Mus musculus

0 known processes

Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

(Aliases: MLC,WKL1,mKIAA0027,VL,AW048630,BB074274,Kiaa0027-hp,LVM)

Mlc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuronal action potentialGO:0019228540.096
anion transmembrane transportGO:0098656710.092
carboxylic acid transportGO:00469421000.090
ion transmembrane transportGO:00342203610.089
synaptic transmissionGO:00072683290.087
regulation of cellular amine metabolic processGO:0033238200.082
organic cyclic compound catabolic processGO:19013612950.077
cellular amino acid metabolic processGO:00065201030.076
action potentialGO:0001508780.069
organic anion transportGO:00157111370.068
amino acid transportGO:0006865610.064
aromatic compound catabolic processGO:00194392860.061
cellular ketone metabolic processGO:0042180840.058
regulation of cellular amino acid metabolic processGO:000652150.058
regulation of cellular ketone metabolic processGO:0010565660.056
cellular amine metabolic processGO:0044106440.055
cellular nitrogen compound catabolic processGO:00442702800.054
organonitrogen compound catabolic processGO:19015652640.054
positive regulation of cellular amine metabolic processGO:003324050.053
purine nucleotide metabolic processGO:00061633020.052
amino acid transmembrane transportGO:0003333370.051
myelinationGO:0042552740.050
transmission of nerve impulseGO:0019226760.050
organic acid transportGO:00158491010.050
nitrogen compound transportGO:00717052710.050
transmembrane transportGO:00550854120.049
carbohydrate derivative catabolic processGO:19011362310.048
purine ribonucleotide catabolic processGO:00091542080.048
purine nucleoside triphosphate metabolic processGO:00091442260.047
small gtpase mediated signal transductionGO:0007264970.047
positive regulation of cellular amino acid metabolic processGO:004576430.046
regulation of membrane potentialGO:00423911920.045
nucleotide catabolic processGO:00091662170.045
purine nucleoside metabolic processGO:00422782410.044
multicellular organismal signalingGO:0035637910.043
purine ribonucleotide metabolic processGO:00091502900.042
membrane organizationGO:00610242450.040
ensheathment of neuronsGO:0007272760.040
ribonucleoside catabolic processGO:00424542060.040
nucleoside phosphate metabolic processGO:00067533380.040
purine nucleoside triphosphate catabolic processGO:00091462030.040
purine containing compound catabolic processGO:00725232130.040
nucleoside triphosphate metabolic processGO:00091412300.038
purine ribonucleoside metabolic processGO:00461282410.038
heterocycle catabolic processGO:00467002800.038
nucleoside phosphate catabolic processGO:19012922220.038
ras protein signal transductionGO:0007265770.037
nucleotide metabolic processGO:00091173320.037
amine metabolic processGO:0009308450.037
purine ribonucleoside triphosphate catabolic processGO:00092071990.037
ribonucleoside metabolic processGO:00091192450.037
response to organonitrogen compoundGO:00102432460.037
glycosyl compound catabolic processGO:19016582060.036
nucleobase containing small molecule metabolic processGO:00550863520.036
regulation of ion transportGO:00432692150.036
ribonucleotide catabolic processGO:00092612080.034
l amino acid transportGO:0015807320.033
nucleoside triphosphate catabolic processGO:00091432050.032
nucleoside metabolic processGO:00091162460.032
cation transmembrane transportGO:00986552660.031
mapk cascadeGO:00001652810.031
purine ribonucleoside triphosphate metabolic processGO:00092052200.031
organophosphate catabolic processGO:00464342320.030
g protein coupled receptor signaling pathwayGO:00071862430.029
axon ensheathmentGO:0008366760.029
exocytosisGO:00068871210.029
cation transportGO:00068123990.029
ribonucleotide metabolic processGO:00092592910.029
purine nucleoside catabolic processGO:00061522050.029
monocarboxylic acid metabolic processGO:00327871910.028
ribonucleoside triphosphate catabolic processGO:00092031990.028
ribose phosphate metabolic processGO:00196932910.028
cytoplasmic transportGO:00164822340.028
lipid biosynthetic processGO:00086101790.028
organelle fissionGO:00482851700.028
muscle cell differentiationGO:00426922610.028
regulation of gtp catabolic processGO:00331241130.028
positive regulation of cell developmentGO:00107202370.027
glycosyl compound metabolic processGO:19016572460.027
cell adhesionGO:00071553290.026
carbohydrate derivative biosynthetic processGO:19011371830.026
response to acid chemicalGO:00011011110.026
purine nucleotide catabolic processGO:00061952110.026
regulation of establishment of protein localizationGO:00702011810.026
cellular lipid metabolic processGO:00442553230.026
negative regulation of cell proliferationGO:00082852960.025
muscle system processGO:00030121410.025
macromolecule catabolic processGO:00090572810.025
regulation of mapk cascadeGO:00434082480.023
inorganic cation transmembrane transportGO:00986622070.023
regulation of transferase activityGO:00513382630.023
glycoprotein metabolic processGO:00091001160.023
intracellular protein transportGO:00068862040.022
positive regulation of transferase activityGO:00513471670.022
response to extracellular stimulusGO:00099911270.022
regulation of cellular catabolic processGO:00313292420.022
cytokine productionGO:00018163190.022
regulation of cell activationGO:00508652890.021
anion transportGO:00068201770.021
nucleoside catabolic processGO:00091642060.021
organic hydroxy compound metabolic processGO:19016152030.021
regulation of protein kinase activityGO:00458592320.021
regulation of purine nucleotide metabolic processGO:19005421690.021
regulation of protein serine threonine kinase activityGO:00719001570.020
sodium ion transmembrane transportGO:0035725490.020
response to organic cyclic compoundGO:00140701980.020
positive regulation of protein phosphorylationGO:00019342420.020
peptidyl amino acid modificationGO:00181933360.020
gtp catabolic processGO:00061841430.020
ventricular cardiac muscle cell action potentialGO:008600540.020
regulation of protein localizationGO:00328802310.020
muscle tissue developmentGO:00605373080.020
purine ribonucleoside catabolic processGO:00461302050.020
guanosine containing compound catabolic processGO:19010691440.020
purine containing compound metabolic processGO:00725213110.020
cellular response to lipidGO:00713961450.020
c4 dicarboxylate transportGO:001574030.020
regulation of nucleotide metabolic processGO:00061401690.020
cardiac muscle contractionGO:0060048320.020
monosaccharide transportGO:0015749580.020
glycoprotein biosynthetic processGO:0009101890.020
regulation of nucleoside metabolic processGO:00091181300.019
regulation of kinase activityGO:00435492490.019
response to nutrient levelsGO:00316671090.019
regulation of nucleotide catabolic processGO:00308111220.019
regulation of neuron differentiationGO:00456642810.019
positive regulation of nervous system developmentGO:00519622210.019
muscle contractionGO:00069361010.019
negative regulation of phosphorus metabolic processGO:00105631840.018
sodium ion transportGO:0006814730.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
phospholipase c activating serotonin receptor signaling pathwayGO:000720810.018
actin filament based movementGO:0030048230.018
peptidyl tyrosine modificationGO:00182121450.018
skeletal system developmentGO:00015013560.018
regulation of secretionGO:00510462740.017
cellular chemical homeostasisGO:00550822150.017
regulation of intracellular transportGO:00323861590.017
positive regulation of cellular catabolic processGO:00313311480.017
positive regulation of protein modification processGO:00314012990.017
protein localization to organelleGO:00333651850.017
response to light stimulusGO:00094161350.017
immune effector processGO:00022523210.017
regulation of cellular component biogenesisGO:00440871810.017
regulation of anatomical structure sizeGO:00900661780.017
carbohydrate metabolic processGO:00059752300.017
regulation of cell projection organizationGO:00313442060.017
peptidyl tyrosine phosphorylationGO:00181081430.017
organic hydroxy compound transportGO:0015850930.016
sensory perceptionGO:00076002450.016
protein localization to membraneGO:00726571080.016
nuclear divisionGO:00002801580.016
neuron neuron synaptic transmissionGO:0007270690.016
regulation of purine nucleotide catabolic processGO:00331211220.016
cell substrate adhesionGO:00315891300.016
rho protein signal transductionGO:0007266320.016
regulation of cell cycleGO:00517262810.016
negative regulation of molecular functionGO:00440922580.016
maternal determination of anterior posterior axis embryoGO:000835820.016
l alpha amino acid transmembrane transportGO:1902475230.016
regulation of cellular response to stressGO:00801351590.016
cardiac muscle cell contractionGO:008600370.016
lymphocyte differentiationGO:00300982420.016
av node cell to bundle of his cell communicationGO:008606720.016
cellular homeostasisGO:00197252400.015
telencephalon developmentGO:00215371860.015
negative regulation of protein metabolic processGO:00512482820.015
sulfur compound metabolic processGO:00067901000.015
oocyte anterior posterior axis specificationGO:000731420.015
regulation of postsynaptic membrane potentialGO:0060078480.015
actin mediated cell contractionGO:0070252150.015
myotube differentiationGO:00149021050.015
fat cell differentiationGO:00454441600.015
germ cell developmentGO:00072811850.015
negative regulation of cellular protein metabolic processGO:00322692470.015
response to retinoic acidGO:0032526560.015
oocyte constructionGO:000730820.015
meiotic cell cycleGO:00513211220.015
microtubule based processGO:00070172360.015
regulation of vesicle mediated transportGO:00606271390.015
protein targetingGO:00066051430.015
protein catabolic processGO:00301632210.015
male gamete generationGO:00482322850.015
single organism nuclear importGO:1902593950.015
camera type eye developmentGO:00430102660.015
oocyte axis specificationGO:000730920.015
guanosine containing compound metabolic processGO:19010681440.015
regulation of apoptotic signaling pathwayGO:20012331970.015
inorganic ion transmembrane transportGO:00986602340.015
endocytosisGO:00068971680.014
oxidation reduction processGO:00551143420.014
regulation of tissue remodelingGO:0034103380.014
positive regulation of protein transportGO:0051222930.014
cellular response to hormone stimulusGO:00328701500.014
negative regulation of protein kinase activity by regulation of protein phosphorylationGO:004438720.014
mesodermal cell migrationGO:000807840.014
intracellular mrna localizationGO:000829840.014
regulation of neuron apoptotic processGO:00435231220.014
regulation of blood circulationGO:1903522930.014
regulation of cell migrationGO:00303342190.014
protein modification by small protein conjugation or removalGO:00706472070.014
multicellular organism growthGO:00352641610.014
regulation of ventricular cardiac muscle cell membrane depolarizationGO:006037320.014
regulation of hormone levelsGO:00108172110.014
positive regulation of nucleoside metabolic processGO:0045979910.014
posttranscriptional regulation of gene expressionGO:00106081550.014
glycerolipid metabolic processGO:00464861220.014
regulation of neurotransmitter levelsGO:0001505870.014
midgut developmentGO:000749440.014
milk ejectionGO:006015610.014
neuron deathGO:00709971540.014
cellular response to acid chemicalGO:0071229680.013
meiotic nuclear divisionGO:00071261150.013
sa node cell action potentialGO:008601540.013
pole plasm assemblyGO:000731520.013
regulation of lymphocyte activationGO:00512492400.013
cytokine secretionGO:0050663720.013
regulation of ras protein signal transductionGO:00465781140.013
gtp metabolic processGO:00460391440.013
synapse organizationGO:00508081250.013
positive regulation of mapk cascadeGO:00434101700.013
establishment or maintenance of cytoskeleton polarityGO:003095220.013
adult behaviorGO:00305341350.013
nuclear transportGO:00511691390.013
cellular response to organonitrogen compoundGO:00714171450.013
cellular macromolecule catabolic processGO:00442652060.013
epithelial cell proliferation involved in prostatic bud elongationGO:006051710.013
nucleocytoplasmic transportGO:00069131390.013
neurotransmitter transportGO:0006836760.013
positive regulation of gtp catabolic processGO:0033126850.013
positive regulation of purine nucleotide catabolic processGO:0033123880.013
dicarboxylic acid transportGO:0006835290.013
neuron apoptotic processGO:00514021420.013
regulation of protein transportGO:00512231630.013
adult locomotory behaviorGO:0008344910.013
positive regulation of kinase activityGO:00336741550.013
amide transportGO:00428861380.013
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
interleukin 8 secretionGO:007260630.012
negative regulation of neuron differentiationGO:00456651010.012
regulation of transmembrane transportGO:00347621280.012
mitochondrion organizationGO:00070051340.012
negative regulation of membrane potentialGO:004583740.012
regulation of ras gtpase activityGO:0032318880.012
establishment of protein localization to organelleGO:00725941180.012
positive regulation of ras gtpase activityGO:0032320650.012
regulation of protein processingGO:0070613960.012
rac protein signal transductionGO:0016601130.012
mitotic cytokinesisGO:000028140.012
positive regulation of nucleotide catabolic processGO:0030813880.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
regulation of cell adhesionGO:00301551540.012
positive regulation of gtpase activityGO:0043547850.012
circulatory system processGO:00030131970.012
retina development in camera type eyeGO:00600411190.012
cellular response to organic cyclic compoundGO:0071407870.012
acid secretionGO:0046717330.012
response to oxidative stressGO:00069791230.012
carbohydrate transportGO:0008643620.012
organonitrogen compound biosynthetic processGO:19015661920.012
regulation of secretion by cellGO:19035302490.012
negative regulation of cellular component organizationGO:00511291940.012
maintenance of locationGO:0051235890.012
spermatogenesisGO:00072832840.012
cellular response to external stimulusGO:0071496880.012
inorganic anion transmembrane transportGO:0098661290.012
regulation of muscle contractionGO:0006937490.012
membrane lipid biosynthetic processGO:0046467320.012
regulation of fat cell differentiationGO:0045598810.012
microtubule cytoskeleton organizationGO:00002261570.012
mitotic cell cycleGO:00002781950.012
rna interferenceGO:001624620.012
establishment of blood nerve barrierGO:000806530.012
peptidyl serine modificationGO:0018209830.012
rap protein signal transductionGO:003248630.012
vascular process in circulatory systemGO:0003018620.012
positive regulation of protein kinase activityGO:00458601440.012
protein secretionGO:00093061110.011
regulation of ion homeostasisGO:2000021640.011
cognitionGO:00508901490.011
multi multicellular organism processGO:00447061090.011
blood vessel morphogenesisGO:00485142850.011
sequestering of metal ionGO:0051238190.011
atrial ventricular junction remodelingGO:000329420.011
organelle localizationGO:00516401790.011
tissue homeostasisGO:00018941150.011
regulation of cytokine productionGO:00018172660.011
glycerolipid biosynthetic processGO:0045017500.011
cellular response to oxidative stressGO:0034599760.011
sensory perception of mechanical stimulusGO:00509541070.011
vesicle organizationGO:0016050600.011
forebrain developmentGO:00309003020.011
regulation of hydrolase activityGO:00513362460.011
carbohydrate homeostasisGO:00335001280.011
innate immune responseGO:00450871570.011
regulation of renin secretion into blood streamGO:190013340.011
central nervous system neuron differentiationGO:00219531620.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
response to molecule of bacterial originGO:00022371430.011
canonical wnt signaling pathwayGO:00600701300.011
negative regulation of growthGO:0045926990.011
negative regulation of cell developmentGO:00107211690.011
hematopoietic progenitor cell differentiationGO:00022441430.011
regulation of map kinase activityGO:00434051200.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
engulfment of apoptotic cellGO:004365230.011
cation homeostasisGO:00550802120.011
sphingolipid biosynthetic processGO:0030148260.011
regulation of bone remodelingGO:0046850280.011
regulation of mitotic cell cycleGO:00073461260.011
response to radiationGO:00093141650.011
interleukin 8 productionGO:003263740.011
glutamate biosynthetic processGO:000653720.011
myeloid cell differentiationGO:00300992330.011
t cell activationGO:00421102890.011
regulation of organelle organizationGO:00330432890.010
negative regulation of phosphorylationGO:00423261660.010
negative regulation of phagocytosisGO:005076540.010
bone resorptionGO:0045453380.010
dna metabolic processGO:00062593030.010
establishment of protein localization to vacuoleGO:007266640.010
photoreceptor cell differentiationGO:0046530520.010
d amino acid transportGO:004294010.010
response to drugGO:0042493750.010
t cell differentiationGO:00302171740.010
photoreceptor cell morphogenesisGO:000859430.010
positive regulation of secretion by cellGO:19035321140.010
foramen ovale closureGO:003592210.010
regulation of ion transmembrane transporter activityGO:0032412540.010
positive regulation of cell projection organizationGO:0031346950.010
negative regulation of phosphate metabolic processGO:00459361840.010
response to lipopolysaccharideGO:00324961280.010
sphingosine 1 phosphate signaling pathwayGO:000337630.010
protein oligomerizationGO:0051259670.010
regulation of protein maturationGO:1903317960.010

Mlc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
central nervous system diseaseDOID:33100.025
neuropathyDOID:87000.013
neuromuscular diseaseDOID:44000.013
neurodegenerative diseaseDOID:128900.012
sensory system diseaseDOID:005015500.011