Mus musculus

51 known processes

Spire2

spire homolog 2 (Drosophila)

(Aliases: MGC31610,Spir2,KIAA1832,BC026502,Spir-2)

Spire2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axon cargo transportGO:0008088330.210
microtubule based movementGO:0007018840.189
cellular amino acid metabolic processGO:00065201030.181
microtubule based transportGO:0010970500.158
male gamete generationGO:00482322850.129
synaptic vesicle localizationGO:0097479590.101
membrane organizationGO:00610242450.099
cellular component assembly involved in morphogenesisGO:00109271390.086
axonogenesisGO:00074092740.083
establishment of vesicle localizationGO:0051650810.079
vesicle localizationGO:0051648860.076
cytoskeleton dependent intracellular transportGO:0030705500.070
spermatogenesisGO:00072832840.067
ras protein signal transductionGO:0007265770.066
carbohydrate derivative catabolic processGO:19011362310.060
nucleoside phosphate metabolic processGO:00067533380.059
organelle assemblyGO:00709251770.059
purine nucleoside triphosphate metabolic processGO:00091442260.056
regulation of cell motilityGO:20001452360.056
exocytosisGO:00068871210.055
nucleotide metabolic processGO:00091173320.055
regulation of hormone levelsGO:00108172110.053
regulation of neuron differentiationGO:00456642810.053
microtubule based processGO:00070172360.052
purine nucleoside metabolic processGO:00422782410.052
glycosyl compound metabolic processGO:19016572460.052
cilium morphogenesisGO:00602711020.051
defecationGO:003042110.050
cellular amine metabolic processGO:0044106440.050
negative regulation of molecular functionGO:00440922580.049
dendrite developmentGO:00163581150.047
fertilizationGO:00095661270.045
organic cyclic compound catabolic processGO:19013612950.045
ribose phosphate metabolic processGO:00196932910.045
establishment of synaptic vesicle localizationGO:0097480570.044
positive regulation of necrotic cell deathGO:001094010.044
nucleobase containing small molecule metabolic processGO:00550863520.043
purine ribonucleoside catabolic processGO:00461302050.040
organelle localizationGO:00516401790.040
spermatid differentiationGO:00485151150.038
ion transmembrane transportGO:00342203610.038
intracellular protein transportGO:00068862040.038
synaptic vesicle transportGO:0048489570.037
cellular nitrogen compound catabolic processGO:00442702800.036
cellular ketone metabolic processGO:0042180840.036
axon transport of mitochondrionGO:001989620.035
response to oxidative stressGO:00069791230.035
purine nucleotide catabolic processGO:00061952110.034
microtubule cytoskeleton organizationGO:00002261570.034
purine ribonucleoside metabolic processGO:00461282410.034
purine ribonucleotide catabolic processGO:00091542080.034
carbohydrate metabolic processGO:00059752300.034
regulation of cellular amino acid metabolic processGO:000652150.033
nucleoside metabolic processGO:00091162460.033
ribonucleoside metabolic processGO:00091192450.033
actin cytoskeleton organizationGO:00300362200.033
peptidyl amino acid modificationGO:00181933360.033
nucleoside triphosphate metabolic processGO:00091412300.032
adult behaviorGO:00305341350.032
sensory perceptionGO:00076002450.032
dna metabolic processGO:00062593030.032
nucleoside triphosphate catabolic processGO:00091432050.032
protein modification by small protein conjugation or removalGO:00706472070.031
purine ribonucleoside triphosphate metabolic processGO:00092052200.031
organonitrogen compound catabolic processGO:19015652640.031
cation transportGO:00068123990.031
cellular response to organonitrogen compoundGO:00714171450.031
establishment of organelle localizationGO:00516561220.031
reactive oxygen species metabolic processGO:0072593840.030
regulation of cellular amine metabolic processGO:0033238200.029
nitrogen compound transportGO:00717052710.029
regulation of intracellular transportGO:00323861590.029
amine metabolic processGO:0009308450.028
intracellular mrna localizationGO:000829840.028
peptide transportGO:00158331330.028
purine nucleoside triphosphate catabolic processGO:00091462030.028
spermatid developmentGO:00072861080.027
compound eye developmentGO:004874910.027
ribonucleoside triphosphate metabolic processGO:00091992200.027
nucleoside catabolic processGO:00091642060.027
oocyte constructionGO:000730820.027
purine nucleotide metabolic processGO:00061633020.026
purine ribonucleotide metabolic processGO:00091502900.026
hindbrain developmentGO:00309021280.026
cellular homeostasisGO:00197252400.024
regulation of cellular ketone metabolic processGO:0010565660.024
establishment of mitochondrion localizationGO:005165440.024
endomembrane system organizationGO:00102561470.024
aromatic compound catabolic processGO:00194392860.024
purine nucleoside monophosphate metabolic processGO:0009126810.024
nucleoside phosphate catabolic processGO:19012922220.024
macromolecule catabolic processGO:00090572810.023
germ cell developmentGO:00072811850.023
purine containing compound metabolic processGO:00725213110.023
organophosphate catabolic processGO:00464342320.023
axon guidanceGO:00074111410.022
ribonucleoside catabolic processGO:00424542060.022
neuronal action potentialGO:0019228540.022
protein localization to organelleGO:00333651850.022
protein ubiquitinationGO:00165671710.022
gtp catabolic processGO:00061841430.022
ribonucleotide metabolic processGO:00092592910.022
positive regulation of protein modification processGO:00314012990.022
glycosyl compound catabolic processGO:19016582060.022
regulation of hydrolase activityGO:00513362460.022
neurotransmitter secretionGO:0007269620.022
glycerolipid metabolic processGO:00464861220.021
positive regulation of nervous system developmentGO:00519622210.021
cilium assemblyGO:0042384810.021
cellular carbohydrate metabolic processGO:00442621190.021
oocyte axis specificationGO:000730920.021
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.021
protein targetingGO:00066051430.021
small gtpase mediated signal transductionGO:0007264970.021
multicellular organismal signalingGO:0035637910.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
negative regulation of cellular component organizationGO:00511291940.020
cell adhesionGO:00071553290.020
guanosine containing compound metabolic processGO:19010681440.020
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.020
purine containing compound catabolic processGO:00725232130.020
cation transmembrane transportGO:00986552660.019
nucleotide catabolic processGO:00091662170.019
nuclear divisionGO:00002801580.019
protein modification by small protein conjugationGO:00324461870.019
regulation of receptor activityGO:0010469410.019
camera type eye developmentGO:00430102660.019
insulin secretionGO:0030073890.019
cellularizationGO:000734910.019
negative regulation of cell developmentGO:00107211690.019
meiotic cell cycle processGO:1903046770.019
meiotic cell cycleGO:00513211220.019
response to nutrient levelsGO:00316671090.019
cell junction maintenanceGO:003433140.019
cytoplasmic transportGO:00164822340.019
synapse organizationGO:00508081250.018
peptide secretionGO:00027901140.018
protein localization to membraneGO:00726571080.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
positive regulation of cell developmentGO:00107202370.018
modification dependent macromolecule catabolic processGO:00436321330.018
regulation of metal ion transportGO:00109591060.018
negative regulation of synapse assemblyGO:005196430.018
negative regulation of nervous system developmentGO:00519611560.018
developmental maturationGO:00217001930.018
inorganic ion transmembrane transportGO:00986602340.018
peptidyl serine modificationGO:0018209830.018
positive regulation of cell projection organizationGO:0031346950.017
divalent metal ion transportGO:00708381720.017
cellular protein catabolic processGO:00442571550.017
heterocycle catabolic processGO:00467002800.017
chemotaxisGO:00069352470.017
membrane lipid metabolic processGO:0006643530.017
organelle fissionGO:00482851700.016
ribonucleotide catabolic processGO:00092612080.016
positive regulation of neuron differentiationGO:00456661410.016
central nervous system neuron differentiationGO:00219531620.016
response to organonitrogen compoundGO:00102432460.016
regulation of synaptic plasticityGO:0048167870.016
transmission of nerve impulseGO:0019226760.016
regulation of feeding behaviorGO:006025930.016
urogenital system developmentGO:00016552610.016
regulation of cytoplasmic transportGO:19036491120.016
regulation of ras protein signal transductionGO:00465781140.016
regulation of cytoskeleton organizationGO:00514931220.015
peptidyl serine phosphorylationGO:0018105740.015
plasma membrane organizationGO:0007009900.015
negative regulation of neuron differentiationGO:00456651010.015
modification dependent protein catabolic processGO:00199411330.015
cellular response to hormone stimulusGO:00328701500.015
phospholipid metabolic processGO:0006644870.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
neurotransmitter transportGO:0006836760.015
vesicle organizationGO:0016050600.015
purine nucleoside catabolic processGO:00061522050.015
maintenance of locationGO:0051235890.015
locomotory behaviorGO:00076261950.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
calcium ion dependent exocytosisGO:0017156350.015
regulation of transmembrane transportGO:00347621280.015
negative regulation of intracellular signal transductionGO:19025321670.015
molting cycleGO:0042303900.014
dephosphorylationGO:00163111290.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
negative regulation of protein metabolic processGO:00512482820.014
regulation of cellular component sizeGO:00325351210.014
positive regulation of cellular amine metabolic processGO:003324050.014
divalent inorganic cation transportGO:00725111780.014
rna processingGO:00063961050.014
hormone secretionGO:00468791280.014
purine ribonucleoside monophosphate metabolic processGO:0009167800.014
calcium ion homeostasisGO:00550741270.014
cellular lipid metabolic processGO:00442553230.014
regulation of organelle organizationGO:00330432890.014
carbohydrate biosynthetic processGO:0016051740.014
sperm motilityGO:0030317470.013
cellular response to peptideGO:1901653920.013
adult locomotory behaviorGO:0008344910.013
regulation of membrane potentialGO:00423911920.013
negative regulation of cellular protein metabolic processGO:00322692470.013
single organismal cell cell adhesionGO:00163371310.013
extracellular structure organizationGO:00430621480.013
organonitrogen compound biosynthetic processGO:19015661920.013
guanosine containing compound catabolic processGO:19010691440.013
transition metal ion transportGO:0000041380.013
regulation of purine nucleotide metabolic processGO:19005421690.013
cellular modified amino acid metabolic processGO:0006575630.013
renal system developmentGO:00720012250.013
gliogenesisGO:00420631410.013
peptide hormone secretionGO:00300721090.013
transmembrane transportGO:00550854120.013
cell chemotaxisGO:0060326810.013
cellular response to dna damage stimulusGO:00069742070.012
rac protein signal transductionGO:0016601130.012
regulation of ion transmembrane transportGO:00347651190.012
establishment of protein localization to membraneGO:0090150540.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
cellular macromolecule catabolic processGO:00442652060.012
regulation of cell cycle processGO:00105641600.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
negative regulation of phosphate metabolic processGO:00459361840.012
mrna metabolic processGO:0016071840.012
lipid biosynthetic processGO:00086101790.012
regulation of cell projection organizationGO:00313442060.012
ubiquitin dependent protein catabolic processGO:00065111290.012
cerebellum morphogenesisGO:0021587420.012
nucleoside monophosphate metabolic processGO:0009123850.012
regulation of proteolysisGO:00301621640.012
development of primary sexual characteristicsGO:00451371430.012
atp metabolic processGO:0046034750.012
regulation of ion transportGO:00432692150.012
regionalizationGO:00030023370.012
positive regulation of protein phosphorylationGO:00019342420.012
protein catabolic processGO:00301632210.011
amide transportGO:00428861380.011
posttranscriptional regulation of gene expressionGO:00106081550.011
positive regulation of cell deathGO:00109422240.011
lateral inhibitionGO:004633110.011
inorganic cation transmembrane transportGO:00986622070.011
calcium ion transportGO:00068161590.011
negative regulation of phosphorylationGO:00423261660.011
cellular chemical homeostasisGO:00550822150.011
gtp metabolic processGO:00460391440.011
protein maturationGO:00516041760.011
regulation of protein catabolic processGO:00421761080.011
regulation of peptidase activityGO:0052547960.011
rho protein signal transductionGO:0007266320.011
maternal determination of anterior posterior axis embryoGO:000835820.011
negative regulation of protein modification processGO:00314001630.011
alcohol metabolic processGO:00060661160.011
nucleocytoplasmic transportGO:00069131390.011
rap protein signal transductionGO:003248630.011
regulation of neuron projection developmentGO:00109751690.011
regulation of microtubule based processGO:0032886520.011
mitotic cell cycleGO:00002781950.011
regulation of protein targetingGO:1903533610.011
cation homeostasisGO:00550802120.011
cellular protein complex assemblyGO:00436231160.010
positive regulation of neuron projection developmentGO:0010976790.010
reactive nitrogen species metabolic processGO:200105700.010
synapse assemblyGO:0007416560.010
response to extracellular stimulusGO:00099911270.010
regulation of apoptotic signaling pathwayGO:20012331970.010
neuromuscular processGO:0050905990.010
regulation of neurotransmitter levelsGO:0001505870.010
organic hydroxy compound metabolic processGO:19016152030.010
regulation of cell migrationGO:00303342190.010
regulation of protein kinase activityGO:00458592320.010
oxidation reduction processGO:00551143420.010
regulation of nucleocytoplasmic transportGO:0046822730.010
nuclear transportGO:00511691390.010
meiosis iGO:0007127600.010
male sex differentiationGO:00466611090.010
response to monosaccharideGO:0034284670.010

Spire2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
disease of cellular proliferationDOID:1456600.012
disease of metabolismDOID:001466700.011