Mus musculus

57 known processes

Mcm2

minichromosome maintenance deficient 2 mitotin (S. cerevisiae)

(Aliases: Mcmd2,BM28,AW476101,AA959861,mKIAA0030,CDCL1)

Mcm2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna endoreduplicationGO:004202341.000
dna dependent dna replicationGO:0006261240.999
dna metabolic processGO:00062593030.999
nuclear dna replicationGO:003326030.998
Yeast
recombinational repairGO:0000725210.998
Yeast
double strand break repair via homologous recombinationGO:0000724210.995
Yeast
cellular response to dna damage stimulusGO:00069742070.985
Yeast
dna replication initiationGO:000627050.978
Human
dna unwinding involved in dna replicationGO:000626850.975
dna repairGO:00062811070.973
Yeast
dna replicationGO:0006260520.934
dna geometric changeGO:003239270.932
dna duplex unwindingGO:003250870.930
double strand break repairGO:0006302480.916
Yeast
meiotic cell cycle processGO:1903046770.915
dna recombinationGO:0006310920.906
Yeast
negative regulation of gene expression epigeneticGO:0045814150.813
regulation of cell cycleGO:00517262810.799
meiosis iGO:0007127600.784
regulation of transcription by chromatin organizationGO:003440100.754
mitotic cell cycleGO:00002781950.740
dna conformation changeGO:0071103370.734
purine nucleoside catabolic processGO:00061522050.674
Yeast
cell cycle checkpointGO:0000075470.664
meiotic cell cycleGO:00513211220.655
regulation of dna dependent dna replication initiationGO:003017430.646
dna integrity checkpointGO:0031570280.643
meiotic nuclear divisionGO:00071261150.640
chromatin organizationGO:00063252060.627
mitotic cell cycle processGO:19030471590.617
base excision repairGO:000628490.611
microtubule cytoskeleton organizationGO:00002261570.610
gene silencingGO:0016458380.563
sister chromatid cohesionGO:0007062120.563
regulation of nuclear cell cycle dna replicationGO:003326220.552
chromatin silencingGO:0006342150.547
regulation of dna dependent dna replicationGO:009032980.528
microtubule based processGO:00070172360.517
negative regulation of chromatin silencingGO:003193610.509
protein dna complex subunit organizationGO:0071824280.486
reciprocal dna recombinationGO:0035825160.423
purine ribonucleotide metabolic processGO:00091502900.419
Yeast
regulation of cell cycle processGO:00105641600.380
negative regulation of cell cycleGO:00457861230.370
chromosome segregationGO:0007059480.370
regulation of mitotic cell cycle phase transitionGO:1901990730.344
dna dependent dna replication maintenance of fidelityGO:004500530.341
genitalia developmentGO:0048806370.337
Worm
gonad developmentGO:00084061410.332
Worm
purine ribonucleoside metabolic processGO:00461282410.331
Yeast
chromosome organization involved in meiosisGO:0070192390.324
nucleoside triphosphate metabolic processGO:00091412300.301
Yeast
purine containing compound metabolic processGO:00725213110.301
Yeast
heterocycle catabolic processGO:00467002800.288
Yeast
development of primary sexual characteristicsGO:00451371430.267
Worm
translesion synthesisGO:001998510.265
circadian temperature homeostasisGO:006008620.263
mitotic sister chromatid segregationGO:0000070140.259
intra s dna damage checkpointGO:003157340.256
maintenance of dna methylationGO:001021640.251
rna dependent dna replicationGO:000627830.247
endocytosisGO:00068971680.235
organelle fissionGO:00482851700.222
nucleobase containing small molecule metabolic processGO:00550863520.213
Yeast
ribonucleotide catabolic processGO:00092612080.210
Yeast
dna damage checkpointGO:0000077260.206
deoxyribonucleotide biosynthetic processGO:000926360.205
establishment of organelle localizationGO:00516561220.202
mitotic cell cycle checkpointGO:0007093310.187
engulfment of apoptotic cellGO:004365230.187
cell cycle g1 s phase transitionGO:0044843570.181
nuclear divisionGO:00002801580.169
protein localization to organelleGO:00333651850.165
nucleoside metabolic processGO:00091162460.164
Yeast
regulation of dna replicationGO:0006275170.151
intrinsic apoptotic signaling pathwayGO:00971931320.141
negative regulation of mitotic cell cycleGO:0045930580.140
purine nucleoside triphosphate metabolic processGO:00091442260.131
Yeast
regulation of cellular amino acid metabolic processGO:000652150.123
camera type eye developmentGO:00430102660.121
double strand break repair via nonhomologous end joiningGO:0006303100.121
cellular response to radiationGO:0071478280.120
cellular amino acid metabolic processGO:00065201030.120
negative regulation of mitotic cell cycle phase transitionGO:1901991450.117
meiotic chromosome segregationGO:0045132190.115
ribonucleoside triphosphate catabolic processGO:00092031990.115
Yeast
receptor mediated endocytosisGO:0006898510.115
regulation of circadian sleep wake cycleGO:004274930.112
mitotic g2 dna damage checkpointGO:000709580.109
regulation of organelle organizationGO:00330432890.106
circadian sleep wake cycleGO:004274550.106
response to radiationGO:00093141650.103
regulation of mitotic cell cycleGO:00073461260.099
nucleotide excision repairGO:0006289130.096
purine ribonucleoside triphosphate catabolic processGO:00092071990.091
Yeast
reciprocal meiotic recombinationGO:0007131160.087
deoxyribonucleotide metabolic processGO:0009262140.085
negative regulation of gene silencingGO:006096920.085
cellular nitrogen compound catabolic processGO:00442702800.082
Yeast
sister chromatid segregationGO:0000819200.081
negative regulation of cell cycle phase transitionGO:1901988480.079
gtp metabolic processGO:00460391440.079
nucleoside phosphate catabolic processGO:19012922220.078
Yeast
hatchingGO:003518840.077
cellular amine metabolic processGO:0044106440.076
response to light stimulusGO:00094161350.075
regulation of cell cycle phase transitionGO:1901987770.074
epithelial tube morphogenesisGO:00605623030.072
positive regulation of intracellular transportGO:0032388700.070
mitotic sister chromatid cohesionGO:000706410.070
regulation of cytoplasmic transportGO:19036491120.070
coenzyme metabolic processGO:0006732520.066
response to metal ionGO:0010038470.063
regulation of hydrolase activityGO:00513362460.063
Yeast
nucleotide metabolic processGO:00091173320.063
Yeast
ribose phosphate metabolic processGO:00196932910.062
Yeast
mitotic centrosome separationGO:000710040.062
nucleocytoplasmic transportGO:00069131390.062
nucleosome disassemblyGO:000633710.060
aromatic compound catabolic processGO:00194392860.059
Yeast
protein ubiquitinationGO:00165671710.058
purine nucleoside metabolic processGO:00422782410.058
Yeast
apoptotic signaling pathwayGO:00971903060.058
ribonucleotide metabolic processGO:00092592910.058
Yeast
glycosyl compound catabolic processGO:19016582060.057
Yeast
regulation of nucleotide catabolic processGO:00308111220.057
Yeast
organic cyclic compound catabolic processGO:19013612950.057
Yeast
purine ribonucleotide catabolic processGO:00091542080.057
Yeast
purine ribonucleoside catabolic processGO:00461302050.055
Yeast
organonitrogen compound catabolic processGO:19015652640.055
Yeast
cellular ketone metabolic processGO:0042180840.055
amine metabolic processGO:0009308450.055
intracellular protein transportGO:00068862040.054
dna biosynthetic processGO:0071897220.054
purine containing compound catabolic processGO:00725232130.054
Yeast
nucleoside triphosphate catabolic processGO:00091432050.054
Yeast
heterochromatin organizationGO:007082840.052
spindle assembly involved in female meiosisGO:000705630.050
purine nucleoside monophosphate catabolic processGO:0009128580.050
Yeast
positive regulation of gtpase activityGO:0043547850.048
dna replication checkpointGO:000007620.047
rna catabolic processGO:0006401290.046
regulation of chromosome organizationGO:0033044830.046
cellular response to abiotic stimulusGO:0071214560.045
cell divisionGO:00513011200.045
response to organic cyclic compoundGO:00140701980.045
ribonucleoside metabolic processGO:00091192450.045
Yeast
negative regulation of cell cycle processGO:0010948690.045
regulation of cytoskeleton organizationGO:00514931220.044
positive regulation of cell cycle phase transitionGO:1901989170.044
response to testosteroneGO:003357430.044
regulation of cell cycle g2 m phase transitionGO:1902749100.044
purine nucleotide metabolic processGO:00061633020.044
Yeast
membrane organizationGO:00610242450.043
regulation of intracellular protein transportGO:0033157820.042
purine ribonucleoside triphosphate metabolic processGO:00092052200.042
Yeast
mitotic recombinationGO:000631230.042
spindle midzone assemblyGO:005125510.042
response to purine containing compoundGO:0014074280.041
regulation of chromatin silencingGO:003193520.041
mitotic nuclear divisionGO:0007067480.040
purine nucleoside triphosphate catabolic processGO:00091462030.040
Yeast
regulation of intracellular transportGO:00323861590.040
regulation of protein localizationGO:00328802310.040
synapsisGO:0007129340.040
purine ribonucleoside monophosphate catabolic processGO:0009169570.039
Yeast
glycosyl compound metabolic processGO:19016572460.039
Yeast
regulation of gtp catabolic processGO:00331241130.039
response to inorganic substanceGO:0010035960.039
cytoplasmic transportGO:00164822340.039
positive regulation of cellular amine metabolic processGO:003324050.038
telomere maintenance via telomeraseGO:000700410.037
organophosphate catabolic processGO:00464342320.037
Yeast
protein importGO:00170381010.037
regulation of cell divisionGO:0051302760.037
nucleotide catabolic processGO:00091662170.036
Yeast
regulation of purine nucleotide catabolic processGO:00331211220.036
Yeast
dna modificationGO:0006304500.036
sensory organ morphogenesisGO:00905962420.036
regulation of nucleoside metabolic processGO:00091181300.035
Yeast
locomotory behaviorGO:00076261950.035
regulation of cell motilityGO:20001452360.034
ribonucleoside catabolic processGO:00424542060.034
Yeast
regulation of purine nucleotide metabolic processGO:19005421690.034
Yeast
g2 m transition of mitotic cell cycleGO:0000086200.034
macromolecule catabolic processGO:00090572810.033
gtp catabolic processGO:00061841430.033
cellular protein catabolic processGO:00442571550.033
regulation of cellular amine metabolic processGO:0033238200.033
cation transportGO:00068123990.033
chromatin modificationGO:00165681870.031
regulation of cellular ketone metabolic processGO:0010565660.031
negative regulation of molecular functionGO:00440922580.031
Yeast
positive regulation of nucleotide catabolic processGO:0030813880.030
cellular response to light stimulusGO:0071482190.030
s adenosylhomocysteine metabolic processGO:004649810.030
release of cytochrome c from mitochondriaGO:0001836230.030
ribonucleoside triphosphate metabolic processGO:00091992200.030
Yeast
positive regulation of gtp catabolic processGO:0033126850.030
cellular homeostasisGO:00197252400.030
nitrogen compound transportGO:00717052710.030
single organism nuclear importGO:1902593950.030
inner cell mass cell proliferationGO:0001833150.029
nuclear transportGO:00511691390.029
cell cell signaling involved in cell fate commitmentGO:0045168350.029
nucleoside catabolic processGO:00091642060.029
Yeast
lymphocyte proliferationGO:00466511640.029
lateral inhibitionGO:004633110.028
regulation of histone modificationGO:0031056560.028
positive regulation of purine nucleotide metabolic processGO:19005441140.027
dna methylationGO:0006306430.027
humoral immune responseGO:0006959570.027
positive regulation of cellular catabolic processGO:00313311480.027
s adenosylmethionine metabolic processGO:004650020.027
regulation of circadian rhythmGO:0042752580.027
regulation of ran gtpase activityGO:003231630.027
nucleoside monophosphate metabolic processGO:0009123850.027
Yeast
regulation of chromatin modificationGO:1903308570.027
cell growthGO:00160491300.026
body morphogenesisGO:0010171450.026
protein import into nucleusGO:0006606950.026
protein targetingGO:00066051430.026
regulation of cellular response to stressGO:00801351590.025
purine nucleotide catabolic processGO:00061952110.025
Yeast
response to xenobiotic stimulusGO:0009410130.025
positive regulation of hydrolase activityGO:00513451480.025
metaphase plate congressionGO:005131020.025
multicellular organismal homeostasisGO:00488711640.025
striated muscle myosin thick filament assemblyGO:007168810.025
positive regulation of nucleotide metabolic processGO:00459811140.025
carbohydrate derivative catabolic processGO:19011362310.024
Yeast
nucleobase biosynthetic processGO:004611230.024
histone phosphorylationGO:001657290.024
regulation of cell migrationGO:00303342190.024
mitotic cytokinesisGO:000028140.023
organophosphate biosynthetic processGO:00904071220.023
nucleoside phosphate metabolic processGO:00067533380.023
Yeast
protein modification by small protein conjugation or removalGO:00706472070.023
protein heterotetramerizationGO:005129040.022
blood circulationGO:00080151950.022
regulation of double strand break repair via homologous recombinationGO:001056920.022
organonitrogen compound biosynthetic processGO:19015661920.022
chromatin assembly or disassemblyGO:0006333160.022
response to cadmium ionGO:004668680.022
positive regulation of cellular amino acid metabolic processGO:004576430.021
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.021
methylationGO:00322591340.021
negative regulation of protein modification processGO:00314001630.021
regulation of bindingGO:00510981110.021
cellular response to organonitrogen compoundGO:00714171450.021
negative regulation of histone h3 k9 methylationGO:005157340.021
spindle organizationGO:0007051280.020
peptidyl amino acid modificationGO:00181933360.020
dna hypermethylationGO:004402630.020
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.020
branching morphogenesis of an epithelial tubeGO:00487541590.020
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.020
developmental cell growthGO:0048588840.020
protein autoprocessingGO:001654020.020
ion transmembrane transportGO:00342203610.020
establishment of protein localization to organelleGO:00725941180.020
peptidyl threonine phosphorylationGO:0018107310.020
metal ion homeostasisGO:00550651890.019
cellular protein complex assemblyGO:00436231160.019
negative regulation of cell proliferationGO:00082852960.019
circulatory system processGO:00030131970.019
carbohydrate derivative biosynthetic processGO:19011371830.019
mitotic sister chromatid separationGO:005130690.019
glial cell differentiationGO:00100011310.019
response to temperature stimulusGO:0009266550.019
cellular macromolecule catabolic processGO:00442652060.019
positive regulation of nucleoside metabolic processGO:0045979910.018
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.018
female gamete generationGO:0007292740.018
organism emergence from protective structureGO:007168440.018
cytokinesisGO:0000910170.018
cofactor metabolic processGO:0051186800.018
cell fate commitmentGO:00451652100.018
negative regulation of cell developmentGO:00107211690.018
positive regulation of protein modification processGO:00314012990.018
positive regulation of histone modificationGO:0031058280.017
positive regulation of cytoplasmic transportGO:1903651400.017
negative regulation of phosphorylationGO:00423261660.017
positive regulation of organelle organizationGO:00106381280.017
homeostasis of number of cellsGO:00488722100.017
atp catabolic processGO:0006200550.017
Yeast
cellular response to acid chemicalGO:0071229680.017
guanosine containing compound metabolic processGO:19010681440.017
positive regulation of dna templated transcription elongationGO:003278620.017
regulation of secretionGO:00510462740.017
multicellular organismal agingGO:0010259240.017
Worm
intracellular mrna localizationGO:000829840.016
mitotic chromosome condensationGO:000707610.016
positive regulation of cell cycleGO:0045787920.016
regulation of protein transportGO:00512231630.016
protein processingGO:00164851630.016
protein catabolic processGO:00301632210.016
regulation of g2 m transition of mitotic cell cycleGO:0010389100.016
rhythmic processGO:00485111740.016
regulation of apoptotic signaling pathwayGO:20012331970.016
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
Yeast
centrosome organizationGO:0051297260.016
g2 dna damage checkpointGO:003157280.016
regulation of kinase activityGO:00435492490.015
neural tube developmentGO:00219151600.015
viral release from host cellGO:001907660.015
negative regulation of cellular component organizationGO:00511291940.015
mrna transportGO:0051028130.015
nucleic acid phosphodiester bond hydrolysisGO:0090305490.015
nuclear exportGO:0051168340.015
dendrite developmentGO:00163581150.015
regulation of ras gtpase activityGO:0032318880.015
meiotic chromosome separationGO:005130750.015
negative regulation of phosphate metabolic processGO:00459361840.015
Yeast
regulation of chromosome segregationGO:0051983210.015
response to organonitrogen compoundGO:00102432460.015
digestive system developmentGO:00551232000.015
regulation of transferase activityGO:00513382630.015
anatomical structure homeostasisGO:00602491450.014
negative regulation of organelle organizationGO:0010639900.014
regulation of cellular catabolic processGO:00313292420.014
Yeast
rna processingGO:00063961050.014
positive regulation of atpase activityGO:003278130.014
histone modificationGO:00165701590.014
positive regulation of protein phosphorylationGO:00019342420.014
negative regulation of cellular protein metabolic processGO:00322692470.014
regulation of nucleotide metabolic processGO:00061401690.014
Yeast
guanosine containing compound catabolic processGO:19010691440.014
response to oxidative stressGO:00069791230.013
protein localization to chromosomeGO:003450260.013
copulationGO:000762070.013
cell cell junction organizationGO:0045216720.013
regulation of protein localization to nucleusGO:1900180600.013
g1 s transition of mitotic cell cycleGO:0000082570.013
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.013
meiotic sister chromatid segregationGO:004514460.013
regulation of dna bindingGO:0051101390.013
leukocyte proliferationGO:00706611720.013
negative regulation of kinase activityGO:0033673810.013
cell cycle g2 m phase transitionGO:0044839200.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
Yeast
non recombinational repairGO:0000726100.013
spermatogenesisGO:00072832840.013
nucleus organizationGO:0006997450.013
morphogenesis of a branching epitheliumGO:00611381930.013
proteolysis involved in cellular protein catabolic processGO:00516031470.012
covalent chromatin modificationGO:00165691630.012
chromatin disassemblyGO:003149810.012
regulation of meiosis iGO:006063170.012
negative regulation of nucleoside metabolic processGO:0045978110.012
Yeast
regulation of establishment of protein localizationGO:00702011810.012
peptide secretionGO:00027901140.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
negative regulation of intracellular signal transductionGO:19025321670.012
cellular metal ion homeostasisGO:00068751510.012
organelle localizationGO:00516401790.012
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225480.012
ameboidal type cell migrationGO:00016671280.012
small gtpase mediated signal transductionGO:0007264970.011
muscle cell differentiationGO:00426922610.011
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.011
cellularizationGO:000734910.011
nucleobase containing compound transportGO:0015931270.011
cellular response to growth factor stimulusGO:00713631970.011
cellular response to hormone stimulusGO:00328701500.011
apoptotic mitochondrial changesGO:0008637480.011
heart contractionGO:0060047930.011
pharynx developmentGO:006046510.011
resolution of meiotic recombination intermediatesGO:000071240.011
amide transportGO:00428861380.011
learningGO:0007612980.011
response to steroid hormoneGO:0048545560.011
positive regulation of fibroblast proliferationGO:0048146200.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
regulation of response to dna damage stimulusGO:2001020340.011
endomembrane system organizationGO:00102561470.011
negative regulation of protein phosphorylationGO:00019331260.011
chromosome condensationGO:0030261100.011
positive regulation of g2 m transition of mitotic cell cycleGO:001097150.011
mitochondrion organizationGO:00070051340.011
regulation of dna damage checkpointGO:200000130.010
nucleoside monophosphate catabolic processGO:0009125590.010
Yeast
response to alcoholGO:0097305480.010
positive regulation of cell cycle processGO:0090068610.010
negative regulation of cell cycle g1 s phase transitionGO:1902807180.010
regulation of cysteine type endopeptidase activityGO:2000116650.010
cell type specific apoptotic processGO:00972852680.010
cellular chemical homeostasisGO:00550822150.010
regulation of microtubule cytoskeleton organizationGO:0070507370.010
cognitionGO:00508901490.010
gene conversionGO:003582220.010
cellular response to cytokine stimulusGO:00713451890.010
localization within membraneGO:005166840.010
positive regulation of meiotic cell cycleGO:0051446150.010
germ cell developmentGO:00072811850.010

Mcm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.295
cancerDOID:16200.295
gastrointestinal system cancerDOID:311900.295
organ system cancerDOID:005068600.295
intestinal cancerDOID:1015500.117
inherited metabolic disorderDOID:65500.115
disease of metabolismDOID:001466700.115
large intestine cancerDOID:567200.093
nervous system diseaseDOID:86300.034
neuropathyDOID:87000.034
disease of anatomical entityDOID:700.034
peripheral neuropathyDOID:006005300.034
carbohydrate metabolic disorderDOID:297800.019
hereditary sensory neuropathyDOID:005054800.011