Mus musculus

27 known processes

Mcm6

minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)

(Aliases: Mcmd6,D1Wsu22e,ASP-l1)

Mcm6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein dna complex subunit organizationGO:0071824280.560
Yeast
cellular response to dna damage stimulusGO:00069742070.422
Yeast
dna metabolic processGO:00062593030.363
nucleoside monophosphate metabolic processGO:0009123850.344
Human Yeast
organelle fissionGO:00482851700.317
microtubule cytoskeleton organizationGO:00002261570.284
chromosome separationGO:0051304140.274
dna repairGO:00062811070.249
Yeast
double strand break repairGO:0006302480.225
Yeast
nuclear divisionGO:00002801580.196
dna endoreduplicationGO:004202340.195
nuclear dna replicationGO:003326030.190
Yeast
nucleoside triphosphate metabolic processGO:00091412300.179
Human Yeast
chromatin organizationGO:00063252060.157
nucleobase containing small molecule metabolic processGO:00550863520.156
Human Yeast
negative regulation of chromatin silencingGO:003193610.155
mitotic cell cycleGO:00002781950.155
regulation of transcription by chromatin organizationGO:003440100.150
purine ribonucleotide metabolic processGO:00091502900.143
Human Yeast
purine nucleoside triphosphate metabolic processGO:00091442260.141
Human Yeast
nucleotide metabolic processGO:00091173320.139
Human Yeast
chromosome segregationGO:0007059480.134
chromatin silencingGO:0006342150.127
meiotic nuclear divisionGO:00071261150.124
purine ribonucleoside metabolic processGO:00461282410.121
Human Yeast
purine nucleoside monophosphate catabolic processGO:0009128580.119
Human Yeast
regulation of cell cycleGO:00517262810.116
deoxyribonucleotide biosynthetic processGO:000926360.114
mitotic cell cycle processGO:19030471590.100
regulation of dna dependent dna replication initiationGO:003017430.098
cellular amino acid metabolic processGO:00065201030.094
ribonucleoside triphosphate catabolic processGO:00092031990.091
Human Yeast
organic cyclic compound catabolic processGO:19013612950.090
Human Yeast
aromatic compound catabolic processGO:00194392860.089
Human Yeast
purine containing compound metabolic processGO:00725213110.088
Human Yeast
protein heterotetramerizationGO:005129040.087
nucleotide catabolic processGO:00091662170.086
Human Yeast
meiotic cell cycleGO:00513211220.084
purine nucleoside metabolic processGO:00422782410.081
Human Yeast
nucleoside phosphate catabolic processGO:19012922220.080
Human Yeast
regulation of cell cycle processGO:00105641600.080
ribonucleoside catabolic processGO:00424542060.079
Human Yeast
purine ribonucleoside monophosphate catabolic processGO:0009169570.078
Human Yeast
response to ionizing radiationGO:0010212420.077
dna geometric changeGO:003239270.076
cellular macromolecule catabolic processGO:00442652060.075
nucleoside catabolic processGO:00091642060.073
Human Yeast
microtubule based processGO:00070172360.071
dna recombinationGO:0006310920.070
Yeast
regulation of hydrolase activityGO:00513362460.069
glycosyl compound catabolic processGO:19016582060.066
Human Yeast
glycosyl compound metabolic processGO:19016572460.065
Human Yeast
deoxyribonucleotide metabolic processGO:0009262140.065
glial cell differentiationGO:00100011310.065
nucleoside phosphate biosynthetic processGO:1901293790.065
purine nucleoside monophosphate metabolic processGO:0009126810.063
Human Yeast
humoral immune responseGO:0006959570.062
purine nucleotide metabolic processGO:00061633020.062
Human Yeast
cellular protein catabolic processGO:00442571550.062
mitotic sister chromatid separationGO:005130690.061
sister chromatid segregationGO:0000819200.060
apoptotic signaling pathwayGO:00971903060.060
ribonucleoside monophosphate metabolic processGO:0009161800.058
Human Yeast
organophosphate biosynthetic processGO:00904071220.057
nucleoside metabolic processGO:00091162460.057
Human Yeast
purine ribonucleoside triphosphate catabolic processGO:00092071990.057
Human Yeast
nucleotide biosynthetic processGO:0009165780.057
purine ribonucleoside monophosphate metabolic processGO:0009167800.056
Human Yeast
ribonucleotide metabolic processGO:00092592910.056
Human Yeast
intrinsic apoptotic signaling pathwayGO:00971931320.056
purine containing compound catabolic processGO:00725232130.056
Human Yeast
glial cell developmentGO:0021782540.056
purine nucleoside triphosphate catabolic processGO:00091462030.055
Human Yeast
response to inorganic substanceGO:0010035960.054
nucleoside phosphate metabolic processGO:00067533380.054
Human Yeast
dna unwinding involved in dna replicationGO:000626850.053
purine nucleotide catabolic processGO:00061952110.053
Human Yeast
purine ribonucleotide catabolic processGO:00091542080.051
Human Yeast
nucleoside triphosphate catabolic processGO:00091432050.050
Human Yeast
carbohydrate derivative catabolic processGO:19011362310.049
Human Yeast
ribonucleotide catabolic processGO:00092612080.049
Human Yeast
purine ribonucleoside triphosphate metabolic processGO:00092052200.048
Human Yeast
gene silencingGO:0016458380.048
oxidation reduction processGO:00551143420.047
ribonucleoside metabolic processGO:00091192450.046
Human Yeast
regulation of mitotic cell cycle phase transitionGO:1901990730.046
engulfment of apoptotic cellGO:004365230.046
double strand break repair via homologous recombinationGO:0000724210.045
Yeast
developmental cell growthGO:0048588840.044
dna dependent dna replicationGO:0006261240.044
negative regulation of mitotic cell cycle phase transitionGO:1901991450.044
intracellular mrna localizationGO:000829840.044
cellular response to growth factor stimulusGO:00713631970.043
negative regulation of nucleoside metabolic processGO:0045978110.043
regulation of cellular catabolic processGO:00313292420.043
negative regulation of gene silencingGO:006096920.042
ribose phosphate metabolic processGO:00196932910.041
Human Yeast
heterocycle catabolic processGO:00467002800.039
Human Yeast
histone lysine methylationGO:0034968500.039
methylationGO:00322591340.039
carbohydrate derivative biosynthetic processGO:19011371830.038
protein maturationGO:00516041760.037
endocytosisGO:00068971680.037
response to testosteroneGO:003357430.037
histone methylationGO:0016571710.036
blood circulationGO:00080151950.036
cellular ketone metabolic processGO:0042180840.036
mitotic sister chromatid segregationGO:0000070140.036
organophosphate catabolic processGO:00464342320.036
Human Yeast
dna replicationGO:0006260520.035
organonitrogen compound biosynthetic processGO:19015661920.035
atp catabolic processGO:0006200550.035
Human Yeast
heterochromatin organizationGO:007082840.035
atp metabolic processGO:0046034750.034
Human Yeast
ras protein signal transductionGO:0007265770.034
purine nucleoside catabolic processGO:00061522050.034
Human Yeast
membrane organizationGO:00610242450.034
purine ribonucleoside catabolic processGO:00461302050.034
Human Yeast
chromatin modificationGO:00165681870.033
male gamete generationGO:00482322850.033
camera type eye developmentGO:00430102660.033
chromatin assemblyGO:0031497130.032
alpha amino acid metabolic processGO:1901605590.032
gliogenesisGO:00420631410.032
g1 s transition of mitotic cell cycleGO:0000082570.032
response to organic cyclic compoundGO:00140701980.032
protein processingGO:00164851630.030
response to organonitrogen compoundGO:00102432460.029
cell growthGO:00160491300.028
dna replication initiationGO:000627050.028
Yeast
cell cycle checkpointGO:0000075470.028
inner cell mass cell proliferationGO:0001833150.028
response to metal ionGO:0010038470.028
monocarboxylic acid metabolic processGO:00327871910.028
multicellular organismal agingGO:0010259240.027
regulation of response to woundingGO:19030341890.027
regulation of cellular amino acid metabolic processGO:000652150.027
mrna splicing via spliceosomeGO:0000398430.027
positive regulation of apoptotic processGO:00430652170.027
cell cycle g1 s phase transitionGO:0044843570.027
negative regulation of atpase activityGO:003278020.027
regulation of purine nucleotide metabolic processGO:19005421690.027
cofactor metabolic processGO:0051186800.026
purine nucleobase biosynthetic processGO:000911330.025
nucleoside monophosphate catabolic processGO:0009125590.025
Human Yeast
response to growth factorGO:00708481980.025
mitotic nuclear divisionGO:0007067480.024
response to light stimulusGO:00094161350.024
ubiquitin dependent protein catabolic processGO:00065111290.024
rhythmic processGO:00485111740.024
leukocyte activation involved in immune responseGO:00023661260.024
protein methylationGO:0006479810.023
cellular response to abiotic stimulusGO:0071214560.023
spermatogenesisGO:00072832840.023
neural precursor cell proliferationGO:00613511210.023
regulation of defense responseGO:00313472330.023
cell adhesionGO:00071553290.023
regulation of neuron projection developmentGO:00109751690.022
positive regulation of programmed cell deathGO:00430682180.022
response to radiationGO:00093141650.022
dna dependent dna replication maintenance of fidelityGO:004500530.022
germ cell developmentGO:00072811850.021
Worm Fly
response to oxidative stressGO:00069791230.021
circulatory system processGO:00030131970.021
regulation of protein catabolic processGO:00421761080.020
intrahepatic bile duct developmentGO:003562220.020
amine metabolic processGO:0009308450.020
histone modificationGO:00165701590.020
gonad developmentGO:00084061410.020
Worm
positive regulation of protein phosphorylationGO:00019342420.020
translesion synthesisGO:001998510.019
sulfur compound metabolic processGO:00067901000.019
double strand break repair via nonhomologous end joiningGO:0006303100.019
production of molecular mediator of immune responseGO:00024401030.019
regulation of cell cycle phase transitionGO:1901987770.019
recombinational repairGO:0000725210.018
Yeast
regulation of atp metabolic processGO:1903578170.018
sensory organ morphogenesisGO:00905962420.018
leukocyte migrationGO:00509001240.017
negative regulation of molecular functionGO:00440922580.017
myeloid cell differentiationGO:00300992330.017
positive regulation of cellular amine metabolic processGO:003324050.017
ribonucleoside triphosphate metabolic processGO:00091992200.016
Human Yeast
inflammatory responseGO:00069542440.016
heart contractionGO:0060047930.016
coenzyme metabolic processGO:0006732520.016
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.016
nitrogen compound transportGO:00717052710.016
gland developmentGO:00487323300.016
regulation of cellular ketone metabolic processGO:0010565660.016
cell type specific apoptotic processGO:00972852680.016
uronic acid metabolic processGO:000606320.016
positive regulation of intracellular transportGO:0032388700.016
neuron deathGO:00709971540.016
regulation of mitotic cell cycleGO:00073461260.015
rna splicingGO:0008380540.015
development of primary sexual characteristicsGO:00451371430.015
Worm
organonitrogen compound catabolic processGO:19015652640.015
Human Yeast
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
meiotic cell cycle processGO:1903046770.015
cellular homeostasisGO:00197252400.015
regulation of nucleotide metabolic processGO:00061401690.015
regulation of heart contractionGO:0008016770.015
macromolecule methylationGO:00434141200.015
positive regulation of protein modification processGO:00314012990.015
positive regulation of cellular catabolic processGO:00313311480.015
blastocyst developmentGO:0001824800.014
lymphocyte mediated immunityGO:00024491390.014
female gamete generationGO:0007292740.014
Worm Fly
positive regulation of cellular amino acid metabolic processGO:004576430.014
organism emergence from protective structureGO:007168440.014
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.014
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.014
protein localization to organelleGO:00333651850.014
cellular amine metabolic processGO:0044106440.014
regulation of neuron apoptotic processGO:00435231220.014
cellular response to cytokine stimulusGO:00713451890.014
maintenance of locationGO:0051235890.014
oocyte anterior posterior axis specificationGO:000731420.014
ribonucleoside monophosphate catabolic processGO:0009158570.013
Human Yeast
folic acid containing compound metabolic processGO:000676030.013
maternal process involved in female pregnancyGO:0060135320.013
cell divisionGO:00513011200.013
regulation of organelle organizationGO:00330432890.013
cell maturationGO:00484691270.013
genitalia developmentGO:0048806370.013
Worm
positive regulation of cell deathGO:00109422240.013
blastocyst growthGO:0001832230.013
negative regulation of cellular protein metabolic processGO:00322692470.013
sister chromatid cohesionGO:0007062120.013
regulation of cellular amine metabolic processGO:0033238200.013
response to uvGO:0009411440.013
negative regulation of gene expression epigeneticGO:0045814150.013
regulation of inflammatory responseGO:00507271470.013
hatchingGO:003518840.013
positive regulation of chromosome organizationGO:2001252330.013
liver developmentGO:0001889660.013
hepaticobiliary system developmentGO:0061008670.013
somatic recombination of immunoglobulin gene segmentsGO:0016447420.012
cellular protein complex assemblyGO:00436231160.012
regulation of cell sizeGO:0008361720.012
regulation of proteolysisGO:00301621640.012
positive regulation of neuron differentiationGO:00456661410.012
regulation of embryonic developmentGO:0045995710.012
placenta developmentGO:00018901400.012
rna processingGO:00063961050.012
cell fate commitmentGO:00451652100.012
Fly
translationGO:0006412930.012
immunoglobulin productionGO:0002377730.012
asymmetric stem cell divisionGO:009872230.012
ossificationGO:00015032160.012
regulation of intracellular transportGO:00323861590.012
regulation of cysteine type endopeptidase activityGO:2000116650.012
protein oligomerizationGO:0051259670.012
cellular lipid metabolic processGO:00442553230.011
pancreas developmentGO:0031016570.011
reciprocal dna recombinationGO:0035825160.011
regulation of membrane potentialGO:00423911920.011
protein alkylationGO:0008213810.011
covalent chromatin modificationGO:00165691630.011
single organism cell adhesionGO:00986021560.011
regulation of cytoplasmic transportGO:19036491120.011
antimicrobial peptide biosynthetic processGO:000277720.011
response to alcoholGO:0097305480.011
regulation of lymphocyte activationGO:00512492400.011
ion transmembrane transportGO:00342203610.011
response to acid chemicalGO:00011011110.011
receptor mediated endocytosisGO:0006898510.011
multi multicellular organism processGO:00447061090.011
proteasomal protein catabolic processGO:0010498980.011
microtubule organizing center organizationGO:0031023280.011
neuron apoptotic processGO:00514021420.011
transmembrane transportGO:00550854120.011
regulation of blood circulationGO:1903522930.011
organic anion transportGO:00157111370.011
maternal placenta developmentGO:0001893200.011
ovulationGO:0030728150.011
carbohydrate homeostasisGO:00335001280.011
positive regulation of cell cycle phase transitionGO:1901989170.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.011
cell activation involved in immune responseGO:00022631260.011
response to temperature stimulusGO:0009266550.011
b cell activation involved in immune responseGO:0002312500.011
negative regulation of cell cycleGO:00457861230.011
regulation of cell projection organizationGO:00313442060.011
rna catabolic processGO:0006401290.011
positive regulation of histone modificationGO:0031058280.010
heart morphogenesisGO:00030071780.010
connective tissue developmentGO:00614481790.010
regulation of rna splicingGO:0043484370.010
negative regulation of intracellular signal transductionGO:19025321670.010
regulation of protein transportGO:00512231630.010
regulation of cell morphogenesis involved in differentiationGO:00107691510.010
positive regulation of organelle organizationGO:00106381280.010
regulation of cell migrationGO:00303342190.010

Mcm6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.223
cancerDOID:16200.097
organ system cancerDOID:005068600.056
gastrointestinal system cancerDOID:311900.043
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
intestinal cancerDOID:1015500.020
large intestine cancerDOID:567200.020
breast cancerDOID:161200.013
thoracic cancerDOID:509300.013