Mus musculus

31 known processes

Zmpste24

zinc metallopeptidase, STE24 homolog (S. cerevisiae)

(Aliases: MADB,D030046F19,STE24,Ste24p,Face-1,FACE1,A530043O15Rik)

Zmpste24 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.105
amine metabolic processGO:0009308450.080
regulation of cellular amino acid metabolic processGO:000652150.073
cellular amino acid metabolic processGO:00065201030.073
intracellular protein transportGO:00068862040.071
regulation of cellular amine metabolic processGO:0033238200.069
ion transmembrane transportGO:00342203610.068
negative regulation of molecular functionGO:00440922580.067
cation transportGO:00068123990.066
transmembrane transportGO:00550854120.064
positive regulation of cellular amine metabolic processGO:003324050.062
activation of nf kappab inducing kinase activityGO:000725040.057
positive regulation of apoptotic processGO:00430652170.056
peptidyl amino acid modificationGO:00181933360.056
cytoplasmic transportGO:00164822340.055
regulation of transferase activityGO:00513382630.052
small gtpase mediated signal transductionGO:0007264970.051
cellular ketone metabolic processGO:0042180840.051
skeletal system developmentGO:00015013560.049
membrane lipid biosynthetic processGO:0046467320.048
positive regulation of cellular amino acid metabolic processGO:004576430.047
ras protein signal transductionGO:0007265770.046
glycerolipid metabolic processGO:00464861220.045
regulation of intracellular transportGO:00323861590.044
cellular homeostasisGO:00197252400.043
cellular amine metabolic processGO:0044106440.043
regulation of protein kinase activityGO:00458592320.042
regulation of protein localizationGO:00328802310.042
regulation of cellular ketone metabolic processGO:0010565660.041
regulation of apoptotic signaling pathwayGO:20012331970.041
mapk cascadeGO:00001652810.039
metal ion homeostasisGO:00550651890.038
leukocyte differentiationGO:00025213420.037
positive regulation of protein kinase activityGO:00458601440.037
regulation of defense responseGO:00313472330.036
apoptotic signaling pathwayGO:00971903060.036
positive regulation of protein phosphorylationGO:00019342420.036
sphingolipid biosynthetic processGO:0030148260.036
lipid biosynthetic processGO:00086101790.035
carbohydrate metabolic processGO:00059752300.035
cellular amide metabolic processGO:0043603580.035
cellular ion homeostasisGO:00068731650.034
cation transmembrane transportGO:00986552660.034
cellular response to lipidGO:00713961450.033
cellular chemical homeostasisGO:00550822150.033
protein localization to membraneGO:00726571080.033
sphingolipid metabolic processGO:0006665450.032
dna metabolic processGO:00062593030.032
membrane organizationGO:00610242450.031
regulation of mapk cascadeGO:00434082480.031
cation homeostasisGO:00550802120.031
organonitrogen compound biosynthetic processGO:19015661920.031
myeloid cell differentiationGO:00300992330.030
protein localization to organelleGO:00333651850.030
divalent metal ion transportGO:00708381720.030
protein targetingGO:00066051430.030
calcium ion transportGO:00068161590.030
cellular metal ion homeostasisGO:00068751510.029
inorganic cation transmembrane transportGO:00986622070.029
negative regulation of cell adhesion mediated by integrinGO:003362920.029
protein maturationGO:00516041760.029
protein processingGO:00164851630.028
endocytosisGO:00068971680.028
rho protein signal transductionGO:0007266320.028
intrinsic apoptotic signaling pathwayGO:00971931320.028
reactive oxygen species metabolic processGO:0072593840.028
striated muscle tissue developmentGO:00147062930.027
heterocycle catabolic processGO:00467002800.027
lipid transportGO:0006869980.027
inorganic ion transmembrane transportGO:00986602340.027
regulation of ion transportGO:00432692150.027
regulation of protein serine threonine kinase activityGO:00719001570.027
homeostasis of number of cellsGO:00488722100.026
nucleobase containing small molecule metabolic processGO:00550863520.026
regulation of kinase activityGO:00435492490.026
organic hydroxy compound metabolic processGO:19016152030.025
endomembrane system organizationGO:00102561470.025
positive regulation of programmed cell deathGO:00430682180.025
cellular divalent inorganic cation homeostasisGO:00725031270.025
circulatory system processGO:00030131970.025
mitotic cell cycle processGO:19030471590.025
regulation of cell activationGO:00508652890.025
regulation of body fluid levelsGO:00508781620.025
nitrogen compound transportGO:00717052710.025
immune effector processGO:00022523210.025
calcium ion homeostasisGO:00550741270.024
establishment of protein localization to organelleGO:00725941180.024
neuron deathGO:00709971540.024
purine ribonucleotide metabolic processGO:00091502900.024
synaptic transmissionGO:00072683290.024
muscle cell differentiationGO:00426922610.024
carboxylic acid biosynthetic processGO:0046394860.023
organophosphate catabolic processGO:00464342320.023
organic hydroxy compound transportGO:0015850930.023
organonitrogen compound catabolic processGO:19015652640.023
nuclear transportGO:00511691390.023
positive regulation of kinase activityGO:00336741550.023
regulation of metal ion transportGO:00109591060.023
positive regulation of transferase activityGO:00513471670.023
t cell activationGO:00421102890.022
divalent inorganic cation homeostasisGO:00725071380.022
ceramide biosynthetic processGO:0046513200.022
cellular response to dna damage stimulusGO:00069742070.022
positive regulation of protein serine threonine kinase activityGO:00719021060.022
divalent inorganic cation transportGO:00725111780.022
sensory perceptionGO:00076002450.022
negative regulation of protein metabolic processGO:00512482820.022
sulfur compound metabolic processGO:00067901000.022
glycoprotein metabolic processGO:00091001160.022
regulation of nucleocytoplasmic transportGO:0046822730.022
protein import into nucleusGO:0006606950.022
monocarboxylic acid metabolic processGO:00327871910.021
peptidyl serine modificationGO:0018209830.021
carbohydrate derivative biosynthetic processGO:19011371830.021
positive regulation of protein modification processGO:00314012990.021
dephosphorylationGO:00163111290.021
compound eye developmentGO:004874910.021
chromatin organizationGO:00063252060.021
positive regulation of map kinase activityGO:0043406840.021
protein importGO:00170381010.021
fatty acid metabolic processGO:00066311210.021
negative regulation of apoptotic signaling pathwayGO:20012341040.021
regulation of membrane potentialGO:00423911920.021
nucleocytoplasmic transportGO:00069131390.021
regulation of hormone levelsGO:00108172110.021
cell adhesionGO:00071553290.020
response to organonitrogen compoundGO:00102432460.020
multicellular organismal homeostasisGO:00488711640.020
membrane lipid metabolic processGO:0006643530.020
organelle localizationGO:00516401790.020
blood circulationGO:00080151950.020
regulation of cellular response to stressGO:00801351590.020
nucleotide metabolic processGO:00091173320.020
alcohol metabolic processGO:00060661160.020
myeloid leukocyte differentiationGO:00025731190.020
negative regulation of cellular amino acid metabolic processGO:004576300.019
response to organic cyclic compoundGO:00140701980.019
cellular protein complex assemblyGO:00436231160.019
gland developmentGO:00487323300.019
regulation of cell migrationGO:00303342190.019
phagocytosisGO:0006909660.019
embryonic organ morphogenesisGO:00485622760.019
negative regulation of phosphate metabolic processGO:00459361840.019
cytokine productionGO:00018163190.019
regulation of protein transportGO:00512231630.019
sequestering of calcium ionGO:0051208180.019
negative regulation of cellular protein metabolic processGO:00322692470.018
regulation of homeostatic processGO:00328441820.018
gonad morphogenesisGO:003526210.018
response to insulinGO:00328681000.018
nucleoside phosphate metabolic processGO:00067533380.018
male gamete generationGO:00482322850.018
regulation of intracellular protein transportGO:0033157820.018
regulation of secretion by cellGO:19035302490.018
regulation of cytokine productionGO:00018172660.018
positive regulation of intracellular transportGO:0032388700.018
phospholipid metabolic processGO:0006644870.018
cellular calcium ion homeostasisGO:00068741190.018
regulation of map kinase activityGO:00434051200.018
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
response to oxidative stressGO:00069791230.017
sequestering of metal ionGO:0051238190.017
positive regulation of mapk cascadeGO:00434101700.017
ossificationGO:00015032160.017
cellular response to organonitrogen compoundGO:00714171450.017
ribose phosphate metabolic processGO:00196932910.017
regulation of calcium ion transportGO:0051924690.017
regulation of endopeptidase activityGO:0052548890.017
spermatogenesisGO:00072832840.017
neutral lipid metabolic processGO:0006638570.017
peptide secretionGO:00027901140.017
regulation of organelle organizationGO:00330432890.017
wound healingGO:00420601570.017
lipid localizationGO:00108761260.017
mitotic cell cycleGO:00002781950.017
negative regulation of phosphorylationGO:00423261660.017
organelle assemblyGO:00709251770.016
heart morphogenesisGO:00030071780.016
muscle contractionGO:00069361010.016
organic acid biosynthetic processGO:0016053860.016
cellular response to abiotic stimulusGO:0071214560.016
glucose homeostasisGO:00425931280.016
amide transportGO:00428861380.016
glycerophospholipid metabolic processGO:0006650710.016
action potentialGO:0001508780.016
nuclear importGO:0051170950.016
cell type specific apoptotic processGO:00972852680.016
multicellular organism growthGO:00352641610.016
glycoprotein biosynthetic processGO:0009101890.016
purine nucleoside metabolic processGO:00422782410.016
oxidation reduction processGO:00551143420.016
small molecule biosynthetic processGO:00442831320.016
muscle tissue developmentGO:00605373080.016
purine nucleotide metabolic processGO:00061633020.016
organic cyclic compound catabolic processGO:19013612950.016
purine nucleoside catabolic processGO:00061522050.016
mitochondrion organizationGO:00070051340.016
sensory organ morphogenesisGO:00905962420.016
positive regulation of ion transportGO:0043270650.016
regulation of cytoplasmic transportGO:19036491120.015
defense response to bacteriumGO:00427421190.015
gonad developmentGO:00084061410.015
methylationGO:00322591340.015
regulation of protein localization to nucleusGO:1900180600.015
purine containing compound metabolic processGO:00725213110.015
skeletal system morphogenesisGO:00487052030.015
urogenital system developmentGO:00016552610.015
anion transportGO:00068201770.015
coagulationGO:0050817780.015
regulation of defense response to bacteriumGO:190042430.015
peptidyl tyrosine modificationGO:00182121450.015
nucleotide catabolic processGO:00091662170.015
adult behaviorGO:00305341350.015
negative regulation of transferase activityGO:0051348850.015
regulation of interleukin 8 productionGO:003267730.015
antimicrobial peptide productionGO:000277520.015
posttranscriptional regulation of gene expressionGO:00106081550.015
zygotic determination of anterior posterior axis embryoGO:000735430.015
organophosphate biosynthetic processGO:00904071220.014
response to lipopolysaccharideGO:00324961280.014
lateral inhibitionGO:004633110.014
fertilizationGO:00095661270.014
regulation of action potentialGO:009890040.014
cellular nitrogen compound catabolic processGO:00442702800.014
antimicrobial peptide biosynthetic processGO:000277720.014
localization within membraneGO:005166840.014
stress activated mapk cascadeGO:0051403800.014
regulation of cysteine type endopeptidase activityGO:2000116650.014
plasma membrane organizationGO:0007009900.014
positive regulation of cell deathGO:00109422240.014
nuclear membrane organizationGO:007176340.014
regulation of peptidase activityGO:0052547960.014
actin cytoskeleton organizationGO:00300362200.014
cellular response to hormone stimulusGO:00328701500.014
er nucleus signaling pathwayGO:0006984270.014
macromolecule glycosylationGO:0043413550.014
negative regulation of cellular amine metabolic processGO:003323910.014
antibacterial peptide productionGO:000277820.014
chemotaxisGO:00069352470.014
positive regulation of secretionGO:00510471300.014
regulation of secretionGO:00510462740.014
ribonucleotide metabolic processGO:00092592910.014
histone modificationGO:00165701590.014
response to epidermal growth factorGO:007084940.014
leukocyte proliferationGO:00706611720.014
camera type eye developmentGO:00430102660.014
single fertilizationGO:0007338820.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.014
regulation of mitotic cell cycleGO:00073461260.014
forebrain developmentGO:00309003020.013
carbohydrate homeostasisGO:00335001280.013
regulation of leukocyte differentiationGO:19021051590.013
cellular modified amino acid metabolic processGO:0006575630.013
regulation of proteolysisGO:00301621640.013
lymphocyte proliferationGO:00466511640.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
single organism nuclear importGO:1902593950.013
protein localization to nucleusGO:00345041210.013
hormone secretionGO:00468791280.013
regulation of cellular catabolic processGO:00313292420.013
regulation of vesicle mediated transportGO:00606271390.013
stress activated protein kinase signaling cascadeGO:0031098810.013
establishment of organelle localizationGO:00516561220.013
regulation of purine nucleotide catabolic processGO:00331211220.013
limb developmentGO:00601731660.013
myotube differentiationGO:00149021050.013
regulation of hydrolase activityGO:00513362460.013
skeletal muscle organ developmentGO:00605381630.013
negative regulation of cytokine productionGO:0001818840.013
regulation of system processGO:00440572000.013
protein modification by small protein conjugationGO:00324461870.013
regulation of anatomical structure sizeGO:00900661780.013
cell growthGO:00160491300.013
hemostasisGO:0007599780.013
i kappab kinase nf kappab signalingGO:0007249850.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
lymphocyte differentiationGO:00300982420.013
sterol transmembrane transportGO:003538220.012
monocarboxylic acid biosynthetic processGO:0072330610.012
negative regulation of immune system processGO:00026832090.012
peptide transportGO:00158331330.012
ceramide metabolic processGO:0006672310.012
multicellular organismal signalingGO:0035637910.012
glycosyl compound catabolic processGO:19016582060.012
blood coagulationGO:0007596760.012
inflammatory responseGO:00069542440.012
lymphocyte mediated immunityGO:00024491390.012
regulation of blood pressureGO:0008217930.012
cytosolic calcium ion transportGO:0060401480.012
angiogenesisGO:00015252010.012
peptidyl tyrosine phosphorylationGO:00181081430.012
ear developmentGO:00435832000.012
positive regulation of growthGO:00459271040.012
muscle cell developmentGO:00550011330.012
negative regulation of intracellular signal transductionGO:19025321670.012
response to steroid hormoneGO:0048545560.012
blood vessel morphogenesisGO:00485142850.012
anatomical structure homeostasisGO:00602491450.012
negative regulation of phosphorus metabolic processGO:00105631840.012
response to molecule of bacterial originGO:00022371430.012
organelle fissionGO:00482851700.012
positive regulation of antibacterial peptide biosynthetic processGO:000696310.012
negative regulation of sterol transportGO:003237240.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
neuron apoptotic processGO:00514021420.012
histone h4 k16 acetylationGO:004398430.012
aromatic compound catabolic processGO:00194392860.012
regulation of neuron deathGO:19012141340.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
calcium mediated signalingGO:0019722460.012
insulin secretionGO:0030073890.012
antibacterial peptide biosynthetic processGO:000278020.012
negative regulation of cellular component organizationGO:00511291940.012
purine ribonucleoside metabolic processGO:00461282410.012
regulation of chromatin silencingGO:003193520.012
respiratory system developmentGO:00605411900.012
organ regenerationGO:003110020.012
calcium ion transport into cytosolGO:0060402480.012
myosin filament assemblyGO:003103420.012
canonical wnt signaling pathwayGO:00600701300.012
locomotory behaviorGO:00076261950.011
peptide metabolic processGO:0006518460.011
fat cell differentiationGO:00454441600.011
telencephalon developmentGO:00215371860.011
positive regulation of defense responseGO:00313491240.011
ribonucleoside catabolic processGO:00424542060.011
maintenance of locationGO:0051235890.011
serine phosphorylation of stat proteinGO:004250130.011
ribonucleoside metabolic processGO:00091192450.011
cellular response to insulin stimulusGO:0032869780.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
response to endoplasmic reticulum stressGO:0034976530.011
response to acid chemicalGO:00011011110.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
purine ribonucleoside catabolic processGO:00461302050.011
immune response activating signal transductionGO:00027571160.011
cellular response to cytokine stimulusGO:00713451890.011
regulation of exit from mitosisGO:000709610.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.011
cytosolic calcium ion homeostasisGO:0051480700.011
positive regulation of protein transportGO:0051222930.011
regulation of feeding behaviorGO:006025930.011
adult locomotory behaviorGO:0008344910.011
response to extracellular stimulusGO:00099911270.011
regulation of striated muscle cell differentiationGO:0051153810.011
actin filament based movementGO:0030048230.011
transmission of nerve impulseGO:0019226760.011
negative regulation of protein modification processGO:00314001630.011
lactationGO:0007595250.011
regulation of protein import into nucleus translocationGO:003315820.011
tissue remodelingGO:00487711020.011
activation of mapk activityGO:0000187590.011
regulation of cell cycleGO:00517262810.011
cellular carbohydrate metabolic processGO:00442621190.011
cellular response to biotic stimulusGO:0071216920.011
nucleoside phosphate catabolic processGO:19012922220.011
positive regulation of glucose transportGO:0010828160.011
regulation of multi organism processGO:00439001110.011
covalent chromatin modificationGO:00165691630.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.011
nucleoside monophosphate metabolic processGO:0009123850.011
regulation of purine nucleotide metabolic processGO:19005421690.011
regulation of t cell activationGO:00508631700.011
triglyceride metabolic processGO:0006641510.011
regulation of cell projection organizationGO:00313442060.011
epithelial cell developmentGO:00020641590.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
cell activation involved in immune responseGO:00022631260.011
regulation of cell motilityGO:20001452360.011
protein kinase b signalingGO:0043491740.010
interleukin 8 productionGO:003263740.010
establishment of vesicle localizationGO:0051650810.010
macromolecule catabolic processGO:00090572810.010
organic anion transportGO:00157111370.010
positive regulation of cell motilityGO:20001471160.010
positive regulation of cell developmentGO:00107202370.010
small molecule catabolic processGO:0044282710.010
carbohydrate derivative catabolic processGO:19011362310.010
myosin filament organizationGO:003103330.010
sulfur compound biosynthetic processGO:0044272370.010
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.010
proteolysis involved in cellular protein catabolic processGO:00516031470.010
positive regulation of cell migrationGO:00303351090.010
positive regulation of secretion by cellGO:19035321140.010
retrograde transport endosome to golgiGO:004214720.010
response to peptide hormoneGO:00434341270.010
cellular response to steroid hormone stimulusGO:0071383330.010
response to peptideGO:19016521360.010
cellular response to peptideGO:1901653920.010
translationGO:0006412930.010
cellular macromolecule catabolic processGO:00442652060.010
positive regulation of innate immune responseGO:0045089800.010
jak stat cascadeGO:0007259420.010
regulation of establishment of protein localizationGO:00702011810.010
regulation of lipid metabolic processGO:00192161180.010

Zmpste24 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.040
musculoskeletal system diseaseDOID:1700.031
immune system cancerDOID:006008300.031
disease of cellular proliferationDOID:1456600.031
cancerDOID:16200.031
organ system cancerDOID:005068600.031
hematologic cancerDOID:253100.031
integumentary system diseaseDOID:1600.029
inherited metabolic disorderDOID:65500.027
disease of metabolismDOID:001466700.027
connective tissue diseaseDOID:6500.026
osteochondrodysplasiaDOID:225600.026
bone development diseaseDOID:008000600.026
bone diseaseDOID:008000100.026
neuropathyDOID:87000.022
thoracic cancerDOID:509300.016
sensory system diseaseDOID:005015500.014
immune system diseaseDOID:291400.014
cardiovascular system diseaseDOID:128700.011
central nervous system diseaseDOID:33100.010
neurodegenerative diseaseDOID:128900.010
lipid metabolism disorderDOID:314600.010