Mus musculus

0 known processes

Dna2

DNA replication helicase 2 homolog (yeast)

(Aliases: E130315B21Rik,Dna2l,KIAA0083)

Dna2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.829
Human
protection from non homologous end joining at telomereGO:003184840.737
telomere maintenance in response to dna damageGO:004324740.713
negative regulation of mitotic cell cycle phase transitionGO:1901991450.520
cellular response to dna damage stimulusGO:00069742070.468
Human
telomere cappingGO:001623340.428
dna replicationGO:0006260520.351
Human
chromatin modificationGO:00165681870.288
negative regulation of cell cycle phase transitionGO:1901988480.267
microtubule based processGO:00070172360.259
chromatin organizationGO:00063252060.236
negative regulation of cell cycleGO:00457861230.228
dna biosynthetic processGO:0071897220.227
negative regulation of mitotic cell cycleGO:0045930580.217
mitotic cell cycleGO:00002781950.215
mitotic cell cycle processGO:19030471590.213
chromosome segregationGO:0007059480.205
regulation of mitotic cell cycleGO:00073461260.193
regulation of cell divisionGO:0051302760.188
dna endoreduplicationGO:004202340.170
regulation of cell cycleGO:00517262810.165
histone threonine phosphorylationGO:003540510.154
cellular macromolecule catabolic processGO:00442652060.150
Human
negative regulation of cellular component organizationGO:00511291940.150
cellular protein catabolic processGO:00442571550.149
organic cyclic compound catabolic processGO:19013612950.146
Human
cell divisionGO:00513011200.135
regulation of cell cycle processGO:00105641600.132
microtubule cytoskeleton organizationGO:00002261570.126
dna repairGO:00062811070.124
Human
regulation of cell cycle phase transitionGO:1901987770.117
nucleoside metabolic processGO:00091162460.117
Human
cellular nitrogen compound catabolic processGO:00442702800.114
Human
nucleobase containing small molecule metabolic processGO:00550863520.112
Human
regulation of cellular catabolic processGO:00313292420.112
purine nucleotide metabolic processGO:00061633020.111
Human
mitotic sister chromatid segregationGO:0000070140.110
regulation of mitotic cell cycle phase transitionGO:1901990730.106
dna packagingGO:0006323300.105
mitotic nuclear divisionGO:0007067480.103
organelle fissionGO:00482851700.102
female meiosis chromosome segregationGO:001632110.097
positive regulation of cell cycleGO:0045787920.097
organonitrogen compound catabolic processGO:19015652640.096
Human
translesion synthesisGO:001998510.093
cell cycle checkpointGO:0000075470.091
Human
centrosome separationGO:005129940.091
nucleoside phosphate metabolic processGO:00067533380.086
Human
regulation of nuclear cell cycle dna replicationGO:003326220.086
organelle assemblyGO:00709251770.085
nuclear divisionGO:00002801580.084
purine nucleoside metabolic processGO:00422782410.084
Human
regulation of organelle organizationGO:00330432890.083
intrinsic apoptotic signaling pathwayGO:00971931320.082
macromolecule catabolic processGO:00090572810.081
Human
positive regulation of cell deathGO:00109422240.080
nucleoside catabolic processGO:00091642060.072
Human
negative regulation of cell cycle processGO:0010948690.070
negative regulation of dna replicationGO:000815640.068
gonad developmentGO:00084061410.068
regulation of mitosisGO:0007088290.066
peptidyl amino acid modificationGO:00181933360.066
proteolysis involved in cellular protein catabolic processGO:00516031470.065
cellular amino acid metabolic processGO:00065201030.064
regulation of cellular amino acid metabolic processGO:000652150.062
aromatic compound catabolic processGO:00194392860.061
Human
protein maturationGO:00516041760.060
purine ribonucleotide metabolic processGO:00091502900.060
Human
methylationGO:00322591340.059
sister chromatid segregationGO:0000819200.059
protein catabolic processGO:00301632210.059
nucleoside phosphate catabolic processGO:19012922220.058
Human
heterocycle catabolic processGO:00467002800.057
Human
cellular ketone metabolic processGO:0042180840.057
genitalia developmentGO:0048806370.057
cellular amine metabolic processGO:0044106440.056
ribonucleoside triphosphate metabolic processGO:00091992200.055
Human
nucleoside triphosphate metabolic processGO:00091412300.055
Human
apoptotic signaling pathwayGO:00971903060.054
negative regulation of organelle organizationGO:0010639900.052
regulation of cellular amine metabolic processGO:0033238200.052
gene silencingGO:0016458380.052
positive regulation of programmed cell deathGO:00430682180.052
protein processingGO:00164851630.051
meiotic cell cycleGO:00513211220.051
ribonucleoside metabolic processGO:00091192450.051
Human
positive regulation of apoptotic processGO:00430652170.051
purine nucleoside triphosphate catabolic processGO:00091462030.048
Human
metaphase anaphase transition of mitotic cell cycleGO:000709190.048
establishment of organelle localizationGO:00516561220.047
purine ribonucleoside triphosphate metabolic processGO:00092052200.047
Human
modification dependent protein catabolic processGO:00199411330.047
synapsisGO:0007129340.046
positive regulation of cell developmentGO:00107202370.046
response to organonitrogen compoundGO:00102432460.045
carbohydrate derivative catabolic processGO:19011362310.044
Human
ribonucleotide catabolic processGO:00092612080.044
Human
ribonucleoside catabolic processGO:00424542060.044
Human
ribonucleoside triphosphate catabolic processGO:00092031990.043
Human
organophosphate catabolic processGO:00464342320.043
Human
development of primary sexual characteristicsGO:00451371430.043
positive regulation of organelle organizationGO:00106381280.042
regulation of apoptotic signaling pathwayGO:20012331970.042
mitotic cell cycle checkpointGO:0007093310.042
spindle assembly involved in mitosisGO:009030740.041
amine metabolic processGO:0009308450.041
purine ribonucleoside monophosphate metabolic processGO:0009167800.041
Human
glycosyl compound catabolic processGO:19016582060.041
Human
negative regulation of cellular amine metabolic processGO:003323910.040
positive regulation of hydrolase activityGO:00513451480.040
ribose phosphate metabolic processGO:00196932910.040
Human
nucleotide catabolic processGO:00091662170.039
Human
regulation of dna dependent dna replicationGO:009032980.039
protein localization to organelleGO:00333651850.039
mitotic recombinationGO:000631230.039
regulation of transferase activityGO:00513382630.038
purine nucleoside triphosphate metabolic processGO:00091442260.038
Human
negative regulation of cell divisionGO:0051782240.038
purine ribonucleotide catabolic processGO:00091542080.038
Human
regulation of hydrolase activityGO:00513362460.036
dna recombinationGO:0006310920.036
nucleotide metabolic processGO:00091173320.036
Human
ras protein signal transductionGO:0007265770.035
mitotic sister chromatid separationGO:005130690.035
endomembrane system organizationGO:00102561470.035
regulation of homeostatic processGO:00328441820.035
protein ubiquitinationGO:00165671710.035
dna replication independent nucleosome assemblyGO:000633610.035
nucleoside triphosphate catabolic processGO:00091432050.035
Human
positive regulation of cellular amine metabolic processGO:003324050.035
cell cycle g1 s phase transitionGO:0044843570.034
regulation of nuclear divisionGO:0051783560.034
mitotic chromosome condensationGO:000707610.033
purine nucleotide catabolic processGO:00061952110.033
Human
histone modificationGO:00165701590.033
regulation of chromosome organizationGO:0033044830.032
anatomical structure homeostasisGO:00602491450.032
cellular protein complex assemblyGO:00436231160.032
regulation of mitotic sister chromatid segregationGO:0033047120.031
regulation of cellular ketone metabolic processGO:0010565660.031
positive regulation of protein modification processGO:00314012990.031
chromosome separationGO:0051304140.031
regulation of dna replicationGO:0006275170.031
Human
regulation of cytoskeleton organizationGO:00514931220.030
covalent chromatin modificationGO:00165691630.030
positive regulation of cell cycle processGO:0090068610.030
protein polymerizationGO:0051258570.030
maintenance of locationGO:0051235890.030
purine nucleoside catabolic processGO:00061522050.029
Human
urogenital system developmentGO:00016552610.029
purine containing compound metabolic processGO:00725213110.029
Human
positive regulation of homeostatic processGO:0032846640.028
angiogenesisGO:00015252010.028
positive regulation of chromosome organizationGO:2001252330.028
cellular response to organonitrogen compoundGO:00714171450.028
purine ribonucleoside metabolic processGO:00461282410.028
Human
negative regulation of chromosome organizationGO:2001251300.027
response to radiationGO:00093141650.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.027
negative regulation of mitosisGO:0045839100.027
negative regulation of protein metabolic processGO:00512482820.027
negative regulation of cellular protein metabolic processGO:00322692470.027
glycosyl compound metabolic processGO:19016572460.027
Human
astral microtubule organizationGO:003095330.027
spindle checkpointGO:0031577120.027
cation transportGO:00068123990.027
chromatin remodeling at centromereGO:003105520.026
negative regulation of molecular functionGO:00440922580.026
b cell activationGO:00421131610.026
negative regulation of transferase activityGO:0051348850.026
protein dna complex subunit organizationGO:0071824280.026
protein oligomerizationGO:0051259670.026
ribonucleotide metabolic processGO:00092592910.026
Human
negative regulation of protein processingGO:0010955790.026
regulation of purine nucleotide catabolic processGO:00331211220.026
heterochromatin organizationGO:007082840.025
g1 s transition of mitotic cell cycleGO:0000082570.025
negative regulation of homeostatic processGO:0032845710.025
protein localization to chromosomeGO:003450260.025
ubiquitin dependent protein catabolic processGO:00065111290.025
purine ribonucleoside triphosphate catabolic processGO:00092071990.025
Human
purine nucleoside monophosphate metabolic processGO:0009126810.025
Human
dna conformation changeGO:0071103370.024
Human
centrosome cycleGO:0007098230.024
modification dependent macromolecule catabolic processGO:00436321330.024
mitotic sister chromatid cohesionGO:000706410.024
cell fate commitmentGO:00451652100.024
spermatogenesisGO:00072832840.024
cellular lipid metabolic processGO:00442553230.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
nuclear dna replicationGO:003326030.024
positive regulation of meiosis iGO:006090350.024
gland developmentGO:00487323300.024
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.023
blood vessel morphogenesisGO:00485142850.023
regulation of cellular component biogenesisGO:00440871810.023
synaptonemal complex assemblyGO:0007130130.023
regulation of nucleotide metabolic processGO:00061401690.023
proteasomal protein catabolic processGO:0010498980.023
chromatin assembly or disassemblyGO:0006333160.022
cellular homeostasisGO:00197252400.022
negative regulation of cellular amino acid metabolic processGO:004576300.022
digestive system developmentGO:00551232000.022
wnt signaling pathwayGO:00160551880.022
fertilizationGO:00095661270.021
purine containing compound catabolic processGO:00725232130.021
Human
negative regulation of sister chromatid segregationGO:003304670.021
positive regulation of purine nucleotide metabolic processGO:19005441140.021
mitochondrion organizationGO:00070051340.021
Human
dna alkylationGO:0006305430.021
negative regulation of cell proliferationGO:00082852960.021
meiotic nuclear divisionGO:00071261150.021
positive regulation of nervous system developmentGO:00519622210.020
positive regulation of nucleotide metabolic processGO:00459811140.020
regulation of protein processingGO:0070613960.020
leukocyte proliferationGO:00706611720.020
placenta developmentGO:00018901400.020
positive regulation of microtubule polymerization or depolymerizationGO:003111230.020
immune effector processGO:00022523210.020
regulation of purine nucleotide metabolic processGO:19005421690.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.020
myeloid cell differentiationGO:00300992330.020
macromolecule methylationGO:00434141200.020
regulation of histone modificationGO:0031056560.020
forebrain developmentGO:00309003020.020
meiotic chromosome segregationGO:0045132190.020
regulation of protein localizationGO:00328802310.020
lymphocyte proliferationGO:00466511640.019
positive regulation of cellular catabolic processGO:00313311480.019
rna interferenceGO:001624620.019
membrane organizationGO:00610242450.019
cell cycle g2 m phase transitionGO:0044839200.019
microtubule organizing center organizationGO:0031023280.019
regulation of proteolysisGO:00301621640.019
posttranscriptional regulation of gene expressionGO:00106081550.018
purine ribonucleoside catabolic processGO:00461302050.018
Human
spermatid differentiationGO:00485151150.018
multicellular organism growthGO:00352641610.018
hepaticobiliary system developmentGO:0061008670.018
response to organic cyclic compoundGO:00140701980.018
anion transportGO:00068201770.018
rna dependent dna replicationGO:000627830.018
microtubule cytoskeleton organization involved in mitosisGO:190285040.018
positive regulation of mitotic cell cycleGO:0045931410.018
regulation of protein kinase activityGO:00458592320.018
ribonucleoside monophosphate metabolic processGO:0009161800.018
Human
small gtpase mediated signal transductionGO:0007264970.018
positive regulation of protein serine threonine kinase activityGO:00719021060.017
leukocyte differentiationGO:00025213420.017
dna methylationGO:0006306430.017
peptidyl serine phosphorylationGO:0018105740.017
regulation of protein maturationGO:1903317960.017
negative regulation of protein maturationGO:1903318790.017
negative regulation of intracellular signal transductionGO:19025321670.017
mitotic cytokinesisGO:000028140.017
rho protein signal transductionGO:0007266320.017
regulation of nucleoside metabolic processGO:00091181300.017
double strand break repair via homologous recombinationGO:0000724210.017
dna modificationGO:0006304500.017
nucleoside monophosphate metabolic processGO:0009123850.017
Human
nitrogen compound transportGO:00717052710.017
oxidation reduction processGO:00551143420.017
cell type specific apoptotic processGO:00972852680.016
meiosis iGO:0007127600.016
regulation of wnt signaling pathwayGO:00301111230.016
morphogenesis of embryonic epitheliumGO:00163311590.016
protein modification by small protein conjugationGO:00324461870.016
regulation of secretionGO:00510462740.016
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.016
regulation of cell activationGO:00508652890.016
spindle organizationGO:0007051280.016
regulation of lymphocyte activationGO:00512492400.015
chromatin assemblyGO:0031497130.015
protein acylationGO:0043543640.015
regulation of meiosis iGO:006063170.015
positive regulation of cell divisionGO:0051781310.015
male gamete generationGO:00482322850.015
endocytosisGO:00068971680.015
blastocyst developmentGO:0001824800.015
gtp metabolic processGO:00460391440.015
regulation of map kinase activityGO:00434051200.015
spindle assembly involved in meiosisGO:009030640.015
cell adhesionGO:00071553290.015
double strand break repairGO:0006302480.014
Human
mesodermal cell migrationGO:000807840.014
histone h3 k9 acetylationGO:004397050.014
metaphase plate congressionGO:005131020.014
b cell differentiationGO:0030183780.014
regulation of defense responseGO:00313472330.014
cell agingGO:0007569350.014
regulation of cellular response to stressGO:00801351590.014
organelle localizationGO:00516401790.014
divalent metal ion transportGO:00708381720.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.014
monocarboxylic acid metabolic processGO:00327871910.014
mapk cascadeGO:00001652810.014
positive regulation of nuclear divisionGO:0051785270.014
spindle assembly involved in female meiosisGO:000705630.014
guanosine containing compound metabolic processGO:19010681440.014
cellular response to growth factor stimulusGO:00713631970.014
glucose homeostasisGO:00425931280.014
positive regulation of protein kinase activityGO:00458601440.014
regulation of nucleotide catabolic processGO:00308111220.014
negative regulation of immune system processGO:00026832090.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
response to light stimulusGO:00094161350.014
sensory perceptionGO:00076002450.013
response to growth factorGO:00708481980.013
negative regulation of nuclear divisionGO:0051784190.013
primary neural tube formationGO:0014020950.013
leukocyte activation involved in immune responseGO:00023661260.013
neuron migrationGO:00017641220.013
dna ligationGO:000626630.013
positive regulation of purine nucleotide catabolic processGO:0033123880.013
regulation of protein complex assemblyGO:0043254830.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
leukocyte mediated immunityGO:00024431740.013
mrna processingGO:0006397630.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114590.013
positive regulation of gtp catabolic processGO:0033126850.013
striated muscle myosin thick filament assemblyGO:007168810.013
carbohydrate homeostasisGO:00335001280.013
camera type eye developmentGO:00430102660.013
lymphocyte differentiationGO:00300982420.013
histone phosphorylationGO:001657290.013
gastrulationGO:00073691160.012
single fertilizationGO:0007338820.012
regulation of chromosome segregationGO:0051983210.012
atp metabolic processGO:0046034750.012
Human
guanosine containing compound catabolic processGO:19010691440.012
epithelial tube formationGO:00721751300.012
regulation of cell motilityGO:20001452360.012
reciprocal meiotic recombinationGO:0007131160.012
homeostasis of number of cellsGO:00488722100.012
chorion developmentGO:006071770.012
regulation of proteasomal protein catabolic processGO:0061136460.012
cellular response to cytokine stimulusGO:00713451890.012
positive regulation of protein complex assemblyGO:0031334450.012
humoral immune responseGO:0006959570.012
sister chromatid cohesionGO:0007062120.012
reciprocal dna recombinationGO:0035825160.012
regulation of cell cycle g2 m phase transitionGO:1902749100.012
chemotaxisGO:00069352470.012
histone acetylationGO:0016573410.012
epithelial cell proliferationGO:00506731740.012
cytokine productionGO:00018163190.012
digestive tract developmentGO:00485651900.012
positive regulation of cytoskeleton organizationGO:0051495490.012
regulation of cytokine productionGO:00018172660.012
regulation of neuron differentiationGO:00456642810.012
protein modification by small protein conjugation or removalGO:00706472070.012
innate immune responseGO:00450871570.012
intracellular protein transportGO:00068862040.012
nucleic acid phosphodiester bond hydrolysisGO:0090305490.012
Human
negative regulation of mitotic sister chromatid segregationGO:003304870.012
muscle cell differentiationGO:00426922610.011
negative regulation of meiotic cell cycle phase transitionGO:190199430.011
regulation of epithelial cell proliferationGO:00506781410.011
neural tube closureGO:0001843900.011
peptidyl serine modificationGO:0018209830.011
tube formationGO:00351481400.011
positive regulation of immune effector processGO:00026991070.011
locomotory behaviorGO:00076261950.011
dna integrity checkpointGO:0031570280.011
Human
centromere complex assemblyGO:003450830.011
embryonic placenta developmentGO:0001892980.011
negative regulation of mitotic metaphase anaphase transitionGO:004584170.011
regulation of cellular component sizeGO:00325351210.011
cellularizationGO:000734910.011
positive regulation of kinase activityGO:00336741550.011
retrograde transport endosome to golgiGO:004214720.011
embryonic organ morphogenesisGO:00485622760.011
peptidyl threonine modificationGO:0018210310.011
cellular chemical homeostasisGO:00550822150.011
g2 m transition of mitotic cell cycleGO:0000086200.011
pharynx developmentGO:006046510.011
positive regulation of transferase activityGO:00513471670.011
positive regulation of cellular component biogenesisGO:0044089940.011
regulation of endopeptidase activityGO:0052548890.011
protein localization to chromatinGO:007116830.011
epithelial tube morphogenesisGO:00605623030.011
apoptotic nuclear changesGO:003026290.011
hematopoietic progenitor cell differentiationGO:00022441430.011
positive regulation of histone modificationGO:0031058280.011
telomere maintenanceGO:0000723190.011
positive regulation of cytokine productionGO:00018191740.010
telencephalon developmentGO:00215371860.010
positive regulation of nucleoside metabolic processGO:0045979910.010
action potentialGO:0001508780.010
developmental maturationGO:00217001930.010
dna dependent dna replication maintenance of fidelityGO:004500530.010
cell growthGO:00160491300.010
regulation of response to woundingGO:19030341890.010
telomere maintenance via telomeraseGO:000700410.010
dna catabolic process exonucleolyticGO:000073830.010
Human
wound healingGO:00420601570.010
spindle assemblyGO:0051225130.010
negative regulation of proteolysisGO:0045861740.010
inflammatory responseGO:00069542440.010
morphogenesis of a branching epitheliumGO:00611381930.010
establishment of protein localization to organelleGO:00725941180.010

Dna2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.030
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.013
physical disorderDOID:008001500.012
hematopoietic system diseaseDOID:7400.011