Mus musculus

12 known processes

Defb8

defensin beta 8

(Aliases: Defr1,BD-8)

Defb8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180840.156
transmembrane transportGO:00550854120.145
ion transmembrane transportGO:00342203610.117
regulation of cellular amino acid metabolic processGO:000652150.099
cytokine productionGO:00018163190.084
regulation of cytokine productionGO:00018172660.073
cation transmembrane transportGO:00986552660.071
amine metabolic processGO:0009308450.070
cation transportGO:00068123990.064
cellular lipid metabolic processGO:00442553230.062
monocarboxylic acid metabolic processGO:00327871910.062
immune effector processGO:00022523210.060
extracellular matrix organizationGO:00301981470.058
cellular amino acid metabolic processGO:00065201030.058
positive regulation of secretionGO:00510471300.057
regulation of cellular ketone metabolic processGO:0010565660.055
regulation of cell activationGO:00508652890.053
skeletal system developmentGO:00015013560.051
lymphocyte differentiationGO:00300982420.051
connective tissue developmentGO:00614481790.049
inflammatory responseGO:00069542440.049
protein maturationGO:00516041760.048
muscle tissue developmentGO:00605373080.047
organic hydroxy compound metabolic processGO:19016152030.047
negative regulation of immune system processGO:00026832090.046
regulation of defense responseGO:00313472330.046
response to organonitrogen compoundGO:00102432460.046
macromolecule catabolic processGO:00090572810.046
camera type eye developmentGO:00430102660.044
cellular homeostasisGO:00197252400.043
multi multicellular organism processGO:00447061090.043
embryonic organ morphogenesisGO:00485622760.043
nitrogen compound transportGO:00717052710.043
extracellular structure organizationGO:00430621480.042
male gamete generationGO:00482322850.042
regulation of protein transportGO:00512231630.041
striated muscle tissue developmentGO:00147062930.041
embryonic placenta developmentGO:0001892980.039
regulation of establishment of protein localizationGO:00702011810.039
defense response to other organismGO:00985421970.038
positive regulation of defense responseGO:00313491240.038
positive regulation of cytokine productionGO:00018191740.038
t cell activationGO:00421102890.037
action potentialGO:0001508780.037
placenta developmentGO:00018901400.036
chemotaxisGO:00069352470.036
kidney developmentGO:00018222130.036
skin developmentGO:00435882200.036
cellular amine metabolic processGO:0044106440.035
regulation of response to woundingGO:19030341890.035
steroid metabolic processGO:00082021190.035
regulation of cell migrationGO:00303342190.035
regulation of protein localizationGO:00328802310.035
regulation of lymphocyte activationGO:00512492400.034
small gtpase mediated signal transductionGO:0007264970.034
inorganic cation transmembrane transportGO:00986622070.034
stem cell proliferationGO:00720891170.034
defense response to bacteriumGO:00427421190.034
epithelial cell developmentGO:00020641590.034
response to organic cyclic compoundGO:00140701980.034
carbohydrate derivative biosynthetic processGO:19011371830.033
organonitrogen compound biosynthetic processGO:19015661920.033
regulation of secretionGO:00510462740.032
regulation of epithelial cell proliferationGO:00506781410.032
regulation of membrane potentialGO:00423911920.031
anion transportGO:00068201770.031
innate immune responseGO:00450871570.031
protein processingGO:00164851630.031
urogenital system developmentGO:00016552610.031
response to molecule of bacterial originGO:00022371430.031
negative regulation of blood vessel endothelial cell migrationGO:004353730.030
positive regulation of cellular amine metabolic processGO:003324050.030
regulation of kinase activityGO:00435492490.030
cellular response to lipidGO:00713961450.029
blood vessel morphogenesisGO:00485142850.029
epithelial tube morphogenesisGO:00605623030.029
homeostasis of number of cellsGO:00488722100.029
locomotory behaviorGO:00076261950.029
regulation of cell cycleGO:00517262810.029
negative regulation of response to woundingGO:1903035770.028
morphogenesis of a branching epitheliumGO:00611381930.028
positive regulation of cell developmentGO:00107202370.028
epithelial cell proliferationGO:00506731740.028
regulation of cellular amine metabolic processGO:0033238200.028
striated muscle cell developmentGO:00550021250.027
regulation of system processGO:00440572000.027
spermatogenesisGO:00072832840.027
ribose phosphate metabolic processGO:00196932910.027
calcium ion transportGO:00068161590.027
organic hydroxy compound biosynthetic processGO:1901617770.027
inorganic ion transmembrane transportGO:00986602340.027
response to lipopolysaccharideGO:00324961280.027
negative regulation of cellular protein metabolic processGO:00322692470.026
purine nucleotide metabolic processGO:00061633020.026
cellular chemical homeostasisGO:00550822150.026
glycoprotein biosynthetic processGO:0009101890.026
cellular macromolecule catabolic processGO:00442652060.026
reactive oxygen species metabolic processGO:0072593840.026
cellular response to molecule of bacterial originGO:0071219830.025
anion transmembrane transportGO:0098656710.025
muscle cell differentiationGO:00426922610.025
t cell differentiationGO:00302171740.025
negative regulation of cellular amino acid metabolic processGO:004576300.025
regulation of homeostatic processGO:00328441820.025
negative regulation of protein metabolic processGO:00512482820.025
alcohol metabolic processGO:00060661160.025
circulatory system processGO:00030131970.024
fat cell differentiationGO:00454441600.024
negative regulation of cell developmentGO:00107211690.024
regulation of secretion by cellGO:19035302490.024
angiogenesisGO:00015252010.024
developmental maturationGO:00217001930.024
transmission of nerve impulseGO:0019226760.024
ear developmentGO:00435832000.024
nucleoside phosphate metabolic processGO:00067533380.024
positive regulation of secretion by cellGO:19035321140.023
regulation of cell motilityGO:20001452360.023
negative regulation of phosphorus metabolic processGO:00105631840.023
peptidyl amino acid modificationGO:00181933360.023
positive regulation of protein phosphorylationGO:00019342420.023
ossificationGO:00015032160.023
regulation of body fluid levelsGO:00508781620.023
sensory organ morphogenesisGO:00905962420.023
negative regulation of cellular amine metabolic processGO:003323910.023
positive regulation of transferase activityGO:00513471670.022
regulation of vesicle mediated transportGO:00606271390.022
defense response to gram negative bacteriumGO:0050829280.022
Mouse
regulation of muscle tissue developmentGO:1901861970.022
mapk cascadeGO:00001652810.022
purine containing compound metabolic processGO:00725213110.022
leukocyte differentiationGO:00025213420.022
cellular response to organonitrogen compoundGO:00714171450.022
protein modification by small protein conjugation or removalGO:00706472070.022
cellular response to biotic stimulusGO:0071216920.022
monosaccharide metabolic processGO:00059961060.022
cellular response to organic cyclic compoundGO:0071407870.022
aromatic compound catabolic processGO:00194392860.022
regulation of hormone levelsGO:00108172110.021
immune response activating signal transductionGO:00027571160.021
organonitrogen compound catabolic processGO:19015652640.021
tissue remodelingGO:00487711020.021
protein catabolic processGO:00301632210.021
regulation of vasculature developmentGO:1901342880.021
regulation of lipid metabolic processGO:00192161180.021
myotube differentiationGO:00149021050.021
hematopoietic progenitor cell differentiationGO:00022441430.021
regulation of reactive oxygen species metabolic processGO:2000377400.021
l alpha amino acid transmembrane transportGO:1902475230.021
g protein coupled receptor signaling pathwayGO:00071862430.021
organic acid transportGO:00158491010.021
negative regulation of cell activationGO:00508661110.020
oxidation reduction processGO:00551143420.020
neural precursor cell proliferationGO:00613511210.020
regionalizationGO:00030023370.020
muscle system processGO:00030121410.020
positive regulation of leukocyte proliferationGO:0070665730.020
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.020
glycoprotein metabolic processGO:00091001160.020
membrane organizationGO:00610242450.020
activation of immune responseGO:00022531380.020
nucleotide metabolic processGO:00091173320.020
protein modification by small protein conjugationGO:00324461870.020
organic cyclic compound catabolic processGO:19013612950.020
positive regulation of stem cell proliferationGO:2000648590.020
lipid biosynthetic processGO:00086101790.020
divalent inorganic cation transportGO:00725111780.019
skeletal system morphogenesisGO:00487052030.019
response to nutrient levelsGO:00316671090.019
regulation of organelle organizationGO:00330432890.019
regulation of ion transportGO:00432692150.019
cytoplasmic transportGO:00164822340.019
symbiosis encompassing mutualism through parasitismGO:0044403830.019
negative regulation of nik nf kappab signalingGO:190122320.019
positive regulation of immune effector processGO:00026991070.019
multicellular organismal signalingGO:0035637910.019
positive regulation of innate immune responseGO:0045089800.019
immune response regulating signaling pathwayGO:00027641250.019
regulation of protein secretionGO:0050708820.019
cellular response to nutrient levelsGO:0031669640.019
regulation of mitotic cell cycleGO:00073461260.019
negative regulation of cellular component organizationGO:00511291940.019
cellular carbohydrate metabolic processGO:00442621190.019
nucleobase containing small molecule metabolic processGO:00550863520.018
regulation of anatomical structure sizeGO:00900661780.018
positive regulation of cell motilityGO:20001471160.018
cellular response to lipopolysaccharideGO:0071222770.018
interferon gamma productionGO:0032609670.018
regulation of cell growthGO:0001558910.018
cell fate commitmentGO:00451652100.018
carbohydrate metabolic processGO:00059752300.018
regulation of ossificationGO:00302781120.018
regulation of leukocyte proliferationGO:00706631210.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
regulation of hydrolase activityGO:00513362460.018
purine ribonucleotide metabolic processGO:00091502900.018
cellular protein complex assemblyGO:00436231160.018
posttranscriptional regulation of gene expressionGO:00106081550.018
skeletal muscle organ developmentGO:00605381630.018
regulation of transferase activityGO:00513382630.018
positive regulation of protein modification processGO:00314012990.018
organic anion transportGO:00157111370.018
positive regulation of lymphocyte activationGO:00512511400.018
negative regulation of cell proliferationGO:00082852960.017
single organism cell adhesionGO:00986021560.017
interleukin 6 productionGO:0032635580.017
germ cell developmentGO:00072811850.017
neuronal action potentialGO:0019228540.017
cell growthGO:00160491300.017
coagulationGO:0050817780.017
blood circulationGO:00080151950.017
negative regulation of phosphate metabolic processGO:00459361840.017
glycerolipid metabolic processGO:00464861220.017
developmental growth involved in morphogenesisGO:00605601380.017
regulation of interferon gamma productionGO:0032649570.017
tumor necrosis factor productionGO:0032640500.017
negative regulation of cell cycleGO:00457861230.017
regulation of transmembrane transportGO:00347621280.016
ribonucleotide metabolic processGO:00092592910.016
respiratory system developmentGO:00605411900.016
intracellular protein transportGO:00068862040.016
stem cell developmentGO:00488642190.016
regulation of mapk cascadeGO:00434082480.016
lymphocyte mediated immunityGO:00024491390.016
cellular alcohol biosynthetic processGO:004410830.016
calcitriol biosynthetic process from calciolGO:003637830.016
protein ubiquitinationGO:00165671710.016
ensheathment of neuronsGO:0007272760.016
negative regulation of phosphorylationGO:00423261660.016
cell maturationGO:00484691270.016
leukocyte proliferationGO:00706611720.016
renal system developmentGO:00720012250.016
regulation of cell projection organizationGO:00313442060.016
regulation of protein kinase activityGO:00458592320.016
rho protein signal transductionGO:0007266320.016
blastocyst developmentGO:0001824800.016
cellular ion homeostasisGO:00068731650.016
positive regulation of nervous system developmentGO:00519622210.016
regulation of inflammatory responseGO:00507271470.015
cardiac muscle tissue developmentGO:00487381300.015
regulation of fat cell differentiationGO:0045598810.015
negative regulation of cytokine productionGO:0001818840.015
regulation of microvillus organizationGO:003253030.015
interspecies interaction between organismsGO:0044419830.015
wound healingGO:00420601570.015
ameboidal type cell migrationGO:00016671280.015
synapse organizationGO:00508081250.015
positive regulation of angiogenesisGO:0045766460.015
amino acid transmembrane transportGO:0003333370.015
positive regulation of epithelial cell proliferationGO:0050679680.015
cellular response to hormone stimulusGO:00328701500.015
establishment of blood nerve barrierGO:000806530.015
positive regulation of keratinocyte proliferationGO:001083840.015
negative regulation of molecular functionGO:00440922580.015
negative regulation of protein processingGO:0010955790.015
positive regulation of cell cycleGO:0045787920.015
negative regulation of defense responseGO:0031348770.015
glucose homeostasisGO:00425931280.015
regulation of bindingGO:00510981110.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
purine containing compound catabolic processGO:00725232130.015
cellular nitrogen compound catabolic processGO:00442702800.015
lymphocyte proliferationGO:00466511640.015
diacylglycerol biosynthetic processGO:000665120.014
sulfur compound metabolic processGO:00067901000.014
proteoglycan metabolic processGO:0006029380.014
transforming growth factor beta secretionGO:003804410.014
heart processGO:0003015940.014
bone developmentGO:00603481200.014
myelinationGO:0042552740.014
cellular response to cytokine stimulusGO:00713451890.014
endocytosisGO:00068971680.014
stem cell differentiationGO:00488632680.014
muscle cell developmentGO:00550011330.014
leukocyte mediated immunityGO:00024431740.014
regulation of neuron differentiationGO:00456642810.014
primary neural tube formationGO:0014020950.014
regulation of neural precursor cell proliferationGO:2000177700.014
leukocyte migrationGO:00509001240.014
chromatin modificationGO:00165681870.014
gland developmentGO:00487323300.014
negative regulation of endothelial cell migrationGO:001059640.014
lipid localizationGO:00108761260.014
regulation of angiogenesisGO:0045765810.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
modification dependent macromolecule catabolic processGO:00436321330.014
embryonic epithelial tube formationGO:00018381300.013
cellular response to external stimulusGO:0071496880.013
cardiac chamber morphogenesisGO:0003206930.013
cellular metal ion homeostasisGO:00068751510.013
amino acid transportGO:0006865610.013
positive regulation of interferon gamma productionGO:0032729390.013
regulation of cellular component biogenesisGO:00440871810.013
l amino acid transportGO:0015807320.013
cell activation involved in immune responseGO:00022631260.013
axonogenesisGO:00074092740.013
aminoglycan metabolic processGO:0006022340.013
heart morphogenesisGO:00030071780.013
regulation of proteolysisGO:00301621640.013
positive regulation of hydrolase activityGO:00513451480.013
epidermis developmentGO:00085441870.013
kidney epithelium developmentGO:00720731210.013
heart contractionGO:0060047930.013
mitotic cell cycleGO:00002781950.013
cell type specific apoptotic processGO:00972852680.013
hormone secretionGO:00468791280.013
synaptic transmissionGO:00072683290.013
small molecule catabolic processGO:0044282710.013
heterocycle catabolic processGO:00467002800.013
regulation of cellular catabolic processGO:00313292420.013
cellular response to carbohydrate stimulusGO:0071322500.013
ribonucleoside metabolic processGO:00091192450.013
embryonic skeletal system developmentGO:00487061200.013
cellular alcohol metabolic processGO:004410730.013
carboxylic acid transportGO:00469421000.013
regulation of cell cycle processGO:00105641600.013
positive regulation of cell activationGO:00508671580.013
regulation of blood vessel sizeGO:0050880560.013
regulation of protein catabolic processGO:00421761080.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
fertilizationGO:00095661270.013
dna metabolic processGO:00062593030.013
positive regulation of cell migrationGO:00303351090.013
organophosphate biosynthetic processGO:00904071220.013
myoblast differentiationGO:0045445520.013
organic hydroxy compound transportGO:0015850930.013
regulation of endopeptidase activityGO:0052548890.013
palate developmentGO:0060021760.013
negative regulation of inflammatory responseGO:0050728610.013
midgut developmentGO:000749440.013
tumor necrosis factor superfamily cytokine productionGO:0071706510.013
ribonucleotide catabolic processGO:00092612080.012
regulation of ketone biosynthetic processGO:001056620.012
cell differentiation involved in embryonic placenta developmentGO:0060706260.012
protein secretionGO:00093061110.012
glial cell differentiationGO:00100011310.012
mesenchymal cell developmentGO:0014031930.012
fat soluble vitamin biosynthetic processGO:004236240.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
compound eye developmentGO:004874910.012
chromatin organizationGO:00063252060.012
protein localization to nucleusGO:00345041210.012
conditioned taste aversionGO:000166140.012
negative regulation of endopeptidase activityGO:0010951440.012
regulation of protein maturationGO:1903317960.012
response to inorganic substanceGO:0010035960.012
response to starvationGO:0042594650.012
leukocyte activation involved in immune responseGO:00023661260.012
cytokine metabolic processGO:0042107710.012
morphogenesis of a branching structureGO:00017632030.012
response to extracellular stimulusGO:00099911270.012
regulation of apoptotic signaling pathwayGO:20012331970.012
ovulation cycleGO:0042698590.012
norepinephrine transportGO:001587420.012
positive regulation of mapk cascadeGO:00434101700.012
regulation of lymphocyte mediated immunityGO:0002706840.012
divalent metal ion transportGO:00708381720.012
myeloid cell homeostasisGO:00022621140.012
nucleoside phosphate catabolic processGO:19012922220.012
sensory perceptionGO:00076002450.012
regulation of phospholipase a2 activityGO:003242930.012
positive regulation of secondary heart field cardioblast proliferationGO:007251340.012
adult behaviorGO:00305341350.012
ras protein signal transductionGO:0007265770.012
regulation of t cell activationGO:00508631700.012
positive regulation of protein transportGO:0051222930.012
biomineral tissue developmentGO:0031214640.012
myeloid cell differentiationGO:00300992330.012
divalent inorganic cation homeostasisGO:00725071380.012
forebrain developmentGO:00309003020.012
regulation of feeding behaviorGO:006025930.012
blood coagulationGO:0007596760.012
reactive nitrogen species metabolic processGO:200105700.012
t cell proliferationGO:00420981200.012
negative regulation of proteolysisGO:0045861740.012
acylglycerol metabolic processGO:0006639550.011
pancreas developmentGO:0031016570.011
regulation of protein oligomerizationGO:003245940.011
female sex determinationGO:003023710.011
regulation of leukocyte mediated immunityGO:00027031040.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
positive regulation of proteolysisGO:0045862850.011
negative regulation of immune effector processGO:0002698550.011
regulation of myotube differentiationGO:0010830620.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
smoothened signaling pathwayGO:00072241050.011
endothelium developmentGO:0003158450.011
odontogenesisGO:0042476780.011
blood vessel remodelingGO:0001974330.011
generation of precursor metabolites and energyGO:00060911030.011
regulation of protein processingGO:0070613960.011
regulation of cell adhesionGO:00301551540.011
response to steroid hormoneGO:0048545560.011
regulation of stem cell proliferationGO:0072091780.011
nucleoside triphosphate metabolic processGO:00091412300.011
spermatid differentiationGO:00485151150.011
regulation of tube sizeGO:0035150570.011
neuron neuron synaptic transmissionGO:0007270690.011
regulation of multi organism processGO:00439001110.011
regulation of action potentialGO:009890040.011
somitogenesisGO:0001756690.011
immunoglobulin productionGO:0002377730.011
limb morphogenesisGO:00351081490.011
cellular response to fluid shear stressGO:007149840.011
regulation of cellular response to stressGO:00801351590.011
carbohydrate derivative catabolic processGO:19011362310.011
negative regulation of multi organism processGO:0043901680.011
peptide transportGO:00158331330.011
positive regulation of protein oligomerizationGO:003246140.011
nucleotide catabolic processGO:00091662170.011
alpha beta t cell activationGO:0046631910.011
proteasomal protein catabolic processGO:0010498980.011
multicellular organism growthGO:00352641610.011
regulation of cytokine secretionGO:0050707610.011
cellular response to acid chemicalGO:0071229680.011
mesodermal cell migrationGO:000807840.011
neural tube developmentGO:00219151600.011
cellular calcium ion homeostasisGO:00068741190.011
hair cycleGO:0042633900.011
mesangial cell differentiationGO:007200740.011
apoptotic signaling pathwayGO:00971903060.011
peptidyl tyrosine phosphorylationGO:00181081430.011
respiratory tube developmentGO:00303231670.011
regulation of striated muscle cell differentiationGO:0051153810.011
peptide hormone secretionGO:00300721090.011
negative regulation of mitotic cell cycleGO:0045930580.011
bmp signaling pathwayGO:0030509930.011
tube formationGO:00351481400.011
small molecule biosynthetic processGO:00442831320.011
regulation of t cell proliferationGO:0042129920.011
positive regulation of interleukin 8 productionGO:003275720.011
regulation of peptidase activityGO:0052547960.011
purine nucleoside metabolic processGO:00422782410.011
regulation of cellular component sizeGO:00325351210.011
erk1 and erk2 cascadeGO:0070371770.011
fatty acid metabolic processGO:00066311210.011
macromolecule glycosylationGO:0043413550.011
hormone metabolic processGO:0042445860.011
regulation of adaptive immune responseGO:0002819900.011
regulation of innate immune responseGO:0045088910.011
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.011
multi organism behaviorGO:0051705620.010
insulin secretionGO:0030073890.010
antimicrobial peptide biosynthetic processGO:000277720.010
actin cytoskeleton organizationGO:00300362200.010
regulation of wound healingGO:0061041400.010
regulation of peptidyl tyrosine phosphorylationGO:0050730930.010
pattern specification involved in metanephros developmentGO:007226840.010
negative regulation of intracellular signal transductionGO:19025321670.010
hemostasisGO:0007599780.010
regulation of testosterone biosynthetic processGO:200022420.010
digestive tract developmentGO:00485651900.010
morphogenesis of embryonic epitheliumGO:00163311590.010
cytokine biosynthetic processGO:0042089680.010
organic acid catabolic processGO:0016054510.010
somite developmentGO:0061053810.010
protein glycosylationGO:0006486550.010
neural tube formationGO:00018411080.010
androgen biosynthetic processGO:000670240.010
maintenance of locationGO:0051235890.010
proteoglycan biosynthetic processGO:0030166200.010
skeletal muscle cell differentiationGO:0035914660.010
mesonephric tubule developmentGO:0072164940.010
cartilage developmentGO:00512161400.010
carbohydrate homeostasisGO:00335001280.010
glycosaminoglycan metabolic processGO:0030203340.010
vitamin d3 metabolic processGO:007064030.010
tube closureGO:0060606910.010
nuclear transportGO:00511691390.010
organophosphate catabolic processGO:00464342320.010
b cell activationGO:00421131610.010
secondary alcohol metabolic processGO:190265230.010
regulation of carbohydrate metabolic processGO:0006109750.010
adaptive immune responseGO:00022501550.010
cell recognitionGO:0008037830.010
regulation of tumor necrosis factor productionGO:0032680490.010
cell adhesionGO:00071553290.010
ear morphogenesisGO:00424711180.010
energy derivation by oxidation of organic compoundsGO:0015980770.010
nucleocytoplasmic transportGO:00069131390.010
nuclear importGO:0051170950.010
nephron developmentGO:00720061090.010
purine ribonucleotide catabolic processGO:00091542080.010
detection of fungusGO:001604620.010

Defb8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
sensory system diseaseDOID:005015500.019
eye and adnexa diseaseDOID:149200.019
connective tissue diseaseDOID:6500.018
musculoskeletal system diseaseDOID:1700.018
bone diseaseDOID:008000100.016
lower respiratory tract diseaseDOID:005016100.015
respiratory system diseaseDOID:157900.015
eye diseaseDOID:561400.014
disease of metabolismDOID:001466700.013
bone development diseaseDOID:008000600.010