | GO:0006816 | 159 | 0.028 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.027 | |
| membrane fusion | GO:0061025 | 38 | 0.027 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.027 | |
| regulation of calcium ion transport into cytosol | GO:0010522 | 31 | 0.027 | |
| rna interference | GO:0016246 | 2 | 0.027 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.026 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.026 | |
| trna wobble uridine modification | GO:0002098 | 2 | 0.026 | |
| endomembrane system organization | GO:0010256 | 147 | 0.026 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.026 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.026 | |
| golgi to endosome transport | GO:0006895 | 3 | 0.025 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.025 | |
| synapse organization | GO:0050808 | 125 | 0.025 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.025 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.025 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.025 | |
| cytosolic calcium ion transport | GO:0060401 | 48 | 0.025 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.025 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.024 | |
| trna wobble base modification | GO:0002097 | 2 | 0.024 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.023 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.023 | |
| regulation of secretion | GO:0051046 | 274 | 0.023 | |
| vesicle fusion | GO:0006906 | 16 | 0.023 | |
| organelle fission | GO:0048285 | 170 | 0.023 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.023 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.023 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.022 | |
| dna repair | GO:0006281 | 107 | 0.022 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.022 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.022 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.022 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.022 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.022 | |
| protein polymerization | GO:0051258 | 57 | 0.022 | |
| regulation of arp2 3 complex mediated actin nucleation | GO:0034315 | 1 | 0.022 | |
| histone modification | GO:0016570 | 159 | 0.021 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.021 | |
| organelle localization | GO:0051640 | 179 | 0.021 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.021 | |
| neuron death | GO:0070997 | 154 | 0.020 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.020 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.019 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.019 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 70 | 0.019 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.019 | |
| nuclear division | GO:0000280 | 158 | 0.019 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.019 | |
| regulation of actin nucleation | GO:0051125 | 4 | 0.019 | |
| protein maturation | GO:0051604 | 176 | 0.019 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.019 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.019 | |
| vesicle localization | GO:0051648 | 86 | 0.019 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.019 | |
| cellular homeostasis | GO:0019725 | 240 | 0.019 | |
| protein catabolic process | GO:0030163 | 221 | 0.018 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.018 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.018 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.018 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.018 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.018 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.018 | |
| synapse assembly | GO:0007416 | 56 | 0.018 | |
| amine metabolic process | GO:0009308 | 45 | 0.018 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.018 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.017 | |
| negative regulation of protein transport | GO:0051224 | 46 | 0.017 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.017 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.017 | |
| cell fate commitment | GO:0045165 | 210 | 0.017 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.017 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.017 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.017 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.017 | |
| sensory system development | GO:0048880 | 3 | 0.017 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.016 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.016 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.016 | |
| cell adhesion | GO:0007155 | 329 | 0.016 | |
| monosaccharide metabolic process | GO:0005996 | 106 | 0.016 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.016 | |
| macroautophagy | GO:0016236 | 21 | 0.016 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.016 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.016 | |
| lateral line system development | GO:0048925 | 1 | 0.015 | |
| hexose metabolic process | GO:0019318 | 98 | 0.015 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.015 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.015 | |
| lipid localization | GO:0010876 | 126 | 0.015 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 65 | 0.015 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.015 | |
| cytokine production | GO:0001816 | 319 | 0.015 | |
| regulation of neuron death | GO:1901214 | 134 | 0.015 | |
| regulation of cell activation | GO:0050865 | 289 | 0.015 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.015 | |
| establishment of melanosome localization | GO:0032401 | 11 | 0.015 | |
| dna metabolic process | GO:0006259 | 303 | 0.015 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.015 | |
| regulation of ion transport | GO:0043269 | 215 | 0.015 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.015 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.015 | |
| spermatogenesis | GO:0007283 | 284 | 0.015 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.015 | |
| response to growth factor | GO:0070848 | 198 | 0.015 | |
| regulation of ion homeostasis | GO:2000021 | 64 | 0.015 | |
| virion assembly | GO:0019068 | 1 | 0.014 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.014 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.014 | |
| organelle assembly | GO:0070925 | 177 | 0.014 | |
| protein secretion | GO:0009306 | 111 | 0.014 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.014 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.014 | |
| endocytosis | GO:0006897 | 168 | 0.014 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.014 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.014 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.014 | |
| cellular lipid catabolic process | GO:0044242 | 52 | 0.014 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.014 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.014 | |
| muscle tissue development | GO:0060537 | 308 | 0.014 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.014 | |
| nuclear transport | GO:0051169 | 139 | 0.014 | |
| protein targeting | GO:0006605 | 143 | 0.014 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.013 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.013 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.013 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.013 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.013 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.013 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.013 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.013 | |
| peptide transport | GO:0015833 | 133 | 0.013 | |
| organism emergence from protective structure | GO:0071684 | 4 | 0.013 | |
| positive regulation of t cell proliferation | GO:0042102 | 52 | 0.013 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.013 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.013 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.013 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.013 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.013 | |
| regulation of calcium ion transport | GO:0051924 | 69 | 0.013 | |
| regulation of actin filament polymerization | GO:0030833 | 38 | 0.013 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.013 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.012 | |
| dna recombination | GO:0006310 | 92 | 0.012 | |
| circadian rhythm | GO:0007623 | 114 | 0.012 | |
| positive regulation of lamellipodium organization | GO:1902745 | 3 | 0.012 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.012 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.012 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.012 | |
| negative regulation of homeostatic process | GO:0032845 | 71 | 0.012 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.012 | |
| cation homeostasis | GO:0055080 | 212 | 0.012 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.012 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.012 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.012 | |
| cation transport | GO:0006812 | 399 | 0.012 | |
| male gamete generation | GO:0048232 | 285 | 0.012 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.012 | |
| defense response to other organism | GO:0098542 | 197 | 0.012 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.012 | |
| arp2 3 complex mediated actin nucleation | GO:0034314 | 3 | 0.012 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.012 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.012 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.012 | |
| protein processing | GO:0016485 | 163 | 0.012 | |
| synaptic transmission | GO:0007268 | 329 | 0.012 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.012 | |
| hormone secretion | GO:0046879 | 128 | 0.012 | |
| peptide hormone secretion | GO:0030072 | 109 | 0.011 | |
| response to interleukin 4 | GO:0070670 | 23 | 0.011 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.011 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.011 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.011 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.011 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.011 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.011 | |
| glucose metabolic process | GO:0006006 | 92 | 0.011 | |
| leukocyte homeostasis | GO:0001776 | 79 | 0.011 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.011 | |
| regulation of hormone secretion | GO:0046883 | 88 | 0.011 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.011 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.011 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.011 | |
| multicellular organism growth | GO:0035264 | 161 | 0.011 | |
| amide transport | GO:0042886 | 138 | 0.011 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.011 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.011 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.011 | |
| skin development | GO:0043588 | 220 | 0.011 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.011 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.011 | |
| peptide secretion | GO:0002790 | 114 | 0.011 | |
| response to radiation | GO:0009314 | 165 | 0.010 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.010 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.010 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.010 | |
| release of sequestered calcium ion into cytosol | GO:0051209 | 42 | 0.010 | |
| lipid catabolic process | GO:0016042 | 69 | 0.010 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.010 | |
| regulation of feeding behavior | GO:0060259 | 3 | 0.010 | |
| intracellular protein transport | GO:0006886 | 204 | 0.010 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.010 | |
| regulation of cell growth | GO:0001558 | 91 | 0.010 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.010 | |
| uropod organization | GO:0032796 | 2 | 0.010 | |
| regulation of lamellipodium assembly | GO:0010591 | 3 | 0.010 | |
