IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Hsdl2

hydroxysteroid dehydrogenase like 2

(Aliases: 2610207I16Rik)

Ensembl: ENSMUSG00000028383
Entrez: 72479
UniProtKB: Q2TPA8
UniProtKB: B1AX78

Process Predictions
Disease Predictions

Hsdl2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
lipid oxidation	GO:0034440	29	0.978
fatty acid oxidation	GO:0019395	28	0.947
cellular lipid catabolic process	GO:0044242	52	0.929
monocarboxylic acid metabolic process	GO:0032787	191	0.889
lipid catabolic process	GO:0016042	69	0.881
monocarboxylic acid catabolic process	GO:0072329	27	0.855
fatty acid metabolic process	GO:0006631	121	0.831
lipid modification	GO:0030258	65	0.783
organic acid catabolic process	GO:0016054	51	0.727
fatty acid beta oxidation	GO:0006635	16	0.666
carnitine metabolic process	GO:0009437	7	0.635
carboxylic acid catabolic process	GO:0046395	51	0.626
peroxisome organization	GO:0007031	7	0.577
organic acid biosynthetic process	GO:0016053	86	0.569
very long chain fatty acid catabolic process	GO:0042760	2	0.542
small molecule catabolic process	GO:0044282	71	0.519
thioester metabolic process	GO:0035383	19	0.426
fatty acid catabolic process	GO:0009062	25	0.424
lipid biosynthetic process	GO:0008610	179	0.418
very long chain fatty acid metabolic process	GO:0000038	8	0.415
establishment of protein localization to peroxisome	GO:0072663	4	0.383
oxidation reduction process	GO:0055114	342	0.359
amino acid betaine metabolic process	GO:0006577	7	0.348
cellular ketone metabolic process	GO:0042180	84	0.339
cellular lipid metabolic process	GO:0044255	323	0.300
small molecule biosynthetic process	GO:0044283	132	0.296
organic anion transport	GO:0015711	137	0.232
anion transport	GO:0006820	177	0.211
purine nucleoside metabolic process	GO:0042278	241	0.198
peroxisomal transport	GO:0043574	4	0.158
steroid metabolic process	GO:0008202	119	0.157
nucleobase containing small molecule metabolic process	GO:0055086	352	0.138
organic hydroxy compound metabolic process	GO:1901615	203	0.136
carboxylic acid biosynthetic process	GO:0046394	86	0.130
membrane organization	GO:0061024	245	0.120
monocarboxylic acid biosynthetic process	GO:0072330	61	0.119
nucleoside phosphate metabolic process	GO:0006753	338	0.114
purine containing compound metabolic process	GO:0072521	311	0.112
glycerolipid metabolic process	GO:0046486	122	0.111
protein homooligomerization	GO:0051260	43	0.108
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.104
fatty acid alpha oxidation	GO:0001561	2	0.099
ribonucleoside metabolic process	GO:0009119	245	0.095
protein oligomerization	GO:0051259	67	0.094
purine ribonucleoside metabolic process	GO:0046128	241	0.091
medium chain fatty acid metabolic process	GO:0051791	1	0.091
nucleotide metabolic process	GO:0009117	332	0.090
heterocycle catabolic process	GO:0046700	280	0.085
ribose phosphate metabolic process	GO:0019693	291	0.083
generation of precursor metabolites and energy	GO:0006091	103	0.083
purine ribonucleotide metabolic process	GO:0009150	290	0.083
glycosyl compound metabolic process	GO:1901657	246	0.082
progesterone biosynthetic process	GO:0006701	1	0.076
nucleoside triphosphate metabolic process	GO:0009141	230	0.075
organonitrogen compound catabolic process	GO:1901565	264	0.074
purine nucleotide metabolic process	GO:0006163	302	0.073
regulation of cellular ketone metabolic process	GO:0010565	66	0.072
ribonucleotide metabolic process	GO:0009259	291	0.072
endomembrane system organization	GO:0010256	147	0.070
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.069
cofactor metabolic process	GO:0051186	80	0.068
lipid localization	GO:0010876	126	0.068
intracellular protein transport	GO:0006886	204	0.068
sulfur compound metabolic process	GO:0006790	100	0.066
glutamine family amino acid biosynthetic process	GO:0009084	2	0.065
lipid transport	GO:0006869	98	0.060
regulation of intracellular transport	GO:0032386	159	0.060
pyruvate transport	GO:0006848	2	0.055
nucleoside monophosphate metabolic process	GO:0009123	85	0.054
nucleoside metabolic process	GO:0009116	246	0.052
regulation of cellular catabolic process	GO:0031329	242	0.051
mitochondrial transport	GO:0006839	36	0.051
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.050
protein localization to peroxisome	GO:0072662	4	0.050
organic acid transport	GO:0015849	101	0.050
cellular amine metabolic process	GO:0044106	44	0.050
cellular nitrogen compound catabolic process	GO:0044270	280	0.049
atp metabolic process	GO:0046034	75	0.045
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.041
alcohol biosynthetic process	GO:0046165	43	0.041
pyruvate transmembrane transport	GO:1901475	2	0.041
phospholipid metabolic process	GO:0006644	87	0.040
organic hydroxy compound biosynthetic process	GO:1901617	77	0.040
glycerophospholipid metabolic process	GO:0006650	71	0.038
purine containing compound catabolic process	GO:0072523	213	0.038
acylglycerol metabolic process	GO:0006639	55	0.037
fatty acid biosynthetic process	GO:0006633	41	0.036
protein localization to membrane	GO:0072657	108	0.035
amine metabolic process	GO:0009308	45	0.035
fatty acyl coa metabolic process	GO:0035337	4	0.035
organic cyclic compound catabolic process	GO:1901361	295	0.035
organophosphate catabolic process	GO:0046434	232	0.034
sulfur compound biosynthetic process	GO:0044272	37	0.032
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.032
regulation of lipid metabolic process	GO:0019216	118	0.032
purine ribonucleoside catabolic process	GO:0046130	205	0.032
negative regulation of fatty acid metabolic process	GO:0045922	10	0.031
protein catabolic process	GO:0030163	221	0.031
long chain fatty acid metabolic process	GO:0001676	26	0.031
c21 steroid hormone biosynthetic process	GO:0006700	3	0.031
carboxylic acid transport	GO:0046942	100	0.031
protein import into peroxisome matrix	GO:0016558	3	0.031
ribonucleotide catabolic process	GO:0009261	208	0.030
glycogen metabolic process	GO:0005977	32	0.030
regulation of fatty acid metabolic process	GO:0019217	28	0.029
monocarboxylic acid transport	GO:0015718	44	0.029
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.028
regulation of apoptotic signaling pathway	GO:2001233	197	0.028
macromolecule catabolic process	GO:0009057	281	0.028
protein targeting	GO:0006605	143	0.028
purine nucleoside catabolic process	GO:0006152	205	0.028
protein tetramerization	GO:0051262	23	0.026
cytoplasmic transport	GO:0016482	234	0.026
alcohol metabolic process	GO:0006066	116	0.026
positive regulation of protein modification process	GO:0031401	299	0.025
apoptotic signaling pathway	GO:0097190	306	0.025
carbohydrate derivative catabolic process	GO:1901136	231	0.025
protein targeting to peroxisome	GO:0006625	4	0.025
maintenance of location	GO:0051235	89	0.024
regulation of steroid metabolic process	GO:0019218	39	0.024
acyl coa metabolic process	GO:0006637	19	0.024
microtubule based process	GO:0007017	236	0.024
cellular macromolecule catabolic process	GO:0044265	206	0.024
nucleotide catabolic process	GO:0009166	217	0.024
response to nutrient levels	GO:0031667	109	0.023
lipoprotein metabolic process	GO:0042157	43	0.023
glycosyl compound catabolic process	GO:1901658	206	0.023
histone modification	GO:0016570	159	0.022
regulation of lipid biosynthetic process	GO:0046890	54	0.022
nucleoside phosphate catabolic process	GO:1901292	222	0.022
innate immune response	GO:0045087	157	0.022
response to copper ion	GO:0046688	3	0.022
phosphatidylethanolamine metabolic process	GO:0046337	2	0.022
glucose metabolic process	GO:0006006	92	0.022
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.021
aromatic compound catabolic process	GO:0019439	286	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.021
purine nucleotide catabolic process	GO:0006195	211	0.020
regulation of carbohydrate metabolic process	GO:0006109	75	0.020
cellular response to cytokine stimulus	GO:0071345	189	0.020
negative regulation of phosphate metabolic process	GO:0045936	184	0.019
phagocytosis	GO:0006909	66	0.019
regulation of organelle organization	GO:0033043	289	0.019
negative regulation of cellular component organization	GO:0051129	194	0.019
leukocyte differentiation	GO:0002521	342	0.019
acetyl coa biosynthetic process	GO:0006085	5	0.018
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.018
cellular biogenic amine metabolic process	GO:0006576	28	0.018
negative regulation of immune system process	GO:0002683	209	0.018
negative regulation of cellular protein metabolic process	GO:0032269	247	0.018
positive regulation of intracellular transport	GO:0032388	70	0.018
response to extracellular stimulus	GO:0009991	127	0.018
establishment of protein localization to organelle	GO:0072594	118	0.018
hepaticobiliary system development	GO:0061008	67	0.018
negative regulation of molecular function	GO:0044092	258	0.018
reactive oxygen species metabolic process	GO:0072593	84	0.018
regulation of glucose metabolic process	GO:0010906	60	0.018
transmembrane transport	GO:0055085	412	0.017
exocytosis	GO:0006887	121	0.017
fatty acid transmembrane transport	GO:1902001	1	0.017
organonitrogen compound biosynthetic process	GO:1901566	192	0.017
nucleoside triphosphate catabolic process	GO:0009143	205	0.017
regulation of kinase activity	GO:0043549	249	0.017
glycerolipid biosynthetic process	GO:0045017	50	0.017
cellular carbohydrate metabolic process	GO:0044262	119	0.017
positive regulation of glycolytic process	GO:0045821	4	0.017
glycerophospholipid biosynthetic process	GO:0046474	32	0.017
liver development	GO:0001889	66	0.016
cellular amino acid metabolic process	GO:0006520	103	0.016
spermatid differentiation	GO:0048515	115	0.016
gonad development	GO:0008406	141	0.016
monosaccharide biosynthetic process	GO:0046364	44	0.016
regulation of cytoplasmic transport	GO:1903649	112	0.016
spermatogenesis	GO:0007283	284	0.016
plasma membrane organization	GO:0007009	90	0.016
organophosphate biosynthetic process	GO:0090407	122	0.016
adiponectin activated signaling pathway	GO:0033211	4	0.016
regulation of hormone levels	GO:0010817	211	0.016
negative regulation of phosphorus metabolic process	GO:0010563	184	0.016
purine ribonucleotide catabolic process	GO:0009154	208	0.015
response to starvation	GO:0042594	65	0.015
regulation of vesicle mediated transport	GO:0060627	139	0.015
acetyl coa biosynthetic process from pyruvate	GO:0006086	3	0.015
carbohydrate metabolic process	GO:0005975	230	0.015
triglyceride metabolic process	GO:0006641	51	0.015
male gamete generation	GO:0048232	285	0.015
nucleocytoplasmic transport	GO:0006913	139	0.015
hexose metabolic process	GO:0019318	98	0.015
response to growth factor	GO:0070848	198	0.015
regulation of nucleotide metabolic process	GO:0006140	169	0.015
nucleoside catabolic process	GO:0009164	206	0.015
protein localization to plasma membrane	GO:0072659	57	0.014
cellular response to hormone stimulus	GO:0032870	150	0.014
striated muscle tissue development	GO:0014706	293	0.014
regulation of transferase activity	GO:0051338	263	0.014
iron sulfur cluster assembly	GO:0016226	3	0.014
monosaccharide metabolic process	GO:0005996	106	0.014
sterol metabolic process	GO:0016125	58	0.014
glucan metabolic process	GO:0044042	32	0.014
i kappab kinase nf kappab signaling	GO:0007249	85	0.014
development of primary male sexual characteristics	GO:0046546	88	0.014
forebrain development	GO:0030900	302	0.014
gtp metabolic process	GO:0046039	144	0.014
negative regulation of organelle organization	GO:0010639	90	0.014
cellular glucan metabolic process	GO:0006073	32	0.014
regulation of secretion by cell	GO:1903530	249	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.013
energy derivation by oxidation of organic compounds	GO:0015980	77	0.013
ossification	GO:0001503	216	0.013
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.013
epithelial cell development	GO:0002064	159	0.013
regulation of mitochondrial fission	GO:0090140	3	0.013
branched chain amino acid catabolic process	GO:0009083	2	0.013
regulation of cell cycle	GO:0051726	281	0.013
mapk cascade	GO:0000165	281	0.013
nitrogen compound transport	GO:0071705	271	0.013
cardiac muscle tissue development	GO:0048738	130	0.013
response to organonitrogen compound	GO:0010243	246	0.013
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.013
fat cell differentiation	GO:0045444	160	0.013
inositol phosphate biosynthetic process	GO:0032958	6	0.013
ion transmembrane transport	GO:0034220	361	0.013
cell type specific apoptotic process	GO:0097285	268	0.013
regulation of cellular amino acid metabolic process	GO:0006521	5	0.013
response to drug	GO:0042493	75	0.012
germ cell development	GO:0007281	185	0.012
gtp catabolic process	GO:0006184	143	0.012
cellular response to organonitrogen compound	GO:0071417	145	0.012
positive regulation of cellular amine metabolic process	GO:0033240	5	0.012
guanosine containing compound metabolic process	GO:1901068	144	0.012
defense response to other organism	GO:0098542	197	0.012
response to oxidative stress	GO:0006979	123	0.012
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.012
fatty acid transport	GO:0015908	28	0.012
cargo loading into vesicle	GO:0035459	3	0.012
covalent chromatin modification	GO:0016569	163	0.012
neuron migration	GO:0001764	122	0.012
chromatin modification	GO:0016568	187	0.012
ribonucleoside catabolic process	GO:0042454	206	0.012
steroid biosynthetic process	GO:0006694	47	0.011
protein processing	GO:0016485	163	0.011
pyrimidine containing compound catabolic process	GO:0072529	3	0.011
protein homotetramerization	GO:0051289	12	0.011
regulation of cellular amine metabolic process	GO:0033238	20	0.011
positive regulation of transferase activity	GO:0051347	167	0.011
chromatin organization	GO:0006325	206	0.011
rna processing	GO:0006396	105	0.011
anion transmembrane transport	GO:0098656	71	0.011
organic hydroxy compound transport	GO:0015850	93	0.011
cellular protein catabolic process	GO:0044257	155	0.011
regulation of carbohydrate biosynthetic process	GO:0043255	40	0.011
cellular response to growth factor stimulus	GO:0071363	197	0.011
glycogen biosynthetic process	GO:0005978	14	0.011
regulation of mitochondrion organization	GO:0010821	27	0.011
hormone metabolic process	GO:0042445	86	0.011
regulation of protein kinase activity	GO:0045859	232	0.011
pyrimidine nucleobase metabolic process	GO:0006206	3	0.011
positive regulation of organelle organization	GO:0010638	128	0.011
sterol transport	GO:0015918	38	0.011
cholesterol transport	GO:0030301	38	0.011
coenzyme metabolic process	GO:0006732	52	0.011
polysaccharide metabolic process	GO:0005976	39	0.010
dna metabolic process	GO:0006259	303	0.010
positive regulation of steroid biosynthetic process	GO:0010893	4	0.010
regulation of membrane potential	GO:0042391	192	0.010
male sex differentiation	GO:0046661	109	0.010
gluconeogenesis	GO:0006094	39	0.010
cholesterol metabolic process	GO:0008203	56	0.010
hexose biosynthetic process	GO:0019319	39	0.010
negative regulation of protein metabolic process	GO:0051248	282	0.010
water soluble vitamin biosynthetic process	GO:0042364	3	0.010
g protein coupled receptor signaling pathway	GO:0007186	243	0.010

Hsdl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.110
inherited metabolic disorder	DOID:655	0.110
carbohydrate metabolic disorder	DOID:2978	0.022
hyperinsulinemic hypoglycemia	DOID:13317	0.022
lipid metabolism disorder	DOID:3146	0.016
disease of cellular proliferation	DOID:14566	0.014
nervous system disease	DOID:863	0.013
disease of anatomical entity	DOID:7	0.013
amino acid metabolic disorder	DOID:9252	0.010
organic acidemia	DOID:0060159	0.010

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