Mus musculus

56 known processes

Ext2

exostoses (multiple) 2

(Aliases: AI893565)

Ext2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ras protein signal transductionGO:0007265770.101
cellular amine metabolic processGO:0044106440.070
carbohydrate derivative catabolic processGO:19011362310.061
regulation of cellular amine metabolic processGO:0033238200.059
regulation of cellular amino acid metabolic processGO:000652150.058
axonogenesisGO:00074092740.055
Zebrafish Mouse
negative regulation of protein metabolic processGO:00512482820.054
amine metabolic processGO:0009308450.051
cellular response to growth factor stimulusGO:00713631970.050
Zebrafish
nucleoside phosphate metabolic processGO:00067533380.050
protein modification by small protein conjugation or removalGO:00706472070.048
macromolecule catabolic processGO:00090572810.047
regulation of nucleotide metabolic processGO:00061401690.047
nucleotide metabolic processGO:00091173320.047
response to growth factorGO:00708481980.047
Zebrafish
rho protein signal transductionGO:0007266320.045
cellular amino acid metabolic processGO:00065201030.044
regulation of hydrolase activityGO:00513362460.044
positive regulation of cellular amine metabolic processGO:003324050.043
ribonucleotide metabolic processGO:00092592910.043
chemotaxisGO:00069352470.043
Zebrafish Mouse
negative regulation of cellular protein metabolic processGO:00322692470.042
heterocycle catabolic processGO:00467002800.042
negative regulation of growthGO:0045926990.041
protein maturationGO:00516041760.040
cellular nitrogen compound catabolic processGO:00442702800.039
positive regulation of cellular amino acid metabolic processGO:004576430.038
ribonucleoside catabolic processGO:00424542060.037
cellular ketone metabolic processGO:0042180840.037
purine nucleoside triphosphate metabolic processGO:00091442260.036
nucleoside triphosphate catabolic processGO:00091432050.036
extracellular structure organizationGO:00430621480.036
Zebrafish
negative regulation of molecular functionGO:00440922580.035
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.035
Fly
nucleoside metabolic processGO:00091162460.035
organonitrogen compound catabolic processGO:19015652640.035
purine nucleotide metabolic processGO:00061633020.034
negative regulation of nervous system developmentGO:00519611560.034
regulation of protein kinase activityGO:00458592320.033
muscle cell differentiationGO:00426922610.033
blood vessel morphogenesisGO:00485142850.033
glycosyl compound metabolic processGO:19016572460.033
leukocyte differentiationGO:00025213420.033
skeletal system developmentGO:00015013560.032
Zebrafish Mouse
positive regulation of apoptotic processGO:00430652170.032
regulation of apoptotic signaling pathwayGO:20012331970.032
ribose phosphate metabolic processGO:00196932910.032
forebrain developmentGO:00309003020.032
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858240.032
ribonucleotide catabolic processGO:00092612080.031
purine containing compound metabolic processGO:00725213110.031
regulation of cellular ketone metabolic processGO:0010565660.031
membrane organizationGO:00610242450.031
small gtpase mediated signal transductionGO:0007264970.031
regulation of transferase activityGO:00513382630.031
regulation of cell morphogenesis involved in differentiationGO:00107691510.030
Zebrafish
glycosyl compound catabolic processGO:19016582060.030
ubiquitin dependent protein catabolic processGO:00065111290.030
organic cyclic compound catabolic processGO:19013612950.030
negative regulation of cell developmentGO:00107211690.030
defense response to other organismGO:00985421970.029
organophosphate catabolic processGO:00464342320.029
regulation of purine nucleotide metabolic processGO:19005421690.029
immune effector processGO:00022523210.029
spermatogenesisGO:00072832840.029
purine ribonucleotide metabolic processGO:00091502900.028
nucleoside triphosphate metabolic processGO:00091412300.028
bone developmentGO:00603481200.028
aromatic compound catabolic processGO:00194392860.028
positive regulation of cell deathGO:00109422240.028
regulation of cell activationGO:00508652890.028
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
positive regulation of protein modification processGO:00314012990.028
cellular macromolecule catabolic processGO:00442652060.028
purine nucleoside metabolic processGO:00422782410.028
positive regulation of hydrolase activityGO:00513451480.028
ribonucleoside triphosphate metabolic processGO:00091992200.028
stem cell developmentGO:00488642190.027
blood circulationGO:00080151950.027
cation transportGO:00068123990.027
regulation of cellular catabolic processGO:00313292420.027
protein processingGO:00164851630.027
regulation of organelle organizationGO:00330432890.027
protein palmitoylationGO:0018345140.027
regulation of proteolysisGO:00301621640.026
regulation of protein localizationGO:00328802310.026
nucleoside catabolic processGO:00091642060.026
nucleobase containing small molecule metabolic processGO:00550863520.026
positive regulation of nucleotide metabolic processGO:00459811140.025
transforming growth factor beta receptor signaling pathwayGO:0007179710.025
purine nucleoside triphosphate catabolic processGO:00091462030.025
negative regulation of cellular amine metabolic processGO:003323910.025
cartilage developmentGO:00512161400.025
Zebrafish
regulation of cell motilityGO:20001452360.024
nucleotide catabolic processGO:00091662170.024
positive regulation of cellular catabolic processGO:00313311480.024
transmembrane transportGO:00550854120.024
response to transforming growth factor betaGO:0071559880.024
ameboidal type cell migrationGO:00016671280.024
organonitrogen compound biosynthetic processGO:19015661920.024
Zebrafish Fly
organelle localizationGO:00516401790.024
meiotic cell cycleGO:00513211220.023
negative regulation of phosphate metabolic processGO:00459361840.023
nuclear transportGO:00511691390.023
protein modification by small protein conjugationGO:00324461870.023
cell adhesionGO:00071553290.023
purine ribonucleotide catabolic processGO:00091542080.023
modification dependent protein catabolic processGO:00199411330.023
regulation of lymphocyte activationGO:00512492400.023
ossificationGO:00015032160.023
Zebrafish
cytoplasmic transportGO:00164822340.023
positive regulation of proteolysisGO:0045862850.023
protein catabolic processGO:00301632210.022
purine ribonucleoside metabolic processGO:00461282410.022
purine ribonucleoside catabolic processGO:00461302050.022
carbohydrate metabolic processGO:00059752300.022
Fly
compound eye developmentGO:004874910.022
negative regulation of phosphorus metabolic processGO:00105631840.022
morphogenesis of embryonic epitheliumGO:00163311590.022
purine containing compound catabolic processGO:00725232130.022
regulation of kinase activityGO:00435492490.022
neural tube developmentGO:00219151600.022
mapk cascadeGO:00001652810.022
cellular response to molecule of bacterial originGO:0071219830.022
apoptotic signaling pathwayGO:00971903060.022
intracellular protein transportGO:00068862040.021
positive regulation of secretionGO:00510471300.021
t cell activationGO:00421102890.021
protein ubiquitinationGO:00165671710.021
embryonic epithelial tube formationGO:00018381300.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
negative regulation of cellular component organizationGO:00511291940.021
purine nucleoside catabolic processGO:00061522050.021
modification dependent macromolecule catabolic processGO:00436321330.021
positive regulation of cytokine productionGO:00018191740.021
regulation of protein serine threonine kinase activityGO:00719001570.021
response to molecule of bacterial originGO:00022371430.021
acetylcholine transportGO:001587020.021
neuron projection guidanceGO:00974851410.021
Zebrafish Mouse
positive regulation of programmed cell deathGO:00430682180.020
camera type eye developmentGO:00430102660.020
response to organonitrogen compoundGO:00102432460.020
regulation of peptidase activityGO:0052547960.020
neuron migrationGO:00017641220.020
gtp catabolic processGO:00061841430.020
regulation of membrane potentialGO:00423911920.020
appendage developmentGO:00487361660.020
Zebrafish
regulation of establishment of protein localizationGO:00702011810.020
regulation of defense responseGO:00313472330.020
regulation of protein transportGO:00512231630.020
gtp metabolic processGO:00460391440.020
proteolysis involved in cellular protein catabolic processGO:00516031470.020
nucleoside phosphate catabolic processGO:19012922220.020
lateral inhibitionGO:004633110.020
positive regulation of protein phosphorylationGO:00019342420.019
positive regulation of secretion by cellGO:19035321140.019
embryonic organ morphogenesisGO:00485622760.019
negative regulation of protein modification processGO:00314001630.019
multicellular organismal homeostasisGO:00488711640.019
peptidyl tyrosine phosphorylationGO:00181081430.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
ion transmembrane transportGO:00342203610.019
regulation of cell migrationGO:00303342190.019
endocytosisGO:00068971680.018
dna metabolic processGO:00062593030.018
anion transmembrane transportGO:0098656710.018
tube formationGO:00351481400.018
purine nucleotide catabolic processGO:00061952110.018
epithelial tube formationGO:00721751300.018
regulation of cellular response to stressGO:00801351590.018
sensory perceptionGO:00076002450.018
cellular response to biotic stimulusGO:0071216920.018
maintenance of locationGO:0051235890.018
oxidation reduction processGO:00551143420.018
cytokine productionGO:00018163190.018
negative regulation of protein phosphorylationGO:00019331260.018
glycoprotein metabolic processGO:00091001160.018
stem cell differentiationGO:00488632680.017
anatomical structure homeostasisGO:00602491450.017
regulation of cellular response to growth factor stimulusGO:0090287820.017
Zebrafish
cellular protein catabolic processGO:00442571550.017
tissue homeostasisGO:00018941150.017
ribonucleoside metabolic processGO:00091192450.017
digestive system developmentGO:00551232000.017
cation transmembrane transportGO:00986552660.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.017
carbohydrate derivative biosynthetic processGO:19011371830.017
response to radiationGO:00093141650.017
cellular response to dna damage stimulusGO:00069742070.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.017
regulation of cell projection organizationGO:00313442060.017
Zebrafish
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.017
positive regulation of cell activationGO:00508671580.017
regulation of nucleotide catabolic processGO:00308111220.017
lymphocyte differentiationGO:00300982420.017
positive regulation of macroautophagyGO:001623930.017
gland developmentGO:00487323300.017
lipid localizationGO:00108761260.016
epithelial tube morphogenesisGO:00605623030.016
protein targetingGO:00066051430.016
circulatory system processGO:00030131970.016
negative regulation of cell growthGO:0030308440.016
response to sterolGO:003631440.016
asymmetric stem cell divisionGO:009872230.016
cell growthGO:00160491300.016
Zebrafish
positive regulation of protein transportGO:0051222930.016
cognitionGO:00508901490.016
nucleocytoplasmic transportGO:00069131390.016
positive regulation of cell developmentGO:00107202370.016
protein secretionGO:00093061110.016
regulation of neuron differentiationGO:00456642810.016
Zebrafish
regulation of cytokine productionGO:00018172660.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
protein importGO:00170381010.016
sensory organ morphogenesisGO:00905962420.016
skeletal system morphogenesisGO:00487052030.015
regulation of interleukin 8 productionGO:003267730.015
guanosine containing compound metabolic processGO:19010681440.015
regulation of secretion by cellGO:19035302490.015
negative regulation of synapse assemblyGO:005196430.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
positive regulation of apoptotic signaling pathwayGO:2001235950.015
cell type specific apoptotic processGO:00972852680.015
locomotory behaviorGO:00076261950.015
regulation of nucleoside metabolic processGO:00091181300.015
telencephalon developmentGO:00215371860.015
Mouse
negative regulation of hydrolase activityGO:0051346710.015
glycoprotein biosynthetic processGO:0009101890.015
engulfment of apoptotic cellGO:004365230.015
positive regulation of transferase activityGO:00513471670.015
negative regulation of phosphorylationGO:00423261660.015
endomembrane system organizationGO:00102561470.015
acetate ester transportGO:190137420.015
primary neural tube formationGO:0014020950.015
multi multicellular organism processGO:00447061090.015
organelle assemblyGO:00709251770.015
wnt signaling pathwayGO:00160551880.015
Fly
central nervous system neuron differentiationGO:00219531620.015
cellular response to lipopolysaccharideGO:0071222770.015
peptidyl amino acid modificationGO:00181933360.015
regulation of leukocyte differentiationGO:19021051590.014
t cell differentiationGO:00302171740.014
regulation of vesicle mediated transportGO:00606271390.014
angiogenesisGO:00015252010.014
response to organic cyclic compoundGO:00140701980.014
cell substrate adhesionGO:00315891300.014
regulation of feeding behaviorGO:006025930.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.014
leukocyte migrationGO:00509001240.014
positive regulation of protein kinase activityGO:00458601440.014
regulation of cell sizeGO:0008361720.014
Zebrafish
semaphorin plexin signaling pathway involved in bone trabecula morphogenesisGO:190022020.014
regulation of protein processingGO:0070613960.014
asymmetric neuroblast divisionGO:005505910.014
epithelial cell developmentGO:00020641590.014
protein localization to membraneGO:00726571080.014
fat cell differentiationGO:00454441600.014
photoreceptor cell differentiationGO:0046530520.014
regulation of purine nucleotide catabolic processGO:00331211220.014
reactive nitrogen species metabolic processGO:200105700.014
positive regulation of gtp catabolic processGO:0033126850.014
muscle tissue developmentGO:00605373080.014
synaptic transmissionGO:00072683290.014
fibrinolysisGO:004273030.013
developmental growth involved in morphogenesisGO:00605601380.013
Zebrafish
regulation of gtp catabolic processGO:00331241130.013
regulation of body fluid levelsGO:00508781620.013
peptidyl tyrosine modificationGO:00182121450.013
positive regulation of kinase activityGO:00336741550.013
glycerophospholipid metabolic processGO:0006650710.013
guanosine containing compound catabolic processGO:19010691440.013
regulation of intracellular transportGO:00323861590.013
regulation of cytoplasmic transportGO:19036491120.013
striated muscle tissue developmentGO:00147062930.013
hindbrain developmentGO:00309021280.013
regulation of lymphocyte proliferationGO:00506701170.013
connective tissue developmentGO:00614481790.013
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
Zebrafish
modification by symbiont of host morphology or physiologyGO:004400340.013
regulation of peptidyl tyrosine phosphorylationGO:0050730930.013
regulation of mapk cascadeGO:00434082480.013
extracellular matrix organizationGO:00301981470.013
Zebrafish
leukocyte homeostasisGO:0001776790.013
mesenchymal cell developmentGO:0014031930.013
retina development in camera type eyeGO:00600411190.013
regulation of ossificationGO:00302781120.013
protein localization to organelleGO:00333651850.013
mitochondrion distributionGO:004831140.013
regulation of ras protein signal transductionGO:00465781140.013
regulation of anatomical structure sizeGO:00900661780.013
Zebrafish
inorganic ion transmembrane transportGO:00986602340.013
production of molecular mediator of immune responseGO:00024401030.013
gastrulationGO:00073691160.013
mitochondrion organizationGO:00070051340.013
peripheral nervous system developmentGO:0007422530.013
mesenchymal cell differentiationGO:00487621070.013
adaptive immune responseGO:00022501550.013
cellular ion homeostasisGO:00068731650.013
morphogenesis of a branching epitheliumGO:00611381930.013
reactive oxygen species biosynthetic processGO:190340980.012
cellular response to organonitrogen compoundGO:00714171450.012
posttranscriptional regulation of gene expressionGO:00106081550.012
actin cytoskeleton organizationGO:00300362200.012
response to lipopolysaccharideGO:00324961280.012
dephosphorylationGO:00163111290.012
neural tube formationGO:00018411080.012
establishment of protein localization to organelleGO:00725941180.012
g protein coupled receptor signaling pathwayGO:00071862430.012
respiratory tube developmentGO:00303231670.012
negative regulation of proteolysisGO:0045861740.012
learning or memoryGO:00076111480.012
regulation of cytoskeleton organizationGO:00514931220.012
positive regulation of nervous system developmentGO:00519622210.012
gliogenesisGO:00420631410.012
regulation of engulfment of apoptotic cellGO:190107420.012
neural tube closureGO:0001843900.012
inorganic cation transmembrane transportGO:00986622070.012
digestive tract morphogenesisGO:00485461470.012
nuclear divisionGO:00002801580.012
ear developmentGO:00435832000.012
respiratory system developmentGO:00605411900.012
regulation of cell growthGO:0001558910.012
Zebrafish
embryonic limb morphogenesisGO:00303261260.012
protein import into nucleusGO:0006606950.012
single organism cell adhesionGO:00986021560.012
regulation of cell adhesionGO:00301551540.012
stem cell maintenanceGO:00198271300.012
heart morphogenesisGO:00030071780.012
plasma membrane organizationGO:0007009900.012
regulation of intracellular protein transportGO:0033157820.012
cellular response to lipidGO:00713961450.012
negative regulation of glial cell proliferationGO:006025340.012
nitrogen compound transportGO:00717052710.012
interferon gamma productionGO:0032609670.012
regulation of endopeptidase activityGO:0052548890.012
cellular chemical homeostasisGO:00550822150.012
divalent inorganic cation transportGO:00725111780.012
leukocyte proliferationGO:00706611720.012
renal system developmentGO:00720012250.012
regulation of t cell activationGO:00508631700.012
regulation of protein modification by small protein conjugation or removalGO:1903320570.012
neural retina developmentGO:0003407410.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
positive regulation of leukocyte differentiationGO:1902107860.011
negative regulation of cell cycleGO:00457861230.011
cellular lipid metabolic processGO:00442553230.011
innate immune responseGO:00450871570.011
interleukin 8 productionGO:003263740.011
developmental cell growthGO:0048588840.011
Zebrafish
positive regulation of peptidase activityGO:0010952490.011
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.011
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.011
recognition of apoptotic cellGO:004365430.011
axon guidanceGO:00074111410.011
Zebrafish Mouse
protein localization to nucleusGO:00345041210.011
negative regulation of cellular catabolic processGO:0031330470.011
proteasomal protein catabolic processGO:0010498980.011
receptor localization to synapseGO:009712040.011
reactive oxygen species metabolic processGO:0072593840.011
norepinephrine transportGO:001587420.011
microtubule based processGO:00070172360.011
meiotic nuclear divisionGO:00071261150.011
calcium ion homeostasisGO:00550741270.011
regulation of protein targetingGO:1903533610.011
heparin biosynthetic processGO:003021020.011
Fly
regulation of cysteine type endopeptidase activityGO:2000116650.011
regulation of secretionGO:00510462740.011
anion transportGO:00068201770.011
exocytosisGO:00068871210.011
protein localization to synapseGO:0035418110.011
regulation of cellular component biogenesisGO:00440871810.011
synapse organizationGO:00508081250.011
negative regulation of cellular response to growth factor stimulusGO:0090288460.011
regulation of protein maturationGO:1903317960.011
response to light stimulusGO:00094161350.011
organophosphate biosynthetic processGO:00904071220.011
cell fate commitmentGO:00451652100.011
lipid transportGO:0006869980.011
positive regulation of immune effector processGO:00026991070.011
glial cell differentiationGO:00100011310.011
skin developmentGO:00435882200.011
ribonucleoside bisphosphate metabolic processGO:003387590.011
positive regulation of gtpase activityGO:0043547850.011
lung developmentGO:00303241640.011
myeloid leukocyte differentiationGO:00025731190.011
positive regulation of cell motilityGO:20001471160.011
skeletal muscle organ developmentGO:00605381630.010
sequestering of metal ionGO:0051238190.010
regulation of extent of cell growthGO:0061387520.010
Zebrafish
action potentialGO:0001508780.010
homeostasis of number of cellsGO:00488722100.010
canonical wnt signaling pathwayGO:00600701300.010
regulation of rho protein signal transductionGO:0035023710.010
organic hydroxy compound metabolic processGO:19016152030.010
regulation of protein bindingGO:0043393600.010
myotube differentiationGO:00149021050.010
germ cell developmentGO:00072811850.010
negative regulation of protein processingGO:0010955790.010
tissue migrationGO:0090130680.010
metencephalon developmentGO:0022037890.010
regulation of blood pressureGO:0008217930.010
macromolecule glycosylationGO:0043413550.010
regulation of nucleocytoplasmic transportGO:0046822730.010
midgut developmentGO:000749440.010
norepinephrine secretionGO:004824320.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.010
regionalizationGO:00030023370.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
cellular metal ion homeostasisGO:00068751510.010
organelle fissionGO:00482851700.010
male gamete generationGO:00482322850.010

Ext2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.026
disease of metabolismDOID:001466700.026
disease of anatomical entityDOID:700.023
immune system diseaseDOID:291400.023
nervous system diseaseDOID:86300.022
central nervous system diseaseDOID:33100.022
connective tissue diseaseDOID:6500.017
musculoskeletal system diseaseDOID:1700.017
hematopoietic system diseaseDOID:7400.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.012
cancerDOID:16200.012
bone diseaseDOID:008000100.010