Mus musculus

13 known processes

Defb1

defensin beta 1

(Aliases: AW260221,BD-1)

Defb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.420
calcitriol biosynthetic process from calciolGO:003637830.414
drug metabolic processGO:001714440.320
oxidation reduction processGO:00551143420.318
medium chain fatty acid metabolic processGO:005179110.308
fatty acid metabolic processGO:00066311210.307
response to organic cyclic compoundGO:00140701980.261
inflammatory responseGO:00069542440.250
xenobiotic catabolic processGO:004217810.215
cellular amino acid metabolic processGO:00065201030.198
vitamin d3 metabolic processGO:007064030.193
regulation of hormone levelsGO:00108172110.178
cellular response to cytokine stimulusGO:00713451890.169
fat soluble vitamin biosynthetic processGO:004236240.156
cellular ketone metabolic processGO:0042180840.144
lipid biosynthetic processGO:00086101790.141
vitamin d biosynthetic processGO:004236830.141
organic hydroxy compound metabolic processGO:19016152030.140
regulation of secretionGO:00510462740.136
cellular alcohol metabolic processGO:004410730.127
unsaturated fatty acid metabolic processGO:0033559310.125
retinoic acid metabolic processGO:0042573120.122
exogenous drug catabolic processGO:004273810.119
amine metabolic processGO:0009308450.116
cellular alcohol biosynthetic processGO:004410830.116
sulfate assimilationGO:000010330.112
nitrogen compound transportGO:00717052710.107
secondary alcohol metabolic processGO:190265230.106
regulation of system processGO:00440572000.102
protein processingGO:00164851630.099
negative regulation of cellular protein metabolic processGO:00322692470.097
monocarboxylic acid metabolic processGO:00327871910.095
negative regulation of protein metabolic processGO:00512482820.087
regulation of body fluid levelsGO:00508781620.085
ion transmembrane transportGO:00342203610.080
naphthalene containing compound metabolic processGO:009042010.080
regulation of secretion by cellGO:19035302490.078
fatty acid derivative metabolic processGO:1901568330.077
regulation of response to woundingGO:19030341890.074
positive regulation of secretionGO:00510471300.072
steroid metabolic processGO:00082021190.071
cytokine productionGO:00018163190.069
anion transportGO:00068201770.065
response to organonitrogen compoundGO:00102432460.064
transmembrane transportGO:00550854120.062
cofactor metabolic processGO:0051186800.062
cellular response to molecule of bacterial originGO:0071219830.061
apoptotic signaling pathwayGO:00971903060.061
cytokine mediated signaling pathwayGO:00192211150.061
organic anion transportGO:00157111370.061
hematopoietic progenitor cell differentiationGO:00022441430.060
drug catabolic processGO:004273720.060
cellular response to cadmium ionGO:007127630.059
naphthalene metabolic processGO:001893110.059
cellular amine metabolic processGO:0044106440.058
cell cell junction organizationGO:0045216720.058
regulation of cellular amino acid metabolic processGO:000652150.058
response to inorganic substanceGO:0010035960.058
organic acid transportGO:00158491010.055
small molecule biosynthetic processGO:00442831320.054
regulation of lipid metabolic processGO:00192161180.054
epithelial cell proliferationGO:00506731740.053
wound healingGO:00420601570.053
protein maturationGO:00516041760.053
carboxylic acid biosynthetic processGO:0046394860.053
macromolecule catabolic processGO:00090572810.053
hormone metabolic processGO:0042445860.052
negative regulation of molecular functionGO:00440922580.051
regulation of cellular ketone metabolic processGO:0010565660.050
sulfur compound metabolic processGO:00067901000.050
hormone secretionGO:00468791280.050
regulation of cytokine productionGO:00018172660.050
regulation of reactive oxygen species metabolic processGO:2000377400.050
glycerolipid metabolic processGO:00464861220.049
intermediate filament based processGO:0045103270.049
toxin catabolic processGO:000940710.048
g protein coupled receptor signaling pathwayGO:00071862430.048
cellular response to inorganic substanceGO:0071241370.047
isoprenoid metabolic processGO:0006720290.046
epidermis developmentGO:00085441870.046
icosanoid metabolic processGO:0006690330.044
regulation of cell activationGO:00508652890.044
positive regulation of cellular amine metabolic processGO:003324050.043
terpenoid metabolic processGO:0006721250.043
lipid catabolic processGO:0016042690.043
peptide transportGO:00158331330.042
skin developmentGO:00435882200.042
water homeostasisGO:0030104270.042
regulation of inflammatory responseGO:00507271470.041
cellular response to lipidGO:00713961450.040
regulation of peptidase activityGO:0052547960.040
sensory perceptionGO:00076002450.039
leukocyte differentiationGO:00025213420.038
response to molecule of bacterial originGO:00022371430.038
response to lipopolysaccharideGO:00324961280.038
response to metal ionGO:0010038470.037
inorganic ion transmembrane transportGO:00986602340.036
regulation of cellular amine metabolic processGO:0033238200.036
regulation of blood pressureGO:0008217930.036
positive regulation of cytokine productionGO:00018191740.035
cellular homeostasisGO:00197252400.035
regulation of defense responseGO:00313472330.035
response to extracellular stimulusGO:00099911270.035
positive regulation of cellular amino acid metabolic processGO:004576430.033
cell type specific apoptotic processGO:00972852680.033
hair cycleGO:0042633900.033
keratinocyte differentiationGO:0030216480.033
defense response to bacteriumGO:00427421190.033
carboxylic acid transportGO:00469421000.032
oxidative demethylationGO:007098910.032
circulatory system processGO:00030131970.031
peptide hormone secretionGO:00300721090.031
organic acid biosynthetic processGO:0016053860.031
positive regulation of reactive oxygen species metabolic processGO:2000379110.030
regulation of protein processingGO:0070613960.030
cation transportGO:00068123990.030
response to nutrient levelsGO:00316671090.030
regulation of ion transportGO:00432692150.029
spermatogenesisGO:00072832840.029
muscle contractionGO:00069361010.029
regulation of protein localizationGO:00328802310.029
regulation of anatomical structure sizeGO:00900661780.029
inorganic cation transmembrane transportGO:00986622070.029
long chain fatty acid metabolic processGO:0001676260.028
cell junction organizationGO:0034330770.028
cofactor transportGO:005118140.028
regulation of blood vessel sizeGO:0050880560.028
neutral lipid metabolic processGO:0006638570.028
hexose metabolic processGO:0019318980.027
response to acid chemicalGO:00011011110.027
regulation of hormone secretionGO:0046883880.027
progesterone metabolic processGO:004244840.027
molting cycleGO:0042303900.027
monosaccharide metabolic processGO:00059961060.026
organonitrogen compound biosynthetic processGO:19015661920.026
regulation of epithelial cell proliferationGO:00506781410.026
intermediate filament cytoskeleton organizationGO:0045104260.025
diterpenoid metabolic processGO:0016101240.025
embryonic placenta developmentGO:0001892980.025
regulation of endopeptidase activityGO:0052548890.025
male gamete generationGO:00482322850.025
alcohol metabolic processGO:00060661160.025
protein catabolic processGO:00301632210.025
cellular response to hormone stimulusGO:00328701500.025
cellular response to lipopolysaccharideGO:0071222770.024
alpha amino acid metabolic processGO:1901605590.024
multicellular organismal water homeostasisGO:0050891230.024
endocrine processGO:0050886390.024
protein modification by small protein conjugationGO:00324461870.024
negative regulation of lipid metabolic processGO:0045833300.024
sphingolipid metabolic processGO:0006665450.024
dephosphorylationGO:00163111290.024
developmental maturationGO:00217001930.024
positive regulation of steroid hormone secretionGO:200083320.024
negative regulation of protein processingGO:0010955790.024
negative regulation of hydrolase activityGO:0051346710.024
single organism cell adhesionGO:00986021560.023
glucose metabolic processGO:0006006920.023
negative regulation of protein modification processGO:00314001630.023
organic hydroxy compound biosynthetic processGO:1901617770.023
amide transportGO:00428861380.023
negative regulation of immune system processGO:00026832090.023
negative regulation of protein maturationGO:1903318790.023
reactive oxygen species metabolic processGO:0072593840.023
blood coagulationGO:0007596760.023
vitamin transmembrane transportGO:003546140.023
negative regulation of cell proliferationGO:00082852960.023
sensory perception of light stimulusGO:0050953540.023
response to radiationGO:00093141650.023
intermediate filament organizationGO:0045109150.023
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressureGO:000199830.023
anion transmembrane transportGO:0098656710.023
regulation of proteolysisGO:00301621640.022
cellular response to biotic stimulusGO:0071216920.022
protein secretionGO:00093061110.022
regulation of establishment of protein localizationGO:00702011810.022
tetrapyrrole metabolic processGO:0033013220.022
retinoid metabolic processGO:0001523240.022
arachidonic acid metabolic processGO:0019369140.022
regulation of hydrolase activityGO:00513362460.022
hair follicle developmentGO:0001942850.021
alcohol biosynthetic processGO:0046165430.021
peptidyl amino acid modificationGO:00181933360.021
regulation of protein transportGO:00512231630.021
exocytosisGO:00068871210.021
regulation of water loss via skinGO:0033561160.021
regulation of lymphocyte activationGO:00512492400.021
positive regulation of secretion by cellGO:19035321140.021
negative regulation of response to woundingGO:1903035770.021
positive regulation of estrogen secretionGO:200086310.021
immune effector processGO:00022523210.021
carbohydrate metabolic processGO:00059752300.021
regulation of protein kinase activityGO:00458592320.021
regulation of epidermis developmentGO:0045682330.020
membrane lipid metabolic processGO:0006643530.020
negative regulation of proteolysisGO:0045861740.020
vitamin metabolic processGO:0006766230.020
secondary metabolite catabolic processGO:009048710.020
placenta developmentGO:00018901400.020
response to alcoholGO:0097305480.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
protein modification by small protein conjugation or removalGO:00706472070.020
insulin secretionGO:0030073890.020
locomotory behaviorGO:00076261950.019
response to steroid hormoneGO:0048545560.019
peptide metabolic processGO:0006518460.019
sensory organ morphogenesisGO:00905962420.019
linoleic acid metabolic processGO:004365160.019
single organismal cell cell adhesionGO:00163371310.019
regulation of tube sizeGO:0035150570.019
regulation of estrogen secretionGO:200086110.019
negative regulation of endopeptidase activityGO:0010951440.019
monocarboxylic acid biosynthetic processGO:0072330610.019
cation transmembrane transportGO:00986552660.019
lipid homeostasisGO:0055088630.018
cellular amide metabolic processGO:0043603580.018
cellular response to organonitrogen compoundGO:00714171450.018
regulation of renal sodium excretionGO:003581330.018
transmission of nerve impulseGO:0019226760.018
regulation of kinase activityGO:00435492490.018
renal tubular secretionGO:009725420.018
defense response to other organismGO:00985421970.018
lipid localizationGO:00108761260.018
action potentialGO:0001508780.018
prostaglandin metabolic processGO:0006693110.018
cell junction assemblyGO:0034329520.018
triglyceride metabolic processGO:0006641510.018
urogenital system developmentGO:00016552610.018
small molecule catabolic processGO:0044282710.017
regulation of protein catabolic processGO:00421761080.017
peptide secretionGO:00027901140.017
cellular response to organic cyclic compoundGO:0071407870.017
regulation of t cell activationGO:00508631700.017
gland developmentGO:00487323300.017
cellular macromolecule catabolic processGO:00442652060.017
leukocyte mediated immunityGO:00024431740.017
blood circulationGO:00080151950.017
multi multicellular organism processGO:00447061090.017
glucose homeostasisGO:00425931280.017
generation of precursor metabolites and energyGO:00060911030.017
regulation of homeostatic processGO:00328441820.017
negative regulation of protein phosphorylationGO:00019331260.017
multicellular organismal signalingGO:0035637910.017
inflammatory response to woundingGO:009059440.017
negative regulation of inflammatory responseGO:0050728610.016
negative regulation of cytokine productionGO:0001818840.016
energy derivation by oxidation of organic compoundsGO:0015980770.016
regulation of bindingGO:00510981110.016
cell differentiation involved in embryonic placenta developmentGO:0060706260.016
regulation of protein maturationGO:1903317960.016
renal sodium excretionGO:003581230.016
positive regulation of lipid metabolic processGO:0045834400.016
steroid biosynthetic processGO:0006694470.016
response to drugGO:0042493750.016
regulation of epidermal cell differentiationGO:0045604210.016
cell cell junction assemblyGO:0007043270.016
regenerationGO:0031099380.016
positive regulation of protein modification processGO:00314012990.016
nucleobase containing small molecule metabolic processGO:00550863520.016
engulfment of apoptotic cellGO:004365230.016
regulation of cellular response to stressGO:00801351590.016
phospholipid metabolic processGO:0006644870.016
negative regulation of phosphorylationGO:00423261660.016
fat cell differentiationGO:00454441600.015
polyol metabolic processGO:0019751260.015
androgen biosynthetic processGO:000670240.015
response to phenylpropanoidGO:0080184220.015
intracellular receptor signaling pathwayGO:0030522740.015
zymogen activationGO:0031638410.015
cell activation involved in immune responseGO:00022631260.015
membrane organizationGO:00610242450.015
positive regulation of hormone secretionGO:0046887380.015
regulation of systemic arterial blood pressure by hormoneGO:0001990250.015
diterpenoid biosynthetic processGO:001610270.015
cellular response to extracellular stimulusGO:0031668810.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
cation homeostasisGO:00550802120.015
vascular process in circulatory systemGO:0003018620.015
cellular modified amino acid metabolic processGO:0006575630.015
response to hypoxiaGO:0001666580.015
regulation of cysteine type endopeptidase activityGO:2000116650.015
regulation of transmembrane transportGO:00347621280.014
membrane lipid biosynthetic processGO:0046467320.014
purine containing compound metabolic processGO:00725213110.014
porphyrin containing compound metabolic processGO:0006778220.014
regulation of apoptotic signaling pathwayGO:20012331970.014
kidney developmentGO:00018222130.014
retinoic acid biosynthetic processGO:000213870.014
establishment of skin barrierGO:0061436140.014
chemokine productionGO:0032602340.014
posttranscriptional regulation of gene expressionGO:00106081550.014
lipid transportGO:0006869980.014
cellular nitrogen compound catabolic processGO:00442702800.014
divalent metal ion transportGO:00708381720.014
heart contractionGO:0060047930.014
positive regulation of growthGO:00459271040.014
regulation of lipid biosynthetic processGO:0046890540.014
regulation of thyroid hormone generationGO:200060940.014
epithelial tube morphogenesisGO:00605623030.014
organic cyclic compound catabolic processGO:19013612950.014
digestionGO:0007586400.014
epithelial cell developmentGO:00020641590.014
muscle system processGO:00030121410.013
negative regulation of mapk cascadeGO:0043409650.013
nucleotide metabolic processGO:00091173320.013
positive regulation of transferase activityGO:00513471670.013
actin mediated cell contractionGO:0070252150.013
response to stilbenoidGO:0035634220.013
positive regulation of nervous system developmentGO:00519622210.013
regulation of blood circulationGO:1903522930.013
keratinocyte proliferationGO:0043616210.013
9 cis retinoic acid biosynthetic processGO:004290450.013
multicellular organismal homeostasisGO:00488711640.013
negative regulation of defense responseGO:0031348770.013
response to oxygen levelsGO:0070482620.013
cellular metal ion homeostasisGO:00068751510.013
response to testosteroneGO:003357430.013
response to peptide hormoneGO:00434341270.013
regulation of peptide secretionGO:0002791770.013
reactive nitrogen species metabolic processGO:200105700.013
response to peptideGO:19016521360.013
intracellular protein transportGO:00068862040.013
response to vitamin dGO:003328030.013
renal tubule developmentGO:0061326870.013
lymphocyte proliferationGO:00466511640.013
metal ion homeostasisGO:00550651890.013
muscle tissue developmentGO:00605373080.013
regulation of engulfment of apoptotic cellGO:190107420.013
carbohydrate homeostasisGO:00335001280.012
myeloid cell differentiationGO:00300992330.012
response to oxidative stressGO:00069791230.012
negative regulation of phosphate metabolic processGO:00459361840.012
carboxylic acid catabolic processGO:0046395510.012
heme metabolic processGO:0042168160.012
9 cis retinoic acid metabolic processGO:004290550.012
response to light stimulusGO:00094161350.012
regulation of renin secretion into blood streamGO:190013340.012
regulation of protein secretionGO:0050708820.012
regulation of cell motilityGO:20001452360.012
connective tissue replacement involved in inflammatory response wound healingGO:000224830.012
wound healing involved in inflammatory responseGO:000224640.012
reactive oxygen species biosynthetic processGO:190340980.012
cell adhesionGO:00071553290.012
cellular response to acid chemicalGO:0071229680.012
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.012
regulation of chemokine productionGO:0032642300.012
acylglycerol metabolic processGO:0006639550.012
sensory perception of painGO:0019233470.012
mitochondrion organizationGO:00070051340.012
endocytosisGO:00068971680.012
regulation of vesicle mediated transportGO:00606271390.012
homeostasis of number of cellsGO:00488722100.012
cellular response to tumor necrosis factorGO:0071356210.012
leukocyte apoptotic processGO:0071887710.012
regulation of interleukin 6 productionGO:0032675550.012
gluconeogenesisGO:0006094390.012
neuronal action potentialGO:0019228540.011
compound eye developmentGO:004874910.011
negative regulation of phosphorus metabolic processGO:00105631840.011
endomembrane system organizationGO:00102561470.011
insulin receptor signaling pathwayGO:0008286490.011
terpenoid biosynthetic processGO:001611470.011
isoprenoid biosynthetic processGO:000829990.011
body fluid secretionGO:0007589530.011
mapk cascadeGO:00001652810.011
organophosphate biosynthetic processGO:00904071220.011
toxin metabolic processGO:000940450.011
monosaccharide transportGO:0015749580.011
monovalent inorganic cation homeostasisGO:0055067330.011
cellular response to dna damage stimulusGO:00069742070.011
fat soluble vitamin metabolic processGO:0006775110.011
oligopeptide transmembrane transportGO:003567240.011
positive regulation of cell deathGO:00109422240.011
regulation of lymphocyte differentiationGO:00456191070.011
t cell differentiationGO:00302171740.011
lymphocyte apoptotic processGO:0070227540.011
calcium ion transportGO:00068161590.011
regulation of systemic arterial blood pressureGO:0003073610.011
positive regulation of cell developmentGO:00107202370.011
cellular ion homeostasisGO:00068731650.011
phenol containing compound metabolic processGO:0018958600.011
nucleocytoplasmic transportGO:00069131390.011
regulation of leukocyte differentiationGO:19021051590.011
regulation of lymphocyte apoptotic processGO:0070228410.011
carbohydrate transportGO:0008643620.011
positive regulation of cell growthGO:0030307330.011
synaptic transmissionGO:00072683290.011
regulation of protein serine threonine kinase activityGO:00719001570.011
response to starvationGO:0042594650.011
inter male aggressive behaviorGO:000212130.011
regulation of cytoplasmic transportGO:19036491120.010
antibacterial peptide biosynthetic processGO:000278020.010
regulation of glucose metabolic processGO:0010906600.010
response to xenobiotic stimulusGO:0009410130.010
vitamin biosynthetic processGO:000911070.010
positive regulation of apoptotic processGO:00430652170.010
regulation of cell migrationGO:00303342190.010
small gtpase mediated signal transductionGO:0007264970.010
monocarboxylic acid transportGO:0015718440.010
heart processGO:0003015940.010
positive regulation of cell activationGO:00508671580.010
cellular response to calcium ionGO:0071277140.010
calcium ion homeostasisGO:00550741270.010
cellular carbohydrate metabolic processGO:00442621190.010
lung developmentGO:00303241640.010

Defb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.021
disease of anatomical entityDOID:700.021
hematopoietic system diseaseDOID:7400.021
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
vascular diseaseDOID:17800.017
cardiovascular system diseaseDOID:128700.017
disease of metabolismDOID:001466700.014
organ system cancerDOID:005068600.013