Mus musculus

0 known processes

Pole2

polymerase (DNA directed), epsilon 2 (p59 subunit)

Pole2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synapsisGO:0007129340.701
dna metabolic processGO:00062593030.688
meiotic cell cycle processGO:1903046770.656
dna replicationGO:0006260520.627
cellular response to dna damage stimulusGO:00069742070.609
dna dependent dna replicationGO:0006261240.426
dna repairGO:00062811070.413
microtubule cytoskeleton organizationGO:00002261570.410
organic cyclic compound catabolic processGO:19013612950.356
meiosis iGO:0007127600.356
meiotic nuclear divisionGO:00071261150.340
organelle fissionGO:00482851700.332
dna endoreduplicationGO:004202340.307
meiotic cell cycleGO:00513211220.254
chromosome segregationGO:0007059480.253
heterocycle catabolic processGO:00467002800.246
dna conformation changeGO:0071103370.244
macromolecule catabolic processGO:00090572810.243
cellular nitrogen compound catabolic processGO:00442702800.226
cellular macromolecule catabolic processGO:00442652060.223
nuclear dna replicationGO:003326030.222
chromosome organization involved in meiosisGO:0070192390.213
dna recombinationGO:0006310920.207
double strand break repairGO:0006302480.199
nuclear divisionGO:00002801580.198
recombinational repairGO:0000725210.191
double strand break repair via homologous recombinationGO:0000724210.182
regulation of cell cycle processGO:00105641600.173
regulation of dna dependent dna replicationGO:009032980.169
mitotic centrosome separationGO:000710040.166
mitotic cell cycle processGO:19030471590.166
regulation of dna replicationGO:0006275170.163
chromatin organizationGO:00063252060.160
microtubule cytoskeleton organization involved in mitosisGO:190285040.158
mitotic cell cycleGO:00002781950.156
purine nucleoside catabolic processGO:00061522050.156
regulation of cell cycleGO:00517262810.144
synaptonemal complex assemblyGO:0007130130.135
microtubule based processGO:00070172360.132
purine ribonucleotide metabolic processGO:00091502900.117
organelle assemblyGO:00709251770.112
negative regulation of cell cycleGO:00457861230.108
purine nucleoside triphosphate metabolic processGO:00091442260.104
intra s dna damage checkpointGO:003157340.103
purine nucleotide metabolic processGO:00061633020.102
sister chromatid cohesionGO:0007062120.102
spindle assembly involved in mitosisGO:009030740.101
aromatic compound catabolic processGO:00194392860.101
regulation of mitotic cell cycleGO:00073461260.096
cell divisionGO:00513011200.096
nucleoside phosphate metabolic processGO:00067533380.093
negative regulation of cell cycle processGO:0010948690.093
nucleic acid phosphodiester bond hydrolysisGO:0090305490.091
negative regulation of mitotic cell cycle phase transitionGO:1901991450.091
nucleoside metabolic processGO:00091162460.090
female meiosis chromosome segregationGO:001632110.086
positive regulation of cell cycleGO:0045787920.086
nucleoside triphosphate metabolic processGO:00091412300.084
glycosyl compound catabolic processGO:19016582060.083
histone threonine phosphorylationGO:003540510.080
nucleobase containing small molecule metabolic processGO:00550863520.078
reciprocal dna recombinationGO:0035825160.077
purine nucleoside triphosphate catabolic processGO:00091462030.076
organonitrogen compound catabolic processGO:19015652640.075
ribose phosphate metabolic processGO:00196932910.075
dna packagingGO:0006323300.075
nucleoside phosphate catabolic processGO:19012922220.073
ribonucleoside catabolic processGO:00424542060.072
ribonucleotide catabolic processGO:00092612080.070
regulation of organelle organizationGO:00330432890.069
carbohydrate derivative catabolic processGO:19011362310.069
male meiosisGO:0007140370.068
translesion synthesisGO:001998510.068
covalent chromatin modificationGO:00165691630.068
mitotic cytokinesisGO:000028140.065
mitotic nuclear divisionGO:0007067480.063
purine containing compound catabolic processGO:00725232130.062
cellular protein catabolic processGO:00442571550.060
cell cycle checkpointGO:0000075470.059
purine nucleoside metabolic processGO:00422782410.057
reciprocal meiotic recombinationGO:0007131160.057
purine ribonucleoside metabolic processGO:00461282410.057
double strand break repair via nonhomologous end joiningGO:0006303100.057
cellular ketone metabolic processGO:0042180840.056
regulation of cellular catabolic processGO:00313292420.056
ribonucleoside metabolic processGO:00091192450.055
purine ribonucleoside triphosphate catabolic processGO:00092071990.055
chromatin modificationGO:00165681870.054
negative regulation of cell cycle phase transitionGO:1901988480.053
spermatogenesisGO:00072832840.053
ribonucleotide metabolic processGO:00092592910.052
peptidyl amino acid modificationGO:00181933360.052
glycosyl compound metabolic processGO:19016572460.052
regulation of cell cycle phase transitionGO:1901987770.051
nucleoside monophosphate metabolic processGO:0009123850.051
organophosphate catabolic processGO:00464342320.050
purine containing compound metabolic processGO:00725213110.050
negative regulation of mitotic cell cycleGO:0045930580.048
gene silencingGO:0016458380.046
nucleotide metabolic processGO:00091173320.046
regulation of cell divisionGO:0051302760.046
ribonucleoside triphosphate catabolic processGO:00092031990.045
regulation of cellular ketone metabolic processGO:0010565660.045
nucleoside triphosphate catabolic processGO:00091432050.044
regulation of nuclear cell cycle dna replicationGO:003326220.043
endocytosisGO:00068971680.042
dna integrity checkpointGO:0031570280.042
purine nucleotide catabolic processGO:00061952110.042
purine ribonucleotide catabolic processGO:00091542080.041
ribonucleoside triphosphate metabolic processGO:00091992200.041
dna dependent dna replication maintenance of fidelityGO:004500530.041
purine ribonucleoside triphosphate metabolic processGO:00092052200.041
regulation of cellular amino acid metabolic processGO:000652150.040
nucleoside catabolic processGO:00091642060.040
amine metabolic processGO:0009308450.039
dna replication independent nucleosome assemblyGO:000633610.039
female meiotic divisionGO:0007143210.039
mitotic sister chromatid segregationGO:0000070140.038
histone modificationGO:00165701590.038
development of primary sexual characteristicsGO:00451371430.038
Worm
cytokinetic processGO:003250620.038
dna catabolic process exonucleolyticGO:000073830.037
nuclear transportGO:00511691390.037
nucleotide catabolic processGO:00091662170.036
dna catabolic processGO:0006308190.036
establishment of organelle localizationGO:00516561220.035
protein catabolic processGO:00301632210.034
response to organic cyclic compoundGO:00140701980.033
cellular amino acid metabolic processGO:00065201030.033
organelle localizationGO:00516401790.033
regulation of cellular amine metabolic processGO:0033238200.032
meiotic chromosome segregationGO:0045132190.032
dephosphorylationGO:00163111290.032
regulation of kinase activityGO:00435492490.032
dna catabolic process endonucleolyticGO:0000737150.032
purine ribonucleoside catabolic processGO:00461302050.030
regulation of protein localizationGO:00328802310.030
regulation of mitotic cell cycle phase transitionGO:1901990730.030
negative regulation of phosphate metabolic processGO:00459361840.030
apoptotic signaling pathwayGO:00971903060.029
regulation of cytoskeleton organizationGO:00514931220.029
mitotic sister chromatid cohesionGO:000706410.029
fertilizationGO:00095661270.027
dna geometric changeGO:003239270.027
regulation of microtubule based processGO:0032886520.027
synaptonemal complex organizationGO:0070193150.027
muscle cell differentiationGO:00426922610.027
mitotic chromosome condensationGO:000707610.026
regulation of transferase activityGO:00513382630.026
histone phosphorylationGO:001657290.026
small gtpase mediated signal transductionGO:0007264970.026
intrinsic apoptotic signaling pathwayGO:00971931320.026
gonad developmentGO:00084061410.025
Worm
response to organonitrogen compoundGO:00102432460.025
microtubule organizing center organizationGO:0031023280.025
cellular amine metabolic processGO:0044106440.025
positive regulation of hydrolase activityGO:00513451480.025
regulation of hydrolase activityGO:00513362460.024
positive regulation of protein modification processGO:00314012990.024
spindle organizationGO:0007051280.024
regulation of establishment of protein localizationGO:00702011810.024
centrosome cycleGO:0007098230.024
purine nucleoside monophosphate metabolic processGO:0009126810.024
membrane organizationGO:00610242450.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
response to inorganic substanceGO:0010035960.023
positive regulation of cellular catabolic processGO:00313311480.023
oxidation reduction processGO:00551143420.023
positive regulation of purine nucleotide catabolic processGO:0033123880.023
cell cycle g1 s phase transitionGO:0044843570.023
protein dna complex subunit organizationGO:0071824280.022
atp metabolic processGO:0046034750.022
nucleocytoplasmic transportGO:00069131390.022
atp catabolic processGO:0006200550.022
positive regulation of cellular amine metabolic processGO:003324050.022
cell cycle comprising mitosis without cytokinesisGO:003330110.022
maintenance of locationGO:0051235890.021
cellular response to organonitrogen compoundGO:00714171450.021
purine ribonucleoside monophosphate catabolic processGO:0009169570.021
germ cell developmentGO:00072811850.021
negative regulation of cellular component organizationGO:00511291940.021
positive regulation of organelle organizationGO:00106381280.021
mitotic cell cycle checkpointGO:0007093310.020
ribonucleoside monophosphate catabolic processGO:0009158570.020
male gamete generationGO:00482322850.020
response to uvGO:0009411440.020
regulation of microtubule cytoskeleton organizationGO:0070507370.020
purine ribonucleoside monophosphate metabolic processGO:0009167800.020
dna biosynthetic processGO:0071897220.019
protein secretionGO:00093061110.019
ras protein signal transductionGO:0007265770.019
regulation of cytoplasmic transportGO:19036491120.018
regulation of cell motilityGO:20001452360.018
microtubule based movementGO:0007018840.018
mitochondrion organizationGO:00070051340.018
cell type specific apoptotic processGO:00972852680.018
single fertilizationGO:0007338820.018
neuron migrationGO:00017641220.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
spindle assemblyGO:0051225130.018
asymmetric stem cell divisionGO:009872230.018
dna replication initiationGO:000627050.018
mapk cascadeGO:00001652810.017
protein importGO:00170381010.017
receptor mediated endocytosisGO:0006898510.017
cellular lipid metabolic processGO:00442553230.017
intracellular protein transportGO:00068862040.017
positive regulation of kinase activityGO:00336741550.017
striated muscle myosin thick filament assemblyGO:007168810.017
cell fate commitmentGO:00451652100.017
positive regulation of programmed cell deathGO:00430682180.017
cellular response to organic cyclic compoundGO:0071407870.017
positive regulation of protein phosphorylationGO:00019342420.017
mrna processingGO:0006397630.017
male meiosis iGO:0007141160.017
response to light stimulusGO:00094161350.017
purine nucleoside monophosphate catabolic processGO:0009128580.017
negative regulation of dna replicationGO:000815640.017
regulation of mitosisGO:0007088290.017
positive regulation of cell deathGO:00109422240.016
centrosome separationGO:005129940.016
chromosome separationGO:0051304140.016
cellular response to abiotic stimulusGO:0071214560.016
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.016
cation transportGO:00068123990.016
regulation of response to woundingGO:19030341890.016
regulation of nucleoside metabolic processGO:00091181300.016
nucleoside monophosphate catabolic processGO:0009125590.016
rna processingGO:00063961050.016
centrosome organizationGO:0051297260.016
regulation of histone modificationGO:0031056560.016
ribonucleoside monophosphate metabolic processGO:0009161800.015
positive regulation of meiotic cell cycleGO:0051446150.015
dendrite developmentGO:00163581150.015
striated muscle cell developmentGO:00550021250.015
cellular response to lipidGO:00713961450.015
metaphase plate congressionGO:005131020.015
negative regulation of organelle organizationGO:0010639900.015
cell adhesionGO:00071553290.015
endomembrane system organizationGO:00102561470.015
regulation of cell migrationGO:00303342190.015
citrate metabolic processGO:000610130.015
regulation of protein transportGO:00512231630.014
posttranscriptional regulation of gene expressionGO:00106081550.014
regulation of chromosome organizationGO:0033044830.014
cellularizationGO:000734910.014
peptidyl serine modificationGO:0018209830.014
gland developmentGO:00487323300.014
positive regulation of nucleotide metabolic processGO:00459811140.014
positive regulation of cell cycle processGO:0090068610.014
peptidyl threonine phosphorylationGO:0018107310.014
protein targetingGO:00066051430.014
wnt signaling pathwayGO:00160551880.014
leukocyte apoptotic processGO:0071887710.014
positive regulation of nervous system developmentGO:00519622210.014
regulation of nucleocytoplasmic transportGO:0046822730.014
regulation of purine nucleotide metabolic processGO:19005421690.014
response to ionizing radiationGO:0010212420.014
response to metal ionGO:0010038470.014
regulation of secretionGO:00510462740.014
regulation of protein kinase activityGO:00458592320.014
nuclear importGO:0051170950.014
chromatin assembly or disassemblyGO:0006333160.014
axonogenesisGO:00074092740.014
negative regulation of phosphorus metabolic processGO:00105631840.014
carbohydrate derivative biosynthetic processGO:19011371830.014
negative regulation of dna dependent dna replicationGO:200010410.014
protein localization to nucleusGO:00345041210.014
regulation of secretion by cellGO:19035302490.013
homeostasis of number of cellsGO:00488722100.013
spindle assembly involved in female meiosisGO:000705630.013
protein import into nucleusGO:0006606950.013
guanosine containing compound metabolic processGO:19010681440.013
negative regulation of phosphorylationGO:00423261660.013
positive regulation of apoptotic processGO:00430652170.013
regulation of cell projection organizationGO:00313442060.013
regulation of proteasomal protein catabolic processGO:0061136460.013
regulation of lymphocyte proliferationGO:00506701170.013
leukocyte proliferationGO:00706611720.013
neural tube developmentGO:00219151600.013
regulation of purine nucleotide catabolic processGO:00331211220.013
positive regulation of nucleoside metabolic processGO:0045979910.012
regulation of cellular component biogenesisGO:00440871810.012
heterochromatin organizationGO:007082840.012
lymphocyte proliferationGO:00466511640.012
chromatin remodelingGO:0006338320.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
regulation of cell activationGO:00508652890.012
sister chromatid segregationGO:0000819200.012
mitotic spindle organizationGO:0007052100.012
positive regulation of cell activationGO:00508671580.012
spindle midzone assemblyGO:005125510.012
positive regulation of nucleotide catabolic processGO:0030813880.012
myosin filament assemblyGO:003103420.012
regulation of intracellular protein transportGO:0033157820.012
mitotic g2 dna damage checkpointGO:000709580.012
neural tube formationGO:00018411080.012
regulation of inflammatory responseGO:00507271470.012
cellular chemical homeostasisGO:00550822150.012
regulation of lipid metabolic processGO:00192161180.012
positive regulation of cell divisionGO:0051781310.012
cellular response to growth factor stimulusGO:00713631970.012
tube formationGO:00351481400.012
cellular response to hormone stimulusGO:00328701500.012
neural precursor cell proliferationGO:00613511210.012
guanosine containing compound catabolic processGO:19010691440.012
blastocyst developmentGO:0001824800.012
positive regulation of intracellular transportGO:0032388700.012
regulation of mapk cascadeGO:00434082480.012
regulation of apoptotic signaling pathwayGO:20012331970.012
regulation of leukocyte apoptotic processGO:2000106560.012
regulation of nucleotide catabolic processGO:00308111220.012
cleavage furrow formationGO:003608920.012
negative regulation of intracellular signal transductionGO:19025321670.012
rho protein signal transductionGO:0007266320.012
cellular response to biotic stimulusGO:0071216920.011
dna damage checkpointGO:0000077260.011
lymphocyte differentiationGO:00300982420.011
b cell activationGO:00421131610.011
multicellular organism growthGO:00352641610.011
cytoplasmic transportGO:00164822340.011
response to radiationGO:00093141650.011
peptidyl threonine modificationGO:0018210310.011
protein oligomerizationGO:0051259670.011
regulation of meiosis iGO:006063170.011
regulation of bindingGO:00510981110.011
regulation of nucleotide metabolic processGO:00061401690.011
anion transportGO:00068201770.011
regulation of spindle organizationGO:009022420.011
sensory perceptionGO:00076002450.011
positive regulation of cellular component biogenesisGO:0044089940.011
response to hypoxiaGO:0001666580.011
mitotic recombinationGO:000631230.011
response to oxygen levelsGO:0070482620.011
cellular response to inorganic substanceGO:0071241370.011
camera type eye developmentGO:00430102660.011
myeloid cell differentiationGO:00300992330.011
positive regulation of cell developmentGO:00107202370.011
positive regulation of gtp catabolic processGO:0033126850.011
positive regulation of gtpase activityGO:0043547850.011
regulation of neuron projection developmentGO:00109751690.011
embryonic epithelial tube formationGO:00018381300.011
forebrain developmentGO:00309003020.011
digestive system developmentGO:00551232000.011
regulation of wnt signaling pathwayGO:00301111230.010
negative regulation of cellular protein metabolic processGO:00322692470.010
anatomical structure homeostasisGO:00602491450.010
multi multicellular organism processGO:00447061090.010
lipid biosynthetic processGO:00086101790.010
cell activation involved in immune responseGO:00022631260.010
response to acid chemicalGO:00011011110.010
negative regulation of molecular functionGO:00440922580.010
establishment of protein localization to organelleGO:00725941180.010
muscle cell developmentGO:00550011330.010
regulation of transcription by chromatin organizationGO:003440100.010
stem cell differentiationGO:00488632680.010
positive regulation of protein transportGO:0051222930.010
protein maturationGO:00516041760.010
gtp metabolic processGO:00460391440.010
alpha beta t cell activationGO:0046631910.010
centrosome duplicationGO:0051298160.010

Pole2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.037
cancerDOID:16200.028
organ system cancerDOID:005068600.023