| negative regulation of molecular function | GO:0044092 | 258 | 0.088 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.069 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.062 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.059 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.053 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.050 | |
| endocytosis | GO:0006897 | 168 | 0.047 | |
| amine metabolic process | GO:0009308 | 45 | 0.046 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.046 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.045 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.045 | |
| protein polymerization | GO:0051258 | 57 | 0.044 | |
| cation transport | GO:0006812 | 399 | 0.043 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.041 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.039 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.038 | |
| cell adhesion | GO:0007155 | 329 | 0.038 | |
| transmembrane transport | GO:0055085 | 412 | 0.037 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.036 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.036 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.035 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.032 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.031 | |
| actin filament polymerization | GO:0030041 | 44 | 0.031 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.031 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.031 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.030 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.030 | |
| regulation of ion transport | GO:0043269 | 215 | 0.029 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.029 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.029 | |
| regulation of cell activation | GO:0050865 | 289 | 0.029 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.029 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.028 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.028 | |
| lytic vacuole organization | GO:0080171 | 21 | 0.028 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.028 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.028 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.028 | |
| golgi to endosome transport | GO:0006895 | 3 | 0.028 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.028 | |
| myosin filament organization | GO:0031033 | 3 | 0.027 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.027 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.027 | |
| synaptic transmission | GO:0007268 | 329 | 0.027 | |
| protein maturation | GO:0051604 | 176 | 0.027 | |
| oxidation reduction process | GO:0055114 | 342 | 0.027 | |
| cellular homeostasis | GO:0019725 | 240 | 0.027 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.027 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.026 | |
| cation homeostasis | GO:0055080 | 212 | 0.026 | |
| regulation of neuron death | GO:1901214 | 134 | 0.026 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.026 | |
| organelle assembly | GO:0070925 | 177 | 0.026 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.025 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.025 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.025 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.025 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.025 | |
| spermatogenesis | GO:0007283 | 284 | 0.025 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.025 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.025 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.024 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.024 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.023 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.023 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.022 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.022 | |
| vesicle localization | GO:0051648 | 86 | 0.022 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.021 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.021 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.021 | |
| male gamete generation | GO:0048232 | 285 | 0.021 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.021 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.021 | |
| response to growth factor | GO:0070848 | 198 | 0.021 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.021 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.021 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.021 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.021 | |
| maintenance of location | GO:0051235 | 89 | 0.020 | |
| protein catabolic process | GO:0030163 | 221 | 0.020 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.020 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.020 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.020 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.020 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.020 | |
| arp2 3 complex mediated actin nucleation | GO:0034314 | 3 | 0.020 | |
| response to radiation | GO:0009314 | 165 | 0.020 | |
| organelle localization | GO:0051640 | 179 | 0.020 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.020 | |
| membrane organization | GO:0061024 | 245 | 0.020 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.020 | |
| blood circulation | GO:0008015 | 195 | 0.019 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.019 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.019 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.019 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.019 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.019 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.019 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.019 | |
| lysosome organization | GO:0007040 | 21 | 0.019 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.019 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.018 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.018 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.018 | |
| hormone secretion | GO:0046879 | 128 | 0.018 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.018 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.018 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.018 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.018 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.018 | |
| inflammatory response | GO:0006954 | 244 | 0.018 | |
| heart process | GO:0003015 | 94 | 0.018 | |
| cytosolic calcium ion transport | GO:0060401 | 48 | 0.017 | |
| regulation of protein processing | GO:0070613 | 96 | 0.017 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.017 | |
| synapse organization | GO:0050808 | 125 | 0.017 | |
| protein localization to membrane | GO:0072657 | 108 | 0.017 | |
| dephosphorylation | GO:0016311 | 129 | 0.017 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.017 | |
| cellular response to cadmium ion | GO:0071276 | 3 | 0.017 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.017 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.017 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.017 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.017 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.017 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.017 | |
| tissue homeostasis | GO:0001894 | 115 | 0.017 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.016 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.016 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.016 | |
| cell growth | GO:0016049 | 130 | 0.016 | |
| adult behavior | GO:0030534 | 135 | 0.016 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.016 | |
| protein processing | GO:0016485 | 163 | 0.016 | |
| regulation of binding | GO:0051098 | 111 | 0.016 | |
| calcium ion transport into cytosol | GO:0060402 | 48 | 0.016 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.016 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.016 | |
| axonogenesis | GO:0007409 | 274 | 0.016 | |
| skeletal system development | GO:0001501 | 356 | 0.016 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.015 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.015 | |
| neuron death | GO:0070997 | 154 | 0.015 | |
| peptide secretion | GO:0002790 | 114 | 0.015 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.015 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.015 | |
| regulation of arp2 3 complex mediated actin nucleation | GO:0034315 | 1 | 0.015 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.015 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.015 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.014 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.014 | |
| actin filament organization | GO:0007015 | 113 | 0.014 | |
| muscle tissue development | GO:0060537 | 308 | 0.014 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.014 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.014 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.014 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.014 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.014 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.014 | |
| peptide hormone secretion | GO:0030072 | 109 | 0.014 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.014 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.014 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.014 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.014 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.014 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.014 | |
| t cell proliferation | GO:0042098 | 120 | 0.014 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.014 | |
| epidermis development | GO:0008544 | 187 | 0.014 | |
| regulation of lamellipodium assembly | GO:0010591 | 3 | 0.014 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.014 | |
| vesicle organization | GO:0016050 | 60 | 0.014 | |
| regulation of protein localization | GO:0032880 | 231 | 0.014 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.013 | |
| synaptic vesicle transport | GO:0048489 | 57 | 0.013 | |
| regulation of actin nucleation | GO:0051125 | 4 | 0.013 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.013 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.013 | |
| negative regulation of kinase activity | GO:0033673 | 81 | 0.013 | |
| regulation of clathrin mediated endocytosis | GO:2000369 | 4 | 0.013 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.013 | |
| germ cell development | GO:0007281 | 185 | 0.013 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.013 | |
| adult locomotory behavior | GO:0008344 | 91 | 0.013 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.013 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 70 | 0.013 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.013 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.013 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.013 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.013 | |
| rac protein signal transduction | GO:0016601 | 13 | 0.013 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.013 | |
| cognition | GO:0050890 | 149 | 0.012 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.012 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.012 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.012 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.012 | |
| t cell activation | GO:0042110 | 289 | 0.012 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.012 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.012 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.012 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 49 | 0.012 | |
| regulation of protein binding | GO:0043393 | 60 | 0.012 | |
| organelle fission | GO:0048285 | 170 | 0.012 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.012 | |
| cell matrix adhesion | GO:0007160 | 68 | 0.012 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.012 | |
| response to inorganic substance | GO:0010035 | 96 | 0.012 | |
| monosaccharide transport | GO:0015749 | 58 | 0.012 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.012 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.012 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.011 | |
| cell substrate adhesion | GO:0031589 | 130 | 0.011 | |
| establishment of synaptic vesicle localization | GO:0097480 | 57 | 0.011 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.011 | |
| skin development | GO:0043588 | 220 | 0.011 | |
| intracellular protein transport | GO:0006886 | 204 | 0.011 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.011 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.011 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.011 | |
| calcium ion transport | GO:0006816 | 159 | 0.011 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.011 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.011 | |
| locomotory behavior | GO:0007626 | 195 | 0.011 | |
| membrane lipid metabolic process | GO:0006643 | 53 | 0.011 | |
| negative regulation of homeostatic process | GO:0032845 | 71 | 0.011 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.011 | |
| positive regulation of cardiac muscle contraction | GO:0060452 | 2 | 0.011 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.011 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.011 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.011 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.011 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.011 | |
| amide transport | GO:0042886 | 138 | 0.011 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.011 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.011 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.011 | |
| fat cell differentiation | GO:0045444 | 160 | 0.011 | |
| protein oligomerization | GO:0051259 | 67 | 0.011 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.011 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.011 | |
| circulatory system process | GO:0003013 | 197 | 0.011 | |
| response to nutrient levels | GO:0031667 | 109 | 0.011 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.011 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.011 | |
| regulation of heart contraction | GO:0008016 | 77 | 0.011 | |
| cellular response to arsenic containing substance | GO:0071243 | 4 | 0.011 | |
| sphingolipid metabolic process | GO:0006665 | 45 | 0.011 | |
| response to iron ion | GO:0010039 | 4 | 0.011 | |
| protein targeting | GO:0006605 | 143 | 0.010 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.010 | |
| microtubule based process | GO:0007017 | 236 | 0.010 | |
| sensory perception | GO:0007600 | 245 | 0.010 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.010 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 65 | 0.010 | |
| camera type eye development | GO:0043010 | 266 | 0.010 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.010 | |
| protein localization to organelle | GO:0033365 | 185 | 0.010 | |
| phagocytosis | GO:0006909 | 66 | 0.010 | |
| central nervous system neuron differentiation | GO:0021953 | 162 | 0.010 | |
| peptide transport | GO:0015833 | 133 | 0.010 | |
| mapk cascade | GO:0000165 | 281 | 0.010 | |
| regulation of cell growth | GO:0001558 | 91 | 0.010 | |
| b cell activation | GO:0042113 | 161 | 0.010 | |
| phagosome maturation | GO:0090382 | 4 | 0.010 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 45 | 0.010 | |
| feeding behavior | GO:0007631 | 62 | 0.010 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.010 | |
